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Gene: P2RX6 (purinergic receptor P2X 6) Homo sapiens
Symbol: P2RX6
Name: purinergic receptor P2X 6
Description: Predicted to have extracellularly ATP-gated cation channel activity. Predicted to be involved in blood coagulation; muscle contraction; and signal transduction. Localizes to cell junction; cytoplasm; and receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP receptor; MGC129625; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; purinergic receptor P2X, ligand gated ion channel, 6; purinergic receptor P2X, ligand-gated ion channel, 6; purinergic receptor p2x-like 1; purinergic receptor P2X-like 1, orphan receptor; purinoceptor P2X6; purinoreceptor P2X6; skeletal muscle-expressed P2X
Mus musculus (house mouse) : P2rx6 (purinergic receptor P2X, ligand-gated ion channel, 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : P2rx6 (purinergic receptor P2X 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx6 (purinergic receptor P2X 6)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX6 (purinergic receptor P2X 6)
Canis lupus familiaris (dog) : P2RX6 (purinergic receptor P2X 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx6 (purinergic receptor P2X 6)
Sus scrofa (pig) : P2RX6 (purinergic receptor P2X 6)
Heterocephalus glaber (naked mole-rat) : P2rx6 (purinergic receptor P2X 6)
more info ...
Related Pseudogenes: P2RX6P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2221,009,808 - 21,028,830 (+)EnsemblGRCh38hg38GRCh38
GRCh382221,009,699 - 21,028,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372221,369,442 - 21,382,302 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,699,464 - 19,712,302 (+)NCBINCBI36hg18NCBI36
Build 342219,694,002 - 19,707,673NCBI
Celera224,860,745 - 4,873,604 (+)NCBI
Cytogenetic Map22q11.21NCBI
HuRef224,637,727 - 4,650,586 (+)NCBIHuRef
CHM1_12221,369,657 - 21,382,503 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on P2RX6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736820
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.