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Gene: C5ar2 (complement component 5a receptor 2) Rattus norvegicus
Symbol: C5ar2
Name: complement component 5a receptor 2
Description: Predicted to have G protein-coupled receptor activity and complement component C5a receptor activity. Predicted to be involved in several processes, including negative regulation of neutrophil chemotaxis; negative regulation of tumor necrosis factor production; and regulation of cytokine secretion. Predicted to localize to the apical part of cell and basal plasma membrane. Orthologous to human C5AR2 (complement component 5a receptor 2); INTERACTS WITH (R)-noradrenaline; acrylamide; bisphenol A.
Type: protein-coding
Also known as: C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5A receptor beta; C5L2; complement 5A receptor beta; G protein-coupled receptor 77; G-protein coupled receptor 77; Gpr77
Homo sapiens (human) : C5AR2 (complement component 5a receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : C5ar2 (complement component 5a receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C5ar2 (complement component 5a receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : C5AR2 (complement component 5a receptor 2)
Canis lupus familiaris (dog) : C5AR2 (complement component 5a receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C5ar2 (complement component 5a receptor 2)
Sus scrofa (pig) : C5AR2 (complement component 5a receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0178,165,155 - 78,183,426 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0179,431,191 - 79,448,689 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera171,422,103 - 71,432,305 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on C5ar2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303027
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.