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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of calcidiol 1-monooxygenase activity
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Accession:GO:0010956 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.



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negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA
(PMID:16549446)
GO_REF:0000107
RGD
Ensembl
PMID:16549446 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) RGD PMID:15243130 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    metabolic process 12191
      negative regulation of metabolic process 3323
        negative regulation of hormone metabolic process 14
          negative regulation of hormone biosynthetic process 12
            negative regulation of calcidiol 1-monooxygenase activity 3
Path 2
Term Annotations click to browse term
  biological_process 19874
    biological regulation 13526
      regulation of biological process 13079
        regulation of metabolic process 6909
          regulation of primary metabolic process 5904
            regulation of lipid metabolic process 391
              regulation of steroid metabolic process 113
                negative regulation of steroid metabolic process 29
                  negative regulation of steroid biosynthetic process 28
                    negative regulation of vitamin D biosynthetic process 5
                      negative regulation of calcidiol 1-monooxygenase activity 3
paths to the root