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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of catalytic activity
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Accession:GO:0043086 term browser browse the term
Definition:Any process that stops or reduces the activity of an enzyme.
Synonyms:exact_synonym: down regulation of enzyme activity;   downregulation of enzyme activity;   negative regulation of enzyme activity
 narrow_synonym: down regulation of metalloenzyme activity;   downregulation of metalloenzyme activity;   inhibition of enzyme activity;   inhibition of metalloenzyme activity;   negative regulation of metalloenzyme activity
 alt_id: GO:0048553


show annotations for term's descendants           Sort by:
negative regulation of catalytic activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl4 angiopoietin-like 4 TAS RGD PMID:15863837 RGD:1578348 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Apba3 amyloid beta precursor protein binding family A member 3 involved_in ISO (PMID:19726677) RGD PMID:19726677 NCBI chr 7:9,096,936...9,103,457
Ensembl chr 7:8,446,216...8,451,241 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO MGI:5014325 (PMID:27806294) RGD PMID:27806294 NCBI chr 1:215,160,764...215,172,540
Ensembl chr 1:205,733,872...205,743,421 		JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12609982)		 UniProt
RGD		 PMID:12609982 GO_REF:0000024 NCBI chr 7:56,566,765...56,604,653
Ensembl chr 7:54,680,900...54,718,993 		JBrowse link
G Cast calpastatin IDA RGD PMID:17429681 RGD:1626249 NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:21030595) RGD PMID:21030595 NCBI chr15:51,622,519...51,637,911
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO MGI:1933976 (PMID:17868323) RGD PMID:17868323 NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R IMP arylalkylamine N-acetyltransferase activity RGD PMID:15798208 RGD:9854643 NCBI chr 5:153,826,482...153,872,272
Ensembl chr 5:148,543,044...148,574,867 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:8950980) RGD PMID:8950980 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Nes nestin involved_in ISO (PMID:21185309) RGD PMID:21185309 NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Nosip nitric oxide synthase interacting protein involved_in ISO (PMID:11149895) RGD PMID:11149895 NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17573339)		 UniProt
RGD		 PMID:17573339 GO_REF:0000024 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 acts_upstream_of_or_within ISO (PMID:10903442) RGD PMID:10903442 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:27796300) RGD PMID:27796300 NCBI chr11:78,286,282...78,320,409
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within ISO (PMID:7836431) RGD PMID:7836431 NCBI chr 2:96,306,181...96,380,959
Ensembl chr 2:94,398,869...94,414,282 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A involved_in ISS
ISO		 GO_REF:0000024
(PMID:19245366)		 UniProt
RGD		 PMID:19245366 GO_REF:0000024 NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Renbp renin binding protein IDA RGD PMID:11726282 RGD:5132613 NCBI chr  X:156,812,785...156,821,860
Ensembl chr  X:151,661,458...151,670,516 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:10956412) RGD PMID:10956412 NCBI chr13:23,788,758...23,795,298
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:3903517)		 UniProt
RGD		 PMID:3903517 GO_REF:0000024 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16636500)		 UniProt
RGD		 PMID:16636500 GO_REF:0000024 NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:75,871,835...75,889,069 		JBrowse link
negative regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (PMID:24962568) RGD PMID:24962568 NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Akap5 A-kinase anchoring protein 5 involved_in IDA
ISO		 (PMID:20410303), (PMID:21771783)
PMID:22976297		 RGD PMID:20410303 PMID:21771783 PMID:20410303 PMID:22976297 RGD:7242424, RGD:13800547 NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP RGD PMID:19574217 RGD:6902943 NCBI chr 6:75,919,350...76,359,667
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Akap9 A-kinase anchoring protein 9 IMP RGD PMID:18772391 RGD:2313147 NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (PMID:2531656) RGD PMID:2531656 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IMP RGD PMID:15147298 RGD:2315493 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:10869375 RGD:632981 NCBI chr 3:187,569,174...187,575,263
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:8702617 RGD:1601497 NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Palm paralemmin acts_upstream_of_or_within ISO (PMID:16386234) RGD PMID:16386234 NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:9,886,643...9,912,555 		JBrowse link
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Hpn hepsin acts_upstream_of_or_within ISO MGI:3575149 (PMID:22912808) RGD PMID:22912808 NCBI chr 1:95,464,468...95,480,169
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:21689636) RGD PMID:21689636 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc27a4 solute carrier family 27 member 4 involved_in ISO (PMID:23407971) RGD PMID:23407971 NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in ISO (PMID:27179792) RGD PMID:27179792 NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within ISO (PMID:16641999) RGD PMID:16641999 NCBI chr 6:110,722,887...110,757,743
Ensembl chr 6:104,991,838...105,026,753 		JBrowse link
negative regulation of ATP citrate synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18656514) RGD PMID:18656514 NCBI chr 3:28,791,062...28,792,905 JBrowse link
negative regulation of beta-galactosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO (PMID:16549446) RGD PMID:16549446 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) RGD PMID:15243130 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
negative regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkia cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within ISO (PMID:7905001) RGD PMID:7905001 NCBI chr 2:96,306,181...96,380,959
Ensembl chr 2:94,398,869...94,414,282 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta acts_upstream_of_or_within ISO (PMID:7905001) RGD PMID:7905001 NCBI chr20:37,511,564...37,608,607
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:22674394) RGD PMID:22674394 NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
negative regulation of CoA-transferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir27a microRNA 27a involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr19:40,859,603...40,859,689
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr17:1,819,147...1,819,243
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
negative regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln1 egl-9 family hypoxia-inducible factor 1 involved_in IDA
IMP		 PMID:22975349 RGD
BHF-UCL		 PMID:22975349 PMID:22975349 RGD:8554232, RGD:8554232 NCBI chr19:69,765,276...69,804,681
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Rgn regucalcin IDA RGD PMID:1656206 RGD:9590243 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:8876165) RGD PMID:8876165 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in ISO (PMID:8684460) RGD PMID:8684460 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in ISO (PMID:11746698) RGD PMID:11746698 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in ISS
ISO		 GO_REF:0000024
(PMID:8521819)		 UniProt
RGD		 PMID:8521819 GO_REF:0000024 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO MGI:2178778 (PMID:12970760) RGD PMID:12970760 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11882646)		 UniProt
RGD		 PMID:11882646 GO_REF:0000024 NCBI chr 3:163,189,435...163,333,003
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IDA RGD PMID:10721722 RGD:632478 NCBI chr 5:88,807,402...88,976,005
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IDA RGD PMID:10721722 RGD:632478 NCBI chr10:82,390,845...82,402,814
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (PMID:12130539) RGD PMID:12130539 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B acts_upstream_of_or_within
involved_in		 IMP
ISO		 (PMID:12130539)
(PMID:28666995)		 RGD PMID:12130539 PMID:28666995 PMID:22584582 RGD:10045364 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:8259215)
(PMID:12130539)
(PMID:7739547)		 RGD PMID:7739547 PMID:8259215 PMID:12130539 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C acts_upstream_of_or_within ISO (PMID:7739547) RGD PMID:7739547 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of_or_within ISO (PMID:21652635) RGD PMID:21652635 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Hexim2 HEXIM P-TEFb complex subunit 2 involved_in ISO (PMID:15713662) RGD PMID:15713662 NCBI chr10:88,572,102...88,584,856
Ensembl chr10:88,079,014...88,084,775 		JBrowse link
G Hhex hematopoietically expressed homeobox involved_in ISO (PMID:12554669) RGD PMID:12554669 NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO (PMID:21540187)
MGI:5292392 (PMID:21540187)		 RGD PMID:21540187 NCBI chr10:55,900,610...55,912,975
Ensembl chr10:55,401,982...55,414,114 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:19773423) RGD PMID:19773423 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:9988268) RGD PMID:9988268 NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (PMID:12853976) RGD PMID:12853976 NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G Men1 menin 1 involved_in ISO (PMID:15640349) RGD PMID:15640349 NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir711 microRNA 711 involved_in ISO (PMID:26735582) RGD PMID:26735582 NCBI chr 8:109,621,975...109,622,042
Ensembl chr 8:109,621,975...109,622,042 		JBrowse link
G Myocd myocardin involved_in ISO (PMID:18451334) RGD PMID:18451334 NCBI chr10:50,332,356...50,426,819
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 involved_in ISO (PMID:19210544) RGD PMID:19210544 NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:21241890) RGD PMID:21241890 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,507,242...11,525,794
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:15962316) RGD PMID:15962316 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Wee2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (PMID:21454751) RGD PMID:21454751 NCBI chr 4:69,239,043...69,261,576
Ensembl chr 4:69,239,299...69,261,093 		JBrowse link
negative regulation of cystathionine beta-synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:24416422) RGD PMID:24416422 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) RGD PMID:19944011 NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IDA RGD PMID:19240864 RGD:7411612 NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Crb2 crumbs cell polarity complex component 2 involved_in ISO (PMID:20299451) RGD PMID:20299451 NCBI chr 3:41,946,694...41,974,629
Ensembl chr 3:21,542,221...21,563,294 		JBrowse link
G Fetub fetuin B involved_in ISS
ISO		 GO_REF:0000024
(PMID:23562279)		 UniProt
RGD		 PMID:23562279 GO_REF:0000024 NCBI chr11:91,586,750...91,599,789
Ensembl chr11:78,082,156...78,095,135 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:22832495) RGD PMID:22832495 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in IC PMID:8626514 BHF-UCL PMID:8626514 RGD:8554276 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in IC PMID:8626514 BHF-UCL PMID:8626514 RGD:8554276 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Mir339 microRNA 339 involved_in ISO (PMID:24352696) RGD PMID:24352696 NCBI chr12:20,391,395...20,391,490
Ensembl chr12:15,277,546...15,277,641 		JBrowse link
G Renbp renin binding protein IDA RGD PMID:11926999 RGD:727355 NCBI chr  X:156,812,785...156,821,860
Ensembl chr  X:151,661,458...151,670,516 		JBrowse link
G Serpinb13 serpin family B member 13 involved_in ISO (PMID:12504904) RGD PMID:12504904 NCBI chr13:23,633,220...23,665,100
Ensembl chr13:23,118,584...23,150,760 		JBrowse link
G Serpinb1a serpin family B member 1A involved_in ISO (PMID:30692621) RGD PMID:30692621 NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,590,677...31,599,102 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:21383048) RGD PMID:21383048 NCBI chr13:23,788,758...23,795,298
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Serpinb6a serpin family B member 6A involved_in ISO (PMID:17761692) RGD PMID:17761692 NCBI chr17:31,076,811...31,195,035
Ensembl chr17:30,871,468...31,014,427 		JBrowse link
G Serpinb8 serpin family B member 8 involved_in ISO (PMID:8530382) RGD PMID:8530382 NCBI chr13:24,141,557...24,164,894
Ensembl chr13:23,626,945...23,650,835 		JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Serpine1 serpin family E member 1 involved_in IDA
ISO
IC		 (PMID:1695900)
PMID:8626514		 RGD PMID:1695900 PMID:10717410 PMID:8626514 RGD:8547889, RGD:8554276 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 involved_in ISO (PMID:14511383) RGD PMID:14511383 NCBI chr17:6,746,892...7,227,034
Ensembl chr17:6,742,273...7,224,935 		JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 involved_in ISO (PMID:11751414) RGD PMID:11751414 NCBI chr16:31,149,698...31,582,280
Ensembl chr16:26,383,383...26,815,205 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:3903517)		 UniProt
RGD		 PMID:3903517 GO_REF:0000024 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Vtn vitronectin involved_in ISO (PMID:1695900) RGD PMID:1695900 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,394,719...63,397,810 		JBrowse link
negative regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 involved_in ISO (PMID:7539425) RGD PMID:7539425 NCBI chr19:45,109,880...45,134,819
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr10:105,690,400...105,696,070
Ensembl chr10:105,191,950...105,197,640 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in IDA
ISO
ISS		 PMID:17599051
(PMID:16648858)
(PMID:18046415)
GO_REF:0000024		 RGD
UniProt		 PMID:16648858 PMID:18046415 PMID:17599051 GO_REF:0000024, RGD:8553726 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A involved_in ISO (PMID:25744720) RGD PMID:25744720 NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:167,903,542...167,922,260 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr15:23,003,130...23,017,615
Ensembl chr15:20,523,183...20,542,494 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr 1:106,549,035...106,578,859
Ensembl chr 1:97,410,848...97,442,554 		JBrowse link
G Vps25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr10:86,696,330...86,701,871
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Zfyve28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) RGD PMID:19460345 NCBI chr14:76,468,424...76,554,039
Ensembl chr14:76,468,424...76,554,039 		JBrowse link
G Zgpat zinc finger CCCH-type and G-patch domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:19644445)		 UniProt
RGD		 PMID:19644445 GO_REF:0000024 NCBI chr 3:188,851,376...188,867,914
Ensembl chr 3:168,473,981...168,490,380 		JBrowse link
negative regulation of exonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO (PMID:15200954) RGD PMID:15200954 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15200954) RGD PMID:15200954 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of glucokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cox11 cytochrome c oxidase copper chaperone COX11 acts_upstream_of_or_within ISO (PMID:17069463) RGD PMID:17069463 NCBI chr10:75,955,825...75,962,398
Ensembl chr10:75,458,749...75,465,322 		JBrowse link
G Gckr glucokinase regulator involved_in
acts_upstream_of_or_within		 ISO (PMID:23621087)
MGI:2386670 (PMID:10713097)		 RGD PMID:10713097 PMID:23621087 NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:25,045,100...25,075,654 		JBrowse link
G Midn midnolin acts_upstream_of_or_within IDA PMID:24187134 MGI PMID:24187134 RGD:8655525 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:24187134)		 ParkinsonsUK-UCL
RGD		 PMID:24187134 GO_REF:0000024 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of glycogen (starch) synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:19250614) RGD PMID:19250614 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
negative regulation of glycogen synthase activity, transferring glucose-1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:17569761) RGD PMID:17569761 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
negative regulation of GTPase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:15870074 RGD:2325307 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Amot angiomotin acts_upstream_of_or_within ISO MGI:2656627 (PMID:17699752) RGD PMID:17699752 NCBI chr  X:113,778,990...113,837,846
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Arfgef1 ARF guanine nucleotide exchange factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15644318)		 UniProt
RGD		 PMID:15644318 GO_REF:0000024 NCBI chr 5:13,764,507...13,859,237
Ensembl chr 5:8,981,540...9,076,326 		JBrowse link
G Arl2 ARF like GTPase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10831612)		 UniProt
RGD		 PMID:10831612 GO_REF:0000024 NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119 		JBrowse link
G Arrb1 arrestin, beta 1 IDA RGD PMID:1517224 RGD:631708 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 IDA RGD PMID:1517224 RGD:631708 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 acts_upstream_of_or_within ISO MGI:3055492 (PMID:23716571) RGD PMID:23716571 NCBI chr 8:68,627,739...68,661,232
Ensembl chr 8:59,731,912...59,765,607 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:19948740)
(PMID:20154697)		 UniProt
RGD		 PMID:19948740 PMID:20154697 GO_REF:0000024 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Gmip Gem-interacting protein involved_in ISO (PMID:12093360) RGD PMID:12093360 NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 involved_in ISO (PMID:11024022) RGD PMID:11024022 NCBI chr 3:29,538,929...29,565,921
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) RGD PMID:23027131 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Klre1 killer cell lectin like receptor E1 involved_in ISO (PMID:22585739) RGD PMID:22585739 NCBI chr 4:164,719,307...164,727,664
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in ISO (PMID:22585739) RGD PMID:22585739 NCBI chr 4:164,767,377...164,778,453
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Lrch1 leucine rich repeats and calponin homology domain containing 1 involved_in ISO (PMID:28028151) RGD PMID:28028151 NCBI chr15:50,070,605...50,249,724
Ensembl chr15:50,071,947...50,249,657 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 acts_upstream_of_or_within ISO (PMID:22423108) RGD PMID:22423108 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mkks MKKS centrosomal shuttling protein acts_upstream_of_or_within ISO MGI:3608879 (PMID:23716571) RGD PMID:23716571 NCBI chr 3:144,654,563...144,672,831
Ensembl chr 3:124,201,877...124,220,162 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plxnb3 plexin B3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20696765)		 UniProt
RGD		 PMID:20696765 GO_REF:0000024 NCBI chr  X:156,645,505...156,660,011
Ensembl chr  X:151,494,207...151,508,674 		JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 IDA RGD PMID:16413169 RGD:1625628 NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:137,439,540...138,191,575 		JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 acts_upstream_of_or_within ISO MGI:3613572 (PMID:26975711), (PMID:29921611) RGD PMID:26975711 PMID:29921611 NCBI chr 2:230,173,713...230,318,555
Ensembl chr 2:227,500,367...227,645,169 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO (PMID:25074804)
(PMID:19738201), (PMID:25074804)		 RGD PMID:19738201 PMID:25074804 NCBI chr 5:158,277,476...158,300,294
Ensembl chr 5:152,993,665...153,017,205 		JBrowse link
G Rdx radixin involved_in ISO (PMID:22467863) RGD PMID:22467863 NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rgn regucalcin IMP RGD PMID:11510494 RGD:9590205 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Rrp1b ribosomal RNA processing 1B involved_in ISO (PMID:18081427) RGD PMID:18081427 NCBI chr20:10,122,825...10,148,404
Ensembl chr20:10,123,125...10,147,928 		JBrowse link
G Sh3bp4 SH3-domain binding protein 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22575674)		 UniProt
RGD		 PMID:22575674 GO_REF:0000024 NCBI chr 9:97,107,877...97,186,878
Ensembl chr 9:89,660,156...89,739,163 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within ISO (PMID:11585837) RGD PMID:11585837 NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 acts_upstream_of_or_within ISO (PMID:11585837) RGD PMID:11585837 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10761932)		 UniProt
RGD		 PMID:10761932 GO_REF:0000024 NCBI chr12:37,713,522...37,722,606
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Tsc1 TSC complex subunit 1 IMP RGD PMID:15611338 RGD:1601406 NCBI chr 3:32,367,434...32,416,565
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Ttc8 tetratricopeptide repeat domain 8 acts_upstream_of_or_within ISO (PMID:23716571) RGD PMID:23716571 NCBI chr 6:123,927,657...124,025,354
Ensembl chr 6:118,198,201...118,252,418 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:146,739,978...146,750,961
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(PMID:27471269)		 RGD PMID:21928830 PMID:27471269 PMID:30559291 NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622 		JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gckr glucokinase regulator IDA RGD PMID:14627435 RGD:1598592 NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:25,045,100...25,075,654 		JBrowse link
negative regulation of hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within ISO MGI:104993 (PMID:15995171) RGD PMID:15995171 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15528193)		 UniProt
RGD		 PMID:15528193 GO_REF:0000024 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23502535)		 UniProt
RGD		 PMID:23502535 GO_REF:0000024 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Grn granulin precursor acts_upstream_of_or_within ISO MGI:3762618 (PMID:28728022) RGD PMID:28728022 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:88049 (PMID:15995171) RGD PMID:15995171 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO MGI:1857227 (PMID:12074580) RGD PMID:12074580 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos3 nitric oxide synthase 3 acts_upstream_of_or_within ISO MGI:2150145 (PMID:12074580) RGD PMID:12074580 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Prkcz protein kinase C, zeta IDA inhibition of acid sphingomyelinase translocation to cell surface and activation RGD PMID:17346242 RGD:1642658 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Serpina5 serpin family A member 5 involved_in ISO (PMID:8665956) RGD PMID:8665956 NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aida axin interactor, dorsalization associated acts_upstream_of_or_within ISO (PMID:17681137) RGD PMID:17681137 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24512202)		 UniProt
RGD		 PMID:24512202 GO_REF:0000024 NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (PMID:15306813) RGD PMID:15306813 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD PMID:16636664 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 involved_in ISO (PMID:11034606) RGD PMID:11034606 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IMP PMID:21076496 RGD
UniProt		 PMID:12064607 PMID:21076496 RGD:1299562, RGD:13673827 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:22399583) RGD PMID:22399583 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:21383048) RGD PMID:21383048 NCBI chr13:23,788,758...23,795,298
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO MGI:108078|MGI:1860298 (PMID:19300477) RGD PMID:19300477 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:1860298|MGI:892014 (PMID:19300477) RGD PMID:19300477 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sfrp5 secreted frizzled-related protein 5 acts_upstream_of_or_within ISO MGI:108078|MGI:892014 (PMID:19300477) RGD PMID:19300477 NCBI chr 1:250,956,050...250,960,512
Ensembl chr 1:241,006,762...241,011,224 		JBrowse link
negative regulation of kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO (PMID:15870270) RGD PMID:15870270 NCBI chr15:31,989,796...32,000,042
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in ISO (PMID:19170105) RGD PMID:19170105 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in ISO (PMID:19170105) RGD PMID:19170105 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10411542 RGD:5134371 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:19762078 RGD:150429972 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) RGD PMID:10490622 NCBI chr13:92,609,791...92,618,580
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (PMID:19523444) RGD PMID:19523444 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Mstn myostatin involved_in ISO (PMID:19357233) RGD PMID:19357233 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit involved_in ISO (PMID:18616680) RGD PMID:18616680 NCBI chr 8:117,094,443...117,097,639
Ensembl chr 8:108,215,814...108,218,996 		JBrowse link
G Prdx3 peroxiredoxin 3 involved_in ISO (PMID:18205602) RGD PMID:18205602 NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 IDA RGD PMID:9366267 RGD:5134981 NCBI chr10:102,199,949...102,221,642
Ensembl chr10:101,701,096...101,750,751 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 IDA due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
negative regulation of lipase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 IDA RGD PMID:10419291 RGD:1626385 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in
acts_upstream_of_or_within		 ISO (PMID:14967812)
MGI:2157148 (PMID:10357838)		 RGD PMID:10357838 PMID:14967812 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22532565)		 UniProt
RGD		 PMID:22532565 GO_REF:0000024 NCBI chr 9:1,026,910...1,033,352
Ensembl chr 9:939,747...946,120 		JBrowse link
G Por cytochrome p450 oxidoreductase IDA phospholipase D RGD PMID:18801337 RGD:4889814 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
negative regulation of lipoprotein lipase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl3 angiopoietin-like 3 involved_in ISO (PMID:17110602), (PMID:19542565) RGD PMID:17110602 PMID:19542565 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Angptl4 angiopoietin-like 4 involved_in TAS
ISO		 (PMID:12401877)
(PMID:19542565), (PMID:29899144)		 RGD PMID:12401877 PMID:19542565 PMID:29899144 PMID:14570927 RGD:1302799 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:11060345), (PMID:18635818), (PMID:3973011) RGD PMID:3973011 PMID:11060345 PMID:18635818 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Mir138-1 microRNA 138-1 involved_in ISO (PMID:31769250) RGD PMID:31769250 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir138-2 microRNA 138-2 involved_in ISO (PMID:31769250) RGD PMID:31769250 NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274 		JBrowse link
negative regulation of lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:20110805), (PMID:20501872) RGD PMID:20110805 PMID:20501872 NCBI chr 3:28,791,062...28,792,905 JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:19460854)		 UniProt
RGD		 PMID:19460854 GO_REF:0000024 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agt angiotensinogen involved_in ISO (PMID:28283184) RGD PMID:28283184 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:9685360) RGD PMID:9685360 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180364 (PMID:12388746) RGD PMID:12388746 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:16254138) RGD PMID:16254138 NCBI chr10:100,428,826...100,441,693
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21283629)		 UniProt
RGD		 PMID:21283629 GO_REF:0000024 NCBI chr10:82,390,845...82,402,814
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:12813029), (PMID:20154697)		 UniProt
RGD		 PMID:12813029 PMID:20154697 GO_REF:0000024 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:7593328)		 UniProt
RGD		 PMID:7593328 GO_REF:0000024 NCBI chr10:17,184,853...17,187,646 JBrowse link
G Dusp7 dual specificity phosphatase 7 involved_in ISO (PMID:9788880) RGD PMID:9788880 NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:107,008,528...107,016,404 		JBrowse link
G Fem1a fem-1 homolog A acts_upstream_of_or_within ISO (PMID:18270204) RGD PMID:18270204 NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:17182785 RGD:2301767 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:11408560) RGD PMID:11408560 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase acts_upstream_of_or_within ISO MGI:97306 (PMID:12409258), (PMID:16271875) RGD PMID:12409258 PMID:16271875 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12676986)		 UniProt
RGD		 PMID:12676986 GO_REF:0000024 NCBI chr 8:117,121,802...117,125,494
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:16865359) RGD PMID:16865359 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) RGD PMID:12556481 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (PMID:17379480) RGD PMID:17379480 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Kng2 kininogen 2 IDA in ConA- or PHA-stimulated Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr11:91,418,470...91,440,841
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:9252121)		 UniProt
RGD		 PMID:9252121 GO_REF:0000024 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mir218-2 microRNA 218-2 involved_in ISO (PMID:21385766) RGD PMID:21385766 NCBI chr10:20,068,451...20,068,560
Ensembl chr10:20,068,451...20,068,560 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO MGI:1857478|MGI:2176055|MGI:2176057|MGI:96159|MGI:96677|MGI:96974 (PMID:10620616), (PMID:11297510), (PMID:12409258), (PMID:16271875) RGD PMID:10620616 PMID:11297510 PMID:12409258 PMID:16271875 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO (PMID:11489947) RGD PMID:11489947 NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 acts_upstream_of_or_within ISO (PMID:17724343)
MGI:3757569 (PMID:17724343)		 RGD PMID:17724343 NCBI chr14:12,766,539...12,796,461
Ensembl chr14:12,462,563...12,479,994 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:22045810) RGD PMID:22045810 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IDA RGD PMID:9857190 RGD:10044039 NCBI chr 1:106,756,896...106,817,369
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within ISO MGI:1856074 (PMID:9064344), (PMID:9254656) RGD PMID:9064344 PMID:9254656 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:19494114)
(PMID:12833140)		 RGD PMID:12833140 PMID:19494114 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20837545)		 UniProt
RGD		 PMID:20837545 GO_REF:0000024 NCBI chr17:9,254,112...9,268,233
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (PMID:19127022) RGD PMID:19127022 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within ISO (PMID:16339969) RGD PMID:16339969 NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 acts_upstream_of_or_within ISO (PMID:16339969) RGD PMID:16339969 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 acts_upstream_of_or_within ISO (PMID:16339969) RGD PMID:16339969 NCBI chr18:30,687,633...30,702,546
Ensembl chr18:30,436,443...30,453,004 		JBrowse link
G Stk38 serine/threonine kinase 38 involved_in ISO (PMID:17906693) RGD PMID:17906693 NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198 		JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:14612383 RGD:1580517 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:19477270) RGD PMID:19477270 NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir152 microRNA 152 involved_in ISO (PMID:24813629) RGD PMID:24813629 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs involved_in ISO (PMID:18194466)
(PMID:24812324)		 RGD PMID:18194466 PMID:24812324 NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:58,102,981...58,169,502 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO (PMID:24812324) RGD PMID:24812324 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:28358369) RGD PMID:28358369 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISO (PMID:9573338) RGD PMID:9573338 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 involved_in ISO (PMID:9573338) RGD PMID:9573338 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
negative regulation of monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir130b microRNA 130b involved_in ISO (PMID:25802328) RGD PMID:25802328 NCBI chr11:97,384,380...97,384,461
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:16982751) RGD PMID:16982751 NCBI chr17:1,819,147...1,819,243
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
negative regulation of NAD(P)H oxidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd5 dopamine receptor D5 involved_in ISO (PMID:16352863) RGD PMID:16352863 NCBI chr14:76,700,244...76,703,344
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Il13 interleukin 13 IMP RGD PMID:19752235 RGD:8549634 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:11443198) RGD PMID:11443198 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IMP RGD PMID:16537391 RGD:1582129 NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2154537 (PMID:16380094), (PMID:18951881) RGD PMID:16380094 PMID:18951881 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within ISO MGI:2180562 (PMID:11159934) RGD PMID:11159934 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Gla galactosidase, alpha involved_in ISO (PMID:15668341) RGD PMID:15668341 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:18005341 RGD:10045554 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Mir138-1 microRNA 138-1 involved_in ISO (PMID:24244340) RGD PMID:24244340 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir138-2 microRNA 138-2 involved_in ISO (PMID:24244340) RGD PMID:24244340 NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:28602162) RGD PMID:28602162 NCBI chr 8:127,633,048...127,633,137
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Nosip nitric oxide synthase interacting protein involved_in ISO (PMID:11149895) RGD PMID:11149895 NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650 		JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
negative regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 involved_in ISO (PMID:17611195) RGD PMID:17611195 NCBI chr 8:66,446,106...66,452,844
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
negative regulation of oxidoreductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G Hp haptoglobin involved_in ISO (PMID:19740759) RGD PMID:19740759 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21320589)		 UniProt
RGD		 PMID:21320589 GO_REF:0000024 NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in IMP PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chr16:6,328,925...6,336,978
Ensembl chr16:6,322,236...6,330,537 		JBrowse link
G Oxa1l OXA1L, mitochondrial inner membrane protein involved_in ISO (PMID:17936786) RGD PMID:17936786 NCBI chr15:31,783,725...31,791,353
Ensembl chr15:27,813,625...27,821,319 		JBrowse link
G Prdx5 peroxiredoxin 5 involved_in ISO (PMID:15280035) RGD PMID:15280035 NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (PMID:18698006) RGD PMID:18698006 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
G Tmlhe trimethyllysine hydroxylase, epsilon involved_in ISO (PMID:15754339) RGD PMID:15754339 NCBI chr20:91,234...138,942
Ensembl chr20:91,272...140,386 		JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin acts_upstream_of_or_within ISO MGI:88264 (PMID:21849499) RGD PMID:21849499 NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cst3 cystatin C involved_in ISO (PMID:6203523), (PMID:7890620) RGD PMID:6203523 PMID:7890620 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Csta cystatin A involved_in ISO (PMID:6203523) RGD PMID:6203523 NCBI chr11:78,125,813...78,136,818
Ensembl chr11:64,620,483...64,631,488 		JBrowse link
G Cstb cystatin B involved_in ISO (PMID:6203523) RGD PMID:6203523 NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Cyss cystatin S IDA Papain
Ficin		 RGD PMID:7575236 PMID:3263967 RGD:2306757, RGD:1299643 NCBI chr 3:157,892,660...157,897,265
Ensembl chr 3:137,432,049...137,436,610 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16512877)		 UniProt
RGD		 PMID:16512877 GO_REF:0000024 NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Eppin epididymal peptidase inhibitor involved_in ISS
ISO		 GO_REF:0000024
(PMID:18331357)		 UniProt
RGD		 PMID:18331357 GO_REF:0000024 NCBI chr 3:173,731,739...173,738,651
Ensembl chr 3:153,312,396...153,319,310 		JBrowse link
G Serpinb3 serpin family B member 3 involved_in ISO (PMID:12949073) RGD PMID:12949073 NCBI chr13:23,788,758...23,795,298
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:12949073) RGD PMID:12949073 NCBI chr13:23,755,690...23,766,188
Ensembl chr13:23,236,972...23,246,985 		JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (PMID:15509762), (PMID:18398001) RGD PMID:15509762 PMID:18398001 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Smr3b submaxillary gland androgen regulated protein 3B involved_in IDA PMID:12835417 UniProt PMID:12835417 RGD:8553855 NCBI chr14:20,067,850...20,072,520
Ensembl chr14:19,783,816...19,788,492 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 acts_upstream_of_or_within ISO (PMID:3428272) RGD PMID:3428272 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
negative regulation of phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10593895)		 UniProt
RGD		 PMID:10593895 GO_REF:0000024 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) RGD PMID:18617530 NCBI chr 1:7,547,369...7,673,449
Ensembl chr 1:5,727,066...5,920,555 		JBrowse link
G Tmem225 transmembrane protein 225 involved_in ISO (PMID:25605614) RGD PMID:25605614 NCBI chr 8:49,394,638...49,397,196
Ensembl chr 8:40,497,483...40,500,041 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in ISO (PMID:17936702) RGD PMID:17936702 NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:90,646,393...90,709,026 		JBrowse link
negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag4 BAG cochaperone 4 involved_in ISO (PMID:21712384) RGD PMID:21712384 NCBI chr16:72,991,407...73,008,620
Ensembl chr16:66,288,678...66,308,663 		JBrowse link
negative regulation of phospholipase A2 activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IDA RGD PMID:2969352 RGD:7421659 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa8 annexin A8 involved_in ISO (PMID:2530088) RGD PMID:2530088 NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISO (PMID:11830583) RGD PMID:11830583 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
negative regulation of phospholipase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl3 angiopoietin-like 3 involved_in ISO (PMID:17110602) RGD PMID:17110602 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (PMID:19127022) RGD PMID:19127022 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
negative regulation of polynucleotide adenylyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp36 zinc finger protein 36 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22844456)		 UniProt
RGD		 PMID:22844456 GO_REF:0000024 NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
negative regulation of primary amine oxidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IDA PMID:8524413 BHF-UCL PMID:8524413 RGD:8554844 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt1s1 AKT1 substrate 1 involved_in ISO (PMID:17386266) RGD PMID:17386266 NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:95,332,898...95,339,677 		JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within ISO (PMID:14600260) RGD PMID:14600260 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22496641)		 UniProt
RGD		 PMID:22496641 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cep43 centrosomal protein 43 involved_in ISO (PMID:17888034) RGD PMID:17888034 NCBI chr 1:55,080,983...55,111,509
Ensembl chr 1:52,533,428...52,563,923 		JBrowse link
G Cep85 centrosomal protein 85 involved_in ISO (PMID:26220856) RGD PMID:26220856 NCBI chr 5:151,640,316...151,687,891
Ensembl chr 5:146,356,576...146,404,060 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in IDA PMID:12966074 UniProt PMID:12966074 RGD:8553340 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:17289031 RGD:9587773 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dbndd2 dysbindin domain containing 2 involved_in ISO (PMID:16618118) RGD PMID:16618118 NCBI chr 3:173,634,551...173,639,999
Ensembl chr 3:153,191,090...153,220,651 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO (PMID:19446321) RGD PMID:19446321 NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:15601829) RGD PMID:15601829 NCBI chr10:11,361,168...11,386,599
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Drd1 dopamine receptor D1 IMP RGD PMID:12688394 RGD:1581394 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd5 dopamine receptor D5 IMP RGD PMID:12688394 RGD:1581394 NCBI chr14:76,700,244...76,703,344
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:85,945,289...86,081,289
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Epha1 Eph receptor A1 involved_in ISO (PMID:19118217) RGD PMID:19118217 NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:71,246,409...71,260,846 		JBrowse link
G Fabp4 fatty acid binding protein 4 acts_upstream_of_or_within ISO MGI:2148887 (PMID:15684432) RGD PMID:15684432 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha acts_upstream_of_or_within ISO (PMID:12124778) RGD PMID:12124778 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta acts_upstream_of_or_within ISO (PMID:12124778) RGD PMID:12124778 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma acts_upstream_of_or_within ISO (PMID:12124778) RGD PMID:12124778 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gnaq G protein subunit alpha q involved_in ISO (PMID:20399743) RGD PMID:20399743 NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gskip GSK3B interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:16981698)		 UniProt
RGD		 PMID:16981698 GO_REF:0000024 NCBI chr 6:130,357,241...130,373,221
Ensembl chr 6:124,586,070...124,609,100 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in IMP
ISO		 (PMID:16636664) RGD PMID:16636664 PMID:21668448 RGD:10401931 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in ISO (PMID:15731106) RGD PMID:15731106 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Il6 interleukin 6 IDA Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ilk integrin-linked kinase IMP GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO (PMID:12556481) RGD PMID:12556481 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:46,549,994...46,564,735
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:25447536) RGD PMID:25447536 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mllt1 MLLT1, super elongation complex subunit acts_upstream_of_or_within ISO (PMID:11007757) RGD PMID:11007757 NCBI chr 9:1,731,077...1,775,985
Ensembl chr 9:1,731,080...1,775,970 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO MGI:1339753|MGI:1857478 (PMID:16835260), (PMID:17053831) RGD PMID:16835260 PMID:17053831 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor acts_upstream_of_or_within ISO (PMID:14580336), (PMID:16405865) RGD PMID:14580336 PMID:16405865 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Pcp4 Purkinje cell protein 4 IDA RGD PMID:10751438 RGD:1579763 NCBI chr11:49,229,185...49,331,186
Ensembl chr11:35,800,713...35,861,725 		JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha acts_upstream_of_or_within TAS
ISO		 (PMID:9218452) RGD PMID:9218452 PMID:1491692 RGD:729428 NCBI chr 2:96,306,181...96,380,959
Ensembl chr 2:94,398,869...94,414,282 		JBrowse link
G Pkig cAMP-dependent protein kinase inhibitor gamma acts_upstream_of_or_within ISO (PMID:9218452) RGD PMID:9218452 NCBI chr 3:172,749,871...172,817,514
Ensembl chr 3:152,366,041...152,398,082 		JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO MGI:5475202 (PMID:23223530) RGD PMID:23223530 NCBI chr19:41,346,855...41,374,832
Ensembl chr19:24,442,122...24,470,107 		JBrowse link
G Plec plectin involved_in ISO (PMID:12200133) RGD PMID:12200133 NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26095851)		 UniProt
RGD		 PMID:26095851 GO_REF:0000024 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent, 1E involved_in ISO (PMID:11864573) RGD PMID:11864573 NCBI chr10:72,548,906...72,684,702
Ensembl chr10:72,055,208...72,187,282 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in ISO (PMID:17255938) RGD PMID:17255938 NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,010,890...10,252,142 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO MGI:2182091|MGI:3512112 (PMID:18316483) RGD PMID:18316483 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prkca protein kinase C, alpha acts_upstream_of_or_within ISO MGI:2679305 (PMID:11923480) RGD PMID:11923480 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkrip1 PRKR interacting protein 1 acts_upstream_of_or_within ISO (PMID:12679338) RGD PMID:12679338 NCBI chr12:26,107,422...26,128,404
Ensembl chr12:20,470,820...20,489,115 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:12805290) RGD PMID:12805290 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO		 GO_REF:0000024
(PMID:10970857)
(PMID:9197241)		 UniProt
RGD		 PMID:9197241 PMID:10970857 GO_REF:0000024 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:P21675 (PMID:9858607)		 UniProt
RGD		 PMID:9858607 GO_REF:0000024 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rgn regucalcin IMP RGD PMID:11455566 RGD:9590207 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Rtraf RNA transcription, translation and transport factor involved_in ISO (PMID:15147888) RGD PMID:15147888 NCBI chr15:4,482,699...4,507,115
Ensembl chr15:4,442,573...4,457,972 		JBrowse link
G Sh3bp5 SH3-domain binding protein 5 involved_in ISO (PMID:10339589) RGD PMID:10339589 NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,583,465...6,698,975 		JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO MGI:3721903 (PMID:23528453) RGD PMID:23528453 NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:59,678,216...59,785,538 		JBrowse link
G Smyd3 SET and MYND domain containing 3 acts_upstream_of_or_within ISO (PMID:23752591) RGD PMID:23752591 NCBI chr13:93,241,274...93,798,221
Ensembl chr13:90,709,270...91,266,253 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:18391197) RGD PMID:18391197 NCBI chr18:29,704,182...29,713,382
Ensembl chr18:29,452,943...29,462,134 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IDA PMID:15093746 UniProt PMID:15093746 RGD:8553684 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (PMID:15299019) RGD PMID:15299019 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12791994)		 UniProt
RGD		 PMID:12791994 GO_REF:0000024 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim27 tripartite motif-containing 27 involved_in ISO (PMID:22128329) RGD PMID:22128329 NCBI chr17:48,233,999...48,246,348
Ensembl chr17:43,538,285...43,550,643 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:15249583) RGD PMID:15249583 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:20585042), (PMID:27609517) RGD PMID:20585042 PMID:27609517 NCBI chr 8:50,282,510...50,430,034
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 involved_in ISO (PMID:22504299) RGD PMID:22504299 NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO MGI:6414871 (PMID:30765526) RGD PMID:30765526 NCBI chr10:86,702,828...86,719,917
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
negative regulation of protein kinase activity by regulation of protein phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in ISS
ISO		 GO_REF:0000024
(PMID:18362360)
(PMID:18362360), (PMID:19651874)		 UniProt
RGD		 PMID:18362360 PMID:19651874 GO_REF:0000024 NCBI chr 2:177,436,076...177,475,969
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21289159)		 UniProt
RGD		 PMID:21289159 GO_REF:0000024 NCBI chr20:11,222,171...11,350,416
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21283629)		 UniProt
RGD		 PMID:21283629 GO_REF:0000024 NCBI chr10:82,390,845...82,402,814
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Coro1c coronin 1C involved_in ISO (PMID:19913511) RGD PMID:19913511 NCBI chr12:48,373,573...48,445,718
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO (PMID:23977283) RGD PMID:23977283 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within ISO MGI:109583 (PMID:20418913) RGD PMID:20418913 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Npm1 nucleophosmin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12882984)		 UniProt
RGD		 PMID:12882984 GO_REF:0000024 NCBI chr10:18,245,739...18,255,913
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1921405 (PMID:20418913) RGD PMID:20418913 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
negative regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19223857)		 UniProt
RGD		 PMID:19223857 GO_REF:0000024 NCBI chr10:82,390,845...82,402,814
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:19903888)
(PMID:20154697)		 UniProt
RGD		 PMID:19903888 PMID:20154697 GO_REF:0000024 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 acts_upstream_of_or_within ISO MGI:1856628 (PMID:25297099) RGD PMID:25297099 NCBI chr17:19,891,313...19,982,770
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in ISO (PMID:23329839) RGD PMID:23329839 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO (PMID:19107203) RGD PMID:19107203 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in ISO (PMID:19107203) RGD PMID:19107203 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:22194607) RGD PMID:22194607 NCBI chr17:8,484,340...8,547,268
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22696064) RGD PMID:22696064 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir24-2 microRNA 24-2 involved_in ISO (PMID:21788589) RGD PMID:21788589 NCBI chr19:40,859,455...40,859,562
Ensembl chr19:23,954,683...23,954,790 		JBrowse link
G Mir34a microRNA 34a acts_upstream_of ISO (PMID:26330104) RGD PMID:26330104 NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Prkch protein kinase C, eta involved_in ISO (PMID:34593629) RGD PMID:34593629 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:12486103) RGD PMID:12486103 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 acts_upstream_of_or_within ISO (PMID:29274751) RGD PMID:29274751 NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 acts_upstream_of_or_within ISO (PMID:29274751) RGD PMID:29274751 NCBI chr 6:106,605,611...106,739,208
Ensembl chr 6:100,874,369...101,007,508 		JBrowse link
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggnbp2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO MGI:4072637 (PMID:26764350) RGD PMID:26764350 NCBI chr10:69,711,527...69,743,134
Ensembl chr10:69,711,532...69,743,365 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12676986)		 UniProt
RGD		 PMID:12676986 GO_REF:0000024 NCBI chr 8:117,121,802...117,125,494
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:9151699) RGD PMID:9151699 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Mvp major vault protein involved_in ISO (PMID:16441665) RGD PMID:16441665 NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:181,594,734...181,622,380 		JBrowse link
G Ptk6 protein tyrosine kinase 6 involved_in ISO (PMID:15539407) RGD PMID:15539407 NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO (PMID:21216966) RGD PMID:21216966 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17525734)		 UniProt
RGD		 PMID:17525734 GO_REF:0000024 NCBI chr10:82,502,911...82,569,882
Ensembl chr10:82,504,393...82,571,040 		JBrowse link
negative regulation of Rho-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chordc1 cysteine and histidine rich domain containing 1 involved_in ISO (PMID:20230755) RGD PMID:20230755 NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 involved_in ISO (PMID:26780829) RGD PMID:26780829 NCBI chr11:80,512,096...80,600,150
Ensembl chr11:66,957,190...67,095,051 		JBrowse link
G Rasip1 Ras interacting protein 1 involved_in ISO (PMID:26780829) RGD PMID:26780829 NCBI chr 1:96,097,135...96,109,564
Ensembl chr 1:96,091,074...96,109,562 		JBrowse link
negative regulation of RNA-dependent RNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4a2 eukaryotic translation initiation factor 4A2 involved_in ISO (PMID:11922617) RGD PMID:11922617 NCBI chr11:91,268,730...91,276,738
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
negative regulation of serine C-palmitoyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO MGI:2137691|MGI:6382064 (PMID:28275141), (PMID:31880535) RGD PMID:28275141 PMID:31880535 NCBI chr10:84,086,317...84,092,673
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa8 annexin A8 involved_in ISO (PMID:2530088) RGD PMID:2530088 NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr15:98,588,433...98,588,519
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO (PMID:24998411) RGD PMID:24998411 NCBI chr  X:137,343,058...137,343,153
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Serpina1 serpin family A member 1 IDA RGD PMID:19240864 RGD:7411612 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 acts_upstream_of_or_within IDA
ISO		 MGI:3613294 (PMID:20110462), (PMID:22228629) RGD PMID:20110462 PMID:22228629 PMID:12771515 RGD:724699 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 acts_upstream_of_or_within ISO (PMID:21705336) RGD PMID:21705336 NCBI chr14:31,321,976...31,328,622
Ensembl chr14:30,967,714...30,974,326 		JBrowse link
G Spink6 serine peptidase inhibitor, Kazal type 6 acts_upstream_of_or_within ISO (PMID:24352040) RGD PMID:24352040 NCBI chr18:36,648,725...36,660,902
Ensembl chr18:36,397,910...36,409,819 		JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 acts_upstream_of_or_within ISO MGI:3573756 (PMID:20179351) RGD PMID:20179351 NCBI chr18:36,515,347...36,584,038
Ensembl chr18:36,264,452...36,332,185 		JBrowse link
negative regulation of transferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln8 CLN8, transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO MGI:1856959 (PMID:8873145) RGD PMID:8873145 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774 		JBrowse link
G Setd7 SET domain containing 7, histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:23509280) RGD PMID:23509280 NCBI chr 2:137,713,545...137,756,319
Ensembl chr 2:135,562,683...135,605,468 		JBrowse link
negative regulation of ubiquitin protein ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:11988738), (PMID:16921029), (PMID:23708605), (PMID:29875408) RGD PMID:11988738 PMID:16921029 PMID:23708605 PMID:29875408 NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in ISO (PMID:11459825) RGD PMID:11459825 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11459826)		 UniProt
RGD		 PMID:11459826 GO_REF:0000024 NCBI chr 5:163,846,678...163,859,851
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpl23 ribosomal protein L23 involved_in ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:83,268,223...83,272,184
Ensembl chr10:82,771,538...82,775,870 		JBrowse link
G Rpl5 ribosomal protein L5 involved_in ISO (PMID:18560357) RGD PMID:18560357 NCBI chr14:1,988,792...1,995,236
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:50,994,581...50,999,447
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (PMID:17443180) RGD PMID:17443180 NCBI chr 7:30,251,142...30,301,185
Ensembl chr 7:28,364,033...28,410,053 		JBrowse link
negative regulation of ubiquitin-protein transferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20823226) RGD PMID:20823226 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Bag5 BAG cochaperone 5 involved_in IDA PMID:15603737 BHF-UCL PMID:15603737 RGD:8553807 NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9878046) RGD PMID:9878046 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:24790097) RGD PMID:24790097 NCBI chr11:78,320,225...78,329,837
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:23708001) RGD PMID:23708001 NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Psen1 presenilin 1 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
negative regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubxn1 UBX domain protein 1 involved_in ISO (PMID:21135095) RGD PMID:21135095 NCBI chr 1:215,194,418...215,198,343
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:28759036) RGD PMID:28759036 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B involved_in ISO (PMID:26063811) RGD PMID:26063811 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Ptprh protein tyrosine phosphatase, receptor type, H involved_in ISO (PMID:26063811) RGD PMID:26063811 NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:26063811) RGD PMID:26063811 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O involved_in ISO (PMID:26063811) RGD PMID:26063811 NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:170,164,431...170,374,771 		JBrowse link
G Ptprt protein tyrosine phosphatase, receptor type, T involved_in ISO (PMID:24846175) RGD PMID:24846175 NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of molecular function 1590
        regulation of catalytic activity 1006
          negative regulation of catalytic activity 355
            negative regulation of helicase activity 0
            negative regulation of hydrolase activity + 113
            negative regulation of lyase activity + 13
            negative regulation of oxidoreductase activity + 28
            negative regulation of transferase activity + 205
paths to the root