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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:caffeic acid
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Accession:CHEBI:36281 term browser browse the term
Definition:A hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common.
Synonyms:exact_synonym: 3-(3,4-dihydroxyphenyl)prop-2-enoic acid
 related_synonym: Formula=C9H8O4;   InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13);   InChIKey=QAIPRVGONGVQAS-UHFFFAOYSA-N;   SMILES=OC(=O)C=Cc1ccc(O)c(O)c1
 xref: Beilstein:2210883;   HMDB:HMDB0001964;   KEGG:C01481;   LINCS:LSM-5272;   PMID:11373473;   PMID:15778121;   PMID:18061431;   PMID:18314336;   PMID:18482095;   PMID:20542693;   PMID:8340025;   Reaxys:2210883



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acteoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle decreases expression ISO acteoside results in decreased expression of ACTA2 protein CTD PMID:33522686 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases expression ISO acteoside results in decreased expression of AGER protein CTD PMID:33522686 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases localization
ISO acteoside promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]
acteoside results in decreased localization of AHR protein
CTD PMID:21756928 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases localization ISO acteoside results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
decreases secretion
ISO acteoside results in decreased expression of CCL2 mRNA
acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
acteoside results in decreased secretion of CCL2 protein
CTD PMID:21756928 PMID:21967610 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO acteoside results in decreased expression of CCND1 protein CTD PMID:17634406 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO acteoside results in decreased expression of CCND2 protein CTD PMID:17634406 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO acteoside results in decreased expression of CCND3 protein CTD PMID:17634406 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO acteoside results in decreased expression of CCNE1 protein CTD PMID:17634406 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdh1 cadherin 1 increases expression ISO acteoside results in increased expression of CDH1 protein CTD PMID:33522686 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO acteoside results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:17634406 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity
multiple interactions
ISO acteoside results in decreased activity of CDK4 protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]
CTD PMID:17634406 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]; acteoside results in decreased expression of and results in decreased activity of CDK6 protein CTD PMID:17634406 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO acteoside results in increased expression of CDKN1A mRNA; acteoside results in increased expression of CDKN1A protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]
CTD PMID:17634406 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO acteoside results in increased expression of CDKN1B mRNA; acteoside results in increased expression of CDKN1B protein
acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]
CTD PMID:17634406 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases secretion
decreases expression
multiple interactions
ISO acteoside results in decreased secretion of CXCL10 protein
acteoside results in decreased expression of CXCL10 mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [PD168393 results in increased secretion of CXCL10 protein]; acteoside promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein]
CTD PMID:21756928 PMID:21967610 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO acteoside results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:14672760 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein] CTD PMID:17634406 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation
multiple interactions
ISO acteoside results in decreased phosphorylation of EGFR protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein]
CTD PMID:21756928 PMID:21967610 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression ISO acteoside results in decreased expression of HMGB1 protein CTD PMID:33522686 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO acteoside results in decreased expression of ICAM1 mRNA CTD PMID:21371465 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
ISO acteoside results in decreased expression of IFNG mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
CTD PMID:21371465 PMID:21756928 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
acteoside results in decreased expression of IL6 mRNA
CTD PMID:21756928 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO acteoside inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] CTD PMID:16393473 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
decreases phosphorylation
ISO acteoside results in increased phosphorylation of MAPK1 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]
acteoside results in decreased phosphorylation of MAPK1 protein
CTD PMID:21756928 PMID:23527233 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO acteoside results in decreased phosphorylation of MAPK3 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]
acteoside results in increased phosphorylation of MAPK3 protein
CTD PMID:21756928 PMID:23527233 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nox1 NADPH oxidase 1 decreases activity ISO acteoside results in decreased activity of NOX1 protein CTD PMID:16393473 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO acteoside binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [acteoside co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA CTD PMID:21756928 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO Verbascoside decreases expression of RAC1 mRNA in colon cancer cells RGD PMID:29886834 RGD:153298971 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation
multiple interactions
ISO acteoside results in decreased phosphorylation of RB1 protein
[acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein]
CTD PMID:17634406 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
decreases phosphorylation
ISO acteoside results in increased phosphorylation of RELA protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
acteoside results in decreased phosphorylation of RELA protein
CTD PMID:21756928 PMID:23527233 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation ISO acteoside results in increased phosphorylation of SMAD2 protein CTD PMID:17634406 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 increases phosphorylation ISO acteoside results in increased phosphorylation of SMAD3 protein CTD PMID:17634406 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad7 SMAD family member 7 increases expression ISO acteoside results in increased expression of SMAD7 protein CTD PMID:33522686 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO acteoside results in decreased expression of SNAI1 protein CTD PMID:33522686 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO acteoside results in decreased expression of SNAI2 protein CTD PMID:33522686 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO acteoside results in decreased expression of SOD2 mRNA CTD PMID:21371465 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO [acteoside co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21756928 PMID:21967610 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO acteoside results in increased expression of TGFB1 mRNA CTD PMID:17634406 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO acteoside results in decreased expression of TGFBR1 protein CTD PMID:33522686 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 decreases expression ISO acteoside results in decreased expression of TGFBR2 protein CTD PMID:33522686 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO acteoside results in decreased expression of VCAM1 mRNA CTD PMID:21371465 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
chlorogenic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC1 protein] CTD PMID:25043994 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein] CTD PMID:25043994 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Ache acetylcholinesterase decreases activity ISO Chlorogenic Acid results in decreased activity of ACHE protein CTD PMID:20854806 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase increases expression ISO Chlorogenic Acid results in increased expression of ACLY mRNA CTD PMID:20706672 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:23146752 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Rotenone results in decreased phosphorylation of AKT1 protein] CTD PMID:36048341 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]
Chlorogenic Acid affects the reaction [2,2'-azobis(2-amidinopropane) results in increased degradation of ALB protein]
CTD PMID:11322927 PMID:23146752 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Chlorogenic Acid results in increased expression of AQP1 mRNA CTD PMID:20706672 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Chlorogenic Acid results in increased expression of AQP3 mRNA CTD PMID:20706672 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Ar androgen receptor decreases expression ISO Chlorogenic Acid results in decreased expression of AR mRNA CTD PMID:20706672 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ATF4 protein] CTD PMID:34801538 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ATF6 protein] CTD PMID:34801538 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions EXP Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAMBI mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAMBI protein] CTD PMID:23146752 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
Chlorogenic Acid inhibits the reaction [Aluminum Chloride results in increased expression of BAX protein]; Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of BAX mRNA]
Chlorogenic Acid results in increased expression of BAX mRNA; Chlorogenic Acid results in increased expression of BAX protein
Chlorogenic Acid inhibits the reaction [Methotrexate results in increased expression of BAX protein]
CTD PMID:25043994 PMID:28479099 PMID:28623112 PMID:33058431 PMID:33242462 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
Chlorogenic Acid inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]
Chlorogenic Acid results in decreased expression of BCL2 mRNA; Chlorogenic Acid results in decreased expression of BCL2 protein
Chlorogenic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of BCL2 protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of BCL2 mRNA]
CTD PMID:28479099 PMID:28623112 PMID:33058431 PMID:33242462 PMID:34801538 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Canx calnexin multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CANX protein] CTD PMID:34801538 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp12 caspase 12 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CASP12 protein] CTD PMID:34801538 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO
EXP
Chlorogenic Acid inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
Chlorogenic Acid results in increased expression of CASP3 mRNA
Chlorogenic Acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased activity of CASP3 protein]
CTD PMID:25043994 PMID:28479099 PMID:33058431 PMID:33242462 PMID:34801538 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Chlorogenic Acid inhibits the reaction [aluminum chloride results in increased expression of CASP8 protein] CTD PMID:28623112 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Methotrexate results in increased activity of CASP9 protein] CTD PMID:28479099 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in decreased activity of CAT protein]
Chlorogenic Acid inhibits the reaction [Aluminum Chloride results in decreased activity of CAT protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of CAT mRNA]
CTD PMID:28479099 PMID:28623112 PMID:31390532 PMID:33242462 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of CCL2 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of CCL2 protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:26079055 PMID:31306686 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CCND1 protein] CTD PMID:25043994 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd44 CD44 molecule increases expression ISO Chlorogenic Acid results in increased expression of CD44 mRNA CTD PMID:20706672 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Chlorogenic Acid results in increased expression of CDH1 mRNA CTD PMID:20706672 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO
EXP
Chlorogenic Acid results in increased expression of COL1A1 mRNA
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]
CTD PMID:20706672 PMID:23146752 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Cs citrate synthase increases activity ISO Chlorogenic Acid results in increased activity of CS protein CTD PMID:31306686 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of CXCL1 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of CXCL1 protein] CTD PMID:26079055 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cygb cytoglobin decreases expression ISO Chlorogenic Acid results in decreased expression of CYGB mRNA CTD PMID:20706672 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP Chlorogenic Acid results in increased expression of CYP19A1 protein CTD PMID:29899696 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] CTD PMID:25043994 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of DDIT3 protein] CTD PMID:34801538 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dsg3 desmoglein 3 decreases expression ISO Chlorogenic Acid results in decreased expression of DSG3 mRNA CTD PMID:20706672 NCBI chr18:11,799,355...11,830,988
Ensembl chr18:11,798,900...11,830,818
JBrowse link
G Egf epidermal growth factor decreases expression ISO Chlorogenic Acid results in decreased expression of EGF mRNA CTD PMID:20706672 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of EIF2AK3 protein] CTD PMID:34801538 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein] CTD PMID:34801538 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] CTD PMID:34801538 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ERO1A protein] CTD PMID:34801538 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP Chlorogenic Acid results in decreased expression of ESR1 protein CTD PMID:29899696 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases expression EXP Chlorogenic Acid results in increased expression of ESR2 protein CTD PMID:29899696 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G F10 coagulation factor X decreases activity ISO Chlorogenic Acid results in decreased activity of F10 protein CTD PMID:27704645 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2 coagulation factor II, thrombin decreases activity ISO Chlorogenic Acid results in decreased activity of F2 protein CTD PMID:27704645 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Chlorogenic Acid results in decreased expression of FASN mRNA CTD PMID:21870829 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO Chlorogenic Acid results in decreased expression of FBN1 mRNA CTD PMID:20706672 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO Chlorogenic Acid results in decreased expression of FBN2 mRNA CTD PMID:20706672 NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Ffar1 free fatty acid receptor 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Rotenone results in decreased expression of FFAR1 mRNA] CTD PMID:36048341 NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272
JBrowse link
G Ffar2 free fatty acid receptor 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Rotenone results in decreased expression of FFAR2 mRNA] CTD PMID:36048341 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Chlorogenic Acid results in increased expression of FGF1 mRNA CTD PMID:20706672 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of FSHB protein] CTD PMID:33242462 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression EXP Chlorogenic Acid results in increased expression of FSHR protein CTD PMID:29899696 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Gcg glucagon multiple interactions ISO [Chlorogenic Acid co-treated with Rotenone] results in increased secretion of GCG protein CTD PMID:36048341 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO Chlorogenic Acid results in increased expression of GCLC mRNA
Chlorogenic Acid promotes the reaction [Acetaminophen results in increased expression of GCLC mRNA]
CTD PMID:29136249 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Chlorogenic Acid results in increased expression of GCLM mRNA CTD PMID:29136249 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions ISO Chlorogenic Acid inhibits the reaction [Rotenone results in decreased expression of GLP1R protein] CTD PMID:36048341 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
decreases expression
EXP
ISO
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of GPT protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased activity of GPT protein]
Chlorogenic Acid results in decreased expression of GPT protein
Chlorogenic Acid inhibits the reaction [aluminum chloride results in increased activity of GPT protein]
CTD PMID:28479099 PMID:28623112 PMID:31390532 PMID:33058431 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA] CTD PMID:33242462 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grn granulin precursor increases expression ISO Chlorogenic Acid results in increased expression of GRN mRNA CTD PMID:20706672 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Chlorogenic Acid inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein] CTD PMID:36048341 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Methotrexate results in decreased activity of GSR protein]
Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of GSR mRNA]
CTD PMID:28479099 PMID:33242462 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases activity ISO Chlorogenic Acid results in increased activity of GSTA1 protein CTD PMID:15944151 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Has1 hyaluronan synthase 1 increases expression ISO Chlorogenic Acid results in increased expression of HAS1 mRNA CTD PMID:20706672 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Chlorogenic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases expression
EXP
ISO
[tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]
Chlorogenic Acid results in decreased expression of HMGCR mRNA
CTD PMID:20696151 PMID:21870829 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of HMOX1 protein]
Chlorogenic Acid results in increased expression of HMOX1 mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein]
CTD PMID:25043994 PMID:29136249 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of HSPA5 protein] CTD PMID:34801538 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Chlorogenic Acid results in increased expression of HSPB1 mRNA CTD PMID:20706672 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Chlorogenic Acid results in decreased expression of IL1A mRNA CTD PMID:20706672 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of IL1B protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
CTD PMID:23146752 PMID:24709313 PMID:26079055 PMID:33242462 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Chlorogenic Acid results in increased expression of IL6 mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of IL6 protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL6 protein]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]
CTD PMID:21870829 PMID:23146752 PMID:26079055 PMID:31390532 PMID:33242462 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
multiple interactions
EXP Chlorogenic Acid results in decreased expression of ITGB2 protein
Chlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of ITGB2 protein]
CTD PMID:21414398 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein] CTD PMID:15944151 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Krt5 keratin 5 increases expression ISO Chlorogenic Acid results in increased expression of KRT5 mRNA CTD PMID:20706672 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein] CTD PMID:20696151 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of LHB protein] CTD PMID:33242462 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein] CTD PMID:20696151 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO Chlorogenic Acid results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity ISO Chlorogenic Acid results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein] CTD PMID:15944151 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
Chlorogenic Acid promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK1 protein]
CTD PMID:15944151 PMID:29136249 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein] CTD PMID:15944151 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
Chlorogenic Acid promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK3 protein]
CTD PMID:15944151 PMID:29136249 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein] CTD PMID:34801538 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mc1r melanocortin 1 receptor increases expression ISO Chlorogenic Acid results in increased expression of MC1R mRNA CTD PMID:20706672 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Chlorogenic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of MPO protein] CTD PMID:26079055 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression ISO Chlorogenic Acid results in increased expression of COX1 mRNA CTD PMID:20706672 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [Chlorogenic Acid co-treated with Zymosan] results in decreased expression of COX2 protein; Chlorogenic Acid inhibits the reaction [Zymosan results in increased expression of COX2 protein] CTD PMID:30481570 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of MYD88 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of MYD88 protein]
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of MYD88 protein]
CTD PMID:23146752 PMID:26079055 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases localization
multiple interactions
increases response to substance
affects localization
decreases response to substance
ISO Chlorogenic Acid results in increased localization of NFE2L2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Chlorogenic Acid co-treated with Acetaminophen] results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein]; [Chlorogenic Acid co-treated with Acetaminophen] results in increased activity of and affects the localization of NFE2L2 protein; [Chlorogenic Acid co-treated with Acetaminophen] results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein; U 0126 inhibits the reaction [[Chlorogenic Acid co-treated with Acetaminophen] results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein]
[Chlorogenic Acid co-treated with Acetaminophen] affects the localization of and results in increased activity of NFE2L2 protein; Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of NFE2L2 mRNA]
NFE2L2 results in increased susceptibility to Chlorogenic Acid
Chlorogenic Acid affects the localization of NFE2L2 protein
NFE2L2 gene mutant form results in decreased susceptibility to Chlorogenic Acid
CTD PMID:15944151 PMID:29136249 PMID:33242462 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:20026373 PMID:23146752 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein] CTD PMID:20026373 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Chlorogenic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of NOS2 mRNA]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased expression of NOS2 protein]
CTD PMID:20026373 PMID:23146752 PMID:28479099 PMID:31306686 PMID:33242462 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO Chlorogenic Acid results in increased expression of NOS3 mRNA CTD PMID:20706672 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein] CTD PMID:34801538 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
multiple interactions
ISO Chlorogenic Acid results in increased activity of NQO1 protein
Chlorogenic Acid results in increased expression of NQO1 mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of NQO1 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of NQO1 protein]
CTD PMID:15944151 PMID:29136249 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression
increases activity
ISO Chlorogenic Acid results in increased expression of NR1H4 mRNA
Chlorogenic Acid results in increased activity of NR1H4 protein
CTD PMID:36542898 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Ocln occludin multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of OCLN mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of OCLN protein] CTD PMID:31390532 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of P4HB protein] CTD PMID:34801538 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Chlorogenic Acid promotes the reaction [Cisplatin results in increased expression of PCNA protein] CTD PMID:25043994 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PECAM1 protein] CTD PMID:21414398 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pgr progesterone receptor increases expression
decreases expression
ISO Chlorogenic Acid results in increased expression of PGR mRNA
Chlorogenic Acid results in decreased expression of PGR mRNA
CTD PMID:20706672 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression
multiple interactions
ISO Chlorogenic Acid results in increased expression of PIK3R1 mRNA
Chlorogenic Acid inhibits the reaction [Rotenone results in decreased phosphorylation of PIK3R1 protein]
CTD PMID:21870829 PMID:36048341 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 increases expression ISO Chlorogenic Acid results in increased expression of PLOD3 mRNA CTD PMID:20706672 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression
ISO Chlorogenic Acid results in increased expression of PPARG mRNA
Chlorogenic Acid results in decreased expression of PPARG mRNA
CTD PMID:20706672 PMID:21870829 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha multiple interactions ISO [Chlorogenic Acid co-treated with Acetaminophen] results in decreased expression of PPP2R1A protein CTD PMID:29136249 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO [Chlorogenic Acid co-treated with Acetaminophen] results in decreased expression of PPP5C protein CTD PMID:29136249 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased expression of PTGS2 protein]
Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]
CTD PMID:20026373 PMID:23146752 PMID:25043994 PMID:28479099 PMID:31306686 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Chlorogenic Acid results in decreased expression of RAD23A mRNA CTD PMID:20706672 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Chlorogenic Acid results in increased expression of RARA mRNA CTD PMID:20706672 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of and results in increased phosphorylation of and affects the localization of RELA protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein] CTD PMID:20026373 PMID:26079055 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Retreg1 reticulophagy regulator 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in decreased expression of RETREG1 protein] CTD PMID:34801538 NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898
JBrowse link
G Rtn3 reticulon 3 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of RTN3 protein] CTD PMID:34801538 NCBI chr 1:204,612,675...204,669,212
Ensembl chr 1:204,612,675...204,669,275
JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Chlorogenic Acid results in decreased expression of RXRA mRNA CTD PMID:20706672 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of SEC62 protein] CTD PMID:34801538 NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
JBrowse link
G Sell selectin L multiple interactions EXP [Chlorogenic Acid co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of SELL protein; Chlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in decreased expression of SELL protein] CTD PMID:21414398 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC11A2 mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC11A2 protein] CTD PMID:31390532 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in decreased expression of SLC22A2 protein] CTD PMID:25043994 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Chlorogenic Acid results in increased expression of SLC2A4 mRNA CTD PMID:21870829 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Snca synuclein alpha multiple interactions ISO Chlorogenic Acid inhibits the reaction [Rotenone results in increased expression of SNCA protein]; Chlorogenic Acid inhibits the reaction [Rotenone results in increased phosphorylation of SNCA protein] CTD PMID:36048341 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
ISO Chlorogenic Acid results in increased expression of SOD2 mRNA
Chlorogenic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA]
CTD PMID:33242462 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Chlorogenic Acid results in decreased expression of SOD3 mRNA CTD PMID:20706672 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] CTD PMID:29136249 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO Chlorogenic Acid results in decreased expression of SRD5A2 mRNA CTD PMID:20706672 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP Chlorogenic Acid results in increased expression of STAR protein CTD PMID:29899696 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TJP1 mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TJP1 protein] CTD PMID:31390532 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR3 protein] CTD PMID:26079055 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR4 protein]
CTD PMID:23146752 PMID:26079055 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO
EXP
Chlorogenic Acid results in increased expression of TNF mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of TNF protein]; Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Chlorogenic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TNF protein]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]
CTD PMID:21870829 PMID:23146752 PMID:25043994 PMID:26079055 PMID:31306686 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of TRP53 protein]
Chlorogenic Acid results in increased expression of TRP53 mRNA
CTD PMID:25043994 PMID:33058431 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression ISO Chlorogenic Acid results in increased expression of TPT1 mRNA CTD PMID:20706672 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
JBrowse link
G Traf2 Tnf receptor-associated factor 2 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of TRAF2 protein] CTD PMID:34801538 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Chlorogenic Acid results in increased expression of TXN mRNA CTD PMID:20706672 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Tyr tyrosinase increases oxidation
multiple interactions
ISO TYR protein results in increased oxidation of Chlorogenic Acid
[TYR protein results in increased oxidation of Chlorogenic Acid] which results in decreased abundance of Glutathione
CTD PMID:20685355 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO Chlorogenic Acid results in decreased expression of TYRP1 mRNA CTD PMID:20706672 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO Chlorogenic Acid results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation
decreases activity
ISO UGT1A3 protein results in increased glucuronidation of Chlorogenic Acid
Chlorogenic Acid results in decreased activity of UGT1A3 protein
CTD PMID:15117964 PMID:35868516 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO Chlorogenic Acid results in decreased activity of UGT1A6 protein CTD PMID:35868516 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO Chlorogenic Acid results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO Chlorogenic Acid results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO Chlorogenic Acid results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of XBP1 mRNA] CTD PMID:34801538 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
cis-caffeic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO caffeic acid results in increased phosphorylation of and results in decreased activity of ACACA protein CTD PMID:28576465 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
EXP caffeic acid inhibits the reaction [Caffeine results in decreased activity of ACHE protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of ACHE protein] CTD PMID:28465162 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of ACLY protein CTD PMID:28576465 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions
decreases activity
ISO [caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]; [caffeic acid results in decreased activity of ALOX15 protein] which results in decreased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [caffeic acid results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; caffeic acid inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of ALOX15 protein] CTD PMID:10904086 PMID:11406566 PMID:15574791 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 protein]; caffeic acid inhibits the reaction [Hydrogen Peroxide affects the localization of ALOX5 protein]
caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 protein]
CTD PMID:18482095 PMID:18951527 PMID:27368151 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein modified form]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein] CTD PMID:18482095 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arg1 arginase 1 decreases activity ISO caffeic acid results in decreased activity of ARG1 protein CTD PMID:27378625 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA] CTD PMID:19442820 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
[caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of CASP3 protein]
CTD PMID:15574791 PMID:29968957 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP
ISO
caffeic acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Nickel results in decreased activity of CAT protein]
caffeic acid results in increased activity of CAT protein
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
CTD PMID:18405891 PMID:21640567 PMID:22036979 PMID:27378625 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL2 mRNA; caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:16806235 PMID:31306686 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL3 mRNA CTD PMID:16806235 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL4 mRNA CTD PMID:16806235 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR1 mRNA CTD PMID:16806235 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR2 mRNA CTD PMID:16806235 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR4 mRNA CTD PMID:16806235 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD4 mRNA CTD PMID:16806235 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD68 mRNA CTD PMID:16806235 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA CTD PMID:19442820 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] CTD PMID:19442820 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO caffeic acid inhibits the reaction [aluminum chloride results in decreased expression of CHAT protein] CTD PMID:18482095 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of caffeic acid CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:25404496 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA] CTD PMID:19442820 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Ctsb cathepsin B multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein] CTD PMID:20391626 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:20391626 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA] CTD PMID:19442820 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dap death-associated protein multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA] CTD PMID:19442820 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA] CTD PMID:19442820 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA] CTD PMID:19442820 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA CTD PMID:16806235 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO caffeic acid affects the reaction [Acetaminophen results in increased expression of and affects the localization of EGR1 protein]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of EGR1 mRNA] CTD PMID:27720869 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elmo2 engulfment and cell motility 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA] CTD PMID:19442820 NCBI chr 3:154,023,661...154,061,259
Ensembl chr 3:154,023,661...154,061,185
JBrowse link
G Erf Ets2 repressor factor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA] CTD PMID:19442820 NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of F3 protein] CTD PMID:27720869 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
ISO caffeic acid results in decreased expression of FASN mRNA
[Metformin co-treated with caffeic acid] results in decreased expression of FASN protein
CTD PMID:21870829 PMID:28576465 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA] CTD PMID:19442820 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA] CTD PMID:19442820 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO caffeic acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A mRNA]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A protein] CTD PMID:27720869 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein] CTD PMID:20391626 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gls glutaminase increases expression ISO caffeic acid results in increased expression of GLS protein CTD PMID:28576465 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15212457 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein]
caffeic acid inhibits the reaction [Acetaminophen results in increased activity of GPT protein]
CTD PMID:15212457 PMID:27720869 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]
CTD PMID:19442820 PMID:21640567 PMID:22036979 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity EXP caffeic acid results in decreased activity of GSTM1 protein CTD PMID:8340025 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases activity EXP caffeic acid results in decreased activity of GSTM2 protein CTD PMID:8340025 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity EXP caffeic acid results in decreased activity of GSTP1 protein CTD PMID:8340025 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:20391626 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions EXP caffeic acid inhibits the reaction [Cisplatin results in decreased activity of H6PD protein] CTD PMID:21640567 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of HAVCR2 mRNA CTD PMID:16806235 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of HES1 mRNA] CTD PMID:29968957 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO caffeic acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO caffeic acid results in decreased expression of HMGCR mRNA CTD PMID:21870829 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA] CTD PMID:19442820 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA] CTD PMID:19442820 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of IFNG protein
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of IFNG protein]
CTD PMID:27378625 PMID:29968957 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 decreases expression ISO caffeic acid results in decreased expression of IL10 protein CTD PMID:27378625 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL1B protein]
CTD PMID:27368151 PMID:27720869 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO caffeic acid results in increased expression of IL2 protein CTD PMID:27378625 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21r interleukin 21 receptor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA] CTD PMID:19442820 NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522
JBrowse link
G Il4 interleukin 4 decreases expression ISO caffeic acid results in decreased expression of IL4 protein CTD PMID:27378625 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of IL6 mRNA
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL6 protein]
CTD PMID:21870829 PMID:27368151 PMID:27720869 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kif15 kinesin family member 15 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of KIF15 mRNA CTD PMID:19442820 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif20b kinesin family member 20B multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA] CTD PMID:19442820 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO caffeic acid inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA] CTD PMID:19442820 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:21472895 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:21472895 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO caffeic acid results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity ISO caffeic acid results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in decreased expression of MAP2K5 mRNA CTD PMID:19442820 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK1 protein] CTD PMID:27720869 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK3 protein] CTD PMID:27720869 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MFN1 mRNA] CTD PMID:19442820 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases activity EXP caffeic acid results in increased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
ISO
EXP
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]
caffeic acid inhibits the reaction [Ethanol results in increased activity of MPO protein]; NG-Nitroarginine Methyl Ester inhibits the reaction [caffeic acid inhibits the reaction [Ethanol results in increased activity of MPO protein]]
caffeic acid results in decreased activity of MPO protein
CTD PMID:22036979 PMID:24060682 PMID:33301711 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRPL45 mRNA] CTD PMID:19442820 NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474
JBrowse link
G Mrrf mitochondrial ribosome recycling factor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA] CTD PMID:19442820 NCBI chr 3:19,487,124...19,543,911
Ensembl chr 3:19,487,182...19,543,908
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [caffeic acid co-treated with Zymosan] results in increased expression of COX2 protein; caffeic acid inhibits the reaction [Zymosan results in increased expression of COX2 protein] CTD PMID:30481570 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Ndp norrin cystine knot growth factor NDP increases expression ISO caffeic acid results in increased expression of NDP mRNA CTD PMID:19442820 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOS2 protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:29968957 PMID:31306686 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO caffeic acid results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA] CTD PMID:29968957 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions
decreases activity
EXP caffeic acid inhibits the reaction [Caffeine results in decreased activity of NT5E protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of NT5E protein] CTD PMID:28465162 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Pdcd10 programmed cell death 10 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PDCD10 mRNA] CTD PMID:19442820 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO caffeic acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO caffeic acid results in increased expression of PIK3R1 mRNA CTD PMID:21870829 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of PLK1 mRNA CTD PMID:19442820 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of PLK4 mRNA] CTD PMID:19442820 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO caffeic acid results in increased expression of PPARG mRNA CTD PMID:21870829 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PRDX5 mRNA] CTD PMID:19442820 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTGS2 mRNA]
CTD PMID:19442820 PMID:22036979 PMID:31306686 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTX3 mRNA] CTD PMID:19442820 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of RELA protein] CTD PMID:29968957 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of SCD1 protein CTD PMID:28576465 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein] CTD PMID:27720869 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of SFXN4 mRNA] CTD PMID:19442820 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO caffeic acid results in increased expression of SLC2A2 mRNA CTD PMID:33493636 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO caffeic acid results in increased expression of SLC2A4 mRNA CTD PMID:21870829 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO caffeic acid results in increased expression of SLC5A1 mRNA CTD PMID:33493636 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
JBrowse link
G Snca synuclein alpha multiple interactions ISO caffeic acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stk32a serine/threonine kinase 32A multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in decreased expression of STK32A mRNA CTD PMID:19442820 NCBI chr18:35,258,865...35,374,985
Ensembl chr18:35,259,052...35,369,451
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of caffeic acid CTD PMID:17433394 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases sulfation ISO SULT1C2 protein results in increased sulfation of caffeic acid CTD PMID:17433394 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of TNF mRNA
caffeic acid inhibits the reaction [Aluminum results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Valproic Acid results in increased expression of TNF protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]
CTD PMID:21870829 PMID:22036979 PMID:27368151 PMID:29968957 PMID:31306686 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 affects expression
multiple interactions
ISO caffeic acid affects the expression of TP53 protein
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA]
CTD PMID:11522280 PMID:19442820 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tyr tyrosinase increases oxidation
multiple interactions
ISO TYR protein results in increased oxidation of caffeic acid
[TYR protein results in increased oxidation of caffeic acid] which results in decreased abundance of Glutathione
CTD PMID:20685355 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of UBE2C mRNA] CTD PMID:19442820 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO caffeic acid results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation
decreases activity
ISO UGT1A3 protein results in increased glucuronidation of caffeic acid
caffeic acid results in decreased activity of UGT1A3 protein
CTD PMID:15117964 PMID:35868516 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO caffeic acid results in decreased activity of UGT1A6 protein CTD PMID:35868516 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO caffeic acid results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO caffeic acid results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO caffeic acid results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Vegfa vascular endothelial growth factor A decreases secretion ISO caffeic acid results in decreased secretion of VEGFA protein CTD PMID:27378625 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:22036979 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
ethyl trans-caffeate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO ethyl caffeate affects the phosphorylation of and affects the activity of AKT1 protein CTD PMID:24892518 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Cdh2 cadherin 2 affects expression ISO ethyl caffeate affects the expression of CDH2 protein CTD PMID:24892518 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk2 cyclin dependent kinase 2 affects expression ISO ethyl caffeate affects the expression of CDK2 protein CTD PMID:24892518 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO ethyl caffeate affects the expression of CDK4 protein CTD PMID:24892518 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects expression
multiple interactions
ISO ethyl caffeate affects the expression of ERBB2 protein
ethyl caffeate affects the phosphorylation of and affects the activity of ERBB2 protein
CTD PMID:24892518 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 affects expression ISO ethyl caffeate affects the expression of FGFR1 protein CTD PMID:24892518 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Ilk integrin-linked kinase affects expression ISO ethyl caffeate affects the expression of ILK protein CTD PMID:24892518 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions ISO ethyl caffeate affects the expression of [ITGA3 protein binds to ITGB1 protein] CTD PMID:24892518 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO ethyl caffeate affects the expression of [ITGA3 protein binds to ITGB1 protein] CTD PMID:24892518 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Kdr kinase insert domain receptor affects expression ISO ethyl caffeate affects the expression of KDR protein CTD PMID:24892518 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO ethyl caffeate affects the phosphorylation of and affects the activity of MAPK1 protein CTD PMID:24892518 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO ethyl caffeate affects the phosphorylation of and affects the activity of MAPK3 protein CTD PMID:24892518 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects phosphorylation ISO ethyl caffeate affects the phosphorylation of RB1 protein CTD PMID:24892518 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
methyl caffeate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of AKT1 protein CTD PMID:25481497 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO methyl caffeate results in increased expression of BAX protein CTD PMID:26415618 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO methyl caffeate binds to and results in decreased expression of BCL2 protein CTD PMID:26415618 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO methyl caffeate results in increased expression of BID protein CTD PMID:26415618 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp3 caspase 3 increases activity ISO methyl caffeate results in increased activity of CASP3 protein CTD PMID:26415618 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO methyl caffeate analog results in increased expression of CDKN1A protein CTD PMID:25481497 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO methyl caffeate analog results in decreased expression of KDR protein CTD PMID:25481497 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of MAPK1 protein CTD PMID:25481497 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of MAPK3 protein CTD PMID:25481497 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mdm2 MDM2 proto-oncogene affects binding ISO methyl caffeate binds to MDM2 protein CTD PMID:26415618 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO methyl caffeate analog results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:25481497 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO methyl caffeate analog results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:25481497 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of MTOR protein CTD PMID:25481497 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO methyl caffeate binds to and results in increased activity of PARP1 protein CTD PMID:26415618 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Tp53 tumor protein p53 increases expression ISO methyl caffeate analog results in increased expression of TP53 protein CTD PMID:25481497 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO methyl caffeate analog results in decreased expression of and results in decreased secretion of VEGFA protein CTD PMID:25481497 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
phenethyl caffeate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of A2M mRNA] CTD PMID:20360939 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AANAT mRNA CTD PMID:20360939 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCA5 mRNA CTD PMID:20360939 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO caffeic acid phenethyl ester metabolite results in decreased activity of ABCC1 protein CTD PMID:15885658 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA CTD PMID:20360939 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acan aggrecan multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACAN mRNA CTD PMID:20360939 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACOT2 mRNA CTD PMID:20360939 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of ACP5 protein] CTD PMID:28363435 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Ada adenosine deaminase multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Methotrexate results in increased activity of ADA protein] CTD PMID:16325979 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam7 ADAM metallopeptidase domain 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADAM7 mRNA CTD PMID:20360939 NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201
JBrowse link
G Adcy2 adenylate cyclase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADCY2 mRNA CTD PMID:20360939 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADRA1D mRNA CTD PMID:20360939 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AGAP2 mRNA CTD PMID:20360939 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in decreased expression of AHR protein] CTD PMID:17204746 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA] CTD PMID:16365417 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Akap9 A-kinase anchoring protein 9 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AKAP9 mRNA CTD PMID:20360939 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1B1 protein CTD PMID:27163852 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1B10 protein CTD PMID:27163852 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1C1 protein CTD PMID:27163852 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1C2 protein CTD PMID:27163852 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1C3 protein CTD PMID:27163852 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation ISO caffeic acid phenethyl ester analog affects the phosphorylation of AKT1 protein CTD PMID:32125059 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ALDH1A2 mRNA CTD PMID:20360939 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO
EXP
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of ALPL protein]
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of ALPL protein]
CTD PMID:18436364 PMID:28363435 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Ankrd17 ankyrin repeat domain 17 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ANKRD17 mRNA] CTD PMID:20360939 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ARRB1 mRNA CTD PMID:20360939 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA] CTD PMID:28223344 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ATOX1 mRNA] CTD PMID:20360939 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
JBrowse link
G Axl Axl receptor tyrosine kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AXL mRNA CTD PMID:20360939 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of BAX mRNA CTD PMID:24289642 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases phosphorylation ISO caffeic acid phenethyl ester results in decreased phosphorylation of BCAR1 protein CTD PMID:10741720 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein] CTD PMID:34743973 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bgn biglycan multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of BGN mRNA CTD PMID:20360939 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of BIRC2 protein CTD PMID:15291876 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of BIRC3 protein CTD PMID:15291876 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1A mRNA CTD PMID:20360939 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1H mRNA CTD PMID:20360939 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAMK2D mRNA CTD PMID:20360939 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Capn8 calpain 8 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAPN8 mRNA] CTD PMID:20360939 NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146
JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAR3 mRNA] CTD PMID:20360939 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Car4 carbonic anhydrase 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAR4 mRNA CTD PMID:20360939 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Casp1 caspase 1 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of CASP1 protein CTD PMID:15469948 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 decreases activity
multiple interactions
increases activity
EXP
ISO
caffeic acid phenethyl ester results in decreased activity of CASP3 protein
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased activity of CASP3 protein]; caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]
caffeic acid phenethyl ester analog results in increased activity of CASP3 protein
CTD PMID:15469948 PMID:18436364 PMID:28363435 PMID:32125059 PMID:34743973 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP8 protein] CTD PMID:18436364 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased activity of CASP9 protein] CTD PMID:34743973 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP
ISO
caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; caffeic acid phenethyl ester promotes the reaction [Doxorubicin results in increased activity of CAT protein]
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]
CTD PMID:14745846 PMID:15369732 PMID:18436364 PMID:23570914 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of CCL2 mRNA] CTD PMID:16085347 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CCL5 mRNA CTD PMID:20360939 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of CCNB1 protein CTD PMID:16085347 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased expression of CCND1 mRNA; caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of CCND1 protein] CTD PMID:20420878 PMID:24289642 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP
ISO
caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein]
[Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein]
CTD PMID:15885897 PMID:16766008 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd14 CD14 molecule multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD14 mRNA
caffeic acid phenethyl ester results in increased expression of CD14 protein
caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of CD14 protein]
CTD PMID:16766008 PMID:20360939 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd151 CD151 molecule (Raph blood group) multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD151 mRNA CTD PMID:20360939 NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753
JBrowse link
G Cd86 CD86 molecule multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD86 mRNA CTD PMID:20360939 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of CDK1 protein CTD PMID:16085347 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP
ISO
caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein]
[Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein]
CTD PMID:15885897 PMID:16766008 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
caffeic acid phenethyl ester results in increased expression of CDKN1A protein
[Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of CDKN1A mRNA; caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein]; Tretinoin promotes the reaction [caffeic acid phenethyl ester results in increased expression of CDKN1A protein]
CTD PMID:15885897 PMID:16766008 PMID:24289642 PMID:26056802 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
EXP
ISO
caffeic acid phenethyl ester results in increased expression of CDKN1B protein
caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1B protein]
CTD PMID:15885897 PMID:26056802 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
EXP caffeic acid phenethyl ester results in increased expression of CDKN2A protein
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA]
CTD PMID:15885897 PMID:20360939 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CDKN2C mRNA CTD PMID:20360939 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CEACAM10 mRNA CTD PMID:20360939 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions
increases expression
ISO Tretinoin promotes the reaction [caffeic acid phenethyl ester results in increased expression of CEBPE protein] CTD PMID:16766008 NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814
JBrowse link
G Cers2 ceramide synthase 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA] CTD PMID:28223344 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314
JBrowse link
G Cers4 ceramide synthase 4 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA] CTD PMID:28223344 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828
JBrowse link
G Cgm4 carcinoembryonic antigen gene family 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CGM4 mRNA CTD PMID:20360939 NCBI chr 1:77,776,447...77,789,408
Ensembl chr 1:77,776,447...77,789,396
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CHRNA2 mRNA CTD PMID:20360939 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CHRNE mRNA CTD PMID:20360939 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
JBrowse link
G Clcn1 chloride voltage-gated channel 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CLCN1 mRNA] CTD PMID:20360939 NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984
JBrowse link
G Cldn2 claudin 2 decreases expression
multiple interactions
ISO caffeic acid phenethyl ester results in decreased expression of CLDN2 mRNA; caffeic acid phenethyl ester results in decreased expression of CLDN2 protein
Cantharidin inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein]; Chloroquine inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein]; CLDN2 protein inhibits the reaction [caffeic acid phenethyl ester results in increased susceptibility to and results in increased activity of Doxorubicin]
CTD PMID:29597147 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cldn7 claudin 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLDN7 mRNA CTD PMID:20360939 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Clic5 chloride intracellular channel 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLIC5 mRNA CTD PMID:20360939 NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427
JBrowse link
G Clock clock circadian regulator multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLOCK mRNA CTD PMID:20360939 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO caffeic acid phenethyl ester results in increased expression of COL18A1 protein CTD PMID:20433813 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Cox4i2 cytochrome c oxidase subunit 4i2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX4I2 mRNA CTD PMID:20360939 NCBI chr 3:141,228,443...141,239,337
Ensembl chr 3:141,228,443...141,239,331
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX6A2 mRNA CTD PMID:20360939 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of COX7A2 mRNA] CTD PMID:20360939 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633
Ensembl chr 8:51,301,168...51,301,633
JBrowse link
G Crmp1 collapsin response mediator protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRMP1 mRNA CTD PMID:20360939 NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177
JBrowse link
G Cs citrate synthase multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein; [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA] CTD PMID:28223344 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csk C-terminal Src kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSK mRNA CTD PMID:20360939 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSPG4 mRNA CTD PMID:20360939 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of CTNNB1 protein CTD PMID:10783313 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsk cathepsin K multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CTSK mRNA CTD PMID:20360939 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Ctsm cathepsin M multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CTSM mRNA CTD PMID:20360939 NCBI chr17:3,236,848...3,242,265
Ensembl chr17:3,236,859...3,242,265
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CXCR3 mRNA CTD PMID:20360939 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYB5A mRNA] CTD PMID:20360939 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CYBA mRNA] CTD PMID:20360939 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein] CTD PMID:15469948 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases expression
EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA
caffeic acid phenethyl ester results in decreased expression of CYP1A2 protein
CTD PMID:20360939 PMID:22291063 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2A2 mRNA CTD PMID:20360939 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression
EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2B1 mRNA
caffeic acid phenethyl ester results in decreased expression of CYP2B1 protein
CTD PMID:20360939 PMID:22291063 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of CYP2B2 protein CTD PMID:22291063 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2C13 mRNA] CTD PMID:20360939 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA
caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]
CTD PMID:18436364 PMID:20360939 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP3A18 mRNA] CTD PMID:20360939 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyth2 cytohesin 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CYTH2 mRNA CTD PMID:20360939 NCBI chr 1:96,283,182...96,291,094
Ensembl chr 1:96,284,252...96,291,092
JBrowse link
G Dbn1 drebrin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DBN1 mRNA CTD PMID:20360939 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA] CTD PMID:28223344 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Deaf1 DEAF1 transcription factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DEAF1 mRNA CTD PMID:20360939 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DEGS1 mRNA CTD PMID:20360939 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA] CTD PMID:28223344 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293
JBrowse link
G Dgkb diacylglycerol kinase, beta multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DGKB mRNA CTD PMID:20360939 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DHFR mRNA CTD PMID:20360939 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Disc1 DISC1 scaffold protein multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of DISC1 mRNA] CTD PMID:20360939 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DMRT1 mRNA CTD PMID:20360939 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333
JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH10 mRNA CTD PMID:20360939 NCBI chr12:31,823,451...31,946,857
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH5 mRNA CTD PMID:20360939 NCBI chr 2:78,937,788...79,255,551
Ensembl chr 2:78,937,800...79,254,890
JBrowse link
G Dpys dihydropyrimidinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DPYS mRNA CTD PMID:20360939 NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DUSP6 mRNA CTD PMID:20360939 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G E2f6 E2F transcription factor 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of E2F6 mRNA CTD PMID:20360939 NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ECHS1 mRNA CTD PMID:20360939 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:21926265 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ETS1 mRNA CTD PMID:20360939 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Fabp7 fatty acid binding protein 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FABP7 mRNA CTD PMID:20360939 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased expression of FAS protein] CTD PMID:18436364 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased expression of FASL protein] CTD PMID:18436364 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA] CTD PMID:28223344 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FGF7 mRNA CTD PMID:20360939 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of FGG mRNA CTD PMID:20360939 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FMO2 mRNA CTD PMID:20360939 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Foxc2 forkhead box C2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FOXC2 mRNA CTD PMID:20360939 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Foxd1 forkhead box D1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FOXD1 mRNA CTD PMID:20360939 NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978
JBrowse link
G Frmd6 FERM domain containing 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FRMD6 mRNA CTD PMID:20360939 NCBI chr 6:89,345,983...89,419,579
Ensembl chr 6:89,346,035...89,419,579
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FTL mRNA CTD PMID:20360939 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fut2 fucosyltransferase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FUT2 mRNA CTD PMID:20360939 NCBI chr 1:96,119,549...96,139,567
Ensembl chr 1:96,119,371...96,140,360
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GAS6 mRNA CTD PMID:20360939 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gc GC, vitamin D binding protein multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNA CTD PMID:20360939 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gch1 GTP cyclohydrolase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GCH1 mRNA CTD PMID:20360939 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GDNF mRNA CTD PMID:20360939 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
EXP NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of GFAP protein] CTD PMID:20836997 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfer growth factor, augmenter of liver regeneration multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GFER mRNA CTD PMID:20360939 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
JBrowse link
G Gfra4 GDNF family receptor alpha 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GFRA4 mRNA CTD PMID:20360939 NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GHR mRNA CTD PMID:20360939 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B protein] CTD PMID:15350541 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gjc2 gap junction protein, gamma 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GJC2 mRNA CTD PMID:20360939 NCBI chr10:43,962,642...43,971,358
Ensembl chr10:43,962,642...43,970,467
JBrowse link
G Gls glutaminase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GLS mRNA CTD PMID:20360939 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gnal G protein subunit alpha L multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GNAL mRNA CTD PMID:20360939 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Golga2 golgin A2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GOLGA2 mRNA CTD PMID:20360939 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
JBrowse link
G Gpr19 G protein-coupled receptor 19 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GPR19 mRNA CTD PMID:20360939 NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GRIK2 mRNA CTD PMID:20360939 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GRIK5 mRNA CTD PMID:20360939 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GSR mRNA CTD PMID:20360939 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of GSTK1 mRNA] CTD PMID:20360939 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of GSTP1 protein CTD PMID:17106925 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt2 glutathione S-transferase theta 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of GSTT2 mRNA] CTD PMID:20360939 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Gyg1 glycogenin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GYG1 mRNA CTD PMID:20360939 NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
JBrowse link
G H2ac1 H2A clustered histone 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of H2AC1 mRNA CTD PMID:20360939 NCBI chr17:41,171,324...41,171,801
Ensembl chr17:41,135,489...41,172,022
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HAMP mRNA CTD PMID:20360939 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hdgf heparin binding growth factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HDGF mRNA CTD PMID:20360939 NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of HMGCS2 mRNA] CTD PMID:20360939 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
caffeic acid phenethyl ester results in increased expression of HMOX1 protein
caffeic acid phenethyl ester analog results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester analog results in increased expression of HMOX1 protein; caffeic acid phenethyl ester results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester results in increased expression of HMOX1 protein
caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of HMOX1 protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]
CTD PMID:20226179 PMID:20950636 PMID:21472898 PMID:23942037 PMID:24508943 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HNRNPR mRNA CTD PMID:20360939 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867
JBrowse link
G Hpcal4 hippocalcin-like 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HPCAL4 mRNA CTD PMID:20360939 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPA2 mRNA CTD PMID:20360939 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA] CTD PMID:28223344 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPB1 mRNA CTD PMID:20360939 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPB2 mRNA CTD PMID:20360939 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA] CTD PMID:28223344 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA] CTD PMID:28223344 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA] CTD PMID:28223344 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IDO1 mRNA CTD PMID:20360939 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased expression of IFNG protein; caffeic acid phenethyl ester inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] CTD PMID:18953428 PMID:24289642 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igbp1 immunoglobulin binding protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IGBP1 mRNA CTD PMID:20360939 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049
JBrowse link
G Il12b interleukin 12B multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA] CTD PMID:16365417 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL18 mRNA] CTD PMID:16085347 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA] CTD PMID:16085347 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IL1B mRNA; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B protein]
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]
CTD PMID:15350541 PMID:20360939 PMID:34743973 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL2 mRNA] CTD PMID:16085347 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of IL6 protein] CTD PMID:34743973 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in decreased expression of INS1 protein CTD PMID:28223344 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Insrr insulin receptor-related receptor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of INSRR mRNA CTD PMID:20360939 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of IP6K2 mRNA] CTD PMID:20360939 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of IRS1 mRNA CTD PMID:21467634 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
ISO caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of ITGAM protein]
caffeic acid phenethyl ester results in increased expression of ITGAM protein
CTD PMID:16766008 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA] CTD PMID:28223344 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA] CTD PMID:28223344 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in increased expression of JUN mRNA] CTD PMID:16085347 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kalrn kalirin, RhoGEF kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KALRN mRNA CTD PMID:20360939 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
JBrowse link
G Kcng3 potassium voltage-gated channel modifier subfamily G member 3 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KCNG3 mRNA] CTD PMID:20360939 NCBI chr 6:11,051,311...11,099,264
Ensembl chr 6:11,051,134...11,099,264
JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNH5 mRNA CTD PMID:20360939 NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of KCNJ2 mRNA CTD PMID:20360939 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnmb2 potassium calcium-activated channel subfamily M regulatory beta subunit 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNMB2 mRNA CTD PMID:20360939 NCBI chr 2:114,670,027...114,975,374
Ensembl chr 2:114,935,976...114,975,173
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNQ2 mRNA CTD PMID:20360939 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of KCNT2 mRNA CTD PMID:26100633 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987
JBrowse link
G Kif6 kinesin family member 6 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KIF6 mRNA] CTD PMID:20360939 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Klhl17 kelch-like family member 17 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KLHL17 mRNA CTD PMID:20360939 NCBI chr 5:166,813,482...166,819,949
Ensembl chr 5:166,814,110...166,818,925
JBrowse link
G Lalba lactalbumin, alpha multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LALBA mRNA CTD PMID:20360939 NCBI chr 7:129,625,531...129,628,034
Ensembl chr 7:129,625,535...129,628,061
JBrowse link
G Lep leptin decreases expression ISO caffeic acid phenethyl ester results in decreased expression of LEP mRNA; caffeic acid phenethyl ester results in decreased expression of LEP protein CTD PMID:21467634 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Leprot leptin receptor overlapping transcript multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LEPROT mRNA CTD PMID:20360939 NCBI chr 5:116,289,843...116,301,951
Ensembl chr 5:116,289,822...116,301,988
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LGI1 mRNA CTD PMID:20360939 NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616
JBrowse link
G Lmna lamin A/C multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LMNA mRNA CTD PMID:20360939 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lrrc15 leucine rich repeat containing 15 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LRRC15 mRNA CTD PMID:20360939 NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation ISO caffeic acid phenethyl ester analog affects the phosphorylation of MAPK1 protein CTD PMID:32125059 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA CTD PMID:20360939 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation ISO caffeic acid phenethyl ester analog affects the phosphorylation of MAPK3 protein CTD PMID:32125059 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ME1 mRNA CTD PMID:20360939 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA] CTD PMID:28223344 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
EXP caffeic acid phenethyl ester results in decreased activity of MMP2 protein
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP2 protein]
CTD PMID:20836997 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MMP3 mRNA
caffeic acid phenethyl ester inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP3 protein]
CTD PMID:20360939 PMID:34791780 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
decreases activity
ISO
EXP
caffeic acid phenethyl ester results in decreased expression of MMP9 protein
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP9 protein]
CTD PMID:20433813 PMID:20836997 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in increased activity of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:15369732 PMID:20693123 PMID:21472898 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mprip myosin phosphatase Rho interacting protein multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MPRIP mRNA CTD PMID:20360939 NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118
JBrowse link
G Msx2 msh homeobox 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MSX2 mRNA CTD PMID:20360939 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Mterf1 mitochondrial transcription termination factor 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MTERF1 mRNA CTD PMID:20360939 NCBI chr 4:30,226,345...30,233,402
Ensembl chr 4:30,226,343...30,233,584
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of MTUS1 mRNA] CTD PMID:20360939 NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793
JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MUC1 mRNA CTD PMID:20360939 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Mug2 murinoglobulin 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PZP mRNA CTD PMID:20360939 NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MXI1 mRNA CTD PMID:20360939 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myo9a myosin IXA multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MYO9A mRNA CTD PMID:20360939 NCBI chr 8:60,149,234...60,352,330
Ensembl chr 8:60,149,234...60,350,514
JBrowse link
G Nat8b N-acetyltransferase 8B multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NAT8B mRNA CTD PMID:20360939 NCBI chr 4:118,359,445...118,364,351
Ensembl chr 4:118,359,443...118,363,563
JBrowse link
G Ncam1 neural cell adhesion molecule 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NCAM1 mRNA CTD PMID:20360939 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Ndufa10l1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NDUFA10L1 mRNA CTD PMID:20360939 NCBI chr 6:59,879,819...59,881,252
Ensembl chr 6:59,879,312...59,881,241
JBrowse link
G Neo1 neogenin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NEO1 mRNA CTD PMID:20360939 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in increased expression of NFE2L2 protein]
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]
CTD PMID:17204746 PMID:23570914 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfia nuclear factor I/A multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NFIA mRNA CTD PMID:20360939 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased activity of [NFKB1 protein binds to RELA protein]]
caffeic acid phenethyl ester results in decreased activity of [NFKB1 protein binds to RELA protein]
CTD PMID:11259437 PMID:16052512 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of NFKB2 protein] CTD PMID:20420878 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases phosphorylation EXP caffeic acid phenethyl ester results in decreased phosphorylation of NFKBIA protein CTD PMID:20836997 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfya nuclear transcription factor Y subunit alpha multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of NFYA mRNA] CTD PMID:20360939 NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898
JBrowse link
G Ngf nerve growth factor increases expression EXP caffeic acid phenethyl ester results in increased expression of NGF protein CTD PMID:20836997 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor increases expression
multiple interactions
affects response to substance
EXP caffeic acid phenethyl ester results in increased expression of NGFR protein
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP2 protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP9 protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of GFAP protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of RHOB protein]; NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of S100B protein]
NGFR protein affects the susceptibility to caffeic acid phenethyl ester
CTD PMID:20836997 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nog noggin multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NOG mRNA CTD PMID:20360939 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of NOS2 protein CTD PMID:15469948 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch2 notch receptor 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NOTCH2 mRNA CTD PMID:20360939 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of NOX4 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of NOX4 protein]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 protein] CTD PMID:24224404 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of NR0B2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of NR0B2 mRNA] CTD PMID:28223344 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in decreased expression of INS1 protein; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of Citric Acid; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of Fumarates; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of Ketoglutaric Acids; [[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of malic acid; [NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA] CTD PMID:28223344 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nrtn neurturin multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of NRTN mRNA CTD PMID:20360939 NCBI chr 9:1,581,860...1,587,835
Ensembl chr 9:1,581,975...1,583,102
JBrowse link
G Nup88 nucleoporin 88 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of NUP88 mRNA CTD PMID:20360939 NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
JBrowse link
G Odf1 outer dense fiber of sperm tails 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ODF1 mRNA CTD PMID:20360939 NCBI chr 7:69,377,427...69,389,662
Ensembl chr 7:69,380,116...69,389,664
JBrowse link
G Olig1 oligodendrocyte transcription factor 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of OLIG1 mRNA CTD PMID:20360939 NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein] CTD PMID:24145059 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of OPA1 mRNA CTD PMID:20360939 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pacs2 phosphofurin acidic cluster sorting protein 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA] CTD PMID:28223344 NCBI chr 6:132,096,992...132,156,702
Ensembl chr 6:132,096,901...132,154,583
JBrowse link
G Pard3 par-3 family cell polarity regulator multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PARD3 mRNA CTD PMID:20360939 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased activity of PC protein; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased activity of PC protein] CTD PMID:28223344 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PCK1 mRNA CTD PMID:20360939 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PCSK1N mRNA CTD PMID:20360939 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of PCSK2 mRNA] CTD PMID:20360939 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PCSK6 mRNA CTD PMID:20360939 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PDGFRB mRNA CTD PMID:20360939 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Per3 period circadian regulator 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PER3 mRNA CTD PMID:20360939 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PFKP mRNA CTD PMID:20360939 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Phkg2 phosphorylase kinase catalytic subunit gamma 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of PHKG2 mRNA] CTD PMID:20360939 NCBI chr 1:182,184,362...182,197,124
Ensembl chr 1:182,184,650...182,197,124
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PIAS2 mRNA CTD PMID:20360939 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] CTD PMID:18953428 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PLCG1 mRNA CTD PMID:20360939 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plekha5 pleckstrin homology domain containing A5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PLEKHA5 mRNA CTD PMID:20360939 NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA] CTD PMID:20360939 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of POLG mRNA CTD PMID:20360939 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO caffeic acid phenethyl ester results in decreased expression of PPARG mRNA CTD PMID:21467634 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PPP2R2A mRNA CTD PMID:20360939 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PPP4C mRNA CTD PMID:20360939 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659
JBrowse link
G Prep prolyl endopeptidase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PREP mRNA CTD PMID:20360939 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRKACA mRNA CTD PMID:20360939 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRKAR2A mRNA CTD PMID:20360939 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRKCE mRNA CTD PMID:20360939 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prok2 prokineticin 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of PROK2 mRNA] CTD PMID:20360939 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Prom1 prominin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PROM1 mRNA CTD PMID:20360939 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prss12 serine protease 12 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRSS12 mRNA CTD PMID:20360939 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126
JBrowse link
G Prss3 serine protease 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PRSS3 mRNA CTD PMID:20360939 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562
JBrowse link
G Psma7 proteasome 20S subunit alpha 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PSMA7 mRNA CTD PMID:20360939 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases phosphorylation ISO caffeic acid phenethyl ester results in decreased phosphorylation of PTK2 protein CTD PMID:10741720 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PTPN1 mRNA CTD PMID:20360939 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ramp1 receptor activity modifying protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RAMP1 mRNA CTD PMID:20360939 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
JBrowse link
G Rara retinoic acid receptor, alpha increases activity
increases expression
multiple interactions
ISO caffeic acid phenethyl ester results in increased activity of RARA protein
caffeic acid phenethyl ester results in increased expression of RARA mRNA; caffeic acid phenethyl ester results in increased expression of RARA protein
[Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA mRNA; [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA protein; caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased activity of RARA protein]
CTD PMID:16766008 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of RB1 protein modified form CTD PMID:15885897 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rcan1 regulator of calcineurin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of RCAN1 mRNA CTD PMID:20360939 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Paclitaxel results in increased activity of RELA protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased activity of RELA protein]; caffeic acid phenethyl ester results in decreased activity of [NFKB1 protein binds to RELA protein]
caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:11259437 PMID:15291876 PMID:16052512 PMID:26562779 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rem2 RRAD and GEM like GTPase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of REM2 mRNA CTD PMID:20360939 NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429
JBrowse link
G Ret ret proto-oncogene multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RET mRNA CTD PMID:20360939 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Retn resistin decreases expression ISO caffeic acid phenethyl ester results in decreased expression of RETN protein CTD PMID:21467634 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rfc1 replication factor C subunit 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RFC1 mRNA CTD PMID:20360939 NCBI chr14:42,966,279...43,041,372
Ensembl chr14:42,966,324...43,041,370
JBrowse link
G Rgs6 regulator of G-protein signaling 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RGS6 mRNA CTD PMID:20360939 NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753
JBrowse link
G Rhob ras homolog family member B multiple interactions
increases expression
EXP NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of RHOB protein] CTD PMID:20836997 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPE65 mRNA CTD PMID:20360939 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
JBrowse link
G Rph3a rabphilin 3A multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPH3A mRNA CTD PMID:20360939 NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592
JBrowse link
G Rpl26 ribosomal protein L26 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of RPL26 mRNA] CTD PMID:20360939 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Rps3a ribosomal protein S3a multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPS3A mRNA CTD PMID:20360939 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Mustard Compounds results in increased phosphorylation of RPS6KA2 protein]; caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of RPS6KA2 protein] CTD PMID:17204746 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
G Rps9 ribosomal protein S9 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPS9 mRNA CTD PMID:20360939 NCBI chr 1:65,511,723...65,515,076
Ensembl chr 1:65,511,723...65,515,123
JBrowse link
G RT1-A3 RT1 class I, locus A3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RT1-A3 mRNA CTD PMID:20360939 NCBI chr20:4,847,518...4,851,344 JBrowse link
G RT1-N1 RT1 class Ib, locus N1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RT1-N1 mRNA CTD PMID:20360939
G RT1-S3 RT1 class Ib, locus S3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RT1-S3 mRNA; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of RT1-S3 mRNA CTD PMID:20360939 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein] CTD PMID:28363435 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S100b S100 calcium binding protein B increases expression
multiple interactions
EXP caffeic acid phenethyl ester results in increased expression of S100B protein
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of S100B protein]
CTD PMID:20836997 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Scaper S-phase cyclin A-associated protein in the ER multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SCAPER mRNA CTD PMID:20360939 NCBI chr 8:55,932,717...56,332,222
Ensembl chr 8:55,933,306...56,332,122
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of SCD1 mRNA] CTD PMID:20360939 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of SCNN1G mRNA] CTD PMID:20360939 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
JBrowse link
G Sdc4 syndecan 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of SDC4 mRNA CTD PMID:20360939 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Sds serine dehydratase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SDS mRNA CTD PMID:20360939 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINB2 mRNA CTD PMID:20360939 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Serpinb5 serpin family B member 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINB5 mRNA CTD PMID:20360939 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpinf1 serpin family F member 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SERPINF1 mRNA CTD PMID:20360939 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sirt2 sirtuin 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SIRT2 mRNA CTD PMID:20360939 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Slc12a8 solute carrier family 12, member 8 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC12A8 mRNA CTD PMID:20360939 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834
JBrowse link
G Slc14a2 solute carrier family 14 member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC14A2 mRNA CTD PMID:20360939 NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
JBrowse link
G Slc17a8 solute carrier family 17 member 8 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC17A8 mRNA] CTD PMID:20360939 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
JBrowse link
G Slc1a1 solute carrier family 1 member 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC1A1 mRNA CTD PMID:20360939 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC1A5 mRNA CTD PMID:20360939 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC38A2 mRNA CTD PMID:20360939 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc45a1 solute carrier family 45, member 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC45A1 mRNA CTD PMID:20360939 NCBI chr 5:161,105,137...161,129,375
Ensembl chr 5:161,105,235...161,129,303
JBrowse link
G Slc4a2 solute carrier family 4 member 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC4A2 mRNA] CTD PMID:20360939 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
JBrowse link
G Slc51a solute carrier family 51 member A multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51A mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51A mRNA] CTD PMID:28223344 NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
JBrowse link
G Slc51b SLC51 subunit beta multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51B mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51B mRNA] CTD PMID:28223344 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
JBrowse link
G Slc6a9 solute carrier family 6 member 9 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SLC6A9 mRNA CTD PMID:20360939 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA] CTD PMID:28223344 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA] CTD PMID:28223344 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of SND1 mRNA CTD PMID:20360939 NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
JBrowse link
G Soat1 sterol O-acyltransferase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SOAT1 mRNA CTD PMID:20360939 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in decreased expression of SOD1 protein] CTD PMID:22692362 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sox10 SRY-box transcription factor 10 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SOX10 mRNA CTD PMID:20360939 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
JBrowse link
G Spa17 sperm autoantigenic protein 17 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SPA17 mRNA CTD PMID:20360939 NCBI chr 8:37,307,432...37,318,519
Ensembl chr 8:37,307,557...37,318,639
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SPHK1 mRNA CTD PMID:20360939 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA] CTD PMID:28223344 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]
caffeic acid phenethyl ester analog affects the expression of and affects the phosphorylation of STAT3 protein
CTD PMID:22155090 PMID:32125059 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Strn striatin multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of STRN mRNA CTD PMID:20360939 NCBI chr 6:16,335,265...16,422,159
Ensembl chr 6:16,335,358...16,417,083
JBrowse link
G Stx2 syntaxin 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of STX2 mRNA CTD PMID:20360939 NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751
JBrowse link
G Tec tec protein tyrosine kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TEC mRNA CTD PMID:20360939 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
JBrowse link
G Tg thyroglobulin multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TG mRNA CTD PMID:20360939 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of TGFB2 mRNA] CTD PMID:16085347 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgm4 transglutaminase 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TGM4 mRNA CTD PMID:20360939 NCBI chr 8:122,689,429...122,726,463
Ensembl chr 8:122,689,429...122,726,463
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TH mRNA CTD PMID:20360939 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tk1 thymidine kinase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TK1 mRNA CTD PMID:20360939 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tkt transketolase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TKT mRNA CTD PMID:20360939 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of TLR4 protein] CTD PMID:34743973 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmod2 tropomodulin 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of TMOD2 mRNA] CTD PMID:20360939 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased activity of RELA protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Vehicle Emissions results in increased expression of TNF protein]
caffeic acid phenethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased expression of TNF protein]
caffeic acid phenethyl ester results in decreased expression of TNF protein
caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of TNF protein]
CTD PMID:10757128 PMID:11259437 PMID:15291876 PMID:16085347 PMID:16271621 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of TNFRSF10A mRNA CTD PMID:24289642 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA] CTD PMID:28363435 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased expression of TNFSF11 mRNA] CTD PMID:28363435 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnnt1 troponin T1, slow skeletal type multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of TNNT1 mRNA] CTD PMID:20360939 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO
EXP
caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of TP53 protein]; caffeic acid phenethyl ester inhibits the reaction [Mustard Compounds results in increased phosphorylation of TP53 protein]; caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of TP53 protein]; caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in decreased expression of TP53 protein]
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA]
CTD PMID:17204746 PMID:20360939 PMID:22692362 PMID:26056802 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trim17 tripartite motif-containing 17 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of TRIM17 mRNA CTD PMID:20360939 NCBI chr10:43,743,111...43,750,929
Ensembl chr10:43,740,604...43,750,919
JBrowse link
G Ttn titin multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TTN mRNA CTD PMID:20360939 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Txnl1 thioredoxin-like 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TXNL1 mRNA CTD PMID:20360939 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
JBrowse link
G Tyr tyrosinase multiple interactions
affects response to substance
increases oxidation
ISO [TYR protein affects the susceptibility to caffeic acid phenethyl ester] which affects the abundance of Glutathione; [TYR protein affects the susceptibility to caffeic acid phenethyl ester] which affects the abundance of Reactive Oxygen Species; ethylenediamine inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid]; ethylenediamine inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD]; ethylenediamine inhibits the reaction [TYR protein results in increased oxidation of caffeic acid phenethyl ester]; Glutathione inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid]; Glutathione inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD]; Glutathione inhibits the reaction [TYR protein results in increased oxidation of caffeic acid phenethyl ester]; TYR protein results in increased metabolism of and results in increased susceptibility to caffeic acid phenethyl ester
[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of Ascorbic Acid; [TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD; TYR protein results in increased oxidation of caffeic acid phenethyl ester
CTD PMID:20685355 PMID:21458432 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VAMP8 mRNA CTD PMID:20360939 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:16271621 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VCPIP1 mRNA CTD PMID:20360939 NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA] CTD PMID:28223344 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VEGFA protein] CTD PMID:34791780 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vtn vitronectin multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VTN mRNA CTD PMID:20360939 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
JBrowse link
G Vwf von Willebrand factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of VWF mRNA CTD PMID:20360939 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of WRNIP1 mRNA CTD PMID:20360939 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO caffeic acid phenethyl ester results in decreased expression of XIAP protein CTD PMID:15291876 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of XRCC5 mRNA CTD PMID:20360939 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Ybx3 Y box binding protein 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of YBX3 mRNA CTD PMID:20360939 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
G Yy1 YY1 transcription factor multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of YY1 mRNA] CTD PMID:20360939 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfp180 zinc finger protein 180 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZFP180 mRNA CTD PMID:20360939 NCBI chr 1:79,652,441...79,672,737
Ensembl chr 1:79,652,441...79,672,733
JBrowse link
G Zfp37 zinc finger protein 37 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP37 mRNA] CTD PMID:20360939 NCBI chr 5:75,598,732...75,638,896
Ensembl chr 5:75,598,732...75,638,942
JBrowse link
G Zfp384 zinc finger protein 384 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZFP384 mRNA CTD PMID:20360939 NCBI chr 4:157,810,263...157,840,052
Ensembl chr 4:157,810,352...157,839,766
JBrowse link
G Zfp394 zinc finger protein 394 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZNF394 mRNA CTD PMID:20360939 NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246
JBrowse link
G Zhx1 zinc fingers and homeoboxes 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ZHX1 mRNA CTD PMID:20360939 NCBI chr 7:89,582,363...89,611,337
Ensembl chr 7:89,582,243...89,611,264
JBrowse link
rosmarinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ACACA mRNA] CTD PMID:33476690 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
multiple interactions
EXP Rosmarinic Acid results in decreased expression of ACTA2 protein
Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
CTD PMID:28789951 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression
multiple interactions
ISO Rosmarinic Acid results in decreased expression of ADAM17 protein
[Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [IL1B protein affects the localization of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [IL1B protein results in increased cleavage of and results in increased secretion of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [TNF protein affects the localization of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [TNF protein results in increased cleavage of and results in increased secretion of PROCR protein]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]
CTD PMID:23774263 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ADIPOQ mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ADIPOQ protein] CTD PMID:33476690 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO Rosmarinic Acid inhibits the reaction [Cadmium affects the localization of AIFM1 protein]; Rosmarinic Acid inhibits the reaction [Cisplatin affects the localization of AIFM1 protein] CTD PMID:21526214 PMID:23548128 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Rosmarinic Acid inhibits the reaction [Cisplatin results in increased expression of BAX protein] CTD PMID:21526214 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Rosmarinic Acid inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein] CTD PMID:21526214 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Rosmarinic Acid inhibits the reaction [Cisplatin results in increased activity of CASP1 protein] CTD PMID:21526214 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO
EXP
Rosmarinic Acid inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Rosmarinic Acid inhibits the reaction [Cadmium results in increased activity of CASP3 protein]; Rosmarinic Acid inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]
Rosmarinic Acid results in increased expression of CASP3 mRNA
Rosmarinic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]
CTD PMID:20966113 PMID:21526214 PMID:23548128 PMID:28815802 PMID:36863647 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases expression
increases activity
ISO Rosmarinic Acid results in increased expression of CASP8 mRNA
Rosmarinic Acid results in increased activity of CASP8 protein
CTD PMID:36863647 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Rosmarinic Acid inhibits the reaction [Cisplatin results in increased activity of CASP9 protein] CTD PMID:21526214 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases activity
multiple interactions
increases expression
ISO Rosmarinic Acid results in increased activity of CAT protein
Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of CAT protein]; Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT mRNA]
Rosmarinic Acid results in increased expression of CAT mRNA
CTD PMID:31610155 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
decreases expression
EXP Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein]
Rosmarinic Acid results in decreased expression of CCN2 mRNA
CTD PMID:28789951 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of CCND1 protein] CTD PMID:28789951 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd68 Cd68 molecule decreases expression EXP Rosmarinic Acid results in decreased expression of CD68 protein CTD PMID:28789951 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of CEBPA mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of CEBPA protein] CTD PMID:33476690 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions
EXP
ISO
Rosmarinic Acid results in decreased expression of COL1A1 mRNA
Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD PMID:27235791 PMID:28789951 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
decreases expression
EXP Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]
Rosmarinic Acid results in decreased expression of COL3A1 mRNA
CTD PMID:28789951 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Crp C-reactive protein affects expression
multiple interactions
EXP Rosmarinic Acid affects the expression of CRP protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of CRP protein]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of CRP protein]
CTD PMID:28744220 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
multiple interactions
ISO Rosmarinic Acid results in decreased expression of CXCL1 mRNA
Rosmarinic Acid inhibits the reaction [Particulate Matter results in increased expression of CXCL1 protein]; Rosmarinic Acid inhibits the reaction [Vehicle Emissions results in increased expression of CXCL1 protein]
CTD PMID:12684091 PMID:26804033 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Des desmin multiple interactions EXP Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of DES protein] CTD PMID:28789951 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO Rosmarinic Acid results in decreased expression of DNMT1 protein CTD PMID:21078381 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of FABP4 mRNA] CTD PMID:33476690 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of FASN mRNA] CTD PMID:33476690 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Rosmarinic Acid results in decreased expression of FN1 mRNA CTD PMID:26804033 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Rosmarinic Acid results in decreased expression of FOS protein CTD PMID:28789951 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gpt glutamic--pyruvic transaminase decreases activity EXP Rosmarinic Acid results in decreased activity of GPT protein CTD PMID:25455894 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
ISO Rosmarinic Acid results in increased expression of GPX1 mRNA
Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GPX1 mRNA]
CTD PMID:31610155 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions
increases expression
ISO Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA]
Rosmarinic Acid results in increased expression of GSTO1 mRNA
CTD PMID:31610155 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression EXP Rosmarinic Acid results in decreased expression of HMGB1 protein CTD PMID:28789951 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Rosmarinic Acid results in increased expression of HMOX1 mRNA
Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 mRNA]
CTD PMID:31610155 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of IL10 mRNA] CTD PMID:33476690 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of IL17A mRNA] CTD PMID:33476690 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
[Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [IL1B protein affects the localization of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [IL1B protein results in increased cleavage of and results in increased secretion of PROCR protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of IL1B mRNA]
Rosmarinic Acid results in decreased expression of IL1B mRNA; Rosmarinic Acid results in decreased expression of IL1B protein
Rosmarinic Acid inhibits the reaction [Cadmium results in increased expression of IL1B protein]; Rosmarinic Acid inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]; Rosmarinic Acid inhibits the reaction [Vehicle Emissions results in increased expression of IL1B protein]
CTD PMID:12684091 PMID:23548128 PMID:23774263 PMID:25455894 PMID:28789951 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression
affects expression
ISO
EXP
Rosmarinic Acid inhibits the reaction [Cadmium results in increased expression of IL6 protein]
Rosmarinic Acid results in decreased expression of IL6 protein
Rosmarinic Acid results in decreased expression of IL6 mRNA
Rosmarinic Acid results in increased expression of IL6 mRNA
Rosmarinic Acid affects the expression of IL6 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of IL6 protein]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of IL6 protein]
CTD PMID:23548128 PMID:26804033 PMID:28744220 PMID:28789951 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of NFE2L2 mRNA; [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of TGFB1 mRNA; [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of NFKBIA mRNA; Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of CEBPA mRNA]; Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of IL10 mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of IL17A mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ACACA mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ADIPOQ mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ADIPOQ protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of CEBPA protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of FABP4 mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of FASN mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of IL1B mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARA mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARD mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARG protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of UCP1 mRNA] CTD PMID:33476690 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases phosphorylation EXP Rosmarinic Acid results in decreased phosphorylation of JUN protein CTD PMID:28789951 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnu1 potassium calcium-activated channel subfamily U member 1 decreases activity ISO Rosmarinic Acid results in decreased activity of KCNU1 protein CTD PMID:30009954 NCBI chr16:66,141,696...66,229,493
Ensembl chr16:66,141,976...66,229,465
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
ISO Rosmarinic Acid results in decreased expression of KEAP1 protein
Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein]
CTD PMID:31610155 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO Rosmarinic Acid results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity ISO Rosmarinic Acid results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases phosphorylation EXP Rosmarinic Acid results in decreased phosphorylation of MAP3K7 protein CTD PMID:28789951 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP Rosmarinic Acid results in decreased phosphorylation of MAPK1 protein CTD PMID:28789951 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP Rosmarinic Acid results in decreased phosphorylation of MAPK3 protein CTD PMID:28789951 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases phosphorylation EXP Rosmarinic Acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28789951 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases phosphorylation EXP Rosmarinic Acid results in decreased phosphorylation of MAPK9 protein CTD PMID:28789951 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP Rosmarinic Acid results in decreased expression of MMP2 mRNA; Rosmarinic Acid results in decreased expression of MMP2 protein CTD PMID:28789951 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP Rosmarinic Acid results in decreased expression of MMP9 mRNA; Rosmarinic Acid results in decreased expression of MMP9 protein CTD PMID:28789951 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase decreases expression EXP Rosmarinic Acid results in decreased expression of MPO protein CTD PMID:28789951 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression EXP Rosmarinic Acid results in decreased expression of MYD88 protein CTD PMID:28789951 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
ISO Rosmarinic Acid results in increased expression of NFE2L2 mRNA; Rosmarinic Acid results in increased expression of NFE2L2 protein
[lead acetate results in increased abundance of Lead] inhibits the reaction [Rosmarinic Acid results in increased expression of NFE2L2 protein]; [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of NFE2L2 mRNA; Rosmarinic Acid affects the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA]
CTD PMID:31610155 PMID:33476690 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of NFKBIA mRNA
Rosmarinic Acid inhibits the reaction [Cisplatin results in increased degradation of NFKBIA protein]
CTD PMID:21526214 PMID:33476690 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 decreases expression ISO Rosmarinic Acid results in decreased expression of NLRP3 mRNA CTD PMID:36863647 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP Rosmarinic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]
Rosmarinic Acid results in decreased expression of NOS2 protein
CTD PMID:25455894 PMID:28815802 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 decreases expression EXP Rosmarinic Acid results in decreased expression of NOS3 protein CTD PMID:25455894 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of NQO1 mRNA]
Rosmarinic Acid results in increased expression of NQO1 mRNA
CTD PMID:31610155 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression EXP Rosmarinic Acid results in increased expression of OGG1 mRNA CTD PMID:18996367 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO Rosmarinic Acid results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARA mRNA] CTD PMID:33476690 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARD mRNA] CTD PMID:33476690 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
multiple interactions
EXP
ISO
Rosmarinic Acid affects the expression of PPARG mRNA; Rosmarinic Acid affects the expression of PPARG protein
Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARG protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of PPARG mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of PPARG protein]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of PPARG mRNA]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of PPARG protein]
CTD PMID:28744220 PMID:33476690 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA] CTD PMID:33476690 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Procr protein C receptor affects localization
multiple interactions
ISO Rosmarinic Acid affects the localization of PROCR protein
Rosmarinic Acid results in decreased cleavage of and results in decreased secretion of PROCR protein
[Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [IL1B protein affects the localization of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [IL1B protein results in increased cleavage of and results in increased secretion of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [TNF protein affects the localization of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [TNF protein results in increased cleavage of and results in increased secretion of PROCR protein]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PROCR protein]; Rosmarinic Acid results in decreased cleavage of and results in decreased secretion of PROCR protein
CTD PMID:23774263 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects expression
decreases phosphorylation
affects localization
EXP
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of RELA mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of RELA protein]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of RELA mRNA]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of RELA protein]
Rosmarinic Acid inhibits the reaction [Cisplatin affects the localization of RELA protein]
Rosmarinic Acid affects the expression of RELA mRNA; Rosmarinic Acid affects the expression of RELA protein
Rosmarinic Acid results in decreased phosphorylation of RELA protein
Rosmarinic Acid affects the localization of RELA protein
CTD PMID:21526214 PMID:25455894 PMID:28744220 PMID:28789951 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Rosmarinic Acid results in decreased expression of SERPINE1 mRNA CTD PMID:26804033 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SOD1 mRNA]
Rosmarinic Acid results in increased expression of SOD1 mRNA
CTD PMID:31610155 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SOD2 mRNA]
Rosmarinic Acid results in increased expression of SOD2 mRNA
CTD PMID:31610155 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA] CTD PMID:33476690 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tf transferrin multiple interactions ISO [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of NFE2L2 mRNA; [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of TGFB1 mRNA; [Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of NFKBIA mRNA; Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of CEBPA mRNA]; Rosmarinic Acid affects the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARGC1A mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of IL10 mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of IL17A mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ACACA mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ADIPOQ mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of ADIPOQ protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of CEBPA protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of FABP4 mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of FASN mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of IL1B mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARA mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARD mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of PPARG protein]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of SREBF1 mRNA]; Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of UCP1 mRNA] CTD PMID:33476690 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
EXP
ISO
Rosmarinic Acid results in decreased expression of TGFB1 protein
[Rosmarinic Acid co-treated with Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in decreased expression of TGFB1 mRNA
Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein]; Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of CCND1 protein]; Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]; Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of DES protein]; Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]
CTD PMID:28789951 PMID:33476690 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression EXP Rosmarinic Acid results in decreased expression of TLR4 protein CTD PMID:28789951 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor affects expression
decreases expression
multiple interactions
EXP
ISO
Rosmarinic Acid affects the expression of TNF protein
Rosmarinic Acid results in decreased expression of TNF mRNA; Rosmarinic Acid results in decreased expression of TNF protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Rosmarinic Acid affects the expression of TNF protein]; Rosmarinic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; T 0070907 inhibits the reaction [Rosmarinic Acid affects the expression of TNF protein]
[Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [TNF protein affects the localization of PROCR protein]; [Rosmarinic Acid results in decreased expression of ADAM17 protein] inhibits the reaction [TNF protein results in increased cleavage of and results in increased secretion of PROCR protein]
CTD PMID:23774263 PMID:25455894 PMID:28744220 PMID:28789951 PMID:28815802 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions ISO Rosmarinic Acid inhibits the reaction [[Rosiglitazone co-treated with TF protein co-treated with INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Hydrocortisone co-treated with Triiodothyronine] results in increased expression of UCP1 mRNA] CTD PMID:33476690 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Vim vimentin multiple interactions EXP Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:28789951 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
trans-caffeic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO caffeic acid results in increased phosphorylation of and results in decreased activity of ACACA protein CTD PMID:28576465 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
EXP caffeic acid inhibits the reaction [Caffeine results in decreased activity of ACHE protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of ACHE protein] CTD PMID:28465162 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of ACLY protein CTD PMID:28576465 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases activity
multiple interactions
ISO caffeic acid results in decreased activity of ALOX15 protein
[caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]; [caffeic acid results in decreased activity of ALOX15 protein] which results in decreased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [caffeic acid results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; caffeic acid inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of ALOX15 protein]
CTD PMID:10904086 PMID:11406566 PMID:15574791 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO
EXP
caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 protein]
caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 protein]; caffeic acid inhibits the reaction [Hydrogen Peroxide affects the localization of ALOX5 protein]
CTD PMID:18482095 PMID:18951527 PMID:27368151 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein modified form]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein] CTD PMID:18482095 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arg1 arginase 1 decreases activity ISO caffeic acid results in decreased activity of ARG1 protein CTD PMID:27378625 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA] CTD PMID:19442820 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
[caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of CASP3 protein]
CTD PMID:15574791 PMID:29968957 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions
increases activity
ISO
EXP
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
caffeic acid results in increased activity of CAT protein
caffeic acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Nickel results in decreased activity of CAT protein]
CTD PMID:18405891 PMID:21640567 PMID:22036979 PMID:27378625 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL2 mRNA; caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:16806235 PMID:31306686 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL3 mRNA CTD PMID:16806235 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL4 mRNA CTD PMID:16806235 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR1 mRNA CTD PMID:16806235 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR2 mRNA CTD PMID:16806235 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR4 mRNA CTD PMID:16806235 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD4 mRNA CTD PMID:16806235 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD68 mRNA CTD PMID:16806235 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA CTD PMID:19442820 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] CTD PMID:19442820 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO caffeic acid inhibits the reaction [aluminum chloride results in decreased expression of CHAT protein] CTD PMID:18482095 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of caffeic acid CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:25404496 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA] CTD PMID:19442820 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Ctsb cathepsin B multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein] CTD PMID:20391626 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:20391626 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA] CTD PMID:19442820 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dap death-associated protein multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA] CTD PMID:19442820 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA] CTD PMID:19442820 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA] CTD PMID:19442820 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA CTD PMID:16806235 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO caffeic acid affects the reaction [Acetaminophen results in increased expression of and affects the localization of EGR1 protein]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of EGR1 mRNA] CTD PMID:27720869 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elmo2 engulfment and cell motility 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA] CTD PMID:19442820 NCBI chr 3:154,023,661...154,061,259
Ensembl chr 3:154,023,661...154,061,185
JBrowse link
G Erf Ets2 repressor factor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA] CTD PMID:19442820 NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of F3 protein] CTD PMID:27720869 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
ISO caffeic acid results in decreased expression of FASN mRNA
[Metformin co-treated with caffeic acid] results in decreased expression of FASN protein
CTD PMID:21870829 PMID:28576465 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA] CTD PMID:19442820 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA] CTD PMID:19442820 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO caffeic acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A mRNA]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A protein] CTD PMID:27720869 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein] CTD PMID:20391626 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gls glutaminase increases expression ISO caffeic acid results in increased expression of GLS protein CTD PMID:28576465 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15212457 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein]
caffeic acid inhibits the reaction [Acetaminophen results in increased activity of GPT protein]
CTD PMID:15212457 PMID:27720869 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]
CTD PMID:19442820 PMID:21640567 PMID:22036979 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity EXP caffeic acid results in decreased activity of GSTM1 protein CTD PMID:8340025 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases activity EXP caffeic acid results in decreased activity of GSTM2 protein CTD PMID:8340025 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity EXP caffeic acid results in decreased activity of GSTP1 protein CTD PMID:8340025 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:20391626 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions EXP caffeic acid inhibits the reaction [Cisplatin results in decreased activity of H6PD protein] CTD PMID:21640567 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of HAVCR2 mRNA CTD PMID:16806235 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of HES1 mRNA] CTD PMID:29968957 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO caffeic acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO caffeic acid results in decreased expression of HMGCR mRNA CTD PMID:21870829 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA] CTD PMID:19442820 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA] CTD PMID:19442820 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of IFNG protein
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of IFNG protein]
CTD PMID:27378625 PMID:29968957 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 decreases expression ISO caffeic acid results in decreased expression of IL10 protein CTD PMID:27378625 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL1B protein]
CTD PMID:27368151 PMID:27720869 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO caffeic acid results in increased expression of IL2 protein CTD PMID:27378625 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21r interleukin 21 receptor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA] CTD PMID:19442820 NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522
JBrowse link
G Il4 interleukin 4 decreases expression ISO caffeic acid results in decreased expression of IL4 protein CTD PMID:27378625 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of IL6 mRNA
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL6 protein]
CTD PMID:21870829 PMID:27368151 PMID:27720869 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kif15 kinesin family member 15 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of KIF15 mRNA CTD PMID:19442820 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif20b kinesin family member 20B multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA] CTD PMID:19442820 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO caffeic acid inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA] CTD PMID:19442820 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:21472895 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:21472895 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO caffeic acid results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity ISO caffeic acid results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in decreased expression of MAP2K5 mRNA CTD PMID:19442820 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK1 protein] CTD PMID:27720869 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK3 protein] CTD PMID:27720869 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MFN1 mRNA] CTD PMID:19442820 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases activity EXP caffeic acid results in increased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
ISO
EXP
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]
caffeic acid inhibits the reaction [Ethanol results in increased activity of MPO protein]; NG-Nitroarginine Methyl Ester inhibits the reaction [caffeic acid inhibits the reaction [Ethanol results in increased activity of MPO protein]]
caffeic acid results in decreased activity of MPO protein
CTD PMID:22036979 PMID:24060682 PMID:33301711 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRPL45 mRNA] CTD PMID:19442820 NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474
JBrowse link
G Mrrf mitochondrial ribosome recycling factor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA] CTD PMID:19442820 NCBI chr 3:19,487,124...19,543,911
Ensembl chr 3:19,487,182...19,543,908
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [caffeic acid co-treated with Zymosan] results in increased expression of COX2 protein; caffeic acid inhibits the reaction [Zymosan results in increased expression of COX2 protein] CTD PMID:30481570 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Ndp norrin cystine knot growth factor NDP increases expression ISO caffeic acid results in increased expression of NDP mRNA CTD PMID:19442820 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOS2 protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:29968957 PMID:31306686 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO caffeic acid results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA] CTD PMID:29968957 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions
decreases activity
EXP caffeic acid inhibits the reaction [Caffeine results in decreased activity of NT5E protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of NT5E protein] CTD PMID:28465162 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Pdcd10 programmed cell death 10 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PDCD10 mRNA] CTD PMID:19442820 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO caffeic acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO caffeic acid results in increased expression of PIK3R1 mRNA CTD PMID:21870829 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of PLK1 mRNA CTD PMID:19442820 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of PLK4 mRNA] CTD PMID:19442820 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO caffeic acid results in increased expression of PPARG mRNA CTD PMID:21870829 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PRDX5 mRNA] CTD PMID:19442820 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTGS2 mRNA]
CTD PMID:19442820 PMID:22036979 PMID:31306686 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTX3 mRNA] CTD PMID:19442820 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of RELA protein] CTD PMID:29968957 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of SCD1 protein CTD PMID:28576465 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein] CTD PMID:27720869 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of SFXN4 mRNA] CTD PMID:19442820 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO caffeic acid results in increased expression of SLC2A2 mRNA CTD PMID:33493636 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO caffeic acid results in increased expression of SLC2A4 mRNA CTD PMID:21870829 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO caffeic acid results in increased expression of SLC5A1 mRNA CTD PMID:33493636 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
JBrowse link
G Snca synuclein alpha multiple interactions ISO caffeic acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stk32a serine/threonine kinase 32A multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in decreased expression of STK32A mRNA CTD PMID:19442820 NCBI chr18:35,258,865...35,374,985
Ensembl chr18:35,259,052...35,369,451
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of caffeic acid CTD PMID:17433394 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases sulfation ISO SULT1C2 protein results in increased sulfation of caffeic acid CTD PMID:17433394 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Valproic Acid results in increased expression of TNF protein]
caffeic acid results in increased expression of TNF mRNA
CTD PMID:21870829 PMID:22036979 PMID:27368151 PMID:29968957 PMID:31306686 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 affects expression
multiple interactions
ISO caffeic acid affects the expression of TP53 protein
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA]
CTD PMID:11522280 PMID:19442820 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tyr tyrosinase increases oxidation
multiple interactions
ISO TYR protein results in increased oxidation of caffeic acid
[TYR protein results in increased oxidation of caffeic acid] which results in decreased abundance of Glutathione
CTD PMID:20685355 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of UBE2C mRNA] CTD PMID:19442820 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO caffeic acid results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation
decreases activity
ISO UGT1A3 protein results in increased glucuronidation of caffeic acid
caffeic acid results in decreased activity of UGT1A3 protein
CTD PMID:15117964 PMID:35868516 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO caffeic acid results in decreased activity of UGT1A6 protein CTD PMID:35868516 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO caffeic acid results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases activity ISO caffeic acid results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO caffeic acid results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Vegfa vascular endothelial growth factor A decreases secretion ISO caffeic acid results in decreased secretion of VEGFA protein CTD PMID:27378625 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:22036979 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      chemical role 19512
        antioxidant 16062
          caffeic acid 596
            alkyl caffeate ester + 366
            caffeoyl-CoA + 0
            cis-caffeic acid + 119
            trans-caffeic acid + 294
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        monocarboxylic acid 17984
                                          alpha,beta-unsaturated monocarboxylic acid 13252
                                            cinnamic acids 2506
                                              hydroxycinnamic acid 1361
                                                caffeic acid 596
                                                  alkyl caffeate ester + 366
                                                  caffeoyl-CoA + 0
                                                  cis-caffeic acid + 119
                                                  trans-caffeic acid + 294
paths to the root