PSEN1 (presenilin 1) - Rat Genome Database

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Gene: PSEN1 (presenilin 1) Canis lupus familiaris
Analyze
Symbol: PSEN1
Name: presenilin 1
RGD ID: 12265224
Description: ENCODES a protein that exhibits aspartic endopeptidase activity, intramembrane cleaving (ortholog); endopeptidase activity (ortholog); peptidase activity (ortholog); INVOLVED IN amyloid precursor protein catabolic process (ortholog); amyloid precursor protein metabolic process (ortholog); amyloid-beta formation (ortholog); PARTICIPATES IN Notch signaling pathway; syndecan signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 3 (ortholog); Alzheimer's disease 4 (ortholog); FOUND IN aggresome (ortholog); cell surface (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: presenilin 1 (Alzheimer disease 3); presenilin-1; PS-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1846,495,551 - 46,569,532 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl846,495,624 - 46,569,532 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,188,004 - 46,253,311 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0846,719,986 - 46,800,157 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl846,720,051 - 46,800,135 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,399,068 - 46,464,638 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,414,872 - 46,480,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0846,805,794 - 46,871,397 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amyloid precursor protein catabolic process  (IEA,ISO)
amyloid precursor protein metabolic process  (IEA,ISS)
amyloid-beta formation  (IBA,IEA,ISO,ISS)
amyloid-beta metabolic process  (IEA,ISO)
apoptotic process  (IEA)
apoptotic signaling pathway  (IEA,ISO)
astrocyte activation  (IEA)
astrocyte activation involved in immune response  (IEA)
autophagosome assembly  (IEA,ISO)
autophagy  (IEA,ISO)
blood vessel development  (IEA,ISO)
brain development  (IEA,ISO)
brain morphogenesis  (IEA,ISO)
Cajal-Retzius cell differentiation  (IEA,ISO)
calcium ion homeostasis  (IBA)
calcium ion transmembrane transport  (IEA)
cell adhesion  (IEA)
cell fate specification  (IEA,ISO)
cell-cell adhesion  (IEA,ISO)
cellular response to amyloid-beta  (IEA)
cerebellum development  (ISO)
cerebral cortex cell migration  (IEA,ISO)
cerebral cortex development  (IEA,ISO)
choline transport  (IEA,ISO)
DNA damage response  (IEA,ISO)
dorsal/ventral neural tube patterning  (IEA,ISO)
embryonic limb morphogenesis  (IEA,ISO)
endoplasmic reticulum calcium ion homeostasis  (IEA,ISO,ISS)
epithelial cell proliferation  (IEA,ISO)
forebrain development  (IEA,ISO)
gene expression  (IEA,ISO)
heart development  (IEA,ISO)
heart looping  (IEA,ISO)
hematopoietic progenitor cell differentiation  (IEA,ISO)
intracellular calcium ion homeostasis  (IEA,ISO)
intracellular signal transduction  (IEA)
L-glutamate import across plasma membrane  (IEA,ISO)
learning or memory  (IEA,ISO)
locomotion  (IEA,ISO)
membrane protein ectodomain proteolysis  (IBA,IEA,ISO,ISS)
memory  (IEA,ISO)
mitochondrial transport  (IEA,ISO)
myeloid dendritic cell differentiation  (IEA,ISO)
myeloid leukocyte differentiation  (IEA,ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of apoptotic signaling pathway  (IEA,ISO)
negative regulation of axonogenesis  (IEA,ISO)
negative regulation of epidermal growth factor-activated receptor activity  (ISO)
negative regulation of gene expression  (IEA)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of transcription by RNA polymerase II  (IEA)
negative regulation of ubiquitin-dependent protein catabolic process  (IEA)
negative regulation of ubiquitin-protein transferase activity  (ISO)
neural retina development  (ISO)
neurogenesis  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
neuron cellular homeostasis  (IEA,ISO)
neuron development  (IEA,ISO)
neuron differentiation  (IEA,ISO)
neuron migration  (IEA,ISO)
neuron projection maintenance  (IEA)
Notch receptor processing  (IEA,ISO)
Notch signaling pathway  (IBA,IEA,ISO)
positive regulation of amyloid fibril formation  (IEA)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of coagulation  (IEA,ISO)
positive regulation of dendritic spine development  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of gene expression  (IEA)
positive regulation of glycolytic process  (IEA)
positive regulation of L-glutamate import across plasma membrane  (IEA,ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (IEA)
positive regulation of protein import into nucleus  (IEA)
positive regulation of protein kinase activity  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of receptor recycling  (IEA)
positive regulation of tumor necrosis factor production  (IEA)
post-embryonic development  (IEA,ISO)
protein catabolic process at postsynapse  (IEA)
protein glycosylation  (IEA,ISO)
protein maturation  (IEA,ISO)
protein processing  (IBA,IEA,ISO,ISS)
protein transport  (IEA,ISO)
proteolysis  (IEA)
regulation of canonical Wnt signaling pathway  (IEA,ISS)
regulation of epidermal growth factor-activated receptor activity  (ISO)
regulation of gene expression  (IEA)
regulation of neuron projection development  (IEA,ISS)
regulation of phosphorylation  (ISO)
regulation of postsynapse organization  (IEA)
regulation of resting membrane potential  (IEA,ISO)
regulation of synaptic plasticity  (IEA,ISO)
regulation of synaptic transmission, glutamatergic  (IEA,ISO)
regulation of synaptic vesicle cycle  (IEA)
response to oxidative stress  (IEA,ISO)
segmentation  (IEA,ISO)
sequestering of calcium ion  (IEA,ISO)
skeletal system morphogenesis  (IEA,ISO)
skin morphogenesis  (IEA)
smooth endoplasmic reticulum calcium ion homeostasis  (IEA,ISO)
somitogenesis  (IEA,ISO)
synapse organization  (IEA)
synaptic vesicle targeting  (IEA,ISO)
T cell activation involved in immune response  (IEA,ISO)
T cell receptor signaling pathway  (IEA,ISO)
thymus development  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:20875843   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PSEN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1846,495,551 - 46,569,532 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl846,495,624 - 46,569,532 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,188,004 - 46,253,311 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0846,719,986 - 46,800,157 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl846,720,051 - 46,800,135 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,399,068 - 46,464,638 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,414,872 - 46,480,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0846,805,794 - 46,871,397 (+)NCBIUU_Cfam_GSD_1.0
PSEN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,136,417 - 73,223,691 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,136,418 - 73,223,691 (+)EnsemblGRCh38hg38GRCh38
GRCh371473,603,215 - 73,690,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361472,672,932 - 72,756,862 (+)NCBINCBI36Build 36hg18NCBI36
Build 341472,684,480 - 72,755,750NCBI
Celera1453,666,429 - 53,753,632 (+)NCBICelera
Cytogenetic Map14q24.2NCBI
HuRef1453,768,824 - 53,855,913 (+)NCBIHuRef
CHM1_11473,542,049 - 73,629,540 (+)NCBICHM1_1
T2T-CHM13v2.01467,341,963 - 67,429,152 (+)NCBIT2T-CHM13v2.0
Psen1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391283,734,926 - 83,781,869 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1283,734,926 - 83,781,973 (+)EnsemblGRCm39 Ensembl
GRCm381283,688,152 - 83,735,095 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1283,688,152 - 83,735,199 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,029,513 - 85,076,149 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361284,578,311 - 84,624,947 (+)NCBIMGSCv36mm8
Celera1285,135,054 - 85,181,689 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1238.84NCBI
Psen1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,054,160 - 109,106,191 (+)NCBIGRCr8
mRatBN7.26103,323,052 - 103,375,088 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,323,120 - 103,371,650 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6103,495,949 - 103,532,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06103,795,166 - 103,831,556 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,164,639 - 103,201,021 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,169,514 - 107,221,000 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,169,528 - 107,216,798 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06118,324,910 - 118,373,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46107,737,543 - 107,776,357 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16107,729,188 - 107,781,021 (+)NCBI
Celera6101,163,513 - 101,199,486 (+)NCBICelera
Cytogenetic Map6q31NCBI
Psen1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555232,128,529 - 2,210,737 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555232,128,529 - 2,210,737 (-)NCBIChiLan1.0ChiLan1.0
PSEN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,248,985 - 74,330,085 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11473,465,369 - 73,549,888 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01453,718,299 - 53,802,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11472,579,024 - 72,663,876 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1472,579,024 - 72,663,876 (+)Ensemblpanpan1.1panPan2
Psen1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864029,540,161 - 29,604,355 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364882,464,527 - 2,530,065 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364882,464,623 - 2,528,807 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSEN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl796,478,190 - 96,569,130 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1796,478,179 - 96,567,884 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,265,830 - 102,360,301 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q12-q26NCBI
PSEN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12450,394,310 - 50,476,521 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2450,405,590 - 50,472,132 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605338,577,780 - 38,659,678 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psen1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473428,200,140 - 28,272,743 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473428,200,358 - 28,272,684 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PSEN1
804 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001002943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001293284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005623169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005623170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014115643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014115644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038672834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY498704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY498705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY926590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000026626   ⟹   ENSCAFP00000024732
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl846,506,229 - 46,569,532 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000036386   ⟹   ENSCAFP00000031755
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl846,495,624 - 46,568,483 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000064018   ⟹   ENSCAFP00000047422
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl846,506,229 - 46,569,532 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000072273   ⟹   ENSCAFP00000056188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl846,495,624 - 46,530,696 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845021689   ⟹   ENSCAFP00845017053
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl846,720,051 - 46,800,135 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845021711   ⟹   ENSCAFP00845017072
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl846,720,051 - 46,800,135 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845021911   ⟹   ENSCAFP00845017231
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl846,720,051 - 46,755,619 (+)Ensembl
RefSeq Acc Id: NM_001002943   ⟹   NP_001002943
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1846,506,229 - 46,569,532 (+)NCBI
Dog10K_Boxer_Tasha846,188,004 - 46,253,311 (+)NCBI
ROS_Cfam_1.0846,731,142 - 46,797,044 (+)NCBI
UMICH_Zoey_3.1846,399,068 - 46,464,638 (+)NCBI
UNSW_CanFamBas_1.0846,414,872 - 46,480,438 (+)NCBI
UU_Cfam_GSD_1.0846,805,794 - 46,871,397 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001293284   ⟹   NP_001280213
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1846,506,229 - 46,569,532 (+)NCBI
Dog10K_Boxer_Tasha846,188,004 - 46,253,311 (+)NCBI
ROS_Cfam_1.0846,731,142 - 46,797,044 (+)NCBI
UMICH_Zoey_3.1846,399,068 - 46,464,638 (+)NCBI
UNSW_CanFamBas_1.0846,414,872 - 46,480,438 (+)NCBI
UU_Cfam_GSD_1.0846,805,794 - 46,871,397 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038672831   ⟹   XP_038528759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0846,719,986 - 46,800,157 (+)NCBI
RefSeq Acc Id: XM_038672832   ⟹   XP_038528760
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0846,719,994 - 46,800,157 (+)NCBI
RefSeq Acc Id: XM_038672833   ⟹   XP_038528761
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0846,720,190 - 46,800,157 (+)NCBI
RefSeq Acc Id: XM_038672834   ⟹   XP_038528762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0846,719,986 - 46,800,157 (+)NCBI
RefSeq Acc Id: NP_001002943   ⟸   NM_001002943
- Peptide Label: isoform 1
- UniProtKB: Q6RH32 (UniProtKB/Swiss-Prot),   Q6RH31 (UniProtKB/Swiss-Prot),   A0A8C0PFQ1 (UniProtKB/TrEMBL),   A0A8C0QV56 (UniProtKB/TrEMBL),   A0A8I3RZ86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001280213   ⟸   NM_001293284
- Peptide Label: isoform 2
- UniProtKB: Q6RH32 (UniProtKB/Swiss-Prot),   Q6RH31 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSCAFP00000047422   ⟸   ENSCAFT00000064018
Ensembl Acc Id: ENSCAFP00000056188   ⟸   ENSCAFT00000072273
Ensembl Acc Id: ENSCAFP00000031755   ⟸   ENSCAFT00000036386
Ensembl Acc Id: ENSCAFP00000024732   ⟸   ENSCAFT00000026626
RefSeq Acc Id: XP_038528759   ⟸   XM_038672831
- Peptide Label: isoform X1
- UniProtKB: Q6RH32 (UniProtKB/Swiss-Prot),   Q6RH31 (UniProtKB/Swiss-Prot),   A0A8C0PFQ1 (UniProtKB/TrEMBL),   A0A8C0QV56 (UniProtKB/TrEMBL),   A0A8I3RZ86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038528762   ⟸   XM_038672834
- Peptide Label: isoform X2
- UniProtKB: Q6RH32 (UniProtKB/Swiss-Prot),   Q6RH31 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038528760   ⟸   XM_038672832
- Peptide Label: isoform X1
- UniProtKB: Q6RH32 (UniProtKB/Swiss-Prot),   Q6RH31 (UniProtKB/Swiss-Prot),   A0A8C0PFQ1 (UniProtKB/TrEMBL),   A0A8C0QV56 (UniProtKB/TrEMBL),   A0A8I3RZ86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038528761   ⟸   XM_038672833
- Peptide Label: isoform X1
- UniProtKB: Q6RH32 (UniProtKB/Swiss-Prot),   Q6RH31 (UniProtKB/Swiss-Prot),   A0A8C0PFQ1 (UniProtKB/TrEMBL),   A0A8C0QV56 (UniProtKB/TrEMBL),   A0A8I3RZ86 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845017231   ⟸   ENSCAFT00845021911
Ensembl Acc Id: ENSCAFP00845017053   ⟸   ENSCAFT00845021689
Ensembl Acc Id: ENSCAFP00845017072   ⟸   ENSCAFT00845021711


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016815 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030023358 UniProtKB/TrEMBL
  ENSCAFG00040008031 UniProtKB/TrEMBL
  ENSCAFG00845012166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026626.3 UniProtKB/TrEMBL
  ENSCAFT00030042968.1 UniProtKB/TrEMBL
  ENSCAFT00030043061.1 UniProtKB/TrEMBL
  ENSCAFT00030043099.1 UniProtKB/TrEMBL
  ENSCAFT00030043141.1 UniProtKB/TrEMBL
  ENSCAFT00040015096.1 UniProtKB/TrEMBL
  ENSCAFT00040015133.1 UniProtKB/TrEMBL
  ENSCAFT00040015180.1 UniProtKB/TrEMBL
  ENSCAFT00845021689 ENTREZGENE
  ENSCAFT00845021689.1 UniProtKB/TrEMBL
  ENSCAFT00845021711.1 UniProtKB/TrEMBL
  ENSCAFT00845021911.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.472.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Pept_A22A_PS1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_A22A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Preselin/SPP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Presenilin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403408 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene PSEN1 ENTREZGENE
PANTHER PRESENILIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10202 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Presenilin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRESENILIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRESENILIN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0P9B7_CANLF UniProtKB/TrEMBL
  A0A8C0PFH5_CANLF UniProtKB/TrEMBL
  A0A8C0PFQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PNH0_CANLF UniProtKB/TrEMBL
  A0A8C0QFM1_CANLF UniProtKB/TrEMBL
  A0A8C0QV56 ENTREZGENE
  A0A8I3NLP9_CANLF UniProtKB/TrEMBL
  A0A8I3NM41_CANLF UniProtKB/TrEMBL
  A0A8I3RZ86 ENTREZGENE, UniProtKB/TrEMBL
  PSN1_CANLF UniProtKB/Swiss-Prot
  Q56JJ5_CANLF UniProtKB/TrEMBL
  Q6RH31 ENTREZGENE
  Q6RH32 ENTREZGENE
UniProt Secondary Q6RH32 UniProtKB/Swiss-Prot
VGNC ID VGNC:45085 ENTREZGENE