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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lithium chloride
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Accession:CHEBI:48607 term browser browse the term
Definition:A metal chloride salt with a Li(+) counterion.
Synonyms:related_synonym: Formula=ClLi;   InChI=1S/ClH.Li/h1H;/q;+1/p-1;   InChIKey=KWGKDLIKAYFUFQ-UHFFFAOYSA-M;   LiCl;   Lithiumchlorid;   SMILES=[Li+].[Cl-];   chlorure de lithium;   cloruro de litio;   lithii chloridum
 xref: CAS:7447-41-8
 xref_mesh: MESH:D018021
 xref: PMID:21301855;   PMID:24398558



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lithium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2ml1 alpha-2-macroglobulin-like 1 decreases expression ISO Lithium Chloride results in decreased expression of OVOS2 mRNA CTD PMID:23527032 NCBI chr 4:161,815,111...161,857,286
Ensembl chr 4:161,814,708...161,857,343
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression ISO Lithium Chloride results in decreased expression of ABAT mRNA CTD PMID:15711924 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Lithium Chloride results in increased expression of ABCB1 protein CTD PMID:18624906 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abhd11 abhydrolase domain containing 11 increases expression ISO Lithium Chloride results in increased expression of ABHD11 mRNA CTD PMID:23527032 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398
JBrowse link
G Abi2 abl-interactor 2 decreases expression ISO Lithium Chloride results in decreased expression of ABI2 mRNA CTD PMID:23527032 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Lithium Chloride results in decreased expression of ACADM mRNA; Lithium Chloride results in decreased expression of ACADM protein CTD PMID:26993217 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE protein] CTD PMID:32494933 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase multiple interactions
increases degradation
decreases stability
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein CTD PMID:22944069 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adgrb3 adhesion G protein-coupled receptor B3 increases expression ISO Lithium Chloride results in increased expression of ADGRB3 mRNA CTD PMID:15711924 NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 increases expression ISO Lithium Chloride results in increased expression of ADGRE5 mRNA CTD PMID:23527032 NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] CTD PMID:32494933 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP [Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of AGTR2 mRNA CTD PMID:32494933 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA CTD PMID:21498875 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein]
[Lithium Chloride co-treated with Pilocarpine] results in increased phosphorylation of AKT1 protein
CTD PMID:22820424 PMID:31018114 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression ISO Lithium Chloride results in decreased expression of ALDH1A3 mRNA CTD PMID:15711924 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO Lithium Chloride results in increased expression of ALOX5AP mRNA CTD PMID:23527032 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO Lithium Chloride results in increased expression of ALPG mRNA CTD PMID:23527032 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836
JBrowse link
G Alpp alkaline phosphatase, placental increases activity ISO Lithium Chloride results in increased activity of ALPP protein CTD PMID:16053526 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Amy2a3 amylase 2a3 multiple interactions EXP Atenolol inhibits the reaction [Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein]; Granisetron inhibits the reaction [Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein]; Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein CTD PMID:21173550 NCBI chr 2:201,317,916...201,326,487
Ensembl chr 2:201,317,920...201,326,532
JBrowse link
G Anxa11 annexin A11 increases expression ISO Lithium Chloride results in increased expression of ANXA11 mRNA CTD PMID:23527032 NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression ISO Lithium Chloride results in decreased expression of APC2 mRNA CTD PMID:23527032 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase increases expression ISO Lithium Chloride results in increased expression of APEH mRNA CTD PMID:23527032 NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Lithium Chloride inhibits the reaction [Copper affects the localization of APP protein] CTD PMID:24610780 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp2 aquaporin 2 decreases expression
multiple interactions
ISO
EXP
Lithium Chloride results in decreased expression of AQP2 mRNA; Lithium Chloride results in decreased expression of AQP2 protein
PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]
CTD PMID:18653713 PMID:19692487 PMID:21734099 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Arf6 ADP-ribosylation factor 6 increases expression ISO Lithium Chloride results in increased expression of ARF6 mRNA CTD PMID:15711924 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 increases expression ISO Lithium Chloride results in increased expression of ARHGAP29 mRNA CTD PMID:15711924 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 decreases expression ISO Lithium Chloride results in decreased expression of ASB1 mRNA CTD PMID:23527032 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Lithium Chloride results in increased expression of ATF4 mRNA CTD PMID:15711924 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp5me ATP synthase membrane subunit e decreases expression ISO Lithium Chloride results in decreased expression of ATP5ME mRNA CTD PMID:15711924 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Avp arginine vasopressin increases expression EXP Lithium Chloride results in increased expression of AVP mRNA; Lithium Chloride results in increased expression of AVP protein CTD PMID:9406968 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Axin2 axin 2 multiple interactions
increases expression
ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; Phenobarbital inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
CTD PMID:20694829 PMID:21498875 PMID:22493441 PMID:23326414 PMID:24534281 More... NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO Lithium Chloride results in increased expression of B4GALT1 mRNA CTD PMID:23527032 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein]
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX protein
Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of BAX protein]]; Lithium Chloride inhibits the reaction [Matrines results in increased expression of BAX protein]
CTD PMID:26074776 PMID:30171970 PMID:31220555 PMID:34813134 PMID:37075934 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Lithium Chloride results in increased expression of BCL2 mRNA; Lithium Chloride results in increased expression of BCL2 protein
Lithium Chloride inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
[Lithium Chloride results in increased abundance of Lithium] promotes the reaction [Paraquat results in increased expression of BCL2 mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 protein; [Paraquat co-treated with [Lithium Chloride results in increased abundance of Lithium]] results in increased expression of BCL2 protein
CTD PMID:17404573 PMID:18830594 PMID:19101580 PMID:19408126 PMID:26074776 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Lithium Chloride results in increased expression of BCL2L1 mRNA; Lithium Chloride results in increased expression of BCL2L1 protein CTD PMID:19101580 PMID:22493441 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Lithium Chloride results in increased expression of BCL3 mRNA CTD PMID:23527032 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased expression of BDNF mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased secretion of BDNF protein]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BDNF mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased secretion of BDNF protein CTD PMID:26074776 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions
affects expression
ISO Lithium Chloride affects the reaction [perfluorooctane sulfonic acid affects the expression of BGLAP mRNA]
Lithium Chloride affects the expression of BGLAP mRNA
CTD PMID:30738844 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression
EXP
ISO
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA]
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of BIRC5 protein]
Lithium Chloride results in increased expression of BIRC5 protein
CTD PMID:24464479 PMID:28886972 PMID:35985571 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO Lithium Chloride results in increased expression of BMP4 mRNA CTD PMID:15711924 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Lithium Chloride results in increased expression of BST2 mRNA CTD PMID:23527032 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Calr calreticulin decreases expression ISO Lithium Chloride results in decreased expression of CALR mRNA CTD PMID:26993217 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
ISO
EXP
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [fipronil results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
Lithium Chloride results in decreased activity of CASP3 protein
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]; Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
CTD PMID:19101580 PMID:21296133 PMID:21364661 PMID:24464479 PMID:26074776 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO Lithium Chloride results in increased expression of CASP4 mRNA CTD PMID:23527032 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form] CTD PMID:28886972 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] CTD PMID:28343033 PMID:28886972 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Lithium Chloride results in increased expression of CCL2 mRNA CTD PMID:33901603 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccna1 cyclin A1 increases expression
decreases expression
ISO Lithium Chloride results in increased expression of CCNA1 protein
Lithium Chloride results in decreased expression of CCNA1 mRNA
CTD PMID:19101580 PMID:23527032 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of CCNA2 mRNA; Lithium Chloride results in decreased expression of CCNA2 protein
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]
CTD PMID:15845746 PMID:17440966 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Lithium Chloride results in decreased expression of CCNB2 mRNA CTD PMID:15711924 PMID:17440966 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 affects localization
decreases expression
multiple interactions
decreases phosphorylation
increases expression
affects expression
ISO Lithium Chloride affects the localization of CCND1 protein
Lithium Chloride results in decreased expression of CCND1 protein
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of CCND1 protein]]; Lithium Chloride inhibits the reaction [baicalein results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in increased phosphorylation of CCND1 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of CCND1 mRNA]
Lithium Chloride results in decreased phosphorylation of CCND1 protein
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol affects the localization of CCND1 protein]]
Lithium Chloride results in increased expression of CCND1 mRNA; Lithium Chloride results in increased expression of CCND1 protein
Lithium Chloride affects the expression of CCND1 protein
CTD PMID:15753396 PMID:15845746 PMID:16024653 PMID:16076840 PMID:17440966 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Lithium Chloride results in increased expression of CCND2 mRNA CTD PMID:27226553 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Lithium Chloride results in increased expression of CCND3 mRNA CTD PMID:27226553 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne2 cyclin E2 decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CCNE2 mRNA; Lithium Chloride results in decreased expression of CCNE2 protein
Lithium Chloride results in increased expression of CCNE2 mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CCNG2 mRNA
Lithium Chloride results in increased expression of CCNG2 mRNA
CTD PMID:15711924 PMID:17440966 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cd40 CD40 molecule increases expression
multiple interactions
EXP Lithium Chloride results in increased expression of CD40 protein
rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of CD40 protein]
CTD PMID:18455351 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd44 CD44 molecule increases expression ISO Lithium Chloride results in increased expression of CD44 mRNA CTD PMID:23527032 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc25c cell division cycle 25C decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CDC25C mRNA; Lithium Chloride results in decreased expression of CDC25C protein
Lithium Chloride results in increased expression of CDC25C mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 decreases expression ISO Lithium Chloride results in decreased expression of CDC42EP2 mRNA CTD PMID:23527032 NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Lithium Chloride results in increased expression of CDC42SE1 mRNA CTD PMID:23527032 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CDC6 mRNA; Lithium Chloride results in decreased expression of CDC6 protein
Lithium Chloride results in increased expression of CDC6 mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdc7 cell division cycle 7 decreases expression ISO Lithium Chloride results in decreased expression of CDC7 mRNA CTD PMID:23527032 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO [Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in increased expression of CDH1 protein]; Lithium Chloride inhibits the reaction [taraxasterol inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]]; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in increased expression of CDH1 protein]
Lithium Chloride results in decreased expression of CDH1 protein
CTD PMID:20348013 PMID:22134133 PMID:32112862 PMID:34219514 PMID:35985571 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh11 cadherin 11 multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein] CTD PMID:19274078 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdh2 cadherin 2 decreases expression
increases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of CDH2 mRNA
Lithium Chloride results in increased expression of CDH2 protein
Lithium Chloride inhibits the reaction [taraxasterol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein]]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of CDH2 protein]
CTD PMID:23527032 PMID:32112862 PMID:34219514 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Lithium Chloride results in increased expression of CDKN1A mRNA; Lithium Chloride results in increased expression of CDKN1A protein CTD PMID:17440966 PMID:34624459 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO Lithium Chloride results in decreased expression of CDKN1B mRNA CTD PMID:17440966 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Lithium Chloride results in increased expression of CDKN1C mRNA CTD PMID:17440966 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Lithium Chloride results in increased expression of CDKN2A mRNA CTD PMID:23527032 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO Lithium Chloride results in increased expression of CDKN2B mRNA CTD PMID:23527032 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of CEBPA mRNA] CTD PMID:32494933 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Lithium Chloride results in increased expression of CEBPD mRNA CTD PMID:23527032 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 decreases expression ISO Lithium Chloride results in decreased expression of CELF2 mRNA CTD PMID:23527032 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
JBrowse link
G Cenpf centromere protein F decreases expression ISO Lithium Chloride results in decreased expression of CENPF mRNA CTD PMID:15711924 PMID:23527032 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cep250 centrosomal protein 250 decreases expression ISO Lithium Chloride results in decreased expression of CEP250 mRNA CTD PMID:23527032 NCBI chr 3:144,470,946...144,516,125
Ensembl chr 3:144,471,214...144,516,125
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist increases expression ISO Lithium Chloride results in increased expression of CER1 mRNA CTD PMID:26272751 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Cfd complement factor D increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of CFD mRNA
Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of CFD mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of CFD mRNA]
CTD PMID:23527032 PMID:28291828 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cftr CF transmembrane conductance regulator increases expression ISO Lithium Chloride results in increased expression of CFTR mRNA CTD PMID:23527032 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chga chromogranin A decreases expression ISO Lithium Chloride results in decreased expression of CHGA mRNA; Lithium Chloride results in decreased expression of CHGA protein CTD PMID:33901603 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chgb chromogranin B decreases expression ISO Lithium Chloride results in decreased expression of CHGB mRNA CTD PMID:33901603 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO Lithium Chloride results in increased expression of CHORDC1 mRNA CTD PMID:15711924 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Ckm creatine kinase, M-type increases expression ISO Lithium Chloride results in increased expression of CKM mRNA CTD PMID:20694829 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Cldn1 claudin 1 increases expression ISO Lithium Chloride results in increased expression of CLDN1 mRNA CTD PMID:33901603 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn12 claudin 12 decreases expression ISO Lithium Chloride results in decreased expression of CLDN12 mRNA CTD PMID:33901603 NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
JBrowse link
G Cldn15 claudin 15 decreases expression ISO Lithium Chloride results in decreased expression of CLDN15 mRNA; Lithium Chloride results in decreased expression of CLDN15 protein CTD PMID:33901603 NCBI chr12:19,698,167...19,708,419
Ensembl chr12:19,698,337...19,706,819
JBrowse link
G Clk2 CDC-like kinase 2 decreases expression ISO Lithium Chloride results in decreased expression of CLK2 mRNA CTD PMID:15711924 NCBI chr 2:174,570,614...174,582,645
Ensembl chr 2:174,570,653...174,588,985
JBrowse link
G Col13a1 collagen type XIII alpha 1 chain decreases expression ISO Lithium Chloride results in decreased expression of COL13A1 mRNA CTD PMID:23527032 NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032
JBrowse link
G Col1a2 collagen type I alpha 2 chain affects expression ISO Lithium Chloride affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression
increases phosphorylation
EXP
ISO
Lithium Chloride results in increased expression of CREB1 mRNA
Lithium Chloride results in increased phosphorylation of CREB1 protein
CTD PMID:18830594 PMID:19285016 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crisp2 cysteine-rich secretory protein 2 decreases expression ISO Lithium Chloride results in decreased expression of CRISP2 mRNA CTD PMID:15711924 NCBI chr 9:20,107,649...20,131,967
Ensembl chr 9:20,107,701...20,131,959
JBrowse link
G Ctcf CCCTC-binding factor increases expression EXP Lithium Chloride results in increased expression of CTCF mRNA CTD PMID:19285016 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases phosphorylation
increases activity
increases localization
increases expression
increases stability
affects localization
ISO
EXP
[Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of CTNNB1 protein]]; Hexachlorophene inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Aspirin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [celastrol results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Indomethacin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of and results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of and results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Lithium Chloride results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased localization of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased localization of and results in increased activity of CTNNB1 protein; MALAT1 protein affects the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]
Lithium Chloride results in decreased phosphorylation of CTNNB1 protein
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride results in increased expression of and affects the localization of CTNNB1 protein
Lithium Chloride results in increased localization of CTNNB1 protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein]
Lithium Chloride results in increased expression of CTNNB1 mRNA; Lithium Chloride results in increased expression of CTNNB1 protein
Lithium Chloride results in increased stability of CTNNB1 protein
Lithium Chloride affects the localization of CTNNB1 protein; Lithium Chloride affects the localization of CTNNB1 protein modified form
CTD PMID:12813129 PMID:15364539 PMID:16053526 PMID:16076840 PMID:16735606 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Lithium Chloride results in increased expression of CYP1A1 mRNA CTD PMID:21498875 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP Lithium Chloride promotes the reaction [Cadmium results in increased expression of DDIT3 protein] CTD PMID:27658547 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Diras3 DIRAS family GTPase 3 increases expression ISO Lithium Chloride results in increased expression of DIRAS3 mRNA CTD PMID:15711924 NCBI chr 6:130,524,972...130,526,186
Ensembl chr 6:130,524,742...130,530,825
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of DVL2 protein] CTD PMID:30171970 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
JBrowse link
G Ebf1 EBF transcription factor 1 increases expression ISO Lithium Chloride results in increased expression of EBF1 mRNA CTD PMID:27226553 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
JBrowse link
G Efna3 ephrin A3 decreases expression EXP Lithium Chloride results in decreased expression of EFNA3 mRNA CTD PMID:18772502 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
ISO [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA]
Lithium Chloride results in increased expression of EGFR mRNA; Lithium Chloride results in increased expression of EGFR protein
CTD PMID:22493441 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 decreases expression ISO Lithium Chloride results in decreased expression of ENOX2 mRNA CTD PMID:23527032 NCBI chr  X:128,270,941...128,593,074
Ensembl chr  X:128,271,074...128,593,039
JBrowse link
G Epha5 EPH receptor A5 decreases expression EXP Lithium Chloride results in decreased expression of EPHA5 mRNA; Lithium Chloride results in decreased expression of EPHA5 protein CTD PMID:18772502 NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]]; Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases expression ISO Lithium Chloride results in increased expression of ERBB3 mRNA CTD PMID:23527032 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression ISO Lithium Chloride results in increased expression of ERCC1 mRNA CTD PMID:15711924 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; Lithium Chloride inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Lithium Chloride inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein]; Lithium Chloride results in decreased phosphorylation of and results in decreased stability of and results in decreased expression of ESR1 protein CTD PMID:16076840 PMID:26990689 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esrrg estrogen-related receptor gamma increases expression ISO Lithium Chloride results in increased expression of ESRRG mRNA CTD PMID:23527032 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases expression
ISO Lithium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]
Lithium Chloride results in decreased expression of F3 mRNA
CTD PMID:15371228 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F5 coagulation factor V increases expression ISO Lithium Chloride results in increased expression of F5 mRNA CTD PMID:23527032 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fam90a1a family with sequence similarity 90 member A1A decreases expression ISO Lithium Chloride results in decreased expression of FAM90A1 mRNA CTD PMID:23527032 NCBI chr16:70,098,439...70,106,147
Ensembl chr16:70,098,740...70,101,241
JBrowse link
G Fbxo32 F-box protein 32 decreases expression ISO Lithium Chloride results in decreased expression of FBXO32 mRNA CTD PMID:21832246 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 multiple interactions ISO FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein] CTD PMID:25897075 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression EXP Lithium increases expression of Fgf21 mRNA in cerebellar granular cells and hippocampal and cortical neurons RGD PMID:24468826 RGD:10401923 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fmn2 formin 2 decreases expression ISO Lithium Chloride results in decreased expression of FMN2 mRNA CTD PMID:23527032 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP Butyrates promotes the reaction [Lithium Chloride results in increased expression of FOS protein] CTD PMID:20346924 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression ISO Lithium Chloride results in increased expression of FXYD5 mRNA CTD PMID:23527032 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein]; Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] CTD PMID:30926361 PMID:32763437 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Fzd3 frizzled class receptor 3 increases expression ISO Lithium Chloride results in increased expression of FZD3 mRNA CTD PMID:20069066 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of FZD4 mRNA
FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of CCND1 protein]]; FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of CTNNB1 protein]]; FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of MYC protein]]; FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of WNT5A protein]]
CTD PMID:20069066 PMID:34219513 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression ISO Lithium Chloride results in increased expression of FZD6 mRNA CTD PMID:20069066 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO GATA1 protein results in decreased susceptibility to [Lithium Chloride co-treated with Tretinoin] CTD PMID:19230972 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) increases expression ISO Lithium Chloride results in increased expression of GBGT1 mRNA CTD PMID:23527032 NCBI chr 3:11,826,131...11,829,745 JBrowse link
G Gcg glucagon multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]
Lithium Chloride results in increased expression of GCG mRNA
CTD PMID:19582394 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gda guanine deaminase increases expression ISO Lithium Chloride results in increased expression of GDA mRNA CTD PMID:23527032 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP protein; Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]
CTD PMID:23872260 PMID:31018114 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gip gastric inhibitory polypeptide multiple interactions
increases expression
ISO [[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter]
Lithium Chloride results in increased expression of GIP mRNA
CTD PMID:19582394 NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Gja1 gap junction protein, alpha 1 affects localization
multiple interactions
increases expression
EXP Lithium Chloride affects the localization of GJA1 protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein
Lithium Chloride results in increased expression of GJA1 protein
CTD PMID:18972237 PMID:21177194 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glb1 galactosidase, beta 1 increases activity ISO Lithium Chloride results in increased activity of GLB1 protein CTD PMID:34624459 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in decreased expression of GLUD1 mRNA] CTD PMID:32494933 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gnaz G protein subunit alpha z decreases expression ISO Lithium Chloride results in decreased expression of GNAZ mRNA CTD PMID:23527032 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
JBrowse link
G Gnpat glyceronephosphate O-acyltransferase decreases expression ISO Lithium Chloride results in decreased expression of GNPAT mRNA CTD PMID:23527032 NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
JBrowse link
G Gramd2a GRAM domain containing 2A increases expression ISO Lithium Chloride results in increased expression of GRAMD2A mRNA CTD PMID:23527032 NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842
JBrowse link
G Gramd2b GRAM domain containing 2B increases expression ISO Lithium Chloride results in increased expression of GRAMD2B mRNA CTD PMID:23527032 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
decreases expression
ISO [[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists; [Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA
Lithium Chloride results in decreased expression of GRIN1 mRNA
CTD PMID:19285052 PMID:34748853 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP [Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of GRM1 mRNA CTD PMID:32494933 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grn granulin precursor increases expression ISO Lithium Chloride results in increased expression of GRN mRNA CTD PMID:23527032 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions EXP Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3A protein] CTD PMID:27658547 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
affects phosphorylation
increases stability
decreases expression
decreases activity
increases phosphorylation
increases expression
ISO
EXP
[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in decreased expression of GSK3B protein modified form]; Lithium Chloride inhibits the reaction [celastrol results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [quinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein]; Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in decreased expression of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of and results in decreased activity of GSK3B protein; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein; PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]
Lithium Chloride results in decreased phosphorylation of GSK3B protein
Lithium Chloride affects the phosphorylation of GSK3B protein
Lithium Chloride results in increased stability of GSK3B protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride co-treated with Cisplatin] results in increased phosphorylation of GSK3B protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; calyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Lithium Chloride inhibits the reaction [Matrines results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium Chloride results in decreased expression of GSK3B mRNA
Lithium Chloride results in increased expression of GSK3B protein modified form
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cisplatin results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein
CTD PMID:12813129 PMID:15247282 PMID:15364539 PMID:15585669 PMID:15753396 More... NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA CTD PMID:20118494 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO Lithium Chloride results in decreased expression of H1-2 mRNA CTD PMID:15711924 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 increases expression ISO Lithium Chloride results in increased expression of HAPLN1 mRNA CTD PMID:23527032 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO Lithium Chloride results in decreased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Hdgfl3 HDGF like 3 decreases expression ISO Lithium Chloride results in decreased expression of HDGFL3 mRNA CTD PMID:15711924 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
JBrowse link
G Hes7 hes family bHLH transcription factor 7 increases expression ISO Lithium Chloride results in increased expression of HES7 mRNA CTD PMID:23326414 NCBI chr10:53,824,124...53,828,934
Ensembl chr10:53,825,574...53,828,097
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 protein] CTD PMID:32494933 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Lithium Chloride results in increased expression of HMOX1 mRNA
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of HMOX1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased expression of HMOX1 protein]
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of HMOX1 mRNA; Lithium Chloride promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]
CTD PMID:23527032 PMID:26074776 PMID:27658547 PMID:30672058 PMID:33645131 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A decreases expression ISO Lithium Chloride results in decreased expression of HSPA12A mRNA CTD PMID:23527032 NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form CTD PMID:20090934 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A decreases expression ISO Lithium Chloride results in decreased expression of HTR2A mRNA CTD PMID:23527032 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Ibsp integrin-binding sialoprotein decreases expression ISO Lithium Chloride results in decreased expression of IBSP mRNA CTD PMID:19442631 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Lithium Chloride results in increased expression of ICAM1 mRNA CTD PMID:23527032 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO Lithium Chloride results in decreased expression of ID3 mRNA CTD PMID:15711924 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein] CTD PMID:31760073 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ids iduronate 2-sulfatase increases expression ISO Lithium Chloride results in increased expression of IDS mRNA CTD PMID:23527032 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Ifng interferon gamma increases expression ISO Lithium Chloride results in increased expression of IFNG mRNA CTD PMID:9328138 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA] CTD PMID:19657059 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of IL1B protein
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B protein
Lithium Chloride results in increased expression of IL1B mRNA
CTD PMID:19010416 PMID:31018114 PMID:33901603 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO Lithium Chloride results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Lithium Chloride results in increased expression of IL6 mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 protein; Lithium Chloride inhibits the reaction [Valproic Acid results in increased expression of IL6 protein]
CTD PMID:9328138 PMID:31018114 PMID:36535311 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains increases expression ISO Lithium Chloride results in increased expression of ILRUN mRNA CTD PMID:23527032 NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Iqca1 IQ motif containing with AAA domain 1 increases expression ISO Lithium Chloride results in increased expression of IQCA1 mRNA CTD PMID:23527032 NCBI chr 9:90,626,735...90,742,563
Ensembl chr 9:90,626,744...90,742,618
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Lithium Chloride promotes the reaction [Tretinoin results in increased expression of ITGAM protein] CTD PMID:29743969 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb8 integrin subunit beta 8 increases expression ISO Lithium Chloride results in increased expression of ITGB8 mRNA CTD PMID:15711924 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Lithium Chloride results in increased expression of JDP2 mRNA CTD PMID:23527032 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Lithium Chloride results in decreased expression of JUN mRNA CTD PMID:26272751 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 decreases expression ISO Lithium Chloride results in decreased expression of KBTBD11 mRNA CTD PMID:23527032 NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736
JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 increases expression ISO Lithium Chloride results in increased expression of KCNK6 mRNA CTD PMID:23527032 NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases expression ISO Lithium Chloride results in increased expression of KCNN4 mRNA CTD PMID:23527032 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Lithium Chloride results in increased expression of KDR mRNA CTD PMID:26272751 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif5a kinesin family member 5A decreases expression ISO Lithium Chloride results in decreased expression of KIF5A mRNA CTD PMID:23527032 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
JBrowse link
G Krt19 keratin 19 increases expression ISO Lithium Chloride results in increased expression of KRT19 mRNA CTD PMID:23527032 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt34 keratin 34 increases expression ISO Lithium Chloride results in increased expression of KRT34 mRNA CTD PMID:15711924 NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040
JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO Lithium Chloride results in increased expression of LAMC1 mRNA CTD PMID:23527032 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression ISO Lithium Chloride results in increased expression of LCP1 mRNA CTD PMID:23527032 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 increases expression ISO Lithium Chloride results in increased expression of LGR5 mRNA CTD PMID:33901603 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
JBrowse link
G Lig4 DNA ligase 4 increases expression EXP Lithium Chloride results in increased expression of LIG4 mRNA; Lithium Chloride results in increased expression of LIG4 protein CTD PMID:19285016 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Lrp6 LDL receptor related protein 6 increases expression ISO Lithium Chloride results in increased expression of LRP6 mRNA CTD PMID:20069066 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Maged2 MAGE family member D2 decreases expression ISO Lithium Chloride results in decreased expression of MAGED2 mRNA CTD PMID:23527032 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation EXP Lithium Chloride affects the phosphorylation of MAPK1 protein CTD PMID:21364661 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk10 mitogen activated protein kinase 10 decreases expression ISO Lithium Chloride results in decreased expression of MAPK10 mRNA CTD PMID:23527032 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation EXP Lithium Chloride affects the phosphorylation of MAPK3 protein CTD PMID:21364661 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
decreases expression
EXP
ISO
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPT protein]
Lithium Chloride results in decreased expression of MAPT mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]
CTD PMID:20937724 PMID:23527032 PMID:27050422 PMID:35993674 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marveld2 MARVEL domain containing 2 increases expression ISO Lithium Chloride results in increased expression of MARVELD2 mRNA CTD PMID:23527032 NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Lithium Chloride results in increased expression of MCL1 mRNA; Lithium Chloride results in increased expression of MCL1 protein CTD PMID:22493441 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Lithium Chloride results in decreased expression of MCM2 mRNA CTD PMID:17440966 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO Lithium Chloride results in decreased expression of MCM4 mRNA CTD PMID:17440966 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Lithium Chloride results in decreased expression of MCM5 mRNA CTD PMID:17440966 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Lithium Chloride results in decreased expression of MCM6 mRNA CTD PMID:17440966 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Lithium Chloride results in decreased expression of MCM7 mRNA CTD PMID:17440966 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 increases expression ISO Lithium Chloride results in increased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Mex3b mex-3 RNA binding family member B decreases expression ISO Lithium Chloride results in decreased expression of MEX3B mRNA CTD PMID:23527032 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 decreases expression ISO Lithium Chloride results in decreased expression of MIB1 mRNA CTD PMID:23527032 NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
JBrowse link
G Mir152 microRNA 152 increases expression EXP Lithium Chloride results in increased expression of MIR152 mRNA CTD PMID:19254429 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
JBrowse link
G Mir155 microRNA 155 increases expression EXP Lithium Chloride results in increased expression of MIR155 mRNA CTD PMID:19254429 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir200c microRNA 200c multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] results in increased expression of MIR200C mRNA CTD PMID:31018114 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir221 microRNA 221 increases expression EXP Lithium Chloride results in increased expression of MIR221 mRNA CTD PMID:19254429 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir34a microRNA 34a multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of MIR34A mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of MIR34A mRNA CTD PMID:26074776 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir494 microRNA 494 decreases expression EXP Lithium Chloride results in decreased expression of MIR494 mRNA CTD PMID:19254429 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Lithium Chloride results in increased expression of MITF mRNA CTD PMID:23527032 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mixl1 Mix paired-like homeobox 1 increases expression ISO Lithium Chloride results in increased expression of MIXL1 mRNA CTD PMID:26272751 NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of MKI67 protein]] CTD PMID:15845746 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor decreases expression ISO Lithium Chloride results in decreased expression of MLLT11 mRNA CTD PMID:23527032 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mmab metabolism of cobalamin associated B decreases expression ISO Lithium Chloride results in decreased expression of MMAB mRNA CTD PMID:23527032 NCBI chr12:42,159,109...42,172,518
Ensembl chr12:42,159,089...42,172,490
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
increases expression
ISO MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MMP7 protein]; MALAT1 protein affects the reaction [resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein]]; resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein] CTD PMID:24244343 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mpz myelin protein zero multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ protein]
Lithium Chloride results in increased expression of MPZ mRNA; Lithium Chloride results in increased expression of MPZ protein
CTD PMID:27788593 NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 decreases expression ISO Lithium Chloride results in decreased expression of MRPL47 mRNA CTD PMID:15711924 NCBI chr 2:115,507,842...115,520,093
Ensembl chr 2:115,500,264...115,518,994
JBrowse link
G Msgn1 mesogenin 1 increases expression ISO Lithium Chloride results in increased expression of MSGN1 mRNA CTD PMID:23326414 NCBI chr 6:33,912,787...33,913,427
Ensembl chr 6:33,912,787...33,913,427
JBrowse link
G Msi1 musashi RNA-binding protein 1 increases expression ISO Lithium Chloride results in increased expression of MSI1 protein CTD PMID:20069066 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases expression
ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein]
Lithium Chloride results in decreased expression of MTOR mRNA
CTD PMID:30171970 PMID:34748853 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
affects expression
EXP
ISO
Lithium Chloride inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein]
Lithium Chloride results in increased expression of MYC mRNA; Lithium Chloride results in increased expression of MYC protein
Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]; FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of MYC protein]]; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of MYC protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of MYC protein]; Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of MYC protein]; MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]]
Lithium Chloride affects the expression of MYC protein
CTD PMID:19679347 PMID:22100782 PMID:22493441 PMID:24244343 PMID:26272751 More... NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myct1 myc target 1 increases expression ISO Lithium Chloride results in increased expression of MYCT1 mRNA CTD PMID:23527032 NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410
JBrowse link
G Myh4 myosin heavy chain 4 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of MYH4 mRNA
Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA]
CTD PMID:19657059 PMID:20694829 NCBI chr10:51,923,149...51,946,297
Ensembl chr10:51,885,913...51,946,295
JBrowse link
G Myh8 myosin heavy chain 8 increases expression ISO Lithium Chloride results in increased expression of MYH8 mRNA CTD PMID:20694829 NCBI chr10:51,963,510...51,993,103
Ensembl chr10:51,963,510...51,993,232
JBrowse link
G Myo1e myosin IE increases expression ISO Lithium Chloride results in increased expression of MYO1E mRNA CTD PMID:26272751 NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
JBrowse link
G Nanog Nanog homeobox increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of NANOG mRNA
Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of NANOG protein]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]
CTD PMID:20069066 PMID:37551626 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Lithium Chloride results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nes nestin increases expression ISO Lithium Chloride results in increased expression of NES mRNA CTD PMID:26272751 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Neurod1 neuronal differentiation 1 decreases expression ISO Lithium Chloride results in decreased expression of NEUROD1 mRNA CTD PMID:33901603 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 increases activity ISO Lithium Chloride results in increased activity of NFATC3 protein CTD PMID:20694829 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP
ISO
Lithium Chloride affects the reaction [triptolide affects the expression of NFE2L2 protein]; Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein]; Lithium Chloride inhibits the reaction [Matrines results in decreased expression of NFE2L2 protein]
[Lithium Chloride results in increased abundance of Lithium] which affects the localization of NFE2L2 protein; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NFE2L2 mRNA
CTD PMID:26074776 PMID:30926361 PMID:32763437 PMID:37075934 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation ISO Lithium Chloride results in increased degradation of NFKBIA protein CTD PMID:24085292 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nhlh1 nescient helix loop helix 1 decreases expression ISO Lithium Chloride results in decreased expression of NHLH1 mRNA CTD PMID:23527032 NCBI chr13:84,517,347...84,522,548
Ensembl chr13:84,517,289...84,525,094
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of NKD1 mRNA
Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]
CTD PMID:24534281 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression EXP Lithium Chloride results in increased expression of NOS1 mRNA CTD PMID:9500967 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO Lithium Chloride results in increased expression of NOS2 mRNA CTD PMID:19679347 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Lithium Chloride results in decreased expression of NOTCH1 mRNA CTD PMID:23527032 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Npepl1 aminopeptidase-like 1 increases expression ISO Lithium Chloride results in increased expression of NPEPL1 mRNA CTD PMID:23527032 NCBI chr 3:162,893,932...162,906,491
Ensembl chr 3:162,893,943...162,906,492
JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]] CTD PMID:34813134 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO
EXP
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NQO1 mRNA
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NQO1 protein]]
CTD PMID:26074776 PMID:33645131 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 protein] CTD PMID:32494933 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions
increases expression
EXP CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of NR4A2 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein]
Lithium Chloride results in increased expression of NR4A2 mRNA; Lithium Chloride results in increased expression of NR4A2 protein
CTD PMID:27045591 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO Lithium Chloride results in decreased expression of NRCAM mRNA CTD PMID:26272751 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 decreases expression ISO Lithium Chloride results in decreased expression of NSD2 mRNA CTD PMID:23527032 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Ntn1 netrin 1 decreases expression ISO Lithium Chloride results in decreased expression of NTN1 mRNA CTD PMID:23527032 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
JBrowse link
G Ocln occludin decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of OCLN mRNA
Lithium Chloride results in increased expression of OCLN protein
CTD PMID:33901603 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Oprm1 opioid receptor, mu 1 decreases expression EXP Lithium Chloride results in decreased expression of OPRM1 protein CTD PMID:17919468 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP
ISO
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; [Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]
Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]
CTD PMID:27658547 PMID:28343033 PMID:28886972 PMID:30377735 PMID:31396050 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax3 paired box 3 increases expression ISO Lithium Chloride results in increased expression of PAX3 protein CTD PMID:19101580 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
decreases expression
EXP Lithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]; Lithium Chloride inhibits the reaction [Dexamethasone results in increased expression of PCK1 mRNA]
Lithium Chloride results in decreased expression of PCK1 mRNA
CTD PMID:1371108 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of PCNA protein]]
Lithium Chloride results in increased expression of PCNA protein
CTD PMID:15845746 PMID:27018151 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression ISO Lithium Chloride results in decreased expression of PDE4B mRNA CTD PMID:23527032 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like increases expression ISO Lithium Chloride results in increased expression of PDGFRL mRNA CTD PMID:23527032 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Lithium Chloride results in increased expression of PDIA5 mRNA CTD PMID:23527032 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression ISO Lithium Chloride results in increased expression of PDLIM5 mRNA CTD PMID:15711924 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 multiple interactions EXP [Pilocarpine co-treated with Lithium Chloride co-treated with 3-chloroacetylindole] results in decreased phosphorylation of PEA15 protein; [Pilocarpine co-treated with Lithium Chloride] results in decreased phosphorylation of PEA15 protein CTD PMID:31396050 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Pigr polymeric immunoglobulin receptor decreases expression ISO Lithium Chloride results in decreased expression of PIGR mRNA CTD PMID:33901603 NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions
affects response to substance
increases response to substance
ISO PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]
PIK3CA protein affects the susceptibility to Lithium Chloride
PIK3CA protein mutant form results in increased susceptibility to Lithium Chloride
CTD PMID:19196980 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Lithium Chloride results in increased expression of PITPNB mRNA CTD PMID:15711924 NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 decreases expression ISO Lithium Chloride results in decreased expression of PLAGL1 mRNA CTD PMID:23527032 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plau plasminogen activator, urokinase decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of PLAU mRNA
Lithium Chloride results in increased expression of PLAU mRNA
CTD PMID:15711924 PMID:23527032 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pld1 phospholipase D1 increases expression ISO Lithium Chloride results in increased expression of PLD1 mRNA CTD PMID:23527032 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plekha6 pleckstrin homology domain containing A6 decreases expression ISO Lithium Chloride results in decreased expression of PLEKHA6 mRNA CTD PMID:23527032 NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of PLIN1 mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of PLIN1 mRNA] CTD PMID:28291828 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Plpp2 phospholipid phosphatase 2 increases expression ISO Lithium Chloride results in increased expression of PLPP2 mRNA CTD PMID:23527032 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Lithium Chloride results in increased expression of PMAIP1 mRNA; Lithium Chloride results in increased expression of PMAIP1 protein CTD PMID:15711924 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmel premelanosome protein increases expression ISO Lithium Chloride results in increased expression of PMEL mRNA CTD PMID:23527032 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 protein]
Lithium Chloride results in increased expression of PMP22 mRNA; Lithium Chloride results in increased expression of PMP22 protein
CTD PMID:27788593 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Polr3b RNA polymerase III subunit B decreases expression ISO Lithium Chloride results in decreased expression of POLR3B mRNA CTD PMID:23527032 NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598
JBrowse link
G Popdc3 popeye domain containing 3 increases expression ISO Lithium Chloride results in increased expression of POPDC3 mRNA CTD PMID:15711924 NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions
increases expression
ISO CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased expression of POU5F1 protein]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]
Lithium Chloride results in increased expression of POU5F1 mRNA; Lithium Chloride results in increased expression of POU5F1 protein
CTD PMID:20069066 PMID:20074550 PMID:37551626 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Lithium Chloride results in increased expression of PPARG mRNA CTD PMID:23527032 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H increases expression ISO Lithium Chloride results in increased expression of PPM1H mRNA CTD PMID:23527032 NCBI chr 7:58,338,661...58,599,547
Ensembl chr 7:58,338,661...58,599,547
JBrowse link
G Ppp1r14c protein phosphatase 1, regulatory (inhibitor) subunit 14c decreases expression ISO Lithium Chloride results in decreased expression of PPP1R14C mRNA CTD PMID:23527032 NCBI chr 1:39,773,403...39,886,970
Ensembl chr 1:39,773,403...39,886,956
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha increases expression ISO Lithium Chloride results in increased expression of PPP3R1 mRNA CTD PMID:15711924 NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Prr16 proline rich 16 decreases expression ISO Lithium Chloride results in decreased expression of PRR16 mRNA CTD PMID:15711924 NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329
JBrowse link
G Psme1 proteasome activator subunit 1 increases expression ISO Lithium Chloride results in increased expression of PSME1 mRNA CTD PMID:23527032 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
JBrowse link
G Ptges prostaglandin E synthase increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of PTGES protein
[Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]
CTD PMID:19692487 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO
EXP
Lithium Chloride results in increased expression of PTGS2 mRNA; Lithium Chloride results in increased expression of PTGS2 protein CTD PMID:9500967 PMID:15585669 PMID:15711924 PMID:19797860 PMID:24085292 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptx3 pentraxin 3 decreases expression ISO Lithium Chloride results in decreased expression of PTX3 mRNA CTD PMID:23527032 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Purg purine-rich element binding protein G decreases expression ISO Lithium Chloride results in decreased expression of PURG mRNA CTD PMID:23527032 NCBI chr16:58,732,327...58,763,356
Ensembl chr16:58,720,335...58,763,359
JBrowse link
G Pxn paxillin increases expression ISO Lithium Chloride results in increased expression of PXN mRNA CTD PMID:23527032 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Pycard PYD and CARD domain containing increases expression ISO Lithium Chloride results in increased expression of PYCARD mRNA CTD PMID:23527032 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rab23 RAB23, member RAS oncogene family increases expression ISO Lithium Chloride results in increased expression of RAB23 mRNA CTD PMID:15711924 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]]
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein]
CTD PMID:15845746 PMID:22820424 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO Lithium Chloride results in increased expression of RCAN1 mRNA CTD PMID:15711924 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK mRNA; [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK protein CTD PMID:31018114 NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
decreases phosphorylation
EXP
ISO
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; [Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]
Lithium Chloride results in increased phosphorylation of RELA protein
Lithium Chloride results in decreased phosphorylation of RELA protein
CTD PMID:24085292 PMID:31396050 PMID:33901603 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rexo2 RNA exonuclease 2 increases expression ISO Lithium Chloride results in increased expression of REXO2 mRNA CTD PMID:23527032 NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression ISO Lithium Chloride results in increased expression of RGS4 mRNA; Lithium Chloride results in increased expression of RGS4 protein CTD PMID:15711924 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein]; Lithium Chloride results in increased expression of and results in decreased ubiquitination of RICTOR protein CTD PMID:25897075 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression ISO Lithium Chloride results in increased expression of RND3 mRNA CTD PMID:15711924 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rnf144b ring finger protein 144B multiple interactions
increases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein]; Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein] CTD PMID:29724995 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760
JBrowse link
G Rnf40 ring finger protein 40 increases expression EXP Lithium Chloride results in increased expression of RNF40 protein CTD PMID:21734099 NCBI chr 1:182,202,475...182,217,899
Ensembl chr 1:182,202,600...182,217,241
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Lithium Chloride results in increased expression of RRAD mRNA CTD PMID:15711924 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Rtn1 reticulon 1 decreases expression ISO Lithium Chloride results in decreased expression of RTN1 mRNA CTD PMID:23527032 NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
JBrowse link
G S100a3 S100 calcium binding protein A3 increases expression ISO Lithium Chloride results in increased expression of S100A3 mRNA CTD PMID:23527032 NCBI chr 2:176,034,283...176,089,702
Ensembl chr 2:176,049,520...176,089,702
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity ISO Lithium Chloride results in decreased activity of SCN5A protein CTD PMID:16144991 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha increases expression ISO Lithium Chloride results in increased expression of SCNN1A mRNA CTD PMID:23527032 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression ISO Lithium Chloride results in increased expression of SCPEP1 mRNA CTD PMID:23527032 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of SFRP2 mRNA
SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]
CTD PMID:20069066 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 decreases expression ISO Lithium Chloride results in decreased expression of SHANK2 mRNA CTD PMID:34748853 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
JBrowse link
G Shf Src homology 2 domain containing F decreases expression ISO Lithium Chloride results in decreased expression of SHF mRNA CTD PMID:23527032 NCBI chr 3:109,296,517...109,316,315
Ensembl chr 3:109,296,784...109,316,328
JBrowse link
G Shh sonic hedgehog signaling molecule decreases expression ISO Lithium Chloride results in decreased expression of SHH mRNA CTD PMID:26272751 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Shpk sedoheptulokinase increases expression ISO Lithium Chloride results in increased expression of SHPK mRNA CTD PMID:23527032 NCBI chr10:57,817,551...57,841,981
Ensembl chr10:57,817,629...57,841,980
JBrowse link
G Six1 SIX homeobox 1 increases expression
increases response to substance
ISO Lithium Chloride results in increased expression of SIX1 mRNA; Lithium Chloride results in increased expression of SIX1 protein
SIX1 protein results in increased susceptibility to Lithium Chloride
CTD PMID:19101580 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of SLC12A1 protein
PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]
CTD PMID:19692487 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc20a1 solute carrier family 20 member 1 increases expression ISO Lithium Chloride results in increased expression of SLC20A1 mRNA CTD PMID:15711924 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Lithium Chloride results in increased expression of SLC3A2 mRNA CTD PMID:15711924 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression ISO Lithium Chloride results in increased expression of SLC5A3 mRNA CTD PMID:15711924 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc6a4 solute carrier family 6 member 4 decreases expression ISO Lithium Chloride results in decreased expression of SLC6A4 mRNA CTD PMID:34748853 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP Lithium Chloride inhibits the reaction [citronellal inhibits the reaction [Doxorubicin results in increased expression of NHE1 protein]] CTD PMID:34813134 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases degradation
multiple interactions
ISO Lithium Chloride results in decreased degradation of SNAI1 protein
[Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein; Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of SNAI1 protein]
[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein
CTD PMID:19440036 PMID:20348013 PMID:35985571 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of SNAI2 protein] CTD PMID:35985571 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Snca synuclein alpha increases expression ISO Lithium Chloride results in increased expression of SNCA mRNA CTD PMID:23527032 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in decreased activity of SOD2 protein] CTD PMID:31760073 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO Lithium Chloride results in decreased expression of SPAG5 mRNA CTD PMID:23527032 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Sqor sulfide quinone oxidoreductase increases expression ISO Lithium Chloride results in increased expression of SQOR mRNA CTD PMID:23527032 NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Lithium Chloride promotes the reaction [Cisplatin results in decreased expression of SQSTM1 protein] CTD PMID:31220555 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Stard7 StAR-related lipid transfer domain containing 7 multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein CTD PMID:19679347 NCBI chr 3:114,487,161...114,515,828
Ensembl chr 3:114,485,600...114,515,813
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO Lithium Chloride results in increased expression of STAT6 mRNA CTD PMID:23527032 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 increases expression ISO Lithium Chloride results in increased expression of TARS1 mRNA CTD PMID:15711924 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression ISO Lithium Chloride results in decreased expression of TBC1D8 mRNA CTD PMID:15711924 NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409
JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]] CTD PMID:22935447 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tcf7l2 transcription factor 7 like 2 multiple interactions ISO Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Lithium Chloride inhibits the reaction [taraxasterol inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]]; Lithium Chloride inhibits the reaction [taraxasterol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein]] CTD PMID:34219514 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Lithium Chloride results in increased expression of TGFBR2 mRNA CTD PMID:23527032 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO Lithium Chloride results in decreased expression of TJP1 mRNA CTD PMID:33901603 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of TLR4 mRNA] CTD PMID:32494933 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO Lithium Chloride results in increased expression of TM4SF1 mRNA CTD PMID:15711924 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
JBrowse link
G Tnc tenascin C increases expression ISO Lithium Chloride results in increased expression of TNC mRNA CTD PMID:15711924 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of TNF protein
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF protein; Rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of TNF protein]
Lithium Chloride results in increased expression of TNF mRNA
CTD PMID:18455351 PMID:31018114 PMID:33901603 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type increases expression ISO Lithium Chloride results in increased expression of TNNC1 mRNA CTD PMID:23527032 NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression ISO Lithium Chloride results in increased expression of TNNT1 mRNA CTD PMID:23527032 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Top3a DNA topoisomerase III alpha decreases expression ISO Lithium Chloride results in decreased expression of TOP3A mRNA CTD PMID:23527032 NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of TP53 protein
Lithium Chloride results in decreased degradation of and results in increased expression of TRP53 protein
CTD PMID:16055726 PMID:17210701 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 increases expression ISO Lithium Chloride results in increased expression of TP63 mRNA CTD PMID:23527032 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tpd52l1 TPD52 like 1 increases expression ISO Lithium Chloride results in increased expression of TPD52L1 mRNA CTD PMID:23527032 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Tph1 tryptophan hydroxylase 1 decreases expression ISO Lithium Chloride results in decreased expression of TPH1 mRNA CTD PMID:33901603 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
G Tph2 tryptophan hydroxylase 2 decreases expression EXP Lithium Chloride results in decreased expression of TPH2 mRNA; Lithium Chloride results in decreased expression of TPH2 protein CTD PMID:19840776 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
JBrowse link
G Tpm1 tropomyosin 1 increases expression ISO Lithium Chloride results in increased expression of TPM1 mRNA CTD PMID:23527032 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Lithium Chloride results in increased expression of TRIB3 mRNA CTD PMID:23527032 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim6 tripartite motif containing 6 increases expression ISO Lithium Chloride results in increased expression of TRIM6 mRNA CTD PMID:23527032 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of UGCG mRNA
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of UGCG mRNA
CTD PMID:15711924 PMID:26074776 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Utp3 UTP3, small subunit processome component increases expression ISO Lithium Chloride results in increased expression of UTP3 mRNA CTD PMID:27226553 NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO Lithium Chloride results in increased expression of VCAM1 mRNA CTD PMID:33901603 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcf2 VCP nuclear cofactor family member 2 decreases expression ISO Lithium Chloride results in decreased expression of VCF2 mRNA CTD PMID:23527032 NCBI chr  X:19,310,182...19,393,156
Ensembl chr  X:19,349,560...19,378,486
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Lithium Chloride results in increased expression of VEGFA protein
Lithium Chloride results in increased expression of VEGFA mRNA
CTD PMID:20696143 PMID:26272751 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin increases expression
decreases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of VIM protein
Lithium Chloride results in decreased expression of VIM mRNA
Lithium Chloride inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in decreased expression of VIM protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of VIM protein]
CTD PMID:8773480 PMID:23527032 PMID:32112862 PMID:35985571 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vpreb1a V-set pre-B cell surrogate light chain 1A increases expression ISO Lithium Chloride results in increased expression of VPREB1 mRNA CTD PMID:27226553 NCBI chr11:84,126,969...84,127,846
Ensembl chr11:84,126,969...84,127,846
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of WNT1 protein] CTD PMID:28343033 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt3 Wnt family member 3 decreases expression ISO Lithium Chloride results in decreased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
G Wnt5a Wnt family member 5A multiple interactions ISO FZD4 protein promotes the reaction [Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of WNT5A protein]]; Lithium Chloride inhibits the reaction [Quercetin results in decreased expression of WNT5A protein] CTD PMID:34219513 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 increases expression EXP Lithium Chloride results in increased expression of XRCC4 mRNA CTD PMID:19285016 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
G Ybx1 Y box binding protein 1 decreases expression ISO Lithium Chloride results in decreased expression of YBX1 mRNA CTD PMID:23527032 NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Zfp207 zinc finger protein 207 increases expression ISO Lithium Chloride results in increased expression of ZNF207 mRNA CTD PMID:15711924 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
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G Zfp423 zinc finger protein 423 decreases expression ISO Lithium Chloride results in decreased expression of ZNF423 mRNA CTD PMID:23527032 NCBI chr19:19,111,213...19,407,373
Ensembl chr19:19,110,238...19,407,373
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G Zmynd8 zinc finger, MYND-type containing 8 decreases expression ISO Lithium Chloride results in decreased expression of ZMYND8 mRNA CTD PMID:15711924 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
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G Zscan22 zinc finger and SCAN domain containing 22 decreases expression ISO Lithium Chloride results in decreased expression of ZSCAN22 mRNA CTD PMID:23527032 NCBI chr 1:73,516,328...73,527,766
Ensembl chr 1:73,516,395...73,527,697
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      application 19734
        NMR chemical shift reference compound 18103
          lithium chloride 351
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      halogen 18718
                        chlorine atom 18500
                          chlorine molecular entity 18500
                            elemental chlorine 8796
                              monoatomic chlorine 8781
                                chloride 8781
                                  chloride salt 8781
                                    inorganic chloride 8545
                                      lithium chloride 351
paths to the root