Gene: Itpr2 (inositol 1,4,5-trisphosphate receptor, type 2) Rattus norvegicus
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Symbol:
Itpr2
Name:
inositol 1,4,5-trisphosphate receptor, type 2
Description:
Exhibits calcium ion binding activity; inositol 1,4,5 trisphosphate binding activity; and inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. Involved in cellular response to hypoxia and release of sequestered calcium ion into cytosol. Localizes to several cellular components, including the endoplasmic reticulum membrane; myelin sheath; and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and isolated anhidrosis with normal sweat glands. Orthologous to human ITPR2 (inositol 1,4,5-trisphosphate receptor type 2); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
inositol 1,4,5-triphosphate receptor 2; inositol 1,4,5-triphosphate receptor type 2; inositol 1,4,5-triphosphate receptor, type 2; inositol 1,4,5-trisphosphate receptor type 2; inositol 145-triphosphate receptor type 2; inositol triphosphate receptor type 2; insP3R2; IP3 receptor; IP3R 2; type 2 inositol 1,4,5-trisphosphate receptor; type 2 InsP3 receptor
Orthologs:
Homo sapiens
(human) : ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
HGNC
Alliance
Itpr2 (inositol 1,4,5-triphosphate receptor 2)
MGI
Alliance
Itpr2 (inositol 1,4,5-trisphosphate receptor type 2)
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
Itpr2 (inositol 1,4,5-trisphosphate receptor type 2)
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
more info ...
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2) HGNC
HomoloGene, NCBI, Panther
Mus musculus (house mouse):
Itpr2 (inositol 1,4,5-triphosphate receptor 2) HGNC
NCBI, HomoloGene, Panther
Chinchilla lanigera (long-tailed chinchilla):
Itpr2 (inositol 1,4,5-trisphosphate receptor type 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Itpr2 (inositol 1,4,5-trisphosphate receptor type 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
ITPR3 (inositol 1,4,5-trisphosphate receptor type 3) HGNC
OrthoMCL
Homo sapiens (human):
ITPR1 (inositol 1,4,5-trisphosphate receptor type 1) HGNC
OrthoDB
Alliance orthologs 3
Homo sapiens (human):
ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
Alliance
DIOPT (HGNC, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Mus musculus (house mouse):
Itpr2 (inositol 1,4,5-triphosphate receptor 2)
Alliance
DIOPT (Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Danio rerio (zebrafish):
itpr2 (inositol 1,4,5-trisphosphate receptor, type 2)
Alliance
DIOPT (OrthoFinder, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):
itr-1
Alliance
DIOPT (Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):
Itp-r83A
Alliance
DIOPT (Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 4 180,423,452 - 180,800,088 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 4 180,538,389 - 180,722,358 (-) Ensembl Rnor_5.0 4 244,585,711 - 244,960,429 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 4 183,677,606 - 184,066,130 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 4 183,922,730 - 184,311,254 (-) NCBI Celera 4 167,526,971 - 167,901,481 (-) NCBI Celera Cytogenetic Map 4 q44 NCBI RH 3.4 Map 4 1070.3 RGD
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
Familial Generalized Anhidrosis with Abnormal or Absent Sweat Glands ISO RGD:734228 8554872 ClinVar Annotator: match by term: Anhidrosis, familial generalized, with normal sweat glands ClinVar PMID:25329695 isolated anhidrosis with normal sweat glands ISO RGD:734228 8554872 ClinVar Annotator: match by term: Anhidrosis, isolated, with normal sweat glands ClinVar PMID:25329695
Imported Annotations - CTD
Brain Hypoxia ISO RGD:734228 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17285299 Cardiomegaly ISO RGD:734228 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:20616315 Imported Annotations - OMIM
isolated anhidrosis with normal sweat glands ISO RGD:734228 7240710 OMIM
(-)-epigallocatechin 3-gallate increases expression ISO RGD:734228 6480464 epigallocatechin gallate results in increased expression of ITPR2 mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:734228 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ITPR2 mRNA CTD PMID:22079256 1,1-dichloroethene decreases expression ISO RGD:737250 6480464 vinylidene chloride results in decreased expression of ITPR2 mRNA CTD PMID:26682919 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:737250 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ITPR2 gene] CTD PMID:20819909 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737250 6480464 Tetrachlorodibenzodioxin results in decreased expression of ITPR2 mRNA CTD PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:734228 6480464 Tetrachlorodibenzodioxin results in decreased expression of ITPR2 mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:737250 6480464 Tetrachlorodibenzodioxin affects the expression of ITPR2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:737250 6480464 Tetrachlorodibenzodioxin results in increased expression of ITPR2 mRNA CTD PMID:17035482 , PMID:20819909 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA CTD PMID:23537331 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of ITPR2 mRNA CTD PMID:21346803 2-butoxyethanol decreases expression ISO RGD:737250 6480464 n-butoxyethanol results in decreased expression of ITPR2 mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression ISO RGD:734228 6480464 Lactic Acid results in increased expression of ITPR2 mRNA CTD PMID:30851411 4,4'-sulfonyldiphenol increases expression ISO RGD:737250 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of ITPR2 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide increases expression ISO RGD:737250 6480464 Fenretinide results in increased expression of ITPR2 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ITPR2 mRNA CTD PMID:24780913 acetazolamide increases expression ISO RGD:737250 6480464 Acetazolamide results in increased expression of ITPR2 mRNA CTD PMID:19274763 Adenophostin A multiple interactions ISO RGD:737250 6480464 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] more ... CTD PMID:15201137 Adenophostin A increases activity ISO RGD:737250 6480464 adenophostin A results in increased activity of ITPR2 protein CTD PMID:15201137 aflatoxin B1 increases expression ISO RGD:737250 6480464 Aflatoxin B1 results in increased expression of ITPR2 mRNA CTD PMID:19770486 aflatoxin B1 decreases methylation ISO RGD:734228 6480464 Aflatoxin B1 results in decreased methylation of ITPR2 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:734228 6480464 Aflatoxin B1 results in decreased expression of ITPR2 mRNA CTD PMID:22100608 aflatoxin B2 increases methylation ISO RGD:734228 6480464 aflatoxin B2 results in increased methylation of ITPR2 intron CTD PMID:30157460 aflatoxin M1 decreases expression ISO RGD:734228 6480464 Aflatoxin M1 results in decreased expression of ITPR2 mRNA CTD PMID:30928695 all-trans-retinoic acid affects expression ISO RGD:734228 6480464 Tretinoin affects the expression of ITPR2 mRNA CTD PMID:15498508 all-trans-retinoic acid increases expression ISO RGD:734228 6480464 Tretinoin results in increased expression of ITPR2 mRNA, Tretinoin results in increased expression of ITPR2 protein CTD PMID:15894607 , PMID:30093655 antirheumatic drug decreases expression ISO RGD:734228 6480464 Antirheumatic Agents results in decreased expression of ITPR2 mRNA CTD PMID:24449571 arsane affects methylation ISO RGD:734228 6480464 Arsenic affects the methylation of ITPR2 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:734228 6480464 Arsenic affects the methylation of ITPR2 gene CTD PMID:25304211 arsenous acid multiple interactions ISO RGD:737250 6480464 Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ITPR2 mRNA] CTD PMID:29095437 arsenous acid increases expression ISO RGD:734228 6480464 Arsenic Trioxide results in increased expression of ITPR2 protein CTD PMID:30093655 arsenous acid decreases expression ISO RGD:737250 6480464 Arsenic Trioxide results in decreased expression of ITPR2 mRNA CTD PMID:29095437 benzo[a]pyrene multiple interactions ISO RGD:737250 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to ITPR2 promoter] CTD PMID:19654925 benzo[a]pyrene affects methylation ISO RGD:734228 6480464 Benzo(a)pyrene affects the methylation of ITPR2 intron CTD PMID:30157460 benzo[a]pyrene decreases expression ISO RGD:734228 6480464 Benzo(a)pyrene results in decreased expression of ITPR2 mRNA CTD PMID:20064835 more ... benzo[a]pyrene decreases expression ISO RGD:737250 6480464 Benzo(a)pyrene results in decreased expression of ITPR2 mRNA CTD PMID:19770486 , PMID:21715664 benzo[e]pyrene decreases methylation ISO RGD:734228 6480464 benzo(e)pyrene results in decreased methylation of ITPR2 intron CTD PMID:30157460 bis(2-chloroethyl) sulfide decreases expression ISO RGD:737250 6480464 Mustard Gas results in decreased expression of ITPR2 mRNA CTD PMID:15674843 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ITPR2 mRNA CTD PMID:30816183 butanal decreases expression ISO RGD:734228 6480464 butyraldehyde results in decreased expression of ITPR2 mRNA CTD PMID:26079696 calcium atom multiple interactions ISO RGD:737250 6480464 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] more ... CTD PMID:15201137 calcium(0) multiple interactions ISO RGD:737250 6480464 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] more ... CTD PMID:15201137 carbamazepine affects expression ISO RGD:734228 6480464 Carbamazepine affects the expression of ITPR2 mRNA CTD PMID:25979313 carbon nanotube decreases expression ISO RGD:737250 6480464 Nanotubes, Carbon analog results in decreased expression of ITPR2 mRNA, Nanotubes, Carbon results in decreased expression of ITPR2 mRNA CTD PMID:25554681 chromium(6+) decreases expression ISO RGD:734228 6480464 chromium hexavalent ion results in decreased expression of ITPR2 mRNA CTD PMID:30690063 chrysene increases expression ISO RGD:737250 6480464 chrysene results in increased expression of ITPR2 mRNA CTD PMID:26377693 cisplatin multiple interactions ISO RGD:734228 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of ITPR2 mRNA CTD PMID:27392435 cisplatin decreases expression ISO RGD:734228 6480464 Cisplatin results in decreased expression of ITPR2 mRNA CTD PMID:27392435 , PMID:27594783 cobalt dichloride decreases expression ISO RGD:734228 6480464 cobaltous chloride results in decreased expression of ITPR2 mRNA CTD PMID:19320972 copper(II) sulfate decreases expression ISO RGD:734228 6480464 Copper Sulfate results in decreased expression of ITPR2 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:734228 6480464 Cyclosporine results in decreased expression of ITPR2 mRNA CTD PMID:20106945 , PMID:25562108 diarsenic trioxide multiple interactions ISO RGD:737250 6480464 Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ITPR2 mRNA] CTD PMID:29095437 diarsenic trioxide decreases expression ISO RGD:737250 6480464 Arsenic Trioxide results in decreased expression of ITPR2 mRNA CTD PMID:29095437 diarsenic trioxide increases expression ISO RGD:734228 6480464 Arsenic Trioxide results in increased expression of ITPR2 protein CTD PMID:30093655 diazinon increases methylation ISO RGD:734228 6480464 Diazinon results in increased methylation of ITPR2 gene CTD PMID:22964155 dorsomorphin multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 ethanol increases expression ISO RGD:737250 6480464 Ethanol results in increased expression of ITPR2 mRNA CTD PMID:30319688 ethanol affects splicing ISO RGD:737250 6480464 Ethanol affects the splicing of ITPR2 mRNA CTD PMID:30319688 formaldehyde decreases expression ISO RGD:734228 6480464 Formaldehyde results in decreased expression of ITPR2 mRNA CTD PMID:23649840 lead(0) increases expression EXP 6480464 Lead results in increased expression of ITPR2 mRNA, Lead results in increased expression of ITPR2 protein CTD PMID:25921245 lead(2+) increases expression EXP 6480464 Lead results in increased expression of ITPR2 mRNA, Lead results in increased expression of ITPR2 protein CTD PMID:25921245 mercury dibromide increases expression ISO RGD:734228 6480464 mercuric bromide results in increased expression of ITPR2 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITPR2 mRNA CTD PMID:27188386 metformin multiple interactions ISO RGD:737250 6480464 Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of ITPR2 mRNA] CTD PMID:29095437 methamphetamine increases expression ISO RGD:737250 6480464 Methamphetamine results in increased expression of ITPR2 mRNA CTD PMID:26307267 methapyrilene decreases methylation ISO RGD:734228 6480464 Methapyrilene results in decreased methylation of ITPR2 intron CTD PMID:30157460 methyl methanesulfonate decreases expression ISO RGD:734228 6480464 Methyl Methanesulfonate results in decreased expression of ITPR2 mRNA CTD PMID:23649840 N-hexadecanoylsphingosine increases expression ISO RGD:737250 6480464 N-palmitoylsphingosine results in increased expression of ITPR2 mRNA CTD PMID:28223344 N-hexadecanoylsphingosine multiple interactions ISO RGD:737250 6480464 [N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of ITPR2 mRNA more ... CTD PMID:28223344 ozone decreases expression ISO RGD:737250 6480464 Ozone results in decreased expression of ITPR2 mRNA CTD PMID:12763052 panobinostat multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITPR2 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:734228 6480464 panobinostat results in increased expression of ITPR2 mRNA CTD PMID:26272509 paracetamol affects expression ISO RGD:737250 6480464 Acetaminophen affects the expression of ITPR2 mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:734228 6480464 Acetaminophen results in decreased expression of ITPR2 mRNA CTD PMID:21420995 pentanal decreases expression ISO RGD:734228 6480464 pentanal results in decreased expression of ITPR2 mRNA CTD PMID:26079696 phenethyl caffeate multiple interactions ISO RGD:737250 6480464 [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA, NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA] CTD PMID:28223344 phenylephrine increases activity ISO RGD:737250 6480464 Phenylephrine results in increased activity of ITPR2 protein CTD PMID:15201137 phenylephrine multiple interactions ISO RGD:737250 6480464 [Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of ACTA1 mRNA, [Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of NPPA mRNA CTD PMID:15201137 phenylmercury acetate increases expression ISO RGD:734228 6480464 Phenylmercuric Acetate results in increased expression of ITPR2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITPR2 mRNA CTD PMID:27188386 potassium chromate multiple interactions ISO RGD:734228 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ITPR2 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:734228 6480464 potassium chromate(VI) results in decreased expression of ITPR2 mRNA CTD PMID:22079256 , PMID:22714537 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of ITPR2 mRNA CTD PMID:19423681 quercetin decreases expression ISO RGD:734228 6480464 Quercetin results in decreased expression of ITPR2 mRNA CTD PMID:21632981 rac-lactic acid increases expression ISO RGD:734228 6480464 Lactic Acid results in increased expression of ITPR2 mRNA CTD PMID:30851411 SB 431542 multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sodium arsenite decreases expression ISO RGD:734228 6480464 sodium arsenite results in decreased expression of ITPR2 mRNA CTD PMID:29301061 sodium dichromate decreases expression ISO RGD:734228 6480464 sodium bichromate results in decreased expression of ITPR2 mRNA CTD PMID:17685462 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of ITPR2 mRNA CTD PMID:25993096 sodium fluoride increases expression ISO RGD:737250 6480464 Sodium Fluoride results in increased expression of ITPR2 protein CTD PMID:28918527 succimer multiple interactions ISO RGD:737250 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ITPR2 mRNA CTD PMID:26378955 tamibarotene affects expression ISO RGD:734228 6480464 tamibarotene affects the expression of ITPR2 mRNA CTD PMID:15498508 tauroursodeoxycholic acid multiple interactions ISO RGD:737250 6480464 tauroursodeoxycholic acid inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of ITPR2 mRNA], tauroursodeoxycholic acid inhibits the reaction [N-palmitoylsphingosine results in increased expression of ITPR2 mRNA] CTD PMID:28223344 thapsigargin increases expression ISO RGD:737250 6480464 Thapsigargin results in increased expression of ITPR2 mRNA CTD PMID:28223344 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ITPR2 mRNA CTD PMID:23411599 torcetrapib increases expression ISO RGD:734228 6480464 torcetrapib results in increased expression of ITPR2 mRNA CTD PMID:23228038 trichostatin A increases expression ISO RGD:734228 6480464 trichostatin A results in increased expression of ITPR2 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITPR2 mRNA CTD PMID:27188386 triclosan increases expression ISO RGD:734228 6480464 Triclosan results in increased expression of ITPR2 mRNA CTD PMID:30510588 tungsten decreases expression ISO RGD:737250 6480464 Tungsten results in decreased expression of ITPR2 mRNA CTD PMID:30912803 valproic acid decreases expression ISO RGD:734228 6480464 Valproic Acid results in decreased expression of ITPR2 mRNA CTD PMID:29154799 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of ITPR2 mRNA CTD PMID:29427782 valproic acid multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITPR2 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:734228 6480464 Valproic Acid results in increased expression of ITPR2 mRNA CTD PMID:23179753 more ... valproic acid decreases methylation ISO RGD:734228 6480464 Valproic Acid results in decreased methylation of ITPR2 gene CTD PMID:29154799 vancomycin increases expression ISO RGD:737250 6480464 Vancomycin results in increased expression of ITPR2 mRNA CTD PMID:18930951 vorinostat multiple interactions ISO RGD:734228 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITPR2 mRNA CTD PMID:27188386 xestospongin C multiple interactions ISO RGD:737250 6480464 xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] CTD PMID:15201137
Gene-Chemical Interaction Annotations
