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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenformin
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Accession:CHEBI:8064 term browser browse the term
Definition:A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of lactic acidosis.
Synonyms:exact_synonym: N-(2-phenylethyl)imidodicarbonimidic diamide
 related_synonym: DBI;   Formula=C10H15N5;   InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15);   InChIKey=ICFJFFQQTFMIBG-UHFFFAOYSA-N;   SMILES=NC(=N)NC(=N)NCCC1=CC=CC=C1;   fenformina;   phenformine;   phenforminum
 xref: CAS:114-86-3;   DrugBank:DB00914;   Drug_Central:2126;   HMDB:HMDB0015050;   KEGG:C07673;   KEGG:D08351;   LINCS:LSM-2233
 xref_mesh: MESH:D010629
 xref: PDBeChem:8CV;   PMID:16567854;   PMID:18239244;   PMID:20188727;   PMID:21084729;   PMID:22036620;   PMID:22361631;   PMID:23322141;   PMID:23475884;   PMID:23548904;   PMID:23612073;   PMID:28766937;   PMID:7390164;   Patent:US2961377;   Patent:US3057780;   Patent:WO2010114805;   Reaxys:1977317;   Wikipedia:Phenformin



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phenformin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Phenformin results in decreased expression of A2M mRNA CTD PMID:31324951 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Phenformin results in increased expression of ABCB4 mRNA CTD PMID:31324951 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Phenformin results in increased expression of ABCC3 mRNA CTD PMID:31324951 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 increases expression EXP Phenformin results in increased expression of ABCD2 mRNA CTD PMID:31324951 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression EXP Phenformin results in decreased expression of ABCG2 mRNA CTD PMID:31324951 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Phenformin results in increased expression of ABCG5 mRNA CTD PMID:31324951 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Phenformin results in increased expression of ABCG8 mRNA CTD PMID:31324951 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Abra actin-binding Rho activating protein decreases expression EXP Phenformin results in decreased expression of ABRA mRNA CTD PMID:31324951 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP Phenformin results in decreased expression of ACACA mRNA CTD PMID:31324951 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ackr3 atypical chemokine receptor 3 decreases expression EXP Phenformin results in decreased expression of ACKR3 mRNA CTD PMID:31324951 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Acly ATP citrate lyase decreases expression EXP Phenformin results in decreased expression of ACLY mRNA CTD PMID:31324951 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP Phenformin results in increased expression of ACMSD mRNA CTD PMID:31324951 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP Phenformin results in decreased expression of ACSL3 mRNA CTD PMID:31324951 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP Phenformin results in decreased expression of ACTG1 mRNA CTD PMID:31324951 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP Phenformin results in decreased expression of ADAMTS1 mRNA CTD PMID:31324951 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP Phenformin results in increased expression of ADH4 mRNA CTD PMID:31324951 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) increases expression EXP Phenformin results in increased expression of ADH6 mRNA CTD PMID:31324951 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Afmid arylformamidase decreases expression EXP Phenformin results in decreased expression of AFMID mRNA CTD PMID:31324951 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Agxt alanine--glyoxylate aminotransferase increases expression EXP Phenformin results in increased expression of AGXT mRNA CTD PMID:31324951 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Akr1b8-ps2 aldo-keto reductase family 1, member B8, pseudogene 2 decreases expression EXP Phenformin results in decreased expression of AKR1B8-PS2 mRNA CTD PMID:31324951 NCBI chr 6:77,569,720...77,571,967 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP Phenformin results in decreased expression of ALAS2 mRNA CTD PMID:31324951 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Phenformin results in increased expression of ALDH1A1 mRNA CTD PMID:31324951 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Phenformin results in decreased expression of ALOX15 mRNA CTD PMID:31324951 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Amacr alpha-methylacyl-CoA racemase increases expression EXP Phenformin results in increased expression of AMACR mRNA CTD PMID:31324951 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Amdhd1 amidohydrolase domain containing 1 increases expression EXP Phenformin results in increased expression of AMDHD1 mRNA CTD PMID:31324951 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP Phenformin affects the expression of ANGPTL4 mRNA CTD PMID:31324951 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Angptl8 angiopoietin-like 8 decreases expression EXP Phenformin results in decreased expression of ANGPTL8 mRNA CTD PMID:31324951 NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP Phenformin results in decreased expression of ANKH mRNA CTD PMID:31324951 NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187
JBrowse link
G Anlnl1 anillin, actin binding protein-like 1 decreases expression EXP Phenformin results in decreased expression of ANLNL1 mRNA CTD PMID:31324951 NCBI chr17:57,985,340...57,995,824
Ensembl chr17:57,986,511...57,989,997
JBrowse link
G Ano5 anoctamin 5 decreases expression EXP Phenformin results in decreased expression of ANO5 mRNA CTD PMID:31324951 NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555
JBrowse link
G Apcdd1 APC down-regulated 1 increases expression EXP Phenformin results in increased expression of APCDD1 mRNA CTD PMID:31324951 NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit decreases expression EXP Phenformin results in decreased expression of APH1B mRNA CTD PMID:31324951 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G Aplnr apelin receptor increases expression EXP Phenformin results in increased expression of APLNR mRNA CTD PMID:31324951 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP Phenformin results in decreased expression of APOA4 mRNA CTD PMID:31324951 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc4 apolipoprotein C4 increases expression EXP Phenformin results in increased expression of APOC4 mRNA CTD PMID:31324951 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
JBrowse link
G Apof apolipoprotein F increases expression EXP Phenformin results in increased expression of APOF mRNA CTD PMID:31324951 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946
JBrowse link
G Apold1 apolipoprotein L domain containing 1 decreases expression EXP Phenformin results in decreased expression of APOLD1 mRNA CTD PMID:31324951 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G Aqp7 aquaporin 7 increases expression EXP Phenformin results in increased expression of AQP7 mRNA CTD PMID:31324951 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Aqp9 aquaporin 9 increases expression EXP Phenformin results in increased expression of AQP9 mRNA CTD PMID:31324951 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Ar androgen receptor decreases expression EXP Phenformin results in decreased expression of AR mRNA CTD PMID:31324951 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression EXP Phenformin results in decreased expression of ARHGAP11A mRNA CTD PMID:31324951 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression EXP Phenformin results in increased expression of ARRDC4 mRNA CTD PMID:31324951 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asl argininosuccinate lyase increases expression EXP Phenformin results in increased expression of ASL mRNA CTD PMID:31324951 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression EXP Phenformin results in decreased expression of ASPM mRNA CTD PMID:31324951 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Aspn asporin decreases expression EXP Phenformin results in decreased expression of ASPN mRNA CTD PMID:31324951 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
JBrowse link
G Atf3 activating transcription factor 3 decreases expression EXP Phenformin results in decreased expression of ATF3 mRNA CTD PMID:31324951 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Aurkb aurora kinase B decreases expression EXP Phenformin results in decreased expression of AURKB mRNA CTD PMID:31324951 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bex2 brain expressed X-linked 2 increases expression EXP Phenformin results in increased expression of BEX1 mRNA CTD PMID:31324951 NCBI chr  X:99,019,847...99,021,375
Ensembl chr  X:99,019,000...99,021,503
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP Phenformin results in decreased expression of BHLHE40 mRNA CTD PMID:31324951 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP Phenformin results in decreased expression of BTG2 mRNA CTD PMID:31324951 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression EXP Phenformin results in decreased expression of BUB1 mRNA CTD PMID:31324951 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G C8h11orf54 similar to human chromosome 11 open reading frame 54 decreases expression EXP Phenformin results in decreased expression of C8H11ORF54 mRNA CTD PMID:31324951 NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
JBrowse link
G Car5a carbonic anhydrase 5A increases expression EXP Phenformin results in increased expression of CAR5A mRNA CTD PMID:31324951 NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
JBrowse link
G Car5b carbonic anhydrase 5B decreases expression EXP Phenformin results in decreased expression of CAR5B mRNA CTD PMID:31324951 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837
JBrowse link
G Ccdc141 coiled-coil domain containing 141 decreases expression EXP Phenformin results in decreased expression of CCDC141 mRNA CTD PMID:31324951 NCBI chr 3:61,948,614...62,109,968
Ensembl chr 3:61,948,646...62,110,079
JBrowse link
G Ccdc38 coiled-coil domain containing 38 increases expression EXP Phenformin results in increased expression of CCDC38 mRNA CTD PMID:31324951 NCBI chr 7:28,055,883...28,129,938
Ensembl chr 7:28,059,798...28,130,441
JBrowse link
G Ccdc77 coiled-coil domain containing 77 increases expression EXP Phenformin results in increased expression of CCDC77 mRNA CTD PMID:31324951 NCBI chr 4:153,534,184...153,566,059
Ensembl chr 4:153,534,187...153,566,545
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Phenformin results in decreased expression of CCL2 mRNA CTD PMID:31324951 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP Phenformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP Phenformin results in decreased expression of CCNA2 mRNA CTD PMID:31324951 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP Phenformin results in decreased expression of CCNB1 mRNA CTD PMID:31324951 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 affects expression EXP Phenformin affects the expression of CCNB2 mRNA CTD PMID:31324951 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Phenformin results in increased expression of CCND1 mRNA CTD PMID:31324951 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne2 cyclin E2 decreases expression EXP Phenformin results in decreased expression of CCNE2 mRNA CTD PMID:31324951 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd226 CD226 molecule decreases expression EXP Phenformin results in decreased expression of CD226 mRNA CTD PMID:31324951 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Cd274 CD274 molecule increases expression EXP Phenformin results in increased expression of CD274 mRNA CTD PMID:31324951 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd5l Cd5 molecule-like increases expression EXP Phenformin results in increased expression of CD5L mRNA CTD PMID:31324951 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753
JBrowse link
G Cd63 Cd63 molecule increases expression EXP Phenformin results in increased expression of CD63 mRNA CTD PMID:31324951 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
JBrowse link
G Cd74 CD74 molecule increases expression EXP Phenformin results in increased expression of CD74 mRNA CTD PMID:31324951 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP Phenformin results in decreased expression of CDC20 mRNA CTD PMID:31324951 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Phenformin results in decreased expression of CDK1 mRNA CTD PMID:31324951 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO
EXP
Phenformin results in increased expression of CDKN1A protein
Phenformin results in decreased expression of CDKN1A mRNA
CTD PMID:14623034 PMID:31324951 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Phenformin results in decreased expression of CDKN3 mRNA CTD PMID:31324951 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression EXP Phenformin results in decreased expression of CEMIP2 mRNA CTD PMID:31324951 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Cenpe centromere protein E decreases expression EXP Phenformin results in decreased expression of CENPE mRNA CTD PMID:31324951 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenpf centromere protein F decreases expression EXP Phenformin results in decreased expression of CENPF mRNA CTD PMID:31324951 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP Phenformin results in increased expression of CES2C mRNA CTD PMID:31324951 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Ces4a carboxylesterase 4A decreases expression EXP Phenformin results in decreased expression of CES4A mRNA CTD PMID:31324951 NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545
JBrowse link
G Chka choline kinase alpha decreases expression EXP Phenformin results in decreased expression of CHKA mRNA CTD PMID:31324951 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression EXP Phenformin results in decreased expression of CISH mRNA CTD PMID:31324951 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression EXP Phenformin results in decreased expression of CKAP2 mRNA CTD PMID:31324951 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP Phenformin results in decreased expression of CKS2 mRNA CTD PMID:31324951 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clec1a C-type lectin domain family 1, member A decreases expression EXP Phenformin results in decreased expression of CLEC1A mRNA CTD PMID:31324951 NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247
JBrowse link
G Clec1b C-type lectin domain family 1, member B decreases expression EXP Phenformin results in decreased expression of CLEC1B mRNA CTD PMID:31324951 NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291
JBrowse link
G Cpne8 copine 8 increases expression EXP Phenformin results in increased expression of CPNE8 mRNA CTD PMID:31324951 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Phenformin results in increased expression of CPT1A mRNA CTD PMID:31324951 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP Phenformin results in increased expression of CRAT mRNA CTD PMID:31324951 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression EXP Phenformin results in increased expression of CROT mRNA CTD PMID:31324951 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP Phenformin results in decreased expression of CRY1 mRNA CTD PMID:31324951 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP Phenformin results in increased expression of CRYL1 mRNA CTD PMID:31324951 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP Phenformin results in decreased expression of CSAD mRNA CTD PMID:31324951 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP Phenformin results in decreased expression of CSRP1 mRNA CTD PMID:31324951 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Phenformin results in decreased expression of CXCL1 mRNA CTD PMID:31324951 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Phenformin results in decreased expression of CXCL10 mRNA CTD PMID:31324951 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP Phenformin results in increased expression of CXCR4 mRNA CTD PMID:31324951 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Phenformin results in decreased expression of CYP17A1 mRNA CTD PMID:31324951 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP2B1 mRNA CTD PMID:31324951 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP Phenformin results in decreased expression of CYP2C12 mRNA CTD PMID:31324951 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression EXP Phenformin results in increased expression of CYP2C24 mRNA CTD PMID:31324951 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP2E1 mRNA CTD PMID:31324951 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP Phenformin results in increased expression of CYP3A18 mRNA CTD PMID:31324951 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP4A1 mRNA CTD PMID:31324951 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP Phenformin results in increased expression of CYP4A2 mRNA CTD PMID:31324951 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP Phenformin results in decreased expression of CYP7A1 mRNA CTD PMID:31324951 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression EXP Phenformin results in increased expression of CYP8B1 mRNA CTD PMID:31324951 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP Phenformin results in increased expression of DBP mRNA CTD PMID:31324951 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcn decorin decreases expression EXP Phenformin results in decreased expression of DCN mRNA CTD PMID:31324951 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddhd1 DDHD domain containing 1 increases expression EXP Phenformin results in increased expression of DDHD1 mRNA CTD PMID:31324951 NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression EXP Phenformin results in decreased expression of DDIT4 mRNA CTD PMID:31324951 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP Phenformin results in increased expression of DECR1 mRNA CTD PMID:31324951 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression EXP Phenformin results in decreased expression of DEPDC1 mRNA CTD PMID:31324951 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression EXP Phenformin results in decreased expression of DIAPH3 mRNA CTD PMID:31324951 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP Phenformin results in decreased expression of DIO1 mRNA CTD PMID:31324951 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP Phenformin results in increased expression of DMBT1 mRNA CTD PMID:31324951 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
JBrowse link
G Dmxl2 Dmx-like 2 decreases expression EXP Phenformin results in decreased expression of DMXL2 mRNA CTD PMID:31324951 NCBI chr 8:54,741,164...54,884,948
Ensembl chr 8:54,741,160...54,885,161
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Phenformin results in decreased expression of DUSP1 mRNA CTD PMID:31324951 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Phenformin results in increased expression of ECH1 mRNA CTD PMID:31324951 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP Phenformin results in increased expression of ECI1 mRNA CTD PMID:31324951 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression EXP Phenformin results in decreased expression of ECT2 mRNA CTD PMID:31324951 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression EXP Phenformin results in decreased expression of EDEM1 mRNA CTD PMID:31324951 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 decreases expression EXP Phenformin results in decreased expression of EDIL3 mRNA CTD PMID:31324951 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008
JBrowse link
G Egr1 early growth response 1 decreases expression EXP Phenformin results in decreased expression of EGR1 mRNA CTD PMID:31324951 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression EXP Phenformin results in decreased expression of ELL2 mRNA CTD PMID:31324951 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 increases expression EXP Phenformin results in increased expression of ELOVL2 mRNA CTD PMID:31324951 NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP Phenformin results in decreased expression of ELOVL6 mRNA CTD PMID:31324951 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Erich5 glutamate-rich 5 decreases expression EXP Phenformin results in decreased expression of ERICH5 mRNA CTD PMID:31324951 NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP Phenformin results in decreased expression of ERRFI1 mRNA CTD PMID:31324951 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression EXP Phenformin results in decreased expression of ESCO2 mRNA CTD PMID:31324951 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression EXP Phenformin results in increased expression of ESM1 mRNA CTD PMID:31324951 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression EXP Phenformin results in decreased expression of F2RL2 mRNA CTD PMID:31324951 NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression EXP Phenformin results in decreased expression of F3 mRNA CTD PMID:31324951 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP Phenformin results in decreased expression of FABP5 mRNA CTD PMID:31324951 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fam111a FAM111 trypsin like peptidase A decreases expression EXP Phenformin results in decreased expression of FAM111A mRNA CTD PMID:31324951 NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547
JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression EXP Phenformin results in increased expression of FAM117B mRNA CTD PMID:31324951 NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483
JBrowse link
G Fam149a family with sequence similarity 149, member A decreases expression EXP Phenformin results in decreased expression of FAM149A mRNA CTD PMID:31324951 NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression EXP Phenformin results in decreased expression of FAM83D mRNA CTD PMID:31324951 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fasn fatty acid synthase decreases expression EXP Phenformin results in decreased expression of FASN mRNA CTD PMID:31324951 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fgf6 fibroblast growth factor 6 increases expression EXP Phenformin results in increased expression of MT1F mRNA CTD PMID:31324951 NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression EXP Phenformin results in decreased expression of FMO2 mRNA CTD PMID:31324951 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP Phenformin results in increased expression of FMO5 mRNA CTD PMID:31324951 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of FOS mRNA CTD PMID:31324951 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxa1 forkhead box A1 decreases expression EXP Phenformin results in decreased expression of FOXA1 mRNA CTD PMID:31324951 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP Phenformin results in decreased expression of FOXA2 mRNA CTD PMID:31324951 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxo3 forkhead box O3 decreases expression EXP Phenformin results in decreased expression of FOXO3 mRNA CTD PMID:31324951 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fpr1 formyl peptide receptor 1 decreases expression EXP Phenformin results in decreased expression of FPR1 mRNA CTD PMID:31324951 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 decreases expression EXP Phenformin results in decreased expression of FRAS1 mRNA CTD PMID:31324951 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Phenformin results in decreased expression of G6PC1 mRNA CTD PMID:31324951 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP Phenformin results in decreased expression of GADD45G mRNA CTD PMID:31324951 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression EXP Phenformin results in decreased expression of GBE1 mRNA CTD PMID:31324951 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression EXP Phenformin results in increased expression of GBP1 mRNA CTD PMID:31324951 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131
JBrowse link
G Gbp1-ps1 guanylate binding protein 1, pseudogene 1 increases expression EXP Phenformin results in increased expression of GBP1-PS1 mRNA CTD PMID:31324951 NCBI chr 2:231,517,485...231,525,865
Ensembl chr 2:231,517,398...231,529,600
JBrowse link
G Gck glucokinase decreases expression EXP Phenformin results in decreased expression of GCK mRNA CTD PMID:31324951 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gimd1 GIMAP family P-loop NTPase domain containing 1 decreases expression EXP Phenformin results in decreased expression of GIMD1 mRNA CTD PMID:31324951 NCBI chr 2:221,103,878...221,138,559
Ensembl chr 2:221,103,878...221,138,553
JBrowse link
G Gk glycerol kinase increases expression EXP Phenformin results in increased expression of GK mRNA CTD PMID:31324951 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gnmt glycine N-methyltransferase increases expression EXP Phenformin results in increased expression of GNMT mRNA CTD PMID:31324951 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP Phenformin results in increased expression of GOT1 mRNA CTD PMID:31324951 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gp5 glycoprotein V (platelet) decreases expression EXP Phenformin results in decreased expression of GP5 mRNA CTD PMID:31324951 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Gpa33 glycoprotein A33 increases expression EXP Phenformin results in increased expression of GPA33 mRNA CTD PMID:31324951 NCBI chr13:78,381,141...78,414,765
Ensembl chr13:78,381,141...78,414,765
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Phenformin results in increased expression of GPAM mRNA CTD PMID:31324951 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression EXP Phenformin results in increased expression of GPAT3 mRNA CTD PMID:31324951 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression EXP Phenformin results in increased expression of GPD2 mRNA CTD PMID:31324951 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Phenformin results in increased expression of GPNMB mRNA CTD PMID:31324951 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gprin3 GPRIN family member 3 decreases expression EXP Phenformin results in decreased expression of GPRIN3 mRNA CTD PMID:31324951 NCBI chr 4:88,572,062...88,657,369
Ensembl chr 4:88,563,607...88,657,429
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP Phenformin results in increased expression of GPT mRNA CTD PMID:31324951 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx2-ps2 glutathione peroxidase 2, pseudogene 2 affects expression EXP Phenformin affects the expression of GPX2-PS2 mRNA CTD PMID:31324951 NCBI chr  X:59,444,660...59,445,203 JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Phenformin results in increased expression of GSTM2 mRNA CTD PMID:31324951 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression EXP Phenformin results in increased expression of GSTM4 mRNA CTD PMID:31324951 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression EXP Phenformin results in increased expression of GSTZ1 mRNA CTD PMID:31324951 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Gypa glycophorin A decreases expression EXP Phenformin results in decreased expression of GYPA mRNA CTD PMID:31324951 NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
JBrowse link
G H2ac4 H2A clustered histone 4 decreases expression EXP Phenformin results in decreased expression of H2AC4 mRNA CTD PMID:31324951 NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381
JBrowse link
G H2ax H2A.X variant histone decreases expression EXP Phenformin results in decreased expression of H2AX mRNA CTD PMID:31324951 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP Phenformin results in decreased expression of HAMP mRNA CTD PMID:31324951 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Phenformin results in decreased expression of HBB-B1 mRNA CTD PMID:31324951 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP Phenformin results in decreased expression of HHEX mRNA CTD PMID:31324951 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Phenformin results in increased expression of HIF1A protein CTD PMID:26768367 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression EXP Phenformin results in decreased expression of HIST1H2AF mRNA CTD PMID:31324951 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 decreases expression EXP Phenformin results in decreased expression of HIST1H2AIL1 mRNA CTD PMID:31324951 NCBI chr17:41,568,181...41,569,093
Ensembl chr17:41,568,471...41,569,109
JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 decreases expression EXP Phenformin results in decreased expression of HIST2H3C2 mRNA CTD PMID:31324951 NCBI chr 2:183,837,296...183,837,721
Ensembl chr 2:183,837,303...183,837,752
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression EXP Phenformin results in decreased expression of HLF mRNA CTD PMID:31324951 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP Phenformin results in decreased expression of HMGCR mRNA CTD PMID:31324951 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression EXP Phenformin results in decreased expression of HMMR mRNA CTD PMID:31324951 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression EXP Phenformin results in increased expression of HSD17B2 mRNA CTD PMID:31324951 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP Phenformin results in decreased expression of HSP90AA1 mRNA CTD PMID:31324951 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like decreases expression EXP Phenformin results in decreased expression of HSPA4L mRNA CTD PMID:31324951 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hykk hydroxylysine kinase increases expression EXP Phenformin results in increased expression of HYKK mRNA CTD PMID:31324951 NCBI chr 8:55,315,919...55,339,720
Ensembl chr 8:55,315,969...55,337,339
JBrowse link
G Ier2 immediate early response 2 decreases expression EXP Phenformin results in decreased expression of IER2 mRNA CTD PMID:31324951 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Ifgga4l interferon-gamma-inducible GTPase 4 like increases expression EXP Phenformin results in increased expression of IFGGA4L mRNA CTD PMID:31324951 NCBI chr18:53,838,426...53,854,858
Ensembl chr18:53,851,449...53,852,696
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression EXP Phenformin results in increased expression of IFITM3 mRNA CTD PMID:31324951 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 decreases expression EXP Phenformin results in decreased expression of IGF2BP3 mRNA CTD PMID:31324951 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP Phenformin results in decreased expression of IGFALS mRNA CTD PMID:31324951 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP Phenformin results in increased expression of IGFBP2 mRNA CTD PMID:31324951 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP Phenformin results in decreased expression of IGFBP5 mRNA CTD PMID:31324951 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression EXP Phenformin results in increased expression of IL1R1 mRNA CTD PMID:31324951 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il33 interleukin 33 increases expression EXP Phenformin results in increased expression of IL33 mRNA CTD PMID:31324951 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Phenformin results in decreased expression of INHA mRNA CTD PMID:31324951 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP Phenformin results in decreased expression of INHBA mRNA CTD PMID:31324951 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbe inhibin subunit beta E increases expression EXP Phenformin results in increased expression of INHBE mRNA CTD PMID:31324951 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP Phenformin results in increased expression of INMT mRNA CTD PMID:31324951 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP Phenformin results in decreased expression of INSIG1 mRNA CTD PMID:31324951 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP Phenformin results in increased expression of INSIG2 mRNA CTD PMID:31324951 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 decreases expression EXP Phenformin results in decreased expression of IP6K2 mRNA CTD PMID:31324951 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression EXP Phenformin results in decreased expression of IRF2BP2 mRNA CTD PMID:31324951 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642
JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like decreases expression EXP Phenformin results in decreased expression of IRF2BPL mRNA CTD PMID:31324951 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
JBrowse link
G Irs2 insulin receptor substrate 2 decreases expression EXP Phenformin results in decreased expression of IRS2 mRNA CTD PMID:31324951 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of JUN mRNA CTD PMID:31324951 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of JUNB mRNA CTD PMID:31324951 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 increases expression EXP Phenformin results in increased expression of KCNA2 mRNA CTD PMID:31324951 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression EXP Phenformin results in increased expression of KCNJ5 mRNA CTD PMID:31324951 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kif11 kinesin family member 11 decreases expression EXP Phenformin results in decreased expression of KIF11 mRNA CTD PMID:31324951 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP Phenformin results in decreased expression of KIF20A mRNA CTD PMID:31324951 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif20b kinesin family member 20B decreases expression EXP Phenformin results in decreased expression of KIF20B mRNA CTD PMID:31324951 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif23 kinesin family member 23 decreases expression EXP Phenformin results in decreased expression of KIF23 mRNA CTD PMID:31324951 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Knl1 kinetochore scaffold 1 decreases expression EXP Phenformin results in decreased expression of KNL1 mRNA CTD PMID:31324951 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Krt18 keratin 18 increases expression EXP Phenformin results in increased expression of KRT18 mRNA CTD PMID:31324951 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP Phenformin results in increased expression of LBP mRNA CTD PMID:31324951 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lepr leptin receptor increases response to substance EXP LEPR gene mutant form results in increased susceptibility to Phenformin CTD PMID:29743445 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals5 galectin 5 decreases expression EXP Phenformin results in decreased expression of LGALS5 mRNA CTD PMID:31324951 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression EXP Phenformin results in decreased expression of LGSN mRNA CTD PMID:31324951 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
JBrowse link
G Lipo1 lipase, member O1 decreases expression EXP Phenformin results in decreased expression of LIPO1 mRNA CTD PMID:31324951 NCBI chr 1:231,311,828...231,328,805
Ensembl chr 1:231,311,315...231,325,187
JBrowse link
G Loxl4 lysyl oxidase-like 4 increases expression EXP Phenformin results in increased expression of LOXL4 mRNA CTD PMID:31324951 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 increases expression EXP Phenformin results in increased expression of LPAR6 mRNA CTD PMID:31324951 NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
JBrowse link
G Lpin1 lipin 1 decreases expression EXP Phenformin results in decreased expression of LPIN1 mRNA CTD PMID:31324951 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lum lumican decreases expression EXP Phenformin results in decreased expression of LUM mRNA CTD PMID:31324951 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like decreases expression EXP Phenformin results in decreased expression of LURAP1L mRNA CTD PMID:31324951 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
JBrowse link
G Ly6c Ly6-C antigen increases expression EXP Phenformin results in increased expression of LY6C mRNA CTD PMID:31324951 NCBI chr 7:106,959,508...106,963,329
Ensembl chr 7:106,959,511...106,963,329
JBrowse link
G Lynx1 Ly6/neurotoxin 1 decreases expression EXP Phenformin results in decreased expression of LYNX1 mRNA CTD PMID:31324951 NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like decreases expression EXP Phenformin results in decreased expression of MASTL mRNA CTD PMID:31324951 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 increases expression EXP Phenformin results in increased expression of MBNL3 mRNA CTD PMID:31324951 NCBI chr  X:130,641,942...130,737,179
Ensembl chr  X:130,648,538...130,737,056
JBrowse link
G Mest mesoderm specific transcript decreases expression EXP Phenformin results in decreased expression of MEST mRNA CTD PMID:31324951 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression EXP Phenformin results in decreased expression of MFAP4 mRNA CTD PMID:31324951 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid decreases expression EXP Phenformin results in decreased expression of MFSD2A mRNA CTD PMID:31324951 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B decreases expression EXP Phenformin results in decreased expression of MGAT4B mRNA CTD PMID:31324951 NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229
JBrowse link
G Mgp matrix Gla protein decreases expression EXP Phenformin results in decreased expression of MGP mRNA CTD PMID:31324951 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mir15b microRNA 15b increases expression EXP Phenformin results in increased expression of MIR15B mRNA CTD PMID:31324951 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir29b2 microRNA 29b-2 increases expression EXP Phenformin results in increased expression of MIR29B2 mRNA CTD PMID:31324951 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression EXP Phenformin results in increased expression of MIRLET7C-1 mRNA CTD PMID:31324951 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Phenformin results in decreased expression of MKI67 mRNA CTD PMID:31324951 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases expression EXP Phenformin results in decreased expression of MKNK2 mRNA CTD PMID:31324951 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression EXP Phenformin results in decreased expression of MLXIPL mRNA CTD PMID:31324951 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mst1r macrophage stimulating 1 receptor decreases expression EXP Phenformin results in decreased expression of MST1R mRNA CTD PMID:31324951 NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Phenformin results in increased expression of MT1A mRNA CTD PMID:31324951 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 increases expression EXP Phenformin results in increased expression of MT1M mRNA CTD PMID:31324951 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Mt2A metallothionein 2A increases expression EXP Phenformin results in increased expression of MT2A mRNA CTD PMID:31324951 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression EXP Phenformin results in decreased expression of MTSS1 mRNA CTD PMID:31324951 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
JBrowse link
G Mx2 MX dynamin like GTPase 2 increases expression EXP Phenformin results in increased expression of MX2 mRNA CTD PMID:31324951 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Phenformin results in decreased expression of MYC mRNA CTD PMID:31324951 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Phenformin results in increased expression of MYH7 mRNA CTD PMID:31324951 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myoc myocilin increases expression EXP Phenformin results in increased expression of MYOC mRNA CTD PMID:31324951 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Myom2 myomesin 2 increases expression EXP Phenformin results in increased expression of MYOM2 mRNA CTD PMID:31324951 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression EXP Phenformin results in decreased expression of NCAPG mRNA CTD PMID:31324951 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression EXP Phenformin results in increased expression of NCF1 mRNA CTD PMID:31324951 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression EXP Phenformin results in decreased expression of NDC80 mRNA CTD PMID:31324951 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO Phenformin results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression EXP Phenformin results in decreased expression of NFKBIA mRNA CTD PMID:31324951 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor decreases expression EXP Phenformin results in decreased expression of NGEF mRNA CTD PMID:31324951 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
JBrowse link
G Noct nocturnin decreases expression EXP Phenformin results in decreased expression of NOCT mRNA CTD PMID:31324951 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Nppa natriuretic peptide A increases expression EXP Phenformin results in increased expression of NPPA mRNA CTD PMID:31324951 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Npr3 natriuretic peptide receptor 3 increases expression EXP Phenformin results in increased expression of NPR3 mRNA CTD PMID:31324951 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Npy neuropeptide Y affects expression EXP Phenformin affects the expression of NPY mRNA CTD PMID:31324951 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Phenformin results in increased expression of NQO1 mRNA CTD PMID:31324951 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Phenformin results in increased expression of NR1D1 mRNA CTD PMID:31324951 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP Phenformin results in increased expression of NR1D2 mRNA CTD PMID:31324951 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression EXP Phenformin results in decreased expression of NR4A1 mRNA CTD PMID:31324951 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP Phenformin results in decreased expression of NR4A2 mRNA CTD PMID:31324951 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression EXP Phenformin results in decreased expression of NR4A3 mRNA CTD PMID:31324951 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression EXP Phenformin results in decreased expression of NUF2 mRNA CTD PMID:31324951 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression EXP Phenformin results in decreased expression of NUSAP1 mRNA CTD PMID:31324951 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Oaf out at first homolog increases expression EXP Phenformin results in increased expression of OAF mRNA CTD PMID:31324951 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Oat ornithine aminotransferase increases expression EXP Phenformin results in increased expression of OAT mRNA CTD PMID:31324951 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Olr906 olfactory receptor 906 increases expression EXP Phenformin results in increased expression of OLR906 mRNA CTD PMID:31324951 NCBI chr 7:1,821,264...1,822,202
Ensembl chr 7:1,821,264...1,822,202
JBrowse link
G Omd osteomodulin decreases expression EXP Phenformin results in decreased expression of OMD mRNA CTD PMID:31324951 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like decreases expression EXP Phenformin results in decreased expression of OPCML mRNA CTD PMID:31324951 NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 decreases expression EXP Phenformin results in decreased expression of OSBPL3 mRNA CTD PMID:31324951 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Phenformin results in decreased expression of OSGIN1 mRNA CTD PMID:31324951 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Otud1 OTU deubiquitinase 1 decreases expression EXP Phenformin results in decreased expression of OTUD1 mRNA CTD PMID:31324951 NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP Phenformin results in increased expression of P2RX7 mRNA CTD PMID:31324951 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G P2ry2 purinergic receptor P2Y2 increases expression EXP Phenformin results in increased expression of P2RY2 mRNA CTD PMID:31324951 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 decreases expression EXP Phenformin results in decreased expression of PAQR9 mRNA CTD PMID:31324951 NCBI chr 8:96,114,249...96,116,546 JBrowse link
G Pbk PDZ binding kinase decreases expression EXP Phenformin results in decreased expression of PBK mRNA CTD PMID:31324951 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP Phenformin results in increased expression of PBLD1 mRNA CTD PMID:31324951 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression EXP Phenformin results in decreased expression of PCLAF mRNA CTD PMID:31324951 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pde4b phosphodiesterase 4B increases expression EXP Phenformin results in increased expression of PDE4B mRNA CTD PMID:31324951 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Phenformin results in increased expression of PDK4 mRNA CTD PMID:31324951 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP Phenformin results in decreased expression of PDLIM1 mRNA CTD PMID:31324951 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP Phenformin results in decreased expression of PDLIM3 mRNA CTD PMID:31324951 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 increases expression EXP Phenformin results in increased expression of PDZRN3 mRNA CTD PMID:31324951 NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959
JBrowse link
G Penk proenkephalin increases expression EXP Phenformin results in increased expression of PENK mRNA CTD PMID:31324951 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Per1 period circadian regulator 1 decreases expression EXP Phenformin results in decreased expression of PER1 mRNA CTD PMID:31324951 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Per2 period circadian regulator 2 decreases expression EXP Phenformin results in decreased expression of PER2 mRNA CTD PMID:31324951 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression EXP Phenformin results in increased expression of PEX11A mRNA CTD PMID:31324951 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pex16 peroxisomal biogenesis factor 16 increases expression EXP Phenformin results in increased expression of PEX16 mRNA CTD PMID:31324951 NCBI chr 3:78,347,212...78,352,603
Ensembl chr 3:78,343,164...78,353,207
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Phenformin results in decreased expression of PF4 mRNA CTD PMID:31324951 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases expression EXP Phenformin results in decreased expression of PFKFB1 mRNA CTD PMID:31324951 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 decreases expression EXP Phenformin results in decreased expression of PHTF1 mRNA CTD PMID:31324951 NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
JBrowse link
G Pi15 peptidase inhibitor 15 decreases expression EXP Phenformin results in decreased expression of PI15 mRNA CTD PMID:31324951 NCBI chr 5:1,395,094...1,423,213
Ensembl chr 5:1,395,094...1,423,213
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP Phenformin results in decreased expression of PIK3R1 mRNA CTD PMID:31324951 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP Phenformin results in decreased expression of PKLR mRNA CTD PMID:31324951 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP Phenformin results in increased expression of PLA2G12A mRNA CTD PMID:31324951 NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plin2 perilipin 2 decreases expression EXP Phenformin results in decreased expression of PLIN2 mRNA CTD PMID:31324951 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plk1 polo-like kinase 1 decreases expression EXP Phenformin results in decreased expression of PLK1 mRNA CTD PMID:31324951 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression EXP Phenformin results in decreased expression of PLPPR1 mRNA CTD PMID:31324951 NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression EXP Phenformin results in decreased expression of PNPLA3 mRNA CTD PMID:31324951 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression EXP Phenformin results in decreased expression of POR mRNA CTD PMID:31324951 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Potef POTE ankyrin domain family, member F decreases expression EXP Phenformin results in decreased expression of POTEF mRNA CTD PMID:31324951 NCBI chr18:23,626,518...23,629,132
Ensembl chr 3:72,977,767...72,979,694
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression EXP Phenformin results in decreased expression of PPARD mRNA CTD PMID:31324951 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression EXP Phenformin results in increased expression of PPCS mRNA CTD PMID:31324951 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K increases expression EXP Phenformin results in increased expression of PPM1K mRNA CTD PMID:31324951 NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:87,612,204...87,636,152
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression EXP Phenformin results in decreased expression of PPP1R15A mRNA CTD PMID:31324951 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression EXP Phenformin results in decreased expression of PPP1R3B mRNA CTD PMID:31324951 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression EXP Phenformin results in decreased expression of PRC1 mRNA CTD PMID:31324951 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression EXP Phenformin results in decreased expression of PRIM1 mRNA CTD PMID:31324951 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prox1 prospero homeobox 1 increases expression EXP Phenformin results in increased expression of PROX1 mRNA CTD PMID:31324951 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Prrg4 proline rich and Gla domain 4 decreases expression EXP Phenformin results in decreased expression of PRRG4 mRNA CTD PMID:31324951 NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP Phenformin results in increased expression of PSMB8 mRNA CTD PMID:31324951 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Ptk6 protein tyrosine kinase 6 decreases expression EXP Phenformin results in decreased expression of PTK6 mRNA CTD PMID:31324951 NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 increases expression EXP Phenformin results in increased expression of PTPN3 mRNA CTD PMID:31324951 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
JBrowse link
G Pum3-ps3 pumilio RNA-binding family member 3, pseudogene 3 increases expression EXP Phenformin results in increased expression of PUM3-PS3 mRNA CTD PMID:31324951 NCBI chr12:16,357,131...16,359,221 JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP Phenformin results in increased expression of RAB30 mRNA CTD PMID:31324951 NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 decreases expression EXP Phenformin results in decreased expression of RAPGEF5 mRNA CTD PMID:31324951 NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936
JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP Phenformin results in decreased expression of RCAN1 mRNA CTD PMID:31324951 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rdh5 retinol dehydrogenase 5 decreases expression EXP Phenformin results in decreased expression of RDH5 mRNA CTD PMID:31324951 NCBI chr 7:1,341,172...1,346,863
Ensembl chr 7:1,340,934...1,351,558
JBrowse link
G Reg3g regenerating family member 3 gamma increases expression EXP Phenformin results in increased expression of REG3G mRNA CTD PMID:31324951 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
JBrowse link
G RGD1309362 similar to interferon-inducible GTPase increases expression EXP Phenformin results in increased expression of RGD1309362 mRNA CTD PMID:31324951
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Phenformin results in decreased expression of RGS2 mRNA CTD PMID:31324951 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rp1 RP1, axonemal microtubule associated decreases expression EXP Phenformin results in decreased expression of RP1 mRNA CTD PMID:31324951 NCBI chr 5:15,121,104...15,582,363
Ensembl chr 5:15,121,133...15,579,363
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP Phenformin results in decreased expression of RRM2 mRNA CTD PMID:31324951 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G RT1-A RT1 class I, locus A decreases expression EXP Phenformin results in decreased expression of RT1-A mRNA CTD PMID:31324951
G Sbk1 SH3 domain binding kinase 1 increases expression EXP Phenformin results in increased expression of SBK1 mRNA CTD PMID:31324951 NCBI chr 1:180,807,092...180,851,910
Ensembl chr 1:180,807,099...180,851,885
JBrowse link
G Scarna15 small Cajal body-specific RNA 15 decreases expression EXP Phenformin results in decreased expression of SCARNA15 mRNA CTD PMID:31324951 NCBI chr 1:135,484,620...135,484,683
Ensembl chr 1:135,484,559...135,484,685
Ensembl chr 1:135,484,559...135,484,685
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Phenformin results in decreased expression of SCD1 mRNA CTD PMID:31324951 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sdc4 syndecan 4 decreases expression EXP Phenformin results in decreased expression of SDC4 mRNA CTD PMID:31324951 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 increases expression EXP Phenformin results in increased expression of SDR42E1 mRNA CTD PMID:31324951 NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901
JBrowse link
G Sds serine dehydratase increases expression EXP Phenformin results in increased expression of SDS mRNA CTD PMID:31324951 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP Phenformin results in increased expression of SERPINA7 mRNA CTD PMID:31324951 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Serpinc1 serpin family C member 1 increases activity ISO Phenformin results in increased activity of SERPINC1 protein CTD PMID:29458015 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Phenformin results in decreased expression of SERPINE1 mRNA CTD PMID:31324951 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression EXP Phenformin results in decreased expression of SIK1 mRNA CTD PMID:31324951 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt1 sirtuin 1 decreases expression ISO Phenformin results in decreased expression of SIRT1 protein CTD PMID:26768367 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression EXP Phenformin results in decreased expression of SLC10A2 mRNA CTD PMID:31324951 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc10a5 solute carrier family 10, member 5 decreases expression EXP Phenformin results in decreased expression of SLC10A5 mRNA CTD PMID:31324951 NCBI chr 2:91,457,540...91,458,844
Ensembl chr 2:91,444,454...91,489,651
JBrowse link
G Slc13a2 solute carrier family 13 member 2 decreases expression EXP Phenformin results in decreased expression of SLC13A2 mRNA CTD PMID:31324951 NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
JBrowse link
G Slc13a3 solute carrier family 13 member 3 increases expression EXP Phenformin results in increased expression of SLC13A3 mRNA CTD PMID:31324951 NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP Phenformin results in increased expression of SLC16A10 mRNA CTD PMID:31324951 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc17a9 solute carrier family 17 member 9 decreases expression EXP Phenformin results in decreased expression of SLC17A9 mRNA CTD PMID:31324951 NCBI chr 3:167,839,246...167,857,462
Ensembl chr 3:167,839,385...167,855,985
JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Phenformin inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Phenformin inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Phenformin results in increased expression of SLC1A2 mRNA CTD PMID:31324951 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression EXP Phenformin results in increased expression of SLC1A4 mRNA CTD PMID:31324951 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Phenformin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a23 solute carrier family 22, member 23 decreases expression EXP Phenformin results in decreased expression of SLC22A23 mRNA CTD PMID:31324951 NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790
JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases response to substance
affects uptake
ISO SLC22A4 protein results in increased susceptibility to Phenformin
SLC22A4 protein affects the uptake of Phenformin
CTD PMID:23221006 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP Phenformin results in increased expression of SLC22A5 mRNA CTD PMID:31324951 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc25a23 solute carrier family 25 member 23 decreases expression EXP Phenformin results in decreased expression of SLC25A23 mRNA CTD PMID:31324951 NCBI chr 9:1,882,636...1,898,369
Ensembl chr 9:1,882,621...1,898,561
JBrowse link
G Slc25a47 solute carrier family 25, member 47 increases expression EXP Phenformin results in increased expression of SLC25A47 mRNA CTD PMID:31324951 NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression EXP Phenformin results in increased expression of SLC27A1 mRNA CTD PMID:31324951 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a12 solute carrier family 2 member 12 increases expression EXP Phenformin results in increased expression of SLC2A12 mRNA CTD PMID:31324951 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression EXP Phenformin results in decreased expression of SLC2A5 mRNA CTD PMID:31324951 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Phenformin results in decreased expression of SLC34A2 mRNA CTD PMID:31324951 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc35c2 solute carrier family 35 member C2 decreases expression EXP Phenformin results in decreased expression of SLC35C2 mRNA CTD PMID:31324951 NCBI chr 3:154,012,262...154,023,549
Ensembl chr 3:154,012,416...154,023,488
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression EXP Phenformin results in decreased expression of SLC38A2 mRNA CTD PMID:31324951 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Phenformin inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Phenformin inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) decreases expression EXP Phenformin results in decreased expression of SLC4A1 mRNA CTD PMID:31324951 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression EXP Phenformin results in increased expression of SLC4A4 mRNA CTD PMID:31324951 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP Phenformin results in increased expression of SLC6A6 mRNA CTD PMID:31324951 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Smco1 single-pass membrane protein with coiled-coil domains 1 increases expression EXP Phenformin results in increased expression of SMCO1 mRNA CTD PMID:31324951 NCBI chr11:68,512,113...68,514,999
Ensembl chr11:68,509,150...68,515,003
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression EXP Phenformin results in increased expression of SNAI2 mRNA CTD PMID:31324951 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sntb1 syntrophin, beta 1 increases expression EXP Phenformin results in increased expression of SNTB1 mRNA CTD PMID:31324951 NCBI chr 7:87,060,926...87,329,315
Ensembl chr 7:87,060,926...87,329,315
JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression EXP Phenformin results in decreased expression of SOCS2 mRNA CTD PMID:31324951 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP Phenformin results in increased expression of SPINK1 mRNA CTD PMID:31324951 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP Phenformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Phenformin results in decreased expression of STAC3 mRNA CTD PMID:31324951 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Phenformin results in increased expression of STAT3 mRNA CTD PMID:31324951 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Phenformin results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Phenformin results in decreased expression of STMN1 mRNA CTD PMID:31324951 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stxbp6 syntaxin binding protein 6 increases expression EXP Phenformin results in increased expression of STXBP6 mRNA CTD PMID:31324951 NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024
JBrowse link
G Tbx3 T-box transcription factor 3 increases expression EXP Phenformin results in increased expression of TBX3 mRNA CTD PMID:31324951 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tcap titin-cap increases expression EXP Phenformin results in increased expression of TCAP mRNA CTD PMID:31324951 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887
JBrowse link
G Tex36 testis expressed 36 increases expression EXP Phenformin results in increased expression of TEX36 mRNA CTD PMID:31324951 NCBI chr 1:188,390,062...188,404,448
Ensembl chr 1:188,390,064...188,404,377
JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Phenformin results in increased expression of THBS1 mRNA CTD PMID:31324951 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP Phenformin results in decreased expression of THRSP mRNA CTD PMID:31324951 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tk1 thymidine kinase 1 decreases expression EXP Phenformin results in decreased expression of TK1 mRNA CTD PMID:31324951 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tkfc triokinase and FMN cyclase decreases expression EXP Phenformin results in decreased expression of TKFC mRNA CTD PMID:31324951 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP Phenformin results in increased expression of TM7SF2 mRNA CTD PMID:31324951 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
G Tmem30b transmembrane protein 30B increases expression EXP Phenformin results in increased expression of TMEM30B mRNA CTD PMID:31324951 NCBI chr 6:92,251,626...92,254,702
Ensembl chr 6:92,249,790...92,254,842
JBrowse link
G Tmem37 transmembrane protein 37 decreases expression EXP Phenformin results in decreased expression of TMEM37 mRNA CTD PMID:31324951 NCBI chr13:31,184,322...31,191,477
Ensembl chr13:31,171,355...31,191,077
JBrowse link
G Tmod4 tropomodulin 4 increases expression EXP Phenformin results in increased expression of TMOD4 mRNA CTD PMID:31324951 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression EXP Phenformin results in increased expression of TNFAIP2 mRNA CTD PMID:31324951 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression EXP Phenformin results in decreased expression of TNFAIP3 mRNA CTD PMID:31324951 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfsf13 TNF superfamily member 13 decreases expression EXP Phenformin results in decreased expression of TNFSF13 mRNA CTD PMID:31324951 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
G Tob2 transducer of ERBB2, 2 decreases expression EXP Phenformin results in decreased expression of TOB2 mRNA CTD PMID:31324951 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP Phenformin results in decreased expression of TOP2A mRNA CTD PMID:31324951 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression EXP Phenformin results in decreased expression of TP53INP1 mRNA CTD PMID:31324951 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tppp tubulin polymerization promoting protein decreases expression EXP Phenformin results in decreased expression of TPPP mRNA CTD PMID:31324951 NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression EXP Phenformin results in decreased expression of TPX2 mRNA CTD PMID:31324951 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Trim24 tripartite motif-containing 24 increases expression EXP Phenformin results in increased expression of TRIM24 mRNA CTD PMID:31324951 NCBI chr 4:66,567,342...66,692,029
Ensembl chr 4:66,566,686...66,717,241
JBrowse link
G Trim50 tripartite motif-containing 50 increases expression EXP Phenformin results in increased expression of TRIM50 mRNA CTD PMID:31324951 NCBI chr12:21,300,784...21,317,668
Ensembl chr12:21,300,785...21,317,668
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression EXP Phenformin results in decreased expression of TSC22D3 mRNA CTD PMID:31324951 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan decreases expression EXP Phenformin results in decreased expression of TSKU mRNA CTD PMID:31324951 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Tspan4 tetraspanin 4 decreases expression EXP Phenformin results in decreased expression of TSPAN4 mRNA CTD PMID:31324951 NCBI chr 1:196,571,307...196,593,842
Ensembl chr 1:196,572,228...196,617,448
JBrowse link
G Ttk Ttk protein kinase decreases expression EXP Phenformin results in decreased expression of TTK mRNA CTD PMID:31324951 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Tubb1 tubulin, beta 1 class VI decreases expression EXP Phenformin results in decreased expression of TUBB1 mRNA CTD PMID:31324951 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Phenformin results in decreased expression of TUBB2A mRNA CTD PMID:31324951 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP Phenformin results in increased expression of TXNIP mRNA CTD PMID:31324951 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP Phenformin results in decreased expression of UBE2C mRNA CTD PMID:31324951 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Phenformin results in increased expression of UCP3 mRNA CTD PMID:31324951 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression EXP Phenformin results in decreased expression of UGDH protein CTD PMID:4270849 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 increases expression EXP Phenformin results in increased expression of UGT2A3 mRNA CTD PMID:31324951 NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Phenformin results in increased expression of UGT2B1 mRNA CTD PMID:31324951 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 increases expression EXP Phenformin results in increased expression of UGT2B34L1 mRNA CTD PMID:31324951 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G Upp2 uridine phosphorylase 2 increases expression EXP Phenformin results in increased expression of UPP2 mRNA CTD PMID:31324951 NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression EXP Phenformin results in increased expression of USP18 mRNA CTD PMID:31324951 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression EXP Phenformin results in decreased expression of USP2 mRNA CTD PMID:31324951 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vgll4 vestigial-like family member 4 decreases expression EXP Phenformin results in decreased expression of VGLL4 mRNA CTD PMID:31324951 NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471
JBrowse link
G Vnn1 vanin 1 increases expression EXP Phenformin results in increased expression of VNN1 mRNA CTD PMID:31324951 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression EXP Phenformin results in decreased expression of WEE1 mRNA CTD PMID:31324951 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression EXP Phenformin results in increased expression of XIAP mRNA CTD PMID:31324951 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Ypel2 yippee-like 2 decreases expression EXP Phenformin results in decreased expression of YPEL2 mRNA CTD PMID:31324951 NCBI chr10:71,746,308...71,803,843
Ensembl chr10:71,746,311...71,803,911
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression EXP Phenformin results in decreased expression of ZBTB16 mRNA CTD PMID:31324951 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zfp354a zinc finger protein 354A decreases expression EXP Phenformin results in decreased expression of ZFP354A mRNA CTD PMID:31324951 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
JBrowse link
G Zfp36 zinc finger protein 36 decreases expression EXP Phenformin results in decreased expression of ZFP36 mRNA CTD PMID:31324951 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Znf750 zinc finger protein 750 increases expression EXP Phenformin results in increased expression of ZNF750 mRNA CTD PMID:31324951 NCBI chr10:106,772,162...106,781,186
Ensembl chr10:106,772,669...106,781,200
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        pharmaceutical 19518
          drug 19538
            antineoplastic agent 17812
              phenformin 424
Path 2
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  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            heteroorganic entity 19502
                              organonitrogen compound 18845
                                guanidines 2349
                                  biguanide 1133
                                    phenformin 424
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