CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: phenethyl caffeate
Accession: CHEBI:8062
browse the term
Definition: An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.
Synonyms: exact_synonym: 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
related_synonym: 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate; 2-phenylethyl caffeate; CAPE; Caffeic acid phenethyl ester; Formula=C17H16O4; InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+; InChIKey=SWUARLUWKZWEBQ-VQHVLOKHSA-N; SMILES=Oc1ccc(\\C=C\\C(=O)OCCc2ccccc2)cc1O
xref: CAS:104594-70-9; CAS:115610-29-2; KEGG:C10484; KNApSAcK:C00002766
xref_mesh: MESH:C055494
xref: PDBeChem:QAP; PMID:22206942; PMID:22610380; PMID:22646141; PMID:22964505; PMID:22996076; PMID:23231684; PMID:23291456; PMID:23313590; PMID:23462369; PMID:23466879; PMID:23511289; PMID:23548785; PMID:23561222; PMID:23571777; PMID:23589406; PMID:23611786; PMID:23615471; PMID:23659443; PMID:23662124; PMID:23727925; PMID:23847089; PMID:23876066; PMID:23927014; Patent:US2008167277; Patent:WO2008006070; Reaxys:4752508; Wikipedia:Caffeic_acid_phenethyl_ester
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A2m
alpha-2-macroglobulin
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of A2M mRNA]
CTD
PMID:20360939
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
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Aanat
aralkylamine N-acetyltransferase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AANAT mRNA
CTD
PMID:20360939
NCBI chr10:102,323,647...102,330,639
Ensembl chr10:102,326,135...102,330,635
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Abca5
ATP binding cassette subfamily A member 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCA5 mRNA
CTD
PMID:20360939
NCBI chr10:95,739,610...95,808,633
Ensembl chr10:95,739,610...95,808,424
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Abcc1
ATP binding cassette subfamily C member 1
decreases activity
ISO
caffeic acid phenethyl ester metabolite results in decreased activity of ABCC1 protein
CTD
PMID:15885658
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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Abcc3
ATP binding cassette subfamily C member 3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA
CTD
PMID:20360939
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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Acan
aggrecan
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACAN mRNA
CTD
PMID:20360939
NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
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Acot2
acyl-CoA thioesterase 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACOT2 mRNA
CTD
PMID:20360939
NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502
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Acp5
acid phosphatase 5, tartrate resistant
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of ACP5 protein]
CTD
PMID:28363435
NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
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Ada
adenosine deaminase
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Methotrexate results in increased activity of ADA protein]
CTD
PMID:16325979
NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293
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Adam7
ADAM metallopeptidase domain 7
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADAM7 mRNA
CTD
PMID:20360939
NCBI chr15:47,009,176...47,057,581
Ensembl chr15:47,009,176...47,057,581
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Adcy2
adenylate cyclase 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADCY2 mRNA
CTD
PMID:20360939
NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645
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Adra1d
adrenoceptor alpha 1D
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADRA1D mRNA
CTD
PMID:20360939
NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331
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Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AGAP2 mRNA
CTD
PMID:20360939
NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:64,782,612...64,799,640
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in decreased expression of AHR protein]
CTD
PMID:17204746
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Aimp1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA]
CTD
PMID:16365417
NCBI chr 2:223,825,930...223,849,477
Ensembl chr 2:223,825,931...223,849,994
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Akap9
A-kinase anchoring protein 9
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AKAP9 mRNA
CTD
PMID:20360939
NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338
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Akr1b1
aldo-keto reductase family 1 member B1
decreases activity
ISO
caffeic acid phenethyl ester results in decreased activity of AKR1B1 protein
CTD
PMID:27163852
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
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Akr1b10
aldo-keto reductase family 1 member B10
decreases activity
ISO
caffeic acid phenethyl ester results in decreased activity of AKR1B10 protein
CTD
PMID:27163852
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
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Akr1c1
aldo-keto reductase family 1, member C1
decreases activity
ISO
caffeic acid phenethyl ester results in decreased activity of AKR1C1 protein
CTD
PMID:27163852
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
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Akr1c2
aldo-keto reductase family 1, member C2
decreases activity
ISO
caffeic acid phenethyl ester results in decreased activity of AKR1C2 protein
CTD
PMID:27163852
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
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Akr1c3
aldo-keto reductase family 1, member C3
decreases activity
ISO
caffeic acid phenethyl ester results in decreased activity of AKR1C3 protein
CTD
PMID:27163852
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
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Akt1
AKT serine/threonine kinase 1
affects phosphorylation decreases expression
ISO
caffeic acid phenethyl ester analog affects the phosphorylation of AKT1 protein CAPE decreases expression of AKT1 mRNA in prostate adenocarcinoma cells Caffeic acid phenethyl ester decreases expression of AKT1 protein in oral squamous cell carcinoma cells
CTD RGD
PMID:32125059 PMID:22562408 PMID:23615471
RGD:408364953 , RGD:408364967
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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Alb
albumin
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased expression of ALB protein]
CTD
PMID:34789018
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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Aldh1a2
aldehyde dehydrogenase 1 family, member A2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ALDH1A2 mRNA
CTD
PMID:20360939
NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
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Alpl
alkaline phosphatase, biomineralization associated
multiple interactions
ISO EXP
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of ALPL protein] caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of ALPL protein]
CTD
PMID:18436364 PMID:28363435
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
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Ankrd17
ankyrin repeat domain 17
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ANKRD17 mRNA]
CTD
PMID:20360939
NCBI chr14:18,007,342...18,145,980
Ensembl chr14:18,008,859...18,145,980
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Arrb1
arrestin, beta 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ARRB1 mRNA
CTD
PMID:20360939
NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859
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Atf6
activating transcription factor 6
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA]
CTD
PMID:28223344
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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Atox1
antioxidant 1 copper chaperone
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ATOX1 mRNA]
CTD
PMID:20360939
NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585
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Axl
Axl receptor tyrosine kinase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AXL mRNA
CTD
PMID:20360939
NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
[Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of BAX mRNA
CTD
PMID:24289642
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcar1
BCAR1 scaffold protein, Cas family member
decreases phosphorylation
ISO
caffeic acid phenethyl ester results in decreased phosphorylation of BCAR1 protein
CTD
PMID:10741720
NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190
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Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]
CTD
PMID:34743973
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bgn
biglycan
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of BGN mRNA
CTD
PMID:20360939
NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799
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Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of BIRC2 protein
CTD
PMID:15291876
NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
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Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of BIRC3 protein
CTD
PMID:15291876
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
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Ca3
carbonic anhydrase 3
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAR3 mRNA]
CTD
PMID:20360939
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
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Ca4
carbonic anhydrase 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAR4 mRNA
CTD
PMID:20360939
NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916
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Cacna1a
calcium voltage-gated channel subunit alpha1 A
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1A mRNA
CTD
PMID:20360939
NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599
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Cacna1h
calcium voltage-gated channel subunit alpha1 H
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1H mRNA
CTD
PMID:20360939
NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771
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Camk2d
calcium/calmodulin-dependent protein kinase II delta
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAMK2D mRNA
CTD
PMID:20360939
NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276
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Capn8
calpain 8
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAPN8 mRNA]
CTD
PMID:20360939
NCBI chr13:96,783,640...96,847,825
Ensembl chr13:96,783,667...96,847,820
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Casp1
caspase 1
decreases expression
EXP
caffeic acid phenethyl ester results in decreased expression of CASP1 protein
CTD
PMID:15469948
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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Casp3
caspase 3
decreases activity multiple interactions increases activity
EXP ISO
caffeic acid phenethyl ester results in decreased activity of CASP3 protein caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased activity of CASP3 protein]; caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein] caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein] caffeic acid phenethyl ester analog results in increased activity of CASP3 protein
CTD
PMID:15469948 PMID:18436364 PMID:28363435 PMID:32125059 PMID:34743973
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp8
caspase 8
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP8 protein]
CTD
PMID:18436364
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Casp9
caspase 9
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased activity of CASP9 protein]
CTD
PMID:34743973
Ensembl chr 5:159,391,188...159,409,648
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Cat
catalase
multiple interactions
EXP ISO
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased activity of CAT protein]; caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; caffeic acid phenethyl ester promotes the reaction [Doxorubicin results in increased activity of CAT protein] caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]
CTD
PMID:14745846 PMID:15369732 PMID:18436364 PMID:23570914 PMID:34789018
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of CCL2 mRNA]
CTD
PMID:16085347
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Ccl5
C-C motif chemokine ligand 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CCL5 mRNA
CTD
PMID:20360939
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
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Ccnb1
cyclin B1
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of CCNB1 protein
CTD
PMID:16085347
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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Ccnd1
cyclin D1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased expression of CCND1 mRNA; caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of CCND1 protein]
CTD
PMID:20420878 PMID:24289642
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Ccne1
cyclin E1
multiple interactions
EXP ISO
caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein] [Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein]
CTD
PMID:15885897 PMID:16766008
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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Cd14
CD14 molecule
multiple interactions increases expression
EXP ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD14 mRNA caffeic acid phenethyl ester results in increased expression of CD14 protein caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of CD14 protein]
CTD
PMID:16766008 PMID:20360939
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
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Cd151
CD151 molecule (Raph blood group)
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD151 mRNA
CTD
PMID:20360939
NCBI chr 1:205,994,300...205,998,307
Ensembl chr 1:205,994,738...205,998,784
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Cd86
CD86 molecule
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD86 mRNA
CTD
PMID:20360939
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
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Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of CDK1 protein
CTD
PMID:16085347
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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Cdk2
cyclin dependent kinase 2
multiple interactions
EXP ISO
caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein] [Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein]
CTD
PMID:15885897 PMID:16766008
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression multiple interactions
ISO EXP
caffeic acid phenethyl ester results in increased expression of CDKN1A protein [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of CDKN1A mRNA; caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein]; Tretinoin promotes the reaction [caffeic acid phenethyl ester results in increased expression of CDKN1A protein]
CTD
PMID:15885897 PMID:16766008 PMID:24289642 PMID:26056802
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
increases expression multiple interactions
EXP ISO
caffeic acid phenethyl ester results in increased expression of CDKN1B protein caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1B protein]
CTD
PMID:15885897 PMID:26056802
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
increases expression multiple interactions
EXP
caffeic acid phenethyl ester results in increased expression of CDKN2A protein caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA]
CTD
PMID:15885897 PMID:20360939
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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Cdkn2c
cyclin-dependent kinase inhibitor 2C
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CDKN2C mRNA
CTD
PMID:20360939
NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
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Ceacam4
CEA cell adhesion molecule 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CEACAM10 mRNA
CTD
PMID:20360939
NCBI chr 1:89,504,555...89,510,831
Ensembl chr 1:89,504,555...89,510,831
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Cebpe
CCAAT/enhancer binding protein epsilon
multiple interactions increases expression
ISO
Tretinoin promotes the reaction [caffeic acid phenethyl ester results in increased expression of CEBPE protein]
CTD
PMID:16766008
NCBI chr15:32,139,716...32,141,476
Ensembl chr15:32,139,716...32,141,476
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Cers2
ceramide synthase 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA]
CTD
PMID:28223344
NCBI chr 2:185,579,511...185,587,789
Ensembl chr 2:185,579,119...185,588,839
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Cers4
ceramide synthase 4
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA]
CTD
PMID:28223344
NCBI chr12:7,649,610...7,688,066
Ensembl chr12:7,649,610...7,688,070
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Cgm4
carcinoembryonic antigen gene family 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CGM4 mRNA
CTD
PMID:20360939
NCBI chr 1:86,904,526...86,917,487
Ensembl chr 1:86,904,526...86,917,475
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Chrna2
cholinergic receptor nicotinic alpha 2 subunit
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CHRNA2 mRNA
CTD
PMID:20360939
NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144
G
Chrne
cholinergic receptor nicotinic epsilon subunit
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CHRNE mRNA
CTD
PMID:20360939
NCBI chr10:55,829,835...55,838,853
Ensembl chr10:55,829,836...55,834,154
G
Clcn1
chloride voltage-gated channel 1
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CLCN1 mRNA]
CTD
PMID:20360939
NCBI chr 4:72,138,739...72,168,113
Ensembl chr 4:72,139,162...72,168,128
G
Cldn2
claudin 2
decreases expression multiple interactions
ISO
caffeic acid phenethyl ester results in decreased expression of CLDN2 mRNA; caffeic acid phenethyl ester results in decreased expression of CLDN2 protein Cantharidin inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein]; Chloroquine inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein]; CLDN2 protein inhibits the reaction [caffeic acid phenethyl ester results in increased susceptibility to and results in increased activity of Doxorubicin]
CTD
PMID:29597147
NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377
G
Cldn7
claudin 7
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLDN7 mRNA
CTD
PMID:20360939
NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905
G
Clic5
chloride intracellular channel 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLIC5 mRNA
CTD
PMID:20360939
NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780
G
Clock
clock circadian regulator
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLOCK mRNA
CTD
PMID:20360939
NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872
G
Col18a1
collagen type XVIII alpha 1 chain
increases expression
ISO
caffeic acid phenethyl ester results in increased expression of COL18A1 protein
CTD
PMID:20433813
NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112
G
Cox4i2
cytochrome c oxidase subunit 4i2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX4I2 mRNA
CTD
PMID:20360939
NCBI chr 3:161,686,193...161,699,605
Ensembl chr 3:161,689,017...161,699,602
G
Cox6a2
cytochrome c oxidase subunit 6A2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX6A2 mRNA
CTD
PMID:20360939
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
G
Cox7a2
cytochrome c oxidase subunit 7A2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of COX7A2 mRNA]
CTD
PMID:20360939
NCBI chr 8:89,597,051...89,611,032
Ensembl chr14:55,514,261...55,514,512 Ensembl chr 8:55,514,261...55,514,512
G
Crmp1
collapsin response mediator protein 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRMP1 mRNA
CTD
PMID:20360939
NCBI chr14:77,734,675...77,780,916
Ensembl chr14:77,734,675...77,780,916
G
Crp
C-reactive protein
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of CRP protein]
CTD
PMID:34789018
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
G
Cryge
crystallin, gamma E
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRYGE mRNA
CTD
PMID:20360939
NCBI chr 9:73,923,661...73,926,258
Ensembl chr 9:73,923,661...73,927,011
G
Cs
citrate synthase
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein; [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA]
CTD
PMID:28223344
NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938
G
Csk
C-terminal Src kinase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSK mRNA
CTD
PMID:20360939
NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:66,925,651...66,930,274
G
Cspg4
chondroitin sulfate proteoglycan 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSPG4 mRNA
CTD
PMID:20360939
NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:66,160,942...66,200,806
G
Ctnnb1
catenin beta 1
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of CTNNB1 protein
CTD
PMID:10783313
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
G
Ctsk
cathepsin K
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CTSK mRNA
CTD
PMID:20360939
NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
G
Ctsm
cathepsin M
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CTSM mRNA
CTD
PMID:20360939
NCBI chr17:3,242,488...3,247,896
Ensembl chr17:3,242,488...3,247,896
G
Ctsr
cathepsin R
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CTSR mRNA]
CTD
PMID:20360939
NCBI chr17:3,527,990...3,536,753
Ensembl chr17:3,527,990...3,536,746
G
Cxcr3
C-X-C motif chemokine receptor 3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CXCR3 mRNA
CTD
PMID:20360939
NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871
G
Cyb5a
cytochrome b5 type A
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYB5A mRNA]
CTD
PMID:20360939
NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094 Ensembl chr18:14,453,966...14,455,094
G
Cyba
cytochrome b-245 alpha chain
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CYBA mRNA]
CTD
PMID:20360939
NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
G
Cycs
cytochrome c, somatic
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]
CTD
PMID:15469948
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions decreases expression
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA caffeic acid phenethyl ester results in decreased expression of CYP1A2 protein
CTD
PMID:20360939 PMID:22291063
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
G
Cyp2a2
cytochrome P450, family 2, subfamily a, polypeptide 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2A2 mRNA
CTD
PMID:20360939
NCBI chr 1:91,391,492...91,417,158
Ensembl chr 1:91,391,502...91,417,158
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
multiple interactions decreases expression
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2B1 mRNA caffeic acid phenethyl ester results in decreased expression of CYP2B1 protein
CTD
PMID:20360939 PMID:22291063
NCBI chr 1:90,646,098...90,669,762
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
decreases expression
EXP
caffeic acid phenethyl ester results in decreased expression of CYP2B2 protein
CTD
PMID:22291063
NCBI chr 1:90,722,243...90,736,272
G
Cyp2c13
cytochrome P450, family 2, subfamily c, polypeptide 13
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2C13 mRNA]
CTD
PMID:20360939
NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
EXP ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]
CTD
PMID:18436364 PMID:20360939
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
G
Cyp3a18
cytochrome P450, family 3, subfamily a, polypeptide 18
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP3A18 mRNA]
CTD
PMID:20360939
NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788
G
Cyth2
cytohesin 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CYTH2 mRNA
CTD
PMID:20360939
NCBI chr 1:105,419,631...105,427,542
Ensembl chr 1:105,419,631...105,427,542
G
Dbn1
drebrin 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DBN1 mRNA
CTD
PMID:20360939
NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA]
CTD
PMID:28223344
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
G
Deaf1
DEAF1 transcription factor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DEAF1 mRNA
CTD
PMID:20360939
NCBI chr 1:205,831,428...205,865,106
Ensembl chr 1:205,831,336...205,865,106
G
Degs1
delta(4)-desaturase, sphingolipid 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DEGS1 mRNA
CTD
PMID:20360939
NCBI chr13:96,478,645...96,485,302
Ensembl chr13:96,478,646...96,485,302
G
Degs2
delta(4)-desaturase, sphingolipid 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA]
CTD
PMID:28223344
NCBI chr 6:133,360,449...133,377,677
Ensembl chr 6:133,360,457...133,364,422
G
Dgkb
diacylglycerol kinase, beta
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DGKB mRNA
CTD
PMID:20360939
NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:60,368,519...61,124,420
G
Dhfr
dihydrofolate reductase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DHFR mRNA
CTD
PMID:20360939
NCBI chr 2:25,320,895...25,346,004
G
Disc1
DISC1 scaffold protein
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of DISC1 mRNA]
CTD
PMID:20360939
NCBI chr19:69,911,548...70,120,970
Ensembl chr19:69,911,976...70,120,970
G
Dmrt1
doublesex and mab-3 related transcription factor 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DMRT1 mRNA
CTD
PMID:20360939
NCBI chr 1:232,569,179...232,667,646
Ensembl chr 1:232,569,072...232,668,370
G
Dnah10
dynein, axonemal, heavy chain 10
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH10 mRNA
CTD
PMID:20360939
NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860
G
Dnah5
dynein, axonemal, heavy chain 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH5 mRNA
CTD
PMID:20360939
NCBI chr 2:80,668,182...80,985,918
Ensembl chr 2:80,668,208...80,985,914
G
Dpys
dihydropyrimidinase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DPYS mRNA
CTD
PMID:20360939
NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:72,721,048...72,814,142
G
Dusp6
dual specificity phosphatase 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DUSP6 mRNA
CTD
PMID:20360939
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
G
E2f6
E2F transcription factor 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of E2F6 mRNA
CTD
PMID:20360939
NCBI chr 6:45,320,993...45,337,437
Ensembl chr 6:45,320,996...45,337,428
G
Echs1
enoyl-CoA hydratase, short chain 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ECHS1 mRNA
CTD
PMID:20360939
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
G
Edn1
endothelin 1
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein]
CTD
PMID:21926265
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
G
Ets1
ETS proto-oncogene 1, transcription factor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ETS1 mRNA
CTD
PMID:20360939
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
G
Fabp7
fatty acid binding protein 7
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FABP7 mRNA
CTD
PMID:20360939
NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907
G
Fas
Fas cell surface death receptor
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased expression of FAS protein]
CTD
PMID:18436364
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
G
Faslg
Fas ligand
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased expression of FASL protein]
CTD
PMID:18436364
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
G
Fgf19
fibroblast growth factor 19
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA]
CTD
PMID:28223344
NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267
G
Fgf7
fibroblast growth factor 7
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FGF7 mRNA
CTD
PMID:20360939
NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
G
Fgg
fibrinogen gamma chain
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of FGG mRNA
CTD
PMID:20360939
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
G
Fmo2
flavin containing dimethylaniline monoxygenase 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FMO2 mRNA
CTD
PMID:20360939
NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534
G
Foxc2
forkhead box C2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FOXC2 mRNA
CTD
PMID:20360939
NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977
G
Foxd1
forkhead box D1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FOXD1 mRNA
CTD
PMID:20360939
NCBI chr 2:31,436,802...31,439,222
Ensembl chr 2:31,436,813...31,439,399
G
Frmd6
FERM domain containing 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FRMD6 mRNA
CTD
PMID:20360939
NCBI chr 6:95,081,958...95,155,561
Ensembl chr 6:95,081,985...95,155,560
G
Ftl1
ferritin light chain 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FTL mRNA
CTD
PMID:20360939
NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915 Ensembl chr 2:45,399,355...45,399,915 Ensembl chr 1:45,399,355...45,399,915
G
Fut2
fucosyltransferase 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FUT2 mRNA
CTD
PMID:20360939
NCBI chr 1:105,256,013...105,276,828
Ensembl chr 1:105,255,390...105,276,647
G
Gas6
growth arrest specific 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GAS6 mRNA
CTD
PMID:20360939
NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
G
Gc
GC, vitamin D binding protein
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNA
CTD
PMID:20360939
NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673
G
Gch1
GTP cyclohydrolase 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GCH1 mRNA
CTD
PMID:20360939
NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412
G
Gclc
glutamate-cysteine ligase, catalytic subunit
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein]
CTD
PMID:23570914
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
G
Gdnf
glial cell derived neurotrophic factor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GDNF mRNA
CTD
PMID:20360939
NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
G
Gfap
glial fibrillary acidic protein
multiple interactions increases expression
EXP
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of GFAP protein]
CTD
PMID:20836997
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
G
Gfer
growth factor, augmenter of liver regeneration
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GFER mRNA
CTD
PMID:20360939
NCBI chr10:14,223,023...14,225,736
Ensembl chr10:14,223,023...14,225,935
G
Gfra4
GDNF family receptor alpha 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GFRA4 mRNA
CTD
PMID:20360939
NCBI chr 3:138,707,970...138,715,279
Ensembl chr 3:138,703,114...138,711,561
G
Ghr
growth hormone receptor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GHR mRNA
CTD
PMID:20360939
NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
G
Gjb1
gap junction protein, beta 1
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B protein]
CTD
PMID:15350541
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
G
Gjc2
gap junction protein, gamma 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GJC2 mRNA
CTD
PMID:20360939
NCBI chr10:44,462,203...44,470,924
Ensembl chr10:44,462,054...44,470,340
G
Gls
glutaminase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GLS mRNA
CTD
PMID:20360939
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861
G
Gnal
G protein subunit alpha L
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GNAL mRNA
CTD
PMID:20360939
NCBI chr18:62,892,257...63,032,510
Ensembl chr18:62,892,226...63,043,129
G
Golga2
golgin A2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GOLGA2 mRNA
CTD
PMID:20360939
NCBI chr 3:35,981,783...36,002,023
Ensembl chr 3:35,981,499...36,002,022
G
Gpr19
G protein-coupled receptor 19
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GPR19 mRNA
CTD
PMID:20360939
NCBI chr 4:169,442,278...169,468,805
Ensembl chr 4:169,436,658...169,471,249
G
Grik2
glutamate ionotropic receptor kainate type subunit 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GRIK2 mRNA
CTD
PMID:20360939
NCBI chr20:53,717,564...54,415,283
Ensembl chr20:53,716,090...54,415,202
G
Grik5
glutamate ionotropic receptor kainate type subunit 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GRIK5 mRNA
CTD
PMID:20360939
NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:89,733,741...89,794,962
G
Gsr
glutathione-disulfide reductase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GSR mRNA
CTD
PMID:20360939
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
G
Gstk1
glutathione S-transferase kappa 1
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of GSTK1 mRNA]
CTD
PMID:20360939
NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927
G
Gstp1
glutathione S-transferase pi 1
decreases expression
EXP
caffeic acid phenethyl ester results in decreased expression of GSTP1 protein
CTD
PMID:17106925
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Gstt2
glutathione S-transferase theta 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of GSTT2 mRNA]
CTD
PMID:20360939
NCBI chr20:12,819,053...12,822,724
Ensembl chr20:12,818,540...12,822,718
G
Gyg1
glycogenin 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GYG1 mRNA
CTD
PMID:20360939
NCBI chr 2:104,540,927...104,583,038
Ensembl chr 2:104,540,533...104,582,818
G
H2ac1
H2A clustered histone 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of H2AC1 mRNA
CTD
PMID:20360939
NCBI chr17:41,599,195...41,599,672
Ensembl chr17:41,599,074...41,599,842
G
Hamp
hepcidin antimicrobial peptide
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HAMP mRNA
CTD
PMID:20360939
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
G
Hdgf
heparin binding growth factor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HDGF mRNA
CTD
PMID:20360939
NCBI chr 2:175,668,290...175,677,614
Ensembl chr 2:175,668,324...175,677,225
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of HMGCS2 mRNA]
CTD
PMID:20360939
NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242
G
Hmox1
heme oxygenase 1
increases expression multiple interactions
EXP ISO
caffeic acid phenethyl ester results in increased expression of HMOX1 protein caffeic acid phenethyl ester analog results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester analog results in increased expression of HMOX1 protein; caffeic acid phenethyl ester results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester results in increased expression of HMOX1 protein caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased expression of HMOX1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of HMOX1 protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]
CTD
PMID:20226179 PMID:20950636 PMID:21472898 PMID:23942037 PMID:24508943 PMID:34789018 More...
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HNRNPR mRNA
CTD
PMID:20360939
NCBI chr 5:153,826,482...153,872,272
Ensembl chr 5:153,826,692...153,858,344
G
Hpcal4
hippocalcin-like 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HPCAL4 mRNA
CTD
PMID:20360939
NCBI chr 5:140,739,577...140,751,529
Ensembl chr 5:140,739,635...140,751,530
G
Hspa2
heat shock protein family A (Hsp70) member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPA2 mRNA
CTD
PMID:20360939
NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA]
CTD
PMID:28223344
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
G
Hspb1
heat shock protein family B (small) member 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPB1 mRNA
CTD
PMID:20360939
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
G
Hspb2
heat shock protein family B (small) member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPB2 mRNA
CTD
PMID:20360939
NCBI chr 8:59,989,640...59,991,215
Ensembl chr 8:59,976,623...59,990,901
G
Icam1
intercellular adhesion molecule 1
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]
CTD
PMID:34789018
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
G
Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA]
CTD
PMID:28223344
NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223
G
Idh3b
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA]
CTD
PMID:28223344
NCBI chr 3:137,934,971...137,940,275
Ensembl chr 3:137,934,697...137,940,107
G
Idh3g
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA]
CTD
PMID:28223344
NCBI chr X:156,666,573...156,675,482
Ensembl chr X:156,666,577...156,675,799
G
Ido1
indoleamine 2,3-dioxygenase 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IDO1 mRNA
CTD
PMID:20360939
NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328
G
Ifng
interferon gamma
multiple interactions
ISO
[Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased expression of IFNG protein; caffeic acid phenethyl ester inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]]
CTD
PMID:18953428 PMID:24289642
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
G
Igbp1
immunoglobulin binding protein 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IGBP1 mRNA
CTD
PMID:20360939
NCBI chr X:69,622,925...69,645,167
Ensembl chr X:69,622,917...69,646,149
G
Il12b
interleukin 12B
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA]
CTD
PMID:16365417
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
G
Il18
interleukin 18
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL18 mRNA]
CTD
PMID:16085347
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
G
Il1a
interleukin 1 alpha
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA]
CTD
PMID:16085347
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
G
Il1b
interleukin 1 beta
multiple interactions
EXP ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IL1B mRNA; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B protein] caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]
CTD
PMID:15350541 PMID:20360939 PMID:34743973 PMID:34789018
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il2
interleukin 2
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL2 mRNA]
CTD
PMID:16085347
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
G
Il6
interleukin 6
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of IL6 protein]
CTD
PMID:34743973
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Ins1
insulin 1
multiple interactions
ISO
[[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in decreased expression of INS1 protein
CTD
PMID:28223344
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
G
Insrr
insulin receptor-related receptor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of INSRR mRNA
CTD
PMID:20360939
NCBI chr 2:175,553,244...175,572,676
Ensembl chr 2:175,553,293...175,572,676
G
Ip6k2
inositol hexakisphosphate kinase 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of IP6K2 mRNA]
CTD
PMID:20360939
NCBI chr 8:118,362,154...118,388,668
Ensembl chr 8:118,362,795...118,388,667
G
Irs1
insulin receptor substrate 1
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of IRS1 mRNA
CTD
PMID:21467634
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
G
Itgam
integrin subunit alpha M
multiple interactions increases expression
ISO
caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of ITGAM protein] caffeic acid phenethyl ester results in increased expression of ITGAM protein
CTD
PMID:16766008
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
G
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA]
CTD
PMID:28223344
NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504
G
Itpr2
inositol 1,4,5-trisphosphate receptor, type 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA]
CTD
PMID:28223344
NCBI chr 4:180,759,325...181,165,361
Ensembl chr 4:180,760,442...181,164,763
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [arsenite results in increased expression of JUN mRNA]
CTD
PMID:16085347
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
G
Kalrn
kalirin, RhoGEF kinase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KALRN mRNA
CTD
PMID:20360939
NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329
G
Kcng3
potassium voltage-gated channel modifier subfamily G member 3
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KCNG3 mRNA]
CTD
PMID:20360939
NCBI chr 6:16,803,842...16,851,791
Ensembl chr 6:16,803,665...16,851,791
G
Kcnh5
potassium voltage-gated channel subfamily H member 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNH5 mRNA
CTD
PMID:20360939
NCBI chr 6:99,350,947...99,643,856
Ensembl chr 6:99,360,302...99,643,856
G
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of KCNJ2 mRNA
CTD
PMID:20360939
NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901
G
Kcnmb2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNMB2 mRNA
CTD
PMID:20360939
NCBI chr 2:116,598,511...116,903,886
Ensembl chr 2:116,599,387...116,903,854
G
Kcnq2
potassium voltage-gated channel subfamily Q member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNQ2 mRNA
CTD
PMID:20360939
NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302
G
Kcnt2
potassium sodium-activated channel subfamily T member 2
decreases expression
EXP
caffeic acid phenethyl ester results in decreased expression of KCNT2 mRNA
CTD
PMID:26100633
NCBI chr13:54,214,831...54,609,889
Ensembl chr13:54,215,307...54,607,924
G
Kif6
kinesin family member 6
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KIF6 mRNA]
CTD
PMID:20360939
NCBI chr 9:18,573,925...18,870,789
Ensembl chr 9:18,573,789...18,870,729
G
Klhl17
kelch-like family member 17
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KLHL17 mRNA
CTD
PMID:20360939
NCBI chr 5:172,095,701...172,101,945
Ensembl chr 5:172,094,940...172,101,195
G
Klre1
killer cell lectin like receptor E1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KLRE1 mRNA
CTD
PMID:20360939
NCBI chr 4:164,719,307...164,727,664
Ensembl chr 4:164,719,604...164,727,664
G
Lalba
lactalbumin, alpha
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LALBA mRNA
CTD
PMID:20360939
NCBI chr 7:131,504,572...131,520,707
Ensembl chr 7:131,504,572...131,507,072
G
Lep
leptin
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of LEP mRNA; caffeic acid phenethyl ester results in decreased expression of LEP protein
CTD
PMID:21467634
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
G
Leprot
leptin receptor overlapping transcript
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LEPROT mRNA
CTD
PMID:20360939
NCBI chr 5:121,405,170...121,417,273
Ensembl chr 5:121,404,759...121,417,275
G
Lgi1
leucine-rich, glioma inactivated 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LGI1 mRNA
CTD
PMID:20360939
NCBI chr 1:245,455,691...245,497,036
Ensembl chr 1:245,455,599...245,499,095
G
Lmna
lamin A/C
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LMNA mRNA
CTD
PMID:20360939
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072
G
Lrrc15
leucine rich repeat containing 15
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LRRC15 mRNA
CTD
PMID:20360939
NCBI chr11:83,974,708...83,989,157
Ensembl chr11:83,974,695...83,989,146
G
Mapk1
mitogen activated protein kinase 1
affects phosphorylation
ISO
caffeic acid phenethyl ester analog affects the phosphorylation of MAPK1 protein
CTD
PMID:32125059
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
G
Mapk14
mitogen activated protein kinase 14
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of MAPK14 mRNA]
CTD
PMID:20360939 PMID:34789018
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
G
Mapk3
mitogen activated protein kinase 3
affects phosphorylation
ISO
caffeic acid phenethyl ester analog affects the phosphorylation of MAPK3 protein
CTD
PMID:32125059
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
G
Me1
malic enzyme 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ME1 mRNA
CTD
PMID:20360939
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
G
Mfn2
mitofusin 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA]
CTD
PMID:28223344
NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
G
Mir182
microRNA 182
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in decreased expression of MIR182 mRNA]
CTD
PMID:34743973
NCBI chr 4:59,752,246...59,752,307
G
Mmp2
matrix metallopeptidase 2
decreases activity multiple interactions
EXP
caffeic acid phenethyl ester results in decreased activity of MMP2 protein NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP2 protein]
CTD
PMID:20836997
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
G
Mmp3
matrix metallopeptidase 3
multiple interactions
EXP ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MMP3 mRNA caffeic acid phenethyl ester inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP3 protein]
CTD
PMID:20360939 PMID:34791780
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
G
Mmp9
matrix metallopeptidase 9
decreases expression multiple interactions decreases activity
ISO EXP
caffeic acid phenethyl ester results in decreased expression of MMP9 protein NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP9 protein]
CTD
PMID:20433813 PMID:20836997
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
G
Mpo
myeloperoxidase
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of MPO mRNA]; caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in increased activity of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]
CTD
PMID:15369732 PMID:20693123 PMID:21472898 PMID:34789018
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
G
Mprip
myosin phosphatase Rho interacting protein
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MPRIP mRNA
CTD
PMID:20360939
NCBI chr10:44,953,472...45,073,388
Ensembl chr10:44,953,500...45,073,388
G
Msx2
msh homeobox 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MSX2 mRNA
CTD
PMID:20360939
NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945
G
Mterf1
mitochondrial transcription termination factor 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MTERF1 mRNA
CTD
PMID:20360939
NCBI chr 4:31,181,048...31,188,130
Ensembl chr 4:31,180,832...31,189,651
G
Mtus1
microtubule associated scaffold protein 1
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of MTUS1 mRNA]
CTD
PMID:20360939
NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474
G
Muc1
mucin 1, cell surface associated
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MUC1 mRNA
CTD
PMID:20360939
NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491
G
Mug2
murinoglobulin 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PZP mRNA
CTD
PMID:20360939
NCBI chr 4:156,836,140...156,908,972
G
Mxi1
MAX interactor 1, dimerization protein
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MXI1 mRNA
CTD
PMID:20360939
NCBI chr 1:262,329,274...262,389,037
Ensembl chr 1:262,328,875...262,389,036
G
Myo9a
myosin IXA
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MYO9A mRNA
CTD
PMID:20360939
NCBI chr 8:69,044,853...69,248,094
Ensembl chr 8:69,044,885...69,245,231
G
Nat8b
N-acetyltransferase 8B
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NAT8B mRNA
CTD
PMID:20360939
NCBI chr 4:119,916,909...119,923,544
Ensembl chr 4:119,915,525...119,921,887
G
Ncam1
neural cell adhesion molecule 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NCAM1 mRNA
CTD
PMID:20360939
NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971
G
Ndufa10l1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NDUFA10L1 mRNA
CTD
PMID:20360939
NCBI chr 6:65,606,866...65,608,299
Ensembl chr 6:65,606,574...65,608,305
G
Neo1
neogenin 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NEO1 mRNA
CTD
PMID:20360939
NCBI chr 8:68,169,711...68,322,158
Ensembl chr 8:68,169,716...68,322,152
G
Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO EXP
caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in increased expression of NFE2L2 protein] caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein] caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased expression of NFE2L2 mRNA]
CTD
PMID:17204746 PMID:23570914 PMID:34789018
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
G
Nfia
nuclear factor I/A
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NFIA mRNA
CTD
PMID:20360939
NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395
G
Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO EXP
caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased activity of [NFKB1 protein binds to RELA protein]] caffeic acid phenethyl ester results in decreased activity of [NFKB1 protein binds to RELA protein] caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of NFKB1 mRNA]
CTD
PMID:11259437 PMID:16052512 PMID:34789018
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
G
Nfkb2
nuclear factor kappa B subunit 2
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of NFKB2 protein]
CTD
PMID:20420878
NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
G
Nfkbia
NFKB inhibitor alpha
decreases phosphorylation
EXP
caffeic acid phenethyl ester results in decreased phosphorylation of NFKBIA protein
CTD
PMID:20836997
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
G
Nfya
nuclear transcription factor Y subunit alpha
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of NFYA mRNA]
CTD
PMID:20360939
NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504
G
Ngf
nerve growth factor
increases expression
EXP
caffeic acid phenethyl ester results in increased expression of NGF protein
CTD
PMID:20836997
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
G
Ngfr
nerve growth factor receptor
increases expression multiple interactions affects response to substance
EXP
caffeic acid phenethyl ester results in increased expression of NGFR protein NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP2 protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP9 protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of GFAP protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of RHOB protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of S100B protein] NGFR protein affects the susceptibility to caffeic acid phenethyl ester
CTD
PMID:20836997
NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305
G
Nog
noggin
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NOG mRNA
CTD
PMID:20360939
NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103
G
Nos2
nitric oxide synthase 2
decreases expression multiple interactions
EXP
caffeic acid phenethyl ester results in decreased expression of NOS2 protein caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]
CTD
PMID:15469948 PMID:34789018
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
G
Notch2
notch receptor 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NOTCH2 mRNA
CTD
PMID:20360939
NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823
G
Nox4
NADPH oxidase 4
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of NOX4 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of NOX4 protein]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 protein]
CTD
PMID:24224404
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
G
Nr0b2
nuclear receptor subfamily 0, group B, member 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of NR0B2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of NR0B2 mRNA]
CTD
PMID:28223344
NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475
G
Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions
ISO
[[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in decreased expression of INS1 protein; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of Citric Acid; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of Fumarates; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of Ketoglutaric Acids; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of malic acid; [NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA]
CTD
PMID:28223344
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
G
Nrtn
neurturin
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NRTN mRNA
CTD
PMID:20360939
NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,641,618...1,675,133
G
Nup88
nucleoporin 88
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of NUP88 mRNA
CTD
PMID:20360939
NCBI chr10:56,166,486...56,190,829
Ensembl chr10:56,166,486...56,191,383
G
Odf1
outer dense fiber of sperm tails 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ODF1 mRNA
CTD
PMID:20360939
NCBI chr 7:71,262,270...71,274,621
Ensembl chr 7:71,266,838...71,274,620
G
Olig1
oligodendrocyte transcription factor 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of OLIG1 mRNA
CTD
PMID:20360939
NCBI chr11:44,000,450...44,002,592
Ensembl chr11:44,000,281...44,002,592
G
Olr1
oxidized low density lipoprotein receptor 1
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]
CTD
PMID:24145059
NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598
G
Opa1
OPA1, mitochondrial dynamin like GTPase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of OPA1 mRNA
CTD
PMID:20360939
NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
G
Pacs2
phosphofurin acidic cluster sorting protein 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA]
CTD
PMID:28223344
NCBI chr 6:137,918,040...137,977,767
Ensembl chr 6:137,918,051...137,977,767
G
Pard3
par-3 family cell polarity regulator
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PARD3 mRNA
CTD
PMID:20360939
NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941
G
Pc
pyruvate carboxylase
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased activity of PC protein; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased activity of PC protein]
CTD
PMID:28223344
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
G
Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PCK1 mRNA
CTD
PMID:20360939
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
G
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PCSK1N mRNA
CTD
PMID:20360939
NCBI chr X:17,251,963...17,255,405
Ensembl chr X:17,251,965...17,257,360
G
Pcsk2
proprotein convertase subtilisin/kexin type 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of PCSK2 mRNA]
CTD
PMID:20360939
NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849
G
Pcsk6
proprotein convertase subtilisin/kexin type 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PCSK6 mRNA
CTD
PMID:20360939
NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128
G
Pdgfrb
platelet derived growth factor receptor beta
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PDGFRB mRNA
CTD
PMID:20360939
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
G
Per3
period circadian regulator 3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PER3 mRNA
CTD
PMID:20360939
NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999
G
Pfkp
phosphofructokinase, platelet
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PFKP mRNA
CTD
PMID:20360939
NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
G
Phkg2
phosphorylase kinase catalytic subunit gamma 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of PHKG2 mRNA]
CTD
PMID:20360939
NCBI chr 1:191,614,738...191,627,615
Ensembl chr 1:191,614,865...191,627,616
G
Pias2
protein inhibitor of activated STAT, 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PIAS2 mRNA
CTD
PMID:20360939
NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662
G
Pla2g2a
phospholipase A2 group IIA
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]]
CTD
PMID:18953428
NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297
G
Plcg1
phospholipase C, gamma 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PLCG1 mRNA
CTD
PMID:20360939
NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050
G
Plekha5
pleckstrin homology domain containing A5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PLEKHA5 mRNA
CTD
PMID:20360939
NCBI chr 4:175,065,011...175,234,672
Ensembl chr 4:175,065,183...175,234,672
G
Pold1
DNA polymerase delta 1, catalytic subunit
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA]
CTD
PMID:20360939
NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982
G
Polg
DNA polymerase gamma, catalytic subunit
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of POLG mRNA
CTD
PMID:20360939
NCBI chr 1:142,792,119...142,808,933
Ensembl chr 1:142,792,119...142,808,838
G
Pparg
peroxisome proliferator-activated receptor gamma
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of PPARG mRNA
CTD
PMID:21467634
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ppp2r2a
protein phosphatase 2, regulatory subunit B, alpha
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PPP2R2A mRNA
CTD
PMID:20360939
NCBI chr15:45,380,142...45,439,428
Ensembl chr15:45,379,683...45,439,405
G
Ppp4c
protein phosphatase 4, catalytic subunit
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PPP4C mRNA
CTD
PMID:20360939
NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168
G
Prep
prolyl endopeptidase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PREP mRNA
CTD
PMID:20360939
NCBI chr20:50,138,588...50,235,549
Ensembl chr20:50,131,819...50,252,697
G
Prkaca
protein kinase cAMP-activated catalytic subunit alpha
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRKACA mRNA
CTD
PMID:20360939
NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494
G
Prkar2a
protein kinase cAMP-dependent type II regulatory subunit alpha
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRKAR2A mRNA
CTD
PMID:20360939
NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330
G
Prkce
protein kinase C, epsilon
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRKCE mRNA
CTD
PMID:20360939
NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288
G
Prok2
prokineticin 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of PROK2 mRNA]
CTD
PMID:20360939
NCBI chr 4:133,903,210...133,918,126
Ensembl chr 4:133,903,210...133,917,933
G
Prom1
prominin 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PROM1 mRNA
CTD
PMID:20360939
NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002
G
Prss12
serine protease 12
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRSS12 mRNA
CTD
PMID:20360939
NCBI chr 2:214,308,695...214,368,679
Ensembl chr 2:214,308,774...214,369,941
G
Prss3
serine protease 3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRSS3 mRNA
CTD
PMID:20360939
NCBI chr 4:71,169,749...71,173,223
Ensembl chr 4:71,169,749...71,173,223
G
Psma7
proteasome 20S subunit alpha 7
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PSMA7 mRNA
CTD
PMID:20360939
NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]
CTD
PMID:34789018
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Ptk2
protein tyrosine kinase 2
decreases phosphorylation
ISO
caffeic acid phenethyl ester results in decreased phosphorylation of PTK2 protein
CTD
PMID:10741720
NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
G
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PTPN1 mRNA
CTD
PMID:20360939
NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416
G
Ramp1
receptor activity modifying protein 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RAMP1 mRNA
CTD
PMID:20360939
NCBI chr 9:99,213,031...99,263,696
G
Rara
retinoic acid receptor, alpha
increases activity increases expression multiple interactions
ISO
caffeic acid phenethyl ester results in increased activity of RARA protein caffeic acid phenethyl ester results in increased expression of RARA mRNA; caffeic acid phenethyl ester results in increased expression of RARA protein [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA mRNA; [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA protein; caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased activity of RARA protein]
CTD
PMID:16766008
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
G
Rb1
RB transcriptional corepressor 1
decreases expression
EXP
caffeic acid phenethyl ester results in decreased expression of RB1 protein modified form
CTD
PMID:15885897
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
G
Rcan1
regulator of calcineurin 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of RCAN1 mRNA
CTD
PMID:20360939
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO EXP
caffeic acid phenethyl ester inhibits the reaction [Paclitaxel results in increased activity of RELA protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased activity of RELA protein]; caffeic acid phenethyl ester results in decreased activity of [NFKB1 protein binds to RELA protein] caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased activity of [NFKB1 protein binds to RELA protein]] caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of RELA protein]
CTD
PMID:11259437 PMID:15291876 PMID:16052512 PMID:26562779 PMID:34789018
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
G
Rem2
RRAD and GEM like GTPase 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of REM2 mRNA
CTD
PMID:20360939
NCBI chr15:31,903,972...31,908,451
Ensembl chr15:31,903,965...31,908,445
G
Ret
ret proto-oncogene
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RET mRNA
CTD
PMID:20360939
NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556
G
Retn
resistin
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of RETN protein
CTD
PMID:21467634
NCBI chr12:6,508,653...6,511,115
Ensembl chr12:6,508,801...6,511,116
G
Rfc1
replication factor C subunit 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RFC1 mRNA
CTD
PMID:20360939
NCBI chr14:43,319,768...43,395,028
Ensembl chr14:43,319,935...43,395,026
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Rgs6
regulator of G-protein signaling 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RGS6 mRNA
CTD
PMID:20360939
NCBI chr 6:107,875,883...108,527,472
Ensembl chr 6:107,876,039...108,555,840
G
Rhob
ras homolog family member B
multiple interactions increases expression
EXP
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of RHOB protein]
CTD
PMID:20836997
NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
G
Rpe65
retinoid isomerohydrolase RPE65
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPE65 mRNA
CTD
PMID:20360939
NCBI chr 2:251,425,228...251,457,209
Ensembl chr 2:251,425,368...251,457,156
G
Rph3a
rabphilin 3A
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPH3A mRNA
CTD
PMID:20360939
NCBI chr12:41,203,004...41,279,536
Ensembl chr12:41,200,089...41,279,531
G
Rpl26
ribosomal protein L26
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of RPL26 mRNA]
CTD
PMID:20360939
NCBI chr10:54,109,692...54,112,822
Ensembl chr10:54,109,362...54,112,822
G
Rps3a
ribosomal protein S3a
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPS3A mRNA
CTD
PMID:20360939
NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
G
Rps6ka2
ribosomal protein S6 kinase A2
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Mustard Compounds results in increased phosphorylation of RPS6KA2 protein]; caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of RPS6KA2 protein]
CTD
PMID:17204746
NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338
G
Rps9
ribosomal protein S9
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPS9 mRNA
CTD
PMID:20360939
NCBI chr 1:74,427,084...74,430,513
Ensembl chr 1:74,427,087...74,430,105
G
RT1-A3
RT1 class I, locus A3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RT1-A3 mRNA
CTD
PMID:20360939
NCBI chr20:4,849,410...4,853,233
G
RT1-N1
RT1 class Ib, locus N1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RT1-N1 mRNA
CTD
PMID:20360939
G
RT1-S3
RT1 class Ib, locus S3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RT1-S3 mRNA; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of RT1-S3 mRNA
CTD
PMID:20360939
NCBI chr20:2,675,463...2,680,229
G
Runx2
RUNX family transcription factor 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein]
CTD
PMID:28363435
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
G
S100b
S100 calcium binding protein B
increases expression multiple interactions
EXP
caffeic acid phenethyl ester results in increased expression of S100B protein NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of S100B protein]
CTD
PMID:20836997
NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081
G
Scaper
S-phase cyclin A-associated protein in the ER
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SCAPER mRNA
CTD
PMID:20360939
NCBI chr 8:64,828,789...65,228,240
Ensembl chr 8:64,828,789...65,228,453
G
Scd
stearoyl-CoA desaturase
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of SCD1 mRNA]
CTD
PMID:20360939
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
G
Scnn1g
sodium channel epithelial 1 subunit gamma
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of SCNN1G mRNA]
CTD
PMID:20360939
NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:185,736,191...185,770,097
G
Sdc4
syndecan 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of SDC4 mRNA
CTD
PMID:20360939
NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670
G
Sds
serine dehydratase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SDS mRNA
CTD
PMID:20360939
NCBI chr12:41,743,796...41,751,108
Ensembl chr12:41,743,799...41,748,773
G
Serpina3c
serine (or cysteine) proteinase inhibitor, clade A, member 3C
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINA3K mRNA
CTD
PMID:20360939
NCBI chr 6:129,007,578...129,014,988
Ensembl chr 6:128,829,577...129,014,971
G
Serpinb2
serpin family B member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINB2 mRNA
CTD
PMID:20360939
NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031
G
Serpinb5
serpin family B member 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINB5 mRNA
CTD
PMID:20360939
NCBI chr13:23,500,203...23,520,401
Ensembl chr13:23,500,198...23,520,400
G
Serpinf1
serpin family F member 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINF1 mRNA
CTD
PMID:20360939
NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898
G
Sirt2
sirtuin 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SIRT2 mRNA
CTD
PMID:20360939
NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499
G
Slc12a8
solute carrier family 12, member 8
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC12A8 mRNA
CTD
PMID:20360939
NCBI chr11:80,622,000...80,771,674
Ensembl chr11:80,622,000...80,771,659
G
Slc14a2
solute carrier family 14 member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC14A2 mRNA
CTD
PMID:20360939
Ensembl chr18:73,887,575...73,953,570
G
Slc17a8
solute carrier family 17 member 8
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC17A8 mRNA]
CTD
PMID:20360939
NCBI chr 7:25,881,557...25,936,837
Ensembl chr 7:25,881,557...25,935,410
G
Slc1a1
solute carrier family 1 member 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC1A1 mRNA
CTD
PMID:20360939
NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469
G
Slc1a5
solute carrier family 1 member 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC1A5 mRNA
CTD
PMID:20360939
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
G
Slc38a2
solute carrier family 38, member 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC38A2 mRNA
CTD
PMID:20360939
NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619
G
Slc45a1
solute carrier family 45, member 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC45A1 mRNA
CTD
PMID:20360939
NCBI chr 5:166,388,115...166,412,183
Ensembl chr 5:166,388,115...166,412,183
G
Slc4a2
solute carrier family 4 member 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC4A2 mRNA]
CTD
PMID:20360939
NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:11,628,862...11,645,402
G
Slc51a
solute carrier family 51 member A
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51A mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51A mRNA]
CTD
PMID:28223344
NCBI chr11:81,804,141...81,818,539
Ensembl chr11:81,803,972...81,818,539
G
Slc51b
SLC51 subunit beta
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51B mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51B mRNA]
CTD
PMID:28223344
NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:74,827,047...74,835,109
G
Slc6a9
solute carrier family 6 member 9
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC6A9 mRNA
CTD
PMID:20360939
NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172
G
Smpd3
sphingomyelin phosphodiesterase 3
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA]
CTD
PMID:28223344
NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936
G
Smpd4
sphingomyelin phosphodiesterase 4
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA]
CTD
PMID:28223344
NCBI chr11:96,866,805...96,890,520
Ensembl chr11:96,866,805...96,890,520
G
Snd1
staphylococcal nuclease and tudor domain containing 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of SND1 mRNA
CTD
PMID:20360939
NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:58,060,640...58,459,925
G
Soat1
sterol O-acyltransferase 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SOAT1 mRNA
CTD
PMID:20360939
NCBI chr13:71,105,178...71,147,776
Ensembl chr13:71,105,178...71,147,672
G
Sod1
superoxide dismutase 1
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in decreased expression of SOD1 protein]
CTD
PMID:22692362
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
G
Sox10
SRY-box transcription factor 10
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SOX10 mRNA
CTD
PMID:20360939
NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:112,605,721...112,615,990
G
Spa17
sperm autoantigenic protein 17
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SPA17 mRNA
CTD
PMID:20360939
NCBI chr 8:45,496,175...45,507,262
Ensembl chr 8:45,496,175...45,507,262
G
Sphk1
sphingosine kinase 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SPHK1 mRNA
CTD
PMID:20360939
NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
G
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA]
CTD
PMID:28223344
NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:112,679,623...112,762,640
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Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO EXP
caffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein] caffeic acid phenethyl ester analog affects the expression of and affects the phosphorylation of STAT3 protein caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of STAT3 mRNA]
CTD
PMID:22155090 PMID:32125059 PMID:34789018
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
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Strn
striatin
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of STRN mRNA
CTD
PMID:20360939
NCBI chr 6:22,087,419...22,174,284
Ensembl chr 6:22,087,497...22,193,048
G
Stx2
syntaxin 2
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of STX2 mRNA
CTD
PMID:20360939
NCBI chr12:33,315,447...33,350,788
Ensembl chr12:33,315,750...33,350,788
G
Sult2a6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SULT2A6 mRNA
CTD
PMID:20360939
NCBI chr 1:84,046,685...84,097,808
Ensembl chr 1:84,046,685...84,097,808
G
Tec
tec protein tyrosine kinase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TEC mRNA
CTD
PMID:20360939
NCBI chr14:35,706,557...35,815,563
Ensembl chr14:35,691,741...35,815,585
G
Tg
thyroglobulin
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TG mRNA
CTD
PMID:20360939
NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:100,307,349...100,314,539 Ensembl chr 7:100,307,349...100,314,539
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Tgfb2
transforming growth factor, beta 2
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of TGFB2 mRNA]
CTD
PMID:16085347
NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856
G
Tgm4
transglutaminase 4
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TGM4 mRNA
CTD
PMID:20360939
NCBI chr 8:131,566,887...131,603,920
Ensembl chr 8:131,566,887...131,603,920
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Th
tyrosine hydroxylase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TH mRNA
CTD
PMID:20360939
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
G
Tk1
thymidine kinase 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TK1 mRNA
CTD
PMID:20360939
NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,533,449...103,556,228
G
Tkt
transketolase
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TKT mRNA
CTD
PMID:20360939
NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431
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Tlr4
toll-like receptor 4
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of TLR4 protein]
CTD
PMID:34743973
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
G
Tmod2
tropomodulin 2
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of TMOD2 mRNA]
CTD
PMID:20360939
NCBI chr 8:85,197,222...85,250,627
Ensembl chr 8:85,196,226...85,246,371
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Tnf
tumor necrosis factor
multiple interactions decreases expression
ISO EXP
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased activity of RELA protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of TNF protein] caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased expression of TNF protein] caffeic acid phenethyl ester results in decreased expression of TNF protein caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of TNF protein]
CTD
PMID:10757128 PMID:11259437 PMID:15291876 PMID:16085347 PMID:16271621 PMID:21467634 PMID:21472898 PMID:24224404 PMID:24508943 PMID:26562779 PMID:34743973 PMID:34789018 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfrsf10b
TNF receptor superfamily member 10b
multiple interactions
ISO
[Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of TNFRSF10A mRNA
CTD
PMID:24289642
NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082
G
Tnfrsf11b
TNF receptor superfamily member 11B
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]
CTD
PMID:28363435
NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
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Tnfsf11
TNF superfamily member 11
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased expression of TNFSF11 mRNA]
CTD
PMID:28363435
NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
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Tnnt1
troponin T1, slow skeletal type
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of TNNT1 mRNA]
CTD
PMID:20360939
NCBI chr 1:78,349,035...78,359,394
Ensembl chr 1:78,349,035...78,359,394
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Tp53
tumor protein p53
multiple interactions
ISO EXP
caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of TP53 protein]; caffeic acid phenethyl ester inhibits the reaction [Mustard Compounds results in increased phosphorylation of TP53 protein]; caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of TP53 protein]; caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in decreased expression of TP53 protein] caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA]
CTD
PMID:17204746 PMID:20360939 PMID:22692362 PMID:26056802
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Trim17
tripartite motif-containing 17
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TRIM17 mRNA
CTD
PMID:20360939
NCBI chr10:44,242,688...44,250,504
Ensembl chr10:44,240,184...44,250,494
G
Ttn
titin
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TTN mRNA
CTD
PMID:20360939
NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171
G
Txnl1
thioredoxin-like 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TXNL1 mRNA
CTD
PMID:20360939
NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518
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Tyr
tyrosinase
multiple interactions affects response to substance increases oxidation
ISO
[TYR protein affects the susceptibility to caffeic acid phenethyl ester] which affects the abundance of Glutathione; [TYR protein affects the susceptibility to caffeic acid phenethyl ester] which affects the abundance of Reactive Oxygen Species; ethylenediamine inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid]; ethylenediamine inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD]; ethylenediamine inhibits the reaction [TYR protein results in increased oxidation of caffeic acid phenethyl ester]; Glutathione inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid]; Glutathione inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD]; Glutathione inhibits the reaction [TYR protein results in increased oxidation of caffeic acid phenethyl ester]; TYR protein results in increased metabolism of and results in increased susceptibility to caffeic acid phenethyl ester [TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid; [TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD; TYR protein results in increased oxidation of caffeic acid phenethyl ester
CTD
PMID:20685355 PMID:21458432
NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
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Vamp8
vesicle-associated membrane protein 8
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VAMP8 mRNA
CTD
PMID:20360939
NCBI chr 4:106,000,570...106,011,081
Ensembl chr 4:106,000,570...106,011,073
G
Vcam1
vascular cell adhesion molecule 1
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
CTD
PMID:16271621
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
G
Vcpip1
valosin containing protein interacting protein 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VCPIP1 mRNA
CTD
PMID:20360939
NCBI chr 5:14,317,083...14,343,724
Ensembl chr 5:14,316,918...14,347,778
G
Vdac1
voltage-dependent anion channel 1
multiple interactions
ISO
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA]
CTD
PMID:28223344
NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
G
Vegfa
vascular endothelial growth factor A
multiple interactions
ISO
caffeic acid phenethyl ester inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VEGFA protein]
CTD
PMID:34791780
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
G
Vtn
vitronectin
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VTN mRNA
CTD
PMID:20360939
NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860
G
Vwf
von Willebrand factor
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VWF mRNA
CTD
PMID:20360939
NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757
G
Wrnip1
WRN helicase interacting protein 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of WRNIP1 mRNA
CTD
PMID:20360939
NCBI chr17:31,830,159...31,850,408
Ensembl chr17:31,830,160...31,850,408
G
Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
caffeic acid phenethyl ester results in decreased expression of XIAP protein
CTD
PMID:15291876
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978
G
Xrcc5
X-ray repair cross complementing 5
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of XRCC5 mRNA
CTD
PMID:20360939
NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293
G
Ybx3
Y box binding protein 3
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of YBX3 mRNA
CTD
PMID:20360939
NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691
G
Yy1
YY1 transcription factor
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of YY1 mRNA]
CTD
PMID:20360939
NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:133,471,562...133,497,257
G
Zfp180
zinc finger protein 180
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZFP180 mRNA
CTD
PMID:20360939
NCBI chr 1:88,780,342...88,800,637
Ensembl chr 1:88,780,342...88,800,627
G
Zfp37
zinc finger protein 37
multiple interactions
EXP
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP37 mRNA]
CTD
PMID:20360939
NCBI chr 5:80,600,463...80,656,064
Ensembl chr 5:80,600,463...80,654,404
G
Zfp384
zinc finger protein 384
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZFP384 mRNA
CTD
PMID:20360939
NCBI chr 4:159,496,481...159,526,010
Ensembl chr 4:159,496,729...159,526,010
G
Zfp394
zinc finger protein 394
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZNF394 mRNA
CTD
PMID:20360939
NCBI chr12:14,522,820...14,530,998
G
Zhx1
zinc fingers and homeoboxes 1
multiple interactions
EXP
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZHX1 mRNA
CTD
PMID:20360939
NCBI chr 7:91,472,193...91,501,984
Ensembl chr 7:91,473,836...91,501,115
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