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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of nuclease activity
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Accession:GO:0032074 term browser browse the term
Definition:Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:exact_synonym: down regulation of nuclease activity;   downregulation of nuclease activity
 narrow_synonym: inhibition of nuclease activity
 related_synonym: nuclease inhibitor

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negative regulation of nuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 involved_in ISO (PMID:17611195) RGD PMID:17611195 NCBI chr 8:61,817,258...61,824,023
Ensembl chr 8:61,817,258...61,823,102 		JBrowse link
negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) RGD PMID:19944011 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821 		JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458 		JBrowse link
negative regulation of endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 involved_in ISO (PMID:7539425) RGD PMID:7539425 NCBI chr19:31,867,960...31,892,863
Ensembl chr19:31,867,981...31,892,863 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:19328063)
(MGI:3840374|PMID:19328063)		 RGD PMID:19328063 MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989 		JBrowse link
negative regulation of exonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:15200954)
PMID:21873635		 RGD PMID:15200954, PMID:21873635 RGD:13792537 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15200954) RGD PMID:15200954 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11881
      regulation of metabolic process 6807
        regulation of macromolecule metabolic process 6319
          regulation of nuclease activity 30
            negative regulation of nuclease activity 7
              negative regulation of deoxyribonuclease activity + 2
              negative regulation of exonuclease activity + 2
              negative regulation of ribonuclease activity + 2
Path 2
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11881
      cellular metabolic process 10838
        cellular aromatic compound metabolic process 5627
          nucleobase-containing compound metabolic process 5410
            regulation of nucleobase-containing compound metabolic process 3830
              negative regulation of nucleobase-containing compound metabolic process 1552
                negative regulation of nuclease activity 7
                  negative regulation of deoxyribonuclease activity + 2
                  negative regulation of exonuclease activity + 2
                  negative regulation of ribonuclease activity + 2
paths to the root