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Gene: HAX1 (HCLS1 associated protein X-1) Homo sapiens
Symbol: HAX1
Name: HCLS1 associated protein X-1
Description: Exhibits interleukin-1 binding activity and protein N-terminus binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of actin cytoskeleton organization. Localizes to the mitochondrial intermembrane space; mitochondrial outer membrane; and transcription factor complex. Implicated in severe congenital neutropenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ17042; FLJ18492; FLJ93803; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HSP1BP-1; SCN3
Mus musculus (house mouse) : Hax1 (HCLS1 associated X-1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hax1 (HCLS1 associated protein X-1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hax1 (HCLS1 associated protein X-1)
Pan paniscus (bonobo/pygmy chimpanzee) : HAX1 (HCLS1 associated protein X-1)
Canis lupus familiaris (dog) : HAX1 (HCLS1 associated protein X-1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hax1 (HCLS1 associated protein X-1)
Sus scrofa (pig) : HAX1 (HCLS1 associated protein X-1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381154,272,629 - 154,275,875 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371154,245,039 - 154,248,351 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,511,663 - 152,514,975 (+)NCBINCBI36hg18NCBI36
Celera1127,316,760 - 127,320,072 (+)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1125,608,714 - 125,612,284 (+)NCBIHuRef
CHM1_11155,641,372 - 155,644,684 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HAX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607073
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.