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Gene: SUV39H1 (suppressor of variegation 3-9 homolog 1) Homo sapiens
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Symbol: SUV39H1
Name: suppressor of variegation 3-9 homolog 1
Description: Exhibits histone methyltransferase activity (H3-K9 specific) and protein N-terminus binding activity. Involved in cellular response to DNA damage stimulus; cellular response to hypoxia; and negative regulation of transcription, DNA-templated. Localizes to the chromatin silencing complex and rDNA heterochromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H3-K9-HMTase 1; histone H3-K9 methyltransferase 1; histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; lysine N-methyltransferase 1A; MG44; position-effect variegation 3-9 homolog; Su(var)3-9 homolog 1; SUV39H
Orthologs:
Mus musculus (house mouse) : Suv39h1 (suppressor of variegation 3-9 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Suv39h1 (suppressor of variegation 3-9 homolog 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Suv39h1 (suppressor of variegation 3-9 homolog 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SUV39H1 (suppressor of variegation 3-9 homolog 1)
Canis lupus familiaris (dog) : SUV39H1 (suppressor of variegation 3-9 homolog 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Suv39h1 (suppressor of variegation 3-9 homolog 1)
Sus scrofa (pig) : SUV39H1 (suppressor of variegation 3-9 homolog 1)
Chlorocebus sabaeus (green monkey) : SUV39H1 (suppressor of variegation 3-9 homolog 1)
Heterocephalus glaber (naked mole-rat) : Suv39h1 (suppressor of variegation 3-9 homolog 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX48,695,554 - 48,709,012 (+)Ensembl
GRCh38X48,695,554 - 48,709,016 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,553,945 - 48,567,407 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,440,075 - 48,452,351 (+)NCBINCBI36hg18NCBI36
Build 34X48,311,380 - 48,323,651NCBI
CeleraX53,096,600 - 53,108,876 (-)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,217,119 - 46,229,438 (+)NCBIHuRef
CHM1_1X48,585,113 - 48,598,575 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SUV39H1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348120
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.