Gene: Itpr2 (inositol 1,4,5-trisphosphate receptor, type 2) Rattus norvegicus
Symbol: Itpr2
Name: inositol 1,4,5-trisphosphate receptor, type 2
Description: ENCODES a protein that exhibits calcium ion binding; inositol 1,4,5 trisphosphate binding; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; INVOLVED IN cellular response to hypoxia; release of sequestered calcium ion into cytosol; calcium ion transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH ANHIDROSIS, FAMILIAL GENERALIZED, WITH ABNORMAL OR ABSENT SWEAT GLANDS (ortholog); amyotrophic lateral sclerosis (ortholog); ANHIDROSIS, ISOLATED, WITH NORMAL SWEAT GLANDS (ortholog); FOUND IN axon; cytoplasm; endoplasmic reticulum; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 2,6-dinitrotoluene; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: inositol 1,4,5-triphosphate receptor 2; inositol 1,4,5-triphosphate receptor type 2; inositol 1,4,5-triphosphate receptor, type 2; inositol 1,4,5-trisphosphate receptor type 2; inositol 145-triphosphate receptor type 2; inositol triphosphate receptor type 2; insP3R2; IP3 receptor; IP3R 2; type 2 inositol 1,4,5-trisphosphate receptor; type 2 InsP3 receptor
Homo sapiens (human) : ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)  HGNC  Alliance
Mus musculus (house mouse) : Itpr2 (inositol 1,4,5-triphosphate receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itpr2 (inositol 1,4,5-trisphosphate receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
Canis lupus familiaris (dog) : ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itpr2 (inositol 1,4,5-trisphosphate receptor type 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04180,423,452 - 180,800,088 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04244,585,711 - 244,960,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44183,677,606 - 184,066,130 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14183,922,730 - 184,311,254 (-)NCBI
Celera4167,526,971 - 167,901,481 (-)NCBICelera
Cytogenetic Map4q44NCBI
RH 3.4 Map41070.3RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Itpr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69649
Created: 2001-12-06
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE