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G |
A2ml1 |
alpha-2-macroglobulin-like 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of OVOS2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 4:161,815,111...161,857,286
Ensembl chr 4:161,814,708...161,857,343
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G |
Abat |
4-aminobutyrate aminotransferase |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ABAT mRNA |
CTD |
PMID:15711924 |
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NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases expression |
ISO |
Lithium Chloride results in increased expression of ABCB1 protein |
CTD |
PMID:18624906 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abhd11 |
abhydrolase domain containing 11 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ABHD11 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398
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G |
Abi2 |
abl-interactor 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ABI2 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ACADM mRNA; Lithium Chloride results in decreased expression of ACADM protein |
CTD |
PMID:26993217 |
|
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE protein] |
CTD |
PMID:32494933 |
|
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ache |
acetylcholinesterase |
multiple interactions increases degradation decreases stability |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein |
CTD |
PMID:22944069 |
|
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Adgrb3 |
adhesion G protein-coupled receptor B3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ADGRB3 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855
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G |
Adgre5 |
adhesion G protein-coupled receptor E5 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ADGRE5 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
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G |
Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] |
CTD |
PMID:32494933 |
|
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Agtr2 |
angiotensin II receptor, type 2 |
multiple interactions |
EXP |
[Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of AGTR2 mRNA |
CTD |
PMID:32494933 |
|
NCBI chr X:112,119,673...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA |
CTD |
PMID:21498875 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO EXP |
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein] [Lithium Chloride co-treated with Pilocarpine] results in increased phosphorylation of AKT1 protein |
CTD |
PMID:22820424 PMID:31018114 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ALDH1A3 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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G |
Alox5ap |
arachidonate 5-lipoxygenase activating protein |
increases expression |
ISO |
Lithium Chloride results in increased expression of ALOX5AP mRNA |
CTD |
PMID:23527032 |
|
NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
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G |
Alpg |
alkaline phosphatase, germ cell |
increases expression |
ISO |
Lithium Chloride results in increased expression of ALPG mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836
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G |
Alpp |
alkaline phosphatase, placental |
increases activity |
ISO |
Lithium Chloride results in increased activity of ALPP protein |
CTD |
PMID:16053526 |
|
NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
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G |
Amy1 |
amylase alpha 1 |
multiple interactions |
EXP |
Atenolol inhibits the reaction [Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein]; Granisetron inhibits the reaction [Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein]; Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein |
CTD |
PMID:21173550 |
|
NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816
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G |
Anxa11 |
annexin A11 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ANXA11 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797
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G |
Apc2 |
APC regulator of WNT signaling pathway 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of APC2 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
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G |
Apeh |
acylaminoacyl-peptide hydrolase |
increases expression |
ISO |
Lithium Chloride results in increased expression of APEH mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [Copper affects the localization of APP protein] |
CTD |
PMID:24610780 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp2 |
aquaporin 2 |
decreases expression multiple interactions |
ISO EXP |
Lithium Chloride results in decreased expression of AQP2 mRNA; Lithium Chloride results in decreased expression of AQP2 protein PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein] |
CTD |
PMID:18653713 PMID:19692487 PMID:21734099 |
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NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
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G |
Arf6 |
ADP-ribosylation factor 6 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ARF6 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
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G |
Arhgap29 |
Rho GTPase activating protein 29 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ARHGAP29 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
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G |
Asb1 |
ankyrin repeat and SOCS box-containing 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ASB1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
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G |
Atf4 |
activating transcription factor 4 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ATF4 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atp5me |
ATP synthase membrane subunit e |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ATP5ME mRNA |
CTD |
PMID:15711924 |
|
NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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G |
Avp |
arginine vasopressin |
increases expression |
EXP |
Lithium Chloride results in increased expression of AVP mRNA; Lithium Chloride results in increased expression of AVP protein |
CTD |
PMID:9406968 |
|
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Axin2 |
axin 2 |
multiple interactions increases expression |
ISO |
[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; Phenobarbital inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA] Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA] |
CTD |
PMID:20694829 PMID:21498875 PMID:22493441 PMID:23326414 PMID:24534281 PMID:27693619 More...
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NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
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G |
B4galt1 |
beta-1,4-galactosyltransferase 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of B4GALT1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein] [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX protein |
CTD |
PMID:26074776 PMID:30171970 PMID:31220555 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
Lithium Chloride results in increased expression of BCL2 mRNA; Lithium Chloride results in increased expression of BCL2 protein Lithium Chloride inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein] Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein] [Lithium Chloride results in increased abundance of Lithium] promotes the reaction [Paraquat results in increased expression of BCL2 mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 protein; [Paraquat co-treated with [Lithium Chloride results in increased abundance of Lithium]] results in increased expression of BCL2 protein |
CTD |
PMID:17404573 PMID:18830594 PMID:19101580 PMID:19408126 PMID:26074776 PMID:30171970 PMID:30926361 PMID:31220555 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of BCL2L1 mRNA; Lithium Chloride results in increased expression of BCL2L1 protein |
CTD |
PMID:19101580 PMID:22493441 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl3 |
BCL3, transcription coactivator |
increases expression |
ISO |
Lithium Chloride results in increased expression of BCL3 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased expression of BDNF mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased secretion of BDNF protein]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BDNF mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased secretion of BDNF protein |
CTD |
PMID:26074776 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions affects expression |
ISO |
Lithium Chloride affects the reaction [perfluorooctane sulfonic acid affects the expression of BGLAP mRNA] Lithium Chloride affects the expression of BGLAP mRNA |
CTD |
PMID:30738844 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions |
EXP ISO |
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA] Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein] |
CTD |
PMID:24464479 PMID:28886972 |
|
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmp4 |
bone morphogenetic protein 4 |
increases expression |
ISO |
Lithium Chloride results in increased expression of BMP4 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bst2 |
bone marrow stromal cell antigen 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of BST2 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CALR mRNA |
CTD |
PMID:26993217 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Casp3 |
caspase 3 |
multiple interactions decreases activity |
ISO EXP |
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [fipronil results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Staurosporine results in increased activity of CASP3 protein] Lithium Chloride results in decreased activity of CASP3 protein Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein] |
CTD |
PMID:19101580 PMID:21296133 PMID:21364661 PMID:24464479 PMID:26074776 PMID:27045591 PMID:28343033 PMID:28886972 PMID:30377735 PMID:30926361 PMID:33645131 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CASP4 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp7 |
caspase 7 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form] |
CTD |
PMID:28886972 |
|
NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] |
CTD |
PMID:28343033 PMID:28886972 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CCL2 mRNA |
CTD |
PMID:33901603 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccna1 |
cyclin A1 |
increases expression decreases expression |
ISO |
Lithium Chloride results in increased expression of CCNA1 protein Lithium Chloride results in decreased expression of CCNA1 mRNA |
CTD |
PMID:19101580 PMID:23527032 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccna2 |
cyclin A2 |
decreases expression multiple interactions |
ISO |
Lithium Chloride results in decreased expression of CCNA2 mRNA; Lithium Chloride results in decreased expression of CCNA2 protein Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]] |
CTD |
PMID:15845746 PMID:17440966 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb2 |
cyclin B2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CCNB2 mRNA |
CTD |
PMID:15711924 PMID:17440966 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
affects localization decreases expression multiple interactions decreases phosphorylation increases expression |
ISO |
Lithium Chloride affects the localization of CCND1 protein Lithium Chloride results in decreased expression of CCND1 protein [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [baicalein results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in increased phosphorylation of CCND1 protein]; Lithium Chloride inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of CCND1 mRNA] Lithium Chloride results in decreased phosphorylation of CCND1 protein Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol affects the localization of CCND1 protein]] Lithium Chloride results in increased expression of CCND1 mRNA; Lithium Chloride results in increased expression of CCND1 protein |
CTD |
PMID:15753396 PMID:15845746 PMID:16024653 PMID:16076840 PMID:17440966 PMID:19196980 PMID:19403565 PMID:20074550 PMID:22493441 PMID:22820424 PMID:27018151 PMID:27424123 PMID:28886972 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CCND2 mRNA |
CTD |
PMID:27226553 |
|
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccnd3 |
cyclin D3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CCND3 mRNA |
CTD |
PMID:27226553 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne2 |
cyclin E2 |
decreases expression increases expression |
ISO |
Lithium Chloride results in decreased expression of CCNE2 mRNA; Lithium Chloride results in decreased expression of CCNE2 protein Lithium Chloride results in increased expression of CCNE2 mRNA |
CTD |
PMID:17440966 PMID:22493441 |
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NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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G |
Ccng2 |
cyclin G2 |
decreases expression increases expression |
ISO |
Lithium Chloride results in decreased expression of CCNG2 mRNA Lithium Chloride results in increased expression of CCNG2 mRNA |
CTD |
PMID:15711924 PMID:17440966 |
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NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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G |
Cd40 |
CD40 molecule |
increases expression multiple interactions |
EXP |
Lithium Chloride results in increased expression of CD40 protein rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of CD40 protein] |
CTD |
PMID:18455351 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd44 |
CD44 molecule (Indian blood group) |
increases expression |
ISO |
Lithium Chloride results in increased expression of CD44 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cdc25c |
cell division cycle 25C |
decreases expression increases expression |
ISO |
Lithium Chloride results in decreased expression of CDC25C mRNA; Lithium Chloride results in decreased expression of CDC25C protein Lithium Chloride results in increased expression of CDC25C mRNA |
CTD |
PMID:17440966 PMID:22493441 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdc42ep2 |
CDC42 effector protein 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CDC42EP2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
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G |
Cdc42se1 |
CDC42 small effector 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CDC42SE1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
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G |
Cdc6 |
cell division cycle 6 |
decreases expression increases expression |
ISO |
Lithium Chloride results in decreased expression of CDC6 mRNA; Lithium Chloride results in decreased expression of CDC6 protein Lithium Chloride results in increased expression of CDC6 mRNA |
CTD |
PMID:17440966 PMID:22493441 |
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NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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G |
Cdc7 |
cell division cycle 7 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CDC7 mRNA |
CTD |
PMID:23527032 |
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NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO |
[Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in increased expression of CDH1 protein] Lithium Chloride results in decreased expression of CDH1 protein |
CTD |
PMID:20348013 PMID:22134133 PMID:32112862 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh11 |
cadherin 11 |
multiple interactions |
ISO |
[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein] |
CTD |
PMID:19274078 |
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NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
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G |
Cdh2 |
cadherin 2 |
decreases expression increases expression multiple interactions |
ISO |
Lithium Chloride results in decreased expression of CDH2 mRNA Lithium Chloride results in increased expression of CDH2 protein Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of CDH2 protein] |
CTD |
PMID:23527032 PMID:32112862 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Lithium Chloride results in increased expression of CDKN1A mRNA; Lithium Chloride results in increased expression of CDKN1A protein |
CTD |
PMID:17440966 PMID:34624459 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CDKN1B mRNA |
CTD |
PMID:17440966 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
increases expression |
ISO |
Lithium Chloride results in increased expression of CDKN1C mRNA |
CTD |
PMID:17440966 |
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NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases expression |
ISO |
Lithium Chloride results in increased expression of CDKN2A mRNA |
CTD |
PMID:23527032 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
increases expression |
ISO |
Lithium Chloride results in increased expression of CDKN2B mRNA |
CTD |
PMID:23527032 |
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NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of CEBPA mRNA] |
CTD |
PMID:32494933 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
increases expression |
ISO |
Lithium Chloride results in increased expression of CEBPD mRNA |
CTD |
PMID:23527032 |
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NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Celf2 |
CUGBP, Elav-like family member 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CELF2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
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G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CENPF mRNA |
CTD |
PMID:15711924 PMID:23527032 |
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NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Cep250 |
centrosomal protein 250 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CEP250 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:144,470,946...144,516,125
Ensembl chr 3:144,471,214...144,516,125
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G |
Cer1 |
cerberus 1, DAN family BMP antagonist |
increases expression |
ISO |
Lithium Chloride results in increased expression of CER1 mRNA |
CTD |
PMID:26272751 |
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NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
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G |
Cfd |
complement factor D |
increases expression multiple interactions |
ISO |
Lithium Chloride results in increased expression of CFD mRNA Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of CFD mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of CFD mRNA] |
CTD |
PMID:23527032 PMID:28291828 |
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NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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G |
Cftr |
CF transmembrane conductance regulator |
increases expression |
ISO |
Lithium Chloride results in increased expression of CFTR mRNA |
CTD |
PMID:23527032 |
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NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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G |
Chga |
chromogranin A |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CHGA mRNA; Lithium Chloride results in decreased expression of CHGA protein |
CTD |
PMID:33901603 |
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NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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G |
Chgb |
chromogranin B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CHGB mRNA |
CTD |
PMID:33901603 |
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NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
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G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CHORDC1 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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G |
Ckm |
creatine kinase, M-type |
increases expression |
ISO |
Lithium Chloride results in increased expression of CKM mRNA |
CTD |
PMID:20694829 |
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NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
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G |
Cldn1 |
claudin 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CLDN1 mRNA |
CTD |
PMID:33901603 |
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NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn12 |
claudin 12 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CLDN12 mRNA |
CTD |
PMID:33901603 |
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NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
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G |
Cldn15 |
claudin 15 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CLDN15 mRNA; Lithium Chloride results in decreased expression of CLDN15 protein |
CTD |
PMID:33901603 |
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NCBI chr12:19,698,169...19,708,419
Ensembl chr12:19,698,337...19,706,819
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G |
Col13a1 |
collagen type XIII alpha 1 chain |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of COL13A1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032
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G |
Col1a2 |
collagen type I alpha 2 chain |
affects expression |
ISO |
Lithium Chloride affects the expression of COL1A2 mRNA |
CTD |
PMID:24704097 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases expression increases phosphorylation |
EXP ISO |
Lithium Chloride results in increased expression of CREB1 mRNA Lithium Chloride results in increased phosphorylation of CREB1 protein |
CTD |
PMID:18830594 PMID:19285016 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crisp2 |
cysteine-rich secretory protein 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of CRISP2 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 9:20,107,649...20,131,967
Ensembl chr 9:20,107,701...20,131,959
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G |
Ctcf |
CCCTC-binding factor |
increases expression |
EXP |
Lithium Chloride results in increased expression of CTCF mRNA |
CTD |
PMID:19285016 |
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NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions decreases phosphorylation increases activity increases localization increases expression increases stability affects localization |
ISO EXP |
[Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; Hexachlorophene inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Aspirin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [celastrol results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Indomethacin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of and results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Lithium Chloride results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased localization of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased localization of and results in increased activity of CTNNB1 protein; MALAT1 protein affects the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein] Lithium Chloride results in decreased phosphorylation of CTNNB1 protein [[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride results in increased expression of and affects the localization of CTNNB1 protein Lithium Chloride results in increased localization of CTNNB1 protein [[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein] Lithium Chloride results in increased expression of CTNNB1 mRNA; Lithium Chloride results in increased expression of CTNNB1 protein Lithium Chloride results in increased stability of CTNNB1 protein Lithium Chloride affects the localization of CTNNB1 protein; Lithium Chloride affects the localization of CTNNB1 protein modified form |
CTD |
PMID:12813129 PMID:15364539 PMID:16053526 PMID:16076840 PMID:16735606 PMID:18972237 PMID:19228266 PMID:19274078 PMID:19442631 PMID:19582394 PMID:19679347 PMID:20069066 PMID:20074550 PMID:20118494 PMID:20694829 PMID:20696143 PMID:22134133 PMID:22493441 PMID:22935447 PMID:23326414 PMID:23872260 PMID:24244343 PMID:24464479 PMID:24534281 PMID:26990689 PMID:27018151 PMID:27045591 PMID:27226553 PMID:28343033 PMID:28886972 PMID:28901456 PMID:30171970 PMID:30377735 PMID:31715269 PMID:32112862 More...
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of CYP1A1 mRNA |
CTD |
PMID:21498875 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
EXP |
Lithium Chloride promotes the reaction [Cadmium results in increased expression of DDIT3 protein] |
CTD |
PMID:27658547 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Diras3 |
DIRAS family GTPase 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of DIRAS3 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 6:130,524,972...130,527,690
Ensembl chr 6:130,524,742...130,530,825
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G |
Dvl2 |
dishevelled segment polarity protein 2 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of DVL2 protein] |
CTD |
PMID:30171970 |
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NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
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G |
Ebf1 |
EBF transcription factor 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of EBF1 mRNA |
CTD |
PMID:27226553 |
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NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
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G |
Efna3 |
ephrin A3 |
decreases expression |
EXP |
Lithium Chloride results in decreased expression of EFNA3 mRNA |
CTD |
PMID:18772502 |
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NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases expression |
ISO |
[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA] Lithium Chloride results in increased expression of EGFR mRNA; Lithium Chloride results in increased expression of EGFR protein |
CTD |
PMID:22493441 |
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NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Enox2 |
ecto-NOX disulfide-thiol exchanger 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ENOX2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr X:128,270,941...128,593,074
Ensembl chr X:128,271,074...128,593,039
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G |
Epha5 |
EPH receptor A5 |
decreases expression |
EXP |
Lithium Chloride results in decreased expression of EPHA5 mRNA; Lithium Chloride results in decreased expression of EPHA5 protein |
CTD |
PMID:18772502 |
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NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]]; Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] |
CTD |
PMID:33396024 |
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ERBB3 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
increases expression |
ISO |
Lithium Chloride results in increased expression of ERCC1 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
[Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; Lithium Chloride inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Lithium Chloride inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein]; Lithium Chloride results in decreased phosphorylation of and results in decreased stability of and results in decreased expression of ESR1 protein |
CTD |
PMID:16076840 PMID:26990689 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esrrg |
estrogen-related receptor gamma |
increases expression |
ISO |
Lithium Chloride results in increased expression of ESRRG mRNA |
CTD |
PMID:23527032 |
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NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions decreases expression |
ISO |
Lithium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA] Lithium Chloride results in decreased expression of F3 mRNA |
CTD |
PMID:15371228 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
F5 |
coagulation factor V |
increases expression |
ISO |
Lithium Chloride results in increased expression of F5 mRNA |
CTD |
PMID:23527032 |
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NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
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G |
Fam104b |
family with sequence similarity 104 member B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of FAM104B mRNA |
CTD |
PMID:23527032 |
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NCBI chr X:19,310,182...19,393,163 NCBI chr X:19,338,236...19,340,924
Ensembl chr X:19,349,560...19,378,486
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G |
Fam90a1 |
family with sequence similarity 90, member A1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of FAM90A1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr16:70,098,439...70,106,147
Ensembl chr16:70,098,740...70,101,241
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G |
Fbxo32 |
F-box protein 32 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of FBXO32 mRNA |
CTD |
PMID:21832246 |
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NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
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G |
Fbxw7 |
F-box and WD repeat domain containing 7 |
multiple interactions |
ISO |
FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein] |
CTD |
PMID:25897075 |
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NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
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G |
Fmn2 |
formin 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of FMN2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
Butyrates promotes the reaction [Lithium Chloride results in increased expression of FOS protein] |
CTD |
PMID:20346924 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fxyd5 |
FXYD domain-containing ion transport regulator 5 |
increases expression |
ISO |
Lithium Chloride results in increased expression of FXYD5 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
EXP |
Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein]; Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] |
CTD |
PMID:30926361 PMID:32763437 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
Fzd3 |
frizzled class receptor 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of FZD3 mRNA |
CTD |
PMID:20069066 |
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NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
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G |
Fzd4 |
frizzled class receptor 4 |
increases expression |
ISO |
Lithium Chloride results in increased expression of FZD4 mRNA |
CTD |
PMID:20069066 |
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NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
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G |
Fzd6 |
frizzled class receptor 6 |
increases expression |
ISO |
Lithium Chloride results in increased expression of FZD6 mRNA |
CTD |
PMID:20069066 |
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NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions |
ISO |
GATA1 protein results in decreased susceptibility to [Lithium Chloride co-treated with Tretinoin] |
CTD |
PMID:19230972 |
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NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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G |
Gbgt1 |
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) |
increases expression |
ISO |
Lithium Chloride results in increased expression of GBGT1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:11,826,131...11,829,745
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G |
Gcg |
glucagon |
multiple interactions increases expression |
ISO |
Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter] Lithium Chloride results in increased expression of GCG mRNA |
CTD |
PMID:19582394 |
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NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
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G |
Gda |
guanine deaminase |
increases expression |
ISO |
Lithium Chloride results in increased expression of GDA mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions |
ISO EXP |
Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein] [Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP protein; Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein] |
CTD |
PMID:23872260 PMID:31018114 |
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NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Gip |
gastric inhibitory polypeptide |
multiple interactions increases expression |
ISO |
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter] Lithium Chloride results in increased expression of GIP mRNA |
CTD |
PMID:19582394 |
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NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503
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G |
Gja1 |
gap junction protein, alpha 1 |
affects localization multiple interactions increases expression |
EXP |
Lithium Chloride affects the localization of GJA1 protein [[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein Lithium Chloride results in increased expression of GJA1 protein |
CTD |
PMID:18972237 PMID:21177194 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Glb1 |
galactosidase, beta 1 |
increases activity |
ISO |
Lithium Chloride results in increased activity of GLB1 protein |
CTD |
PMID:34624459 |
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NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in decreased expression of GLUD1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in decreased expression of GLUD2 mRNA] |
CTD |
PMID:32494933 |
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NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
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G |
Gnaz |
G protein subunit alpha z |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of GNAZ mRNA |
CTD |
PMID:23527032 |
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NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
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G |
Gnpat |
glyceronephosphate O-acyltransferase |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of GNPAT mRNA |
CTD |
PMID:23527032 |
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NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
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G |
Gramd2a |
GRAM domain containing 2A |
increases expression |
ISO |
Lithium Chloride results in increased expression of GRAMD2A mRNA |
CTD |
PMID:23527032 |
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NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842
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G |
Gramd2b |
GRAM domain containing 2B |
increases expression |
ISO |
Lithium Chloride results in increased expression of GRAMD2B mRNA |
CTD |
PMID:23527032 |
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NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953
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G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
multiple interactions decreases expression |
ISO |
[[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists; [Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA Lithium Chloride results in decreased expression of GRIN1 mRNA |
CTD |
PMID:19285052 PMID:34748853 |
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NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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G |
Grm1 |
glutamate metabotropic receptor 1 |
multiple interactions |
EXP |
[Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of GRM1 mRNA |
CTD |
PMID:32494933 |
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NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
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G |
Grn |
granulin precursor |
increases expression |
ISO |
Lithium Chloride results in increased expression of GRN mRNA |
CTD |
PMID:23527032 |
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NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
multiple interactions |
EXP |
Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3A protein] |
CTD |
PMID:27658547 |
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NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation affects phosphorylation increases stability decreases expression decreases activity increases phosphorylation increases expression |
ISO EXP |
[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in decreased expression of GSK3B protein modified form]; Lithium Chloride inhibits the reaction [celastrol results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [quinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein]; Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in decreased expression of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of and results in decreased activity of GSK3B protein; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein; PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] Lithium Chloride results in decreased phosphorylation of GSK3B protein Lithium Chloride affects the phosphorylation of GSK3B protein Lithium Chloride results in increased stability of GSK3B protein [[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride co-treated with Cisplatin] results in increased phosphorylation of GSK3B protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; calyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Lithium Chloride inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein Lithium Chloride results in decreased expression of GSK3B mRNA Lithium Chloride results in increased expression of GSK3B protein modified form [[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cisplatin results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein |
CTD |
PMID:12813129 PMID:15247282 PMID:15364539 PMID:15585669 PMID:15753396 PMID:17868649 PMID:18830594 PMID:18932008 PMID:18972237 PMID:19101580 PMID:19196980 PMID:19274078 PMID:19440036 PMID:19442631 PMID:19448134 PMID:19582394 PMID:19679347 PMID:19823589 PMID:20090934 PMID:20093106 PMID:20694829 PMID:20696143 PMID:20807582 PMID:20937724 PMID:21278055 PMID:21296133 PMID:21364661 PMID:21498875 PMID:22493441 PMID:22944069 PMID:23651617 PMID:24464479 PMID:26459185 PMID:26990689 PMID:27018151 PMID:27050422 PMID:27658547 PMID:28343033 PMID:28759639 PMID:28886972 PMID:30171970 PMID:30703377 PMID:30926361 PMID:31220555 PMID:31715269 PMID:32112862 More...
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
multiple interactions |
ISO |
[Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA |
CTD |
PMID:20118494 |
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NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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G |
H1f2 |
H1.2 linker histone, cluster member |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of H1-2 mRNA |
CTD |
PMID:15711924 |
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NCBI chr17:41,391,106...41,392,611
Ensembl chr17:41,388,477...41,392,635
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of HAPLN1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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G |
Hdac1 |
histone deacetylase 1 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter] |
CTD |
PMID:19582394 |
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NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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G |
Hdac7 |
histone deacetylase 7 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of HDAC7 mRNA |
CTD |
PMID:26272751 |
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NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072
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G |
Hdgfl3 |
HDGF like 3 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of HDGFL3 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
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G |
Hes7 |
hes family bHLH transcription factor 7 |
increases expression |
ISO |
Lithium Chloride results in increased expression of HES7 mRNA |
CTD |
PMID:23326414 |
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NCBI chr10:53,824,124...53,828,350
Ensembl chr10:53,825,574...53,828,097
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G |
Hist2h4a |
histone cluster 2 H4 family member A |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of H4C4 mRNA |
CTD |
PMID:15711924 |
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 protein] |
CTD |
PMID:32494933 |
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NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
Lithium Chloride results in increased expression of HMOX1 mRNA Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; Lithium Chloride promotes the reaction [Cadmium results in increased expression of HMOX1 protein] [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of HMOX1 mRNA; Lithium Chloride promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein] |
CTD |
PMID:23527032 PMID:26074776 PMID:27658547 PMID:30672058 PMID:33645131 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of HSPA12A mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO |
[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form |
CTD |
PMID:20090934 |
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of HTR2A mRNA |
CTD |
PMID:23527032 |
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NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Ibsp |
integrin-binding sialoprotein |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of IBSP mRNA |
CTD |
PMID:19442631 |
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NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ICAM1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id3 |
inhibitor of DNA binding 3, HLH protein |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ID3 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
multiple interactions |
ISO |
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein] |
CTD |
PMID:31760073 |
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NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
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G |
Ids |
iduronate 2-sulfatase |
increases expression |
ISO |
Lithium Chloride results in increased expression of IDS mRNA |
CTD |
PMID:23527032 |
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NCBI chr X:149,025,977...149,046,639
Ensembl chr X:149,025,976...149,046,663
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G |
Ifng |
interferon gamma |
increases expression |
ISO |
Lithium Chloride results in increased expression of IFNG mRNA |
CTD |
PMID:9328138 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA] |
CTD |
PMID:19657059 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igll1 |
immunoglobulin lambda-like polypeptide 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of IGLL1 mRNA |
CTD |
PMID:27226553 |
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NCBI chr11:84,138,847...84,142,238
Ensembl chr11:84,138,910...84,142,216
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G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
EXP ISO |
Lithium Chloride results in increased expression of IL1B protein [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B protein Lithium Chloride results in increased expression of IL1B mRNA |
CTD |
PMID:19010416 PMID:31018114 PMID:33901603 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of IL2 mRNA |
CTD |
PMID:9328138 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO EXP |
Lithium Chloride results in increased expression of IL6 mRNA [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 protein |
CTD |
PMID:9328138 PMID:31018114 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ilrun |
inflammation and lipid regulator with UBA-like and NBR1-like domains |
increases expression |
ISO |
Lithium Chloride results in increased expression of ILRUN mRNA |
CTD |
PMID:23527032 |
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NCBI chr20:5,809,931...5,876,231
Ensembl chr20:5,809,936...5,876,012
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G |
Iqca1 |
IQ motif containing with AAA domain 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of IQCA mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 9:90,626,735...90,742,563
Ensembl chr 9:90,626,744...90,742,618
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G |
Itgam |
integrin subunit alpha M |
multiple interactions |
ISO |
Lithium Chloride promotes the reaction [Tretinoin results in increased expression of ITGAM protein] |
CTD |
PMID:29743969 |
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NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgb8 |
integrin subunit beta 8 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ITGB8 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476
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G |
Jdp2 |
Jun dimerization protein 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of JDP2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of JUN mRNA |
CTD |
PMID:26272751 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kbtbd11 |
kelch repeat and BTB domain containing 11 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of KBTBD11 mRNA |
CTD |
PMID:23527032 |
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NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736
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G |
Kcnk6 |
potassium two pore domain channel subfamily K member 6 |
increases expression |
ISO |
Lithium Chloride results in increased expression of KCNK6 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677
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G |
Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
increases expression |
ISO |
Lithium Chloride results in increased expression of KCNN4 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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G |
Kdr |
kinase insert domain receptor |
increases expression |
ISO |
Lithium Chloride results in increased expression of KDR mRNA |
CTD |
PMID:26272751 |
|
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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G |
Kif5a |
kinesin family member 5A |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of KIF5A mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
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G |
Krt19 |
keratin 19 |
increases expression |
ISO |
Lithium Chloride results in increased expression of KRT19 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
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G |
Krt34 |
keratin 34 |
increases expression |
ISO |
Lithium Chloride results in increased expression of KRT34 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr10:84,970,351...84,974,040
Ensembl chr10:84,970,017...84,974,040
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G |
Lamc1 |
laminin subunit gamma 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of LAMC1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of LCP1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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G |
Lef1 |
lymphoid enhancer binding factor 1 |
multiple interactions |
ISO |
Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter] |
CTD |
PMID:19582394 |
|
NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
increases expression |
ISO |
Lithium Chloride results in increased expression of LGR5 mRNA |
CTD |
PMID:33901603 |
|
NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
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G |
Lig4 |
DNA ligase 4 |
increases expression |
EXP |
Lithium Chloride results in increased expression of LIG4 mRNA; Lithium Chloride results in increased expression of LIG4 protein |
CTD |
PMID:19285016 |
|
NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
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G |
Lrp6 |
LDL receptor related protein 6 |
increases expression |
ISO |
Lithium Chloride results in increased expression of LRP6 mRNA |
CTD |
PMID:20069066 |
|
NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
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G |
Maged2 |
MAGE family member D2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MAGED2 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr X:19,733,593...19,741,769
Ensembl chr X:19,733,597...19,740,477
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G |
Mapk1 |
mitogen activated protein kinase 1 |
affects phosphorylation |
EXP |
Lithium Chloride affects the phosphorylation of MAPK1 protein |
CTD |
PMID:21364661 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk10 |
mitogen activated protein kinase 10 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MAPK10 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
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G |
Mapk3 |
mitogen activated protein kinase 3 |
affects phosphorylation |
EXP |
Lithium Chloride affects the phosphorylation of MAPK3 protein |
CTD |
PMID:21364661 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapt |
microtubule-associated protein tau |
multiple interactions decreases expression |
EXP ISO |
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein] Lithium Chloride results in decreased expression of MAPT mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein] |
CTD |
PMID:20937724 PMID:23527032 PMID:27050422 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Marveld2 |
MARVEL domain containing 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MARVELD2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
increases expression |
ISO |
Lithium Chloride results in increased expression of MCL1 mRNA; Lithium Chloride results in increased expression of MCL1 protein |
CTD |
PMID:22493441 |
|
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mcm2 |
minichromosome maintenance complex component 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MCM2 mRNA |
CTD |
PMID:17440966 |
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NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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G |
Mcm4 |
minichromosome maintenance complex component 4 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MCM4 mRNA |
CTD |
PMID:17440966 |
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NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
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G |
Mcm5 |
minichromosome maintenance complex component 5 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MCM5 mRNA |
CTD |
PMID:17440966 |
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NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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G |
Mcm6 |
minichromosome maintenance complex component 6 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MCM6 mRNA |
CTD |
PMID:17440966 |
|
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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G |
Mcm7 |
minichromosome maintenance complex component 7 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MCM7 mRNA |
CTD |
PMID:17440966 |
|
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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G |
Mesp1 |
mesoderm posterior bHLH transcription factor 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MESP1 mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
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G |
Mex3b |
mex-3 RNA binding family member B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MEX3B mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
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G |
Mib1 |
MIB E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MIB1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
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G |
Mir152 |
microRNA 152 |
increases expression |
EXP |
Lithium Chloride results in increased expression of MIR152 mRNA |
CTD |
PMID:19254429 |
|
NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
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G |
Mir155 |
microRNA 155 |
increases expression |
EXP |
Lithium Chloride results in increased expression of MIR155 mRNA |
CTD |
PMID:19254429 |
|
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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G |
Mir200c |
microRNA 200c |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of MIR200C mRNA |
CTD |
PMID:31018114 |
|
NCBI chr 4:157,523,679...157,523,747
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G |
Mir221 |
microRNA 221 |
increases expression |
EXP |
Lithium Chloride results in increased expression of MIR221 mRNA |
CTD |
PMID:19254429 |
|
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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G |
Mir34a |
microRNA 34a |
multiple interactions |
ISO |
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of MIR34A mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of MIR34A mRNA |
CTD |
PMID:26074776 |
|
NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
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G |
Mir494 |
microRNA 494 |
decreases expression |
EXP |
Lithium Chloride results in decreased expression of MIR494 mRNA |
CTD |
PMID:19254429 |
|
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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G |
Mitf |
melanocyte inducing transcription factor |
increases expression |
ISO |
Lithium Chloride results in increased expression of MITF mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
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G |
Mixl1 |
Mix paired-like homeobox 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MIXL1 mRNA |
CTD |
PMID:26272751 |
|
NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
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G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of MKI67 protein]] |
CTD |
PMID:15845746 |
|
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mllt11 |
MLLT11, transcription factor 7 cofactor |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MLLT11 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
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G |
Mmab |
metabolism of cobalamin associated B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MMAB mRNA |
CTD |
PMID:23527032 |
|
NCBI chr12:42,159,109...42,172,496
Ensembl chr12:42,159,089...42,172,490
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G |
Mmp7 |
matrix metallopeptidase 7 |
multiple interactions increases expression |
ISO |
MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MMP7 protein]; MALAT1 protein affects the reaction [resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein]]; resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein] |
CTD |
PMID:24244343 |
|
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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G |
Mpz |
myelin protein zero |
multiple interactions increases expression |
ISO |
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ protein] Lithium Chloride results in increased expression of MPZ mRNA; Lithium Chloride results in increased expression of MPZ protein |
CTD |
PMID:27788593 |
|
NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
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G |
Mrpl47 |
mitochondrial ribosomal protein L47 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of MRPL47 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 2:115,507,842...115,520,093
Ensembl chr 2:115,500,264...115,518,994
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G |
Msgn1 |
mesogenin 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MSGN1 mRNA |
CTD |
PMID:23326414 |
|
NCBI chr 6:33,912,787...33,913,427
Ensembl chr 6:33,912,787...33,913,427
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G |
Msi1 |
musashi RNA-binding protein 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MSI1 protein |
CTD |
PMID:20069066 |
|
NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
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G |
Mt1-ps3 |
metallothionein 1, pseudogene 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MT1G mRNA |
CTD |
PMID:23527032 |
|
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions decreases expression |
ISO |
Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein] Lithium Chloride results in decreased expression of MTOR mRNA |
CTD |
PMID:30171970 PMID:34748853 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
EXP ISO |
Lithium Chloride inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein] Lithium Chloride results in increased expression of MYC mRNA; Lithium Chloride results in increased expression of MYC protein Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]] |
CTD |
PMID:19679347 PMID:22100782 PMID:22493441 PMID:24244343 PMID:26272751 PMID:27018151 PMID:28901456 PMID:33901603 More...
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myct1 |
myc target 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MYCT1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410
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G |
Myh8 |
myosin heavy chain 8 |
increases expression |
ISO |
Lithium Chloride results in increased expression of MYH8 mRNA |
CTD |
PMID:20694829 |
|
NCBI chr10:51,963,510...51,993,103
Ensembl chr10:51,963,510...51,993,232
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G |
Myo1e |
myosin IE |
increases expression |
ISO |
Lithium Chloride results in increased expression of MYO1E mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
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G |
Nanog |
Nanog homeobox |
increases expression multiple interactions |
ISO |
Lithium Chloride results in increased expression of NANOG mRNA SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA] |
CTD |
PMID:20069066 |
|
NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
increases expression |
EXP |
Lithium Chloride results in increased expression of NEDD4 protein |
CTD |
PMID:21734099 |
|
NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nes |
nestin |
increases expression |
ISO |
Lithium Chloride results in increased expression of NES mRNA |
CTD |
PMID:26272751 |
|
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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G |
Neurod1 |
neuronal differentiation 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of NEUROD1 mRNA |
CTD |
PMID:33901603 |
|
NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
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G |
Nfatc3 |
nuclear factor of activated T-cells 3 |
increases activity |
ISO |
Lithium Chloride results in increased activity of NFATC3 protein |
CTD |
PMID:20694829 |
|
NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP ISO |
Lithium Chloride affects the reaction [triptolide affects the expression of NFE2L2 protein]; Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein] [Lithium Chloride results in increased abundance of Lithium] which affects the localization of NFE2L2 protein; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NFE2L2 mRNA |
CTD |
PMID:26074776 PMID:30926361 PMID:32763437 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
increases degradation |
ISO |
Lithium Chloride results in increased degradation of NFKBIA protein |
CTD |
PMID:24085292 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nhlh1 |
nescient helix loop helix 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of NHLH1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr13:84,517,347...84,522,548
Ensembl chr13:84,517,289...84,525,094
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G |
Nkd1 |
NKD inhibitor of WNT signaling pathway 1 |
increases expression multiple interactions |
ISO |
Lithium Chloride results in increased expression of NKD1 mRNA Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA] |
CTD |
PMID:24534281 |
|
NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
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G |
Nos1 |
nitric oxide synthase 1 |
increases expression |
EXP |
Lithium Chloride results in increased expression of NOS1 mRNA |
CTD |
PMID:9500967 |
|
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of NOS2 mRNA |
CTD |
PMID:19679347 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Notch1 |
notch receptor 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of NOTCH1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Npepl1 |
aminopeptidase-like 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of NPEPL1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:162,893,891...162,906,492
Ensembl chr 3:162,893,943...162,906,492
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO EXP |
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NQO1 mRNA Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NQO1 protein]] |
CTD |
PMID:26074776 PMID:33645131 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 protein] |
CTD |
PMID:32494933 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
multiple interactions increases expression |
EXP |
CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of NR4A2 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein] Lithium Chloride results in increased expression of NR4A2 mRNA; Lithium Chloride results in increased expression of NR4A2 protein |
CTD |
PMID:27045591 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nrcam |
neuronal cell adhesion molecule |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of NRCAM mRNA |
CTD |
PMID:26272751 |
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NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
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G |
Nsd2 |
nuclear receptor binding SET domain protein 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of NSD2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr14:76,833,194...76,911,304
Ensembl chr14:76,835,637...76,913,641
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G |
Ntn1 |
netrin 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of NTN1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
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G |
Ocln |
occludin |
decreases expression increases expression |
ISO |
Lithium Chloride results in decreased expression of OCLN mRNA Lithium Chloride results in increased expression of OCLN protein |
CTD |
PMID:33901603 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Oprm1 |
opioid receptor, mu 1 |
decreases expression |
EXP |
Lithium Chloride results in decreased expression of OPRM1 protein |
CTD |
PMID:17919468 |
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NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
EXP ISO |
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; [Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein] Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form] |
CTD |
PMID:27658547 PMID:28343033 PMID:28886972 PMID:30377735 PMID:31396050 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pax3 |
paired box 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PAX3 protein |
CTD |
PMID:19101580 |
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NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions decreases expression |
EXP |
Lithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]; Lithium Chloride inhibits the reaction [Dexamethasone results in increased expression of PCK1 mRNA] Lithium Chloride results in decreased expression of PCK1 mRNA |
CTD |
PMID:1371108 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of PCNA protein]] Lithium Chloride results in increased expression of PCNA protein |
CTD |
PMID:15845746 PMID:27018151 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pde4b |
phosphodiesterase 4B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PDE4B mRNA |
CTD |
PMID:23527032 |
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NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
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G |
Pdgfrl |
platelet-derived growth factor receptor-like |
increases expression |
ISO |
Lithium Chloride results in increased expression of PDGFRL mRNA |
CTD |
PMID:23527032 |
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NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
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G |
Pdia5 |
protein disulfide isomerase family A, member 5 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PDIA5 mRNA |
CTD |
PMID:23527032 |
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NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
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G |
Pdlim5 |
PDZ and LIM domain 5 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PDLIM5 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
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G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
multiple interactions |
EXP |
[Pilocarpine co-treated with Lithium Chloride co-treated with 3-chloroacetylindole] results in decreased phosphorylation of PEA15 protein; [Pilocarpine co-treated with Lithium Chloride] results in decreased phosphorylation of PEA15 protein |
CTD |
PMID:31396050 |
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NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
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G |
Pigr |
polymeric immunoglobulin receptor |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PIGR mRNA |
CTD |
PMID:33901603 |
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NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
multiple interactions affects response to substance increases response to substance |
ISO |
PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] PIK3CA protein affects the susceptibility to Lithium Chloride PIK3CA protein mutant form results in increased susceptibility to Lithium Chloride |
CTD |
PMID:19196980 |
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NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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G |
Pitpnb |
phosphatidylinositol transfer protein, beta |
increases expression |
ISO |
Lithium Chloride results in increased expression of PITPNB mRNA |
CTD |
PMID:15711924 |
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NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314
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G |
Plagl1 |
PLAG1 like zinc finger 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PLAGL1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
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G |
Plau |
plasminogen activator, urokinase |
decreases expression increases expression |
ISO |
Lithium Chloride results in decreased expression of PLAU mRNA Lithium Chloride results in increased expression of PLAU mRNA |
CTD |
PMID:15711924 PMID:23527032 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Pld1 |
phospholipase D1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PLD1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
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G |
Plekha6 |
pleckstrin homology domain containing A6 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PLEKHA6 mRNA |
CTD |
PMID:23527032 |
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NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
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G |
Plin1 |
perilipin 1 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of PLIN1 mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of PLIN1 mRNA] |
CTD |
PMID:28291828 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plpp2 |
phospholipid phosphatase 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PLPP2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PMAIP1 mRNA; Lithium Chloride results in increased expression of PMAIP1 protein |
CTD |
PMID:15711924 |
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NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
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G |
Pmel |
premelanosome protein |
increases expression |
ISO |
Lithium Chloride results in increased expression of PMEL mRNA |
CTD |
PMID:23527032 |
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NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions increases expression |
ISO |
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 protein] Lithium Chloride results in increased expression of PMP22 mRNA; Lithium Chloride results in increased expression of PMP22 protein |
CTD |
PMID:27788593 |
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NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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G |
Polr3b |
RNA polymerase III subunit B |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of POLR3B mRNA |
CTD |
PMID:23527032 |
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NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598
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G |
Popdc3 |
popeye domain containing 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of POPDC3 mRNA |
CTD |
PMID:15711924 |
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NCBI chr20:48,772,382...48,800,364
Ensembl chr20:48,772,462...48,800,593
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G |
Pou5f1 |
POU class 5 homeobox 1 |
multiple interactions increases expression |
ISO |
CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA] Lithium Chloride results in increased expression of POU5F1 mRNA; Lithium Chloride results in increased expression of POU5F1 protein |
CTD |
PMID:20069066 PMID:20074550 |
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NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
ISO |
Lithium Chloride results in increased expression of PPARG mRNA |
CTD |
PMID:23527032 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppm1h |
protein phosphatase, Mg2+/Mn2+ dependent, 1H |
increases expression |
ISO |
Lithium Chloride results in increased expression of PPM1H mRNA |
CTD |
PMID:23527032 |
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NCBI chr 7:58,338,661...58,599,547
Ensembl chr 7:58,338,661...58,599,547
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G |
Ppp1r14c |
protein phosphatase 1, regulatory (inhibitor) subunit 14c |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PPP1R14C mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:39,773,403...39,886,970
Ensembl chr 1:39,773,403...39,886,956
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G |
Ppp3r1 |
protein phosphatase 3, regulatory subunit B, alpha |
increases expression |
ISO |
Lithium Chloride results in increased expression of PPP3R1 mRNA |
CTD |
PMID:15711924 |
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NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907
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G |
Prr16 |
proline rich 16 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PRR16 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329
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G |
Psme1 |
proteasome activator subunit 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of PSME1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
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G |
Ptges |
prostaglandin E synthase |
increases expression multiple interactions |
ISO |
Lithium Chloride results in increased expression of PTGES protein [Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein] |
CTD |
PMID:19692487 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO EXP |
Lithium Chloride results in increased expression of PTGS2 mRNA; Lithium Chloride results in increased expression of PTGS2 protein |
CTD |
PMID:9500967 PMID:15585669 PMID:15711924 PMID:19797860 PMID:24085292 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ptx3 |
pentraxin 3 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PTX3 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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G |
Purg |
purine-rich element binding protein G |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of PURG mRNA |
CTD |
PMID:23527032 |
|
NCBI chr16:58,732,327...58,763,356
Ensembl chr16:58,720,335...58,763,359
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G |
Pxn |
paxillin |
increases expression |
ISO |
Lithium Chloride results in increased expression of PXN mRNA |
CTD |
PMID:23527032 |
|
NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
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G |
Pycard |
PYD and CARD domain containing |
increases expression |
ISO |
Lithium Chloride results in increased expression of PYCARD mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Rab23 |
RAB23, member RAS oncogene family |
increases expression |
ISO |
Lithium Chloride results in increased expression of RAB23 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
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G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]] Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein] |
CTD |
PMID:15845746 PMID:22820424 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Rcan1 |
regulator of calcineurin 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of RCAN1 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
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G |
Reck |
reversion-inducing-cysteine-rich protein with kazal motifs |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK mRNA; [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK protein |
CTD |
PMID:31018114 |
|
NCBI chr 5:58,102,915...58,169,513
Ensembl chr 5:58,102,981...58,169,502
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation decreases phosphorylation |
EXP ISO |
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; [Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein] Lithium Chloride results in increased phosphorylation of RELA protein Lithium Chloride results in decreased phosphorylation of RELA protein |
CTD |
PMID:24085292 PMID:31396050 PMID:33901603 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Rexo2 |
RNA exonuclease 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of REXO2 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622
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G |
Rgs4 |
regulator of G-protein signaling 4 |
increases expression |
ISO |
Lithium Chloride results in increased expression of RGS4 mRNA; Lithium Chloride results in increased expression of RGS4 protein |
CTD |
PMID:15711924 |
|
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
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G |
Rictor |
RPTOR independent companion of MTOR, complex 2 |
multiple interactions |
ISO |
FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein]; Lithium Chloride results in increased expression of and results in decreased ubiquitination of RICTOR protein |
CTD |
PMID:25897075 |
|
NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
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G |
Rnd3 |
Rho family GTPase 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of RND3 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
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G |
Rnf144b |
ring finger protein 144B |
multiple interactions increases degradation |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein]; Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein] |
CTD |
PMID:29724995 |
|
NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760
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G |
Rnf40 |
ring finger protein 40 |
increases expression |
EXP |
Lithium Chloride results in increased expression of RNF40 protein |
CTD |
PMID:21734099 |
|
NCBI chr 1:182,202,475...182,217,899
Ensembl chr 1:182,202,600...182,217,241
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G |
Rrad |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
increases expression |
ISO |
Lithium Chloride results in increased expression of RRAD mRNA |
CTD |
PMID:15711924 |
|
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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G |
Rtn1 |
reticulon 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of RTN1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
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G |
S100a3 |
S100 calcium binding protein A3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of S100A3 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 2:176,034,283...176,089,702
Ensembl chr 2:176,049,520...176,089,702
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G |
Scn5a |
sodium voltage-gated channel alpha subunit 5 |
decreases activity |
ISO |
Lithium Chloride results in decreased activity of SCN5A protein |
CTD |
PMID:16144991 |
|
NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
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G |
Scnn1a |
sodium channel epithelial 1 subunit alpha |
increases expression |
ISO |
Lithium Chloride results in increased expression of SCNN1A mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
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G |
Scpep1 |
serine carboxypeptidase 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of SCPEP1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression multiple interactions |
ISO |
Lithium Chloride results in decreased expression of SFRP2 mRNA SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA] |
CTD |
PMID:20069066 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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G |
Shank2 |
SH3 and multiple ankyrin repeat domains 2 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of SHANK2 mRNA |
CTD |
PMID:34748853 |
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NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
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G |
Shf |
Src homology 2 domain containing F |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of SHF mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:109,296,517...109,316,315
Ensembl chr 3:109,296,784...109,316,328
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G |
Shh |
sonic hedgehog signaling molecule |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of SHH mRNA |
CTD |
PMID:26272751 |
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NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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G |
Shpk |
sedoheptulokinase |
increases expression |
ISO |
Lithium Chloride results in increased expression of SHPK mRNA |
CTD |
PMID:23527032 |
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NCBI chr10:57,817,551...57,841,981
Ensembl chr10:57,817,629...57,841,980
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G |
Six1 |
SIX homeobox 1 |
increases expression increases response to substance |
ISO |
Lithium Chloride results in increased expression of SIX1 mRNA; Lithium Chloride results in increased expression of SIX1 protein SIX1 protein results in increased susceptibility to Lithium Chloride |
CTD |
PMID:19101580 |
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NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
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G |
Slc12a1 |
solute carrier family 12 member 1 |
decreases expression multiple interactions |
ISO |
Lithium Chloride results in decreased expression of SLC12A1 protein PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein] |
CTD |
PMID:19692487 |
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NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
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G |
Slc20a1 |
solute carrier family 20 member 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of SLC20A1 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
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G |
Slc3a2 |
solute carrier family 3 member 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of SLC3A2 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc5a3 |
solute carrier family 5 member 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of SLC5A3 mRNA |
CTD |
PMID:15711924 |
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NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
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G |
Slc6a4 |
solute carrier family 6 member 4 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of SLC6A4 mRNA |
CTD |
PMID:34748853 |
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NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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G |
Snai1 |
snail family transcriptional repressor 1 |
decreases degradation multiple interactions |
ISO |
Lithium Chloride results in decreased degradation of SNAI1 protein [Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein |
CTD |
PMID:19440036 PMID:20348013 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snca |
synuclein alpha |
increases expression |
ISO |
Lithium Chloride results in increased expression of SNCA mRNA |
CTD |
PMID:23527032 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in decreased activity of SOD2 protein] |
CTD |
PMID:31760073 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Spag5 |
sperm associated antigen 5 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of SPAG5 mRNA |
CTD |
PMID:23527032 |
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NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
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G |
Sqor |
sulfide quinone oxidoreductase |
increases expression |
ISO |
Lithium Chloride results in increased expression of SQOR mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO |
Lithium Chloride promotes the reaction [Cisplatin results in decreased expression of SQSTM1 protein] |
CTD |
PMID:31220555 |
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NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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G |
Stard7 |
StAR-related lipid transfer domain containing 7 |
multiple interactions |
ISO |
[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein |
CTD |
PMID:19679347 |
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NCBI chr 3:114,487,163...114,515,825
Ensembl chr 3:114,485,600...114,515,813
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] |
CTD |
PMID:22493441 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Stat6 |
signal transducer and activator of transcription 6 |
increases expression |
ISO |
Lithium Chloride results in increased expression of STAT6 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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G |
Tars1 |
threonyl-tRNA synthetase 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TARS1 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 2:60,368,251...60,387,733
Ensembl chr 2:60,367,796...60,387,717
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G |
Tbc1d8 |
TBC1 domain family, member 8 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of TBC1D8 mRNA |
CTD |
PMID:15711924 |
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NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409
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G |
Tcf4 |
transcription factor 4 |
multiple interactions |
ISO |
Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]] |
CTD |
PMID:22935447 |
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NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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G |
Tcf7l2 |
transcription factor 7 like 2 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter] |
CTD |
PMID:19582394 |
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NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
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G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TGFBR2 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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G |
Tjp1 |
tight junction protein 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of TJP1 mRNA |
CTD |
PMID:33901603 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
EXP |
[Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of TLR4 mRNA] |
CTD |
PMID:32494933 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tm4sf1 |
transmembrane 4 L six family member 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TM4SF1 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
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G |
Tnc |
tenascin C |
increases expression |
ISO |
Lithium Chloride results in increased expression of TNC mRNA |
CTD |
PMID:15711924 |
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NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions |
EXP ISO |
Lithium Chloride results in increased expression of TNF protein [Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF protein; Rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of TNF protein] Lithium Chloride results in increased expression of TNF mRNA |
CTD |
PMID:18455351 PMID:31018114 PMID:33901603 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnnc1 |
troponin C1, slow skeletal and cardiac type |
increases expression |
ISO |
Lithium Chloride results in increased expression of TNNC1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr16:6,400,801...6,405,419
Ensembl chr16:6,402,171...6,405,634
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G |
Tnnt1 |
troponin T1, slow skeletal type |
increases expression |
ISO |
Lithium Chloride results in increased expression of TNNT1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
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G |
Top3a |
DNA topoisomerase III alpha |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of TOP3A mRNA |
CTD |
PMID:23527032 |
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NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559
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G |
Tp53 |
tumor protein p53 |
increases expression multiple interactions |
ISO |
Lithium Chloride results in increased expression of TP53 protein Lithium Chloride results in decreased degradation of and results in increased expression of TRP53 protein |
CTD |
PMID:16055726 PMID:17210701 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tp63 |
tumor protein p63 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TP63 mRNA |
CTD |
PMID:23527032 |
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NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
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G |
Tpd52l1 |
TPD52 like 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TPD52L1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
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G |
Tph1 |
tryptophan hydroxylase 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of TPH1 mRNA |
CTD |
PMID:33901603 |
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NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
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G |
Tph2 |
tryptophan hydroxylase 2 |
decreases expression |
EXP |
Lithium Chloride results in decreased expression of TPH2 mRNA; Lithium Chloride results in decreased expression of TPH2 protein |
CTD |
PMID:19840776 |
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NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
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G |
Tpm1 |
tropomyosin 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TPM1 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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G |
Trib3 |
tribbles pseudokinase 3 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TRIB3 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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G |
Trim6 |
tripartite motif containing 6 |
increases expression |
ISO |
Lithium Chloride results in increased expression of TRIM6 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
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G |
Tsc22d3 |
TSC22 domain family, member 3 |
multiple interactions |
ISO |
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] |
CTD |
PMID:29957541 |
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NCBI chr X:104,217,898...104,277,935
Ensembl chr X:104,217,925...104,276,861
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
decreases expression multiple interactions |
ISO |
Lithium Chloride results in decreased expression of UGCG mRNA [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of UGCG mRNA |
CTD |
PMID:15711924 PMID:26074776 |
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NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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G |
Utp3 |
UTP3, small subunit processome component |
increases expression |
ISO |
Lithium Chloride results in increased expression of UTP3 mRNA |
CTD |
PMID:27226553 |
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NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of VCAM1 mRNA |
CTD |
PMID:33901603 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO |
Lithium Chloride results in increased expression of VEGFA protein Lithium Chloride results in increased expression of VEGFA mRNA |
CTD |
PMID:20696143 PMID:26272751 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
increases expression decreases expression multiple interactions |
EXP ISO |
Lithium Chloride results in increased expression of VIM protein Lithium Chloride results in decreased expression of VIM mRNA Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of VIM protein] |
CTD |
PMID:8773480 PMID:23527032 PMID:32112862 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Vpreb1 |
V-set pre-B cell surrogate light chain 1 |
increases expression |
ISO |
Lithium Chloride results in increased expression of VPREB1 mRNA |
CTD |
PMID:27226553 |
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NCBI chr11:84,126,969...84,127,846
Ensembl chr11:84,126,969...84,127,846
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G |
Wnt1 |
Wnt family member 1 |
multiple interactions |
ISO |
Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of WNT1 protein] |
CTD |
PMID:28343033 |
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NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
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G |
Wnt3 |
Wnt family member 3 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of WNT3 mRNA |
CTD |
PMID:26272751 |
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NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099
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G |
Xrcc4 |
X-ray repair cross complementing 4 |
increases expression |
EXP |
Lithium Chloride results in increased expression of XRCC4 mRNA |
CTD |
PMID:19285016 |
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NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
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G |
Ybx1 |
Y box binding protein 1 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of YBX1 mRNA |
CTD |
PMID:23527032 |
|
NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
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G |
Zfp207 |
zinc finger protein 207 |
increases expression |
ISO |
Lithium Chloride results in increased expression of ZNF207 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr10:65,385,823...65,397,591
Ensembl chr10:65,385,740...65,397,386
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G |
Zfp423 |
zinc finger protein 423 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ZNF423 mRNA |
CTD |
PMID:23527032 |
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NCBI chr19:19,111,538...19,407,371
Ensembl chr19:19,110,238...19,407,373
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G |
Zmynd8 |
zinc finger, MYND-type containing 8 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ZMYND8 mRNA |
CTD |
PMID:15711924 |
|
NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
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G |
Zscan22 |
zinc finger and SCAN domain containing 22 |
decreases expression |
ISO |
Lithium Chloride results in decreased expression of ZSCAN22 mRNA |
CTD |
PMID:23527032 |
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NCBI chr 1:73,516,335...73,527,766
Ensembl chr 1:73,516,395...73,527,697
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