Tcaf2 (TRPM8 channel-associated factor 2) - Rat Genome Database

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Gene: Tcaf2 (TRPM8 channel-associated factor 2) Rattus norvegicus
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Symbol: Tcaf2
Name: TRPM8 channel-associated factor 2
RGD ID: 6487302
Description: Predicted to enable transmembrane transporter binding activity. Predicted to be involved in negative regulation of anion channel activity; positive regulation of cell migration; and positive regulation of protein targeting to membrane. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in cell junction. Predicted to be active in plasma membrane. Orthologous to human TCAF2 (TRPM8 channel associated factor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; paracetamol.
Type: protein-coding
Previously known as: LOC100912372; LOC100912416; protein FAM115C-like; TRPM8 channel-associated factor 2-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0471,177,974 - 71,196,286 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl471,206,876 - 71,229,575 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,970,128 - 135,988,378 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map4q23NCBI


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:24029230   PMID:25559186  


Genomics

Comparative Map Data
Tcaf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0471,177,974 - 71,196,286 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl471,206,876 - 71,229,575 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,970,128 - 135,988,378 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map4q23NCBI
TCAF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387143,620,974 - 143,730,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7143,620,952 - 143,730,410 (+)EnsemblGRCh38hg38GRCh38
GRCh377143,318,067 - 143,427,503 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367143,028,667 - 143,053,107 (+)NCBINCBI36hg18NCBI36
Celera7138,603,155 - 138,611,956 (-)NCBI
Celera7138,126,412 - 138,132,830 (+)NCBI
Cytogenetic Map7q35NCBI
HuRef7137,646,274 - 137,676,224 (+)NCBIHuRef
CHM1_17143,336,941 - 143,364,191 (+)NCBICHM1_1
CRA_TCAGchr7v27142,735,400 - 142,765,339 (+)NCBI
Tcaf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39642,599,950 - 42,622,134 (-)NCBIGRCm39mm39
GRCm39 Ensembl642,599,950 - 42,622,188 (-)Ensembl
GRCm38642,623,043 - 42,645,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl642,623,016 - 42,645,254 (-)EnsemblGRCm38mm10GRCm38
MGSCv37642,573,042 - 42,595,040 (-)NCBIGRCm37mm9NCBIm37
MGSCv36642,552,650 - 42,574,648 (-)NCBImm8
Celera642,568,956 - 42,590,991 (-)NCBICelera
Cytogenetic Map6B2.1NCBI
Tcaf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955491149,111 - 167,578 (-)NCBIChiLan1.0ChiLan1.0
TCAF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17148,101,028 - 148,128,916 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v07135,609,379 - 135,639,928 (-)NCBIMhudiblu_PPA_v0panPan3
TCAF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,109,869 - 6,132,436 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,097,329 - 7,121,443 (+)NCBI
ROS_Cfam_1.0165,961,988 - 5,986,095 (+)NCBI
UMICH_Zoey_3.1165,909,927 - 5,934,145 (+)NCBI
UNSW_CanFamBas_1.0165,760,372 - 5,784,463 (+)NCBI
UU_Cfam_GSD_1.0165,836,684 - 5,860,797 (+)NCBI
Tcaf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511811,880,117 - 11,901,589 (+)NCBI
SpeTri2.0NW_0049365271,001,197 - 1,022,232 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110257570
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1186,632,982 - 6,719,077 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TCAF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121112,519,588 - 112,547,673 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660729,286,663 - 9,315,585 (-)NCBIVero_WHO_p1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 26 10 19 10 30 27 11
Below cutoff 43 31 31 31 8 10 66 5 11 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003749736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000050392   ⟹   ENSRNOP00000050765
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl471,208,323 - 71,227,872 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076650   ⟹   ENSRNOP00000068235
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl471,206,876 - 71,229,575 (-)Ensembl
RefSeq Acc Id: XM_003749736   ⟹   XP_003749784
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0471,177,974 - 71,196,286 (-)NCBI
Rnor_5.04135,970,128 - 135,988,378 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6487302 AgrOrtholog
Ensembl Genes ENSRNOG00000030222 Ensembl
NCBI Gene Tcaf2 ENTREZGENE
PhenoGen Tcaf2 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-16 Tcaf2  TRPM8 channel-associated factor 2  LOC100912416  protein FAM115C-like  Data Merged 737654 APPROVED
2015-06-30 Tcaf2  TRPM8 channel-associated factor 2  LOC100912372  protein FAM115C-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100912372  protein FAM115C-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100912416  protein FAM115C-like      Symbol and Name status set to provisional 70820 PROVISIONAL