Lrch1 (leucine rich repeats and calponin homology domain containing 1) - Rat Genome Database

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Gene: Lrch1 (leucine rich repeats and calponin homology domain containing 1) Rattus norvegicus
Analyze
Symbol: Lrch1
Name: leucine rich repeats and calponin homology domain containing 1
RGD ID: 1595678
Description: Predicted to be involved in cellular response to chemokine; negative regulation of GTPase activity; and negative regulation of T cell migration. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human LRCH1 (leucine rich repeats and calponin homology domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: leucine-rich repeat and calponin homology domain-containing protein 1; leucine-rich repeats and calponin homology (CH) domain containing 1; LOC502020; similar to Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81556,469,403 - 56,659,201 (-)NCBIGRCr8
GRCr8 Ensembl1556,481,395 - 56,659,100 (-)EnsemblGRCr8 Ensembl
mRatBN7.21550,070,605 - 50,249,724 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,071,947 - 50,249,657 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1554,222,543 - 54,400,257 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01555,334,112 - 55,518,558 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01552,173,550 - 52,351,346 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01556,778,738 - 56,970,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1556,785,162 - 56,970,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01560,506,225 - 60,691,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41555,585,038 - 55,788,456 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1549,704,864 - 49,882,665 (-)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:28028151   PMID:32631435  


Genomics

Comparative Map Data
Lrch1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81556,469,403 - 56,659,201 (-)NCBIGRCr8
GRCr8 Ensembl1556,481,395 - 56,659,100 (-)EnsemblGRCr8 Ensembl
mRatBN7.21550,070,605 - 50,249,724 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,071,947 - 50,249,657 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1554,222,543 - 54,400,257 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01555,334,112 - 55,518,558 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01552,173,550 - 52,351,346 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01556,778,738 - 56,970,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1556,785,162 - 56,970,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01560,506,225 - 60,691,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41555,585,038 - 55,788,456 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1549,704,864 - 49,882,665 (-)NCBICelera
Cytogenetic Map15q11NCBI
LRCH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381346,553,170 - 46,753,041 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1346,553,168 - 46,753,040 (+)EnsemblGRCh38hg38GRCh38
GRCh371347,127,305 - 47,327,176 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361346,025,304 - 46,215,731 (+)NCBINCBI36Build 36hg18NCBI36
Build 341346,025,303 - 46,215,731NCBI
Celera1328,183,132 - 28,383,118 (+)NCBICelera
Cytogenetic Map13q14.13-q14.2NCBI
HuRef1327,920,806 - 28,120,759 (+)NCBIHuRef
CHM1_11347,094,831 - 47,294,960 (+)NCBICHM1_1
T2T-CHM13v2.01345,774,368 - 45,974,291 (+)NCBIT2T-CHM13v2.0
Lrch1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391474,992,113 - 75,185,447 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1474,992,115 - 75,185,316 (-)EnsemblGRCm39 Ensembl
GRCm381474,754,673 - 74,948,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1474,754,675 - 74,947,876 (-)EnsemblGRCm38mm10GRCm38
MGSCv371475,154,480 - 75,347,684 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361473,488,572 - 73,682,163 (-)NCBIMGSCv36mm8
Celera1472,262,033 - 72,448,041 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1439.39NCBI
Lrch1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955431404,708 - 498,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955431404,575 - 501,268 (+)NCBIChiLan1.0ChiLan1.0
LRCH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21447,993,450 - 48,197,337 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11346,644,563 - 46,848,369 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01327,697,684 - 27,897,762 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11346,415,745 - 46,615,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1346,416,017 - 46,613,065 (+)Ensemblpanpan1.1panPan2
LRCH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1224,576,658 - 4,687,621 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl224,578,733 - 4,771,753 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha224,621,183 - 4,833,490 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0224,689,020 - 4,771,953 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl224,691,433 - 4,897,648 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1224,473,616 - 4,679,687 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0224,537,280 - 4,743,239 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0224,541,864 - 4,747,977 (-)NCBIUU_Cfam_GSD_1.0
Lrch1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945156,609,736 - 156,796,142 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493656593,779 - 277,777 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493656593,791 - 280,192 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRCH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1120,688,596 - 20,906,608 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11120,687,657 - 20,906,743 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21121,028,825 - 21,143,457 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRCH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1324,545,641 - 24,748,992 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605719,248,894 - 19,451,885 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrch1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247488,305,147 - 8,480,025 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247488,294,112 - 8,479,933 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lrch1
1212 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:81
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000047192
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
7411725Strs7Sensitivity to stroke QTL 73.8cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)154446544756583797Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
D15Rat46  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,209,257 - 50,209,472 (+)MAPPERmRatBN7.2
Rnor_6.01556,929,803 - 56,930,017NCBIRnor6.0
Rnor_5.01560,651,035 - 60,651,249UniSTSRnor5.0
RGSC_v3.41555,722,367 - 55,722,582RGDRGSC3.4
RGSC_v3.41555,722,368 - 55,722,582UniSTSRGSC3.4
Celera1549,842,267 - 49,842,481UniSTS
RGSC_v3.11555,738,147 - 55,738,362RGD
SHRSP x BN Map1534.6299RGD
SHRSP x BN Map1534.6299UniSTS
Cytogenetic Map15q11UniSTS
RH132838  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,078,040 - 50,078,258 (+)MAPPERmRatBN7.2
Rnor_6.01556,791,255 - 56,791,472NCBIRnor6.0
Rnor_5.01560,513,660 - 60,513,877UniSTSRnor5.0
RGSC_v3.41555,591,133 - 55,591,350UniSTSRGSC3.4
Celera1549,710,959 - 49,711,176UniSTS
Cytogenetic Map15q11UniSTS
RH130207  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,072,058 - 50,072,243 (+)MAPPERmRatBN7.2
Rnor_6.01556,785,274 - 56,785,458NCBIRnor6.0
Rnor_5.01560,507,679 - 60,507,863UniSTSRnor5.0
RGSC_v3.41555,585,152 - 55,585,336UniSTSRGSC3.4
Celera1549,704,978 - 49,705,162UniSTS
Cytogenetic Map15q11UniSTS
RH137621  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81556,488,929 - 56,489,088 (+)Marker Load Pipeline
mRatBN7.21550,079,480 - 50,079,639 (+)MAPPERmRatBN7.2
Rnor_6.01556,792,695 - 56,792,853NCBIRnor6.0
Rnor_5.01560,515,100 - 60,515,258UniSTSRnor5.0
RGSC_v3.41555,592,573 - 55,592,731UniSTSRGSC3.4
Celera1549,712,399 - 49,712,557UniSTS
Cytogenetic Map15q11UniSTS
BF390346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,079,992 - 50,080,158 (+)MAPPERmRatBN7.2
Rnor_6.01556,793,207 - 56,793,372NCBIRnor6.0
Rnor_5.01560,515,612 - 60,515,777UniSTSRnor5.0
RGSC_v3.41555,593,085 - 55,593,250UniSTSRGSC3.4
Celera1549,712,911 - 49,713,076UniSTS
Cytogenetic Map15q11UniSTS
D10Bir6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,170,858 - 50,170,974 (+)MAPPERmRatBN7.2
Rnor_6.01556,891,420 - 56,891,535NCBIRnor6.0
Rnor_5.01560,613,475 - 60,613,590UniSTSRnor5.0
RGSC_v3.41555,683,934 - 55,684,049UniSTSRGSC3.4
RGSC_v3.42253,107,044 - 253,108,439UniSTSRGSC3.4
Celera1549,803,842 - 49,803,957UniSTS
Cytogenetic Map15q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000047192   ⟹   ENSRNOP00000047801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1556,489,804 - 56,659,100 (-)Ensembl
mRatBN7.2 Ensembl1550,071,947 - 50,249,657 (-)Ensembl
Rnor_6.0 Ensembl1556,785,162 - 56,970,365 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097640   ⟹   ENSRNOP00000076612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1556,481,395 - 56,659,100 (-)Ensembl
mRatBN7.2 Ensembl1550,071,947 - 50,249,657 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108157   ⟹   ENSRNOP00000089380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1556,489,804 - 56,659,100 (-)Ensembl
mRatBN7.2 Ensembl1550,080,927 - 50,249,657 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108815   ⟹   ENSRNOP00000090771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1556,481,395 - 56,659,100 (-)Ensembl
mRatBN7.2 Ensembl1550,071,947 - 50,249,657 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000157266   ⟹   ENSRNOP00000103277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1556,489,804 - 56,659,100 (-)Ensembl
RefSeq Acc Id: NM_001134727   ⟹   NP_001128199
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,481,393 - 56,659,100 (-)NCBI
mRatBN7.21550,071,945 - 50,249,657 (-)NCBI
Rnor_6.01556,785,160 - 56,970,365 (-)NCBI
Rnor_5.01560,506,225 - 60,691,636 (-)NCBI
RGSC_v3.41555,585,038 - 55,788,456 (-)RGD
Celera1549,704,864 - 49,882,665 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252311   ⟹   XP_006252373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,482,902 - 56,659,195 (-)NCBI
mRatBN7.21550,077,975 - 50,249,723 (-)NCBI
Rnor_6.01556,792,653 - 56,970,437 (-)NCBI
Rnor_5.01560,506,225 - 60,691,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252312   ⟹   XP_006252374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,480,053 - 56,659,177 (-)NCBI
mRatBN7.21550,070,605 - 50,249,721 (-)NCBI
Rnor_6.01556,783,820 - 56,970,433 (-)NCBI
Rnor_5.01560,506,225 - 60,691,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252313   ⟹   XP_006252375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,482,902 - 56,659,178 (-)NCBI
mRatBN7.21550,077,975 - 50,249,722 (-)NCBI
Rnor_6.01556,792,653 - 56,970,435 (-)NCBI
Rnor_5.01560,506,225 - 60,691,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252315   ⟹   XP_006252377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,480,053 - 56,659,177 (-)NCBI
mRatBN7.21550,070,605 - 50,249,721 (-)NCBI
Rnor_6.01556,783,820 - 56,970,433 (-)NCBI
Rnor_5.01560,506,225 - 60,691,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770896   ⟹   XP_008769118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,482,902 - 56,659,201 (-)NCBI
mRatBN7.21550,077,975 - 50,249,724 (-)NCBI
Rnor_6.01556,792,653 - 56,970,439 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599784   ⟹   XP_017455273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,496,541 - 56,659,186 (-)NCBI
mRatBN7.21550,081,569 - 50,249,723 (-)NCBI
Rnor_6.01556,796,024 - 56,970,436 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093606   ⟹   XP_038949534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,482,902 - 56,574,620 (-)NCBI
mRatBN7.21550,077,975 - 50,165,161 (-)NCBI
RefSeq Acc Id: XM_063274584   ⟹   XP_063130654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,496,541 - 56,659,176 (-)NCBI
RefSeq Acc Id: XM_063274585   ⟹   XP_063130655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,469,403 - 56,659,176 (-)NCBI
RefSeq Acc Id: XM_063274586   ⟹   XP_063130656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,482,902 - 56,628,139 (-)NCBI
RefSeq Acc Id: NP_001128199   ⟸   NM_001134727
- UniProtKB: B2GV98 (UniProtKB/TrEMBL),   A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252374   ⟸   XM_006252312
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AAA9 (UniProtKB/TrEMBL),   A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252377   ⟸   XM_006252315
- Peptide Label: isoform X10
- UniProtKB: A0A8I5Y080 (UniProtKB/TrEMBL),   A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252373   ⟸   XM_006252311
- Peptide Label: isoform X1
- UniProtKB: A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252375   ⟸   XM_006252313
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ABL3 (UniProtKB/TrEMBL),   A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769118   ⟸   XM_008770896
- Peptide Label: isoform X2
- UniProtKB: A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455273   ⟸   XM_017599784
- Peptide Label: isoform X4
- UniProtKB: A6HTS0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047801   ⟸   ENSRNOT00000047192
RefSeq Acc Id: XP_038949534   ⟸   XM_039093606
- Peptide Label: isoform X9
Ensembl Acc Id: ENSRNOP00000076612   ⟸   ENSRNOT00000097640
Ensembl Acc Id: ENSRNOP00000090771   ⟸   ENSRNOT00000108815
Ensembl Acc Id: ENSRNOP00000089380   ⟸   ENSRNOT00000108157
RefSeq Acc Id: XP_063130655   ⟸   XM_063274585
- Peptide Label: isoform X7
- UniProtKB: A6HTS0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130656   ⟸   XM_063274586
- Peptide Label: isoform X8
- UniProtKB: A6HTS0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130654   ⟸   XM_063274584
- Peptide Label: isoform X6
- UniProtKB: A6HTS0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103277   ⟸   ENSRNOT00000157266
Protein Domains
Calponin-homology (CH)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GV98-F1-model_v2 AlphaFold B2GV98 1-677 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699827
Promoter ID:EPDNEW_R10351
Type:initiation region
Name:Lrch1_1
Description:leucine rich repeats and calponin homology domain containing1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01556,970,409 - 56,970,469EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595678 AgrOrtholog
BioCyc Gene G2FUF-13143 BioCyc
Ensembl Genes ENSRNOG00000009412 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047192 ENTREZGENE
  ENSRNOT00000047192.4 UniProtKB/TrEMBL
  ENSRNOT00000097640 ENTREZGENE
  ENSRNOT00000097640.1 UniProtKB/TrEMBL
  ENSRNOT00000108157 ENTREZGENE
  ENSRNOT00000108157.1 UniProtKB/TrEMBL
  ENSRNOT00000108815 ENTREZGENE
  ENSRNOT00000108815.1 UniProtKB/TrEMBL
  ENSRNOT00000157266 ENTREZGENE
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7444640 IMAGE-MGC_LOAD
InterPro Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_domain-containing UniProtKB/TrEMBL
KEGG Report rno:502020 UniProtKB/TrEMBL
MGC_CLONE MGC:188329 IMAGE-MGC_LOAD
NCBI Gene 502020 ENTREZGENE
PANTHER LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 1 UniProtKB/TrEMBL
  PTHR48051 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PhenoGen Lrch1 PhenoGen
PROSITE LRR UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009412 RatGTEx
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
UniProt A0A8I5Y080 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAA9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABL3 ENTREZGENE, UniProtKB/TrEMBL
  A6HTS0 ENTREZGENE, UniProtKB/TrEMBL
  B2GV98 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Lrch1  leucine rich repeats and calponin homology domain containing 1  Lrch1  leucine-rich repeats and calponin homology (CH) domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Lrch1  leucine-rich repeats and calponin homology (CH) domain containing 1  LOC502020  similar to Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC502020  similar to Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1)      Symbol and Name status set to provisional 70820 PROVISIONAL