Efnb1 (ephrin B1) - Rat Genome Database

Name: Efnb1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Efnb1 (ephrin B1) Rattus norvegicus

Analyze

Symbol:

Efnb1

Name:

ephrin B1

RGD ID:

2540

Description:

Predicted to have ephrin receptor binding activity. Involved in presynapse assembly. Localizes to glutamatergic synapse and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome and dysostosis. Orthologous to human EFNB1 (ephrin B1); PARTICIPATES IN altered ephrin - ephrin receptor bidirectional signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; ephrin-B1; LERK-2; LERK2

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EFNB1 (ephrin B1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Efnb1 (ephrin B1)	HGNC	EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Efnb1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EFNB1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EFNB1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Efnb1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EFNB1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	EFNB1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Efnb1 (ephrin B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Efnb1 (ephrin B1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Homo sapiens (human):	EFNB1 (ephrin B1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	efnb1 (ephrin-B1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	efn-2	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ephrin	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	64,257,351 - 64,270,158 (+)	NCBI
Rnor_6.0 Ensembl	X	68,891,227 - 68,904,038 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	X	68,891,227 - 68,904,034 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	X	69,764,314 - 69,777,121 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	87,163,176 - 87,175,982 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	X	87,236,467 - 87,249,273 (+)	NCBI
Celera	X	64,624,957 - 64,637,749 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

craniofrontonasal syndrome (ISO)

craniosynostosis (ISO)

dysostosis (ISO)

Frontonasal Dysplasia (ISO)

genetic disease (ISO)

Hypertelorism (ISO)

Inflammation (ISO)

obesity (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chrysene (ISO)

cisplatin (ISO)

cocaine (EXP)

dexamethasone (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

endosulfan (EXP)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

indometacin (ISO)

isobutanol (ISO)

leflunomide (ISO)

maneb (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methamphetamine (EXP)

methotrexate (ISO)

nitrofen (EXP)

paraquat (ISO)

pentachlorophenol (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

propiconazole (ISO)

SCH 23390 (EXP)

sodium arsenite (ISO)

Soman (EXP)

tetraphene (ISO)

trichloroethene (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon guidance (IBA,IEA,ISO,TAS)

embryonic pattern specification (IEA,ISO)

ephrin receptor signaling pathway (IBA,IEA,TAS)

nervous system development (IMP)

neural crest cell migration (IEA,ISO)

positive regulation of T cell proliferation (IEA,ISO)

presynapse assembly (IDA,IMP)

T cell costimulation (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

glutamatergic synapse (IDA,IMP)

integral component of membrane (IEA)

integral component of presynaptic membrane (IDA)

membrane raft (IEA,ISO)

nucleus (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

synapse (IDA)

Molecular Function

ephrin receptor binding (IBA,IEA,ISO,TAS)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

altered ephrin - ephrin receptor bidirectional signaling pathway (ISS)

ephrin - ephrin receptor bidirectional signaling axis (ISO,TAS)

References

References - curated


1.	Fletcher FA, etal., Oncogene 1994 Nov;9(11):3241-7.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	McClelland AC, etal., Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20487-92. doi: 10.1073/pnas.0811862106. Epub 2009 Nov 13.
5.	MGD data from the GO Consortium
6.	Moreno-Flores MT, etal., Mol Cell Neurosci 2002 Jul;20(3):429-46.
7.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline
9.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10.	RGD automated data pipeline
11.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	RGD automated import pipeline for gene-chemical interactions
13.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.	Surawska H, etal., Cytokine Growth Factor Rev 2004 Dec;15(6):419-33.
15.	Torres R, etal., Neuron. 1998 Dec;21(6):1453-63.
16.	Wieland I, etal., Am J Hum Genet. 2004 Jun;74(6):1209-15. Epub 2004 Apr 29.

Additional References at PubMed

PMID:10197531	PMID:10558890	PMID:11731465	PMID:14988728	PMID:15037550	PMID:15502157	PMID:15599401	PMID:16052680	PMID:17667985	PMID:18321739	PMID:18448254	PMID:19056867
PMID:19515908	PMID:20633976	PMID:23376485	PMID:23881165	PMID:25922200	PMID:29602834

Genomics

Comparative Map Data

Efnb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	64,257,351 - 64,270,158 (+)	NCBI
Rnor_6.0 Ensembl	X	68,891,227 - 68,904,038 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	X	68,891,227 - 68,904,034 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	X	69,764,314 - 69,777,121 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	87,163,176 - 87,175,982 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	X	87,236,467 - 87,249,273 (+)	NCBI
Celera	X	64,624,957 - 64,637,749 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

EFNB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	X	68,829,021 - 68,842,160 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	X	68,829,021 - 68,842,160 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	X	68,048,864 - 68,062,003 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	67,965,556 - 67,978,728 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	X	67,831,851 - 67,845,023	NCBI
Celera	X	68,401,732 - 68,414,899 (+)	NCBI
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	61,874,538 - 61,887,692 (+)	NCBI		HuRef
CHM1_1	X	67,941,979 - 67,955,149 (+)	NCBI		CHM1_1

Efnb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	98,179,667 - 98,192,628 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	X	98,179,736 - 98,192,597 (+)	Ensembl
GRCm38	X	99,136,061 - 99,149,022 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	99,136,130 - 99,148,991 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	96,331,469 - 96,344,330 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	X	95,338,849 - 95,351,710 (+)	NCBI			mm8
Celera	X	86,077,235 - 86,090,145 (+)	NCBI		Celera
Cytogenetic Map	X	C3	NCBI
cM Map	X	43.22	NCBI

Efnb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955475	8,360,465 - 8,373,578 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955475	8,360,504 - 8,372,431 (+)	NCBI	ChiLan1.0	ChiLan1.0

EFNB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	X	68,139,078 - 68,152,127 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	68,139,078 - 68,152,131 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	X	58,075,744 - 58,088,838 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

EFNB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	53,292,407 - 53,303,824 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	53,292,565 - 53,304,600 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	44,117,929 - 44,130,926 (+)	NCBI
ROS_Cfam_1.0	X	54,257,764 - 54,270,762 (+)	NCBI
UMICH_Zoey_3.1	X	52,225,889 - 52,238,885 (+)	NCBI
UNSW_CanFamBas_1.0	X	53,554,687 - 53,567,686 (+)	NCBI
UU_Cfam_GSD_1.0	X	53,478,390 - 53,491,387 (+)	NCBI

Efnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	48,786,595 - 48,799,574 (-)	NCBI
SpeTri2.0	NW_004936777	434,729 - 447,778 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EFNB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	54,948,342 - 54,973,629 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	54,947,339 - 54,961,403 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	62,073,418 - 62,080,778 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EFNB1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	58,668,572 - 58,681,583 (+)	NCBI
ChlSab1.1 Ensembl	X	58,668,581 - 58,681,855 (+)	Ensembl

Efnb1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624891	1,394,948 - 1,407,898 (-)	NCBI

Position Markers

AA964352

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	64,269,831 - 64,270,039 (+)	MAPPER
Rnor_6.0	X	68,903,708 - 68,903,915	NCBI	Rnor6.0
Rnor_5.0	X	69,776,795 - 69,777,002	UniSTS	Rnor5.0
RGSC_v3.4	X	87,175,656 - 87,175,863	UniSTS	RGSC3.4
Celera	X	64,637,423 - 64,637,630	UniSTS
Cytogenetic Map	X	q22.1	UniSTS

EFNB1_609

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	64,268,788 - 64,269,460 (+)	MAPPER
Rnor_6.0	X	68,902,665 - 68,903,336	NCBI	Rnor6.0
Rnor_5.0	X	69,775,752 - 69,776,423	UniSTS	Rnor5.0
RGSC_v3.4	X	87,174,613 - 87,175,284	UniSTS	RGSC3.4
Celera	X	64,636,394 - 64,637,065	UniSTS
Cytogenetic Map	X	q22.1	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	15688119	127888215	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	44320616	158345622	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	44557974	120045269	Rat
70221	Bp56	Blood pressure QTL 56	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	61398097	70352120	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	457
Count of miRNA genes:	238
Interacting mature miRNAs:	305
Transcripts:	ENSRNOT00000009635
Prediction methods:	Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	33	20	12		12			53	35	36	11
Low		10	37	29	19	29	8	11	21		5		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC061744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U07560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000009635 ⟹ ENSRNOP00000009635

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	X	68,891,227 - 68,904,038 (+)	Ensembl

RefSeq Acc Id:

NM_017089 ⟹ NP_058785

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	64,257,351 - 64,270,158 (+)	NCBI
Rnor_6.0	X	68,891,227 - 68,904,034 (+)	NCBI
Rnor_5.0	X	69,764,314 - 69,777,121 (+)	NCBI
RGSC_v3.4	X	87,163,176 - 87,175,982 (+)	RGD
Celera	X	64,624,957 - 64,637,749 (+)	RGD

Sequence:

show sequence

CGCTGGACAGCAGTGGGGGGTGTGTGAGATTCGCACTGACTGCCGACACTCCGGCTCAATCGCC
GGGGATTAAGGACTTGGCGACCCGGCTGCCGGGCTGCCCGGCCGAGGCTTCAGAGGCGCAAATT
GATGGGACTGATTTGCTCAGTAGGGCCGTACTAGTCTTTTAAGTATACTGAGAAGGGCCGGTGC
TAAAGTAGAAGCTGTCGTGGGACGCGCCGGCGCGGAGTCCCACAGTGGCCCGGAGGAACGGAGT
CCGTGCTAGGGGGACCCAGTCCGGAGCCTGGGGACCGAGCTCGCATTGTTGGGAGACAACCCGC
CTCTTCTTCCCAGAGGCGTCAATCCCAGGACGGTCGAGGCGTCGGGGCAACCACTGAGCGCTCT
GCAGAGAGACCCGGTCGGGGAGAGGACTCGCAGTCTCAAACAGTCTGGGAGAGCCGATCGGAAT
CCGGCGGGATCACTCGGGGGCGGCGAGCCCCCGTCGCGCCTCGTGCGGCGGAGAGGCCAGGGGA
GAAAGTCCTCCGAGGCAGCAGTCCATGCGCGGGTTGGGGACGCCTGCCCAGTGAATCCTCCTGG
CCAGCCGGGCGCAGGAGAGCGACCCCGAGGCCGGCGGGAGGAGAGTGCTTCAAGGCCGGCGGCT
GCGGAGGATGGGCGCCTAAGTGGCTCCGAGCGCTGCGCGGCAAGGGCAGGCGAGGCGAGCTTTG
CTGAGGAGGTGCTAGGGGATCCTGAAGTGCATCCTGCCCCCGGGAAAATGGCCCGGCCTGGGCA
GCGTTGGCTCAGCAAGTGGCTTGTGGCTATGGTCGTGCTGACGCTGTGCCGGCTTGCCACGCCG
TTGGCCAAGAACCTGGAGCCCGTGTCCTGGAGCTCTCTTAACCCTAAGTTCCTAAGTGGGAAGG
GCTTGGTGATCTACCCGAAGATTGGAGATAAGCTGGACATCATCTGCCCCCGAGCAGAAGCAGG
ACGGCCCTACGAGTACTACAAGCTGTACCTGGTGCGGCCGGAGCAGGCAGCTGCTTGCAGCACT
GTGCTTGATCCCAATGTACTGGTCACTTGCAACAAGCCACAGCAGGAAATCCGCTTTACCATCA
AGTTCCAGGAGTTCAGCCCCAACTACATGGGCCTGGAATTCAAAAAGTACCATGATTACTACAT
TACATCAACATCCAATGGGAGCTTGGAAGGGCTGGAGAACCGAGAGGGAGGTGTGTGCCGTACA
CGCACTATGAAGATTGTTATGAAGGTTGGGCAAGATCCAAATGCCGTAACGCCTGAGCAGTTGA
CTACCAGCCGGCCAAGCAAAGAGTCAGACAACACTGTCAAGACAGCCACACAGGCTCCTGGTCG
GGGGTCCCAGGGGGACTCTGATGGCAAGCATGAGACTGTGAACCAGCAAGAGAAGAGTGGCCCA
GGTGCAGGTGGTAGTGGCAGCGGGGACACCGACAGCTTCTTTAACTCCAAGGTAGCATTGTTCG
CAGCTGTAGGTGCTGGCTGCGTCATCTTCCTGCTCATTATCATCTTTTTGACAGTCCTACTACT
CAAGCTCCGCAAGCGACATCGCAAGCATACACAGCAGCGGGCGGCTGCCCTCTCGCTCAGTACC
CTAGCCAGCCCCAAAGGGGGTAGTGGTACAGCGGGCACTGAGCCCAGCGACATCATCATCCCCT
TACGGACTACAGAGAACAACTACTGCCCCCACTATGAGAAGGTGAGTGGGGACTACGGGCATCC
TGTCTACATCGTCCAGGAGATGCCACCTCAGAGCCCGGCGAACATCTACTACAAGGTCTGAGGG
CCCAGCATGGCCTCAGGCTCCACAGGACACATGGCCTGGATTGGCCTCTCTTTTCTCCCCCACA
CCCCTCCCCTTGCCAGCTGTGCCCACCTTTGTATTTAGTTTTGTAGTTTCTTGGCTTTTATAAT
CCCCCTTTTTTCCTGCCCCTTGGGCTTCGGAGGGGGGTGCTTGTGCCCCCAATCCCCATGCTCT
TGTGCCTTCCCCCTCTGGCCAGGCCTCTGGGCTCTGTGGGGGTGCCCTTTCTTGGAGGGCAGGG
TTGGACACTGATGGACTGCAGGCAGGGAGATAGCCCCCTGGCCCTGCCCCCTCCTCATCCCTTC
ACCCATCCCCAGGACTGCTTGTCCACTATCATCACTGTTTTTAATGCTTTTGTGTTGATTTTTT
TAGCTGTCAACTCATTTTCATCTGTTTTTTTTATTTTTGAGAAAAAAATGGGAAAATGTACAAG
GCAGCCCCTCCCCAGGCTTTCTGAGCCTGGCCTGACCCAGTATGAGAGGGCCTGGGGCAGGATG
TGGCCAGCCAGGAAACATAGGATGGCATTTCTTTTATAGACTCCTCAGTAGTTCAGGGGAGTGG
GGGAGGGTAGGCCATGGCTATTTCTGCCTAGCAGGGAGAGGAGAGTGCCACCCTCCTTTTTGGA
CCCCCATGATACAATGCTGTTCCTAGCAGTGGGGTAGTGTCTACCACCCTTCTACCAAAAAAAA
ATCCCTTCCTTGTGGGATTCTTGGGCATCTCCTGCCTCCTTCACTCTCACGGTAATTAATGTCT
TAATTGGCTGTTGCCTGGGGAACAGGAGAGCTGCTGCAGGCAGATGACCTCATGGGGGGTGGAG
GGAGGTGAGGTGCCCAGGTGGCTATTTGCCCTGCAGAGCTGGGAGTTTCCCCCCACCACCCTGT
CTCTCTCCTTACCTTCGGCATCTTTGGCTCAAGGTGGAGATAGATGTAAGCGGTGTAAGGCCAG
ATGGCCTGCTCCTTCCCTGGGTTCTAGTACAAGTAAGCACACACACACCCCCACTCACTCAATA
TGGCTCCCACTGTCCCCCACCCCGCCCATAGTTTTGAGCAGGGGCCTGGAAAGAGGAAGAGGCT
GCTTGGGGCTGGGCCAGCCTGCAGTGCACTTTGACCCCAGCTCCTTGCCAGCACGGCTGCTAAC
AGACTGCCACTCAACTGCGCCTTGCAGGCACTCCCAGGGCTGCCATGGAAGGAGCTGGGCCTTA
CACCACCCACCTCCACACTGCCTCCTGGCCAGCTGCCCACCCCAGTGCCAGGTGGGAGAGGGAG
CAAAACAGCCAGCCCCTTCCAGGTGGCAGTCGGAAGGGATTTTTGTTTTTGATTCTGTTGCCAT
TTGTGTAAATACTAGTCTTTTTTGGAAGAAATAATGTAAAGATGTTTTGTATAAACTCTGAATT
ATTTTCTTGTTGCTTTTTTCTTAGAAAAAAATGAGAACTAAAAAAAAATTAACCACATGGAAAA
AAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_058785	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA53092	(Get FASTA)	NCBI Sequence Viewer
	AAH61744	(Get FASTA)	NCBI Sequence Viewer
	EDL95949	(Get FASTA)	NCBI Sequence Viewer
	EDL95950	(Get FASTA)	NCBI Sequence Viewer
	P52796	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_058785 ⟸ NM_017089
- Peptide Label:	precursor
- UniProtKB:	Q6P7B6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARPGQRWLSKWLVAMVVLTLCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIIC PRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNKPQQEIRFTIKFQEFSPNYMGLEFKK YHDYYITSTSNGSLEGLENREGGVCRTRTMKIVMKVGQDPNAVTPEQLTTSRPSKESDNTVKTA TQAPGRGSQGDSDGKHETVNQQEKSGPGAGGSGSGDTDSFFNSKVALFAAVGAGCVIFLLIIIF LTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVS GDYGHPVYIVQEMPPQSPANIYYKV hide sequence

RefSeq Acc Id:

ENSRNOP00000009635 ⟸ ENSRNOT00000009635

Protein Domains

Ephrin RBD

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701859

Promoter ID:

EPDNEW_R12383

Type:

initiation region

Name:

Efnb1_1

Description:

ephrin B1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	68,891,221 - 68,891,281	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2540	AgrOrtholog
Ensembl Genes	ENSRNOG00000006877	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000009635	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000009635	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.420	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5599058	IMAGE-MGC_LOAD
InterPro	Cupredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin-B_Ecto	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_RBD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25186	UniProtKB/TrEMBL
MGC_CLONE	MGC:72504	IMAGE-MGC_LOAD
NCBI Gene	25186	ENTREZGENE
PANTHER	PTHR11304	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Ephrin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Efnb1	PhenoGen
PRINTS	EPHRIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	EPHRIN_RBD_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EPHRIN_RBD_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49503	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	EFNB1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6P7B6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Efnb1	Ephrin B1			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in granule and Purkinje neurons	727396

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)