Bp56 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp56 (Blood pressure QTL 56) Rattus norvegicus

Symbol: Bp56
Name: Blood pressure QTL 56
RGD ID: 70221
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 4.9
P Value: Not Available
Variance: 6.1
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X61,398,097 - 70,352,120RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X61,984,911 - 71,224,072RGDRnor5.0
RGSC_v3.4X79,626,109 - 88,514,168RGDRGSC3.4
RGSC_v3.1X79,699,401 - 88,587,601RGD
Cross Type: F2
Strains Crossed: SBH/Ygl SBN/Ygl 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
SBH/Ygl  (IEA)
SBN/Ygl  (IEA)

References

References - curated
1. QTL data import from the RatMap database
2. Yagil C, etal., Hypertension 1999 Jan;33(1 Pt 2):261-5.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2540Efnb1ephrin B1X6889122768904034Rat
70898Maged1MAGE family member D1X6380319463809715Rat
62011Igbp1immunoglobulin binding protein 1X7032276470345005Rat
2147Arandrogen receptorX6765625367828998Rat
71060HephhephaestinX6537731365658479Rat
621260MsnmoesinX6522683465294192Rat
620719Arhgef9Cdc42 guanine nucleotide exchange factor 9X6424957664428444Rat
621816Pola1DNA polymerase alpha 1, catalytic subunitX6238260462698830Rat
708434Pcyt1bphosphate cytidylyltransferase 1B, cholineX6272769162821199Rat
1563909LOC367830similar to FAM48A proteinX6306495063115272Rat
1565054RGD1565054similar to 60S acidic ribosomal protein P1X6467621364679280Rat
1565058RGD1565058similar to RIKEN cDNA 1700019M22X6651592866516694Rat
1561708Zc4h2zinc finger C4H2-type containingX6488797864908682Rat
1563178Edaectodysplasin-AX6973012370222693Rat
1565755Las1lLAS1-like, ribosome biogenesis factorX6508159165102344Rat
1564004Spin4spindlin family, member 4X6421707464221225Rat
1561142Asb12ankyrin repeat and SOCS box-containing 12X6471433764800662Rat
1562664Zfxzinc finger protein X-linkedX6315836863204971Rat
1565657RGD1565657similar to germ cell-lessX6403467064036266Rat
1560770Stard8StAR-related lipid transfer domain containing 8X6871315768785046Rat
1563213Gspt2G1 to S phase transition 2X6395913163961652Rat
1563355Zxdbzinc finger, X-linked, duplicated BX6409260964097967Rat
1560322Amer1APC membrane recruitment protein 1X6468662064702504Rat
1566100RGD1566100similar to Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma)X6332935563333352Rat
1587609LOC688570similar to butyrate-induced transcript 1X6683689066847667Rat
1562685Pgr15lG protein-coupled receptor 15-likeX6631441666319928Rat
1560891Zc3h12bzinc finger CCCH-type containing 12BX6504003265074857Rat
1586617LOC686079similar to discs, large homolog-associated protein 4X6501239565016649Rat
1583766LOC367842similar to eukaryotic translation termination factor 1X6666720166668735Rat
1584125Fam155bfamily with sequence similarity 155, member BX6957996869605032Rat
1585224Rpl27-l1ribosomal protein L27-like 1X6895502568955506Rat
1585233LOC688775similar to 40S ribosomal protein SA (p40) (34/67 kDa laminin receptor)X6887382968877240Rat
1562672Arxaristaless related homeoboxX6236375762376139Rat
1565289Apooapolipoprotein OX6352103363625134Rat
1561086Rpl34l1ribosomal protein L34-like1X6650060466500967Rat
1565951Fam48b1family with sequence similarity 48, member B1X6300032263006722Rat
1564025Eda2rectodysplasin A2 receptorX6656020066602509Rat
1563322RGD1563322similar to heat shock protein 1, betaX6368292063684683Rat
1560855Otud6aOTU deubiquitinase 6AX7025629970257746Rat
1563101Klhl15kelch-like family member 15X6334227763390915Rat
1565111Awat2acyl-CoA wax alcohol acyltransferase 2X7022476170233021Rat
1561658RGD1561658similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)X6721055167212559Rat
1564534RGD1564534similar to CHCHD4 proteinX6305303163059164Rat
1561279Eif2s3eukaryotic translation initiation factor 2 subunit gammaX6326810663291125Rat
1563435Ophn1oligophrenin 1X6818586568579518Rat
1564566Gpr165G protein-coupled receptor 165X6579635965802144Rat
1564659Vsig4V-set and immunoglobulin domain containing 4X6537085165400298Rat
1566154Yipf6Yip1 domain family, member 6X6862576068637780Rat
1590267LOC685700hypothetical protein LOC685700X6345234563520836Rat
1593786LOC685471similar to 2,4-dienoyl CoA reductase 1, mitochondrialX6297685362979845Rat
1590231LOC685737similar to L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M)X6369147763692530Rat
1591532Pja1praja ring finger ubiquitin ligase 1X6921364569218601Rat
1588547LOC314123similar to Aspartate aminotransferase, mitochondrial precursor (Transaminase A) (Glutamate oxaloacetate transaminase 2)X6491389664915954Rat
1589066LOC685820similar to queuine tRNA-ribosyltransferase domain containing 1X6398402963985373Rat
1587824LOC685950similar to Mitochondrial carrier protein CGI-69X6452801764529187Rat
1584810LOC679731hypothetical protein LOC679731X6472142264722660Rat
1586626LOC686070similar to Alpha- and gamma-adaptin-binding protein p34X6738601267387060Rat
1589276LOC683205hypothetical protein LOC683205X6295909262959934Rat
1595135LOC685313similar to eukaryotic translation initiation factor 4BX6191875061919994Rat
1593274LOC296875similar to Alpha-enolase (2-phospho-D-glycerate hydro-lyase) (Non-neural enolase) (NNE) (Enolase 1)X6798031567981646Rat
1593276Pdk3pyruvate dehydrogenase kinase 3X6283613162904114Rat
1597149LOC312111similar to prohibitinX6858092268585216Rat
1591335LOC685678similar to solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21X6343129363432176Rat
2320274LOC100361391hypothetical LOC100361391X6955812169559620Rat
2322061LOC100360495hypothetical LOC100360495X6736190967362171Rat
2320547LOC100361216deoxycytidylate deaminase-likeX6808869568118056Rat
2321327LOC100360831hypothetical LOC100360831X6555677065558142Rat
2322817LOC100363530hypothetical LOC100363530X6203514762047042Rat
2321468LOC100360790heat shock transcription factor 3X6541224165468572Rat
2322848Gpx2-ps2glutathione peroxidase 2, pseudogene 2X6382078663824748Rat
2322260LOC100360393hypothetical LOC100360393X6450657764507748Rat
2322893LOC100360052splicing factor, arginine/serine-rich 10-likeX6369970763700414Rat
2323249LOC100359894hypothetical LOC100359894X6303118663031671Rat
2325543Mir223microRNA 223X6536781265367921Rat
4888534Mir3573microRNA 3573X6889297268893043Rat
6494769LOC100911168kelch-like protein 15-likeX6339220963397468Rat
7509912LOC102551431profilin-2-likeX6729439567294787Rat
7539044LOC10254652160S ribosomal protein L15-likeX6382082063821427Rat
7666182LOC102551494zinc transporter 9-likeX6251802762520604Rat
7626838LOC102551035serine/arginine repetitive matrix protein 4-likeX6533531665336069Rat
7609486LOC102551429uncharacterized LOC102551429X6217044762318636Rat
7616550LOC102556301RWD domain-containing protein 4-likeX6353822963539244Rat
7570644LOC102550969uncharacterized LOC102550969X6510655065112159Rat
7551563LOC102554251ubiquitin-conjugating enzyme E2 variant 1-likeX6310756563108065Rat
7692727LOC102546630protein gar2-likeX6399881363999664Rat
7678081LOC102555722ER membrane protein complex subunit 7-likeX6878398368787651Rat
7733257LOC102556393uncharacterized LOC102556393X6363109763656994Rat
7740156LOC102551847uncharacterized LOC102551847X6847367368481194Rat
7722908LOC102555363transcription factor Sp3-likeX6846769868471989Rat
7682302LOC10255026240S ribosomal protein SA-likeX6480028264801197Rat
9232671LOC10369084660 kDa heat shock protein, mitochondrial pseudogeneX6563673465641849Rat
9234313LOC103690847ubiquitin-like protein ATG12 pseudogeneX6546185665463737Rat
9396441LOC10369086214-3-3 protein sigma-likeX6310206363106317Rat
9476443LOC103694487protein gar2-likeX6389738863898284Rat
9457454LOC103690848developmental pluripotency-associated protein 4-likeX6974197069747095Rat
9685079Mir676microRNA 676X7020701570207103Rat
11373169LOC108349231glyceraldehyde-3-phosphate dehydrogenase pseudogeneX7023401770235241Rat
11380413LOC108349227glyceraldehyde-3-phosphate dehydrogenase pseudogeneX6647408466475078Rat
11467816LOC108349226CDGSH iron-sulfur domain-containing protein 3, mitochondrial-likeX6555753365558148Rat
11362609LOC108349222uncharacterized LOC108349222X6167071861815532Rat
11450976LOC108349229uncharacterized LOC108349229X6920705669209244Rat
11365249LOC108349172zinc finger protein 431-likeX7031160570312055Rat
11442080LOC10834923060S ribosomal protein L29 pseudogeneX6971738669717914Rat
11453342LOC108349169glyceraldehyde-3-phosphate dehydrogenase-likeX6343910263440163Rat
11432872LOC10834917040S ribosomal protein S10 pseudogeneX6418208964182629Rat
11375853LOC108349225uncharacterized LOC108349225X6365807263665457Rat
11400519LOC108353266suprabasin-likeX6300420563006432Rat
11403019LOC108349224ribosome biogenesis protein NSA2 homologX6274233262745981Rat
11504987LOC108349228uncharacterized LOC108349228X6641225966434239Rat
11508574LOC108349223zinc transporter 9 pseudogeneX6251178462521982Rat
11516141LOC108349130small nuclear ribonucleoprotein F-likeX6311271963113009Rat
11489255LOC10834910860S ribosomal protein L7 pseudogeneX6839015168409280Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10185DXWox9106X6765775067657855Ratregion
10186DXMgh11218X6765390967654115Ratregion
33788DXMit6126X6320476163204971Ratregion
34192DXMgh9145X7035212070352264Ratregion
33717DXMit4197X6139790561398097Ratregion
37338DXRat30219X6489261064892822Ratregion
35561DXRat16127X6663051466630639Ratregion
37056DXRat31130X6854458668544715Ratregion
39810DXRat113233X6891895368919185Ratregion
38042DXRat56180X6310974663109925Ratregion
38500DXRat57223X6524074565240961Ratregion
39368DXRat65241X6323700163237257Ratregion
39392DXRat91135X6716811667168234Ratregion
40840DXRat89201X6409799464098202Ratregion
43156DXRat133200X6482732064827524Ratregion
62521DXUia3167X6201022462010387Ratregion
1630353DXGot133148X6283789962838046Ratregion
1629934DXGot137274X6792142967921702Ratregion
1639889DXGot192185X6975247369752657Ratregion
1636396DXGot136169X6488668864886856Ratregion
1636516DXGot127198X6869608168696278Ratregion
1637904DXGot151291X6557143765571727Ratregion
1638010DXGot146202X6139790361398104Ratregion
5035781PMC169877P1531X6847139768471934Ratregion
7206520UniSTS:5468500X6380666163808193Ratregion
5036267Maged1173X6380322763803399Ratregion
7206164UniSTS:532310414X6237569762376110Ratregion
5026552RH132649180X6315865263158831Ratregion
5026614RH132880196X6238287562383070Ratregion
5035070D7S2869105X6332954163329645Ratregion
5027555AI035637202X6283667462836875Ratregion
5028324POLYa343X6188158261881924Ratregion
5053715RH142809163X6818597268186134Ratregion
5055821RH144022256X6580429965804553Ratregion
7192142Ar188X6781584467816031Ratregion
5051617AW208785116X7034463770344752Ratregion
5043656RH130151193X6488816564888357Ratregion
5044490RH130633196X6565824065658435Ratregion
5049098RH133284189X6863737068637558Ratregion
5049326RH133416182X6353828863538482Ratregion
5039986RH128023196X6283657062836765Ratregion
5043324RH129961218X7034468870344905Ratregion
5039978RH128018181X6529548065295660Ratregion
5041052RH128635210X6471437264714581Ratregion
5043094RH129829212X6421717164217382Ratregion
5041480RH128881211X6921372069213930Ratregion
5041568RH128932199X6237591362376111Ratregion
5072712RH137009199X6192008461920285Ratregion
5075178RH138443243X6409454964094791Ratregion
5078166RH140181206X6921372069213925Ratregion
5072972RH137160206X6921406569214270Ratregion
5071880RH135338194X6468460764684800Ratregion
5066788AU048150202X6154022761540428Ratregion
5067718AU047577200X6475639464756954Ratregion
5067718AU047577200X6475639464756595Ratregion
5070073RH94457165X6491369264913856Ratregion
5069772AU028844207X6465443364654634Ratregion
5060316AW531358193X6315929963159491Ratregion
5062396BE106637164X6818931668189479Ratregion
5060714BE104365189X6354583563546023Ratregion
5065888AA964352208X6890370868903915Ratregion
5065906BE116041157X6424900164249157Ratregion
5061154BI293172114X6348331663483429Ratregion
5063214BI301442218X6320546963205686Ratregion
5087544PMC305603P1212X6847022668470438Ratregion
5087698Ar955X6765783767658791Ratregion
5090615AU049858220X6139787961398098Ratregion
5090257AU049644282X7014027370140554Ratregion
5084752AI179266140X6305896663059105Ratregion
5087700UniSTS:14112064X6765833167658394Ratregion
5090677AU049895288X6334885263349139Ratregion
5090323AU049683203X6922152169221730Ratregion
5088637AU048688229X6345727163457499Ratregion
5090197AU049608155X6277727862777432Ratregion
5081084RH141955180X6326712863267307Ratregion
5081471AA998497191X6380323163803630Ratregion
5081489AA998661117X6819642668196542Ratregion
5503200mZfa461X6316276263163222Ratregion
5504496PMC24264P3112X7013131370131424Ratregion
5504498PMC24264P4146X7021889670219041Ratregion
5504516PMC262401P2224X6320475663204979Ratregion
5504560PMC304104P1559X6765729767657855Ratregion
5506296D17S895E98X6858101968581116Ratregion
5499621MARC_3162-3163:991936817:10X6452842864528683Ratregion
5500304GDB:176286467X6765749667657962Ratregion
5500334GDB:194743445X6765751867657962Ratregion
5502829EDA2R674X6656715266567825Ratregion
5502842Arx873X6237523862376110Ratregion
5500531RH135891169X7032278970322957Ratregion
5500711RH79934191X6666720966667399Ratregion
5503758Pcyt1b71X6275458562754655Ratregion
5501283RH176271183X6327392863275110Ratregion
5504714PMC64995P1369X6765729067657658Ratregion
5506531EFNB1_609672X6890266568903336Ratregion
5502823EIF2S3105X6327506063275164Ratregion
Position Markers

Flank 1: (DXMgh9)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X70,352,120 - 70,352,264NCBI
Rnor_5.0X71,224,072 - 71,224,216UniSTS
RGSC_v3.4X88,514,168 - 88,514,313RGD
RGSC_v3.4X88,514,169 - 88,514,313UniSTS
RGSC_v3.1X88,587,601 - 88,587,746RGD
CeleraX65,971,600 - 65,971,744UniSTS
Cytogenetic MapX RGD
Peak: (DXRat15)
Rat AssemblyChrPosition (strand)Source
Rnor_5.0X65,347,434 - 65,347,605NCBI
RGSC_v3.4X82,772,498 - 82,772,668RGD
RGSC_v3.1X82,845,790 - 82,845,960RGD
Cytogenetic MapX RGD
Flank 2: (DXMit4)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X61,397,905 - 61,398,097NCBI
Rnor_5.0X61,984,719 - 61,984,911UniSTS
RGSC_v3.4X79,625,917 - 79,626,109UniSTS
RGSC_v3.4X79,625,916 - 79,626,109RGD
RGSC_v3.1X79,699,208 - 79,699,401RGD
CeleraX57,486,791 - 57,486,983UniSTS
SHRSP x BN MapX17.21UniSTS
SHRSP x BN MapX17.21RGD
FHH x ACI MapX21.3199RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1815335263153352Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6139809770352120Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X70352120127888215Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Bp56

RGD Curation Notes
Note Type Note Reference
null number of animals used: 707 F2 animals 69713
null software used: MAPMAKER/QTL 69713
null measurement method: basal blood pressure was measured at 6 weeks then 1%NaCl was given in drinking water; after 4 weeks systolic blood pressure was measured 69713
qtl_general QTL identifies a region containing a gene or genes that contribute to salt susceptibility in females but not in males 69713