Gfi1b (growth factor independent 1B transcriptional repressor) - Rat Genome Database

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Gene: Gfi1b (growth factor independent 1B transcriptional repressor) Rattus norvegicus
Analyze
Symbol: Gfi1b
Name: growth factor independent 1B transcriptional repressor
RGD ID: 1311727
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of granulocyte differentiation; and regulation of erythrocyte differentiation. Predicted to be located in nuclear matrix; nucleoplasm; and plasma membrane. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gray platelet syndrome and platelet-type bleeding disorder 17. Orthologous to human GFI1B (growth factor independent 1B transcriptional repressor); INTERACTS WITH bisphenol A; cadmium dichloride; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: growth factor independent 1B; growth factor independent 1B transcription repressor; LOC311832; zinc finger protein Gfi-1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,338,213 - 32,350,963 (-)NCBIGRCr8
mRatBN7.2311,940,232 - 11,952,989 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,940,233 - 11,952,942 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,012,664 - 15,025,303 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,597,615 - 23,610,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,852,075 - 21,864,709 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,190,721 - 7,203,444 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,190,722 - 7,203,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,540,994 - 12,553,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,598,772 - 7,611,402 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,599,577 - 7,605,032 (-)NCBI
Celera36,721,072 - 6,733,683 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Growth factor-independent 1B gene (GFI1B) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rate. Elmaagacli AH, etal., Br J Haematol. 2007 Jan;136(2):212-9. Epub 2006 Dec 8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. A dominant-negative GFI1B mutation in the gray platelet syndrome. Monteferrario D, etal., N Engl J Med. 2014 Jan 16;370(3):245-53. doi: 10.1056/NEJMoa1308130. Epub 2013 Dec 10.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia. Vassen L, etal., Int J Hematol. 2009 May;89(4):422-30. doi: 10.1007/s12185-009-0286-5. Epub 2009 Apr 10.
Additional References at PubMed
PMID:9566867   PMID:12477932   PMID:12874834   PMID:15920471   PMID:17707228  


Genomics

Comparative Map Data
Gfi1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,338,213 - 32,350,963 (-)NCBIGRCr8
mRatBN7.2311,940,232 - 11,952,989 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,940,233 - 11,952,942 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,012,664 - 15,025,303 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,597,615 - 23,610,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,852,075 - 21,864,709 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,190,721 - 7,203,444 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,190,722 - 7,203,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,540,994 - 12,553,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,598,772 - 7,611,402 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,599,577 - 7,605,032 (-)NCBI
Celera36,721,072 - 6,733,683 (-)NCBICelera
Cytogenetic Map3p12NCBI
GFI1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389132,945,531 - 132,993,434 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9132,944,000 - 132,991,687 (+)EnsemblGRCh38hg38GRCh38
GRCh379135,820,918 - 135,867,074 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,843,919 - 134,856,903 (+)NCBINCBI36Build 36hg18NCBI36
Build 349132,883,651 - 132,896,636NCBI
Celera9106,395,838 - 106,408,823 (+)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,347,908 - 105,360,763 (+)NCBIHuRef
CHM1_19136,004,426 - 136,017,406 (+)NCBICHM1_1
T2T-CHM13v2.09145,157,346 - 145,209,367 (+)NCBIT2T-CHM13v2.0
Gfi1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,499,462 - 28,511,994 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,499,462 - 28,511,994 (-)EnsemblGRCm39 Ensembl
GRCm38228,609,450 - 28,621,982 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,609,450 - 28,621,982 (-)EnsemblGRCm38mm10GRCm38
MGSCv37228,464,970 - 28,477,502 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,431,466 - 28,443,953 (-)NCBIMGSCv36mm8
Celera228,313,956 - 28,326,488 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Gfi1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,277,981 - 2,281,515 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,273,267 - 2,281,850 (+)NCBIChiLan1.0ChiLan1.0
GFI1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,363,078 - 6,376,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,365,415 - 6,378,854 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,061,236 - 104,113,208 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,692,343 - 132,742,326 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,692,343 - 132,742,326 (+)Ensemblpanpan1.1panPan2
GFI1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,380,697 - 51,394,679 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,380,696 - 51,392,812 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,643,918 - 50,674,158 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,273,983 - 52,304,414 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,273,980 - 52,278,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,052,489 - 51,082,796 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,376,978 - 51,407,295 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,456,418 - 51,486,732 (-)NCBIUU_Cfam_GSD_1.0
Gfi1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,639,690 - 199,649,460 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,414,135 - 19,417,465 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648719,414,135 - 19,417,465 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFI1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,702,184 - 272,715,539 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,701,386 - 272,715,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,852,829 - 306,866,368 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GFI1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1125,145,194 - 5,158,659 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,145,844 - 5,150,274 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,500,764 - 10,505,862 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfi1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,446,028 - 3,454,818 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,446,028 - 3,454,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gfi1b
106 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:301
Count of miRNA genes:190
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000015236
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat

Markers in Region
RH143268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2311,940,304 - 11,940,419 (+)MAPPERmRatBN7.2
Rnor_6.037,190,794 - 7,190,908NCBIRnor6.0
Rnor_5.0312,541,067 - 12,541,181UniSTSRnor5.0
RGSC_v3.437,598,791 - 7,598,905UniSTSRGSC3.4
Celera36,721,091 - 6,721,205UniSTS
RH 3.4 Map321.9UniSTS
Cytogenetic Map3p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 18 72 72 15 72
Low 14 42 8 6 30 6 56 18 51 39
Below cutoff 7 59 90 37 12 37 11 78 70 67 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC129847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC158685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015236   ⟹   ENSRNOP00000015236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl311,940,233 - 11,952,942 (-)Ensembl
Rnor_6.0 Ensembl37,190,722 - 7,203,420 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078428   ⟹   ENSRNOP00000070622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl37,190,726 - 7,202,848 (-)Ensembl
RefSeq Acc Id: NM_001107823   ⟹   NP_001101293
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,267 - 32,350,901 (-)NCBI
mRatBN7.2311,940,286 - 11,952,927 (-)NCBI
Rnor_6.037,190,775 - 7,203,405 (-)NCBI
Rnor_5.0312,540,994 - 12,553,716 (-)NCBI
RGSC_v3.437,598,772 - 7,611,402 (-)RGD
Celera36,721,072 - 6,733,683 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233789   ⟹   XP_006233851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,963 (-)NCBI
mRatBN7.2311,940,232 - 11,952,988 (-)NCBI
Rnor_6.037,190,721 - 7,203,444 (-)NCBI
Rnor_5.0312,540,994 - 12,553,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105213   ⟹   XP_038961141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,951 (-)NCBI
mRatBN7.2311,940,232 - 11,952,986 (-)NCBI
RefSeq Acc Id: XM_039105214   ⟹   XP_038961142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,434 (-)NCBI
mRatBN7.2311,940,232 - 11,952,814 (-)NCBI
RefSeq Acc Id: XM_039105215   ⟹   XP_038961143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,945 (-)NCBI
mRatBN7.2311,940,232 - 11,952,984 (-)NCBI
RefSeq Acc Id: XM_039105216   ⟹   XP_038961144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,346,665 (-)NCBI
mRatBN7.2311,940,232 - 11,948,686 (-)NCBI
RefSeq Acc Id: XM_039105218   ⟹   XP_038961146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,963 (-)NCBI
mRatBN7.2311,940,232 - 11,952,989 (-)NCBI
RefSeq Acc Id: XM_039105219   ⟹   XP_038961147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,346,864 (-)NCBI
mRatBN7.2311,940,232 - 11,948,885 (-)NCBI
RefSeq Acc Id: XM_063283925   ⟹   XP_063139995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,790 (-)NCBI
RefSeq Acc Id: NP_001101293   ⟸   NM_001107823
- UniProtKB: B0BN50 (UniProtKB/TrEMBL),   D3ZHB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233851   ⟸   XM_006233789
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070622   ⟸   ENSRNOT00000078428
Ensembl Acc Id: ENSRNOP00000015236   ⟸   ENSRNOT00000015236
RefSeq Acc Id: XP_038961146   ⟸   XM_039105218
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961141   ⟸   XM_039105213
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961143   ⟸   XM_039105215
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961142   ⟸   XM_039105214
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961147   ⟸   XM_039105219
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961144   ⟸   XM_039105216
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139995   ⟸   XM_063283925
- Peptide Label: isoform X2
- UniProtKB: B0BN50 (UniProtKB/TrEMBL),   D3ZHB6 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BN50-F1-model_v2 AlphaFold B0BN50 1-330 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311727 AgrOrtholog
BioCyc Gene G2FUF-50274 BioCyc
Ensembl Genes ENSRNOG00000011353 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015236.6 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8374780 IMAGE-MGC_LOAD
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:311832 UniProtKB/TrEMBL
MGC_CLONE MGC:187699 IMAGE-MGC_LOAD
NCBI Gene 311832 ENTREZGENE
PANTHER FI01424P-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Gfi1b PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011353 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8J8XL46 ENTREZGENE, UniProtKB/TrEMBL
  B0BN50 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHB6 ENTREZGENE
UniProt Secondary D3ZHB6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Gfi1b  growth factor independent 1B transcriptional repressor  Gfi1b  growth factor independent 1B transcription repressor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Gfi1b  growth factor independent 1B transcription repressor  Gfi1b  growth factor independent 1B   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Gfi1b  growth factor independent 1B   Gfi1b_predicted  growth factor independent 1B (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gfi1b_predicted  growth factor independent 1B (predicted)      Symbol and Name status set to approved 70820 APPROVED