Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Stroke | | ISO | LRCH1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29531354 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Stroke | | ISO | LRCH1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29531354 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | GOA pipeline | RGD automated data pipeline |
3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Lrch1 (Rattus norvegicus - Norway rat) |
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LRCH1 (Homo sapiens - human) |
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Lrch1 (Mus musculus - house mouse) |
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Lrch1 (Chinchilla lanigera - long-tailed chinchilla) |
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LRCH1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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LRCH1 (Canis lupus familiaris - dog) |
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Lrch1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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LRCH1 (Sus scrofa - pig) |
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LRCH1 (Chlorocebus sabaeus - green monkey) |
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Lrch1 (Heterocephalus glaber - naked mole-rat) |
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Variants in Lrch1
1041 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D15Rat46 |
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RH132838 |
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RH130207 |
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RH137621 |
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BF390346 |
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D10Bir6 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 2 | 16 | 19 | 35 | 17 | 32 | 11 | ||||||
Low | 1 | 43 | 41 | 41 | 41 | 8 | 11 | 39 | 18 | 9 | 8 | ||
Below cutoff |
RefSeq Transcripts | NM_001134727 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006252311 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006252312 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006252313 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006252315 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008770896 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017599784 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017599785 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039093606 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274585 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063274586 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | BC166585 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH473951 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000015 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000047192 ⟹ ENSRNOP00000047801 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000097640 ⟹ ENSRNOP00000076612 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000108157 ⟹ ENSRNOP00000089380 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000108815 ⟹ ENSRNOP00000090771 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001134727 ⟹ NP_001128199 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006252311 ⟹ XP_006252373 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006252312 ⟹ XP_006252374 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006252313 ⟹ XP_006252375 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006252315 ⟹ XP_006252377 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008770896 ⟹ XP_008769118 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017599784 ⟹ XP_017455273 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039093606 ⟹ XP_038949534 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063274584 ⟹ XP_063130654 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063274585 ⟹ XP_063130655 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063274586 ⟹ XP_063130656 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001128199 | (Get FASTA) | NCBI Sequence Viewer |
XP_006252373 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006252374 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006252375 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006252377 | (Get FASTA) | NCBI Sequence Viewer | |
XP_008769118 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017455273 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038949534 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130654 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130655 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063130656 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAI66585 | (Get FASTA) | NCBI Sequence Viewer |
EDM02283 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000047801 | ||
ENSRNOP00000047801.3 | |||
ENSRNOP00000076612 | |||
ENSRNOP00000076612.1 | |||
ENSRNOP00000089380 | |||
ENSRNOP00000089380.1 | |||
ENSRNOP00000090771 | |||
ENSRNOP00000090771.1 |
RefSeq Acc Id: | NP_001128199 ⟸ NM_001134727 |
- UniProtKB: | B2GV98 (UniProtKB/TrEMBL), A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006252374 ⟸ XM_006252312 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8I6AAA9 (UniProtKB/TrEMBL), A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006252377 ⟸ XM_006252315 |
- Peptide Label: | isoform X10 |
- UniProtKB: | A0A8I5Y080 (UniProtKB/TrEMBL), A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006252373 ⟸ XM_006252311 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006252375 ⟸ XM_006252313 |
- Peptide Label: | isoform X5 |
- UniProtKB: | A0A8I6ABL3 (UniProtKB/TrEMBL), A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008769118 ⟸ XM_008770896 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017455273 ⟸ XM_017599784 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A6HTS0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000047801 ⟸ ENSRNOT00000047192 |
RefSeq Acc Id: | XP_038949534 ⟸ XM_039093606 |
- Peptide Label: | isoform X9 |
RefSeq Acc Id: | ENSRNOP00000076612 ⟸ ENSRNOT00000097640 |
RefSeq Acc Id: | ENSRNOP00000090771 ⟸ ENSRNOT00000108815 |
RefSeq Acc Id: | ENSRNOP00000089380 ⟸ ENSRNOT00000108157 |
RefSeq Acc Id: | XP_063130655 ⟸ XM_063274585 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_063130656 ⟸ XM_063274586 |
- Peptide Label: | isoform X8 |
RefSeq Acc Id: | XP_063130654 ⟸ XM_063274584 |
- Peptide Label: | isoform X6 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-B2GV98-F1-model_v2 | AlphaFold | B2GV98 | 1-677 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699827 | ||||||||
Promoter ID: | EPDNEW_R10351 | ||||||||
Type: | initiation region | ||||||||
Name: | Lrch1_1 | ||||||||
Description: | leucine rich repeats and calponin homology domain containing1 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1595678 | AgrOrtholog |
BioCyc Gene | G2FUF-13143 | BioCyc |
Ensembl Genes | ENSRNOG00000009412 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000047192 | ENTREZGENE |
ENSRNOT00000047192.4 | UniProtKB/TrEMBL | |
ENSRNOT00000097640.1 | UniProtKB/TrEMBL | |
ENSRNOT00000108157.1 | UniProtKB/TrEMBL | |
ENSRNOT00000108815.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.10.418.10 | UniProtKB/TrEMBL |
3.80.10.10 | UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7444640 | IMAGE-MGC_LOAD |
InterPro | Calponin-like_dom_sf | UniProtKB/TrEMBL |
CH-domain | UniProtKB/TrEMBL | |
L_dom-like | UniProtKB/TrEMBL | |
Leu-rich_rpt | UniProtKB/TrEMBL | |
Leu-rich_rpt_typical-subtyp | UniProtKB/TrEMBL | |
KEGG Report | rno:502020 | UniProtKB/TrEMBL |
MGC_CLONE | MGC:188329 | IMAGE-MGC_LOAD |
NCBI Gene | 502020 | ENTREZGENE |
PANTHER | CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN | UniProtKB/TrEMBL |
PTHR48051 | UniProtKB/TrEMBL | |
Pfam | LRR_8 | UniProtKB/TrEMBL |
PF00307 | UniProtKB/TrEMBL | |
PhenoGen | Lrch1 | PhenoGen |
PROSITE | LRR | UniProtKB/TrEMBL |
PS50021 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000009412 | RatGTEx |
SMART | LRR_BAC | UniProtKB/TrEMBL |
LRR_TYP | UniProtKB/TrEMBL | |
SM00033 | UniProtKB/TrEMBL | |
Superfamily-SCOP | Calponin-homology | UniProtKB/TrEMBL |
L domain-like | UniProtKB/TrEMBL | |
UniProt | A0A8I5Y080 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6AAA9 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6ABL3 | ENTREZGENE, UniProtKB/TrEMBL | |
A6HTS0 | ENTREZGENE, UniProtKB/TrEMBL | |
B2GV98 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2016-06-15 | Lrch1 | leucine rich repeats and calponin homology domain containing 1 | Lrch1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-05 | Lrch1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | LOC502020 | similar to Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2006-11-20 | LOC502020 | similar to Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |