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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of molecular function
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Accession:GO:0065009 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
Synonyms:exact_synonym: regulation of a molecular function



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activation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrhr growth hormone releasing hormone receptor IDA RGD PMID:9845677 RGD:1601338 NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:8440169 RGD:2292602 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 IDA RGD PMID:8224221 RGD:70054 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597
JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pawr pro-apoptotic WT1 regulator IMP RGD PMID:10349840 RGD:9835366 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp4 caspase 4 TAS RGD PMID:11684090 RGD:632459 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Tnfsf15 TNF superfamily member 15 IDA RGD PMID:11911831 RGD:634236 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad3 SMAD family member 3 IMP TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
activation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5 eukaryotic translation initiation factor 5 IDA RGD PMID:10805737 RGD:10755758 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15158121 RGD:1642626 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Rasa1 RAS p21 protein activator 1 IDA RGD PMID:8226805 RGD:9999452 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IMP RGD PMID:1379346 RGD:10003125 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:18930714 RGD:10043296 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:11818507 RGD:633057 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
activation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1r1 ADCYAP receptor type I IDA RGD PMID:8396727 RGD:631732 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
JBrowse link
G Adra1a adrenoceptor alpha 1A IDA RGD PMID:7935320 RGD:69745 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Agt angiotensinogen IMP RGD PMID:11100981 RGD:1582152 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein IDA RGD PMID:7835339 RGD:68218 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
JBrowse link
G Gnaq G protein subunit alpha q IMP RGD PMID:14981460 RGD:1598489 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IDA RGD PMID:11388899 RGD:1599963 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
JBrowse link
activation of phospholipase D activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gna13 G protein subunit alpha 13 IMP RGD PMID:12435801 RGD:1598460 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
JBrowse link
G Hpca hippocalcin IDA RGD PMID:11211872 RGD:9686445 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate IDA RGD PMID:16341931 RGD:9685306 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Prkcz protein kinase C, zeta IMP RGD PMID:16113073 RGD:1642674 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:16054095 RGD:2311420 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 IDA RGD PMID:16054095 RGD:2311420 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12086672 RGD:1580677 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:20841353 RGD:150540305 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcz protein kinase C, zeta IMP in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
activation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stim1 stromal interaction molecule 1 IMP RGD PMID:21541286 RGD:7175076 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Stim2 stromal interaction molecule 2 IMP RGD PMID:21541286 RGD:7175076 NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
JBrowse link
cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha IMP RGD PMID:9918814 PMID:16580131 PMID:9343439 PMID:10620707 RGD:2298880, RGD:2298917, RGD:2298908, RGD:2298882 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta IMP RGD PMID:9343439 PMID:16580131 RGD:2298908, RGD:2298917 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
cytoplasmic sequestering of transcription factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 IMP RGD PMID:11439354 RGD:727319 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:20705669 RGD:5509896 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
negative regulation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 IDA RGD PMID:20410303 RGD:7242424 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP RGD PMID:19574217 RGD:6902943 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Akap9 A-kinase anchoring protein 9 IMP RGD PMID:18772391 RGD:2313147 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IMP RGD PMID:15147298 RGD:2315493 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:10869375 RGD:632981 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:8702617 RGD:1601497 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
negative regulation of alkaline phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
negative regulation of AMPA receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grip1 glutamate receptor interacting protein 1 IMP RGD PMID:12597860 RGD:152995391 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273
JBrowse link
negative regulation of anion channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk6 G protein-coupled receptor kinase 6 IMP Cl-/HCO3- exchange activity RGD PMID:17170521 RGD:5684927 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644
JBrowse link
negative regulation of ATP-dependent activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnn3 calponin 3 IDA microtubule-activated ncd 335 ATPase RGD PMID:12564930 RGD:727577 NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
JBrowse link
negative regulation of calcium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:15728831 RGD:8554004 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
negative regulation of calcium-dependent ATPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IMP RGD PMID:10861851 RGD:9590176 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of catalytic activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl4 angiopoietin-like 4 TAS RGD PMID:15863837 RGD:1578348 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Cast calpastatin IDA RGD PMID:17429681 RGD:1626249 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R IMP arylalkylamine N-acetyltransferase activity RGD PMID:15798208 RGD:9854643 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867
JBrowse link
G Renbp renin binding protein IDA RGD PMID:11726282 RGD:5132613 NCBI chr  X:151,661,463...151,670,538
Ensembl chr  X:151,661,458...151,670,516
JBrowse link
negative regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 IDA RGD PMID:20624795 RGD:6849299 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Fgf12 fibroblast growth factor 12 IDA RGD PMID:12401812 RGD:6484231 NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607
JBrowse link
negative regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 IDA RGD PMID:15829559 RGD:1599733 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
negative regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aip aryl-hydrocarbon receptor-interacting protein IDA RGD PMID:12810716 RGD:632260 NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IDA RGD PMID:22975349 RGD:8554232 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Rgn regucalcin IDA RGD PMID:1656206 RGD:9590243 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IDA RGD PMID:10721722 RGD:632478 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IDA RGD PMID:10721722 RGD:632478 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:22584582 RGD:10045364 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:23690069 RGD:13792722 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Htt huntingtin IMP RGD PMID:17124493 RGD:6902918 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA RGD PMID:15211592 RGD:1625666 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IMP caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Ep300 E1A binding protein p300 IMP cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Gpi glucose-6-phosphate isomerase IMP RGD PMID:12615053 RGD:1600634 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 IMP RGD PMID:15102845 RGD:1304324 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:21874357 RGD:150540304 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IDA reduced cleavage of Casp8 and Casp9 in brain following hypoxic/ischemic injury RGD PMID:16397188 RGD:1626654 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Il6 interleukin 6 IDA RGD PMID:19061939 RGD:2306937 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Por cytochrome p450 oxidoreductase IMP caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ptma prothymosin alpha IDA RGD PMID:12522243 RGD:734494 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
JBrowse link
negative regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 IDA
IMP
RGD PMID:8183366 PMID:8799886 RGD:61642, RGD:9743956 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Mtnr1b melatonin receptor 1B IDA RGD PMID:14962062 RGD:9588668 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
JBrowse link
negative regulation of DNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac2 histone deacetylase 2 IMP RGD PMID:21383775 RGD:9590238 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IMP Rela RGD PMID:17473852 RGD:5688754 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Id1 inhibitor of DNA binding 1 IMP RGD PMID:7623812 RGD:9686118 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Sirt1 sirtuin 1 IMP Rela RGD PMID:22044919 RGD:10047123 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
negative regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln1 egl-9 family hypoxia-inducible factor 1 IDA RGD PMID:20308610 RGD:6483365 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IDA STAT5b RGD PMID:16584384 RGD:1625011 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor IDA RGD PMID:11641275 RGD:1599577 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 IMP RGD PMID:12697699 RGD:1624302 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Rpl11 ribosomal protein L11 IDA RGD PMID:16280383 RGD:11035228 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Thra thyroid hormone receptor alpha IDA RGD PMID:2537467 RGD:1580107 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thra_v2 thyroid hormone receptor alpha, variant 2 IDA RGD PMID:2537467 RGD:1580107
negative regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IDA RGD PMID:19240864 RGD:7411612 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Renbp renin binding protein IDA RGD PMID:11926999 RGD:727355 NCBI chr  X:151,661,463...151,670,538
Ensembl chr  X:151,661,458...151,670,516
JBrowse link
G Serpine1 serpin family E member 1 IDA RGD PMID:10717410 RGD:8547889 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
negative regulation of GTP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rap1gap Rap1 GTPase-activating protein IMP RGD PMID:19066305 RGD:9835342 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253
JBrowse link
negative regulation of GTP cyclohydrolase I activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gchfr GTP cyclohydrolase I feedback regulator IDA RGD PMID:8702680 RGD:728623 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
negative regulation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:15870074 RGD:2325307 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Arrb1 arrestin, beta 1 IDA RGD PMID:1517224 RGD:631708 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arrb2 arrestin, beta 2 IDA RGD PMID:1517224 RGD:631708 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 IDA RGD PMID:16413169 RGD:1625628 NCBI chr 6:137,439,572...138,191,575
Ensembl chr 6:137,439,540...138,191,575
JBrowse link
G Rgn regucalcin IMP RGD PMID:11510494 RGD:9590205 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Tsc1 TSC complex subunit 1 IMP RGD PMID:15611338 RGD:1601406 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
negative regulation of hexokinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gckr glucokinase regulator IDA RGD PMID:14627435 RGD:1598592 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
negative regulation of hydrolase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcz protein kinase C, zeta IDA inhibition of acid sphingomyelinase translocation to cell surface and activation RGD PMID:17346242 RGD:1642658 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
negative regulation of inward rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx27 sorting nexin 27 IDA RGD PMID:21422294 RGD:8554349 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906
JBrowse link
negative regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IMP RGD PMID:12064607 RGD:1299562 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
negative regulation of kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase IDA RGD PMID:10411542 RGD:5134371 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:19762078 RGD:150429972 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 IDA RGD PMID:9366267 RGD:5134981 NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 IDA due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
negative regulation of leucine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IDA RGD PMID:2280766 RGD:9590217 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of lipase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 IDA RGD PMID:10419291 RGD:1626385 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Por cytochrome p450 oxidoreductase IDA phospholipase D RGD PMID:18801337 RGD:4889814 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
negative regulation of lipoprotein lipase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl4 angiopoietin-like 4 TAS RGD PMID:14570927 RGD:1302799 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
negative regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:17182785 RGD:2301767 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Kng2 kininogen 2 IDA in ConA- or PHA-stimulated Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IDA RGD PMID:9857190 RGD:10044039 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:14612383 RGD:1580517 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mprip myosin phosphatase Rho interacting protein IMP RGD PMID:17661354 RGD:9685557 NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118
JBrowse link
negative regulation of NAD(P)H oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 IMP RGD PMID:19752235 RGD:8549634 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
negative regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IMP RGD PMID:16537391 RGD:1582129 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:18561998 RGD:2316219 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:18005341 RGD:10045554 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
negative regulation of NMDA glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase IMP RGD PMID:20698836 RGD:13463453 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
negative regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxyd2 FXYD domain-containing ion transport regulator 2 IMP RGD PMID:15280368 RGD:1598989 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyss cystatin S IDA Papain
Ficin
RGD PMID:7575236 PMID:3263967 RGD:2306757, RGD:1299643 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610
JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
negative regulation of phospholipase A2 activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IDA RGD PMID:2969352 RGD:7421659 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
negative regulation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snap91 synaptosome associated protein 91 IDA RGD PMID:11779129 RGD:70605 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367
JBrowse link
negative regulation of phospholipase D activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snap91 synaptosome associated protein 91 IDA RGD PMID:9188501 RGD:13506241 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367
JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppia peptidylprolyl isomerase A IDA RGD PMID:19832699 RGD:7247324 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IDA
IMP
RGD PMID:12016225 PMID:10585469 RGD:625568, RGD:9999389 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
JBrowse link
G Rgn regucalcin IMP RGD PMID:10922512 RGD:9590172 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of potassium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pten phosphatase and tensin homolog IMP RGD PMID:24103758 RGD:12802338 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
negative regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA beta-amyloid aggregation RGD PMID:14706557 RGD:2312790 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K IMP RGD PMID:9553145 RGD:2303817 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Id1 inhibitor of DNA binding 1 IMP RGD PMID:23831032 RGD:9686139 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:20802490 RGD:152995511 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 IDA RGD PMID:12270929 RGD:1299366 NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463
JBrowse link
G Senp2 SUMO specific peptidase 2 IDA Axin1 to Dvl1 RGD PMID:10944533 RGD:1299408 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
JBrowse link
negative regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a RGD PMID:12590138 RGD:1625697 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:17289031 RGD:9587773 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Drd1 dopamine receptor D1 IMP RGD PMID:12688394 RGD:1581394 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd5 dopamine receptor D5 IMP RGD PMID:12688394 RGD:1581394 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IMP RGD PMID:21668448 RGD:10401931 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Il6 interleukin 6 IDA Phospholamban phosphorylation RGD PMID:15845578 RGD:2306941 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilk integrin-linked kinase IMP GSK-3 activity as a Tau protein kinase RGD PMID:12629168 RGD:2302091 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Pcp4 Purkinje cell protein 4 IDA RGD PMID:10751438 RGD:1579763 NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha TAS RGD PMID:1491692 RGD:729428 NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282
JBrowse link
G Rgn regucalcin IMP RGD PMID:11455566 RGD:9590207 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11500506 RGD:13508599 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
negative regulation of receptor binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP angiotensin receptor RGD PMID:24262995 RGD:39939015 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
negative regulation of selenocysteine insertion sequence binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4a3 eukaryotic translation initiation factor 4A3 IDA RGD PMID:19716792 RGD:10045552 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpina1 serpin family A member 1 IDA RGD PMID:19240864 RGD:7411612 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IDA RGD PMID:12771515 RGD:724699 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
negative regulation of signaling receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP extrasynaptic NMDAR RGD PMID:22593067 RGD:6484258 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Pten phosphatase and tensin homolog IMP GABA A receptors RGD PMID:24044036 RGD:12802358 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
negative regulation of sodium:proton antiporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd3 dopamine receptor D3 IMP RGD PMID:15265811 RGD:1625070 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:16556873 RGD:1580657 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
negative regulation of transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insr insulin receptor IMP P-glycoprotein RGD PMID:19049803 RGD:2307019 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17960496 RGD:7207144 NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein IMP RGD PMID:24751537 RGD:10047103 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IMP RGD PMID:26584289 RGD:155804278 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:15937148 RGD:9835002 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
negative regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 PMID:21943416 PMID:21943417 RGD:7243967, RGD:7242916, RGD:12910700 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:19219384 PMID:21943416 PMID:14679187 RGD:7243947, RGD:7242916, RGD:7243967 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
positive regulation of actin filament binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Poldip2 DNA polymerase delta interacting protein 2 IMP RGD PMID:30354218 RGD:124713558 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605
JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:21143600 RGD:8693686 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Akap5 A-kinase anchoring protein 5 IDA RGD PMID:20410303 RGD:7242424 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Gcg glucagon ISO RGD PMID:2235678 RGD:11556254 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IMP RGD PMID:15901773 RGD:1598578 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
positive regulation of alkaline phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin subunit alpha 2 IMP RGD PMID:10867645 RGD:2307406 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Smad3 SMAD family member 3 IDA rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
positive regulation of AMPA receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 IDA RGD PMID:16093395 RGD:13515081 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 IDA RGD PMID:12771129 RGD:13515082 NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IDA RGD PMID:12771129 RGD:13515082 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 IDA RGD PMID:12771129 RGD:13515082 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089
JBrowse link
positive regulation of ATP-dependent activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:8760245 RGD:8548528 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Tpm1 tropomyosin 1 IMP RGD PMID:11329279 RGD:1600520 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Tpm1_v1 tropomyosin 1, variant 1 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v2 tropomyosin 1, variant 2 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v3 tropomyosin 1, variant 3 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v4 tropomyosin 1, variant 4 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v5 tropomyosin 1, variant 5 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v6 tropomyosin 1, variant 6 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v7 tropomyosin 1, variant 7 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v8 tropomyosin 1, variant 8 IMP RGD PMID:11329279 RGD:1600520
G Tpm1_v9 tropomyosin 1, variant 9 IMP RGD PMID:11329279 RGD:1600520
positive regulation of ATPase-coupled calcium transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IDA RGD PMID:10797571 RGD:9590178 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
positive regulation of catalytic activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IMP RGD PMID:11100981 RGD:1582152 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Cdc42 cell division cycle 42 IMP RGD PMID:18562481 RGD:5688290 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Clps colipase IDA RGD PMID:8656075 RGD:2303166 NCBI chr20:6,620,529...6,622,709
Ensembl chr20:6,620,529...6,622,689
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP Eno1 RGD PMID:21958194 RGD:10059326 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Ngb neuroglobin IMP RGD PMID:23036890 RGD:9743969 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Npm1 nucleophosmin 1 IDA DNA polymerase alpha RGD PMID:11481036 RGD:1600909 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Npm2 nucleophosmin/nucleoplasmin 2 IDA DNA polymerase alpha, lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chr15:45,722,282...45,729,336
Ensembl chr15:45,722,400...45,729,726
JBrowse link
positive regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IDA RGD PMID:22505670 RGD:6893581 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IDA RGD PMID:20806410 RGD:9686372 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IMP RGD PMID:23785408 RGD:7296920 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:19359367 RGD:9743912 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
positive regulation of chromatin binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B IMP Ep300 RGD PMID:20870727 RGD:9590266 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Kdm1a lysine demethylase 1A IMP RGD PMID:20418916 RGD:9588315 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IMP RGD PMID:25135974 RGD:9589119 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794
JBrowse link
G Mfn2 mitofusin 2 IMP Tfap2a RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
positive regulation of collagen binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin subunit alpha 2 IMP epithelial cell binding mediated by syndecan-2 RGD PMID:19394307 RGD:2307393 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
positive regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D IMP RGD PMID:16706838 RGD:6906921 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
positive regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnat1 G protein subunit alpha transducin 1 IDA RGD PMID:7878085 RGD:1599022 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc6 cell division cycle 6 IMP RGD PMID:22223646 RGD:10045360 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 IDA RGD PMID:10721722 RGD:632478 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:22223646 RGD:10045360 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15105833 RGD:2313858 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Arrb1 arrestin, beta 1 IMP RGD PMID:19171933 RGD:5510006 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Casp12 caspase 12 IMP RGD PMID:17083921 RGD:2311464 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Ccn2 cellular communication network factor 2 IMP caspase 3/7 RGD PMID:19625611 RGD:2314487 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Fas Fas cell surface death receptor IMP RGD PMID:15519734 RGD:8662904 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:14522843 RGD:2304239 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:18322138 RGD:8693423 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Pycard PYD and CARD domain containing IMP RGD PMID:19401709 RGD:5491174 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17425560 RGD:1642961 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:20193664 RGD:11553917 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor IMP RGD PMID:12131680 RGD:14995454 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:15107407 RGD:1578311 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Myo5a myosin VA IMP RGD PMID:29217155 RGD:42721980 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
JBrowse link
positive regulation of DNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:19057620 RGD:2311715 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Itga2 integrin subunit alpha 2 IMP DNA binding by NF-kappaB RGD PMID:19239475 RGD:2307394 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Jak2 Janus kinase 2 IMP Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:12873812 RGD:10059626 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP RGD PMID:11181516 RGD:2311195 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16272348 RGD:1598594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpu heterogeneous nuclear ribonucleoprotein U IDA RGD PMID:20554522 RGD:10058983 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
positive regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:19057620 RGD:2311715 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit IDA RGD PMID:12371906 RGD:629541 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Hmga2 high mobility group AT-hook 2 IMP RGD PMID:9311991 RGD:1601604 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Jak2 Janus kinase 2 IMP Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 IDA RGD PMID:11713241 RGD:727330 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16272348 RGD:1598594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I IDA glucocorticoid receptor, independent of sumoylation activity or presence of a GME RGD PMID:11812797 RGD:2301354 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 IDA RGD PMID:8123045 RGD:11535022 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
positive regulation of dUTP diphosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IDA RGD PMID:1315924 RGD:2301218 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 IMP MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IMP RGD PMID:19574994 RGD:2317913 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
positive regulation of exoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcea1 transcription elongation factor A1 IDA RGD PMID:16046193 RGD:9693728 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
Ensembl chr15:14,631,454...14,668,745
JBrowse link
positive regulation of glucokinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp12 dual specificity phosphatase 12 IDA increases glucokinase activity by direct dephosphorylation RGD PMID:10913113 RGD:68242 NCBI chr13:83,122,192...83,131,800
Ensembl chr13:83,122,193...83,131,285
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 IMP RGD PMID:15047617 RGD:2302684 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 IDA RGD PMID:16980436 RGD:2304071 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
JBrowse link
positive regulation of glutamate-cysteine ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclm glutamate cysteine ligase, modifier subunit IDA RGD PMID:16137247 RGD:1582663 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
positive regulation of GTP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rapgef3 Rap guanine nucleotide exchange factor 3 IMP Ran-GTP RGD PMID:18689492 RGD:9835375 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
positive regulation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amph amphiphysin IDA RGD PMID:9348539 RGD:631926 NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315
JBrowse link
G Bin1 bridging integrator 1 IDA RGD PMID:9348539 RGD:631926 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Gnao1 G protein subunit alpha o1 IMP RGD PMID:7544301 RGD:2302012 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IMP basal and EGF-activated Rac1 RGD PMID:17183546 RGD:2292641 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 IMP RGD PMID:18348285 RGD:2314690 NCBI chr 2:227,500,366...227,645,213
Ensembl chr 2:227,500,367...227,645,169
JBrowse link
G Rasa1 RAS p21 protein activator 1 IMP RGD PMID:14707121 RGD:9999423 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IMP RGD PMID:15798216 RGD:10003119 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
JBrowse link
G Rgn regucalcin IDA RGD PMID:11693188 RGD:9590216 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:20530129 PMID:9430692 RGD:7207369, RGD:7207375 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:14711826 RGD:1304283 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Guca1a guanylate cyclase activator 1A IDA RGD PMID:12545196 RGD:1599357 NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565
JBrowse link
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IMP RGD PMID:22187436 RGD:13514092 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
positive regulation of hydrolase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp1 fatty acid binding protein 1 IDA peroxisomal medium- and long-chain acyl-CoA thioesterases RGD PMID:16262600 RGD:1626442 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Gm2a ganglioside GM2 activator IDA Phospholipase D RGD PMID:9770472 RGD:1598995 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
JBrowse link
positive regulation of ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr3a 5-hydroxytryptamine receptor 3A IDA RGD PMID:10854267 RGD:61635 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B IDA RGD PMID:10854267 RGD:61635 NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:49,279,173...49,308,444
JBrowse link
positive regulation of isoleucine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl5 ribosomal protein L5 IMP RGD PMID:1665486 RGD:11040680 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IMP RGD PMID:20716917 RGD:10412640 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15226266 RGD:1642623 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:16203995 RGD:10043312 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
JBrowse link
positive regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:23407708 RGD:7777099 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:15087293 RGD:1624373 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Ilk integrin-linked kinase IMP inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 IMP RGD PMID:23987506 RGD:11049533 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:10969813 RGD:1600497 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:16935468 RGD:1642549 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:11941412 RGD:150523765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 IMP RGD PMID:21607062 RGD:5508182 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058
JBrowse link
positive regulation of methionine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl5 ribosomal protein L5 IMP RGD PMID:1665486 RGD:11040680 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
positive regulation of microtubule binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21229611 RGD:10403032 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
positive regulation of mRNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpl heterogeneous nuclear ribonucleoprotein L IMP RGD PMID:19273590 RGD:9999430 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553
JBrowse link
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain IMP RGD PMID:12631082 RGD:11040676 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
positive regulation of NF-kappaB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amh anti-Mullerian hormone IMP RGD PMID:11356848 RGD:70295 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19211730 RGD:5130956 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Icam1 intercellular adhesion molecule 1 IMP RGD PMID:9062344 RGD:1600239 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IMP RGD PMID:15939736 RGD:7495757 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Itgb2 integrin subunit beta 2 IMP RGD PMID:9062344 RGD:1600239 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:14576830 RGD:1600488 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Tgfb1 transforming growth factor, beta 1 IDA RGD PMID:15781474 RGD:1579751 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16651628 RGD:1598593 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 IMP RGD PMID:8982082 RGD:730027 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Traf2 Tnf receptor-associated factor 2 IMP RGD PMID:10713108 RGD:2298798 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IDA RGD PMID:20529840 RGD:7241266 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:14576830 RGD:1600488 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:22870324 RGD:9831169 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:21926342 RGD:10041069 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:9537427 RGD:14985259 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
positive regulation of NMDA glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 IMP RGD PMID:24089484 RGD:11570552 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Pink1 PTEN induced kinase 1 IMP RGD PMID:20698836 RGD:13463453 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Rgs9 regulator of G-protein signaling 9 IDA RGD PMID:16510730 RGD:1599994 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
JBrowse link
positive regulation of oxidative phosphorylation uncoupler activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a4 solute carrier family 25 member 4 IMP RGD PMID:18251717 RGD:7242053 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
positive regulation of oxidoreductase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 IMP p-nitrophenol hydroxylase, dimethylnitrosamine demethylase RGD PMID:11325963 RGD:4145669 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
positive regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnm2 dynamin 2 IMP RGD PMID:12205083 RGD:727418 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
positive regulation of phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IMP RGD PMID:9671264 RGD:9590174 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rpl5 ribosomal protein L5 IDA RGD PMID:7649987 RGD:2316860 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
positive regulation of phospholipase A2 activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta IDA RGD PMID:15576376 RGD:6482753 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
positive regulation of phospholipase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:11211872 RGD:9686445 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
positive regulation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptafr platelet-activating factor receptor IDA RGD PMID:8798508 RGD:9999203 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
positive regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak2 Janus kinase 2 IMP Ptpn11 activity RGD PMID:17021051 RGD:1641809 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Pawr pro-apoptotic WT1 regulator IMP RGD PMID:23219599 RGD:9835413 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:24265448 RGD:8693600 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
positive regulation of potassium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:23212096 RGD:7244285 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
positive regulation of potassium:proton exchanging ATPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rapgef3 Rap guanine nucleotide exchange factor 3 IMP RGD PMID:11897793 RGD:625394 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
positive regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP Npc1l1, Rab11a, Myo5b RGD PMID:21844200 RGD:5688279 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
G Cald1 caldesmon 1 IDA RGD PMID:3384851 RGD:2303065 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP Akt1-Hsp90 RGD PMID:18443201 RGD:4108490 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IDA RGD PMID:11415446 RGD:4892111 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta IDA RGD PMID:7908909 RGD:633201 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 IMP RGD PMID:9695949 RGD:633354 NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473
JBrowse link
G Plk2 polo-like kinase 2 IDA Sipa1l1 binding to Btcr and Fbxw11 RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Ramp1 receptor activity modifying protein 1 IDA RGD PMID:11556887 RGD:1299115 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
JBrowse link
G Ramp2 receptor activity modifying protein 2 IDA RGD PMID:11556887 RGD:1299115 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Trim28 tripartite motif-containing 28 IDA RGD PMID:12748187 RGD:1299608 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
positive regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 IDA RGD PMID:15228590 RGD:1304344 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Axin2 axin 2 IDA RGD PMID:9566905 RGD:68736 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:7642608 RGD:632489 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498
JBrowse link
G Ccnb1 cyclin B1 IMP histone H1 RGD PMID:15291744 RGD:1578405 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:18556591 RGD:11541067 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:21572393 RGD:9587767 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:9653190 RGD:8554053 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
JBrowse link
G Sdc4 syndecan 4 IMP RGD PMID:12571249 RGD:1580031 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Marcks myristoylated alanine rich protein kinase C substrate IDA RGD PMID:16341931 RGD:9685306 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP Akt1 RGD PMID:18443201 RGD:4108490 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
positive regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Poldip2 DNA polymerase delta interacting protein 2 IDA RGD PMID:30726115 RGD:124713559 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605
JBrowse link
positive regulation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IMP RGD PMID:20844246 RGD:8801954 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
positive regulation of superoxide dismutase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IDA RGD PMID:15375603 RGD:9590277 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
positive regulation of threonine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl5 ribosomal protein L5 IMP RGD PMID:8049265 RGD:1556518 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IDA RGD PMID:20478999 RGD:13514093 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IDA RGD PMID:12821675 RGD:737839 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G S100a1 S100 calcium binding protein A1 IDA RGD PMID:19657060 RGD:7205633 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
positive regulation of voltage-gated chloride channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 IMP RGD PMID:29344669 RGD:213230158 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
JBrowse link
G Ptafr platelet-activating factor receptor IDA RGD PMID:8168510 RGD:61717 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
positive regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:12183335 RGD:728122 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 IMP RGD PMID:22056818 RGD:14390155 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 IDA RGD PMID:21943416 RGD:7242916 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682
JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IDA RGD PMID:21943417 RGD:12910700 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IDA RGD PMID:21943417 RGD:12910700 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IMP RGD PMID:7568179 RGD:12910723 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:24097558 RGD:39939085 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Kif5b kinesin family member 5B IMP RGD PMID:24198377 RGD:11073607 NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
receptor transactivation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 IMP RGD PMID:25232008 RGD:13703036 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
regulation of acetylcholine-gated cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit IMP RGD PMID:11904236 RGD:704387 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
regulation of anion channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hk1 hexokinase 1 IDA RGD PMID:14561215 RGD:2302670 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
JBrowse link
regulation of ATP-dependent activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpm1 tropomyosin 1 IDA RGD PMID:19041430 RGD:7242195 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
regulation of catalase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja8 gap junction protein, alpha 8 IMP RGD PMID:27871290 RGD:150429989 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
JBrowse link
regulation of catalytic activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 IDA RGD PMID:8789462 PMID:10525147 RGD:2326068, RGD:727285 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 IDA RGD PMID:16648175 RGD:1600447 NCBI chr 7:129,963,105...129,980,532
Ensembl chr 7:129,963,105...129,980,561
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 IDA RGD PMID:16648175 RGD:1600447 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
regulation of cyclic nucleotide-gated ion channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:11420311 RGD:7244388 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
regulation of cytochrome-c oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha IMP RGD PMID:26722473 RGD:11341663 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:22275377 RGD:153297769 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kng2 kininogen 2 IDA RGD PMID:3356189 RGD:1600550 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
regulation of glutathione peroxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja8 gap junction protein, alpha 8 IMP RGD PMID:27871290 RGD:150429989 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
JBrowse link
regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
regulation of kainate selective glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grip1 glutamate receptor interacting protein 1 IMP RGD PMID:12597860 RGD:152995391 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273
JBrowse link
G Pick1 protein interacting with PRKCA 1 IMP RGD PMID:12597860 RGD:152995391 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
regulation of mRNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carm1 coactivator-associated arginine methyltransferase 1 IMP RGD PMID:22736542 RGD:9586719 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 IDA Secisbp2 RGD PMID:19716792 RGD:10045552 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
regulation of NMDA receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22593067 RGD:6484258 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxyd2 FXYD domain-containing ion transport regulator 2 IDA RGD PMID:11756431 RGD:625472 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
regulation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:21767260 RGD:7349319 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186
JBrowse link
regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IMP RGD PMID:12435803 RGD:633811 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 IDA RGD PMID:21712390 RGD:7245493 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399
JBrowse link
regulation of protein ADP-ribosylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA upregulation RGD PMID:16093393 RGD:1601081 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312
JBrowse link
regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ran RAN, member RAS oncogene family IDA RGD PMID:9398662 RGD:9835011 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IDA RGD PMID:12385827 RGD:1579945 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha IDA RGD PMID:11907174 PMID:16816331 RGD:2312572, RGD:2312556 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta IDA RGD PMID:11907174 PMID:16816331 RGD:2312572, RGD:2312556 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha IDA RGD PMID:11907174 PMID:16816331 RGD:2312572, RGD:2312556 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta IDA RGD PMID:11907174 PMID:16816331 RGD:2312572, RGD:2312556 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
regulation of Rho-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 IDA RGD PMID:9681506 RGD:728288 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IDA RGD PMID:15628869 RGD:7241270 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IDA RGD PMID:15628869 RGD:7241270 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IDA RGD PMID:15628869 RGD:7241270 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
regulation of signaling receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10026131 RGD:2303749 NCBI chr11:68,008,245...68,053,242 JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I IDA glucocorticoid receptor, independent of sumoylation activity or presence of a GME RGD PMID:11812797 RGD:2301354 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link
regulation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IC RGD PMID:23109337 RGD:7241220 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IC RGD PMID:23109337 RGD:7241220 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IC RGD PMID:23109337 RGD:7241220 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:12547829 RGD:6482757 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:17432954 RGD:2299884 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17224447 RGD:7207146 NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IMP RGD PMID:17196942 RGD:1598976 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 IDA RGD PMID:12042350 RGD:632406 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link

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