Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphatase activity
go back to main search page
Accession:GO:0010923 term browser browse the term
Definition:Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.


show annotations for term's descendants           Sort by:
 
negative regulation of phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07051376.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:10593895)
UniProt
RGD
PMID:10593895 GO_REF:0000024 NCBI chr 3:106,536,009...106,571,255 JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin involved_in ISO (PMID:18617530) RGD PMID:18617530 NCBI chr 1:5,727,111...5,845,338 JBrowse link
G Ppp1r35 protein phosphatase 1, regulatory subunit 35 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:18,915,909...18,919,253 JBrowse link
G Ppp1r36 protein phosphatase 1, regulatory subunit 36 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:95,138,526...95,159,102 JBrowse link
G Tmem225 transmembrane protein 225 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:40,497,483...40,500,041 JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in IBA
ISO
PMID:21873635
(PMID:17936702)
RGD PMID:17936702, PMID:21873635 RGD:13792537 NCBI chr 1:90,646,392...90,704,811 JBrowse link
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:52,234,089...52,271,568 JBrowse link
G Hpn hepsin acts_upstream_of_or_within ISO MGI:3575149 (MGI:5437809|PMID:22912808) RGD PMID:22912808 MGI:5437809 NCBI chr 1:86,337,085...86,352,785 JBrowse link
G Sema4d semaphorin 4D involved_in IBA
ISO
PMID:21873635
(MGI:5297297|PMID:22019888)
(PMID:22019888)
RGD PMID:22019888, PMID:21873635 MGI:5297297, RGD:13792537 NCBI chr17:13,430,324...13,537,146 JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:18358889)
AgBase
RGD
PMID:18358889 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771 JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:5285024|PMID:21689636) RGD PMID:21689636 MGI:5285024 NCBI chr20:3,622,011...3,624,629 JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
ISO
GO_REF:0000107
(PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr16:69,319,487...69,373,251 JBrowse link
G Mprip myosin phosphatase Rho interacting protein IMP RGD PMID:17661354 RGD:9685557 NCBI chr10:44,453,929...44,569,442 JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(PMID:16417406)
UniProt
RGD
PMID:16417406 GO_REF:0000024 NCBI chr 7:134,577,443...134,622,934 JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
UniProtKB:O75116 (PMID:25816133)
GO_REF:0000107
RGD
Ensembl
PMID:25816133 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345 JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033 JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:3,622,011...3,624,629 JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034 JBrowse link
negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr16:66,288,678...66,305,893 JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in IBA
ISO
PMID:21873635
(PMID:24157919)
RGD PMID:24157919, PMID:21873635 RGD:13792537 NCBI chr10:15,993,454...15,999,795 JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:69,108,483...69,163,255 JBrowse link
G Cmya5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:24,279,520...24,378,253 JBrowse link
G Cry2 cryptochrome circadian regulator 2 involved_in ISO
IEA
(PMID:9383998)
GO_REF:0000107
RGD
Ensembl
PMID:9383998 GO_REF:0000107 NCBI chr 3:78,374,995...78,405,001 JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 3:140,040,359...140,060,107 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B involved_in ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 6:27,832,128...27,850,600 JBrowse link
G Mastl microtubule associated serine/threonine kinase-like involved_in ISO (PMID:20538976) RGD PMID:20538976 NCBI chr17:85,250,512...85,287,479 JBrowse link
G Ppia peptidylprolyl isomerase A IDA RGD PMID:19832699 RGD:7247324 NCBI chr14:81,279,292...81,282,960 JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:1,601,350...1,604,857 JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:11564868) RGD PMID:11564868 NCBI chr 1:96,000,053...96,003,128 JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B involved_in ISO (PMID:10807923) RGD PMID:10807923 NCBI chr10:83,347,731...83,356,775 JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IDA
IMP
RGD PMID:12016225, PMID:10585469 RGD:625568, RGD:9999389 NCBI chr10:79,938,055...79,954,085 JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:18715871)
RGD PMID:18715871, PMID:21873635 RGD:13792537 NCBI chr 6:122,663,172...122,753,988 JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator involved_in ISO (PMID:16916641) RGD PMID:16916641 NCBI chr 3:13,689,742...13,720,287 JBrowse link
G Rgn regucalcin IMP RGD PMID:10922512 RGD:9590172 NCBI chr  X:1,619,030...1,634,456 JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO (PMID:24709986) RGD PMID:24709986 NCBI chr12:20,907,410...20,940,232 JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO (PMID:17384681) RGD PMID:17384681 NCBI chr13:77,527,176...77,552,026 JBrowse link
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D involved_in ISO
ISS
(PMID:12974676)
GO_REF:0000024
RGD
UniProt
PMID:12974676 GO_REF:0000024 NCBI chr 3:106,205,043...106,219,290 JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11500506 RGD:13508599 NCBI chr 8:108,288,401...108,309,009 JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase involved_in ISO (PMID:24846175) RGD PMID:24846175 NCBI chr13:38,675,776...38,959,697 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of molecular function 3070
        regulation of catalytic activity 2372
          negative regulation of catalytic activity 798
            negative regulation of hydrolase activity 414
              negative regulation of phosphatase activity 39
                negative regulation of alkaline phosphatase activity 5
                negative regulation of phosphatidate phosphatase activity 1
                negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1
                negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0
                negative regulation of phosphoprotein phosphatase activity + 26
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of cellular metabolic process 5945
            regulation of phosphorus metabolic process 1476
              regulation of phosphate metabolic process 1475
                regulation of dephosphorylation 134
                  regulation of phosphatase activity 87
                    negative regulation of phosphatase activity 39
                      negative regulation of alkaline phosphatase activity 5
                      negative regulation of phosphatidate phosphatase activity 1
                      negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 1
                      negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0
                      negative regulation of phosphoprotein phosphatase activity + 26
paths to the root