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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Theaflavin 3,3'-digallate
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Accession:CHEBI:136608 term browser browse the term
Synonyms:exact_synonym: (3,4,5-Trihydroxy-6-oxo-6H-benzo[7]annulene-1,8-diyl)bis[(2R,3R)-5,7-dihydroxy-3,4-dihydro-2H-chromene-2,3-diyl] bis(3,4,5-trihydroxybenzoate)
 related_synonym: Formula=C43H32O20;   InChI=1S/C43H32O20/c44-17-7-23(46)21-12-33(62-42(58)15-3-25(48)36(54)26(49)4-15)40(60-31(21)9-17)14-1-19-20(11-30(53)39(57)35(19)38(56)29(52)2-14)41-34(13-22-24(47)8-18(45)10-32(22)61-41)63-43(59)16-5-27(50)37(55)28(51)6-16/h1-11,33-34,40-41,44-51,53-55,57H,12-13H2,(H,52,56)/t33-,34-,40-,41-/m1/s1;   InChIKey=ZEASWHWETFMWCV-ISBUVJFSSA-N;   SMILES=O1[C@@H]([C@H](OC(=O)C2=CC(O)=C(O)C(O)=C2)CC=3C1=CC(O)=CC3O)C=4C5=CC([C@H]6OC=7C(C[C@H]6OC(=O)C8=CC(O)=C(O)C(O)=C8)=C(O)C=C(O)C7)=CC(=O)C(O)=C5C(O)=C(O)C4
 xref: Chemspider:410681
 xref_mesh: MESH:C585473


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Theaflavin 3,3'-digallate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ABCC2 mRNA CTD PMID:34925699 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA] CTD PMID:36105184 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acan aggrecan multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN protein] CTD PMID:35847580 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Accsl 1-aminocyclopropane-1-carboxylate synthase-like affects expression ISO theaflavin-3,3'-digallate affects the expression of ACCSL mRNA CTD PMID:34925699 NCBI chr 3:79,826,464...79,841,163
Ensembl chr 3:79,826,464...79,841,163 		JBrowse link
G Ace2 angiotensin converting enzyme 2 affects binding ISO theaflavin-3,3'-digallate binds to ACE2 protein CTD PMID:34138966 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Galactose results in increased activity of ACHE protein] CTD PMID:36638877 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acot6 acyl-CoA thioesterase 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of ACOT6 mRNA CTD PMID:34925699 NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446 		JBrowse link
G Acrbp acrosin binding protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ACRBP mRNA CTD PMID:34925699 NCBI chr 4:157,851,149...157,864,211
Ensembl chr 4:157,841,841...157,864,213 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of ACTA2 protein] CTD PMID:35903325 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actl6b actin-like 6B affects expression ISO theaflavin-3,3'-digallate affects the expression of ACTL6B mRNA CTD PMID:34925699 NCBI chr12:19,124,887...19,141,419
Ensembl chr12:19,124,916...19,141,376 		JBrowse link
G Adam30 ADAM metallopeptidase domain 30 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADAM30 mRNA CTD PMID:34925699 NCBI chr 2:185,752,183...185,755,623
Ensembl chr 2:185,752,072...185,755,599 		JBrowse link
G Adam32 ADAM metallopeptidase domain 32 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADAM32 mRNA CTD PMID:34925699 NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161 		JBrowse link
G Adam33 ADAM metallopeptidase domain 33 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADAM33 mRNA CTD PMID:34925699 NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein] CTD PMID:35847580 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Add2 adducin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADD2 mRNA CTD PMID:34925699 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505 		JBrowse link
G Adgrf2 adhesion G protein-coupled receptor F2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADGRF2 mRNA CTD PMID:34925699 NCBI chr 9:18,238,389...18,248,745
Ensembl chr 9:18,219,714...18,269,038 		JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 affects expression ISO theaflavin-3,3'-digallate affects the expression of ADGRG7 mRNA CTD PMID:34925699 NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Methylmercury Compounds results in increased secretion of ADIPOQ protein] CTD PMID:31195622 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adra2b adrenoceptor alpha 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of ADRA2B mRNA CTD PMID:34925699 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ADTRP mRNA CTD PMID:34925699 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Agt angiotensinogen multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased abundance of Nitric Oxide]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased activity of CAT protein]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased phosphorylation of NFATC3 protein]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of ANP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of BNP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of PPP3CA protein] CTD PMID:35406003 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [Tetrachlorodibenzodioxin binds to and affects the activity of AHR protein] CTD PMID:15914905 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of AIPL1 mRNA CTD PMID:34925699 NCBI chr10:56,655,693...56,664,922
Ensembl chr10:56,655,693...56,664,922 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO		 theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of AKT1 protein]
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:12931129 PMID:35847580 PMID:35903325 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Allc allantoicase affects expression ISO theaflavin-3,3'-digallate affects the expression of ALLC mRNA CTD PMID:34925699 NCBI chr 6:45,179,181...45,214,275
Ensembl chr 6:45,179,187...45,214,223 		JBrowse link
G Alpg alkaline phosphatase, germ cell affects expression ISO theaflavin-3,3'-digallate affects the expression of ALPPL2 mRNA CTD PMID:34925699 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836 		JBrowse link
G Amh anti-Mullerian hormone increases expression ISO theaflavin-3,3'-digallate results in increased expression of AMH mRNA CTD PMID:34925699 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of AMPD1 mRNA CTD PMID:34925699 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938 		JBrowse link
G Amz1 archaelysin family metallopeptidase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of AMZ1 mRNA CTD PMID:34925699 NCBI chr12:13,886,518...13,924,275
Ensembl chr12:13,891,123...13,909,783 		JBrowse link
G Ang angiogenin decreases secretion
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased secretion of ANG protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased secretion of ANG protein		 CTD PMID:34350509 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Ankub1 ankyrin repeat and ubiquitin domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ANKUB1 mRNA CTD PMID:34925699 NCBI chr 2:141,857,623...141,894,624
Ensembl chr 2:141,856,573...141,894,339 		JBrowse link
G Apoa4 apolipoprotein A4 affects expression ISO theaflavin-3,3'-digallate affects the expression of APOA4 mRNA CTD PMID:34925699 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apol9a apolipoprotein L9a affects expression ISO theaflavin-3,3'-digallate affects the expression of APOL4 mRNA CTD PMID:34925699 NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression ISO theaflavin-3,3'-digallate affects the expression of ARC mRNA CTD PMID:34925699 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Areg amphiregulin affects expression ISO theaflavin-3,3'-digallate affects the expression of AREG mRNA CTD PMID:34925699 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Asb15 ankyrin repeat and SOCS box containing 15 affects expression ISO theaflavin-3,3'-digallate affects the expression of ASB15 mRNA CTD PMID:34925699 NCBI chr 4:53,021,553...53,050,846
Ensembl chr 4:53,031,692...53,049,928 		JBrowse link
G Asic4 acid sensing ion channel subunit family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of ASIC4 mRNA CTD PMID:34925699 NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900 		JBrowse link
G Atoh1 atonal bHLH transcription factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATOH1 mRNA CTD PMID:34925699 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154 		JBrowse link
G Atp10b ATPase phospholipid transporting 10B affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP10B mRNA CTD PMID:34925699 NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637 		JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP1A4 mRNA CTD PMID:34925699 NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687 		JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP1B4 mRNA CTD PMID:34925699 NCBI chr  X:117,087,284...117,108,023
Ensembl chr  X:117,057,423...117,108,020 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP2A1 mRNA CTD PMID:34925699 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ATP2B2 mRNA CTD PMID:34925699 NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Avil advillin affects expression ISO theaflavin-3,3'-digallate affects the expression of AVIL mRNA CTD PMID:34925699 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression ISO theaflavin-3,3'-digallate affects the expression of BAAT mRNA CTD PMID:34925699 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
decreases expression
multiple interactions		 ISO
EXP		 theaflavin-3,3'-digallate results in increased expression of BAX protein
theaflavin-3,3'-digallate results in decreased expression of BAX mRNA; theaflavin-3,3'-digallate results in decreased expression of BAX protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of BAX protein		 CTD PMID:30769778 PMID:32964953 PMID:34350509 PMID:34925699 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
multiple interactions		 EXP
ISO		 theaflavin-3,3'-digallate results in increased expression of BCL2 mRNA; theaflavin-3,3'-digallate results in increased expression of BCL2 protein
theaflavin-3,3'-digallate results in decreased expression of BCL2 protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of BCL2 protein		 CTD PMID:32964953 PMID:34350509 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of BCL2L1 protein CTD PMID:30769778 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Becn1 beclin 1 decreases expression
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased expression of BECN1 protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of BECN1 protein		 CTD PMID:34350509 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of BGLAP protein]; theaflavin-3,3'-digallate results in increased expression of and results in increased secretion of BGLAP protein CTD PMID:33833684 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bmp15 bone morphogenetic protein 15 increases expression ISO theaflavin-3,3'-digallate results in increased expression of BMP15 mRNA CTD PMID:34925699 NCBI chr  X:16,169,123...16,174,187
Ensembl chr  X:16,169,123...16,174,187 		JBrowse link
G Bnc1 basonuclin zinc finger protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of BNC1 mRNA CTD PMID:34925699 NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333 		JBrowse link
G Bnipl BCL2 interacting protein like affects expression ISO theaflavin-3,3'-digallate affects the expression of BNIPL mRNA CTD PMID:34925699 NCBI chr 2:182,818,593...182,830,421
Ensembl chr 2:182,818,595...182,828,588 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor affects expression ISO theaflavin-3,3'-digallate affects the expression of BOP1 mRNA CTD PMID:34925699 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931 		JBrowse link
G Btla B and T lymphocyte associated affects expression ISO theaflavin-3,3'-digallate affects the expression of BTLA mRNA CTD PMID:34925699 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181 		JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 affects expression ISO theaflavin-3,3'-digallate affects the expression of BTN1A1 mRNA CTD PMID:34925699 NCBI chr17:41,653,499...41,664,246
Ensembl chr17:41,654,249...41,664,272 		JBrowse link
G Bysl bystin-like affects expression ISO theaflavin-3,3'-digallate affects the expression of BYSL mRNA CTD PMID:34925699 NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339 		JBrowse link
G C13h1orf116 similar to human chromosome 1 open reading frame 116 affects expression ISO theaflavin-3,3'-digallate affects the expression of C1ORF116 mRNA CTD PMID:34925699 NCBI chr13:42,187,442...42,201,432
Ensembl chr13:42,188,609...42,201,426 		JBrowse link
G C14h4orf19 similar to human chromosome 4 open reading frame 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of C4ORF19 mRNA CTD PMID:34925699 NCBI chr14:44,387,386...44,478,344
Ensembl chr14:44,387,393...44,478,041 		JBrowse link
G C1qtnf2 C1q and TNF related 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of C1QTNF2 mRNA CTD PMID:34925699 NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185 		JBrowse link
G C4h3orf20 similar to human chromosome 3 open reading frame 20 affects expression ISO theaflavin-3,3'-digallate affects the expression of C3ORF20 mRNA CTD PMID:34925699 NCBI chr 4:124,422,033...124,470,657
Ensembl chr 4:124,432,193...124,469,254 		JBrowse link
G C5ar2 complement C5a receptor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of C5AR2 mRNA CTD PMID:34925699 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517 		JBrowse link
G C5h9orf152 similar to human chromosome 9 open reading frame 152 affects expression ISO theaflavin-3,3'-digallate affects the expression of C9ORF152 mRNA CTD PMID:34925699 NCBI chr 5:72,660,573...72,667,941
Ensembl chr 5:72,660,573...72,668,379 		JBrowse link
G C7h12orf50 similar to human chromosome 12 open reading frame 50 affects expression ISO theaflavin-3,3'-digallate affects the expression of C12ORF50 mRNA CTD PMID:34925699 NCBI chr 7:35,406,147...35,443,324
Ensembl chr 7:35,411,555...35,443,320 		JBrowse link
G C9 complement C9 affects expression ISO theaflavin-3,3'-digallate affects the expression of C9 mRNA CTD PMID:34925699 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338 		JBrowse link
G Capn11 calpain 11 affects expression ISO theaflavin-3,3'-digallate affects the expression of CAPN11 mRNA CTD PMID:34925699 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601 		JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions
increases activity		 ISO
EXP		 theaflavin-3,3'-digallate results in decreased expression of CASP3 protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of and results in increased cleavage of and results in increased activity of CASP3 protein; theaflavin-3,3'-digallate results in increased expression of and results in increased cleavage of and results in increased activity of CASP3 protein
theaflavin-3,3'-digallate results in increased activity of CASP3 protein
theaflavin-3,3'-digallate results in decreased expression of CASP3 mRNA; theaflavin-3,3'-digallate results in decreased expression of CASP3 protein		 CTD PMID:30769778 PMID:32964953 PMID:34350509 PMID:34925699 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO theaflavin-3,3'-digallate results in increased activity of CASP8 protein CTD PMID:30769778 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity		 ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein; theaflavin-3,3'-digallate results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein
theaflavin-3,3'-digallate results in increased activity of CASP9 protein		 CTD PMID:30769778 PMID:34350509 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cass4 Cas scaffold protein family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of CASS4 mRNA CTD PMID:34925699 NCBI chr 3:161,162,520...161,202,523
Ensembl chr 3:161,163,436...161,202,186 		JBrowse link
G Cat catalase multiple interactions ISO
EXP		 theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]
theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased activity of CAT protein]		 CTD PMID:32694992 PMID:35406003 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cc2d2b coiled-coil and C2 domain containing 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of CC2D2B mRNA CTD PMID:34925699 NCBI chr 1:239,561,506...239,655,771
Ensembl chr 1:239,561,987...239,682,416 		JBrowse link
G Ccdc17 coiled-coil domain containing 17 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC17 mRNA CTD PMID:34925699 NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673 		JBrowse link
G Ccdc62 coiled-coil domain containing 62 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC62 mRNA CTD PMID:34925699 NCBI chr12:32,623,170...32,659,912
Ensembl chr12:32,623,170...32,660,017 		JBrowse link
G Ccdc65 coiled-coil domain containing 65 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC65 mRNA CTD PMID:34925699 NCBI chr 7:129,857,118...129,870,803
Ensembl chr 7:129,857,247...129,870,803 		JBrowse link
G Ccdc70 coiled-coil domain containing 70 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCDC70 mRNA CTD PMID:34925699 NCBI chr16:70,037,309...70,042,401
Ensembl chr16:70,037,309...70,042,339 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCL4 mRNA CTD PMID:34925699 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased expression of CCND1 protein
CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CCND1 protein]		 CTD PMID:30769778 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCR1 mRNA CTD PMID:34925699 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr6 C-C motif chemokine receptor 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of CCR6 mRNA CTD PMID:34925699 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Cd300e Cd300e molecule affects expression ISO theaflavin-3,3'-digallate affects the expression of CD300E mRNA CTD PMID:34925699 NCBI chr10:100,289,729...100,309,996
Ensembl chr10:100,291,437...100,299,311 		JBrowse link
G Cd33 CD33 molecule affects expression ISO theaflavin-3,3'-digallate affects the expression of CD33 mRNA CTD PMID:34925699 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149 		JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex affects expression ISO theaflavin-3,3'-digallate affects the expression of CD3G mRNA CTD PMID:34925699 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CD40 mRNA] CTD PMID:32694992 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd69 Cd69 molecule affects expression ISO theaflavin-3,3'-digallate affects the expression of CD69 mRNA CTD PMID:34925699 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CDC42EP1 mRNA CTD PMID:34925699 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased expression of CDK4 protein
CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CDK4 protein]		 CTD PMID:30769778 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CDK5R1 mRNA CTD PMID:34925699 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression		 ISO CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein]; CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CCND1 protein]; CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of CDK4 protein]
theaflavin-3,3'-digallate results in increased expression of CDKN1B protein		 CTD PMID:30769778 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdx2 caudal type homeo box 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CDX2 mRNA CTD PMID:34925699 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of CEACAM4 mRNA CTD PMID:34925699 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of CEBPA mRNA CTD PMID:34925699 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cfap141 cilia and flagella associated protein 141 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP141 mRNA CTD PMID:34925699 NCBI chr 2:175,507,628...175,510,662
Ensembl chr 2:175,507,628...175,510,662 		JBrowse link
G Cfap161 cilia and flagella associated protein 161 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP161 mRNA CTD PMID:34925699 NCBI chr 1:137,743,783...137,768,685
Ensembl chr 1:137,743,784...137,768,730 		JBrowse link
G Cfap206 cilia and flagella associated protein 206 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP206 mRNA CTD PMID:34925699 NCBI chr 5:49,254,399...49,299,145
Ensembl chr 5:49,254,408...49,299,090 		JBrowse link
G Cfap276 cilia and flagella associated protein 276 affects expression ISO theaflavin-3,3'-digallate affects the expression of CFAP276 mRNA CTD PMID:34925699 NCBI chr 2:196,166,009...196,177,919
Ensembl chr 2:196,166,009...196,177,919 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHAC1 mRNA CTD PMID:34925699 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHD5 mRNA CTD PMID:34925699 NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO theaflavin-3,3'-digallate results in increased phosphorylation of CHEK2 protein CTD PMID:30769778 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of CHRM5 mRNA CTD PMID:34925699 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit affects expression ISO theaflavin-3,3'-digallate affects the expression of CHRNA3 mRNA CTD PMID:34925699 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit affects expression ISO theaflavin-3,3'-digallate affects the expression of CHRNA4 mRNA CTD PMID:34925699 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Clcn1 chloride voltage-gated channel 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CLCN1 mRNA CTD PMID:34925699 NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984 		JBrowse link
G Cldn19 claudin 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of CLDN19 mRNA CTD PMID:34925699 NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227 		JBrowse link
G Clec4a1 C-type lectin domain family 4, member A1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZNF705A mRNA CTD PMID:34925699 NCBI chr 4:156,173,894...156,186,009
Ensembl chr 4:156,173,894...156,186,008 		JBrowse link
G Clec5a C-type lectin domain containing 5A affects expression ISO theaflavin-3,3'-digallate affects the expression of CLEC5A mRNA CTD PMID:34925699 NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859 		JBrowse link
G Clec7a C-type lectin domain containing 7A affects expression ISO theaflavin-3,3'-digallate affects the expression of CLEC7A mRNA CTD PMID:34925699 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Cmtm2b CKLF-like MARVEL transmembrane domain containing 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of CMTM2 mRNA CTD PMID:34925699 NCBI chr19:640,838...651,872
Ensembl chr19:640,824...651,939 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CNBD2 mRNA CTD PMID:34925699 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583 		JBrowse link
G Cndp1 carnosine dipeptidase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CNDP1 mRNA CTD PMID:34925699 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765 		JBrowse link
G Cnr1 cannabinoid receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CNR1 mRNA CTD PMID:34925699 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col11a2 collagen type XI alpha 2 chain affects expression ISO theaflavin-3,3'-digallate affects the expression of COL11A2 mRNA CTD PMID:34925699 NCBI chr20:4,786,932...4,816,598
Ensembl chr20:4,786,929...4,815,985 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein] CTD PMID:35847580 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Cplx3 complexin 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of CPLX3 mRNA CTD PMID:34925699 NCBI chr 8:58,003,535...58,010,297
Ensembl chr 8:58,003,535...58,010,297 		JBrowse link
G Cr2 complement C3d receptor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CR2 mRNA CTD PMID:34925699 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235 		JBrowse link
G Crybb2 crystallin, beta B2 affects expression ISO theaflavin-3,3'-digallate affects the expression of CRYBB2 mRNA CTD PMID:34925699 NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of CTNNB1 protein] CTD PMID:33833684 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:32694992 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsl cathepsin L decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of CTSL protein CTD PMID:34138966 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP1A2 mRNA] CTD PMID:36105184 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP26A1 mRNA CTD PMID:34925699 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP2B6 mRNA CTD PMID:34925699 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP4B1 mRNA CTD PMID:34925699 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 affects expression
multiple interactions		 ISO theaflavin-3,3'-digallate affects the expression of CYP4F12 mRNA
theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP4F14 mRNA]		 CTD PMID:34925699 PMID:36105184 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of CYP7A1 mRNA CTD PMID:34925699 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DCAF12L1 mRNA CTD PMID:34925699 NCBI chr  X:123,695,286...123,698,905
Ensembl chr  X:123,695,286...123,698,905 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
multiple interactions		 ISO theaflavin-3,3'-digallate affects the expression of DDIT3 mRNA
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in increased expression of DDIT3 protein		 CTD PMID:34350509 PMID:34925699 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dgkb diacylglycerol kinase, beta affects expression ISO theaflavin-3,3'-digallate affects the expression of DGKB mRNA CTD PMID:34925699 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of DHCR7 mRNA] CTD PMID:36105184 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of DHRS9 mRNA CTD PMID:34925699 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of DKK4 mRNA CTD PMID:34925699 NCBI chr16:69,403,215...69,406,580
Ensembl chr16:69,402,989...69,406,580 		JBrowse link
G Dlx1 distal-less homeobox 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DLX1 mRNA CTD PMID:34925699 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780 		JBrowse link
G Dnaaf1 dynein, axonemal, assembly factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DNAAF1 mRNA CTD PMID:34925699 NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313 		JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 affects expression ISO theaflavin-3,3'-digallate affects the expression of DNAH11 mRNA CTD PMID:34925699 NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536 		JBrowse link
G Dnah12 dynein, axonemal, heavy chain 12 affects expression ISO theaflavin-3,3'-digallate affects the expression of DNAH12 mRNA CTD PMID:34925699 NCBI chr16:1,936,354...2,092,663
Ensembl chr16:1,937,817...2,092,664 		JBrowse link
G Dnase2b deoxyribonuclease 2 beta affects expression ISO theaflavin-3,3'-digallate affects the expression of DNASE2B mRNA CTD PMID:34925699 NCBI chr 2:235,470,915...235,515,211
Ensembl chr 2:235,470,919...235,486,295 		JBrowse link
G Dok2 docking protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of DOK2 mRNA CTD PMID:34925699 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402 		JBrowse link
G Dppa3 developmental pluripotency-associated 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of DPPA3 mRNA CTD PMID:34925699 NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
Ensembl chr 5:155,815,296...155,854,861 		JBrowse link
G Dppa5 developmental pluripotency associated 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of DPPA5 mRNA CTD PMID:34925699 NCBI chr 8:79,215,341...79,217,282
Ensembl chr 8:79,215,362...79,216,570
Ensembl chr 7:79,215,362...79,216,570 		JBrowse link
G Drc7 dynein regulatory complex subunit 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of DRC7 mRNA CTD PMID:34925699 NCBI chr19:9,943,452...9,961,266
Ensembl chr19:9,943,456...9,961,163 		JBrowse link
G Dscaml1 DS cell adhesion molecule-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of DSCAML1 mRNA CTD PMID:34925699 NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320 		JBrowse link
G Ebln1 endogenous Bornavirus like nucleoprotein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of EBLN1 mRNA CTD PMID:34925699 NCBI chr10:78,938,645...78,940,651 JBrowse link
G Ebp EBP, cholestenol delta-isomerase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of EBP mRNA] CTD PMID:36105184 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Edn1 endothelin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of EDN1 mRNA CTD PMID:34925699 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Efnb1 ephrin B1 affects expression ISO theaflavin-3,3'-digallate affects the expression of EFNB1 mRNA CTD PMID:34925699 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased activity of SP1 protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of EGFR protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12931129 PMID:16353237 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of EGFR protein]
theaflavin-3,3'-digallate results in increased ubiquitination of and results in increased degradation of and results in decreased expression of EGFR protein		 CTD PMID:16353237 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ELOVL1 mRNA] CTD PMID:36105184 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Epha8 Eph receptor A8 affects expression ISO theaflavin-3,3'-digallate affects the expression of EPHA8 mRNA CTD PMID:34925699 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Ermn ermin affects expression ISO theaflavin-3,3'-digallate affects the expression of ERMN mRNA CTD PMID:34925699 NCBI chr 3:42,628,160...42,633,816
Ensembl chr 3:42,626,309...42,633,744 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
decreases expression		 ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of ERN1 mRNA
theaflavin-3,3'-digallate results in decreased expression of ERN1 mRNA		 CTD PMID:34350509 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ERRFI1 mRNA CTD PMID:34925699 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Evpl envoplakin affects expression ISO theaflavin-3,3'-digallate affects the expression of EVPL mRNA CTD PMID:34925699 NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763 		JBrowse link
G Ezhip EZH inhibitory protein affects expression ISO theaflavin-3,3'-digallate affects the expression of EZHIP mRNA CTD PMID:34925699 NCBI chr  X:16,368,582...16,371,648
Ensembl chr  X:16,368,962...16,372,256 		JBrowse link
G F11 coagulation factor XI affects expression ISO theaflavin-3,3'-digallate affects the expression of F11 mRNA CTD PMID:34925699 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F13b coagulation factor XIII B chain affects expression ISO theaflavin-3,3'-digallate affects the expression of F13B mRNA CTD PMID:34925699 NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381 		JBrowse link
G F2 coagulation factor II, thrombin affects expression ISO theaflavin-3,3'-digallate affects the expression of F2 mRNA CTD PMID:34925699 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of F2RL3 mRNA CTD PMID:34925699 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472 		JBrowse link
G F3 coagulation factor III, tissue factor affects expression ISO theaflavin-3,3'-digallate affects the expression of F3 mRNA CTD PMID:34925699 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fabp12 fatty acid binding protein 12 affects expression ISO theaflavin-3,3'-digallate affects the expression of FABP12 mRNA CTD PMID:34925699 NCBI chr 2:91,539,568...91,554,999
Ensembl chr 2:91,500,539...91,554,996 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FABP4 mRNA] CTD PMID:36105184 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FADS1 mRNA] CTD PMID:36105184 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fam177b family with sequence similarity 177 member B affects expression ISO theaflavin-3,3'-digallate affects the expression of FAM177B mRNA CTD PMID:34925699 NCBI chr13:94,904,128...94,909,688 JBrowse link
G Fam180a family with sequence similarity 180, member A affects expression ISO theaflavin-3,3'-digallate affects the expression of FAM180A mRNA CTD PMID:34925699 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047 		JBrowse link
G Fam83c family with sequence similarity 83, member C affects expression ISO theaflavin-3,3'-digallate affects the expression of FAM83C mRNA CTD PMID:34925699 NCBI chr 3:144,333,736...144,339,758
Ensembl chr 3:144,332,982...144,339,802 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 ISO theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS mRNA]; theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased expression of FAS protein]
theaflavin-3,3'-digallate results in increased expression of FAS protein		 CTD PMID:12931129 PMID:30769778 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand affects expression ISO theaflavin-3,3'-digallate affects the expression of FASLG mRNA CTD PMID:34925699 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fcamr Fc alpha and mu receptor affects expression ISO theaflavin-3,3'-digallate affects the expression of FCAMR mRNA CTD PMID:34925699 NCBI chr13:42,273,891...42,288,002
Ensembl chr13:42,273,628...42,287,113 		JBrowse link
G Fcrl5 Fc receptor-like 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of FCRL5 mRNA CTD PMID:34925699 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148 		JBrowse link
G Fcrl6 Fc receptor-like 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of FCRL6 mRNA CTD PMID:34925699 NCBI chr13:85,062,709...85,072,308
Ensembl chr13:85,066,694...85,072,600 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA] CTD PMID:36105184 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of FGD2 mRNA CTD PMID:34925699 NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603 		JBrowse link
G Fgf17 fibroblast growth factor 17 affects expression ISO theaflavin-3,3'-digallate affects the expression of FGF17 mRNA CTD PMID:34925699 NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063 		JBrowse link
G Fgf18 fibroblast growth factor 18 affects expression ISO theaflavin-3,3'-digallate affects the expression of FGF18 mRNA CTD PMID:34925699 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor affects expression ISO theaflavin-3,3'-digallate affects the expression of FLI1 mRNA CTD PMID:34925699 NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433 		JBrowse link
G Fndc7 fibronectin type III domain containing 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of FNDC7 mRNA CTD PMID:34925699 NCBI chr 2:196,501,313...196,537,816
Ensembl chr 2:196,502,460...196,537,694 		JBrowse link
G Foxd3 forkhead box D3 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXD3 mRNA CTD PMID:34925699 NCBI chr 5:114,335,084...114,337,450
Ensembl chr 5:114,335,408...114,336,817 		JBrowse link
G Foxd4 forkhead box D4 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXD4 mRNA CTD PMID:34925699 NCBI chr 1:222,557,494...222,559,189
Ensembl chr 1:222,557,360...222,559,159 		JBrowse link
G Foxe3 forkhead box E3 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXE3 mRNA CTD PMID:34925699 NCBI chr 5:128,444,912...128,446,494
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Foxg1 forkhead box G1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXG1 mRNA CTD PMID:34925699 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607 		JBrowse link
G Foxl1 forkhead box L1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXL1 mRNA CTD PMID:34925699 NCBI chr19:49,197,269...49,200,682
Ensembl chr19:49,197,400...49,198,425 		JBrowse link
G Foxq1 forkhead box Q1 affects expression ISO theaflavin-3,3'-digallate affects the expression of FOXQ1 mRNA CTD PMID:34925699 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 		JBrowse link
G Frmd7 FERM domain containing 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of FRMD7 mRNA CTD PMID:34925699 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771 		JBrowse link
G Frzb frizzled-related protein affects expression ISO theaflavin-3,3'-digallate affects the expression of FRZB mRNA CTD PMID:34925699 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fscn3 fascin actin-bundling protein 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of FSCN3 mRNA CTD PMID:34925699 NCBI chr 4:57,042,797...57,052,224
Ensembl chr 4:57,042,797...57,052,404 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GABRR1 mRNA CTD PMID:34925699 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228 		JBrowse link
G Galnt14 polypeptide N-acetylgalactosaminyltransferase 14 affects expression ISO theaflavin-3,3'-digallate affects the expression of GALNT14 mRNA CTD PMID:34925699 NCBI chr 6:21,756,039...21,977,533
Ensembl chr 6:21,755,195...21,972,192 		JBrowse link
G Garin1a golgi associated RAB2 interactor 1A affects expression ISO theaflavin-3,3'-digallate affects the expression of GARIN1A mRNA CTD PMID:34925699 NCBI chr 4:57,880,019...57,890,824
Ensembl chr 4:57,880,019...57,890,820 		JBrowse link
G Garin4 golgi associated RAB2 interactor family member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of GARIN4 mRNA CTD PMID:34925699 NCBI chr13:102,742,988...102,745,168
Ensembl chr13:102,742,988...102,745,168 		JBrowse link
G Gdf9 growth differentiation factor 9 affects expression
increases expression		 ISO theaflavin-3,3'-digallate affects the expression of GDF9 mRNA
theaflavin-3,3'-digallate results in increased expression of GDF9 mRNA		 CTD PMID:34925699 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of GDPD3 mRNA CTD PMID:34925699 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor affects expression ISO theaflavin-3,3'-digallate affects the expression of GFI1B mRNA CTD PMID:34925699 NCBI chr 3:11,940,232...11,952,989
Ensembl chr 3:11,940,233...11,952,942 		JBrowse link
G Ghsr growth hormone secretagogue receptor affects expression ISO theaflavin-3,3'-digallate affects the expression of GHSR mRNA CTD PMID:34925699 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GJB1 mRNA CTD PMID:34925699 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gjd4 gap junction protein, delta 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of GJD4 mRNA CTD PMID:34925699 NCBI chr17:57,348,844...57,352,601
Ensembl chr17:57,349,877...57,352,446 		JBrowse link
G Glt1d1 glycosyltransferase 1 domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GLT1D1 mRNA CTD PMID:34925699 NCBI chr12:28,975,984...29,049,707
Ensembl chr12:28,975,988...29,049,695 		JBrowse link
G Gnat1 G protein subunit alpha transducin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GNAT1 mRNA CTD PMID:34925699 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671 		JBrowse link
G Gp5 glycoprotein V (platelet) affects expression ISO theaflavin-3,3'-digallate affects the expression of GP5 mRNA CTD PMID:34925699 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPBAR1 mRNA CTD PMID:34925699 NCBI chr 9:75,860,758...75,863,260
Ensembl chr 9:75,860,677...75,863,168 		JBrowse link
G Gpr162 G protein-coupled receptor 162 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR162 mRNA CTD PMID:34925699 NCBI chr 4:157,662,200...157,668,341
Ensembl chr 4:157,662,200...157,668,121 		JBrowse link
G Gpr19 G protein-coupled receptor 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR19 mRNA CTD PMID:34925699 NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036 		JBrowse link
G Gpr25 G protein-coupled receptor 25 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR25 mRNA CTD PMID:34925699 NCBI chr13:47,712,815...47,714,721
Ensembl chr13:47,713,592...47,714,671 		JBrowse link
G Gpr82 G protein-coupled receptor 82 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR82 mRNA CTD PMID:34925699 NCBI chr  X:9,079,016...9,084,696
Ensembl chr  X:9,080,254...9,081,240 		JBrowse link
G Gpr83 G protein-coupled receptor 83 affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR83 mRNA CTD PMID:34925699 NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028 		JBrowse link
G Gpr89b G protein-coupled receptor 89B affects expression ISO theaflavin-3,3'-digallate affects the expression of GPR89B mRNA CTD PMID:34925699 NCBI chr 2:184,408,136...184,445,560
Ensembl chr 2:184,401,438...184,445,584 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of GPX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of GPX1 mRNA] CTD PMID:32694992 PMID:36638877 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of GRIA2 mRNA CTD PMID:34925699 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gsdmc gasdermin C affects expression ISO theaflavin-3,3'-digallate affects the expression of GSDMC mRNA CTD PMID:34925699 NCBI chr 7:95,594,015...95,606,106
Ensembl chr 7:95,594,015...95,611,344 		JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) affects expression ISO theaflavin-3,3'-digallate affects the expression of GTPBP6 mRNA CTD PMID:34925699 NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873 		JBrowse link
G Gucy2c guanylate cyclase 2C affects expression ISO theaflavin-3,3'-digallate affects the expression of GUCY2C mRNA CTD PMID:34925699 NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092 		JBrowse link
G H1f8 H1.8 linker histone affects expression ISO theaflavin-3,3'-digallate affects the expression of H1FOO mRNA CTD PMID:34925699 NCBI chr 4:148,993,133...148,998,254
Ensembl chr 4:148,993,133...148,998,254 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of H2AX protein CTD PMID:34925699 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HAND1 mRNA CTD PMID:34925699 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HERPUD1 mRNA CTD PMID:34925699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HES1 mRNA CTD PMID:34925699 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HEY1 mRNA CTD PMID:34925699 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression ISO theaflavin-3,3'-digallate affects the expression of HGD mRNA CTD PMID:34925699 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Hhatl hedgehog acyltransferase-like affects expression ISO theaflavin-3,3'-digallate affects the expression of HHATL mRNA CTD PMID:34925699 NCBI chr 8:121,447,001...121,454,070
Ensembl chr 8:121,447,002...121,454,001 		JBrowse link
G Hhipl2 HHIP like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of HHIPL2 mRNA CTD PMID:34925699 NCBI chr13:95,054,685...95,074,609
Ensembl chr13:95,054,694...95,074,608 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased expression of HIF1A protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HIF1A protein		 CTD PMID:34350509 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO
EXP		 theaflavin-3,3'-digallate results in increased expression of HMOX1 protein
theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 mRNA]		 CTD PMID:32694992 PMID:35847580 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hmx1 H6 family homeobox 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HMX1 mRNA CTD PMID:34925699 NCBI chr14:75,361,207...75,364,993
Ensembl chr14:75,361,225...75,364,993 		JBrowse link
G Hormad1 HORMA domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of HORMAD1 mRNA CTD PMID:34925699 NCBI chr 2:183,115,815...183,152,383
Ensembl chr 2:183,116,716...183,152,383 		JBrowse link
G Hormad2 HORMA domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of HORMAD2 mRNA CTD PMID:34925699 NCBI chr14:79,215,013...79,300,447
Ensembl chr14:79,214,998...79,299,910 		JBrowse link
G Hoxa10 homeobox A10 affects expression ISO theaflavin-3,3'-digallate affects the expression of HOXA10 mRNA CTD PMID:34925699 NCBI chr 4:81,331,591...81,340,878
Ensembl chr 4:81,331,591...81,340,919 		JBrowse link
G Hoxc10 homeo box C10 affects expression ISO theaflavin-3,3'-digallate affects the expression of HOXC10 mRNA CTD PMID:34925699 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966 		JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of HS3ST5 mRNA CTD PMID:34925699 NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased expression of HSPA1A protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HSPA1A protein		 CTD PMID:34350509 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases expression		 ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of HSPA5 protein
theaflavin-3,3'-digallate results in decreased expression of HSPA5 protein		 CTD PMID:34350509 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression ISO theaflavin-3,3'-digallate affects the expression of HSPA8 mRNA CTD PMID:34925699 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D affects expression ISO theaflavin-3,3'-digallate affects the expression of HTR1D mRNA CTD PMID:34925699 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619 		JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A affects expression ISO theaflavin-3,3'-digallate affects the expression of HTR5A mRNA CTD PMID:34925699 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651 		JBrowse link
G Hus1b HUS1 checkpoint clamp component B affects expression ISO theaflavin-3,3'-digallate affects the expression of HUS1B mRNA CTD PMID:34925699 NCBI chr17:33,534,032...33,535,199 JBrowse link
G Id3 inhibitor of DNA binding 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of ID3 mRNA CTD PMID:34925699 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Ier5l immediate early response 5-like affects expression ISO theaflavin-3,3'-digallate affects the expression of IER5L mRNA CTD PMID:34925699 NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647 		JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of IGDCC3 mRNA CTD PMID:34925699 NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959 		JBrowse link
G Il10 interleukin 10 affects expression
multiple interactions		 ISO theaflavin-3,3'-digallate affects the expression of IL10 mRNA
theaflavin-3,3'-digallate results in increased expression of and results in increased secretion of IL10 protein		 CTD PMID:33833684 PMID:34925699 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il13 interleukin 13 affects expression ISO theaflavin-3,3'-digallate affects the expression of IL13 mRNA CTD PMID:34925699 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il19 interleukin 19 affects expression ISO theaflavin-3,3'-digallate affects the expression of IL19 mRNA CTD PMID:34925699 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il1b interleukin 1 beta decreases secretion
multiple interactions		 ISO
EXP		 theaflavin-3,3'-digallate results in decreased secretion of IL1B protein
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of ACAN protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased abundance of and results in increased secretion of Dinoprostone]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of ADAMTS5 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of and results in decreased expression of NFKBIA protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL1B protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of TNF protein]
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]		 CTD PMID:27871911 PMID:30874838 PMID:33833684 PMID:35847580 PMID:37651426 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of IL2 mRNA CTD PMID:34925699 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of IL5RA mRNA CTD PMID:34925699 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion		 ISO
EXP		 theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
theaflavin-3,3'-digallate results in decreased secretion of IL6 protein		 CTD PMID:27871911 PMID:30874838 PMID:33833684 PMID:35847580 PMID:37651426 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inava innate immunity activator affects expression ISO theaflavin-3,3'-digallate affects the expression of INAVA mRNA CTD PMID:34925699 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Inhba inhibin subunit beta A affects expression ISO theaflavin-3,3'-digallate affects the expression of INHBA mRNA CTD PMID:34925699 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Insm2 INSM transcriptional repressor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of INSM2 mRNA CTD PMID:34925699 NCBI chr 6:72,973,861...72,976,453 JBrowse link
G Insyn2b inhibitory synaptic factor family member 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of INSYN2B mRNA CTD PMID:34925699 NCBI chr10:18,916,721...19,023,859
Ensembl chr10:19,003,131...19,022,139 		JBrowse link
G Iqcn IQ motif containing N affects expression ISO theaflavin-3,3'-digallate affects the expression of IQCN mRNA CTD PMID:34925699 NCBI chr16:18,716,519...18,733,971
Ensembl chr16:18,716,519...18,726,261 		JBrowse link
G Iqub IQ motif and ubiquitin domain containing affects expression ISO theaflavin-3,3'-digallate affects the expression of IQUB mRNA CTD PMID:34925699 NCBI chr 4:52,931,768...52,993,795
Ensembl chr 4:52,931,767...52,993,834 		JBrowse link
G Irgc immunity related GTPase cinema affects expression ISO theaflavin-3,3'-digallate affects the expression of IRGC mRNA CTD PMID:34925699 NCBI chr 1:80,020,114...80,025,797
Ensembl chr 1:80,020,079...80,025,802 		JBrowse link
G Itga2b integrin subunit alpha 2b affects expression ISO theaflavin-3,3'-digallate affects the expression of ITGA2B mRNA CTD PMID:34925699 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itgb6 integrin subunit beta 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of ITGB6 mRNA CTD PMID:34925699 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671 		JBrowse link
G Izumo1r IZUMO1 receptor, JUNO affects expression ISO theaflavin-3,3'-digallate affects the expression of IZUMO1R mRNA CTD PMID:34925699 NCBI chr 8:11,744,384...11,748,131
Ensembl chr 8:11,725,863...11,748,465 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of JAG2 mRNA CTD PMID:34925699 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of JUN protein] CTD PMID:27871911 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNE3 mRNA CTD PMID:34925699 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNJ6 mRNA CTD PMID:34925699 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Kcnk7 potassium two pore domain channel subfamily K member 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNK7 mRNA CTD PMID:34925699 NCBI chr 1:202,988,801...202,992,842
Ensembl chr 1:202,990,198...202,992,872 		JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of KCNT1 mRNA CTD PMID:34925699 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667 		JBrowse link
G Kiaa1614 KIAA1614 homolog affects expression ISO theaflavin-3,3'-digallate affects the expression of KIAA1614 mRNA CTD PMID:34925699 NCBI chr13:67,388,916...67,427,392
Ensembl chr13:67,389,044...67,421,272 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO theaflavin-3,3'-digallate affects the expression of KIT mRNA CTD PMID:34925699 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klk11 kallikrein related-peptidase 11 affects expression ISO theaflavin-3,3'-digallate affects the expression of KLK11 mRNA CTD PMID:34925699 NCBI chr 1:94,228,741...94,233,281
Ensembl chr 1:94,228,741...94,233,281 		JBrowse link
G Klk14 kallikrein related-peptidase 14 affects expression ISO theaflavin-3,3'-digallate affects the expression of KLK14 mRNA CTD PMID:34925699 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Krt79 keratin 79 affects expression ISO theaflavin-3,3'-digallate affects the expression of KRT79 mRNA CTD PMID:34925699 NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705 		JBrowse link
G Lair1 leukocyte-associated immunoglobulin-like receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of LAIR1 mRNA CTD PMID:34925699 NCBI chr 1:70,068,571...70,187,851
Ensembl chr 1:70,157,681...70,185,807 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of LAT2 mRNA CTD PMID:34925699 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Ldb2 LIM domain binding 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of LDB2 mRNA CTD PMID:34925699 NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778 		JBrowse link
G Ldhal6b lactate dehydrogenase A-like 6B affects expression ISO theaflavin-3,3'-digallate affects the expression of LDHAL6B mRNA CTD PMID:34925699 NCBI chr 1:45,997,845...45,999,268
Ensembl chr 1:45,991,991...45,999,272 		JBrowse link
G Lep leptin multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP1A2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP2C70 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of CYP4F14 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of DHCR7 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of EBP mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ELOVL1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FABP4 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FADS1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of LPL mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PLIN4 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PPARD mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of SCD1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TECR mRNA]; theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TM7SF2 mRNA] CTD PMID:36105184 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of LGR5 mRNA CTD PMID:34925699 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446 		JBrowse link
G Lilrb3 leukocyte immunoglobulin like receptor B3 affects expression ISO theaflavin-3,3'-digallate affects the expression of LILRB5 mRNA CTD PMID:34925699 NCBI chr 1:69,928,948...69,939,461
Ensembl chr 1:69,928,945...69,939,048 		JBrowse link
G Lman1l lectin, mannose-binding, 1 like affects expression ISO theaflavin-3,3'-digallate affects the expression of LMAN1L mRNA CTD PMID:34925699 NCBI chr 8:58,010,839...58,029,599
Ensembl chr 8:58,010,839...58,023,681 		JBrowse link
G LOC100912356 interferon alpha-1-like affects expression ISO theaflavin-3,3'-digallate affects the expression of IFNA5 mRNA CTD PMID:34925699 NCBI chr 5:103,227,820...103,230,500 JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of LPL mRNA] CTD PMID:36105184 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrp1b LDL receptor related protein 1B affects expression ISO theaflavin-3,3'-digallate affects the expression of LRP1B mRNA CTD PMID:34925699 NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Lrrc18 leucine rich repeat containing 18 affects expression ISO theaflavin-3,3'-digallate affects the expression of LRRC18 mRNA CTD PMID:34925699 NCBI chr16:8,253,524...8,277,141
Ensembl chr16:8,254,352...8,277,437 		JBrowse link
G Lrrc66 leucine rich repeat containing 66 affects expression ISO theaflavin-3,3'-digallate affects the expression of LRRC66 mRNA CTD PMID:34925699 NCBI chr14:34,578,934...34,604,977
Ensembl chr14:34,581,240...34,604,541 		JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of LSMEM1 mRNA CTD PMID:34925699 NCBI chr 6:57,251,720...57,261,590
Ensembl chr 6:57,252,056...57,261,653 		JBrowse link
G Ly9 lymphocyte antigen 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of LY9 mRNA CTD PMID:34925699 NCBI chr13:84,079,345...84,100,783
Ensembl chr13:84,079,458...84,100,823 		JBrowse link
G Mab21l3 mab-21 like 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of MAB21L3 mRNA CTD PMID:34925699 NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652 		JBrowse link
G Mafb MAF bZIP transcription factor B affects expression ISO theaflavin-3,3'-digallate affects the expression of MAFB mRNA CTD PMID:34925699 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of MALRD1 mRNA CTD PMID:34925699 NCBI chr17:78,418,819...79,131,015
Ensembl chr17:78,418,819...79,131,016 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
decreases expression		 ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of MAP1LC3B protein
theaflavin-3,3'-digallate results in decreased expression of MAP1LC3B protein		 CTD PMID:34350509 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression EXP theaflavin-3,3'-digallate results in decreased expression of MAP2K1 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAP2K1 protein CTD PMID:32964953 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression EXP theaflavin-3,3'-digallate results in decreased expression of MAP2K2 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAP2K2 protein CTD PMID:32964953 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression
decreases phosphorylation
multiple interactions		 EXP
ISO		 theaflavin-3,3'-digallate results in decreased expression of MAPK1 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAPK1 protein
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK1 protein
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK1 protein]
theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:16353237 PMID:30874838 PMID:32694992 PMID:32964953 PMID:33833684 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases expression
decreases phosphorylation		 ISO
EXP		 theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK3 protein]
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK3 protein]
theaflavin-3,3'-digallate results in decreased expression of MAPK3 mRNA; theaflavin-3,3'-digallate results in decreased expression of MAPK3 protein
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK3 protein		 CTD PMID:16353237 PMID:30874838 PMID:32694992 PMID:32964953 PMID:33833684 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
decreases phosphorylation		 EXP
ISO		 theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK8 protein]
theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK8 protein
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein]		 CTD PMID:27871911 PMID:32694992 PMID:35903325 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases phosphorylation ISO theaflavin-3,3'-digallate results in decreased phosphorylation of MAPK9 protein CTD PMID:30874838 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Matn4 matrilin 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of MATN4 mRNA CTD PMID:34925699 NCBI chr 3:153,120,605...153,135,628
Ensembl chr 3:153,120,632...153,135,865 		JBrowse link
G Mep1b meprin A subunit beta affects expression ISO theaflavin-3,3'-digallate affects the expression of MEP1B mRNA CTD PMID:34925699 NCBI chr18:12,366,126...12,392,840
Ensembl chr18:12,365,289...12,392,840 		JBrowse link
G Mgam maltase-glucoamylase affects expression ISO theaflavin-3,3'-digallate affects the expression of MGAM mRNA CTD PMID:34925699 NCBI chr 4:69,441,626...69,602,068
Ensembl chr 4:69,446,150...69,692,715 		JBrowse link
G Mia MIA SH3 domain containing affects expression ISO theaflavin-3,3'-digallate affects the expression of MIA mRNA CTD PMID:34925699 NCBI chr 1:82,473,677...82,476,378
Ensembl chr 1:82,473,678...82,475,370 		JBrowse link
G Mkx mohawk homeobox affects expression ISO theaflavin-3,3'-digallate affects the expression of MKX mRNA CTD PMID:34925699 NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124 		JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of MMP1 protein CTD PMID:30874838 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] CTD PMID:35847580 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp17 matrix metallopeptidase 17 affects expression ISO theaflavin-3,3'-digallate affects the expression of MMP17 mRNA CTD PMID:34925699 NCBI chr12:27,074,398...27,099,317
Ensembl chr12:27,074,409...27,099,316 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO theaflavin-3,3'-digallate results in decreased expression of MMP2 protein CTD PMID:30874838 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
decreases expression		 EXP
ISO		 theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of MMP3 protein]
theaflavin-3,3'-digallate results in decreased expression of MMP3 protein		 CTD PMID:30874838 PMID:35847580 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA] CTD PMID:32694992 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Morn3 MORN repeat containing 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of MORN3 mRNA CTD PMID:34925699 NCBI chr12:33,505,654...33,529,918
Ensembl chr12:33,514,230...33,529,931 		JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase affects expression ISO theaflavin-3,3'-digallate affects the expression of MOS mRNA CTD PMID:34925699 NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor affects expression ISO theaflavin-3,3'-digallate affects the expression of MPL mRNA CTD PMID:34925699 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797 		JBrowse link
G Mpzl2 myelin protein zero-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MPZL2 mRNA CTD PMID:34925699 NCBI chr 8:45,348,285...45,359,298
Ensembl chr 8:45,348,285...45,359,298 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MRAP2 mRNA CTD PMID:34925699 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Mroh2b maestro heat-like repeat family member 2B affects expression ISO theaflavin-3,3'-digallate affects the expression of MROH2B mRNA CTD PMID:34925699 NCBI chr 2:54,003,870...54,063,992
Ensembl chr 2:54,003,862...54,063,984 		JBrowse link
G Ms4a5 membrane spanning 4-domains A5 affects expression ISO theaflavin-3,3'-digallate affects the expression of MS4A5 mRNA CTD PMID:34925699 NCBI chr 1:207,927,057...207,934,886
Ensembl chr 1:207,927,052...207,934,836 		JBrowse link
G Mtfr2 mitochondrial fission regulator 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MTFR2 mRNA CTD PMID:34925699 NCBI chr 1:15,123,232...15,138,632
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MTOR protein] CTD PMID:35903325 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc13 mucin 13, cell surface associated affects expression ISO theaflavin-3,3'-digallate affects the expression of MUC13 mRNA CTD PMID:34925699 NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727 		JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming affects expression ISO theaflavin-3,3'-digallate affects the expression of MUC5B mRNA CTD PMID:34925699 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250 		JBrowse link
G Myadml2 myeloid-associated differentiation marker-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of MYADML2 mRNA CTD PMID:34925699 NCBI chr10:105,922,557...105,927,867
Ensembl chr10:105,925,947...105,927,575 		JBrowse link
G Mybphl myosin binding protein H-like affects expression ISO theaflavin-3,3'-digallate affects the expression of MYBPHL mRNA CTD PMID:34925699 NCBI chr 2:196,005,297...196,018,826
Ensembl chr 2:196,005,325...196,018,824 		JBrowse link
G Myh11 myosin heavy chain 11 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of MYH11 protein] CTD PMID:35903325 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459 		JBrowse link
G Mylk3 myosin light chain kinase 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of MYLK3 mRNA CTD PMID:34925699 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Myo1a myosin IA affects expression ISO theaflavin-3,3'-digallate affects the expression of MYO1A mRNA CTD PMID:34925699 NCBI chr 7:63,542,988...63,557,944
Ensembl chr 7:63,542,988...63,557,944 		JBrowse link
G Myo1f myosin IF affects expression ISO theaflavin-3,3'-digallate affects the expression of MYO1F mRNA CTD PMID:34925699 NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911 		JBrowse link
G Myod1 myogenic differentiation 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of MYOD1 mRNA CTD PMID:34925699 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Nalf2 NALCN channel auxiliary factor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NALF2 mRNA CTD PMID:34925699 NCBI chr  X:64,925,100...64,951,074
Ensembl chr  X:64,925,051...64,951,077 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of NCF4 mRNA CTD PMID:34925699 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389 		JBrowse link
G Nckap1l NCK associated protein 1 like affects expression ISO theaflavin-3,3'-digallate affects the expression of NCKAP1L mRNA CTD PMID:34925699 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Neurog2 neurogenin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NEUROG2 mRNA CTD PMID:34925699 NCBI chr 2:216,092,709...216,095,276
Ensembl chr 2:216,093,363...216,094,154 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in decreased phosphorylation of NFATC3 protein] CTD PMID:35406003 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression		 ISO
EXP		 [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] inhibits the reaction [TNFSF11 protein results in increased abundance of Reactive Oxygen Species]; [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] which results in decreased abundance of Reactive Oxygen Species; theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate results in increased expression of and affects the localization of NFE2L2 protein CTD PMID:32694992 PMID:35847580 PMID:36638877 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of and results in decreased expression of NFKBIA protein] CTD PMID:35847580 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkain3 Sodium/potassium transporting ATPase interacting 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of NKAIN3 mRNA CTD PMID:34925699 NCBI chr 5:33,613,720...34,310,090
Ensembl chr 5:33,623,713...34,309,381 		JBrowse link
G Nkx3-2 NK3 homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NKX3-2 mRNA CTD PMID:34925699 NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061 		JBrowse link
G Nlrp4 NLR family, pyrin domain containing 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of NLRP4 mRNA CTD PMID:34925699 NCBI chr 1:68,089,321...68,132,429
Ensembl chr 1:68,089,321...68,127,521 		JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of NLRP5 mRNA CTD PMID:34925699 NCBI chr 1:67,778,037...67,810,941
Ensembl chr 1:67,777,948...68,023,736 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:35847580 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase affects expression ISO theaflavin-3,3'-digallate affects the expression of NOTUM mRNA CTD PMID:34925699 NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315 		JBrowse link
G Nova2 NOVA alternative splicing regulator 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NOVA2 mRNA CTD PMID:34925699 NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of ANP mRNA] CTD PMID:35406003 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of BNP mRNA] CTD PMID:35406003 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of NR4A2 mRNA CTD PMID:34925699 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nrg1 neuregulin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of NRG1 mRNA CTD PMID:34925699 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of NUSAP1 mRNA CTD PMID:34925699 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Nxf7 nuclear RNA export factor 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of NXF5 mRNA CTD PMID:34925699 NCBI chr  X:98,535,374...98,552,562
Ensembl chr  X:98,535,375...98,552,526 		JBrowse link
G Olig1 oligodendrocyte transcription factor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of OLIG1 mRNA CTD PMID:34925699 NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521 		JBrowse link
G Omg oligodendrocyte-myelin glycoprotein affects expression ISO theaflavin-3,3'-digallate affects the expression of OMG mRNA CTD PMID:34925699 NCBI chr10:64,461,350...64,464,084
Ensembl chr10:64,461,350...64,464,084 		JBrowse link
G Opn1sw opsin 1, short wave sensitive affects expression ISO theaflavin-3,3'-digallate affects the expression of OPN1SW mRNA CTD PMID:34925699 NCBI chr 4:57,977,317...57,980,457
Ensembl chr 4:57,977,313...57,980,457 		JBrowse link
G Or2a25 olfactory receptor family 2 subfamily A member 25 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR2A25 mRNA CTD PMID:34925699 NCBI chr 4:71,878,578...71,879,519
Ensembl chr 4:71,878,578...71,879,519 		JBrowse link
G Or2k2 olfactory receptor family 2 subfamily K member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR2K2 mRNA CTD PMID:34925699 NCBI chr 5:73,582,686...73,583,627
Ensembl chr 5:73,581,080...73,585,725 		JBrowse link
G Or51i1 olfactory receptor family 51 subfamily I member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR51I1 mRNA CTD PMID:34925699 NCBI chr 1:158,502,581...158,503,525
Ensembl chr 1:158,502,362...158,506,799 		JBrowse link
G Or5b99 olfactory receptor family 5 subfamily B member 99 affects expression ISO theaflavin-3,3'-digallate affects the expression of OR5B2 mRNA CTD PMID:34925699 NCBI chr 1:210,136,841...210,137,767
Ensembl chr 1:210,132,946...210,138,365 		JBrowse link
G Otol1 otolin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of OTOL1 mRNA CTD PMID:34925699 NCBI chr 2:154,339,612...154,349,050
Ensembl chr 2:154,339,612...154,349,023 		JBrowse link
G Otor otoraplin affects expression ISO theaflavin-3,3'-digallate affects the expression of OTOR mRNA CTD PMID:34925699 NCBI chr 3:130,415,339...130,418,601
Ensembl chr 3:130,415,339...130,418,601 		JBrowse link
G Otp orthopedia homeobox affects expression ISO theaflavin-3,3'-digallate affects the expression of OTP mRNA CTD PMID:34925699 NCBI chr 2:26,108,158...26,116,359
Ensembl chr 2:26,108,163...26,116,359 		JBrowse link
G Otx2 orthodenticle homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of OTX2 mRNA CTD PMID:34925699 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Padi6 peptidyl arginine deiminase 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of PADI6 mRNA CTD PMID:34925699 NCBI chr 5:153,021,855...153,037,443
Ensembl chr 5:153,021,965...153,037,414 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO theaflavin-3,3'-digallate results in increased cleavage of PARP1 protein CTD PMID:30769778 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pate1 prostate and testis expressed 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PATE1 mRNA CTD PMID:34925699 NCBI chr 8:34,048,410...34,050,867
Ensembl chr 8:34,048,617...34,050,848 		JBrowse link
G Pax3 paired box 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of PAX3 mRNA CTD PMID:34925699 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Pbx4 PBX homeobox 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of PBX4 mRNA CTD PMID:34925699 NCBI chr16:19,555,089...19,590,054
Ensembl chr16:19,555,090...19,590,014 		JBrowse link
G Pcdha5 protocadherin alpha 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of PCDHA5 mRNA CTD PMID:34925699 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PCP4L1 mRNA CTD PMID:34925699 NCBI chr13:83,588,992...83,612,631
Ensembl chr13:83,588,992...83,609,966 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PCSK2 mRNA CTD PMID:34925699 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pde2a phosphodiesterase 2A affects expression ISO theaflavin-3,3'-digallate affects the expression of PDE2A mRNA CTD PMID:34925699 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde3a phosphodiesterase 3A affects expression ISO theaflavin-3,3'-digallate affects the expression of PDE3A mRNA CTD PMID:34925699 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of PDGFRB protein] CTD PMID:35903325 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pex5l peroxisomal biogenesis factor 5-like affects expression ISO theaflavin-3,3'-digallate affects the expression of PEX5L mRNA CTD PMID:34925699 NCBI chr 2:115,694,868...115,908,365
Ensembl chr 2:115,700,972...115,913,628 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PHOSPHO1 mRNA CTD PMID:34925699 NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342 		JBrowse link
G Pkd1l1 polycystin 1 like 1, transient receptor potential channel interacting affects expression ISO theaflavin-3,3'-digallate affects the expression of PKD1L1 mRNA CTD PMID:34925699 NCBI chr14:83,552,964...83,670,062
Ensembl chr14:83,545,469...83,638,498 		JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting affects expression ISO theaflavin-3,3'-digallate affects the expression of PKD1L3 mRNA CTD PMID:34925699 NCBI chr19:37,585,564...37,650,083
Ensembl chr19:37,585,725...37,650,155 		JBrowse link
G Pkdrej polycystin family receptor for egg jelly affects expression ISO theaflavin-3,3'-digallate affects the expression of PKDREJ mRNA CTD PMID:34925699 NCBI chr 7:116,909,094...116,915,468
Ensembl chr 7:116,909,094...116,915,468 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB affects expression ISO theaflavin-3,3'-digallate affects the expression of PLA2G12B mRNA CTD PMID:34925699 NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743 		JBrowse link
G Pla2g2f phospholipase A2, group IIF affects expression ISO theaflavin-3,3'-digallate affects the expression of PLA2G2F mRNA CTD PMID:34925699 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of PLCG1 protein] CTD PMID:35903325 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plekha6 pleckstrin homology domain containing A6 affects expression ISO theaflavin-3,3'-digallate affects the expression of PLEKHA6 mRNA CTD PMID:34925699 NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673 		JBrowse link
G Plin1 perilipin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PLIN1 mRNA CTD PMID:34925699 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828 		JBrowse link
G Plin4 perilipin 4 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PLIN4 mRNA] CTD PMID:36105184 NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056 		JBrowse link
G Plpp2 phospholipid phosphatase 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PLPP2 mRNA CTD PMID:34925699 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071 		JBrowse link
G Pmp2 peripheral myelin protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PMP2 mRNA CTD PMID:34925699 NCBI chr 2:91,611,334...91,615,252
Ensembl chr 2:91,611,334...91,615,252 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of PPARD mRNA] CTD PMID:36105184 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Ppef2 protein phosphatase with EF-hand domain 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PPEF2 mRNA CTD PMID:34925699 NCBI chr14:15,797,414...15,831,620
Ensembl chr14:15,797,435...15,831,491 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased expression of PPP3CA protein] CTD PMID:35406003 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prap1 proline-rich acidic protein 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PRAP1 mRNA CTD PMID:34925699 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of PRDX2 mRNA] CTD PMID:36638877 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of PRKAG3 mRNA CTD PMID:34925699 NCBI chr 9:76,295,715...76,304,959
Ensembl chr 9:76,295,715...76,304,959 		JBrowse link
G Prokr1 prokineticin receptor 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of PROKR1 mRNA CTD PMID:34925699 NCBI chr 4:120,022,301...120,033,367
Ensembl chr 4:120,021,747...120,033,379 		JBrowse link
G Proz protein Z, vitamin K-dependent plasma glycoprotein affects expression ISO theaflavin-3,3'-digallate affects the expression of PROZ mRNA CTD PMID:34925699 NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480 		JBrowse link
G Ptcra pre T-cell antigen receptor alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of PTCRA mRNA CTD PMID:34925699 NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:14,218,802...14,229,235 		JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of PTGDR2 mRNA CTD PMID:34925699 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213 		JBrowse link
G Ptgir prostaglandin I2 receptor affects expression ISO theaflavin-3,3'-digallate affects the expression of PTGIR mRNA CTD PMID:34925699 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:35847580 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated affects expression ISO theaflavin-3,3'-digallate affects the expression of PYGM mRNA CTD PMID:34925699 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368 		JBrowse link
G Pyy peptide YY affects expression ISO theaflavin-3,3'-digallate affects the expression of PYY mRNA CTD PMID:34925699 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family affects expression ISO theaflavin-3,3'-digallate affects the expression of RAB39A mRNA CTD PMID:34925699 NCBI chr 8:54,088,246...54,105,867
Ensembl chr 8:54,088,129...54,106,483 		JBrowse link
G Rab44 RAB44, member RAS oncogene family affects expression ISO theaflavin-3,3'-digallate affects the expression of RAB44 mRNA CTD PMID:34925699 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO CDKN1B promotes the reaction [theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein]; theaflavin-3,3'-digallate results in decreased expression of and results in decreased phosphorylation of RB1 protein CTD PMID:30769778 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of RBFOX3 mRNA CTD PMID:34925699 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935 		JBrowse link
G Rbp7 retinol binding protein 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of RBP7 mRNA CTD PMID:34925699 NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339 		JBrowse link
G Rcan2 regulator of calcineurin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of RCAN2 mRNA CTD PMID:34925699 NCBI chr 9:16,959,478...17,174,823
Ensembl chr 9:16,959,480...17,174,856 		JBrowse link
G Rcvrn recoverin affects expression ISO theaflavin-3,3'-digallate affects the expression of RCVRN mRNA CTD PMID:34925699 NCBI chr10:52,388,706...52,396,454
Ensembl chr10:52,388,706...52,396,453 		JBrowse link
G Rd3 RD3 regulator of GUCY2D affects expression ISO theaflavin-3,3'-digallate affects the expression of RD3 mRNA CTD PMID:34925699 NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP		 theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; theaflavin-3,3'-digallate results in decreased expression of and affects the localization of RELA protein
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]		 CTD PMID:27871911 PMID:30874838 PMID:35847580 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retn resistin multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Methylmercury Compounds results in increased secretion of RETN protein] CTD PMID:31195622 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rfx6 regulatory factor X, 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of RFX6 mRNA CTD PMID:34925699 NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Rgs18 regulator of G-protein signaling 18 affects expression ISO theaflavin-3,3'-digallate affects the expression of RGS18 mRNA CTD PMID:34925699 NCBI chr13:56,493,134...56,516,045
Ensembl chr13:56,494,010...56,516,098 		JBrowse link
G Rhoh ras homolog family member H affects expression ISO theaflavin-3,3'-digallate affects the expression of RHOH mRNA CTD PMID:34925699 NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369 		JBrowse link
G Rnf152 ring finger protein 152 affects expression ISO theaflavin-3,3'-digallate affects the expression of RNF152 mRNA CTD PMID:34925699 NCBI chr13:21,324,039...21,403,405
Ensembl chr13:21,323,824...21,403,113 		JBrowse link
G Rspo1 R-spondin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of RSPO1 mRNA CTD PMID:34925699 NCBI chr 5:137,251,629...137,273,273
Ensembl chr 5:137,251,659...137,272,933 		JBrowse link
G Rspo2 R-spondin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of RSPO2 mRNA CTD PMID:34925699 NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions
increases expression		 ISO theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of RUNX2 protein]
theaflavin-3,3'-digallate results in increased expression of RUNX2 protein		 CTD PMID:33833684 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of SCD1 mRNA] CTD PMID:36105184 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta affects expression ISO theaflavin-3,3'-digallate affects the expression of SCNN1B mRNA CTD PMID:34925699 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scx scleraxis bHLH transcription factor affects expression ISO theaflavin-3,3'-digallate affects the expression of SCX mRNA CTD PMID:34925699 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SDR42E1 mRNA CTD PMID:34925699 NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901 		JBrowse link
G Selp selectin P affects expression ISO theaflavin-3,3'-digallate affects the expression of SELP mRNA CTD PMID:34925699 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Selplg selectin P ligand affects expression ISO theaflavin-3,3'-digallate affects the expression of SELPLG mRNA CTD PMID:34925699 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585 		JBrowse link
G Serinc4 serine incorporator 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERINC4 mRNA CTD PMID:34925699 NCBI chr 3:108,428,896...108,434,778
Ensembl chr 3:108,428,897...108,434,778 		JBrowse link
G Serpina6 serpin family A member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINA6 mRNA CTD PMID:34925699 NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349 		JBrowse link
G Serpinb10 serpin family B member 10 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINB10 mRNA CTD PMID:34925699 NCBI chr13:23,553,348...23,571,182
Ensembl chr13:23,553,430...23,571,182 		JBrowse link
G Serpinb5 serpin family B member 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINB5 mRNA CTD PMID:34925699 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756 		JBrowse link
G Serpinc1 serpin family C member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SERPINC1 mRNA CTD PMID:34925699 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Sfn stratifin affects expression ISO theaflavin-3,3'-digallate affects the expression of SFN mRNA CTD PMID:34925699 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sh2d4b SH2 domain containing 4B affects expression ISO theaflavin-3,3'-digallate affects the expression of SH2D4B mRNA CTD PMID:34925699 NCBI chr16:16,673,518...16,783,076
Ensembl chr16:16,677,889...16,769,087 		JBrowse link
G Sh2d7 SH2 domain containing 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of SH2D7 mRNA CTD PMID:34925699 NCBI chr 8:54,918,399...54,930,129
Ensembl chr 8:54,918,406...54,929,726 		JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SIGLEC1 mRNA CTD PMID:34925699 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850 		JBrowse link
G Slamf8 SLAM family member 8 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLAMF8 mRNA CTD PMID:34925699 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211 		JBrowse link
G Slc10a6 solute carrier family 10 member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC10A6 mRNA CTD PMID:34925699 NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC17A8 mRNA CTD PMID:34925699 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC20A1 mRNA CTD PMID:34925699 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC22A13 mRNA CTD PMID:34925699 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
G Slc22a20 solute carrier family 22 member 20 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC22A20 mRNA CTD PMID:34925699 NCBI chr 1:203,257,374...203,273,854
Ensembl chr 1:203,257,374...203,273,822 		JBrowse link
G Slc35f3 solute carrier family 35, member F3 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC35F3 mRNA CTD PMID:34925699 NCBI chr19:54,102,811...54,371,765
Ensembl chr19:54,103,120...54,372,839 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC45A2 mRNA CTD PMID:34925699 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A12 mRNA CTD PMID:34925699 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A13 mRNA CTD PMID:34925699 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc6a20a solute carrier family 6 member 20a affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A20 mRNA CTD PMID:34925699 NCBI chr 8:123,282,325...123,322,609
Ensembl chr 8:123,281,472...123,322,573 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A3 mRNA CTD PMID:34925699 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A4 mRNA CTD PMID:34925699 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slc6a7 solute carrier family 6 member 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLC6A7 mRNA CTD PMID:34925699 NCBI chr18:54,448,464...54,467,319
Ensembl chr18:54,448,464...54,467,319 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLCO1A2 mRNA CTD PMID:34925699 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLCO2B1 mRNA CTD PMID:34925699 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Slit1 slit guidance ligand 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SLIT1 mRNA CTD PMID:34925699 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Smim23 small integral membrane protein 23 affects expression ISO theaflavin-3,3'-digallate affects the expression of SMIM23 mRNA CTD PMID:34925699 NCBI chr10:17,403,456...17,407,091
Ensembl chr10:17,403,456...17,407,168 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [Galactose results in decreased expression of SOD1 mRNA] CTD PMID:36638877 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP theaflavin-3,3'-digallate results in increased expression of SOD2 protein CTD PMID:35847580 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sostdc1 sclerostin domain containing 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of SOSTDC1 mRNA CTD PMID:34925699 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579 		JBrowse link
G Sowaha sosondowah ankyrin repeat domain family member A affects expression ISO theaflavin-3,3'-digallate affects the expression of SOWAHA mRNA CTD PMID:34925699 NCBI chr10:37,641,823...37,645,390
Ensembl chr10:37,643,444...37,645,102 		JBrowse link
G Sowahb sosondowah ankyrin repeat domain family member B affects expression ISO theaflavin-3,3'-digallate affects the expression of SOWAHB mRNA CTD PMID:34925699 NCBI chr14:15,029,203...15,033,038
Ensembl chr14:15,029,395...15,031,698 		JBrowse link
G Sox15 SRY-box transcription factor 15 affects expression ISO theaflavin-3,3'-digallate affects the expression of SOX15 mRNA CTD PMID:34925699 NCBI chr10:54,373,045...54,374,749
Ensembl chr10:54,372,403...54,376,591 		JBrowse link
G Sox30 SRY-box transcription factor 30 affects expression ISO theaflavin-3,3'-digallate affects the expression of SOX30 mRNA CTD PMID:34925699 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in decreased expression of SOX9 protein] CTD PMID:35847580 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [EGF protein results in increased activity of SP1 protein] CTD PMID:12931129 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of SP7 protein] CTD PMID:33833684 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847 		JBrowse link
G Spacdr sperm acrosome developmental regulator affects expression ISO theaflavin-3,3'-digallate affects the expression of SPACDR mRNA CTD PMID:34925699 NCBI chr12:18,930,608...18,936,787
Ensembl chr12:18,914,398...18,952,008 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A affects expression ISO theaflavin-3,3'-digallate affects the expression of SPDYA mRNA CTD PMID:34925699 NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850 		JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of SPINK2 mRNA CTD PMID:34925699 NCBI chr14:30,967,682...30,974,326
Ensembl chr14:30,967,714...30,974,326 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of SPRY4 mRNA CTD PMID:34925699 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004 		JBrowse link
G Spx spexin hormone affects expression ISO theaflavin-3,3'-digallate affects the expression of SPX mRNA CTD PMID:34925699 NCBI chr 4:175,356,044...175,362,082
Ensembl chr 4:175,356,247...175,362,082 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of SQSTM1 protein CTD PMID:34350509 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of SRC protein] CTD PMID:35903325 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sst somatostatin affects expression ISO theaflavin-3,3'-digallate affects the expression of SST mRNA CTD PMID:34925699 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of ST8SIA6 mRNA CTD PMID:34925699 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299 		JBrowse link
G Stab1 stabilin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of STAB1 mRNA CTD PMID:34925699 NCBI chr16:6,330,435...6,360,934
Ensembl chr16:6,330,444...6,360,923 		JBrowse link
G Stac2 SH3 and cysteine rich domain 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of STAC2 mRNA CTD PMID:34925699 NCBI chr10:83,032,418...83,048,260
Ensembl chr10:83,032,417...83,048,260 		JBrowse link
G Stk31 serine threonine kinase 31 affects expression ISO theaflavin-3,3'-digallate affects the expression of STK31 mRNA CTD PMID:34925699 NCBI chr 4:78,370,691...78,467,599
Ensembl chr 4:78,370,649...78,466,240 		JBrowse link
G Stk32b serine/threonine kinase 32B affects expression ISO theaflavin-3,3'-digallate affects the expression of STK32B mRNA CTD PMID:34925699 NCBI chr14:73,077,944...73,337,976
Ensembl chr14:73,078,061...73,336,458 		JBrowse link
G Svopl SVOP like affects expression ISO theaflavin-3,3'-digallate affects the expression of SVOPL mRNA CTD PMID:34925699 NCBI chr 4:66,697,550...66,751,699
Ensembl chr 4:66,698,177...66,758,978 		JBrowse link
G Sycp2 synaptonemal complex protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of SYCP2 mRNA CTD PMID:34925699 NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789 		JBrowse link
G Sycp3 synaptonemal complex protein 3 affects expression ISO theaflavin-3,3'-digallate affects the expression of SYCP3 mRNA CTD PMID:34925699 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511 		JBrowse link
G Syndig1l synapse differentiation inducing 1-like affects expression ISO theaflavin-3,3'-digallate affects the expression of SYNDIG1L mRNA CTD PMID:34925699 NCBI chr 6:104,318,096...104,344,989
Ensembl chr 6:104,323,424...104,344,891 		JBrowse link
G Tac4 tachykinin precursor 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of TAC4 mRNA CTD PMID:34925699 NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156 		JBrowse link
G Tagln transgelin multiple interactions EXP theaflavin-3,3'-digallate inhibits the reaction [PDGFBB protein results in decreased expression of TAGLN protein] CTD PMID:35903325 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tcaf2 TRPM8 channel-associated factor 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TCAF2 mRNA CTD PMID:34925699
G Tead4 TEA domain transcription factor 4 affects expression ISO theaflavin-3,3'-digallate affects the expression of TEAD4 mRNA CTD PMID:34925699 NCBI chr 4:161,474,122...161,572,837
Ensembl chr 4:161,497,851...161,572,323 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TECR mRNA] CTD PMID:36105184 NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Tecta tectorin alpha affects expression ISO theaflavin-3,3'-digallate affects the expression of TECTA mRNA CTD PMID:34925699 NCBI chr 8:42,707,962...42,779,726
Ensembl chr 8:42,707,962...42,779,707 		JBrowse link
G Tef TEF transcription factor, PAR bZIP family member affects expression ISO theaflavin-3,3'-digallate affects the expression of TEF mRNA CTD PMID:34925699 NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783 		JBrowse link
G Tex29 testis expressed 29 affects expression ISO theaflavin-3,3'-digallate affects the expression of TEX29 mRNA CTD PMID:34925699 NCBI chr16:77,650,471...77,664,171
Ensembl chr16:77,650,473...77,664,116 		JBrowse link
G Tll2 tolloid-like 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TLL2 mRNA CTD PMID:34925699 NCBI chr 1:239,912,648...240,028,168
Ensembl chr 1:239,915,508...240,028,120 		JBrowse link
G Tlr9 toll-like receptor 9 affects expression ISO theaflavin-3,3'-digallate affects the expression of TLR9 mRNA CTD PMID:34925699 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 multiple interactions ISO theaflavin-3,3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of TM7SF2 mRNA] CTD PMID:36105184 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270 		JBrowse link
G Tmem119 transmembrane protein 119 affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM119 mRNA CTD PMID:34925699 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689 		JBrowse link
G Tmem132e transmembrane protein 132E affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM132E mRNA CTD PMID:34925699 NCBI chr10:67,330,863...67,386,790
Ensembl chr10:67,330,751...67,386,789 		JBrowse link
G Tmem150b transmembrane protein 150B affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM150B mRNA CTD PMID:34925699 NCBI chr 1:69,124,943...69,134,617
Ensembl chr 1:69,125,710...69,141,034 		JBrowse link
G Tmem151a transmembrane protein 151A affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM151A mRNA CTD PMID:34925699 NCBI chr 1:202,387,397...202,392,182
Ensembl chr 1:202,388,240...202,392,182 		JBrowse link
G Tmem178b transmembrane protein 178B affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM178B mRNA CTD PMID:34925699 NCBI chr 4:68,659,425...69,035,690
Ensembl chr 4:68,657,343...69,035,690 		JBrowse link
G Tmem40 transmembrane protein 40 affects expression ISO theaflavin-3,3'-digallate affects the expression of TMEM40 mRNA CTD PMID:34925699 NCBI chr 4:148,791,509...148,819,287
Ensembl chr 4:148,791,505...148,823,665 		JBrowse link
G Tmprss7 transmembrane serine protease 7 affects expression ISO theaflavin-3,3'-digallate affects the expression of TMPRSS7 mRNA CTD PMID:34925699 NCBI chr11:55,127,992...55,166,597
Ensembl chr11:55,128,998...55,164,882 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases secretion
affects expression		 ISO
EXP		 theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]
theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of BGLAP protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of CTNNB1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of RUNX2 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased expression of SP7 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK1 protein]; theaflavin-3,3'-digallate inhibits the reaction [TNF protein results in decreased phosphorylation of MAPK3 protein]; theaflavin-3,3'-digallate results in decreased expression of and results in decreased secretion of TNF protein
theaflavin-3,3'-digallate results in decreased secretion of TNF protein
theaflavin-3,3'-digallate affects the expression of TNF mRNA
theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; theaflavin-3,3'-digallate inhibits the reaction [IL1B protein results in increased secretion of TNF protein]		 CTD PMID:27871911 PMID:30874838 PMID:33833684 PMID:34925699 PMID:35847580 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A affects expression ISO theaflavin-3,3'-digallate affects the expression of TNFRSF11A mRNA CTD PMID:34925699 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [theaflavin-3,3'-digallate results in increased expression of NFE2L2 protein] inhibits the reaction [TNFSF11 protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of GPX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CD40 mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; theaflavin-3,3'-digallate inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA] CTD PMID:32694992 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TOGARAM2 mRNA CTD PMID:34925699 NCBI chr 6:23,770,979...23,828,884
Ensembl chr 6:23,771,052...23,828,499 		JBrowse link
G Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of TUSC5 mRNA CTD PMID:34925699 NCBI chr10:61,521,107...61,541,494
Ensembl chr10:61,521,107...61,541,494 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TREM2 mRNA CTD PMID:34925699 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim31 tripartite motif-containing 31 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRIM31 mRNA CTD PMID:34925699 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim36 tripartite motif-containing 36 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRIM36 mRNA CTD PMID:34925699 NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859 		JBrowse link
G Trim72 tripartite motif containing 72 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRIM72 mRNA CTD PMID:34925699 NCBI chr 1:182,613,753...182,621,613
Ensembl chr 1:182,613,712...182,621,606 		JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRPM6 mRNA CTD PMID:34925699 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 affects expression ISO theaflavin-3,3'-digallate affects the expression of TRPV5 mRNA CTD PMID:34925699 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745 		JBrowse link
G Tspo2 translocator protein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of TSPO2 mRNA CTD PMID:34925699 NCBI chr 9:12,544,615...12,548,563
Ensembl chr 9:12,545,015...12,548,573 		JBrowse link
G Ttc22 tetratricopeptide repeat domain 22 affects expression ISO theaflavin-3,3'-digallate affects the expression of TTC22 mRNA CTD PMID:34925699 NCBI chr 5:121,401,973...121,423,130
Ensembl chr 5:121,406,326...121,423,130 		JBrowse link
G Uts2 urotensin 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of UTS2 mRNA CTD PMID:34925699 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases secretion
multiple interactions		 ISO theaflavin-3,3'-digallate results in decreased secretion of VEGFA protein
[Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased secretion of VEGFA protein		 CTD PMID:34350509 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vil1 villin 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of VIL1 mRNA CTD PMID:34925699 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
G Vsig2 V-set and immunoglobulin domain containing 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of VSIG2 mRNA CTD PMID:34925699 NCBI chr 8:37,250,107...37,255,150
Ensembl chr 8:37,250,107...37,255,150 		JBrowse link
G Vsnl1 visinin-like 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of VSNL1 mRNA CTD PMID:34925699 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
G Vsx2 visual system homeobox 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of VSX2 mRNA CTD PMID:34925699 NCBI chr 6:104,214,842...104,240,264
Ensembl chr 6:104,217,230...104,240,018 		JBrowse link
G Vwa3a von Willebrand factor A domain containing 3A affects expression ISO theaflavin-3,3'-digallate affects the expression of VWA3A mRNA CTD PMID:34925699 NCBI chr 1:175,293,782...175,355,588
Ensembl chr 1:175,293,873...175,355,602 		JBrowse link
G Wdr38 WD repeat domain 38 affects expression ISO theaflavin-3,3'-digallate affects the expression of WDR38 mRNA CTD PMID:34925699 NCBI chr 3:22,750,150...22,753,260
Ensembl chr 3:22,749,396...22,753,259 		JBrowse link
G Wdr86 WD repeat domain 86 affects expression ISO theaflavin-3,3'-digallate affects the expression of WDR86 mRNA CTD PMID:34925699 NCBI chr 4:10,423,496...10,443,473
Ensembl chr 4:10,424,008...10,441,465 		JBrowse link
G Wnt16 Wnt family member 16 affects expression ISO theaflavin-3,3'-digallate affects the expression of WNT16 mRNA CTD PMID:34925699 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Wnt6 Wnt family member 6 affects expression ISO theaflavin-3,3'-digallate affects the expression of WNT6 mRNA CTD PMID:34925699 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
G Wnt7a Wnt family member 7A affects expression ISO theaflavin-3,3'-digallate affects the expression of WNT7A mRNA CTD PMID:34925699 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
G Wt1 WT1 transcription factor affects expression ISO theaflavin-3,3'-digallate affects the expression of WT1 mRNA CTD PMID:34925699 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO [Methotrexate co-treated with theaflavin-3,3'-digallate] results in decreased expression of and results in decreased splicing of XBP1 mRNA; theaflavin-3,3'-digallate results in decreased expression of and results in decreased splicing of XBP1 mRNA CTD PMID:34350509 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Zar1 zygote arrest 1 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZAR1 mRNA CTD PMID:34925699 NCBI chr14:35,193,446...35,197,382
Ensembl chr14:35,193,446...35,197,382 		JBrowse link
G Zar1l zygote arrest 1-like affects expression ISO theaflavin-3,3'-digallate affects the expression of ZAR1L mRNA CTD PMID:34925699 NCBI chr12:46,534...56,434
Ensembl chr12:46,534...56,425 		JBrowse link
G Zfp385c zinc finger protein 385C affects expression ISO theaflavin-3,3'-digallate affects the expression of ZNF385C mRNA CTD PMID:34925699 NCBI chr10:85,562,003...85,618,100
Ensembl chr10:85,562,820...85,582,986 		JBrowse link
G Zfyve28 zinc finger FYVE-type containing 28 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZFYVE28 mRNA CTD PMID:34925699 NCBI chr14:76,468,424...76,554,039
Ensembl chr14:76,468,424...76,554,039 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 affects expression ISO theaflavin-3,3'-digallate affects the expression of ZP2 mRNA CTD PMID:34925699 NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      molecular entity 19806
        polyatomic entity 19764
          heteroatomic molecular entity 19720
            hydroxides 19299
              organic hydroxy compound 18923
                hydroxyflavan 3377
                  catechin 3356
                    Theaflavin 3,3'-digallate 514
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic heterocyclic compound 18848
                                  oxacycle 17866
                                    benzopyran 11952
                                      1-benzopyran 11704
                                        flavonoid 7190
                                          flavans 3634
                                            hydroxyflavan 3377
                                              catechin 3356
                                                Theaflavin 3,3'-digallate 514
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