(+)-schisandrin B multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ERN1 mRNA] CTD PMID:31150632 (S)-nicotine multiple interactions ISO Ern1 (Mus musculus) 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 (Z)-3-butylidenephthalide increases expression EXP 6480464 butylidenephthalide results in increased expression of ERN1 protein CTD PMID:23770345 1,2-dichloroethane decreases expression ISO Ern1 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of ERN1 mRNA CTD PMID:28973639 1,2-dichloroethane increases expression ISO Ern1 (Mus musculus) 6480464 ethylene dichloride results in increased expression of ERN1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO Ern1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of ERN1 mRNA CTD PMID:22206623 1,4-dithiothreitol multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Dithiothreitol results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 1,4-dithiothreitol increases expression EXP 6480464 Dithiothreitol results in increased expression of ERN1 protein CTD PMID:25321315 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine multiple interactions ISO Ern1 (Mus musculus) 6480464 1-(2-(3 and 4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of ERN1 protein modified form]] CTD PMID:30661753 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Ern1 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 and PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 TXN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Ern1 (Mus musculus) 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-naphthyl isothiocyanate multiple interactions EXP 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of ERN1 mRNA CTD PMID:27344345 15-acetyldeoxynivalenol decreases expression EXP 6480464 15-acetyldeoxynivalenol results in decreased expression of ERN1 mRNA CTD PMID:20682335 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of ERN1 mRNA CTD PMID:23373633 and PMID:31614463 17beta-estradiol affects expression ISO Ern1 (Rattus norvegicus) 6480464 Estradiol affects the expression of ERN1 mRNA CTD PMID:32145629 17beta-hydroxy-5alpha-androstan-3-one increases expression EXP 6480464 Dihydrotestosterone results in increased expression of ERN1 mRNA CTD PMID:29581250 1H-pyrazole increases expression ISO Ern1 (Mus musculus) 6480464 pyrazole results in increased expression of ERN1 mRNA CTD PMID:17945193 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 ERN1 protein affects the reaction [2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO Ern1 (Mus musculus) 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether affects response to substance EXP 6480464 ERN1 protein affects the susceptibility to 2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether increases phosphorylation ISO Ern1 (Mus musculus) 6480464 2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:22543052 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ern1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of ERN1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ern1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ERN1 mRNA CTD PMID:18796159 and PMID:27136898 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ern1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ERN1 mRNA CTD PMID:18796159 and PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of ERN1 protein CTD PMID:24932542 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ern1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ERN1 mRNA CTD PMID:21570461 2,4-dichlorophenol increases expression ISO Ern1 (Mus musculus) 6480464 2 and 4-dichlorophenol results in increased expression of ERN1 mRNA CTD PMID:25160872 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO Ern1 (Mus musculus) 6480464 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] and ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine results in increased expression of ERN1 mRNA CTD PMID:33812996 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] CTD PMID:33812996 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of ERN1 mRNA CTD PMID:30851411 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 3,3',5,5'-tetrabromobisphenol A increases expression ISO Ern1 (Mus musculus) 6480464 tetrabromobisphenol A results in increased expression of ERN1 mRNA CTD PMID:25172293 3,4-methylenedioxymethamphetamine decreases expression ISO Ern1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ERN1 mRNA CTD PMID:26251327 3-acetyldeoxynivalenol increases expression EXP 6480464 3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA CTD PMID:20682335 3-acetyldeoxynivalenol multiple interactions ISO Ern1 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA] CTD PMID:35413383 3-acetyldeoxynivalenol increases expression ISO Ern1 (Mus musculus) 6480464 3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA CTD PMID:35413383 3-chloropropane-1,2-diol increases expression ISO Ern1 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of ERN1 mRNA CTD PMID:28522335 3-chloropropane-1,2-diol multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein] and alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:33651226 3-chloropropane-1,2-diol multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein] and alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:33651226 3H-1,2-dithiole-3-thione decreases expression ISO Ern1 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of ERN1 mRNA CTD PMID:19162173 4-hydroxynon-2-enal decreases expression ISO Ern1 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of ERN1 mRNA CTD PMID:19191707 4-nitrophenol decreases expression ISO Ern1 (Mus musculus) 6480464 4-nitrophenol results in decreased expression of ERN1 mRNA CTD PMID:34673133 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein] more ... CTD PMID:23885834 more ... 4-phenylbutyric acid multiple interactions ISO Ern1 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA] more ... CTD PMID:35413383 more ... 4-phenylbutyric acid decreases expression EXP 6480464 4-phenylbutyric acid results in decreased expression of ERN1 protein CTD PMID:29444456 more ... 4-phenylbutyric acid increases expression EXP 6480464 4-phenylbutyric acid results in increased expression of ERN1 protein CTD PMID:33651226 4-phenylbutyric acid multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein] and 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] CTD PMID:20399799 and PMID:33651226 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of ERN1 mRNA CTD PMID:32535746 6-propyl-2-thiouracil decreases expression ISO Ern1 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of ERN1 mRNA CTD PMID:30047161 abamectin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of ERN1 mRNA] CTD PMID:34748272 abamectin increases expression ISO Ern1 (Rattus norvegicus) 6480464 abamectin results in increased expression of ERN1 mRNA CTD PMID:34748272 acetamide decreases expression ISO Ern1 (Rattus norvegicus) 6480464 acetamide results in decreased expression of ERN1 mRNA CTD PMID:31881176 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of ERN1 mRNA CTD PMID:32763439 ADP multiple interactions ISO Ern1 (Mus musculus) 6480464 Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein] CTD PMID:25164867 ADP decreases activity ISO Ern1 (Mus musculus) 6480464 Adenosine Diphosphate results in decreased activity of ERN1 protein CTD PMID:25164867 aflatoxin B1 increases expression ISO Ern1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of ERN1 mRNA CTD PMID:19770486 agomelatine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 agomelatine inhibits the reaction [Dietary Fats results in increased phosphorylation of ERN1 protein] and agomelatine inhibits the reaction [Galactose results in increased phosphorylation of ERN1 protein] CTD PMID:34081941 and PMID:34673010 aldehydo-D-glucosamine multiple interactions ISO Ern1 (Mus musculus) 6480464 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] and ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 aldehydo-D-glucosamine multiple interactions EXP 6480464 NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] CTD PMID:33812996 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of ERN1 mRNA CTD PMID:33812996 aldehydo-D-glucose increases phosphorylation EXP 6480464 Glucose deficiency results in increased phosphorylation of ERN1 protein CTD PMID:31022492 aldehydo-D-glucose multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] and Metformin inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] CTD PMID:34801538 aldehydo-D-glucose increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Glucose results in increased phosphorylation of ERN1 protein CTD PMID:34801538 aldehydo-D-glucose multiple interactions EXP 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein] more ... CTD PMID:31022492 and PMID:35961541 all-trans-retinoic acid increases expression ISO Ern1 (Mus musculus) 6480464 Tretinoin results in increased expression of ERN1 mRNA and Tretinoin results in increased expression of ERN1 protein CTD PMID:22498432 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of ERN1 mRNA CTD PMID:23724009 allopurinol increases expression EXP 6480464 Allopurinol results in increased expression of ERN1 mRNA CTD PMID:32535746 alpha-D-galactose multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 agomelatine inhibits the reaction [Galactose results in increased phosphorylation of ERN1 protein] CTD PMID:34673010 alpha-D-galactose increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Galactose results in increased phosphorylation of ERN1 protein CTD PMID:34673010 amiloride multiple interactions ISO Ern1 (Mus musculus) 6480464 Amiloride inhibits the reaction [Tunicamycin results in increased phosphorylation of and results in increased activity of ERN1 protein] CTD PMID:20015086 amiodarone increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:28962527 and PMID:34259586 amiodarone increases phosphorylation EXP 6480464 Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:32651653 amosite asbestos increases expression EXP 6480464 Asbestos more ... CTD PMID:23885834 amosite asbestos multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Asbestos more ... CTD PMID:23885834 amosite asbestos increases expression ISO Ern1 (Rattus norvegicus) 6480464 Asbestos and Amosite results in increased expression of ERN1 protein CTD PMID:23885834 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [dihydrocapsaicin results in increased expression of ERN1 protein] CTD PMID:19139269 apigenin multiple interactions ISO Ern1 (Mus musculus) 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein] and Apigenin inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] CTD PMID:20493918 aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of ERN1 mRNA CTD PMID:33212167 arsenite(3-) multiple interactions EXP 6480464 arsenite inhibits the reaction [G3BP1 protein binds to ERN1 mRNA] CTD PMID:32406909 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of ERN1 mRNA and Arsenic Trioxide results in increased expression of ERN1 protein CTD PMID:17963750 more ... arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of ERN1 protein CTD PMID:34560123 arsenous acid multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] CTD PMID:30660605 arsenous acid increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased phosphorylation of ERN1 protein CTD PMID:30660605 atrazine increases expression EXP 6480464 Atrazine results in increased expression of ERN1 mRNA CTD PMID:22378314 aucubin multiple interactions ISO Ern1 (Mus musculus) 6480464 aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein] CTD PMID:35961541 aucubin multiple interactions EXP 6480464 aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased phosphorylation of ERN1 protein] CTD PMID:35961541 Azaspiracid decreases expression EXP 6480464 azaspiracid results in decreased expression of ERN1 mRNA CTD PMID:28939011 baicalin multiple interactions ISO Ern1 (Mus musculus) 6480464 baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 benomyl multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein] and MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ERN1 protein] CTD PMID:27784618 benomyl increases expression EXP 6480464 Benomyl results in increased expression of ERN1 protein CTD PMID:27784618 benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of ERN1 promoter CTD PMID:27901495 benzo[a]pyrene diol epoxide I increases expression EXP 6480464 7 more ... CTD PMID:19150397 beta-D-glucosamine multiple interactions ISO Ern1 (Mus musculus) 6480464 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] and ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 beta-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of ERN1 mRNA CTD PMID:33812996 beta-D-glucosamine multiple interactions EXP 6480464 NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] CTD PMID:33812996 bicuculline multiple interactions ISO Ern1 (Mus musculus) 6480464 [Bicuculline co-treated with Ethanol] results in increased phosphorylation of ERN1 protein CTD PMID:29044621 bis(2-ethylhexyl) phthalate decreases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased phosphorylation of ERN1 protein CTD PMID:37692514 bis(2-ethylhexyl) phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 bisphenol A decreases expression ISO Ern1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of ERN1 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 bisphenol A increases expression ISO Ern1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of ERN1 mRNA CTD PMID:35699857 bisphenol A multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ERN1 mRNA] CTD PMID:35699857 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of ERN1 gene CTD PMID:31601247 bisphenol A affects expression ISO Ern1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of ERN1 mRNA CTD PMID:32145629 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ERN1 mRNA CTD PMID:30903817 bisphenol A increases methylation ISO Ern1 (Mus musculus) 6480464 bisphenol A results in increased methylation of ERN1 promoter CTD PMID:27312807 bortezomib multiple interactions EXP 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of ERN1 mRNA and Bortezomib affects the reaction [ricolinostat affects the phosphorylation of ERN1 protein] CTD PMID:22262760 and PMID:25522274 bortezomib decreases response to substance EXP 6480464 ERN1 results in decreased susceptibility to Bortezomib CTD PMID:16357177 brefeldin A multiple interactions ISO Ern1 (Mus musculus) 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein] CTD PMID:20493918 brefeldin A increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Brefeldin A results in increased phosphorylation of ERN1 protein CTD PMID:20493918 Butylbenzyl phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 Butylparaben increases expression EXP 6480464 butylparaben results in increased expression of ERN1 protein CTD PMID:29319206 butyric acid multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Butyric Acid results in increased expression of ERN1 protein] and Plicamycin inhibits the reaction [Butyric Acid results in increased expression of ERN1 protein] CTD PMID:26784903 butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of ERN1 protein CTD PMID:26784903 C.I. Natural Red 20 multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 shikonin inhibits the reaction [Glutamic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:35028790 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of ERN1 mRNA CTD PMID:21120746 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein and Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein] CTD PMID:34687772 cadmium atom multiple interactions ISO Ern1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ERN1 protein more ... CTD PMID:29373603 and PMID:37261864 cadmium dichloride multiple interactions ISO Ern1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ERN1 protein more ... CTD PMID:29373603 and PMID:37261864 cadmium dichloride increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Cadmium Chloride results in increased phosphorylation of ERN1 protein CTD PMID:36731763 cadmium dichloride increases expression ISO Ern1 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of ERN1 protein and Cadmium Chloride results in increased expression of ERN1 protein modified form CTD PMID:33813002 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of ERN1 mRNA and Cadmium Chloride results in increased expression of ERN1 protein CTD PMID:29444456 more ... cadmium dichloride multiple interactions EXP 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] more ... CTD PMID:29444456 more ... caffeine multiple interactions ISO Ern1 (Mus musculus) 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Calcimycin increases expression EXP 6480464 Calcimycin results in increased expression of ERN1 protein CTD PMID:19139269 calix[6]arene increases expression EXP 6480464 calix(6)arene results in increased expression of ERN1 protein CTD PMID:23872419 Candesartan cilexetil decreases expression ISO Ern1 (Rattus norvegicus) 6480464 candesartan cilexetil results in decreased expression of ERN1 protein CTD PMID:22120037 cannabidiol decreases expression ISO Ern1 (Mus musculus) 6480464 Cannabidiol results in decreased expression of ERN1 mRNA CTD PMID:33019509 cannabidiol increases phosphorylation EXP 6480464 Cannabidiol results in increased phosphorylation of ERN1 protein CTD PMID:31699976 cannabigerol decreases expression ISO Ern1 (Mus musculus) 6480464 cannabigerol results in decreased expression of ERN1 mRNA CTD PMID:33019509 cantharidin increases expression EXP 6480464 Cantharidin results in increased expression of ERN1 protein CTD PMID:27113412 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of ERN1 protein CTD PMID:19139269 and PMID:19699254 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of ERN1 mRNA CTD PMID:24752500 carbon nanotube increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Nanotubes and Carbon results in increased phosphorylation of ERN1 protein CTD PMID:24929217 carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of ERN1 mRNA CTD PMID:32493873 cerulenin multiple interactions EXP 6480464 Cerulenin affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] CTD PMID:17283163 ceruletide multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Dietary Fats promotes the reaction [Ceruletide results in increased expression of ERN1 mRNA] more ... CTD PMID:26873426 ceruletide increases expression ISO Ern1 (Rattus norvegicus) 6480464 Ceruletide results in increased expression of ERN1 mRNA and Ceruletide results in increased expression of ERN1 protein CTD PMID:26873426 CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to ERN1 gene] CTD PMID:28238834 chloroacetic acid multiple interactions ISO Ern1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of ERN1 protein] CTD PMID:25451595 chloroacetic acid increases phosphorylation ISO Ern1 (Mus musculus) 6480464 chloroacetic acid results in increased phosphorylation of ERN1 protein CTD PMID:25451595 chlorogenic acid multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein] and Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] CTD PMID:34801538 chloropicrin increases expression EXP 6480464 chloropicrin results in increased expression of ERN1 protein CTD PMID:22516760 choline multiple interactions ISO Ern1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene CTD PMID:20938992 chrysophanol increases expression EXP 6480464 chrysophanic acid results in increased expression of ERN1 protein CTD PMID:30300626 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ERN1 mRNA CTD PMID:27594783 cisplatin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 isoliquiritigenin inhibits the reaction [Cisplatin results in increased expression of ERN1 mRNA] CTD PMID:37561086 cisplatin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of ERN1 mRNA CTD PMID:37561086 clotrimazole decreases expression ISO Ern1 (Rattus norvegicus) 6480464 Clotrimazole results in decreased expression of ERN1 mRNA CTD PMID:30047161 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of ERN1 mRNA CTD PMID:19320972 cocaine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein] more ... CTD PMID:17303341 cocaine increases expression ISO Ern1 (Rattus norvegicus) 6480464 Cocaine results in increased expression of ERN1 protein CTD PMID:17303341 copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of ERN1 mRNA CTD PMID:30911355 copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of ERN1 mRNA CTD PMID:30911355 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of ERN1 mRNA CTD PMID:19549813 cordycepin decreases expression ISO Ern1 (Mus musculus) 6480464 cordycepin results in decreased expression of ERN1 protein CTD PMID:31145545 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of ERN1 mRNA CTD PMID:17999991 curcumin increases expression EXP 6480464 Curcumin results in increased expression of ERN1 mRNA CTD PMID:29723631 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Butyric Acid results in increased expression of ERN1 protein] CTD PMID:26784903 cyclophosphamide multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein] and Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein] CTD PMID:32197949 cyclophosphamide increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased phosphorylation of ERN1 protein CTD PMID:32197949 cyclosporin A increases expression ISO Ern1 (Rattus norvegicus) 6480464 Cyclosporine results in increased expression of ERN1 protein CTD PMID:20136702 cyclosporin A increases phosphorylation EXP 6480464 Cyclosporine results in increased phosphorylation of ERN1 protein CTD PMID:35033536 cyclosporin A multiple interactions ISO Ern1 (Mus musculus) 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of ERN1 protein] and TLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of ERN1 protein] CTD PMID:27585667 cyclosporin A increases expression ISO Ern1 (Mus musculus) 6480464 Cyclosporine results in increased expression of ERN1 protein CTD PMID:27585667 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of ERN1 mRNA CTD PMID:25562108 cyclosporin A increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Cyclosporine results in increased phosphorylation of ERN1 protein CTD PMID:23958496 cyclosporin A affects localization ISO Ern1 (Mus musculus) 6480464 Cyclosporine affects the localization of ERN1 protein CTD PMID:23958496 cyclosporin A multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Melatonin promotes the reaction [Cyclosporine results in increased expression of ERN1 protein] CTD PMID:20136702 cypermethrin increases expression ISO Ern1 (Rattus norvegicus) 6480464 cypermethrin results in increased expression of ERN1 mRNA CTD PMID:35876585 cypermethrin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [cypermethrin results in increased expression of ERN1 mRNA] CTD PMID:35876585 D-glucose multiple interactions EXP 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein] more ... CTD PMID:31022492 and PMID:35961541 D-glucose multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] and Metformin inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] CTD PMID:34801538 D-glucose increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Glucose results in increased phosphorylation of ERN1 protein CTD PMID:34801538 D-glucose increases phosphorylation EXP 6480464 Glucose deficiency results in increased phosphorylation of ERN1 protein CTD PMID:31022492 deguelin decreases expression EXP 6480464 deguelin results in decreased expression of ERN1 protein CTD PMID:25322282 demethoxycurcumin multiple interactions EXP 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] CTD PMID:26264395 deoxynivalenol decreases expression EXP 6480464 deoxynivalenol results in decreased expression of ERN1 mRNA CTD PMID:20682335 deoxynivalenol increases expression ISO Ern1 (Mus musculus) 6480464 deoxynivalenol results in increased expression of ERN1 protein CTD PMID:19336499 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 Di-n-octyl phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 diarsenic trioxide increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased phosphorylation of ERN1 protein CTD PMID:30660605 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of ERN1 protein CTD PMID:34560123 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of ERN1 mRNA and Arsenic Trioxide results in increased expression of ERN1 protein CTD PMID:17963750 more ... diarsenic trioxide multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] CTD PMID:30660605 dibutyl phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 diclofenac affects expression EXP 6480464 Diclofenac affects the expression of ERN1 mRNA CTD PMID:24752500 Didecyldimethylammonium increases expression EXP 6480464 didecyldimethylammonium results in increased expression of ERN1 mRNA CTD PMID:32763356 diethyl phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 dihydrocapsaicin multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [dihydrocapsaicin results in increased expression of ERN1 protein] CTD PMID:19139269 dihydrocapsaicin increases expression EXP 6480464 dihydrocapsaicin results in increased expression of ERN1 protein CTD PMID:19139269 Diisodecyl phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 diisononyl phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA and [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein CTD PMID:37364641 dimethylarsinous acid increases expression EXP 6480464 dimethylarsinous acid results in increased expression of ERN1 mRNA CTD PMID:23487506 Dinitramine increases expression ISO Ern1 (Mus musculus) 6480464 dinitramine results in increased expression of ERN1 protein CTD PMID:33288293 dinophysistoxin 1 increases expression EXP 6480464 dinophysistoxin 1 results in increased expression of ERN1 mRNA CTD PMID:28939011 dioxygen multiple interactions ISO Ern1 (Mus musculus) 6480464 1-(4-(6-bromobenzo(1 more ... CTD PMID:32996202 dioxygen increases expression ISO Ern1 (Mus musculus) 6480464 Oxygen results in increased expression of ERN1 protein CTD PMID:32996202 diuron decreases expression EXP 6480464 Diuron results in decreased expression of ERN1 mRNA CTD PMID:35967413 dizocilpine maleate multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 doxorubicin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Doxorubicin results in increased expression of ERN1 protein] CTD PMID:35152301 doxorubicin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of ERN1 protein CTD PMID:35152301 edaravone increases expression ISO Ern1 (Rattus norvegicus) 6480464 Edaravone results in increased expression of ERN1 mRNA CTD PMID:19558813 endosulfan increases expression ISO Ern1 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of ERN1 mRNA CTD PMID:29391264 endosulfan affects expression ISO Ern1 (Rattus norvegicus) 6480464 Endosulfan affects the expression of ERN1 mRNA CTD PMID:31464424 epoxiconazole decreases expression ISO Ern1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of ERN1 mRNA CTD PMID:35436446 epoxomicin multiple interactions ISO Ern1 (Mus musculus) 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 erastin multiple interactions ISO Ern1 (Mus musculus) 6480464 GW 506033X inhibits the reaction [erastin results in increased phosphorylation of ERN1 protein] CTD PMID:30817950 erastin increases phosphorylation ISO Ern1 (Mus musculus) 6480464 erastin results in increased phosphorylation of ERN1 protein CTD PMID:30817950 ethanol increases expression ISO Ern1 (Mus musculus) 6480464 Ethanol results in increased expression of ERN1 mRNA CTD PMID:30319688 ethanol increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Ethanol results in increased phosphorylation of ERN1 protein CTD PMID:29044621 ethanol multiple interactions ISO Ern1 (Mus musculus) 6480464 [Bicuculline co-treated with Ethanol] results in increased phosphorylation of ERN1 protein more ... CTD PMID:29044621 ethanol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of ERN1 protein modified form] CTD PMID:24224909 ethanol increases expression EXP 6480464 Ethanol results in increased expression of ERN1 protein modified form CTD PMID:24224909 ethanol decreases phosphorylation ISO Ern1 (Mus musculus) 6480464 Ethanol results in decreased phosphorylation of ERN1 protein CTD PMID:28119953 EUK-134 multiple interactions EXP 6480464 EUK-134 inhibits the reaction [Asbestos more ... CTD PMID:23885834 fentin chloride increases expression ISO Ern1 (Rattus norvegicus) 6480464 triphenyltin chloride results in increased expression of ERN1 protein CTD PMID:37156404 ferric ammonium citrate multiple interactions EXP 6480464 ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 ferric oxide multiple interactions ISO Ern1 (Mus musculus) 6480464 ferric oxide analog results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:25086211 flufenoxuron increases expression ISO Ern1 (Mus musculus) 6480464 flufenoxuron results in increased expression of ERN1 protein CTD PMID:33771252 fluoranthene multiple interactions ISO Ern1 (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of ERN1 mRNA CTD PMID:28329830 folic acid multiple interactions ISO Ern1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene CTD PMID:20938992 formaldehyde increases phosphorylation EXP 6480464 Formaldehyde results in increased phosphorylation of ERN1 protein CTD PMID:24140967 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of ERN1 mRNA CTD PMID:17938736 more ... fructose multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein and Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein] CTD PMID:34801538 fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of ERN1 gene CTD PMID:31601247 furan increases phosphorylation ISO Ern1 (Mus musculus) 6480464 furan results in increased phosphorylation of ERN1 protein CTD PMID:34450210 furan multiple interactions ISO Ern1 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased phosphorylation of ERN1 protein] CTD PMID:34450210 gadolinium trichloride multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein] CTD PMID:21198628 gadolinium trichloride increases expression ISO Ern1 (Rattus norvegicus) 6480464 gadolinium chloride results in increased expression of ERN1 protein CTD PMID:21198628 galactose multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 agomelatine inhibits the reaction [Galactose results in increased phosphorylation of ERN1 protein] CTD PMID:34673010 galactose increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Galactose results in increased phosphorylation of ERN1 protein CTD PMID:34673010 gamma-aminobutyric acid multiple interactions ISO Ern1 (Mus musculus) 6480464 gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased phosphorylation of ERN1 protein] CTD PMID:29044621 gentamycin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of ERN1 mRNA CTD PMID:33387578 geraniol multiple interactions EXP 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] CTD PMID:30141137 ginsenoside Rg1 multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of ERN1 protein] CTD PMID:30918470 glucose multiple interactions EXP 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein] more ... CTD PMID:31022492 and PMID:35961541 glucose increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Glucose results in increased phosphorylation of ERN1 protein CTD PMID:34801538 glucose multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] and Metformin inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] CTD PMID:34801538 glucose increases phosphorylation EXP 6480464 Glucose deficiency results in increased phosphorylation of ERN1 protein CTD PMID:31022492 glycyrrhetinate multiple interactions EXP 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 glycyrrhetinate multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ERN1 mRNA] CTD PMID:35699857 glycyrrhetinic acid multiple interactions EXP 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 glycyrrhetinic acid multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ERN1 mRNA] CTD PMID:35699857 glyphosate increases expression EXP 6480464 Glyphosate results in increased expression of ERN1 mRNA CTD PMID:31295307 gold atom increases phosphorylation EXP 6480464 Gold analog results in increased phosphorylation of ERN1 protein CTD PMID:26551149 gold(0) increases phosphorylation EXP 6480464 Gold analog results in increased phosphorylation of ERN1 protein CTD PMID:26551149 Guanabenz multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Guanabenz inhibits the reaction [Tunicamycin results in increased phosphorylation of ERN1 protein] CTD PMID:24892553 hesperidin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of ERN1 mRNA] more ... CTD PMID:34748272 more ... hexadecanoic acid multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 [Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 mRNA more ... CTD PMID:26873426 hexadecanoic acid increases expression ISO Ern1 (Mus musculus) 6480464 Palmitic Acid results in increased expression of ERN1 mRNA and Palmitic Acid results in increased expression of ERN1 protein CTD PMID:36030031 hexadecanoic acid multiple interactions EXP 6480464 3-N-1(spermine)-7 more ... CTD PMID:32283200 and PMID:32369900 hexadecanoic acid increases phosphorylation EXP 6480464 Palmitic Acid results in increased phosphorylation of ERN1 protein CTD PMID:32283200 hexadecanoic acid multiple interactions ISO Ern1 (Mus musculus) 6480464 4-phenylbutyric acid promotes the reaction [Palmitic Acid results in increased expression of ERN1 mRNA] more ... CTD PMID:29031535 more ... hexadecanoic acid increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Palmitic Acid results in increased phosphorylation of ERN1 protein CTD PMID:29031535 and PMID:29414781 homocysteine decreases phosphorylation EXP 6480464 Homocysteine results in decreased phosphorylation of ERN1 protein CTD PMID:22964297 hydrogen peroxide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ERN1 protein] CTD PMID:23885834 hydrogen peroxide increases expression ISO Ern1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of ERN1 protein CTD PMID:23885834 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of ERN1 protein CTD PMID:23885834 hydroquinone multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ERN1 protein] and 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ERN1 protein] CTD PMID:36646296 hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of ERN1 protein CTD PMID:36646296 hydroxychloroquine increases expression EXP 6480464 Hydroxychloroquine results in increased expression of ERN1 protein CTD PMID:25321315 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of ERN1 mRNA CTD PMID:32535746 indometacin multiple interactions EXP 6480464 Indomethacin results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:32535746 isoliquiritigenin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 isoliquiritigenin inhibits the reaction [Cisplatin results in increased expression of ERN1 mRNA] CTD PMID:37561086 L-1,4-dithiothreitol multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Dithiothreitol results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 L-1,4-dithiothreitol increases expression EXP 6480464 Dithiothreitol results in increased expression of ERN1 protein CTD PMID:25321315 L-glutamic acid multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 shikonin inhibits the reaction [Glutamic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:35028790 L-glutamic acid increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Glutamic Acid results in increased phosphorylation of ERN1 protein CTD PMID:35028790 L-methionine multiple interactions ISO Ern1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene CTD PMID:20938992 lead diacetate increases expression ISO Ern1 (Mus musculus) 6480464 lead acetate results in increased expression of ERN1 mRNA CTD PMID:21829687 lead diacetate increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 lead acetate results in increased phosphorylation of ERN1 protein CTD PMID:25088297 lead diacetate multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of ERN1 protein] CTD PMID:25088297 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of ERN1 mRNA CTD PMID:28988120 licoricidin increases expression EXP 6480464 licoricidin results in increased expression of ERN1 mRNA and licoricidin results in increased expression of ERN1 protein CTD PMID:37013980 linuron increases activity ISO Ern1 (Mus musculus) 6480464 Linuron results in increased activity of ERN1 protein CTD PMID:30661753 linuron multiple interactions EXP 6480464 Linuron promotes the reaction [ERN1 protein binds to SIGMAR1 protein] CTD PMID:30661753 linuron multiple interactions ISO Ern1 (Mus musculus) 6480464 1-(2-(3 and 4-dichlorophenyl)ethyl)-4-methylpiperazine inhibits the reaction [Linuron promotes the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of ERN1 protein modified form]] CTD PMID:30661753 lipopolysaccharide multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of ERN1 protein] CTD PMID:30918470 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of ERN1 protein CTD PMID:30918470 luteolin multiple interactions EXP 6480464 Luteolin inhibits the reaction [Thapsigargin results in increased expression of and results in increased phosphorylation of ERN1 protein] and Luteolin inhibits the reaction [Tunicamycin results in increased expression of and results in increased phosphorylation of ERN1 protein] CTD PMID:32407927 lycopene multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] CTD PMID:32544411 manganese(II) chloride multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein] CTD PMID:23934647 manganese(II) chloride increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 manganese chloride results in increased phosphorylation of ERN1 protein CTD PMID:23934647 and PMID:25732873 melatonin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form] and Melatonin promotes the reaction [Cyclosporine results in increased expression of ERN1 protein] CTD PMID:20136702 and PMID:28070110 metacetamol decreases expression ISO Ern1 (Mus musculus) 6480464 3-hydroxyacetanilide results in decreased expression of ERN1 mRNA CTD PMID:18544908 metformin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] CTD PMID:34801538 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [INS protein results in increased phosphorylation of ERN1 protein] CTD PMID:36764371 methamphetamine increases expression ISO Ern1 (Mus musculus) 6480464 Methamphetamine results in increased expression of ERN1 protein CTD PMID:27323860 methamphetamine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form] CTD PMID:28070110 methamphetamine increases expression ISO Ern1 (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of ERN1 protein modified form CTD PMID:28070110 methamphetamine multiple interactions EXP 6480464 ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein] more ... CTD PMID:27323860 methamphetamine increases phosphorylation EXP 6480464 Methamphetamine results in increased phosphorylation of ERN1 protein CTD PMID:27323860 methimazole decreases expression ISO Ern1 (Rattus norvegicus) 6480464 Methimazole results in decreased expression of ERN1 mRNA CTD PMID:30047161 methotrexate affects expression ISO Ern1 (Mus musculus) 6480464 Methotrexate affects the expression of ERN1 mRNA CTD PMID:18502557 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of ERN1 mRNA CTD PMID:34350509 methotrexate multiple interactions EXP 6480464 [Methotrexate co-treated with theaflavin-3 and 3'-digallate] results in decreased expression of ERN1 mRNA CTD PMID:34350509 methylmercury chloride multiple interactions ISO Ern1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form] and AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form] CTD PMID:31330229 methylmercury chloride increases expression ISO Ern1 (Mus musculus) 6480464 methylmercuric chloride results in increased expression of ERN1 protein modified form CTD PMID:31330229 methylparaben increases expression EXP 6480464 methylparaben results in increased expression of ERN1 mRNA CTD PMID:31745603 methyltestosterone multiple interactions EXP 6480464 [Methyltestosterone co-treated with Cholic Acids] affects the expression of ERN1 mRNA CTD PMID:27344345 microcystin-LR multiple interactions ISO Ern1 (Mus musculus) 6480464 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [cyanoginosin LR results in increased phosphorylation of ERN1 protein] more ... CTD PMID:33290805 microcystin-LR increases phosphorylation ISO Ern1 (Mus musculus) 6480464 cyanoginosin LR results in increased phosphorylation of ERN1 protein CTD PMID:33290805 minocycline increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Minocycline results in increased phosphorylation of ERN1 protein CTD PMID:22245251 mithramycin multiple interactions EXP 6480464 Plicamycin inhibits the reaction [Butyric Acid results in increased expression of ERN1 protein] CTD PMID:26784903 MK-2206 multiple interactions EXP 6480464 MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of ERN1 protein and mono-(2-ethylhexyl)phthalate results in increased expression of ERN1 protein modified form CTD PMID:36005737 mono(2-ethylhexyl) phthalate multiple interactions ISO Ern1 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein] and Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein] CTD PMID:37692514 mono(2-ethylhexyl) phthalate increases phosphorylation ISO Ern1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein CTD PMID:37692514 morusin increases expression EXP 6480464 morusin results in increased expression of ERN1 protein CTD PMID:29421517 muscimol multiple interactions ISO Ern1 (Mus musculus) 6480464 Muscimol inhibits the reaction [Ethanol results in increased phosphorylation of ERN1 protein] CTD PMID:29044621 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein] more ... CTD PMID:24394546 more ... N-acetyl-L-cysteine decreases phosphorylation EXP 6480464 Acetylcysteine results in decreased phosphorylation of ERN1 protein CTD PMID:34687772 N-acetyl-L-cysteine multiple interactions ISO Ern1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein] more ... CTD PMID:25451595 more ... N-acetyl-L-cysteine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein] more ... CTD PMID:21198628 and PMID:30633982 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ERN1 protein CTD PMID:19139269 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of ERN1 protein CTD PMID:27638906 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein] and ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein] CTD PMID:27638906 N-methyl-4-phenylpyridinium multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in increased activity of ERN1 protein and TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein] CTD PMID:12486162 and PMID:24140863 N-methyl-4-phenylpyridinium increases expression ISO Ern1 (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein CTD PMID:24140863 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein] CTD PMID:24140863 naltrexone multiple interactions EXP 6480464 Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein] CTD PMID:27323860 nicotine multiple interactions ISO Ern1 (Mus musculus) 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Nivalenol increases expression ISO Ern1 (Mus musculus) 6480464 nivalenol results in increased expression of ERN1 mRNA CTD PMID:35016910 Norbinaltorphimine multiple interactions EXP 6480464 norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein] CTD PMID:27323860 NORCANTHARIDIN increases expression EXP 6480464 norcantharidin results in increased expression of ERN1 protein CTD PMID:34272796 NORCANTHARIDIN multiple interactions EXP 6480464 Paclitaxel promotes the reaction [norcantharidin results in increased expression of ERN1 protein] CTD PMID:34272796 ochratoxin A multiple interactions EXP 6480464 Ursolic Acid inhibits the reaction [ochratoxin A results in increased expression of ERN1 protein] CTD PMID:36587836 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of ERN1 protein CTD PMID:36587836 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of ERN1 mRNA CTD PMID:28939011 oleic acid multiple interactions EXP 6480464 3-N-1(spermine)-7 more ... CTD PMID:32369900 orlistat multiple interactions EXP 6480464 orlistat affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] CTD PMID:17283163 oxaliplatin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Oxaliplatin results in increased expression of ERN1 mRNA CTD PMID:32544411 oxaliplatin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] CTD PMID:32544411 oxidopamine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Oxidopamine results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 paclitaxel increases expression ISO Ern1 (Rattus norvegicus) 6480464 Paclitaxel results in increased expression of ERN1 mRNA CTD PMID:36966900 paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of ERN1 protein CTD PMID:34272796 paclitaxel multiple interactions EXP 6480464 Paclitaxel promotes the reaction [norcantharidin results in increased expression of ERN1 protein] CTD PMID:34272796 paclitaxel multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Hesperidin inhibits the reaction [Paclitaxel results in increased expression of ERN1 mRNA] CTD PMID:36966900 paracetamol affects expression ISO Ern1 (Mus musculus) 6480464 Acetaminophen affects the expression of ERN1 mRNA CTD PMID:17562736 paracetamol increases expression ISO Ern1 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of ERN1 mRNA CTD PMID:33387578 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of ERN1 mRNA CTD PMID:21420995 and PMID:29067470 paracetamol increases expression ISO Ern1 (Mus musculus) 6480464 Acetaminophen results in increased expression of ERN1 mRNA CTD PMID:18544908 paraquat multiple interactions EXP 6480464 Paraquat promotes the reaction [MAP3K5 protein results in increased phosphorylation of ERN1 protein] CTD PMID:20929985 paraquat increases expression EXP 6480464 Paraquat results in increased expression of ERN1 mRNA and Paraquat results in increased expression of ERN1 protein modified form CTD PMID:28986289 and PMID:34097952 paraquat increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Paraquat results in increased phosphorylation of ERN1 protein CTD PMID:22245251 paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of ERN1 protein CTD PMID:20929985 and PMID:28986289 perfluorobutyric acid increases expression EXP 6480464 perfluorobutyric acid results in increased expression of ERN1 mRNA CTD PMID:36251517 perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of ERN1 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO Ern1 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in decreased expression of ERN1 mRNA CTD PMID:19162173 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ERN1 mRNA and perfluorooctanoic acid results in increased expression of ERN1 protein CTD PMID:26879310 and PMID:36251517 perfluorooctanoic acid increases expression ISO Ern1 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of ERN1 protein CTD PMID:37044272 perhexiline multiple interactions EXP 6480464 [perhexiline maleate results in increased abundance of Perhexiline] which results in increased expression of ERN1 mRNA and CYP2D6 protein inhibits the reaction [[perhexiline maleate results in increased abundance of Perhexiline] which results in increased expression of ERN1 mRNA] CTD PMID:36083301 pirinixic acid decreases expression ISO Ern1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of ERN1 mRNA CTD PMID:16985257 pirinixic acid decreases expression ISO Ern1 (Rattus norvegicus) 6480464 pirinixic acid results in decreased expression of ERN1 mRNA CTD PMID:19162173 poly(guanylic acid) multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 potassium iodide multiple interactions EXP 6480464 [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA and Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein] CTD PMID:24231001 pregnenolone 16alpha-carbonitrile increases expression ISO Ern1 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of ERN1 mRNA CTD PMID:19162173 proanthocyanidin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of ERN1 protein] CTD PMID:25088297 procymidone increases expression ISO Ern1 (Mus musculus) 6480464 procymidone results in increased expression of ERN1 mRNA and procymidone results in increased expression of ERN1 protein CTD PMID:35913088 propiconazole increases expression ISO Ern1 (Mus musculus) 6480464 propiconazole results in increased expression of ERN1 mRNA CTD PMID:21278054 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of ERN1 mRNA CTD PMID:28063906 quercetin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of ERN1 protein] more ... CTD PMID:26873426 more ... quercetin increases phosphorylation EXP 6480464 Quercetin results in increased phosphorylation of ERN1 protein CTD PMID:24612139 rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of ERN1 mRNA CTD PMID:30851411 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of ERN1 protein CTD PMID:24264887 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of ERN1 protein modified form] CTD PMID:24224909 rifampicin multiple interactions EXP 6480464 Rifampin results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:32535746 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of ERN1 mRNA CTD PMID:32535746 rotenone multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Rotenone results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 rotenone increases expression EXP 6480464 Rotenone results in increased expression of ERN1 protein CTD PMID:30141137 rotenone multiple interactions EXP 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] and MIR384 mRNA promotes the reaction [Rotenone results in increased phosphorylation of ERN1 protein] CTD PMID:26864693 and PMID:30141137 rotenone increases phosphorylation EXP 6480464 Rotenone results in increased phosphorylation of ERN1 protein CTD PMID:26864693 Salidroside multiple interactions ISO Ern1 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased phosphorylation of ERN1 protein] CTD PMID:34450210 SCH 23390 multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 sertraline increases expression EXP 6480464 Sertraline results in increased expression of ERN1 mRNA CTD PMID:24865413 Shikonin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 shikonin inhibits the reaction [Glutamic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:35028790 silicon dioxide multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 silicon dioxide increases expression ISO Ern1 (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of ERN1 protein CTD PMID:31028789 sincalide multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 [Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 mRNA more ... CTD PMID:26873426 sirolimus multiple interactions ISO Ern1 (Mus musculus) 6480464 [Sirolimus co-treated with HRAS protein] results in decreased expression of ERN1 protein and PPARD protein affects the reaction [[Sirolimus co-treated with HRAS protein] results in decreased expression of ERN1 protein] CTD PMID:24898257 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 sodium arsenite multiple interactions EXP 6480464 ERN1 affects the reaction [sodium arsenite results in increased expression of ACE mRNA] more ... CTD PMID:28973481 and PMID:32593899 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of ERN1 mRNA and sodium arsenite results in decreased expression of ERN1 protein CTD PMID:34032870 sodium arsenite increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 sodium arsenite results in increased phosphorylation of ERN1 protein CTD PMID:32593899 sodium arsenite increases expression ISO Ern1 (Mus musculus) 6480464 sodium arsenite results in increased expression of ERN1 protein CTD PMID:21911445 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ERN1 mRNA CTD PMID:28973481 sodium fluoride increases expression ISO Ern1 (Rattus norvegicus) 6480464 Sodium Fluoride results in increased expression of ERN1 mRNA and Sodium Fluoride results in increased expression of ERN1 protein CTD PMID:23707774 more ... sodium fluoride multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ERN1 mRNA] more ... CTD PMID:30633982 and PMID:35413380 sodium fluoride increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Sodium Fluoride results in increased phosphorylation of ERN1 protein CTD PMID:30633982 sodium fluoride multiple interactions EXP 6480464 [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA and Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein] CTD PMID:24231001 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of ERN1 mRNA and Sodium Fluoride results in increased expression of ERN1 protein CTD PMID:24231001 sodium fluoride increases expression ISO Ern1 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of ERN1 mRNA CTD PMID:21626649 streptozocin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] more ... CTD PMID:20399799 and PMID:34801538 streptozocin multiple interactions ISO Ern1 (Mus musculus) 6480464 [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein and aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein] CTD PMID:35961541 streptozocin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of ERN1 protein modified form CTD PMID:20399799 succimer multiple interactions ISO Ern1 (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ERN1 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ERN1 mRNA CTD PMID:21641980 and PMID:26378955 sulfadimethoxine decreases expression ISO Ern1 (Rattus norvegicus) 6480464 Sulfadimethoxine results in decreased expression of ERN1 mRNA CTD PMID:30047161 sulindac increases expression EXP 6480464 Sulindac results in increased expression of ERN1 mRNA CTD PMID:32535746 surfactin increases phosphorylation EXP 6480464 surfactin peptide results in increased phosphorylation of ERN1 protein CTD PMID:34850538 surfactin C increases phosphorylation EXP 6480464 surfactin peptide results in increased phosphorylation of ERN1 protein CTD PMID:34850538 T-2 toxin increases expression ISO Ern1 (Mus musculus) 6480464 T-2 Toxin results in increased expression of ERN1 protein CTD PMID:31170431 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of ERN1 protein CTD PMID:31170431 T-2 toxin multiple interactions EXP 6480464 ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein] and ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein] CTD PMID:31170431 tacrolimus hydrate increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Tacrolimus results in increased phosphorylation of ERN1 protein CTD PMID:23958496 taurine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] CTD PMID:30660605 tauroursodeoxycholic acid multiple interactions ISO Ern1 (Mus musculus) 6480464 ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 tert-butyl hydroperoxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]] more ... CTD PMID:24394546 tetrachloromethane increases activity ISO Ern1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased activity of ERN1 protein CTD PMID:25858767 tetrachloromethane multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ERN1 mRNA] CTD PMID:31150632 tetrachloromethane increases expression ISO Ern1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of ERN1 mRNA CTD PMID:31150632 tetrachloromethane increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased phosphorylation of ERN1 protein CTD PMID:25827057 and PMID:30538632 tetrachloromethane multiple interactions ISO Ern1 (Mus musculus) 6480464 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of ERN1 protein] CTD PMID:25827057 thapsigargin multiple interactions EXP 6480464 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] more ... CTD PMID:23576437 more ... thapsigargin increases phosphorylation EXP 6480464 Thapsigargin results in increased phosphorylation of ERN1 protein CTD PMID:23576437 more ... thapsigargin increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Thapsigargin results in increased phosphorylation of ERN1 protein CTD PMID:24638036 thapsigargin increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Thapsigargin results in increased phosphorylation of ERN1 protein CTD PMID:20493918 and PMID:23576437 thapsigargin affects splicing EXP 6480464 Thapsigargin affects the splicing of ERN1 mRNA CTD PMID:27587023 thapsigargin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Thapsigargin results in increased expression of ERN1 protein CTD PMID:23885834 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of ERN1 mRNA more ... CTD PMID:17963750 more ... thapsigargin multiple interactions ISO Ern1 (Mus musculus) 6480464 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] more ... CTD PMID:20493918 more ... Theaflavin 3,3'-digallate decreases expression EXP 6480464 theaflavin-3 and 3'-digallate results in decreased expression of ERN1 mRNA CTD PMID:34350509 Theaflavin 3,3'-digallate multiple interactions EXP 6480464 [Methotrexate co-treated with theaflavin-3 and 3'-digallate] results in decreased expression of ERN1 mRNA CTD PMID:34350509 thymoquinone increases expression EXP 6480464 thymoquinone results in increased expression of ERN1 mRNA and thymoquinone results in increased expression of ERN1 protein CTD PMID:29981725 titanium dioxide affects expression EXP 6480464 titanium dioxide affects the expression of ERN1 protein CTD PMID:30273564 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of ERN1 mRNA CTD PMID:30273564 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of ERN1 mRNA CTD PMID:21601586 trichloroethene increases expression ISO Ern1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of ERN1 mRNA CTD PMID:33387578 tris(2-butoxyethyl) phosphate affects expression EXP 6480464 tris(2-butoxyethyl) phosphate affects the expression of ERN1 mRNA CTD PMID:29024780 troglitazone decreases expression ISO Ern1 (Mus musculus) 6480464 troglitazone results in decreased expression of ERN1 mRNA CTD PMID:28973697 troglitazone increases expression EXP 6480464 Troglitazone results in increased expression of ERN1 mRNA CTD PMID:32535746 tunicamycin multiple interactions ISO Ern1 (Mus musculus) 6480464 [Tunicamycin co-treated with HRAS protein] results in increased expression of ERN1 protein more ... CTD PMID:20015086 more ... tunicamycin increases expression ISO Ern1 (Mus musculus) 401842386 tunicamycin increases expression of Ern1 mRNA in liver RGD tunicamycin multiple interactions ISO Ern1 (Mus musculus) 401842386 naltrexone inhibits the reaction [tunicamycin increases expression of Ern1 mRNA in liver] RGD tunicamycin increases phosphorylation ISO Ern1 (Rattus norvegicus) 6480464 Tunicamycin results in increased phosphorylation of ERN1 protein CTD PMID:24892553 tunicamycin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Guanabenz inhibits the reaction [Tunicamycin results in increased phosphorylation of ERN1 protein] and KIRA6 inhibits the reaction [Tunicamycin results in increased expression of ERN1 protein] CTD PMID:24892553 and PMID:32740777 tunicamycin multiple interactions EXP 6480464 ERGIC3 protein inhibits the reaction [Tunicamycin results in increased expression of ERN1 protein] more ... CTD PMID:27588471 and PMID:32407927 tunicamycin increases expression ISO Ern1 (Rattus norvegicus) 6480464 Tunicamycin results in increased expression of ERN1 protein CTD PMID:32740777 tunicamycin increases phosphorylation ISO Ern1 (Mus musculus) 6480464 Tunicamycin results in increased phosphorylation of ERN1 protein CTD PMID:22001960 and PMID:30253173 tunicamycin increases expression ISO Ern1 (Mus musculus) 6480464 Tunicamycin results in increased expression of ERN1 mRNA and Tunicamycin results in increased expression of ERN1 protein CTD PMID:17127020 more ... tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of ERN1 mRNA more ... CTD PMID:19139269 more ... urethane increases expression EXP 6480464 Urethane results in increased expression of ERN1 mRNA CTD PMID:28818685 ursolic acid increases activity EXP 6480464 Ursolic Acid results in increased activity of ERN1 protein CTD PMID:24802810 ursolic acid multiple interactions EXP 6480464 Ursolic Acid inhibits the reaction [ochratoxin A results in increased expression of ERN1 protein] CTD PMID:36587836 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of ERN1 gene CTD PMID:29154799 valsartan multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein] CTD PMID:32197949 vanillic acid multiple interactions EXP 6480464 Vanillic Acid inhibits the reaction [INS protein results in increased phosphorylation of ERN1 protein] CTD PMID:36764371 vemurafenib multiple interactions EXP 6480464 [KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased expression of ERN1 protein CTD PMID:27222248 vildagliptin multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Vildagliptin inhibits the reaction [Dietary Fats results in increased phosphorylation of ERN1 protein] CTD PMID:34081941 vinclozolin decreases expression ISO Ern1 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of ERN1 mRNA CTD PMID:23034163 vincristine multiple interactions ISO Ern1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Vincristine results in increased expression of ERN1 mRNA] CTD PMID:33038355 vincristine increases expression ISO Ern1 (Rattus norvegicus) 6480464 Vincristine results in increased expression of ERN1 mRNA CTD PMID:33038355 zerumbone increases expression EXP 6480464 zerumbone results in increased expression of ERN1 mRNA CTD PMID:36122806 zoledronic acid increases expression EXP 6480464 Zoledronic Acid results in increased expression of ERN1 mRNA and Zoledronic Acid results in increased expression of ERN1 protein CTD PMID:35587103
