Ubash3b (ubiquitin associated and SH3 domain containing, B)

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Gene: Ubash3b (ubiquitin associated and SH3 domain containing, B) Rattus norvegicus

Analyze

Symbol:

Ubash3b

Name:

ubiquitin associated and SH3 domain containing, B

RGD ID:

1310357

Description:

Enables ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including collagen-activated tyrosine kinase receptor signaling pathway; negative regulation of bone resorption; and platelet aggregation. Predicted to act upstream of or within several processes, including negative regulation of osteoclast differentiation; negative regulation of platelet aggregation; and platelet activation. Predicted to be active in cytoplasm. Orthologous to human UBASH3B (ubiquitin associated and SH3 domain containing B); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Cbl-interacting protein Sts-1; LOC315579; RGD1310357; similar to RIKEN cDNA 2810457I06; Sts-1; Sts1; ubiquitin-associated and SH3 domain-containing protein B

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	41,385,419 - 41,532,248 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	41,388,341 - 41,532,201 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	46,882,006 - 47,025,074 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	45,160,614 - 45,303,702 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	43,028,175 - 43,171,244 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	45,224,053 - 45,375,450 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	45,223,992 - 45,375,435 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	43,702,541 - 43,853,864 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	43,992,862 - 44,135,847 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	44,001,003 - 44,067,551 (-)	NCBI
Celera	8	40,986,547 - 41,129,756 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chromosome 11, Partial Trisomy 11q (ISO)

Dwarfism (ISO)

genetic disease (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,3-dinitrobenzene (EXP)

1-nitropyrene (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP)

carbamazepine (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

cisplatin (EXP,ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP,ISO)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dioxygen (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fulvestrant (ISO)

gentamycin (EXP)

ivermectin (ISO)

lead diacetate (ISO)

lead(0) (ISO)

leflunomide (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nickel atom (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (ISO)

progesterone (ISO)

propanal (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

testosterone (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

tunicamycin (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

collagen-activated signaling pathway (ISO)

collagen-activated tyrosine kinase receptor signaling pathway (IBA,ISO)

negative regulation of bone resorption (IBA,ISO)

negative regulation of osteoclast differentiation (ISO)

negative regulation of platelet aggregation (ISO)

negative regulation of signal transduction (IBA,ISO)

platelet activation (ISO)

platelet aggregation (IBA,ISO)

regulation of osteoclast differentiation (IBA,ISO)

regulation of release of sequestered calcium ion into cytosol (IBA,ISO)

signal transduction (ISO)

Cellular Component

cytoplasm (IBA)

Molecular Function

identical protein binding (ISO)

phosphoprotein binding (ISO)

protein binding (ISO)

protein tyrosine phosphatase activity (IBA,ISO)

ubiquitin protein ligase binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway.	Peruzzi G, etal., J Immunol. 2007 Aug 15;179(4):2089-96.
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:20585042	PMID:23149425	PMID:25416956	PMID:27609517

Genomics

Comparative Map Data

Ubash3b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	41,385,419 - 41,532,248 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	41,388,341 - 41,532,201 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	46,882,006 - 47,025,074 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	45,160,614 - 45,303,702 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	43,028,175 - 43,171,244 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	45,224,053 - 45,375,450 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	45,223,992 - 45,375,435 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	43,702,541 - 43,853,864 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	43,992,862 - 44,135,847 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	44,001,003 - 44,067,551 (-)	NCBI
Celera	8	40,986,547 - 41,129,756 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

UBASH3B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	122,655,722 - 122,814,473 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	122,655,722 - 122,814,473 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	122,526,430 - 122,685,181 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	122,031,640 - 122,190,391 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	119,685,695 - 119,844,497 (+)	NCBI		Celera
Cytogenetic Map	11	q24.1	NCBI
HuRef	11	118,468,875 - 118,627,622 (+)	NCBI		HuRef
CHM1_1	11	122,412,295 - 122,571,102 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	122,683,359 - 122,842,181 (+)	NCBI		T2T-CHM13v2.0

Ubash3b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	40,922,056 - 41,069,358 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	40,922,394 - 41,072,993 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	41,010,760 - 41,161,692 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	41,011,098 - 41,161,697 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	40,821,724 - 40,965,577 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	40,764,710 - 40,908,563 (-)	NCBI		MGSCv36	mm8
MGSCv36	9	41,219,202 - 41,364,403 (-)	NCBI		MGSCv36	mm8
Celera	9	38,241,137 - 38,383,815 (-)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	21.84	NCBI

Ubash3b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	23,518,240 - 23,667,697 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	23,518,851 - 23,667,617 (+)	NCBI	ChiLan1.0	ChiLan1.0

UBASH3B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	11	124,462,174 - 124,620,547 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	117,489,411 - 117,647,719 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	121,410,178 - 121,567,716 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	121,410,545 - 121,563,133 (+)	Ensembl	panpan1.1		panPan2

UBASH3B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	11,496,254 - 11,614,769 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	11,500,669 - 11,614,675 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	11,551,610 - 11,690,824 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	11,446,452 - 11,586,409 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	11,447,895 - 11,586,395 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	11,549,978 - 11,689,276 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	11,488,972 - 11,628,138 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	11,527,189 - 11,666,755 (-)	NCBI		UU_Cfam_GSD_1.0

Ubash3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	104,304,260 - 104,451,965 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	7,225,977 - 7,373,381 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936542	7,225,387 - 7,370,163 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBASH3B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	49,630,793 - 49,770,897 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	49,630,678 - 49,772,348 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	54,975,101 - 55,118,054 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBASH3B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	114,053,792 - 114,218,909 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	114,054,384 - 114,218,912 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	11,913,397 - 12,072,484 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ubash3b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624880	2,270,679 - 2,427,298 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624880	2,269,247 - 2,427,531 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ubash3b
1221 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	192
Count of miRNA genes:	132
Interacting mature miRNAs:	152
Transcripts:	ENSRNOT00000010873
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	2097640	47097640	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	2097640	47097640	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	2097640	47097640	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	2097640	47097640	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	4705810	49705810	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	4705810	49705810	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	4705810	49705810	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1558646	Swd5	Spike wave discharge measurement QTL 5	3.45	0.00036	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	8	14906751	59906751	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	16290444	61290444	Rat
631271	Lecl1	Lens clarity QTL 1		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	8	18984168	84531599	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	19331152	93965294	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	22662330	67662330	Rat
2303564	Gluco43	Glucose level QTL 43	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	26130187	71130187	Rat
2303572	Insul13	Insulin level QTL 13	2		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	8	26130187	71130187	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	26644912	46711092	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	27205715	54998217	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	27205715	99103503	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	27205715	99103503	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	27205715	99103503	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	28242912	53961020	Rat
1300146	Rf17	Renal function QTL 17	2.9		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	8	28242912	73242912	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	28242912	99525068	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	29502665	50095447	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	29502665	70386295	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	30188867	94457446	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	42692818	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	58482492	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	30848154	61290444	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	30848154	82460899	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	30848154	82460899	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	30848154	82460899	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	30848154	82460899	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	30848154	101699754	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	30848154	101699754	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	30848154	101699754	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30848259	105647037	Rat
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30856404	75856404	Rat
1582222	Epfw2	Epididymal fat weight QTL 2	3.2	0.0005	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	8	31737729	76737729	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	35551938	80551938	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	35582032	80582032	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	36469535	99083736	Rat
737824	Hcar10	Hepatocarcinoma resistance QTL 10	2.9		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	8	40713066	82925667	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	40713066	93965294	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat

Markers in Region

D8Rat188

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	41,435,262 - 41,435,385 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	45,272,853 - 45,272,975	NCBI	Rnor6.0
Rnor_5.0	8	43,751,341 - 43,751,463	UniSTS	Rnor5.0
RGSC_v3.4	8	44,039,525 - 44,039,648	RGD	RGSC3.4
RGSC_v3.4	8	44,039,526 - 44,039,648	UniSTS	RGSC3.4
RGSC_v3.1	8	44,048,291 - 44,048,414	RGD
Celera	8	41,032,972 - 41,033,094	UniSTS
SHRSP x BN Map	8	32.42	RGD
SHRSP x BN Map	8	32.42	UniSTS
Cytogenetic Map	8	q22	UniSTS

D8Got200

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	41,463,731 - 41,463,953 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	45,302,911 - 45,303,132	NCBI	Rnor6.0
Rnor_5.0	8	43,781,140 - 43,781,361	UniSTS	Rnor5.0
RGSC_v3.4	8	44,067,791 - 44,068,048	RGD	RGSC3.4
RGSC_v3.4	8	44,067,826 - 44,068,047	UniSTS	RGSC3.4
RGSC_v3.1	8	44,076,592 - 44,076,813	RGD
Celera	8	41,061,532 - 41,061,753	UniSTS
RH 3.4 Map	8	393.7	RGD
RH 3.4 Map	8	393.7	UniSTS
Cytogenetic Map	8	q22	UniSTS

RH129595

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	41,387,996 - 41,388,179 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	45,226,630 - 45,226,812	NCBI	Rnor6.0
Rnor_5.0	8	43,705,118 - 43,705,300	UniSTS	Rnor5.0
RGSC_v3.4	8	43,992,260 - 43,992,442	UniSTS	RGSC3.4
Celera	8	40,985,945 - 40,986,127	UniSTS
RH 3.4 Map	8	394.3	UniSTS
Cytogenetic Map	8	q22	UniSTS

AU049662

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	41,485,202 - 41,485,375 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	45,324,379 - 45,324,551	NCBI	Rnor6.0
Rnor_5.0	8	43,802,608 - 43,802,780	UniSTS	Rnor5.0
RGSC_v3.4	8	44,089,294 - 44,089,466	UniSTS	RGSC3.4
Celera	8	41,083,000 - 41,083,168	UniSTS
Cytogenetic Map	8	q22	UniSTS

UniSTS:236101

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	41,389,092 - 41,389,296 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	45,227,726 - 45,227,929	NCBI	Rnor6.0
Rnor_5.0	8	43,706,214 - 43,706,417	UniSTS	Rnor5.0
RGSC_v3.4	8	43,993,356 - 43,993,559	UniSTS	RGSC3.4
Celera	8	40,987,041 - 40,987,244	UniSTS
Cytogenetic Map	8	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		10	6	6	11	6			60	14	16	11
Low	3	33	51	35	8	35	8	9	14	21	25		8
Below cutoff								2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000198	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000010873 ⟹ ENSRNOP00000010873

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	41,388,341 - 41,532,201 (-)	Ensembl
Rnor_6.0 Ensembl	8	45,223,992 - 45,375,435 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102848 ⟹ ENSRNOP00000076960

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	41,388,341 - 41,456,261 (-)	Ensembl

RefSeq Acc Id:

NM_001191792 ⟹ NP_001178721

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	41,388,599 - 41,531,954 (-)	NCBI
Rnor_6.0	8	45,227,232 - 45,375,134 (-)	NCBI
Rnor_5.0	8	43,702,541 - 43,853,864 (-)	NCBI
Celera	8	40,986,547 - 41,129,756 (-)	NCBI

Sequence:

show sequence

GCTGAGCGGTCACTCGGCATCGCGACCCCAGCCCTAGGCATGGCCGCGCGCGAGGAGCTGTACA
GCAAAGTCACCCCGCGTAGGGACCGCCTGCAGCGTCCGGGCACCGTCAGGCATGGGTCGGCGCT
GGACCTGCTCCTGTCCATGGGCTTCCCCCGCGCCCGCGCACAAAAAGCTCTGGCATCCACGGGA
GGAAGAAGCGTTCAAGCAGCATGTGACTGGTTGTTCTCCCACGTCGGGGACCCCTTCCTGGATG
ACCCCCTGCCTCGGGAGTATGTTCTCTACCTCCGCCCAACCGGTCCATTAGCCCAGAAGCTCTC
TGACTTCTGGCAGCAGTCCAAGCAGATCTGTGGGAAGAACAAGGCCCACAACATCTTCCCCCAC
ATCACCCTCTGCCAGTTCTTCATGTGCGAGGACAGCAAGGTGGATGCTCTGGGAGAAGCCCTGC
AGACTACTGTCAGTCGATGGAGGTGTAAGTTCTCAGCCCCACTACCCCTGGAGCTGTACACCTC
CTCCAACTTCATCGGGCTCTTTGTGAAGGAAGACAGCGCAGAGGTCCTCAAGAAGTTCGCGGCT
GACTTCGCCGCAGAGGCTGCATCCAAAACCGAAGTGCACGTGGAGCCTCATAAGAAGCAGCTGC
ACGTGACACTGGCCTACCACTTCCAAGCCAGCCACCTACCCACCCTAGAGAAACTCGCCCAGAA
CATCGATGTCAAGCTAGGGTGTGACTGGGTGGCCACCATATTCTCTCGGGATATCCGATTTGCT
AATCATGAGACGTTACAGGTGATCTACCCCTATTCACCTCAGAATGATGACGAATTGGAGTTGG
TCCCAGGGGACTTCATCTTCATGTCTCCTATGGAACAGACCAGCACCAGTGAGGGCTGGATTTA
TGGCACCTCGCTGACCACTGGCTGCTCTGGGCTGCTCCCCGAGAACTACATTACCAAGGCTGAT
GAGTGTAGCACCTGGATCTTCCATGGTTCCTGTTCTATCTTGAATACGGTATCATCCAGCGCAC
TCGCATTTGGCGATGGGGCGTTAGAGAGGCGGCAGTATGAGGATCAAGGACTTGGGGAGACTAC
ACCCCTCACTATCATTTGTCAGCCCATGCAGCCCCTGAGAGTCAACAGCCAGCCTGGGCCCCAG
AAGCGATGCCTCTTTGTCTGTCGGCACGGGGAGAGGATGGACGTTGTGTTTGGGAAGTACTGGC
TATCCCAATGTTTCGATGCCAAAGGCCGCTACATACGCACCAACCTGAACATGCCTCACAGCTT
ACCTCAGCGGAGCGGCAGTTTCCGGGATTACGAGAAAGATGCTCCAATCACTGTGTTTGGGTGT
ATGCAAGCAAGACTAGTGGGTGAAGCCTTGTTAGAAAGTAACACCGTCATTGACCACGTTTATT
GCTCACCATCCCTACGCTGCGTTCAGACCGCACATAATATATTGAAAGGTTTACAACAAGACAA
TCACTTGAAGATTCGGGTCGAGCCAGGCCTATTTGAATGGACAAAGTGGGTTGCTGGGAGCACA
TTGCCAGCATGGATGCCTCCATCAGAGCTAGCAGCAGCCAACCTGAGTGTTGATACAACCTACA
GACCTCACATTCCAGTCAGCAAATTGGTGATTTCGGAATCCTATGACACCTACATCAATAGGAG
TTTCCAGGTGACGAAGGAGATAATAAGTGAATGCAAAAGTAAGGGAAATAACATTCTGATTGTG
GCCCACGCATCTTCCCTCGAAGCATGTACCTGCCAGCTCCAAGGCCTATCCCCGCAGAACTCTA
AGGACTTCGTGCAAATGGTCCGGAAGATCCCATATTTAGGCTTCTGTTCCTGCGAAGAACTGGG
AGAAACCGGAATATGGCAACTGACAGACCCACCCATCCTTCCCCTTACCCACGGACCCACTGGG
GGCTTCAACTGGAGAGAGACCCTTCTGCAAGAATAAGCTGCCTGAGGGATGGGAGGAACTTGCA
GACGAGCCCTCAGGATGTTCCTTAGCAGTGGGAAAGAAAGCCCACGCTGCATTCAAAGCAGACA
GCTCAGAATCATTTAGCATATTTCTTTTCATGCTTAGGGGACAGCGAGATTATGTCAACGAGGG
GAAGTCGTGATTCAGAGGGAGAATTTTTAAAAAATCCTTCTCTCTGGACTTGCCTAGCTAACAA
GGCTTTGGAGAATTGTCTTCCTGAGCTGAGTACCTGCTGCTGCAGAAACTACCACCCTCCTTCA
GGCTACGCATGGCTAAAGAGCCTCATTCTTCTCCCAGAGAGCTGCTCCCACCCTCAAAAGGCAT
GCAAGGGGAACGACTGTGTCTGGAATCCAACTGGGCATGGGATAGCCTTTTGTGCTCTATTTGC
AAGTTAGGCAAAGCCACCCTGAGGAGTGCATTGGTGGTTGTTAGGAACCATACATAAGAACAGT
CCTGTGTCAGACAGCAGATTCTCCTCTCGGCAGACTCCATTCATTAGCGTGCCAGGCACCCACT
TGAGGACTCCCAGCATTCACCCTGGTACCACCACTTGATCTCCAGAGCAGCCTGGCCCTTTGTG
CCTCTCTATCTGTGAAATGTGGAGA

hide sequence

RefSeq Acc Id:

XM_006242848 ⟹ XP_006242910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	41,385,419 - 41,532,248 (-)	NCBI
Rnor_6.0	8	45,224,053 - 45,375,450 (-)	NCBI
Rnor_5.0	8	43,702,541 - 43,853,864 (-)	NCBI

Sequence:

show sequence

GCCCGGCACAGGCGAGGCAGGGCCTGCCCACAAGGCTGCTTTTCCTTTTTGATCCATTCAAAAA
TTACTCATTGCAAATTCCCGGACAGCTCAGGGAGGAGAAGCTGGGGGGGGCGGAGGACAGAGAA
AGCTGCAGCAGCGCAACGCTGGGACTCCTGGACCCCGCGGGCTGAGGTCGGACCTGCAGCAGCC
ACCGGCCCGCGCCGAGCTCCAGTAGCCTCTCCAGGAAGCGTCAGTCTCAGCTCGGAGATCTGGG
AGCGCCGCCCCCGCCGTCCTCCCGGGACCCCCGGCTCTGGCGCGCGGGCGATGGGCGGCCGCTG
AGCGGTCACTCGGCATCGCGACCCCAGCCCTAGGCATGGCCGCGCGCGAGGAGCTGTACAGCAA
AGTCACCCCGCGTAGGGACCGCCTGCAGCGTCCGGGCACCGTCAGGCATGGGTCGGCGCTGGAC
CTGCTCCTGTCCATGGGCTTCCCCCGCGCCCGCGCACAAAAAGCTCTGGCATCCACGGGAGGAA
GAAGCGTTCAAGCAGCATGTGACTGGTTGTTCTCCCACGTCGGGGACCCCTTCCTGGATGACCC
CCTGCCTCGGGAGTATGTTCTCTACCTCCGCCCAACCGGTCCATTAGCCCAGAAGCTCTCTGAC
TTCTGGCAGCAGTCCAAGCAGATCTGTGGGAAGAACAAGGCCCACAACATCTTCCCCCACATCA
CCCTCTGCCAGTTCTTCATGTGCGAGGACAGCAAGGTGGATGCTCTGGGAGAAGCCCTGCAGAC
TACTGTCAGTCGATGGAGGTGTAAGTTCTCAGCCCCACTACCCCTGGAGCTGTACACCTCCTCC
AACTTCATCGGGCTCTTTGTGAAGGAAGACAGCGCAGAGGTCCTCAAGAAGTTCGCGGCTGACT
TCGCCGCAGAGGCTGCATCCAAAACCGAAGTGCACGTGGAGCCTCATAAGAAGCAGCTGCACGT
GACACTGGCCTACCACTTCCAAGCCAGCCACCTACCCACCCTAGAGAAACTCGCCCAGAACATC
GATGTCAAGCTAGGGTGTGACTGGGTGGCCACCATATTCTCTCGGGATATCCGATTTGCTAATC
ATGAGACGTTACAGGTGATCTACCCCTATTCACCTCAGAATGATGACGAATTGGAGTTGGTCCC
AGGGGACTTCATCTTCATGTCTCCTATGGAACAGACCAGCACCAGTGAGGGCTGGATTTATGGC
ACCTCGCTGACCACTGGCTGCTCTGGGCTGCTCCCCGAGAACTACATTACCAAGGCTGATGAGT
GTAGCACCTGGATCTTCCATGGTTCCTGTTCTATCTTGAATACGGTATCATCCAGCGCACTCGC
ATTTGGCGATGGGGCGTTAGAGAGGCGGCAGTATGAGGATCAAGGACTTGGGGAGACTACACCC
CTCACTATCATTTGTCAGCCCATGCAGCCCCTGAGAGTCAACAGCCAGCCTGGGCCCCAGAAGC
GATGCCTCTTTGTCTGTCGGCACGGGGAGAGGATGGACGTTGTGTTTGGGAAGTACTGGCTATC
CCAATGTTTCGATGCCAAAGGCCGCTACATACGCACCAACCTGAACATGCCTCACAGCTTACCT
CAGCGGAGCGGCAGTTTCCGGGATTACGAGAAAGATGCTCCAATCACTGTGTTTGGGTGTATGC
AAGCAAGACTAGTGGGTGAAGCCTTGTTAGAAAGTAACACCGTCATTGACCACGTTTATTGCTC
ACCATCCCTACGCTGCGTTCAGACCGCACATAATATATTGAAAGGTTTACAACAAGACAATCAC
TTGAAGATTCGGGTCGAGCCAGGCCTATTTGAATGGACAAAGTGGGTTGCTGGGAGCACATTGC
CAGCATGGATGCCTCCATCAGAGCTAGCAGCAGCCAACCTGAGTGTTGATACAACCTACAGACC
TCACATTCCAGTCAGCAAATTGGTGATTTCGGAATCCTATGACACCTACATCAATAGGAGTTTC
CAGGTGACGAAGGAGATAATAAGTGAATGCAAAAGAAATAACATTCTGATTGTGGCCCACGCAT
CTTCCCTCGAAGCATGTACCTGCCAGCTCCAAGGCCTATCCCCGCAGAACTCTAAGGACTTCGT
GCAAATGGTCCGGAAGATCCCATATTTAGGCTTCTGTTCCTGCGAAGAACTGGGAGAAACCGGA
ATATGGCAACTGACAGACCCACCCATCCTTCCCCTTACCCACGGACCCACTGGGGGCTTCAACT
GGAGAGAGACCCTTCTGCAAGAATAAGCTGCCTGAGGGATGGGAGGAACTTGCAGACGAGCCCT
CAGGATGTTCCTTAGCAGTGGGAAAGAAAGCCCACGCTGCATTCAAAGCAGACAGCTCAGAATC
ATTTAGCATATTTCTTTTCATGCTTAGGGGACAGCGAGATTATGTCAACGAGGGGAAGTCGTGA
TTCAGAGGGAGAATTTTTAAAAAATCCTTCTCTCTGGACTTGCCTAGCTAACAAGGCTTTGGAG
AATTGTCTTCCTGAGCTGAGTACCTGCTGCTGCAGAAACTACCACCCTCCTTCAGGCTACGCAT
GGCTAAAGAGCCTCATTCTTCTCCCAGAGAGCTGCTCCCACCCTCAAAAGGCATGCAAGGGGAA
CGACTGTGTCTGGAATCCAACTGGGCATGGGATAGCCTTTTGTGCTCTATTTGCAAGTTAGGCA
AAGCCACCCTGAGGAGTGCATTGGTGGTTGTTAGGAACCATACATAAGAACAGTCCTGTGTCAG
ACAGCAGATTCTCCTCTCGGCAGACTCCATTCATTAGCGTGCCAGGCACCCACTTGAGGACTCC
CAGCATTCACCCTGGTACCACCACTTGATCTCCAGAGCAGCCTGGCCCTTTGTGCCTCTCTATC
TGTGAAATGTGGAGAACAGCATGTTTGCTCTCCCAAGCACTTTGACATAACTCAGGAGGAATCA
AGAAATGGGTGGTGTATTAAATGGGGGGGTGCAGTGACATAGAATATTCATCAAATTGAAATTA
CTCCCGTGACGGCCGGATGAACTGTGAAGTCCCCACGCCTGTCTGAATCAGGGCGTGCCTTTCC
ACCCAGGCTCTAGACTGTGTTAAGCAGTTAAGGAGATTGACCTTTGGAAGGATGTAGGTTCGAT
TCACTATTTGGATCAGCAAAAAACAAAAACAAAAACAAACAAACAAACAAAAAATTCCAGTGCG
ATACAGATATTTTTAGAAACTGTACTGAGGGTCGTGTTGTTGGTCACATAGAGTCCATGTGCAG
TGTAGCAGAATGTCCGTAGGTTAGCCAGTTTTAGGGTGTCTAGGAAGCCCAGGGACTAATGTGA
ATGGTGACAGTCACAGCTGCACTGCTTCTTTTGCTGCCCTCTTCGCTTTTCTATGGTAATTTAA
AATAATGGGAGGGAGGGCCACTTGAAGGAAGCTGGAGAGTGACAGCCTTTCTGCGGGGGCTCTC
ACCACACCTACTTCCCGTATTTAGGGAGAGTGCGTGTATTTAAAGGAAGAATAAATGACAATCA
AACCAAAACATTCCATGTCGATGTCTGTTGAATTGTGTATTCCGATAGCCATGAGGGCCACATA
CAGTAGCCCGGTATGAGATAGTTAATTGTATAGCGTGTATGCAGAAATTGAAACCCCAGCCACT
GAGAGGGAACACCGATATAAAACAAATATGTCCTAGAGCATTACATTGTAACAGCCAGACATAC
ACCTATGCCTGTATACGCCTGTATGTCTTAGTCTTAAGTGTTCAGGTAACTGTATCACTTTGAT
TGGGCCACATTCCATTGTCCTTAATCCAACAGAGACAGCGTCTGACTACAGAGCCGGAGAGGAC
AGAATCTGAAGTAACTTTCTGAAGAACTTAAGTGGAAAACCCTTGAGCACAGAAACGTTTAATT
CTCCAAATTGCTTGTCAAAATGGCTGGGTGATGTGAATTCAATTAACATCTTATTGCACGCTGG
TCTGTTTAAAAGAATTCAAGATTGGGTCCAGCTGAGCAATCTTGGGAATCACACTGAATCTGTG
TGTAGAGACAACTGGATCATCAGATTTCATATGCATACAGAAGTTCTACGCTGGCAGTAGACCC
TGAGTTGAGGCTAGCTCTTTTCTATCTGCAGCTCATGCTAGCTCAGATGATACTTGGGAGAAGG
AATGAGTTAGGGACAGATCAGGGGAAAAAATTAAATTTTTTTTCACTATGTGCCTCCCCCGACC
CCCCCCCCTTTTTTTTGGTAAGTGTTGGAAAGCCATCTGAAATACTTCAGGGGAGATGACATTA
GTGGAAGGGATGACAAGTCCAAATAGTGTCCCGCTTCACCAAGTGTCCATGCTCCAGTGTTATT
CCCTGTGATTGCTGTGTGTATGTCTGACTGGAATAACTGGTGCATGCTAATACACACCATGAGG
CTGTCTTTCTCAGGCTCTTTCTTCTCACTGCTGCTTGGCCTTGAGGAGCCCTTAGCTTCACCCC
AGGGGGTGCCAGTGACATTCAGATGACAGTGTCTCTTTCCCTATGCATTCAGATTCCTGCAATC
TGAATGGCTCATTAAGGGGCCATCTGATAGCTGAAAGAGGGGGTTATTTCTCACCCTGTAATGA
AAGACTTGGGAGACTTTCTACTTTCTTATTTTAATTATACTTTAACCAAAGAGTTGTTTTCAAG
TAACCATATATTTGAAAGATGACTTTGCAAATAAATAAAAATAAAAATGGGAAGTAGCCTTCTG
GAGCCATGTGGGTTTGGTAAATCGCTGATGGTCATTTTCTTGCCAGTTCTGTTTGGAATACATA
GAGATGCTCTTCCTGCTGTGTGTAACGCTGCCCGGGATGTATCCTTTCCACTCTATGGAGTGTG
TCCCTGTGAAAACGAACTCTTATTTCAATTATCGGATGTCGTTGGGGAACTCTAATGGCAACAG
GAAGAGAAGTTCCTATCTCACTGGCTTTGTAGAAACCTTGGTTTCTGCGCCAGGAACAGAATTC
CTCTGTAACCCAGGCGCTGGCTTTAATTTCAGAGCGGCGATGAATTGCTCTTTTGAAAATACTC
TCAGTATATTCATGTGTTAGAATACAGATGAGCCTCCCACTAAGCTTCACAGGCATCGGCACAG
TCAACTGAACCAAATCTGCAGAAAGTTGGATAATGAGACTCCTGGACATTTGCATTTAAATTGA
CTGATCCAGCACATGCACCGGAGGAGGAAAAAAAGGGGGGTGTAGGGGTGTAGTCTGATGGGCC
TGAGCTCTCCAAGGAAGAAGACTGTCAAGGAGAGCAGGGGACAACCTGACTTGTCATCTATTTA
GGGGGTGTCCGTGTTACAAAGGTGATAGGGGTGGGGCTGTTAGGTGCTTTTCATCGTTAAACAT
GACTAAAATTGAATTTGCTTTTGTAACTCTTCGTCATTGATTGCTAGGAGAGTGACGGTAGGCA
TTGCCTCTCAATGCAAAAGAAATAGCTGGACTGTTACGCACATATAGTATTAGGTTTGCTGTGT
GTAGGTTGAAGATTTAGAGTCGTTAGTAGCCAGACAATATACAGTCAGTCCTCACAGATATTTG
CCTGCTCCTCCCTAGCCATTCTACATGCACAGACATTTTGCAGCTGTTAAACTATTCGTGGAAC
TCTGTATGTGATACATGCGTTAAAATGGAAACAATGTATACCCGTGCTTTGGTTGCCACTGAGA
TGGAAACAACATCCCAGAGCCTTCCAGTTTTACATAGACCACACTGAACCTGCTGTGTTAGGAA
GGCATGTCAGTTCTTTTTCTCACACGTGAGACTTTTGTATCTCATTTTTCTATATGATTTGGGT
GTATTTATTTGGGGGAAAATGTTTGTAATTATAAGACTAGAAAACCACACCTCGCTGTATGGCC
AAGTTCCTTGTACACTCCCCACGGCGTCCGTGCTTCTGTGGCTGAGAAGCTGATCCTCTGGATA
GAGCTATGGCAGCCTTGTGATCAGTTCATTGTGTCCCAGGACCATATCCACTGACATGGTTCAT
AGATGACTTAATAAAAGGAAACTGTGTCCTCAGTTGACCCAGCACAACTACAGATTAA

hide sequence

RefSeq Acc Id:

XM_039081414 ⟹ XP_038937342

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	41,385,419 - 41,532,248 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178721	(Get FASTA)	NCBI Sequence Viewer
	XP_006242910	(Get FASTA)	NCBI Sequence Viewer
	XP_038937342	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL95238	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001178721 ⟸ NM_001191792

- UniProtKB:

F1LV21 (UniProtKB/TrEMBL), A0A8I5YC04 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAREELYSKVTPRRDRLQRPGTVRHGSALDLLLSMGFPRARAQKALASTGGRSVQAACDWLFS
HVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSK
VDALGEALQTTVSRWRCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAASKTEVH
VEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSP
QNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSCSI
LNTVSSSALAFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERM
DVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGSFRDYEKDAPITVFGCMQARLVGEALLES
NTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWMPPSELAAA
NLSVDTTYRPHIPVSKLVISESYDTYINRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQL
QGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE

hide sequence

RefSeq Acc Id:	XP_006242910 ⟸ XM_006242848
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5YC04 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAREELYSKVTPRRDRLQRPGTVRHGSALDLLLSMGFPRARAQKALASTGGRSVQAACDWLFS HVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSK VDALGEALQTTVSRWRCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAASKTEVH VEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYSP QNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSCSI LNTVSSSALAFGDGALERRQYEDQGLGETTPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERM DVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGSFRDYEKDAPITVFGCMQARLVGEALLES NTVIDHVYCSPSLRCVQTAHNILKGLQQDNHLKIRVEPGLFEWTKWVAGSTLPAWMPPSELAAA NLSVDTTYRPHIPVSKLVISESYDTYINRSFQVTKEIISECKRNNILIVAHASSLEACTCQLQG LSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE hide sequence

RefSeq Acc Id:

ENSRNOP00000010873 ⟸ ENSRNOT00000010873

RefSeq Acc Id:	XP_038937342 ⟸ XM_039081414
- Peptide Label:	isoform X2
- UniProtKB:	F1LV21 (UniProtKB/TrEMBL), A0A8I5YC04 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000076960 ⟸ ENSRNOT00000102848

Protein Domains

SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LV21-F1-model_v2	AlphaFold	F1LV21	1-638	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310357	AgrOrtholog
BioCyc Gene	G2FUF-30824	BioCyc
Ensembl Genes	ENSRNOG00000008187	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000010873	ENTREZGENE
	ENSRNOP00000010873.7	UniProtKB/TrEMBL
	ENSRNOP00000076960	ENTREZGENE
	ENSRNOP00000076960.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010873	ENTREZGENE
	ENSRNOT00000010873.8	UniProtKB/TrEMBL
	ENSRNOT00000102848	ENTREZGENE
	ENSRNOT00000102848.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1240	UniProtKB/TrEMBL
	Cyclic phosphodiesterase	UniProtKB/TrEMBL
	DNA helicase RuvA subunit, C-terminal domain	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	His_Pase_superF_clade-1	UniProtKB/TrEMBL
	His_PPase_superfam	UniProtKB/TrEMBL
	SH3-like_dom	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
	UBA-like	UniProtKB/TrEMBL
	UBASH3B_SH3	UniProtKB/TrEMBL
KEGG Report	rno:315579	UniProtKB/TrEMBL
NCBI Gene	315579	ENTREZGENE
PANTHER	UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED	UniProtKB/TrEMBL
	UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN B	UniProtKB/TrEMBL
Pfam	His_Phos_1	UniProtKB/TrEMBL
	SH3_9	UniProtKB/TrEMBL
PhenoGen	Ubash3b	PhenoGen
PROSITE	SH3	UniProtKB/TrEMBL
SMART	SH3	UniProtKB/TrEMBL
Superfamily-SCOP	SH3	UniProtKB/TrEMBL
	SSF53254	UniProtKB/TrEMBL
	UBA_like	UniProtKB/TrEMBL
UniProt	A0A8I5YC04	ENTREZGENE, UniProtKB/TrEMBL
	F1LV21	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-05-15	Ubash3b	ubiquitin associated and SH3 domain containing, B	Sts-1	Cbl-interacting protein Sts-1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-11	Sts-1	Cbl-interacting protein Sts-1	Ubash3b	ubiquitin associated and SH3 domain containing, B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Ubash3b	ubiquitin associated and SH3 domain containing, B	RGD1310357_predicted	similar to RIKEN cDNA 2810457I06 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1310357_predicted	similar to RIKEN cDNA 2810457I06 (predicted)	LOC315579_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC315579_predicted	similar to RIKEN cDNA 2810457I06 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar