Igbp1 (immunoglobulin binding protein 1) - Rat Genome Database

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Gene: Igbp1 (immunoglobulin binding protein 1) Rattus norvegicus
Analyze
Symbol: Igbp1
Name: immunoglobulin binding protein 1
RGD ID: 62011
Description: Enables protein phosphatase 2A binding activity. Predicted to be involved in several processes, including negative regulation of stress-activated MAPK cascade; regulation of transcription by RNA polymerase II; and response to interleukin-1. Predicted to act upstream of or within negative regulation of apoptotic signaling pathway. Predicted to be located in cytoplasm and microtubule. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to several human genes including IGBP1 (immunoglobulin binding protein 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha4 phosphoprotein; CD79a-binding protein 1; immunoglobulin (CD79A) binding protein 1; immunoglobulin-binding protein 1; protein phosphatase 2/4/6 regulatory subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X69,622,925 - 69,645,167 (+)NCBIGRCr8
mRatBN7.2X65,582,832 - 65,605,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX65,582,821 - 65,606,049 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX67,066,253 - 67,088,494 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X70,566,639 - 70,588,880 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X68,127,540 - 68,149,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X70,322,764 - 70,345,005 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX70,322,755 - 70,345,005 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X71,194,717 - 71,216,957 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,490,498 - 88,507,054 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X88,566,669 - 88,580,484 (+)NCBI
CeleraX65,942,243 - 65,964,485 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Igbp1Ratautistic disorder  ISOIGBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Igbp1Ratautosomal hemophilia A  ISOIGBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA AClinVarPMID:31690835
Igbp1Ratcorpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome  ISOIGBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:28492532
Igbp1Ratfactor VIII deficiency  ISOIGBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Factor 8 deficiency and congenitalClinVarPMID:31690835
Igbp1Ratsyndromic X-linked intellectual disability Lubs type  ISOIGBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Igbp1RatBreast Neoplasms  ISOIGBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21339737
Igbp1Ratcorpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome  ISOIGBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Igbp1Rathepatocellular carcinoma  ISOIGBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21339737
Igbp1RatLung Neoplasms  ISOIGBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21339737
Igbp1RatNeoplastic Cell Transformation  ISOIGBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21339737
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Igbp1Ratcorpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome  ISOIGBP1 (Homo sapiens)7240710 OMIM 

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Object Symbol
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Term
Qualifier
Evidence
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Reference
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Source
Original Reference(s)
Igbp1Rat(+)-catechin multiple interactionsISOIGBP1 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of IGBP1 mRNACTDPMID:24763279
Igbp1Rat1,2-dimethylhydrazine affects expressionISOIgbp1 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of IGBP1 mRNACTDPMID:22206623
Igbp1Rat1-chloro-2,4-dinitrobenzene affects bindingISOIGBP1 (Homo sapiens)6480464Dinitrochlorobenzene binds to IGBP1 proteinCTDPMID:32991956
Igbp1Rat17beta-estradiol affects expressionISOIGBP1 (Homo sapiens)6480464Estradiol affects the expression of IGBP1 mRNACTDPMID:22574217
Igbp1Rat17beta-estradiol decreases expressionISOIGBP1 (Homo sapiens)6480464Estradiol results in decreased expression of IGBP1 mRNACTDPMID:31614463
Igbp1Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in decreased expression of IGBP1 mRNACTDPMID:26496021
Igbp1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOIgbp1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of IGBP1 mRNACTDPMID:19465110
Igbp1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOIGBP1 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of IGBP1 mRNACTDPMID:22574217
Igbp1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOIgbp1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of IGBP1 mRNACTDPMID:21570461
Igbp1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of IGBP1 mRNACTDPMID:21215274
Igbp1Rat4,4'-sulfonyldiphenol increases expressionISOIgbp1 (Mus musculus)6480464bisphenol S results in increased expression of IGBP1 mRNACTDPMID:39298647
Igbp1Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of IGBP1 mRNACTDPMID:31881176
Igbp1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of IGBP1 mRNACTDPMID:16483693
Igbp1Rataristolochic acid A increases expressionISOIGBP1 (Homo sapiens)6480464aristolochic acid I results in increased expression of IGBP1 mRNACTDPMID:33212167
Igbp1RatAroclor 1254 decreases expressionISOIgbp1 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in decreased expression of IGBP1 mRNACTDPMID:23650126
Igbp1Ratarsenite(3-) increases expressionISOIgbp1 (Mus musculus)6480464arsenite results in increased expression of IGBP1 proteinCTDPMID:37955338
Igbp1Ratarsenite(3-) multiple interactionsISOIGBP1 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to IGBP1 mRNA]CTDPMID:32406909
Igbp1Ratbenzo[a]pyrene affects methylationISOIGBP1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of IGBP1 5' UTR and Benzo(a)pyrene affects the methylation of IGBP1 promoterCTDPMID:27901495
Igbp1Ratbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in decreased expression of IGBP1 mRNACTDPMID:26496021
Igbp1Ratbisphenol A decreases expressionISOIGBP1 (Homo sapiens)6480464bisphenol A results in decreased expression of IGBP1 proteinCTDPMID:34186270

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Biological Process
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Object Symbol
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Qualifier
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Reference
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Source
Original Reference(s)
Igbp1RatB cell activation involved_inIEAUniProtKB-KW:KW-00751600115GO_REF:0000043UniProtGO_REF:0000043
Igbp1Ratintracellular signal transduction involved_inISOIGBP1 (Homo sapiens)1624291 PMID:17438131RGDPMID:17438131
Igbp1Ratnegative regulation of apoptotic signaling pathway acts_upstream_of_or_withinISOIgbp1 (Mus musculus)1624291MGI:2448686 more ...RGDPMID:15499020
Igbp1Ratnegative regulation of apoptotic signaling pathway acts_upstream_of_or_withinIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratnegative regulation of stress-activated MAPK cascade involved_inISOIGBP1 (Homo sapiens)1624291 PMID:17438131RGDPMID:17438131
Igbp1Ratnegative regulation of transcription by RNA polymerase II involved_inISOIGBP1 (Homo sapiens)1624291 PMID:17438131RGDPMID:17438131
Igbp1Ratpositive regulation of dephosphorylation involved_inISOIgbp1 (Mus musculus)1624291 PMID:15499020RGDPMID:15499020
Igbp1Ratpositive regulation of dephosphorylation involved_inIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratpositive regulation of transcription by RNA polymerase II involved_inISOIgbp1 (Mus musculus)1624291 PMID:15499020RGDPMID:15499020
Igbp1Ratpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratregulation of dephosphorylation involved_inIBAMGI:1346500 and PANTHER:PTN0001011301600115GO_REF:0000033GO_CentralGO_REF:0000033
Igbp1Ratregulation of microtubule-based movement involved_inISOIGBP1 (Homo sapiens)1624291 PMID:18949047RGDPMID:18949047
Igbp1Ratregulation of signal transduction involved_inIEAInterPro:IPR0073041600115GO_REF:0000002InterProGO_REF:0000002
Igbp1Ratresponse to interleukin-1 involved_inISOIGBP1 (Homo sapiens)1624291 PMID:17438131RGDPMID:17438131
Igbp1Ratresponse to tumor necrosis factor involved_inISOIGBP1 (Homo sapiens)1624291 PMID:17438131RGDPMID:17438131
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Cellular Component

  
Object Symbol
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Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Igbp1Ratcytoplasm located_inISOIgbp1 (Mus musculus)1624291 PMID:11806752RGDPMID:11806752
Igbp1Ratcytoplasm located_inIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Igbp1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Igbp1Ratcytosol is_active_inIBAPANTHER:PTN000101130 and SGD:S0000046301600115GO_REF:0000033GO_CentralGO_REF:0000033
Igbp1Ratmicrotubule located_inISOIgbp1 (Mus musculus)1624291UniProtKB:O15344 more ...RGDPMID:11806752
Igbp1Ratmicrotubule located_inIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function
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Object Symbol
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Term
Qualifier
Evidence
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Reference
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Source
Original Reference(s)
Igbp1Ratenzyme binding enablesISOIgbp1 (Mus musculus)1624291UniProtKB:O15344 more ...RGDPMID:11806752
Igbp1Ratenzyme binding enablesIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratmitogen-activated protein kinase kinase binding enablesISOIgbp1 (Mus musculus)1624291UniProtKB:O09110 and PMID:17438131RGDPMID:17438131
Igbp1Ratmitogen-activated protein kinase kinase binding enablesIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratprotein binding enablesISOIGBP1 (Homo sapiens)1624291UniProtKB:O00743 more ...RGDPMID:16085932 more ...
Igbp1Ratprotein binding enablesISOIgbp1 (Mus musculus)1624291UniProtKB:O15344 more ...RGDPMID:12963337 more ...
Igbp1Ratprotein domain specific binding enablesISOIgbp1 (Mus musculus)1624291 PMID:11806752RGDPMID:11806752
Igbp1Ratprotein domain specific binding enablesIEAUniProtKB:Q61249 and ensembl:ENSMUSP000000335701600115GO_REF:0000107EnsemblGO_REF:0000107
Igbp1Ratprotein phosphatase 2A binding  IPIPpp2ca (Rattus norvegicus)8693401 RGD 
Igbp1Ratprotein phosphatase 2A binding enablesIBAPANTHER:PTN000101130 and Igbp1 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Igbp1Ratprotein phosphatase regulator activity enablesISOIGBP1 (Homo sapiens)1624291 PMID:9647778RGDPMID:9647778
Igbp1Ratprotein-containing complex binding  IPIPpp2ca (Rattus norvegicus) and Cpd (Rattus norvegicus)8693401 RGD 
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells. O'Malley PG, etal., Biochem J. 2005 Sep 15;390(Pt 3):665-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11. Differential expression of elongation factor-2, alpha4 phosphoprotein and Cdc5-like protein in prolactin-dependent/independent rat lymphoid cells. Too CK Mol Cell Endocrinol 1997 Aug 8;131(2):221-32.
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PMID:9647778   PMID:9792806   PMID:11806752   PMID:15489334   PMID:15499020   PMID:17438131   PMID:18949047   PMID:20544796   PMID:28526910   PMID:33737606  



Igbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X69,622,925 - 69,645,167 (+)NCBIGRCr8
mRatBN7.2X65,582,832 - 65,605,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX65,582,821 - 65,606,049 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX67,066,253 - 67,088,494 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X70,566,639 - 70,588,880 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X68,127,540 - 68,149,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X70,322,764 - 70,345,005 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX70,322,755 - 70,345,005 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X71,194,717 - 71,216,957 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,490,498 - 88,507,054 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X88,566,669 - 88,580,484 (+)NCBI
CeleraX65,942,243 - 65,964,485 (+)NCBICelera
Cytogenetic MapXq22NCBI
IGBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X70,133,447 - 70,166,324 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX70,133,447 - 70,166,324 (+)EnsemblGRCh38hg38GRCh38
GRCh37X69,353,297 - 69,386,174 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,270,043 - 69,302,899 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X69,136,338 - 69,169,192NCBI
CeleraX69,706,683 - 69,739,540 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX63,174,076 - 63,207,564 (+)NCBIHuRef
CHM1_1X69,246,939 - 69,279,788 (+)NCBICHM1_1
T2T-CHM13v2.0X68,566,802 - 68,599,681 (+)NCBIT2T-CHM13v2.0
Igbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X99,537,897 - 99,559,731 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX99,537,897 - 99,559,731 (+)EnsemblGRCm39 Ensembl
GRCm38X100,494,291 - 100,516,125 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX100,494,291 - 100,516,125 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X97,689,630 - 97,711,464 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X96,697,064 - 96,718,720 (+)NCBIMGSCv36mm8
CeleraX87,420,356 - 87,442,287 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.72NCBI
Igbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554759,671,162 - 9,694,926 (+)NCBIChiLan1.0ChiLan1.0
IGBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X69,810,161 - 69,843,192 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X69,813,728 - 69,846,794 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X59,401,426 - 59,434,363 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X69,460,736 - 69,493,616 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX69,460,734 - 69,493,616 (+)Ensemblpanpan1.1panPan2
IGBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X54,558,515 - 54,612,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX54,547,446 - 54,613,171 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX45,384,171 - 45,437,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X55,524,457 - 55,577,975 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX55,513,867 - 55,579,130 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X53,493,501 - 53,547,031 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X54,824,297 - 54,877,823 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X54,751,460 - 54,804,992 (+)NCBIUU_Cfam_GSD_1.0
Igbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X47,530,398 - 47,557,161 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367621,292,572 - 1,319,145 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X56,173,773 - 56,206,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X63,371,489 - 63,403,353 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IGBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X59,970,740 - 60,008,066 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX59,971,234 - 60,008,047 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660651,827,501 - 1,859,929 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462490371,212 - 94,470 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Igbp1
26 total Variants

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:141
Interacting mature miRNAs:159
Transcripts:ENSRNOT00000057900
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X5704214165612192Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

RH129961  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X65,604,760 - 65,604,978 (+)MAPPERmRatBN7.2
Rnor_6.0X70,344,688 - 70,344,905NCBIRnor6.0
Rnor_5.0X71,216,640 - 71,216,857UniSTSRnor5.0
RGSC_v3.4X88,506,737 - 88,506,954UniSTSRGSC3.4
CeleraX65,964,168 - 65,964,385UniSTS
Cytogenetic MapXq31UniSTS
AW208785  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X65,604,709 - 65,604,825 (+)MAPPERmRatBN7.2
Rnor_6.0X70,344,637 - 70,344,752NCBIRnor6.0
Rnor_5.0X71,216,589 - 71,216,704UniSTSRnor5.0
RGSC_v3.4X88,506,686 - 88,506,801UniSTSRGSC3.4
CeleraX65,964,117 - 65,964,232UniSTS
Cytogenetic MapXq31UniSTS
RH135891  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X69,622,950 - 69,623,118 (+)Marker Load Pipeline
mRatBN7.2X65,582,856 - 65,583,025 (+)MAPPERmRatBN7.2
Rnor_6.0X70,322,789 - 70,322,957NCBIRnor6.0
Rnor_5.0X71,194,742 - 71,194,910UniSTSRnor5.0
CeleraX65,942,268 - 65,942,436UniSTS
Cytogenetic MapXq31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000057900   ⟹   ENSRNOP00000054708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX65,582,821 - 65,606,049 (+)Ensembl
Rnor_6.0 EnsemblX70,322,755 - 70,345,005 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX70,330,198 - 70,344,747 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX70,332,936 - 70,344,879 (+)Ensembl
RefSeq Acc Id: NM_031624   ⟹   NP_113812
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X69,622,925 - 69,645,167 (+)NCBI
mRatBN7.2X65,582,832 - 65,605,078 (+)NCBI
Rnor_6.0X70,322,764 - 70,345,005 (+)NCBI
Rnor_5.0X71,194,717 - 71,216,957 (+)NCBI
RGSC_v3.4X88,490,498 - 88,507,054 (+)RGD
CeleraX65,942,243 - 65,964,485 (+)RGD
Sequence:
Protein RefSeqs NP_113812 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD05364 (Get FASTA)   NCBI Sequence Viewer  
  AAH68202 (Get FASTA)   NCBI Sequence Viewer  
  EDL95938 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000054708
  ENSRNOP00000054708.3
GenBank Protein O08836 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113812   ⟸   NM_031624
- UniProtKB: O08836 (UniProtKB/Swiss-Prot),   A6IQ75 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054708   ⟸   ENSRNOT00000057900
UIM

Name Modeler Protein Id AA Range Protein Structure
AF-O08836-F1-model_v2 AlphaFold O08836 1-340 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701864
Promoter ID:EPDNEW_R12388
Type:multiple initiation site
Name:Igbp1_1
Description:immunoglobulin binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X70,322,765 - 70,322,825EPDNEW


1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-2133 BioCyc
Ensembl Genes ENSRNOG00000026267 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000057900 ENTREZGENE
  ENSRNOT00000057900.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.540 UniProtKB/Swiss-Prot
  6.10.250.1140 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6921265 IMAGE-MGC_LOAD
InterPro TAP42/TAP46-like_sf UniProtKB/Swiss-Prot
  TAP46-like UniProtKB/Swiss-Prot
KEGG Report rno:58845 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72768 IMAGE-MGC_LOAD
NCBI Gene 58845 ENTREZGENE
PANTHER IMMUNOGLOBULIN-BINDING PROTEIN 1 UniProtKB/Swiss-Prot
  PTHR10933 UniProtKB/Swiss-Prot
Pfam TAP42 UniProtKB/Swiss-Prot
PhenoGen Igbp1 PhenoGen
RatGTEx ENSRNOG00000026267 RatGTEx
TIGR TC229471
UniProt A6IQ75 ENTREZGENE, UniProtKB/TrEMBL
  IGBP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-01 Igbp1  immunoglobulin binding protein 1  Igbp1  immunoglobulin (CD79A) binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Igbp1  immunoglobulin (CD79A) binding protein 1    immunoglobulin binding protein 1   Name updated 1299863 APPROVED
2002-06-10 Igbp1  immunoglobulin binding protein 1       Name updated 70584 APPROVED

Note Type Note Reference
gene_regulation expression is responsive to prolactin 61637