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Gene: Smpd4 (sphingomyelin phosphodiesterase 4) Rattus norvegicus
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Symbol: Smpd4
Name: sphingomyelin phosphodiesterase 4
Description: Predicted to have sphingomyelin phosphodiesterase D activity. Predicted to be involved in cellular response to tumor necrosis factor; ceramide biosynthetic process; and phospholipid catabolic process. Predicted to localize to the endoplasmic reticulum and trans-Golgi network. Orthologous to human SMPD4 (sphingomyelin phosphodiesterase 4); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC303790; RGD1310674; similar to RIKEN cDNA 4122402O22; sphingomyelin phosphodiesterase 4, neutral membrane
Orthologs:
Homo sapiens (human) : SMPD4 (sphingomyelin phosphodiesterase 4)  HGNC  Alliance
Mus musculus (house mouse) : Smpd4 (sphingomyelin phosphodiesterase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smpd4 (sphingomyelin phosphodiesterase 4)
Canis lupus familiaris (dog) : SMPD4 (sphingomyelin phosphodiesterase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smpd4 (sphingomyelin phosphodiesterase 4)
Sus scrofa (pig) : SMPD4 (sphingomyelin phosphodiesterase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01187,522,971 - 87,546,687 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01190,575,599 - 90,599,309 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,352,180 - 85,375,918 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15169,511,693 - 169,512,094 (+)NCBI
Celera1182,134,192 - 82,157,831 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Smpd4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310674
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.