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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transferase activity
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Accession:GO:0051348 term browser browse the term
Definition:Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
Comment:This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
Synonyms:exact_synonym: down regulation of transferase activity;   downregulation of transferase activity;   transferase inhibitor
 narrow_synonym: inhibition of transferase activity



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negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IDA RGD PMID:10721722 RGD:632478 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IDA RGD PMID:10721722 RGD:632478 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:22584582 RGD:10045364 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gckr glucokinase regulator IDA RGD PMID:14627435 RGD:1598592 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IMP RGD PMID:12064607 RGD:1299562 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
negative regulation of kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase IDA RGD PMID:10411542 RGD:5134371 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:19762078 RGD:150429972 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 IDA RGD PMID:9366267 RGD:5134981 NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 IDA due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:17182785 RGD:2301767 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Kng2 kininogen 2 IDA in ConA- or PHA-stimulated Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IDA RGD PMID:9857190 RGD:10044039 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:14612383 RGD:1580517 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:17289031 RGD:9587773 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Drd1 dopamine receptor D1 IMP RGD PMID:12688394 RGD:1581394 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd5 dopamine receptor D5 IMP RGD PMID:12688394 RGD:1581394 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IMP RGD PMID:21668448 RGD:10401931 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Il6 interleukin 6 IDA Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilk integrin-linked kinase IMP GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Pcp4 Purkinje cell protein 4 IDA RGD PMID:10751438 RGD:1579763 NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha TAS RGD PMID:1491692 RGD:729428 NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282
JBrowse link
G Rgn regucalcin IMP RGD PMID:11455566 RGD:9590207 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:16556873 RGD:1580657 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link

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Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of molecular function 323
        negative regulation of molecular function 126
          negative regulation of catalytic activity 75
            negative regulation of transferase activity 25
              negative regulation of ATP citrate synthase activity 0
              negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity 0
              negative regulation of CoA-transferase activity 0
              negative regulation of DNA primase activity 0
              negative regulation of DNA-directed DNA polymerase activity 0
              negative regulation of NAD+ ADP-ribosyltransferase activity 0
              negative regulation of RNA polymerase III activity 0
              negative regulation of RNA-dependent RNA polymerase activity 0
              negative regulation of SUMO transferase activity 0
              negative regulation of alpha-(1->3)-fucosyltransferase activity 0
              negative regulation of choline O-acetyltransferase activity 0
              negative regulation of glucuronosyltransferase activity 0
              negative regulation of glycogen (starch) synthase activity 0
              negative regulation of glycogen synthase activity, transferring glucose-1-phosphate 0
              negative regulation of kinase activity + 24
              negative regulation of polynucleotide adenylyltransferase activity 0
              negative regulation of protein ADP-ribosylation 0
              negative regulation of protein-glutamine gamma-glutamyltransferase activity 0
              negative regulation of pyruvate kinase activity 0
              negative regulation of serine C-palmitoyltransferase activity 0
              negative regulation of telomerase activity + 1
              negative regulation of ubiquitin-protein transferase activity + 0
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