Opcml (opioid binding protein/cell adhesion molecule-like) - Rat Genome Database

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Gene: Opcml (opioid binding protein/cell adhesion molecule-like) Rattus norvegicus
Analyze
Symbol: Opcml
Name: opioid binding protein/cell adhesion molecule-like
RGD ID: 620635
Description: Predicted to be involved in cell adhesion. Predicted to localize to anchored component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human OPCML (opioid binding protein/cell adhesion molecule like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: OBCAM; opioid-binding cell adhesion molecule; opioid-binding protein/cell adhesion molecule; opioid-binding protein/cell adhesion molecule-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0 Ensembl829,453,643 - 29,962,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0828,842,202 - 29,967,300 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0828,857,932 - 29,978,200 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4827,996,301 - 28,509,065 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1827,996,397 - 28,509,162 (+)NCBI
Celera828,273,156 - 28,783,272 (+)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:7891157   PMID:14596858   PMID:19943852   PMID:23376485  


Genomics

Comparative Map Data
Opcml
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0 Ensembl829,453,643 - 29,962,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0828,842,202 - 29,967,300 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0828,857,932 - 29,978,200 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4827,996,301 - 28,509,065 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1827,996,397 - 28,509,162 (+)NCBI
Celera828,273,156 - 28,783,272 (+)NCBICelera
Cytogenetic Map8q13NCBI
OPCML
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11132,414,977 - 133,532,519 (-)EnsemblGRCh38hg38GRCh38
GRCh3811132,403,361 - 133,532,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711132,284,559 - 133,402,396 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611131,790,085 - 132,907,613 (-)NCBINCBI36hg18NCBI36
Build 3411131,790,086 - 132,318,247NCBI
Celera11129,456,242 - 130,574,897 (-)NCBI
Cytogenetic Map11q25NCBI
HuRef11128,240,684 - 128,768,428 (-)NCBIHuRef
CHM1_111132,171,735 - 133,290,422 (-)NCBICHM1_1
Opcml
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39927,702,050 - 28,836,706 (+)NCBIGRCm39mm39
GRCm39 Ensembl927,702,071 - 28,836,706 (+)Ensembl
GRCm38927,790,716 - 28,925,410 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl927,790,775 - 28,925,410 (+)EnsemblGRCm38mm10GRCm38
MGSCv37927,598,854 - 28,732,643 (+)NCBIGRCm37mm9NCBIm37
MGSCv36927,540,715 - 28,674,504 (+)NCBImm8
Celera925,048,809 - 26,182,472 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map913.73NCBI
Opcml
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541233,256,352 - 34,383,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541233,256,013 - 34,385,603 (-)NCBIChiLan1.0ChiLan1.0
OPCML
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111131,117,659 - 132,246,315 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v011127,233,465 - 128,377,367 (-)NCBIMhudiblu_PPA_v0panPan3
OPCML
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.152,175,002 - 2,725,878 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl52,175,075 - 2,655,602 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha51,762,971 - 2,781,251 (+)NCBI
ROS_Cfam_1.051,600,357 - 2,620,428 (+)NCBI
UMICH_Zoey_3.151,632,492 - 2,657,700 (+)NCBI
UNSW_CanFamBas_1.051,633,356 - 2,646,280 (+)NCBI
UU_Cfam_GSD_1.051,670,829 - 2,685,911 (+)NCBI
LOC101971822
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947114,350,370 - 114,372,667 (-)NCBI
SpeTri2.0NW_00493657277,755 - 100,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPCML
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl959,037,708 - 60,140,445 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1959,037,711 - 60,141,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2965,485,634 - 65,514,812 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OPCML
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11123,446,497 - 124,617,242 (-)NCBI
ChlSab1.1 Ensembl1123,451,729 - 123,698,280 (-)Ensembl
Opcml
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248126,852,568 - 8,042,583 (-)NCBI

Position Markers
D8Rat190  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,580,453 - 29,580,579NCBIRnor6.0
Rnor_5.0829,591,143 - 29,591,269UniSTSRnor5.0
RGSC_v3.4828,124,112 - 28,124,238UniSTSRGSC3.4
RGSC_v3.4828,124,042 - 28,124,422RGDRGSC3.4
RGSC_v3.1828,124,209 - 28,124,335RGD
Celera828,400,137 - 28,400,263UniSTS
RH 3.4 Map8228.1RGD
RH 3.4 Map8228.1UniSTS
RH 2.0 Map8195.5RGD
SHRSP x BN Map818.55RGD
Cytogenetic Map8q13UniSTS
D8Rat164  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,867,983 - 29,868,170NCBIRnor6.0
Rnor_5.0829,878,681 - 29,878,868UniSTSRnor5.0
RGSC_v3.4828,414,005 - 28,414,192UniSTSRGSC3.4
RGSC_v3.4828,414,004 - 28,414,191RGDRGSC3.4
RGSC_v3.1828,414,101 - 28,414,288RGD
Celera828,688,571 - 28,688,755UniSTS
RH 3.4 Map8229.3RGD
RH 3.4 Map8229.3UniSTS
RH 2.0 Map8186.1RGD
SHRSP x BN Map818.55RGD
Cytogenetic Map8q13UniSTS
D8Got30  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,826,894 - 29,827,133NCBIRnor6.0
Rnor_5.0829,837,592 - 29,837,831UniSTSRnor5.0
RGSC_v3.4828,372,865 - 28,373,104UniSTSRGSC3.4
RGSC_v3.4828,372,864 - 28,373,104RGDRGSC3.4
RGSC_v3.1828,372,962 - 28,373,201RGD
Celera828,647,744 - 28,647,983UniSTS
RH 3.4 Map8229.3RGD
RH 3.4 Map8229.3UniSTS
RH 2.0 Map8224.1RGD
Cytogenetic Map8q13UniSTS
D8Got361  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,923,260 - 29,923,446NCBIRnor6.0
Rnor_5.0829,934,125 - 29,934,311UniSTSRnor5.0
RGSC_v3.4828,469,432 - 28,469,618UniSTSRGSC3.4
Celera828,743,760 - 28,743,918UniSTS
Cytogenetic Map8q13UniSTS
RH69042  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,961,892 - 29,962,013NCBIRnor6.0
Rnor_5.0829,972,796 - 29,972,917UniSTSRnor5.0
RGSC_v3.4828,508,143 - 28,508,264UniSTSRGSC3.4
Celera828,782,350 - 28,782,471UniSTS
Cytogenetic Map8q13UniSTS
BF410517  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,813,625 - 29,813,835NCBIRnor6.0
Rnor_5.0829,824,121 - 29,824,331UniSTSRnor5.0
RGSC_v3.4828,358,971 - 28,359,181UniSTSRGSC3.4
Celera828,634,473 - 28,634,683UniSTS
RH 3.4 Map8230.6UniSTS
Cytogenetic Map8q13UniSTS
BF405647  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,783,313 - 29,783,417NCBIRnor6.0
Rnor_5.0829,793,809 - 29,793,913UniSTSRnor5.0
RGSC_v3.4828,328,619 - 28,328,723UniSTSRGSC3.4
Celera828,604,030 - 28,604,134UniSTS
RH 3.4 Map8228.0UniSTS
Cytogenetic Map8q13UniSTS
G45150  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0829,783,485 - 29,783,726NCBIRnor6.0
Rnor_5.0829,793,981 - 29,794,222UniSTSRnor5.0
RGSC_v3.4828,328,791 - 28,329,032UniSTSRGSC3.4
Celera828,604,202 - 28,604,443UniSTS
Cytogenetic Map8q13UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8210812847108128Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8210812847108128Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8210812847108128Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8210812847108128Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8736807652368076Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8736807652368076Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8736807652368076Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8873867753738677Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)89531047119211942Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)81038843955388439Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)81038843955388439Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810938911120496129Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81137326757541668Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81137350945712344Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81137350945712344Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81144825156448251Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81144825156448251Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81766655562666555Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)82071759265717592Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)82146491991140553Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)821813070100873963Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82784149672841496Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82816802350708951Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82986798359908353Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)829867983106526740Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)829867983106526740Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)829867983106526740Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:96
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000042890
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 10 62 6
Low 1 43 16 12 3 12 7 7 12 29 28 11 7
Below cutoff 2 39 27 6 27 1 4 11 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000042890   ⟹   ENSRNOP00000044106
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl829,714,285 - 29,962,825 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090643   ⟹   ENSRNOP00000073684
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl829,453,643 - 29,961,975 (+)Ensembl
RefSeq Acc Id: NM_053848   ⟹   NP_446300
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2826,789,668 - 27,300,065 (+)NCBI
Rnor_6.0829,453,178 - 29,962,814 (+)NCBI
Rnor_5.0828,857,932 - 29,978,200 (+)NCBI
RGSC_v3.4827,996,301 - 28,509,065 (+)RGD
Celera828,273,156 - 28,783,272 (+)RGD
Sequence:
RefSeq Acc Id: XM_017595412   ⟹   XP_017450901
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595413   ⟹   XP_017450902
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595414   ⟹   XP_017450903
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0828,842,203 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595415   ⟹   XP_017450904
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595416   ⟹   XP_017450905
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0828,842,202 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595417   ⟹   XP_017450906
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0829,253,084 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595418   ⟹   XP_017450907
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_446300   ⟸   NM_053848
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: XP_017450905   ⟸   XM_017595416
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017450903   ⟸   XM_017595414
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017450906   ⟸   XM_017595417
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017450901   ⟸   XM_017595412
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017450902   ⟸   XM_017595413
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017450904   ⟸   XM_017595415
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017450907   ⟸   XM_017595418
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000073684   ⟸   ENSRNOT00000090643
RefSeq Acc Id: ENSRNOP00000044106   ⟸   ENSRNOT00000042890
Protein Domains
Ig-like   Ig-like C2-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620635 AgrOrtholog
Ensembl Genes ENSRNOG00000023809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000044106 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073684 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042890 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000090643 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116597 UniProtKB/Swiss-Prot
NCBI Gene 116597 ENTREZGENE
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Opcml PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K657_RAT UniProtKB/TrEMBL
  F1M2I5_RAT UniProtKB/TrEMBL
  OPCM_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P32735 UniProtKB/Swiss-Prot
  Q01653 UniProtKB/Swiss-Prot
  Q01654 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Opcml  opioid binding protein/cell adhesion molecule-like    opioid-binding protein/cell adhesion molecule-like  Name updated 1299863 APPROVED
2005-01-20 Opcml  opioid-binding protein/cell adhesion molecule-like      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Opcml  opioid-binding protein/cell adhesion molecule-like      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology identical to OBCAM in its C-terminal 318 amino acids 727538