Igbp1 (immunoglobulin binding protein 1)

Gene: Igbp1 (immunoglobulin binding protein 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Igbp1

Name:

immunoglobulin binding protein 1

RGD ID:

12638132

Description:

ENCODES a protein that exhibits protein phosphatase 2A binding (ortholog); protein phosphatase regulator activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN negative regulation of apoptotic signaling pathway (ortholog); negative regulation of stress-activated MAPK cascade (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); microtubule (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

immunoglobulin (CD79A) binding protein 1; immunoglobulin-binding protein 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	47,530,398 - 47,557,161 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936762	1,292,572 - 1,319,145 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Breast Neoplasms (ISO)

corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Lung Neoplasms (ISO)

Neoplastic Cell Transformation (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of apoptotic signaling pathway (IEA,ISO)

negative regulation of protein dephosphorylation (IEA)

negative regulation of stress-activated MAPK cascade (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of dephosphorylation (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

regulation of dephosphorylation (IEA)

regulation of microtubule-based movement (ISO)

regulation of signal transduction (IEA)

response to interleukin-1 (ISO)

response to tumor necrosis factor (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

microtubule (IEA)

Molecular Function

enzyme binding (IEA)

mitogen-activated protein kinase kinase binding (IEA)

protein binding (ISO)

protein domain specific binding (IEA)

protein phosphatase 2A binding (IEA,ISO)

protein phosphatase regulator activity (ISO)

protein-containing complex binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Igbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	47,530,398 - 47,557,161 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936762	1,292,572 - 1,319,145 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IGBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	70,133,447 - 70,166,324 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	70,133,447 - 70,166,324 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	69,353,297 - 69,386,174 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	69,270,043 - 69,302,899 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	69,136,338 - 69,169,192	NCBI
Celera	X	69,706,683 - 69,739,540 (+)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	63,174,076 - 63,207,564 (+)	NCBI		HuRef
CHM1_1	X	69,246,939 - 69,279,788 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	68,566,802 - 68,599,681 (+)	NCBI		T2T-CHM13v2.0

Igbp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	99,537,897 - 99,559,731 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	99,537,897 - 99,559,731 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	100,494,291 - 100,516,125 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	100,494,291 - 100,516,125 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	97,689,630 - 97,711,464 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	96,697,064 - 96,718,720 (+)	NCBI		MGSCv36	mm8
Celera	X	87,420,356 - 87,442,287 (+)	NCBI		Celera
Cytogenetic Map	X	C3	NCBI
cM Map	X	43.72	NCBI

Igbp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	69,622,925 - 69,645,167 (+)	NCBI		GRCr8
mRatBN7.2	X	65,582,832 - 65,605,078 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	65,582,821 - 65,606,049 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,066,253 - 67,088,494 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	70,566,639 - 70,588,880 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,127,540 - 68,149,782 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	70,322,764 - 70,345,005 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	70,322,755 - 70,345,005 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	71,194,717 - 71,216,957 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	88,490,498 - 88,507,054 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	88,566,669 - 88,580,484 (+)	NCBI
Celera	X	65,942,243 - 65,964,485 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

Igbp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955475	9,671,162 - 9,694,926 (+)	NCBI	ChiLan1.0	ChiLan1.0

IGBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	69,810,161 - 69,843,192 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	69,813,728 - 69,846,794 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	59,401,426 - 59,434,363 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	69,460,736 - 69,493,616 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	69,460,734 - 69,493,616 (+)	Ensembl	panpan1.1		panPan2

IGBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	54,558,515 - 54,612,029 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	54,547,446 - 54,613,171 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	45,384,171 - 45,437,674 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	55,524,457 - 55,577,975 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	55,513,867 - 55,579,130 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	53,493,501 - 53,547,031 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	54,824,297 - 54,877,823 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	54,751,460 - 54,804,992 (+)	NCBI		UU_Cfam_GSD_1.0

IGBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	56,173,773 - 56,206,121 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	63,371,489 - 63,403,353 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IGBP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	59,970,740 - 60,008,066 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	59,971,234 - 60,008,047 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	1,827,501 - 1,859,929 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Igbp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624903	71,212 - 94,470 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013365045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013365045 ⟹ XP_013220499

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	47,530,398 - 47,557,152 (-)	NCBI
SpeTri2.0	NW_004936762	1,292,572 - 1,319,145 (-)	NCBI

Sequence:

show sequence

CTTCAAACTCACGCCACAGGTCCGGCGAACCGTGATTGTGGCACGGCGACCTGAGCAACTGGCT
GCCCGGACTCCTCAACTTGGGGAGCAACTTGCGAGATGCCTACAACTTTTAACACGCTGCCTGG
CAAAATGGCTCTATGGAAACTCCGTTGCTAGGGCCGGCAAACGGCGGCTCCCGGAAGTCCCTTG
ACGTTTTTGTAACAATTAAGCGACTGGCCAATGCGACGCCACTTCCGGTGTCGTAAGGGCTCTC
GGAATTCTCCTTTACAAAGATTGCCTTTGACCCCGGAAGTGAGGTCTTCCGGGTTCCTCCCTCC
CCCAAGATGGCTGCGTCTGAAGACGAGTTAGAGCTGCCCCGGCTTCCCGAGTTGTTCGAAACCA
GCCGGAAGCTTCTGGATGAAGTGGAAGTAGCGATTGAACCCAGCGGTTCCCGGATGGTTCAAGA
TAAGGTGTTAAAGGCACTGGACCTCCTTGAGAAGGCTACCGAAATGTTATCACAGCTTGATTTG
TTCAGCCGAAATGAAGATTTGGAAGAGATTGCTTCCACCGACTTGAAGTACCTGATGGTGCCAG
CGTTTCAAGGAGCCCTCACCATGAAACAAGTGAACCCCAGCAAGCGTCTAGAGCATTTACAGCA
AGCTCGAGAACACTTTATAAACTTCTTAACCCAGTGCCATTACTATCATGTGGCACGGTTTCAG
CTGCCCAAAACCAAGAACAACTCAGCTGAAAATAATACTGCTAGTTCCTCCATGGCCTATCCTA
GCCTCGTTGCTATGGCATCTCAAAGACAGGCTAAAATAGAGAGATACAAGCAGAAGAAGGAGGT
GGAGCATAGGTTGTCTACACTGAAATCTGCTGTGGAAAGTGGTCAAGCAGATGATGAACGTGTT
CGTGAATATAACCTCCTTCAGCTTCGGAGGTGGATTGGTATCAGCTTAGAAGAGATTGAGAGCA
TTGACCAGGAAATAAAGATCCTGAGAGAAAAAGACTCTTCAAGAGAGGCATCAACTTCTCACCC
AGAGTCTCTTCAGGAGAGGCCTCCAATGAAACCCTTCGTACTTACTCGGAACAAGGCCCAAGCC
AAAGTATTTGGAGCTGGTTATCCAAGTCTGGCAACTATGACAGTAAGTGACTGGTATGAGCAGC
ATCGAAAATATGGAGCATTACCAGATCAAGGAATAGCCAAAGCAACATCAGCTGAATTCAAAAG
GACAGCTCAGCAACAGGAAGATCAAGAAAAAAAGGAAGAAGAGGATGATGAGAAAACAATCCAC
AGAGCAAGGGAGTGGGATGATTGGAAGGATACCCATCCTAGGGGCTATGGCAACCGACAGAACA
TGGGCTAATCTTCCCAGGACACAACAGGACTTTGGGGCACGTGCCTTCTCTGCCAAGGAAAACT
GTGCCGCCTTCCCTTCCCTGGGCTACTGCTTCGGCTGTGTGCAACGAAGGCAAAGATGCTGAAT
CTTGCTTTGCTTTCAATAAAGTGTCAAACAATTAAGTGTGTATTTGTACCCTAGATAATGACCA
GTGATCTTGTTTTGACATTACTAATTCTCATCATGGTGTATTCCGATTTCTTAAGTGGACAGAA
AAGAGCACTGAGAATTGGCTCTGTATAATCAATGCTGTAATGAATTATCTTAAATATAATAAAA
TCCATTCTATTACATGAGGCTGTGCAGAAA

hide sequence

RefSeq Acc Id:

XM_040282075 ⟹ XP_040138009

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	47,541,166 - 47,557,161 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_013220499	(Get FASTA)	NCBI Sequence Viewer
	XP_040138009	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000015741.1
GenBank Protein	KAG3272398	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_013220499 ⟸ XM_013365045
- Peptide Label:	isoform X1
- UniProtKB:	I3MUE6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAASEDELELPRLPELFETSRKLLDEVEVAIEPSGSRMVQDKVLKALDLLEKATEMLSQLDLFS RNEDLEEIASTDLKYLMVPAFQGALTMKQVNPSKRLEHLQQAREHFINFLTQCHYYHVARFQLP KTKNNSAENNTASSSMAYPSLVAMASQRQAKIERYKQKKEVEHRLSTLKSAVESGQADDERVRE YNLLQLRRWIGISLEEIESIDQEIKILREKDSSREASTSHPESLQERPPMKPFVLTRNKAQAKV FGAGYPSLATMTVSDWYEQHRKYGALPDQGIAKATSAEFKRTAQQQEDQEKKEEEDDEKTIHRA REWDDWKDTHPRGYGNRQNMG hide sequence

RefSeq Acc Id:	XP_040138009 ⟸ XM_040282075
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000025956	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000028160.2	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.540	UniProtKB/TrEMBL
	6.10.250.1140	UniProtKB/TrEMBL
InterPro	TAP42/TAP46-like_sf	UniProtKB/TrEMBL
	TAP46-like	UniProtKB/TrEMBL
NCBI Gene	Igbp1	ENTREZGENE
PANTHER	IMMUNOGLOBULIN (CD79A)-BINDING PROTEIN 1	UniProtKB/TrEMBL
	PTHR10933	UniProtKB/TrEMBL
Pfam	TAP42	UniProtKB/TrEMBL
UniProt	I3MUE6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - OMIM