C5ar2 (complement C5a receptor 2)

Gene: C5ar2 (complement C5a receptor 2) Rattus norvegicus

Analyze

Symbol:

C5ar2

Name:

complement C5a receptor 2

RGD ID:

1303027

Description:

Predicted to enable G protein-coupled receptor activity and complement component C5a receptor activity. Predicted to be involved in several processes, including complement receptor mediated signaling pathway; negative regulation of neutrophil chemotaxis; and regulation of cytokine production. Predicted to be located in apical part of cell and basal plasma membrane. Predicted to be active in plasma membrane. Orthologous to human C5AR2 (complement C5a receptor 2); INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5A receptor beta; C5L2; complement 5A receptor beta; complement component 5a receptor 2; G protein-coupled receptor 77; G-protein coupled receptor 77; Gpr77

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	C5AR2 (complement C5a receptor 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	C5ar2 (complement component 5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	C5ar2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	C5AR2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	C5AR2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	C5ar2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	C5AR2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	C5AR2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	C5ar2 (complement C5a receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	FPR3 (formyl peptide receptor 3)	HGNC	PhylomeDB
Alliance orthologs ³
Homo sapiens (human):	C5AR2 (complement C5a receptor 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	C5ar2 (complement component 5a receptor 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,058,557 - 86,073,583 (-)	NCBI		GRCr8
mRatBN7.2	1	76,930,381 - 76,945,432 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	76,930,383 - 76,959,517 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	82,306,213 - 82,317,469 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	90,870,245 - 90,881,501 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,061,319 - 84,072,573 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,165,155 - 78,183,426 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,166,810 - 78,180,216 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	79,431,191 - 79,448,689 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	71,422,103 - 71,432,305 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R)-noradrenaline (EXP)

1,2-dichloroethane (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chrysene (ISO)

Dibutyl phosphate (ISO)

endosulfan (EXP)

furan (EXP)

gentamycin (EXP)

iron dichloride (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

methoxychlor (EXP)

Muraglitazar (EXP)

obeticholic acid (ISO)

paracetamol (EXP,ISO)

PCB138 (EXP)

progesterone (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

Tesaglitazar (EXP)

testosterone (EXP,ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

Theaflavin 3,3'-digallate (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (EXP)

valproic acid (ISO)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chemotaxis (IEA)

complement component C5a signaling pathway (IEA)

complement receptor mediated signaling pathway (IBA,IEA)

G protein-coupled receptor signaling pathway (IEA,TAS)

inflammatory response (IBA)

negative regulation of interleukin-6 production (ISO,ISS)

negative regulation of neutrophil chemotaxis (ISO,ISS)

negative regulation of tumor necrosis factor production (ISO,ISS)

phospholipase C-activating G protein-coupled receptor signaling pathway (IBA)

positive regulation of cytosolic calcium ion concentration (IBA)

regulation of interleukin-8 production (ISO,ISS)

Cellular Component

apical part of cell (ISO,ISS)

basal plasma membrane (ISO,ISS)

membrane (IEA)

plasma membrane (IBA)

vesicle (IEA)

Molecular Function

complement component C5a receptor activity (IBA)

complement receptor activity (IEA)

G protein-coupled receptor activity (IBA,IEA,TAS)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	C5L2, a nonsignaling C5A binding protein.	Okinaga S, etal., Biochemistry 2003 Aug 12;42(31):9406-15.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15634936	PMID:15715664	PMID:15784721	PMID:16204243	PMID:17068344	PMID:17158873	PMID:19020281	PMID:22099750	PMID:22496247	PMID:22960554

Genomics

Comparative Map Data

C5ar2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,058,557 - 86,073,583 (-)	NCBI		GRCr8
mRatBN7.2	1	76,930,381 - 76,945,432 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	76,930,383 - 76,959,517 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	82,306,213 - 82,317,469 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	90,870,245 - 90,881,501 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,061,319 - 84,072,573 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,165,155 - 78,183,426 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,166,810 - 78,180,216 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	79,431,191 - 79,448,689 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	71,422,103 - 71,432,305 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

C5AR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	47,332,175 - 47,347,329 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	47,332,175 - 47,347,329 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	47,835,432 - 47,850,586 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	52,532,211 - 52,537,112 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	52,532,210 - 52,537,112	NCBI
Celera	19	44,644,255 - 44,649,165 (+)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	44,259,688 - 44,269,832 (+)	NCBI		HuRef
CHM1_1	19	47,837,590 - 47,847,456 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	50,157,644 - 50,172,793 (+)	NCBI		T2T-CHM13v2.0

C5ar2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	15,968,512 - 15,978,079 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	15,968,510 - 15,978,079 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	16,234,587 - 16,244,154 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	16,234,585 - 16,244,154 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	16,819,934 - 16,829,503 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	15,393,248 - 15,402,676 (-)	NCBI		MGSCv36	mm8
Celera	7	13,426,639 - 13,438,094 (-)	NCBI		Celera
Cytogenetic Map	7	A2	NCBI
cM Map	7	8.77	NCBI

C5ar2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955574	1,221,950 - 1,242,547 (+)	NCBI	ChiLan1.0	ChiLan1.0

C5AR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	53,479,345 - 53,490,765 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	55,349,344 - 55,360,769 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	44,320,315 - 44,331,732 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	52,976,049 - 52,985,506 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	52,984,180 - 52,985,193 (+)	Ensembl	panpan1.1		panPan2

C5AR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	108,644,195 - 108,652,628 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	108,644,945 - 108,645,958 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	108,125,820 - 108,134,033 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	109,170,540 - 109,178,740 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	109,171,219 - 109,172,232 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	108,837,514 - 108,845,719 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	108,481,845 - 108,490,056 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	109,350,410 - 109,358,627 (-)	NCBI		UU_Cfam_GSD_1.0

C5ar2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	19,419,605 - 19,432,306 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	1,047,997 - 1,049,016 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	1,047,997 - 1,050,612 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

C5AR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	53,123,162 - 53,127,051 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	53,118,063 - 53,125,574 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	48,539,085 - 48,551,849 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

C5AR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	40,659,576 - 40,672,267 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	40,671,056 - 40,672,069 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	20,393,696 - 20,406,527 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

C5ar2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	6,403,621 - 6,404,631 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	6,403,002 - 6,411,399 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in C5ar2
117 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	155
Count of miRNA genes:	118
Interacting mature miRNAs:	129
Transcripts:	ENSRNOT00000071576
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	35239598	78430678	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	53895117	82174945	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	35239598	78430678	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	33449848	78449848	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	72197680	90508767	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	45803140	78430678	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	28879780	78430678	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	49361465	82174945	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	34836858	79836858	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	33449848	78449848	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	53895117	82174945	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			10	10	8	10					4	8
Low	2	42	47	31	11	31	2	2	47	31	35	3	2
Below cutoff	1	1					6	9	27	4	2		6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY600435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY741660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000071576 ⟹ ENSRNOP00000067721

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	76,932,025 - 76,945,620 (-)	Ensembl
Rnor_6.0 Ensembl	1	78,166,810 - 78,180,216 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099386 ⟹ ENSRNOP00000088875

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	76,932,025 - 76,959,517 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102131 ⟹ ENSRNOP00000081314

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	76,930,383 - 76,942,972 (-)	Ensembl

RefSeq Acc Id:

NM_001003710 ⟹ NP_001003710

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,060,211 - 86,070,553 (-)	NCBI
mRatBN7.2	1	76,932,037 - 76,942,381 (-)	NCBI
Rnor_6.0	1	78,166,809 - 78,180,216 (-)	NCBI
Rnor_5.0	1	79,431,191 - 79,448,689 (-)	NCBI
Celera	1	71,422,103 - 71,432,305 (-)	RGD

Sequence:

show sequence

GGCACGAGGGTTGGATTGGCGAGACTCACACCCACGACTGTCCCTGGTGGAGAGACTCTGGGCC
TCCCTGTGTACTTGTTAGCGGCATTCAGCCAACGTGGGAGCAGTCGGAAGAGAAGGTGTCTGGG
GCCAGGATGCTGAACGACACCACCAGCAAGGATTATGAGTATGAGTATGATCAGGAACAGTATA
GTGACCTTCTGAACGTCCCCGTAGACTGCCCAGCTGGCAACTGCTTCTCTAATGATGCCTACCT
CATAGTCCTGCTTGGCCTGTATTCAGTCATCTTCCTGGTGGGTGTGCCAGGCAACACCCTGTTG
GCGTGGGTGACCTGGAAAGAGTCTCGCCACAGGCTCGGGGCCTCTTGGTTCCTGCACTTGACCA
TGGCGGACTTGCTTTGCTGTGTGTCTCTGCCCTTCCTGGCTGTGCCCATCGCCCAAAAGGGCCA
CTGGCCATACGGGACAGCAGGCTGCTGGCTGTTGTCCTCCATCACCGTTCTGTCTATGTATGCC
AGTGTGCTGCTCCTGACGGGCCTCAGTGGCGACCTCTTCCTATTGGCTTTCAGGCCCTCCTGGA
AGAATGCAGATCAACGAACATGTGGGGTGCGTGTGGTCCAGGTCTCCTCCTGGATGCTGGCCCT
GTTGCTGACTGTGCCTGGTGCTGTCTATCGTAAGCTGCTTCAGGAGCACTATCCTCCCCGGCTT
GTGTGTGGCACAAACTATGGGGGATCGGTCACCGCGGAAGTTACCATCACCACTGTTCGATTCC
TCTTTGGCTTCCTGGTGCCATTGGTGTTCATGGCCAGTTGCCACGGCATCCTCCAACGGCAGAT
GGCTCGCCGCCACTGGCCCCTGGGCACAGCTGTTGTGGTGGGGTTTTTCATTTGCTGGACCCCT
TTTCACCTCCTGCGGGTCATCATTGCAGTGGCTTTTTCACACTCCCCGCTCCTTGCCTGGGCCC
TGGAGGCTGAGCCTTTGGTTACGGGCCTGGCCCTTGCTCACAGTGCTCTCAATCCTATTATGTT
TTTGAATTTCGGAAGAAAACAACTCTGCAAGTCACTCCAGGCTGCATGTCACTGGGCCCTGAGG
GATCTACAGGATGAAGAGGAAAGTGCCGTGACCAAGGTATCCACCAGCCAGGAAATGGTGTCTG
AGATGCCGGTGTAGGCGGGAGGGATTTGGATTTCCTAGGCCAACCTCACAAACTGTGCAAGCTT
TCAGGGCAACAAGCTTGGAATGCAAGGAACCTCCGGAGATGGCTTTTATTCTTCGTTCAATAAA
CATTACATTGTGCAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006228352 ⟹ XP_006228414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,058,557 - 86,073,583 (-)	NCBI
mRatBN7.2	1	76,930,381 - 76,945,432 (-)	NCBI
Rnor_6.0	1	78,165,155 - 78,183,426 (-)	NCBI
Rnor_5.0	1	79,431,191 - 79,448,689 (-)	NCBI

Sequence:

show sequence

GAAAGAAAGAAAAGAAATGGGCATACAGTAGGTGATGGCTATGGCGGGAACCCCCTACCCCAGG
TGACCCACAGGCAGGTTAGGGTTAAGCAACAGTGTCCAAAACAGAAGTTAGCAGAGTCCAGGGG
ATTGCCAAATGTGTGGCCTGAGGAATCTGCTATGTCAACAGGTTTGGAAGGGGAAGTGAGCAGG
AAAGGAAGTGGGCTGAGGGCTTGGCAGACTCTAGCATATTCTTTCCCCTCCCCCAGCCCCAGCC
TTCTGGACCCTTGGGTCTTACATACCTACCTGTTCTTCAGATGTAGGGCTCCAAGGCCTGGAGC
CAGAGCTGCCTTCCCTTGTATTGGTGACCTCCAGGAGCTCACGTCCAGGAAGTTATTACTCTGC
AGTAGAGTCTTCTGGGATGAACTATGAGGGGCTGGGAGACGGTTCAGTGAGTAAAGTGTTTGCT
ATTCAAACAGAAGGGCATGACTTCCAGCCCCAGGACGTGGATATGTCCAGCACAGAGCTACGCA
CGGTGTCTGGGGCCAGGATGCTGAACGACACCACCAGCAAGGATTATGAGTATGAGTATGATCA
GGAACAGTATAGTGACCTTCTGAACGTCCCCGTAGACTGCCCAGCTGGCAACTGCTTCTCTAAT
GATGCCTACCTCATAGTCCTGCTTGGCCTGTATTCAGTCATCTTCCTGGTGGGTGTGCCAGGCA
ACACCCTGTTGGCGTGGGTGACCTGGAAAGAGTCTCGCCACAGGCTCGGGGCCTCTTGGTTCCT
GCACTTGACCATGGCGGACTTGCTTTGCTGTGTGTCTCTGCCCTTCCTGGCTGTGCCCATCGCC
CAAAAGGGCCACTGGCCATACGGGACAGCAGGCTGCTGGCTGTTGTCCTCCATCACCGTTCTGT
CTATGTATGCCAGTGTGCTGCTCCTGACGGGCCTCAGTGGCGACCTCTTCCTATTGGCTTTCAG
GCCCTCCTGGAAGAATGCAGATCAACGAACATGTGGGGTGCGTGTGGTCCAGGTCTCCTCCTGG
ATGCTGGCCCTGTTGCTGACTGTGCCTGGTGCTGTCTATCGTAAGCTGCTTCAGGAGCACTATC
CTCCCCGGCTTGTGTGTGGCACAAACTATGGGGGATCGGTCACCGCGGAAGTTACCATCACCAC
TGTTCGATTCCTCTTTGGCTTCCTGGTGCCATTGGTGTTCATGGCCAGTTGCCACGGCATCCTC
CAACGGCAGATGGCTCGCCGCCACTGGCCCCTGGGCACAGCTGTTGTGGTGGGGTTTTTCATTT
GCTGGACCCCTTTTCACCTCCTGCGGGTCATCATTGCAGTGGCTTCTTCACACTCCCCGCTCCT
TGCCTGGGCCCTGGAGGCTGAGCCTTTGGTTACGGGCCTGGCCCTTGCTCACAGTGCTCTCAAT
CCTATTATGTTTTTGTATTTCGGAAGAAAACAACTCTGCAAGTCACTCCAGGCTGCATGTCACT
GGGCCCTGAGGGATCTACAGGATGAGGAGGAAAGTGCCGTGACCAAGGTATCCACCAGCCAGGA
AATGGTGTCTGAGATGCCGGTGTAGGCGGGAGGGATTTGGATTTCCTAGGCCAGCTCACAACTG
TGCAGCTTCAGGCACAGCTGGATGCAGGAGCTCGGAGATGGCTTTTATTCTTCGTTCAATAAAC
ATTCATTGTGCACTTGCTTGTGCAAAACCCTGATATAAAGGTGACAGTGGCTGGAGCCAATTCC
TTCCCCAGGAGGTAGCACATTACAGAGGGAGACAGATATGGAAACAGTTGAAGGGATACGGACT
ATGTCAAGGGTGGGATGTTCTACAGAATCCAAAGAGGGTGCTGGGGACACTGAGTGCCTGCTGT
ACAAACCGGGACCTGAGTTTGCGCCCCATCTCCTACACAAAAGCTGGGTATGGCGATACACCTT
TAACCCCAGCACGGAGGGAATAGGTGGACCCCAGAGGTTCTCTGGACGAGTGGTCTAGCCCAAT
AAACAAACTCCAGTCAGAGAGCCTGTCTCAAGAAATAGAGTGGAGCCAGGCATGGTGGTGAGAA
CTTTAATTTCAGCATTTGGGAGGCAGAGCCTGCAGATCTGTTTTAGGCTATCGGGATCTACATA
GTGAGATCCAGGTAGAGAGTACTAGATGTCGGGTAGGCTAGCACCTTGAAAAATGGTAATGACT
GAGCCAAAACCCAACTAATGGAGAGAGCATCCATGCTTAAGTCTGGGGAACTGTTCCAAGCAGA
CGGAGCAAACGCAGAGGCCTTGCTCTGGGGTACCTCTTCCAAGAAGCCCTCCCTGATTGCATCC
CTCCCAGACACAAGGGCTCATCTCTTCAACACAAATGCTTCAGAAAAATCCCAAGTCCCCTAAA
AGTGAGAGATGAACTCACTCCATCTTTTATATTTTTAGTTTATATCTATTTATTGCCTGTGTCT
GGAAGCACGAAGGGAGTGGGGTAGAGGGGTGGTTAGAGGACAACGCCTTCCATCATGTGGGTCC
TCGGGATTGAACTCAGGGTGTCAGGCTTGGCTGTAAGCATCTTTGAGCCTGCTGAGCCATCCCA
CCAGCCCTAAACTCCTCAGTCTTAGAAAGTACTGTATTTCCTCTGTCCACACACCAATTTATTT
CAGCTGGTCTCTGGGCCTGTTGATATTGCTGATGCCTTTTTGTTAATTTATTTTCGAGGATTTT
TTTTAAACGATTTTTATTTTTAAAAGTTCCTATGGCTATATATTGTACATCGAGAGATCTCCAC
CCTTACCCCAGGTTTGCAGATCTGTAACACCTATGGCATACTGTGTCCAGCCAACTCTCCTCCA
CAGATCCCTACAGCCTGGCTTTGGTCTTGGTTTTCTTTCTTGATTTTTTTTTTAAGATAGGGTC
TCATAGAGCCCATGATGGCTTTGAACTCACTATGTAGCTAAGGATGGCCTTTAGCATCTCCTGG
GTGCTGGGATTATAGTCCTGCATCACAACACCTGGTTTATGGAGTGCTGGGGATCAAACACAGG
GCTTCATCCATGCTAGGCAAATGCTCTATCAACTGGAGTTCCTCACCATGGCATTCTAGGCAGC
TGTCCTTGTACTGAGCTCCATCCCAAACTGTACTTGAACAATGTATACACCTGTCTGTGTGAAA
AGTTCAAAGAATTTTTGGTTAATTTACTGGACCAGAGAGCCTCTTTAGAAAGCCTTTTGAAAAA
AATTTTTTTAAAAGTAAACTTTGAGAGTTTCTGTTTAATTCTTTAGCCTTAAAAAATGAAGGAG
AAATTTCATGAGATCTTCTAAATGTATTTCTGTGCAATTATACATAAAATCACTTGATGTTAAA
AA

hide sequence

RefSeq Acc Id:

XM_006228353 ⟹ XP_006228415

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,058,557 - 86,071,185 (-)	NCBI
mRatBN7.2	1	76,930,381 - 76,942,997 (-)	NCBI
Rnor_6.0	1	78,165,155 - 78,180,781 (-)	NCBI
Rnor_5.0	1	79,431,191 - 79,448,689 (-)	NCBI

Sequence:

show sequence

GCCTCTGTCTCCAGAGTGCTGTGATCAAAGGTGTGCGCCACCACTGCATGACAGGTCTTGGCAT
TTTATGTTCTCTGGAAACCTCAGGCCCTGGACTCAGCTTCTTGAACTTTTGAGAAGGGGTAATT
GTGGGCTATGCTCCTCACATTTGAGGAAGGAAAGCTCTTTAAGAGTCTGAGGCTGGCAGGAATG
CGTGGCGGAGAGCAGCACAGCGGGTCAGGAGTGGGTCAGCAGGCTGCTGGTACTTACTCTGGAT
CCTTAGAGGCACTTTAGTGCCAAAGGTGTCTGGGGCCAGGATGCTGAACGACACCACCAGCAAG
GATTATGAGTATGAGTATGATCAGGAACAGTATAGTGACCTTCTGAACGTCCCCGTAGACTGCC
CAGCTGGCAACTGCTTCTCTAATGATGCCTACCTCATAGTCCTGCTTGGCCTGTATTCAGTCAT
CTTCCTGGTGGGTGTGCCAGGCAACACCCTGTTGGCGTGGGTGACCTGGAAAGAGTCTCGCCAC
AGGCTCGGGGCCTCTTGGTTCCTGCACTTGACCATGGCGGACTTGCTTTGCTGTGTGTCTCTGC
CCTTCCTGGCTGTGCCCATCGCCCAAAAGGGCCACTGGCCATACGGGACAGCAGGCTGCTGGCT
GTTGTCCTCCATCACCGTTCTGTCTATGTATGCCAGTGTGCTGCTCCTGACGGGCCTCAGTGGC
GACCTCTTCCTATTGGCTTTCAGGCCCTCCTGGAAGAATGCAGATCAACGAACATGTGGGGTGC
GTGTGGTCCAGGTCTCCTCCTGGATGCTGGCCCTGTTGCTGACTGTGCCTGGTGCTGTCTATCG
TAAGCTGCTTCAGGAGCACTATCCTCCCCGGCTTGTGTGTGGCACAAACTATGGGGGATCGGTC
ACCGCGGAAGTTACCATCACCACTGTTCGATTCCTCTTTGGCTTCCTGGTGCCATTGGTGTTCA
TGGCCAGTTGCCACGGCATCCTCCAACGGCAGATGGCTCGCCGCCACTGGCCCCTGGGCACAGC
TGTTGTGGTGGGGTTTTTCATTTGCTGGACCCCTTTTCACCTCCTGCGGGTCATCATTGCAGTG
GCTTCTTCACACTCCCCGCTCCTTGCCTGGGCCCTGGAGGCTGAGCCTTTGGTTACGGGCCTGG
CCCTTGCTCACAGTGCTCTCAATCCTATTATGTTTTTGTATTTCGGAAGAAAACAACTCTGCAA
GTCACTCCAGGCTGCATGTCACTGGGCCCTGAGGGATCTACAGGATGAGGAGGAAAGTGCCGTG
ACCAAGGTATCCACCAGCCAGGAAATGGTGTCTGAGATGCCGGTGTAGGCGGGAGGGATTTGGA
TTTCCTAGGCCAGCTCACAACTGTGCAGCTTCAGGCACAGCTGGATGCAGGAGCTCGGAGATGG
CTTTTATTCTTCGTTCAATAAACATTCATTGTGCACTTGCTTGTGCAAAACCCTGATATAAAGG
TGACAGTGGCTGGAGCCAATTCCTTCCCCAGGAGGTAGCACATTACAGAGGGAGACAGATATGG
AAACAGTTGAAGGGATACGGACTATGTCAAGGGTGGGATGTTCTACAGAATCCAAAGAGGGTGC
TGGGGACACTGAGTGCCTGCTGTACAAACCGGGACCTGAGTTTGCGCCCCATCTCCTACACAAA
AGCTGGGTATGGCGATACACCTTTAACCCCAGCACGGAGGGAATAGGTGGACCCCAGAGGTTCT
CTGGACGAGTGGTCTAGCCCAATAAACAAACTCCAGTCAGAGAGCCTGTCTCAAGAAATAGAGT
GGAGCCAGGCATGGTGGTGAGAACTTTAATTTCAGCATTTGGGAGGCAGAGCCTGCAGATCTGT
TTTAGGCTATCGGGATCTACATAGTGAGATCCAGGTAGAGAGTACTAGATGTCGGGTAGGCTAG
CACCTTGAAAAATGGTAATGACTGAGCCAAAACCCAACTAATGGAGAGAGCATCCATGCTTAAG
TCTGGGGAACTGTTCCAAGCAGACGGAGCAAACGCAGAGGCCTTGCTCTGGGGTACCTCTTCCA
AGAAGCCCTCCCTGATTGCATCCCTCCCAGACACAAGGGCTCATCTCTTCAACACAAATGCTTC
AGAAAAATCCCAAGTCCCCTAAAAGTGAGAGATGAACTCACTCCATCTTTTATATTTTTAGTTT
ATATCTATTTATTGCCTGTGTCTGGAAGCACGAAGGGAGTGGGGTAGAGGGGTGGTTAGAGGAC
AACGCCTTCCATCATGTGGGTCCTCGGGATTGAACTCAGGGTGTCAGGCTTGGCTGTAAGCATC
TTTGAGCCTGCTGAGCCATCCCACCAGCCCTAAACTCCTCAGTCTTAGAAAGTACTGTATTTCC
TCTGTCCACACACCAATTTATTTCAGCTGGTCTCTGGGCCTGTTGATATTGCTGATGCCTTTTT
GTTAATTTATTTTCGAGGATTTTTTTTAAACGATTTTTATTTTTAAAAGTTCCTATGGCTATAT
ATTGTACATCGAGAGATCTCCACCCTTACCCCAGGTTTGCAGATCTGTAACACCTATGGCATAC
TGTGTCCAGCCAACTCTCCTCCACAGATCCCTACAGCCTGGCTTTGGTCTTGGTTTTCTTTCTT
GATTTTTTTTTTAAGATAGGGTCTCATAGAGCCCATGATGGCTTTGAACTCACTATGTAGCTAA
GGATGGCCTTTAGCATCTCCTGGGTGCTGGGATTATAGTCCTGCATCACAACACCTGGTTTATG
GAGTGCTGGGGATCAAACACAGGGCTTCATCCATGCTAGGCAAATGCTCTATCAACTGGAGTTC
CTCACCATGGCATTCTAGGCAGCTGTCCTTGTACTGAGCTCCATCCCAAACTGTACTTGAACAA
TGTATACACCTGTCTGTGTGAAAAGTTCAAAGAATTTTTGGTTAATTTACTGGACCAGAGAGCC
TCTTTAGAAAGCCTTTTGAAAAAAATTTTTTTAAAAGTAAACTTTGAGAGTTTCTGTTTAATTC
TTTAGCCTTAAAAAATGAAGGAGAAATTTCATGAGATCTTCTAAATGTATTTCTGTGCAATTAT
ACATAAAATCACTTGATGTTAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001003710	(Get FASTA)	NCBI Sequence Viewer
	XP_006228414	(Get FASTA)	NCBI Sequence Viewer
	XP_006228415	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAT12287	(Get FASTA)	NCBI Sequence Viewer
	AAU89282	(Get FASTA)	NCBI Sequence Viewer
	EDM08333	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067721.2
	ENSRNOP00000081314.1
	ENSRNOP00000088875.1
	ENSRNOP00055023162
	ENSRNOP00060029474
	ENSRNOP00065047969
GenBank Protein	Q695P6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001003710 ⟸ NM_001003710

- UniProtKB:

Q695P6 (UniProtKB/Swiss-Prot), A6J8A1 (UniProtKB/TrEMBL), Q5XPY4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLNDTTSKDYEYEYDQEQYSDLLNVPVDCPAGNCFSNDAYLIVLLGLYSVIFLVGVPGNTLLAW
VTWKESRHRLGASWFLHLTMADLLCCVSLPFLAVPIAQKGHWPYGTAGCWLLSSITVLSMYASV
LLLTGLSGDLFLLAFRPSWKNADQRTCGVRVVQVSSWMLALLLTVPGAVYRKLLQEHYPPRLVC
GTNYGGSVTAEVTITTVRFLFGFLVPLVFMASCHGILQRQMARRHWPLGTAVVVGFFICWTPFH
LLRVIIAVAFSHSPLLAWALEAEPLVTGLALAHSALNPIMFLNFGRKQLCKSLQAACHWALRDL
QDEEESAVTKVSTSQEMVSEMPV

hide sequence

RefSeq Acc Id:	XP_006228414 ⟸ XM_006228352
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QZB1 (UniProtKB/TrEMBL), Q5XPY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNYEGLGDGSVSKVFAIQTEGHDFQPQDVDMSSTELRTVSGARMLNDTTSKDYEYEYDQEQYSD LLNVPVDCPAGNCFSNDAYLIVLLGLYSVIFLVGVPGNTLLAWVTWKESRHRLGASWFLHLTMA DLLCCVSLPFLAVPIAQKGHWPYGTAGCWLLSSITVLSMYASVLLLTGLSGDLFLLAFRPSWKN ADQRTCGVRVVQVSSWMLALLLTVPGAVYRKLLQEHYPPRLVCGTNYGGSVTAEVTITTVRFLF GFLVPLVFMASCHGILQRQMARRHWPLGTAVVVGFFICWTPFHLLRVIIAVASSHSPLLAWALE AEPLVTGLALAHSALNPIMFLYFGRKQLCKSLQAACHWALRDLQDEEESAVTKVSTSQEMVSEM PV hide sequence

RefSeq Acc Id:	XP_006228415 ⟸ XM_006228353
- Peptide Label:	isoform X2
- UniProtKB:	Q695P6 (UniProtKB/Swiss-Prot), A6J8A1 (UniProtKB/TrEMBL), Q5XPY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLNDTTSKDYEYEYDQEQYSDLLNVPVDCPAGNCFSNDAYLIVLLGLYSVIFLVGVPGNTLLAW VTWKESRHRLGASWFLHLTMADLLCCVSLPFLAVPIAQKGHWPYGTAGCWLLSSITVLSMYASV LLLTGLSGDLFLLAFRPSWKNADQRTCGVRVVQVSSWMLALLLTVPGAVYRKLLQEHYPPRLVC GTNYGGSVTAEVTITTVRFLFGFLVPLVFMASCHGILQRQMARRHWPLGTAVVVGFFICWTPFH LLRVIIAVASSHSPLLAWALEAEPLVTGLALAHSALNPIMFLYFGRKQLCKSLQAACHWALRDL QDEEESAVTKVSTSQEMVSEMPV hide sequence

Ensembl Acc Id:

ENSRNOP00000067721 ⟸ ENSRNOT00000071576

Ensembl Acc Id:

ENSRNOP00000088875 ⟸ ENSRNOT00000099386

Ensembl Acc Id:

ENSRNOP00000081314 ⟸ ENSRNOT00000102131

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q695P6-F1-model_v2	AlphaFold	Q695P6	1-343	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303027	AgrOrtholog
BioCyc Gene	G2FUF-60618	BioCyc
Ensembl Genes	ENSRNOG00000049028	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055016930	UniProtKB/Swiss-Prot
	ENSRNOG00060020666	UniProtKB/Swiss-Prot
	ENSRNOG00065033945	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000071576.3	UniProtKB/TrEMBL
	ENSRNOT00000099386.1	UniProtKB/TrEMBL
	ENSRNOT00000102131.1	UniProtKB/Swiss-Prot
	ENSRNOT00055028753	UniProtKB/Swiss-Prot
	ENSRNOT00060035814	UniProtKB/Swiss-Prot
	ENSRNOT00065058292	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Anphylx_rcpt	UniProtKB/TrEMBL
	Formyl_rcpt-rel	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:445269	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	445269	ENTREZGENE
PANTHER	C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1	UniProtKB/TrEMBL
	PTHR24225	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR24225:SF1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	C5ar2	PhenoGen
PRINTS	ANPHYLATOXNR	UniProtKB/TrEMBL
	C5ANPHYLTXNR	UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000049028	RatGTEx
	ENSRNOG00055016930	RatGTEx
	ENSRNOG00060020666	RatGTEx
	ENSRNOG00065033945	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6AAK5_RAT	UniProtKB/TrEMBL
	A0A8L2QZB1	ENTREZGENE, UniProtKB/TrEMBL
	A6J8A1	ENTREZGENE, UniProtKB/TrEMBL
	C5AR2_RAT	UniProtKB/Swiss-Prot
	Q5XPY4	ENTREZGENE, UniProtKB/TrEMBL
	Q695P6	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-04-29	C5ar2	complement C5a receptor 2	C5ar2	complement component 5a receptor 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-01	C5ar2	complement component 5a receptor 2	Gpr77	G protein-coupled receptor 77	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-02-14	Gpr77	G protein-coupled receptor 77			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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