Gfra4 (GDNF family receptor alpha 4) - Rat Genome Database

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Gene: Gfra4 (GDNF family receptor alpha 4) Rattus norvegicus
Analyze
Symbol: Gfra4
Name: GDNF family receptor alpha 4
RGD ID: 620503
Description: Enables glial cell-derived neurotrophic factor receptor activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within negative regulation of ossification. Located in extracellular space. Orthologous to human GFRA4 (GDNF family receptor alpha 4); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR-alpha-4; glial cell line derived neurotrophic factor family receptor alpha 4; neurotrophic factor receptor splice variant A (Gfra4 gene); persephin receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,254,937 - 118,262,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,255,402 - 118,258,329 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,149,255 - 122,152,241 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03130,747,254 - 130,750,240 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03128,405,366 - 128,408,352 (-)NCBIRnor_WKY
Rnor_6.03123,573,394 - 123,582,431 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,578,997 - 123,581,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,077,877 - 130,081,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,712,252 - 118,714,773 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,617,824 - 118,620,346 (-)NCBI
Celera3117,065,274 - 117,067,795 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin. Masure S, etal., J Biol Chem 2000 Dec 15;275(50):39427-34.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16497798   PMID:23376485  


Genomics

Comparative Map Data
Gfra4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,254,937 - 118,262,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,255,402 - 118,258,329 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,149,255 - 122,152,241 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03130,747,254 - 130,750,240 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03128,405,366 - 128,408,352 (-)NCBIRnor_WKY
Rnor_6.03123,573,394 - 123,582,431 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,578,997 - 123,581,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,077,877 - 130,081,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,712,252 - 118,714,773 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,617,824 - 118,620,346 (-)NCBI
Celera3117,065,274 - 117,067,795 (-)NCBICelera
Cytogenetic Map3q36NCBI
GFRA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,659,248 - 3,663,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl203,659,248 - 3,663,399 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,639,895 - 3,644,046 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,587,939 - 3,592,046 (-)NCBINCBI36Build 36hg18NCBI36
Build 34203,587,938 - 3,592,046NCBI
Celera203,701,823 - 3,705,927 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,588,274 - 3,592,378 (-)NCBIHuRef
CHM1_1203,640,254 - 3,644,358 (-)NCBICHM1_1
T2T-CHM13v2.0203,690,188 - 3,694,336 (-)NCBIT2T-CHM13v2.0
Gfra4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,881,552 - 130,885,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,881,552 - 130,885,008 (-)EnsemblGRCm39 Ensembl
GRCm382131,039,632 - 131,043,088 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,039,632 - 131,043,088 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,865,912 - 130,868,824 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,731,617 - 130,734,123 (-)NCBIMGSCv36mm8
Celera2132,264,900 - 132,267,812 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
Gfra4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541514,513,183 - 14,514,140 (-)NCBIChiLan1.0ChiLan1.0
GFRA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1203,499,690 - 3,503,081 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0203,740,538 - 3,745,601 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GFRA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,685,888 - 17,690,747 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,686,817 - 17,690,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,515,732 - 17,520,613 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,104,690 - 18,109,573 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,105,641 - 18,109,587 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,699,436 - 17,704,303 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,811,187 - 17,816,066 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,138,277 - 18,143,160 (+)NCBIUU_Cfam_GSD_1.0
Gfra4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,703,881 - 166,708,001 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,135,245 - 15,139,000 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648515,135,245 - 15,139,639 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFRA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,040,235 - 32,046,105 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,040,183 - 32,044,396 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,367,615 - 36,372,394 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GFRA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607110,096,841 - 10,106,162 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfra4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,753,792 - 4,757,642 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,752,376 - 4,757,642 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gfra4
14 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:48
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000047947
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat

Markers in Region
RH137976  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,255,036 - 118,255,227 (+)MAPPERmRatBN7.2
Rnor_6.03123,578,632 - 123,578,822NCBIRnor6.0
Rnor_5.03130,077,977 - 130,078,167UniSTSRnor5.0
RGSC_v3.43118,711,887 - 118,712,077UniSTSRGSC3.4
Celera3117,064,909 - 117,065,099UniSTS
RH 3.4 Map31013.0UniSTS
Cytogenetic Map3q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 3 11
Low 2 41 14 4 4 4 5 8 61 35 29 10 5
Below cutoff 2 31 28 11 28 3 3 10 1 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001837048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ294475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ294476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000047947   ⟹   ENSRNOP00000042875
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,255,402 - 118,257,923 (-)Ensembl
Rnor_6.0 Ensembl3123,578,997 - 123,581,518 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104014   ⟹   ENSRNOP00000095734
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,255,402 - 118,258,329 (-)Ensembl
RefSeq Acc Id: NM_023967   ⟹   NP_076457
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,255,402 - 118,257,923 (-)NCBI
Rnor_6.03123,578,997 - 123,581,518 (-)NCBI
Rnor_5.03130,077,877 - 130,081,784 (-)NCBI
RGSC_v3.43118,712,252 - 118,714,773 (-)RGD
Celera3117,065,274 - 117,067,795 (-)RGD
Sequence:
RefSeq Acc Id: XM_006235041   ⟹   XP_006235103
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,254,937 - 118,262,252 (-)NCBI
Rnor_6.03123,575,803 - 123,582,431 (-)NCBI
Rnor_5.03130,077,877 - 130,081,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235042   ⟹   XP_006235104
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,254,937 - 118,262,252 (-)NCBI
Rnor_6.03123,578,992 - 123,582,431 (-)NCBI
Rnor_5.03130,077,877 - 130,081,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235043   ⟹   XP_006235105
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,254,937 - 118,262,252 (-)NCBI
Rnor_6.03123,575,803 - 123,582,431 (-)NCBI
Rnor_5.03130,077,877 - 130,081,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235045   ⟹   XP_006235107
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,254,937 - 118,262,252 (-)NCBI
Rnor_6.03123,578,992 - 123,582,431 (-)NCBI
Rnor_5.03130,077,877 - 130,081,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762197   ⟹   XP_008760419
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23118,254,937 - 118,262,252 (-)NCBI
Rnor_6.03123,575,803 - 123,582,431 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_076457   ⟸   NM_023967
- Peptide Label: precursor
- UniProtKB: Q9EPI2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006235105   ⟸   XM_006235043
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006235103   ⟸   XM_006235041
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006235107   ⟸   XM_006235045
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006235104   ⟸   XM_006235042
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008760419   ⟸   XM_008762197
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000042875   ⟸   ENSRNOT00000047947
RefSeq Acc Id: ENSRNOP00000095734   ⟸   ENSRNOT00000104014
Protein Domains
GDNF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPI2-F1-model_v2 AlphaFold Q9EPI2 1-273 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620503 AgrOrtholog
BioCyc Gene G2FUF-47832 BioCyc
Ensembl Genes ENSRNOG00000021241 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042875 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000095734 ENTREZGENE
  ENSRNOP00000095734.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047947 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000104014 ENTREZGENE
  ENSRNOT00000104014.1 UniProtKB/TrEMBL
InterPro GDNF/GAS1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDNF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDNF_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:66023 UniProtKB/Swiss-Prot
NCBI Gene 66023 ENTREZGENE
PANTHER PTHR10269 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GDNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gfra4 PhenoGen
PRINTS GDNFRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GDNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF110035 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AS10_RAT UniProtKB/TrEMBL
  GFRA4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q9EPI3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Gfra4  GDNF family receptor alpha 4  Gfra4  glial cell line derived neurotrophic factor family receptor alpha 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Gfra4  glial cell line derived neurotrophic factor family receptor alpha 4    neurotrophic factor receptor splice variant A (Gfra4 gene)  Name updated 1299863 APPROVED
2002-08-07 Gfra4  neurotrophic factor receptor splice variant A (Gfra4 gene)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression present in cortex, hippocampus, cerebellum, substantia nigra, olfactory bulb, and facial nucleus 727298