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Gene: RARA (retinoic acid receptor alpha) Homo sapiens
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Symbol: RARA
Name: retinoic acid receptor alpha
Description: Exhibits several functions, including DNA binding activity; nuclear receptor activity; and transcription coregulator activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of cytokine production; and regulation of leukocyte differentiation. Localizes to the actin cytoskeleton; cytosol; and nuclear lumen. Implicated in acute promyelocytic leukemia. Biomarker of mood disorder.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NR1B1; nuclear receptor subfamily 1 group B member 1; nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form; RAR; RAR-alpha; retinoic acid nuclear receptor alpha variant 1; retinoic acid nuclear receptor alpha variant 2; Retinoic acid receptor, alpha polypeptide
Orthologs:
Mus musculus (house mouse) : Rara (retinoic acid receptor, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rara (retinoic acid receptor, alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rara (retinoic acid receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : RARA (retinoic acid receptor alpha)
Canis lupus familiaris (dog) : RARA (retinoic acid receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rara (retinoic acid receptor alpha)
Sus scrofa (pig) : RARA (retinoic acid receptor alpha)
Chlorocebus sabaeus (green monkey) : RARA (retinoic acid receptor alpha)
Heterocephalus glaber (naked mole-rat) : Rara (retinoic acid receptor alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1740,309,180 - 40,357,643 (+)Ensembl
GRCh381740,309,180 - 40,357,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371738,465,423 - 38,513,895 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,718,972 - 35,767,420 (+)NCBINCBI36hg18NCBI36
Build 341735,740,895 - 35,767,420NCBI
Celera1735,125,565 - 35,174,038 (+)NCBI
Cytogenetic Map17q21.2NCBI
HuRef1734,258,584 - 34,307,018 (+)NCBIHuRef
CHM1_11738,700,731 - 38,749,203 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RARA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733999
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.