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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dnah12 | Rat | Spermatogenic Failure 100 | | ISO | DNAH12 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dnah12 | Rat | Spermatogenic Failure 100 | | ISO | DNAH12 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Identification of seven rat axonemal dynein heavy chain genes: expression during ciliated cell differentiation. | Andrews KL, etal., Mol Biol Cell 1996 Jan;7(1):71-9. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Dnah12 (Rattus norvegicus - Norway rat) |
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DNAH12 (Homo sapiens - human) |
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Dnah12 (Mus musculus - house mouse) |
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Dnah12 (Chinchilla lanigera - long-tailed chinchilla) |
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DNAH12 (Pan paniscus - bonobo/pygmy chimpanzee) |
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DNAH12 (Canis lupus familiaris - dog) |
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Dnah12 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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DNAH12 (Sus scrofa - pig) |
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DNAH12 (Chlorocebus sabaeus - green monkey) |
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Dnah12 (Heterocephalus glaber - naked mole-rat) |
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Variants in Dnah12
865 total Variants ![]() |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
D16Chm68 |
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D16Chm73 |
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D16Chm69 |
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D16Chm48 |
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D16Got124 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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16 | 7 | 29 | 155 | 57 | 57 | 26 | 60 | 26 | 6 | 242 | 112 | 9 | 136 | 81 | 90 | 31 | 9 | 9 |
Ensembl Acc Id: | ENSRNOT00000079215 ⟹ ENSRNOP00000074159 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000097079 ⟹ ENSRNOP00000087078 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000150257 ⟹ ENSRNOP00000110882 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000154560 ⟹ ENSRNOP00000112549 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000160611 ⟹ ENSRNOP00000103541 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001419553 ⟹ NP_001406482 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063275064 ⟹ XP_063131134 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063275065 ⟹ XP_063131135 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063275066 ⟹ XP_063131136 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063275067 ⟹ XP_063131137 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOP00000074159 ⟸ ENSRNOT00000079215 |
Ensembl Acc Id: | ENSRNOP00000087078 ⟸ ENSRNOT00000097079 |
RefSeq Acc Id: | NP_001406482 ⟸ NM_001419553 |
- UniProtKB: | A0A0G2K7D4 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063131134 ⟸ XM_063275064 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6KMJ8 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063131136 ⟸ XM_063275066 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A6KMJ8 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063131135 ⟸ XM_063275065 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A6KMJ8 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063131137 ⟸ XM_063275067 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A0A0G2K7D4 (UniProtKB/TrEMBL) |
Ensembl Acc Id: | ENSRNOP00000112549 ⟸ ENSRNOT00000154560 |
Ensembl Acc Id: | ENSRNOP00000110882 ⟸ ENSRNOT00000150257 |
Ensembl Acc Id: | ENSRNOP00000103541 ⟸ ENSRNOT00000160611 |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:619990 | AgrOrtholog |
BioCyc Gene | G2FUF-12250 | BioCyc |
Ensembl Genes | ENSRNOG00000059865 | Ensembl, ENTREZGENE |
Ensembl Transcript | ENSRNOT00000079215 | ENTREZGENE |
Gene3D-CATH | 1.10.287.2620 | UniProtKB/Swiss-Prot |
1.10.8.710 | UniProtKB/Swiss-Prot | |
1.10.8.720 | UniProtKB/Swiss-Prot | |
1.20.1270.280 | UniProtKB/Swiss-Prot | |
1.20.140.100 | UniProtKB/Swiss-Prot | |
1.20.58.1120 | UniProtKB/Swiss-Prot | |
1.20.920.30 | UniProtKB/Swiss-Prot | |
3.10.490.20 | UniProtKB/Swiss-Prot | |
3.20.180.20 | UniProtKB/Swiss-Prot | |
3.40.50.300 | UniProtKB/Swiss-Prot | |
InterPro | AAA+_ATPase | UniProtKB/Swiss-Prot |
AAA_6 | UniProtKB/Swiss-Prot | |
AAA_lid_11 | UniProtKB/Swiss-Prot | |
AAA_lid_11_sf | UniProtKB/Swiss-Prot | |
DHC_fam | UniProtKB/Swiss-Prot | |
DNAH3_AAA_lid_1 | UniProtKB/Swiss-Prot | |
Dynein_2_C | UniProtKB/Swiss-Prot | |
Dynein_2_N | UniProtKB/Swiss-Prot | |
Dynein_AAA1S | UniProtKB/Swiss-Prot | |
Dynein_AAA5_ext | UniProtKB/Swiss-Prot | |
Dynein_C | UniProtKB/Swiss-Prot | |
Dynein_C_barrel | UniProtKB/Swiss-Prot | |
Dynein_heavy_chain_D4_dom | UniProtKB/Swiss-Prot | |
Dynein_heavy_D6_P-loop | UniProtKB/Swiss-Prot | |
Dynein_heavy_dom-2 | UniProtKB/Swiss-Prot | |
P-loop_NTPase | UniProtKB/Swiss-Prot | |
NCBI Gene | Dnah12 | ENTREZGENE |
PANTHER | DYNEIN HEAVY CHAIN 2, AXONEMAL | UniProtKB/Swiss-Prot |
DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED | UniProtKB/Swiss-Prot | |
Pfam | AAA_6 | UniProtKB/Swiss-Prot |
AAA_7 | UniProtKB/Swiss-Prot | |
AAA_8 | UniProtKB/Swiss-Prot | |
AAA_lid_1 | UniProtKB/Swiss-Prot | |
AAA_lid_11 | UniProtKB/Swiss-Prot | |
DHC_N2 | UniProtKB/Swiss-Prot | |
Dynein_AAA_lid | UniProtKB/Swiss-Prot | |
Dynein_C | UniProtKB/Swiss-Prot | |
Dynein_heavy | UniProtKB/Swiss-Prot | |
PhenoGen | Dnah12 | PhenoGen |
RatGTEx | ENSRNOG00000059865 | RatGTEx |
SMART | AAA | UniProtKB/Swiss-Prot |
Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot |
UniProt | A0A0G2K7D4 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A750_RAT | UniProtKB/TrEMBL | |
A6KMJ8 | ENTREZGENE, UniProtKB/TrEMBL | |
DYH12_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2010-04-20 | Dnah12 | dynein, axonemal, heavy chain 12 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2009-01-20 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Bm259 | BM259 protein | Data merged from RGD:620941 | 737654 | APPROVED |
2005-01-20 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
2002-08-07 | Bm259 | BM259 protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2002-08-07 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_disease | gene expression is upregulated in stroke-resistant spontaneously hypertensive (SHR) rats | 631971 |
gene_expression | specifically expressed in trachea, testis, and brain | 632533 |