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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of nuclease activity
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Accession:GO:0032074 term browser browse the term
Definition:Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: down regulation of nuclease activity;   downregulation of nuclease activity
 narrow_synonym: inhibition of nuclease activity
 related_synonym: nuclease inhibitor


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negative regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 involved_in ISO (PMID:17611195) RGD PMID:17611195 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) RGD PMID:19944011 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
negative regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 involved_in ISO (PMID:7539425) RGD PMID:7539425 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA		 (PMID:19328063)
(MGI:3840374|PMID:19328063)
PMID:21873635		 RGD PMID:19328063 PMID:21873635 MGI:3840374, RGD:13792537 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
negative regulation of exonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:15200954)
PMID:21873635		 RGD PMID:15200954 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15200954) RGD PMID:15200954 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    metabolic process 12347
      regulation of metabolic process 7015
        regulation of macromolecule metabolic process 6491
          regulation of nuclease activity 30
            negative regulation of nuclease activity 7
              negative regulation of deoxyribonuclease activity + 2
              negative regulation of exonuclease activity + 2
              negative regulation of ribonuclease activity + 2
Path 2
Term Annotations click to browse term
  biological_process 20094
    metabolic process 12347
      cellular metabolic process 10465
        cellular aromatic compound metabolic process 6024
          nucleobase-containing compound metabolic process 5784
            regulation of nucleobase-containing compound metabolic process 4039
              negative regulation of nucleobase-containing compound metabolic process 1584
                negative regulation of nuclease activity 7
                  negative regulation of deoxyribonuclease activity + 2
                  negative regulation of exonuclease activity + 2
                  negative regulation of ribonuclease activity + 2
paths to the root