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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lyase activity
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Accession:GO:0051350 term browser browse the term
Definition:Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Synonyms:exact_synonym: down regulation of lyase activity;   downregulation of lyase activity;   lyase inhibitor
 narrow_synonym: inhibition of lyase activity



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negative regulation of lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:20110805), (PMID:20501872) RGD PMID:20110805 PMID:20501872 NCBI chr 3:8,392,926...8,394,325 JBrowse link
negative regulation of aconitate hydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
negative regulation of adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO
IBA
(MGI:6212875|PMID:24962568)
PMID:21873635
RGD PMID:24962568 PMID:21873635 MGI:6212875, RGD:13792537 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
JBrowse link
G Akap5 A-kinase anchoring protein 5 involved_in IDA
ISO
PMID:22976297
(PMID:20410303), (PMID:21771783)
RGD PMID:20410303 PMID:21771783 PMID:20410303 PMID:22976297 RGD:7242424, RGD:13800547 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP RGD PMID:19574217 RGD:6902943 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Akap9 A-kinase anchoring protein 9 IMP RGD PMID:18772391 RGD:2313147 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO
IBA
(PMID:2531656)
PMID:21873635
RGD PMID:2531656 PMID:21873635 RGD:13792537 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IMP RGD PMID:15147298 RGD:2315493 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Galr1 galanin receptor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:75,772,021...75,787,577
Ensembl chr18:75,772,023...75,787,577
JBrowse link
G Galr2 galanin receptor 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Galr3 galanin receptor 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685
JBrowse link
G Gpr87 G protein-coupled receptor 87 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:10869375 RGD:632981 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:8702617 RGD:1601497 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G P2ry13 purinergic receptor P2Y13 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:143,470,437...143,476,360
Ensembl chr 2:143,470,425...143,473,434
JBrowse link
G Palm paralemmin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3618440|PMID:16386234)
RGD PMID:16386234 PMID:21873635 MGI:3618440, RGD:13792537 NCBI chr 7:9,886,634...9,912,389
Ensembl chr 7:9,886,643...9,912,555
JBrowse link
negative regulation of cystathionine beta-synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:24416422) RGD PMID:24416422 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Pdzd3 PDZ domain containing 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:44,584,390...44,588,838
Ensembl chr 8:44,584,390...44,588,860
JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(MGI:5810226|PMID:27471269)
RGD PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    biological regulation 13380
      regulation of molecular function 3136
        negative regulation of molecular function 1244
          negative regulation of catalytic activity 820
            negative regulation of lyase activity 21
              negative regulation of L-dopa decarboxylase activity 0
              negative regulation of aconitate hydratase activity 1
              negative regulation of adenylate cyclase activity 15
              negative regulation of cystathionine beta-synthase activity 1
              negative regulation of guanylate cyclase activity 3
paths to the root