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Gene: HAX1 (HCLS1 associated protein X-1) Homo sapiens
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Symbol: HAX1
Name: HCLS1 associated protein X-1
Description: Exhibits interleukin-1 binding activity and protein N-terminus binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of actin cytoskeleton organization. Localizes to the mitochondrial intermembrane space; mitochondrial outer membrane; and transcription factor complex. Implicated in severe congenital neutropenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ17042; FLJ18492; FLJ93803; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HSP1BP-1; SCN3
Orthologs:
Mus musculus (house mouse) : Hax1 (HCLS1 associated X-1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hax1 (HCLS1 associated protein X-1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hax1 (HCLS1 associated protein X-1)
Pan paniscus (bonobo/pygmy chimpanzee) : HAX1 (HCLS1 associated protein X-1)
Canis lupus familiaris (dog) : HAX1 (HCLS1 associated protein X-1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hax1 (HCLS1 associated protein X-1)
Sus scrofa (pig) : HAX1 (HCLS1 associated protein X-1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,272,629 - 154,275,875 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371154,245,039 - 154,248,351 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,511,663 - 152,514,975 (+)NCBINCBI36hg18NCBI36
Celera1127,316,760 - 127,320,072 (+)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1125,608,714 - 125,612,284 (+)NCBIHuRef
CHM1_11155,641,372 - 155,644,684 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HAX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607073
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.