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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bexarotene
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Accession:CHEBI:50859 term browser browse the term
Definition:A retinoid that has formula C24H28O2.
Synonyms:exact_synonym: 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
 related_synonym: Formula=C24H28O2;   InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26);   InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N;   SMILES=Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C;   bexaroteno;   bexarotenum;   p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid
 xref: CAS:153559-49-0;   DrugBank:DB00307;   Drug_Central:361;   KEGG:D03106
 xref_mesh: MESH:C095105
 xref: Patent:US5466861;   Patent:WO9321146;   Wikipedia:Bexarotene


show annotations for term's descendants           Sort by:
bexarotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of A1BG mRNA CTD PMID:17630414 NCBI chr15:60,789,438...60,793,119
Ensembl chr15:60,768,708...60,794,861 		JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 increases expression
multiple interactions
increases expression 		EXP
ISO		 bexarotene results in increased expression of ABCA1; bexarotene results in increased expression of ABCA1 mRNA
diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of ABCA1 mRNA]
[bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein
bexarotene increases expression of Abca1 protein in mouse cerebral cortex
bexarotene increases expression of abca1 protein in mouse hippocampus		 CTD
RGD		 PMID:21622945 PMID:25932594 PMID:26688581 PMID:25217640 RGD:11056803, RGD:21408550 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 increases expression ISO bexarotene results in increased expression of ABCB11 mRNA CTD PMID:16648578 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcd3 ATP-binding cassette, sub-family D member 3 increases expression ISO bexarotene results in increased expression of ABCD3 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr 3:121,552,553...121,609,851
Ensembl chr 3:121,552,423...121,608,951 		JBrowse link
G Acaa1a acetyl-Coenzyme A acyltransferase 1A increases expression
multiple interactions		 ISO bexarotene results in increased expression of ACAA1 mRNA; bexarotene results in increased expression of ACAA1A mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of ACAA1 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 9:119,170,113...119,179,361
Ensembl chr 9:119,168,742...119,179,365 		JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases expression ISO bexarotene results in increased expression of ACACA mRNA CTD PMID:23292798 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477 		JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain increases expression ISO bexarotene results in increased expression of ACADM mRNA CTD PMID:23292798 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269 		JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 increases expression
multiple interactions		 ISO bexarotene results in increased expression of ACAT1 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of ACAT1 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
G Ache acetylcholinesterase decreases expression ISO bexarotene results in decreased expression of ACHE mRNA CTD PMID:16648578 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression
multiple interactions		 ISO Bexarotene results in increased expression of ACOT1 mRNA
[Tamoxifen co-treated with Bexarotene] results in increased expression of ACOT1 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr12:84,056,276...84,064,444
Ensembl chr12:84,056,264...84,065,145 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO bexarotene results in increased expression of ACOT2 mRNA CTD PMID:16648578 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases expression ISO bexarotene results in increased expression of ACOX1 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression ISO bexarotene results in increased expression of ACSL1 mRNA CTD PMID:23292798 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO bexarotene results in increased expression of ACSL5 mRNA CTD PMID:23292798 NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of SAH mRNA CTD PMID:17630414 NCBI chr 7:119,360,106...119,384,119
Ensembl chr 7:119,360,146...119,386,736 		JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta increases expression ISO bexarotene results in increased expression of ACTA2 mRNA CTD PMID:16648578 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression ISO bexarotene results in increased expression of ACTC1 mRNA CTD PMID:16648578 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029 		JBrowse link
G Actg1 actin, gamma, cytoplasmic 1 increases expression ISO bexarotene results in increased expression of ACTG1 mRNA CTD PMID:16648578 NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368 		JBrowse link
G Acvr2b activin receptor IIB increases expression ISO bexarotene results in increased expression of ACVR2B mRNA CTD PMID:16648578 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061 		JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression ISO bexarotene results in decreased expression of ADCY6 mRNA CTD PMID:16648578 NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957 		JBrowse link
G Add3 adducin 3 increases expression ISO bexarotene results in increased expression of ADD3 mRNA CTD PMID:17178900 NCBI chr19:53,128,874...53,235,518
Ensembl chr19:53,128,874...53,235,830 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression ISO bexarotene results in increased expression of ADH4 mRNA CTD PMID:17630414 NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653 		JBrowse link
G Adig adipogenin multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of ADIG mRNA CTD PMID:17630414 NCBI chr 2:158,344,532...158,350,118
Ensembl chr 2:158,344,532...158,350,118 		JBrowse link
G Adra1b adrenergic receptor, alpha 1b decreases expression ISO bexarotene results in decreased expression of ADRA1B mRNA CTD PMID:16648578 NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 decreases expression ISO bexarotene results in decreased expression of ADRB2 mRNA CTD PMID:17178900 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Agxt alanine-glyoxylate aminotransferase increases expression ISO bexarotene results in increased expression of AGXT mRNA CTD PMID:16648578 NCBI chr 1:93,062,962...93,073,143
Ensembl chr 1:93,062,962...93,073,143 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO bexarotene results in decreased expression of AHSG mRNA CTD PMID:16648578 NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199 		JBrowse link
G Akap12 A kinase anchor protein 12 increases expression ISO bexarotene results in increased expression of AKAP12 mRNA CTD PMID:16648578 NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470 		JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 increases expression ISO bexarotene results in increased expression of AKR1C3 mRNA CTD PMID:17178900 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 decreases expression ISO bexarotene results in decreased expression of ALDH3A2 mRNA CTD PMID:16648578 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290 		JBrowse link
G Aldob aldolase B, fructose-bisphosphate decreases expression ISO bexarotene results in decreased expression of ALDOB mRNA CTD PMID:16648578 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546 		JBrowse link
G Aldoc aldolase C, fructose-bisphosphate increases expression ISO bexarotene results in increased expression of ALDOC mRNA CTD PMID:16648578 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607 		JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney increases expression ISO bexarotene results in increased expression of ALPL mRNA CTD PMID:16648578 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695 		JBrowse link
G Amotl2 angiomotin-like 2 decreases expression ISO bexarotene results in decreased expression of AMOTL2 mRNA CTD PMID:17178900 NCBI chr 9:102,594,290...102,610,616
Ensembl chr 9:102,593,871...102,610,617 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP bexarotene results in increased expression of ANGPTL4 mRNA CTD PMID:21622945 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804 		JBrowse link
G Ank3 ankyrin 3, epithelial decreases expression ISO bexarotene results in decreased expression of ANK3 mRNA CTD PMID:16648578 NCBI chr10:69,234,608...69,863,266
Ensembl chr10:69,234,603...69,863,268 		JBrowse link
G Anxa3 annexin A3 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of ANXA3 mRNA CTD PMID:17630414 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825 		JBrowse link
G Aplp2 amyloid beta precursor-like protein 2 increases expression ISO bexarotene results in increased expression of APLP2 mRNA CTD PMID:16648578 NCBI chr 9:31,060,853...31,123,144
Ensembl chr 9:31,060,853...31,123,111 		JBrowse link
G Apoa2 apolipoprotein A-II multiple interactions
decreases expression
increases expression		 ISO RXRA promotes the reaction [bexarotene results in increased expression of APOA2 mRNA]
bexarotene results in decreased expression of APOA2 mRNA		 CTD PMID:8668150 PMID:16648578 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Apob apolipoprotein B decreases expression ISO bexarotene results in decreased expression of APOB mRNA CTD PMID:16648578 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Apoc1 apolipoprotein C-I decreases expression ISO bexarotene results in decreased expression of APOC1 mRNA CTD PMID:16648578 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoc3 apolipoprotein C-III decreases expression ISO bexarotene results in decreased expression of APOC3 mRNA CTD PMID:16648578 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Apod apolipoprotein D increases expression EXP bexarotene results in increased expression of APOD mRNA CTD PMID:17849452 NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626 		JBrowse link
G App amyloid beta precursor protein increases expression ISO bexarotene results in increased expression of APP mRNA CTD PMID:16648578 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Aqp7 aquaporin 7 multiple interactions
decreases expression		 ISO [bexarotene co-treated with Tamoxifen] results in increased expression of AQP7 mRNA
bexarotene results in decreased expression of AQP7 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139 		JBrowse link
G Ar androgen receptor multiple interactions
increases expression		 ISO bexarotene binds to and results in decreased activity of AR protein
bexarotene results in increased expression of AR mRNA		 CTD PMID:16648578 PMID:25752796 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Arf1 ARF GTPase 1 increases expression ISO bexarotene results in increased expression of ARF1 mRNA CTD PMID:16648578 NCBI chr11:59,102,237...59,119,042
Ensembl chr11:59,102,238...59,119,096 		JBrowse link
G Arg1 arginase, liver decreases expression ISO bexarotene results in decreased expression of ARG1 mRNA CTD PMID:16648578 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 increases expression ISO bexarotene results in increased expression of ARL6IP5 mRNA CTD PMID:17178900 NCBI chr 6:97,187,753...97,210,276
Ensembl chr 6:97,187,650...97,210,276 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression ISO bexarotene results in increased expression of ARPC1B mRNA CTD PMID:16648578 NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of ASCL1 mRNA CTD PMID:17630414 NCBI chr10:87,326,681...87,329,522
Ensembl chr10:87,326,681...87,329,522 		JBrowse link
G Asgr1 asialoglycoprotein receptor 1 increases expression ISO bexarotene results in increased expression of ASGR1 mRNA CTD PMID:16648578 NCBI chr11:69,939,735...69,948,721
Ensembl chr11:69,944,911...69,948,720 		JBrowse link
G Asns asparagine synthetase decreases expression ISO bexarotene results in decreased expression of ASNS mRNA CTD PMID:17178900 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254 		JBrowse link
G Atm ataxia telangiectasia mutated increases activity ISO bexarotene results in increased activity of ATM protein CTD PMID:19067706 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide increases expression ISO bexarotene results in increased expression of ATP1A1 mRNA CTD PMID:16648578 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000 		JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide decreases expression ISO bexarotene results in decreased expression of ATP1B1 mRNA CTD PMID:16648578 NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924 		JBrowse link
G Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide increases expression ISO bexarotene results in increased expression of ATP4A mRNA CTD PMID:16648578 NCBI chr 7:30,411,634...30,424,959
Ensembl chr 7:30,411,634...30,424,959 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression ISO bexarotene results in increased expression of ATP5F1D mRNA CTD PMID:16648578 NCBI chr10:79,974,451...79,981,662
Ensembl chr10:79,974,466...79,981,652 		JBrowse link
G Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C increases expression ISO bexarotene results in increased expression of ATP6V0C mRNA CTD PMID:16648578 NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO bexarotene results in increased expression of and results in increased activity of BAX protein CTD PMID:19067706 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of BBS2 mRNA CTD PMID:17630414 NCBI chr 8:94,794,580...94,825,997
Ensembl chr 8:94,794,582...94,825,556 		JBrowse link
G Bglap bone gamma carboxyglutamate protein multiple interactions ISO bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:25932594 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression ISO bexarotene results in decreased expression of BHLHE41 mRNA CTD PMID:16648578 NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP
ISO		 bexarotene results in decreased expression of BIRC5 mRNA
bexarotene results in decreased expression of BIRC5 protein		 CTD PMID:17849452 PMID:19067706 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of BMP2 mRNA CTD PMID:17630414 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Bnip2 BCL2/adenovirus E1B interacting protein 2 decreases expression ISO bexarotene results in decreased expression of BNIP2 mRNA CTD PMID:17178900 NCBI chr 9:69,896,660...69,918,941
Ensembl chr 9:69,896,748...69,915,599 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression ISO bexarotene results in decreased expression of BTG2 mRNA CTD PMID:16648578 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858 		JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide multiple interactions
increases expression		 ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of C1QB mRNA
bexarotene results in increased expression of C1QB mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498 		JBrowse link
G C3 complement component 3 decreases expression ISO bexarotene results in decreased expression of C3 mRNA CTD PMID:16648578 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of CACNA2D3 mRNA CTD PMID:17630414 NCBI chr14:28,626,900...29,444,732
Ensembl chr14:28,626,900...29,443,821 		JBrowse link
G Calr calreticulin increases expression ISO bexarotene results in increased expression of CALR mRNA CTD PMID:16648578 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO bexarotene results in increased expression of CAMK2G mRNA CTD PMID:16648578 NCBI chr14:20,784,943...20,844,225
Ensembl chr14:20,784,943...20,844,156 		JBrowse link
G Canx calnexin increases expression ISO bexarotene results in increased expression of CANX mRNA CTD PMID:16648578 NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500 		JBrowse link
G Casp3 caspase 3 decreases expression EXP bexarotene results in decreased expression of CASP3 mRNA CTD PMID:17849452 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp6 caspase 6 decreases expression ISO Bexarotene results in decreased expression of CASP6 mRNA CTD PMID:16648578 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752 		JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO Bexarotene results in increased expression of CBR1 mRNA CTD PMID:16648578 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases expression ISO bexarotene results in decreased expression of CCL11 mRNA CTD PMID:16648578 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO Bexarotene results in decreased expression of CCN1 mRNA CTD PMID:17178900 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO bexarotene results in decreased expression of CCNB1 protein CTD PMID:19067706 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP bexarotene results in decreased expression of CCNB2 mRNA CTD PMID:17849452 NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829 		JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
multiple interactions		 ISO
EXP		 bexarotene results in increased expression of CCND1 mRNA
bexarotene results in decreased expression of CCND1 mRNA
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 protein]; Bexarotene affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; Bexarotene affects the reaction [Azoxymethane affects the expression of CCND1 protein]		 CTD PMID:16648578 PMID:17178900 PMID:24080207 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccne1 cyclin E1 decreases expression EXP bexarotene results in decreased expression of CCNE1 mRNA CTD PMID:17849452 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959 		JBrowse link
G Cd14 CD14 antigen increases expression ISO bexarotene results in increased expression of CD14 mRNA CTD PMID:16648578 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd36 CD36 molecule increases expression ISO bexarotene results in increased expression of CD36 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd37 CD37 antigen increases expression ISO bexarotene results in increased expression of CD37 mRNA CTD PMID:16648578 NCBI chr 7:44,883,056...44,888,701
Ensembl chr 7:44,883,056...44,888,539 		JBrowse link
G Cd48 CD48 antigen multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CD48 mRNA CTD PMID:17630414 NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826 		JBrowse link
G Cd5l CD5 antigen-like multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CD5L mRNA CTD PMID:17630414 NCBI chr 3:87,265,188...87,278,381
Ensembl chr 3:87,265,188...87,278,380 		JBrowse link
G Cd68 CD68 antigen multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CD68 mRNA CTD PMID:17630414 NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) increases expression ISO bexarotene results in increased expression of CD74 mRNA CTD PMID:16648578 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Cdc37 cell division cycle 37 increases expression ISO bexarotene results in increased expression of CDC37 mRNA CTD PMID:16648578 NCBI chr 9:21,050,727...21,061,230
Ensembl chr 9:21,044,518...21,061,278 		JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases expression ISO bexarotene results in decreased expression of CDK1 protein CTD PMID:19067706 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDK2 protein] CTD PMID:24080207 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO bexarotene results in increased expression of CDKN1A protein
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDKN1A protein]; Bexarotene affects the reaction [Azoxymethane affects the expression of CDKN1A protein]		 CTD PMID:19067706 PMID:24080207 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdo1 cysteine dioxygenase 1, cytosolic decreases expression ISO bexarotene results in decreased expression of CDO1 mRNA CTD PMID:16648578 NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO bexarotene results in decreased expression of CEBPG mRNA CTD PMID:17178900 NCBI chr 7:34,745,847...34,755,991
Ensembl chr 7:34,745,847...34,755,998 		JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions		 ISO bexarotene results in increased expression of CES2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of CES2 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Cfd complement factor D multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CFD mRNA CTD PMID:17630414 NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit increases expression ISO bexarotene results in increased expression of CHRNA2 mRNA CTD PMID:16648578 PMID:17630414 NCBI chr14:66,370,685...66,390,397
Ensembl chr14:66,372,488...66,390,397 		JBrowse link
G Ciao1 cytosolic iron-sulfur protein assembly 1 decreases expression ISO bexarotene results in decreased expression of CIAO1 mRNA CTD PMID:16648578 NCBI chr 2:127,082,858...127,089,736
Ensembl chr 2:127,082,858...127,089,736 		JBrowse link
G Cimap1b ciliary microtubule associated protein 1B multiple interactions ISO [Bexarotene co-treated with Tamoxifen] results in increased expression of CIMAP1B mRNA CTD PMID:17630414 NCBI chr15:89,261,652...89,263,817
Ensembl chr15:89,261,652...89,263,790 		JBrowse link
G Ckb creatine kinase, brain increases expression ISO bexarotene results in increased expression of CKB mRNA CTD PMID:16648578 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772 		JBrowse link
G Cldn3 claudin 3 increases expression ISO bexarotene results in increased expression of CLDN3 mRNA CTD PMID:16648578 NCBI chr 5:135,015,068...135,016,330
Ensembl chr 5:135,015,068...135,016,326 		JBrowse link
G Cldn7 claudin 7 increases expression ISO bexarotene results in increased expression of CLDN7 mRNA CTD PMID:16648578 NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711 		JBrowse link
G Col12a1 collagen, type XII, alpha 1 decreases expression ISO bexarotene results in decreased expression of COL12A1 mRNA CTD PMID:16648578 NCBI chr 9:79,506,269...79,628,423
Ensembl chr 9:79,506,273...79,626,113 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression ISO bexarotene results in increased expression of COLQ mRNA CTD PMID:16648578 NCBI chr14:31,245,039...31,299,820
Ensembl chr14:31,245,039...31,313,300 		JBrowse link
G Comt catechol-O-methyltransferase decreases expression
increases expression		 ISO bexarotene results in decreased expression of COMT mRNA
bexarotene results in increased expression of COMT mRNA		 CTD PMID:16648578 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
G Coro1b coronin, actin binding protein 1B increases expression ISO bexarotene results in increased expression of CORO1B mRNA CTD PMID:16648578 NCBI chr19:4,198,610...4,204,034
Ensembl chr19:4,198,618...4,204,034 		JBrowse link
G Cpa1 carboxypeptidase A1, pancreatic multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CPA1 mRNA CTD PMID:17630414 NCBI chr 6:30,639,217...30,645,360
Ensembl chr 6:30,639,217...30,645,362 		JBrowse link
G Cps1 carbamoyl-phosphate synthetase 1 decreases expression ISO bexarotene results in decreased expression of CPS1 mRNA CTD PMID:16648578 NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1b, muscle multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of CPT1B mRNA CTD PMID:17630414 NCBI chr15:89,300,608...89,310,065
Ensembl chr15:89,300,608...89,310,066 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression ISO bexarotene results in increased expression of CPT2 mRNA CTD PMID:16648578 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807 		JBrowse link
G Crot carnitine O-octanoyltransferase increases expression ISO bexarotene results in increased expression of CROT mRNA CTD PMID:16648578 NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CSF1R mRNA CTD PMID:17630414 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 increases expression ISO bexarotene results in increased expression of CSPG5 mRNA CTD PMID:16648578 NCBI chr 9:110,072,851...110,091,644
Ensembl chr 9:110,072,851...110,091,644 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO bexarotene results in decreased expression of CSRP2 mRNA CTD PMID:16648578 NCBI chr10:110,756,037...110,775,375
Ensembl chr10:110,755,650...110,775,483 		JBrowse link
G Cth cystathionine gamma lyase decreases expression ISO bexarotene results in decreased expression of CTH mRNA CTD PMID:17178900 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 protein]; Bexarotene affects the reaction [Azoxymethane affects the expression of CTNNB1 mRNA]; Bexarotene affects the reaction [Azoxymethane affects the expression of CTNNB1 protein] CTD PMID:24080207 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Ctrc chymotrypsin C increases expression ISO bexarotene results in increased expression of CTRC mRNA CTD PMID:16648578 NCBI chr 4:141,565,550...141,573,598
Ensembl chr 4:141,565,550...141,573,670 		JBrowse link
G Ctsh cathepsin H increases expression ISO bexarotene results in increased expression of CTSH mRNA CTD PMID:17178900 NCBI chr 9:89,936,320...89,958,148
Ensembl chr 9:89,936,205...89,958,142 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CXCL1 mRNA CTD PMID:17630414 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO bexarotene results in decreased expression of CXCL14 mRNA CTD PMID:16648578 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO bexarotene results in decreased expression of CXCL3 mRNA CTD PMID:16648578 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) decreases expression ISO bexarotene results in decreased expression of CYB5A mRNA CTD PMID:16648578 NCBI chr18:84,869,463...84,897,996
Ensembl chr18:84,856,829...84,897,996 		JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO bexarotene results in decreased expression of CYCS mRNA CTD PMID:17178900 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of CYP17A1 mRNA CTD PMID:17630414 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression ISO bexarotene results in decreased expression of CYP1A2 mRNA CTD PMID:16648578 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO bexarotene results in increased expression of CYP1B1 mRNA CTD PMID:16648578 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO bexarotene results in increased expression of CYP26A1 mRNA
[bexarotene co-treated with Tamoxifen] results in increased expression of CYP26A1 mRNA		 CTD PMID:17178900 PMID:17630414 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression EXP bexarotene results in increased expression of CYP26B1 mRNA CTD PMID:17849452 NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO bexarotene results in increased expression of CYP27A1 mRNA CTD PMID:16648578 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051 		JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of CYP2A1 mRNA CTD PMID:17630414 NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression		 ISO RXRA protein affects the reaction [Bexarotene results in increased expression of CYP2B6 mRNA] CTD PMID:31312845 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression ISO bexarotene results in increased expression of CYP2B2 mRNA CTD PMID:16648578 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B increases expression ISO bexarotene results in increased expression of CYP4A22 mRNA CTD PMID:16648578 NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231 		JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 decreases expression ISO bexarotene results in decreased expression of CYP4F1 mRNA CTD PMID:16648578 NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316 		JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of CYP8B1 mRNA CTD PMID:17630414 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371 		JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein decreases expression ISO Bexarotene results in decreased expression of DAB2 mRNA CTD PMID:16648578 NCBI chr15:6,329,269...6,470,196
Ensembl chr15:6,329,269...6,470,193 		JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 increases expression ISO bexarotene results in increased expression of DACT2 mRNA CTD PMID:17630414 NCBI chr17:14,415,492...14,424,595
Ensembl chr17:14,415,314...14,424,566 		JBrowse link
G Dapk3 death-associated protein kinase 3 decreases expression ISO bexarotene results in decreased expression of DAPK3 mRNA CTD PMID:16648578 NCBI chr10:81,018,821...81,029,031
Ensembl chr10:81,018,839...81,029,031 		JBrowse link
G Dbp D site albumin promoter binding protein decreases expression ISO bexarotene results in decreased expression of DBP mRNA CTD PMID:16648578 NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO bexarotene results in decreased expression of DDIT3 mRNA CTD PMID:16648578 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO bexarotene results in increased expression of DDIT4 mRNA CTD PMID:17178900 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656 		JBrowse link
G Decr2 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal increases expression ISO bexarotene results in increased expression of DECR2 mRNA CTD PMID:16648578 NCBI chr17:26,300,182...26,309,096
Ensembl chr17:26,300,182...26,309,311 		JBrowse link
G Depp1 DEPP1 autophagy regulator increases expression ISO bexarotene results in increased expression of DEPP1 mRNA CTD PMID:17178900 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO bexarotene results in increased expression of DHCR7 mRNA CTD PMID:16648578 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO bexarotene results in increased expression of DHRS3 mRNA CTD PMID:17178900 NCBI chr 4:144,618,712...144,654,214
Ensembl chr 4:144,619,397...144,654,779 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO bexarotene results in increased expression of DKK1 mRNA CTD PMID:17178900 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression ISO bexarotene results in increased expression of DLAT mRNA CTD PMID:16648578 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080 		JBrowse link
G Dmp1 dentin matrix protein 1 multiple interactions ISO bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA] CTD PMID:25932594 NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO bexarotene results in decreased expression of DNAJA1 mRNA CTD PMID:16648578 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149 		JBrowse link
G Dnmt3a DNA methyltransferase 3A decreases expression EXP bexarotene results in decreased expression of DNMT3A mRNA CTD PMID:17849452 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO bexarotene results in decreased expression of DUSP1 mRNA CTD PMID:16648578 PMID:17178900 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression ISO bexarotene results in decreased expression of DUSP5 mRNA CTD PMID:17178900 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862 		JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 decreases expression ISO bexarotene results in decreased expression of DYNC1I2 mRNA CTD PMID:16648578 NCBI chr 2:71,041,999...71,093,647
Ensembl chr 2:71,042,050...71,093,647 		JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal increases expression ISO bexarotene results in increased expression of ECH1 mRNA CTD PMID:23292798 NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672 		JBrowse link
G Echdc1 enoyl Coenzyme A hydratase domain containing 1 increases expression ISO bexarotene results in increased expression of ECHDC1 mRNA CTD PMID:23292798 NCBI chr10:29,174,140...29,222,657
Ensembl chr10:29,189,162...29,223,465 		JBrowse link
G Eci1 enoyl-Coenzyme A delta isomerase 1 increases expression ISO bexarotene results in increased expression of ECI1 mRNA CTD PMID:16648578 NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322 		JBrowse link
G Ednrb endothelin receptor type B increases expression ISO bexarotene results in increased expression of EDNRB mRNA CTD PMID:16648578 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Egf epidermal growth factor increases expression ISO bexarotene results in increased expression of EGF mRNA CTD PMID:16648578 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of EGR1 mRNA CTD PMID:17630414 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Egr3 early growth response 3 decreases expression ISO bexarotene results in decreased expression of EGR3 mRNA CTD PMID:17178900 NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063 		JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase multiple interactions
increases expression		 ISO [Tamoxifen co-treated with bexarotene] results in increased expression of EHHADH mRNA
bexarotene results in increased expression of EHHADH mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO bexarotene results in decreased expression of EIF1 mRNA CTD PMID:17178900 NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO bexarotene results in decreased expression of EIF3C mRNA CTD PMID:17630414 NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of ELOVL6 mRNA CTD PMID:17630414 NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144 		JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression ISO bexarotene results in increased expression of ENO1 mRNA CTD PMID:16648578 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO bexarotene results in decreased expression of ENPP2 mRNA CTD PMID:16648578 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288 		JBrowse link
G Epha2 Eph receptor A2 decreases expression ISO bexarotene results in decreased expression of EPHA2 mRNA CTD PMID:17178900 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695 		JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression ISO bexarotene results in increased expression of EPHX1 mRNA CTD PMID:23292798 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic increases expression ISO bexarotene results in increased expression of EPHX2 mRNA CTD PMID:23292798 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO bexarotene results in increased expression of ERP29 mRNA CTD PMID:16648578 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression EXP bexarotene results in decreased expression of ESR1 mRNA CTD PMID:17849452 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO bexarotene binds to and results in decreased activity of ESR2 protein
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 protein]; Bexarotene affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; Bexarotene affects the reaction [Azoxymethane affects the expression of ESR2 protein]		 CTD PMID:24080207 PMID:25752796 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G F2 coagulation factor II decreases expression ISO bexarotene results in decreased expression of F2 mRNA CTD PMID:16648578 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fabp1 fatty acid binding protein 1, liver decreases expression ISO bexarotene results in decreased expression of FABP1 mRNA CTD PMID:16648578 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007 		JBrowse link
G Fabp2 fatty acid binding protein 2, intestinal decreases expression
multiple interactions		 ISO bexarotene results in decreased expression of FABP2 mRNA
[Tamoxifen co-treated with bexarotene] results in decreased expression of FABP2 mRNA		 CTD PMID:17630414 NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155 		JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of FABP3 mRNA CTD PMID:17630414 NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256 		JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression EXP bexarotene results in increased expression of FABP4 mRNA; bexarotene results in increased expression of FABP4 protein CTD PMID:21622945 PMID:25932594 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636 		JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions		 ISO bexarotene results in increased expression of FADS2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of FADS2 mRNA		 CTD PMID:17630414 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110 		JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO bexarotene results in decreased expression of FAM13A mRNA CTD PMID:17630414 NCBI chr 6:58,910,521...59,001,487
Ensembl chr 6:58,909,075...59,001,534 		JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression		 ISO [Tamoxifen co-treated with bexarotene] results in increased expression of FASN mRNA
bexarotene results in increased expression of FASN mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of FASN mRNA; [Bexarotene co-treated with paxilline] results in increased expression of FASN mRNA; [Bexarotene co-treated with T0901317] results in increased expression of FASN mRNA		 CTD PMID:16648578 PMID:17630414 PMID:32123961 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of FCGR2B mRNA CTD PMID:17630414 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of FCGR3 mRNA CTD PMID:17630414 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO bexarotene results in increased expression of FDFT1 mRNA CTD PMID:16648578 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027 		JBrowse link
G Fga fibrinogen alpha chain decreases expression ISO bexarotene results in decreased expression of FGA mRNA CTD PMID:16648578 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fgb fibrinogen beta chain decreases expression ISO bexarotene results in decreased expression of FGB mRNA CTD PMID:16648578 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170 		JBrowse link
G Fgg fibrinogen gamma chain decreases expression ISO bexarotene results in decreased expression of FGG mRNA CTD PMID:16648578 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Fh1 fumarate hydratase 1 decreases expression ISO bexarotene results in decreased expression of FH1 mRNA CTD PMID:16648578 NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201 		JBrowse link
G Fmo1 flavin containing monooxygenase 1 decreases expression ISO bexarotene results in decreased expression of FMO1 mRNA CTD PMID:16648578 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO bexarotene results in increased expression of FN1 mRNA CTD PMID:16648578 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Foxa1 forkhead box A1 increases expression ISO bexarotene results in increased expression of FOXA1 mRNA CTD PMID:16648578 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702 		JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO bexarotene results in decreased expression of FOXA2 mRNA CTD PMID:16648578 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889 		JBrowse link
G Galr2 galanin receptor 2 increases expression ISO bexarotene results in increased expression of GALR2 mRNA CTD PMID:16648578 NCBI chr11:116,170,520...116,174,776
Ensembl chr11:116,171,765...116,174,764 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 decreases expression ISO Bexarotene results in decreased expression of GARS1 mRNA CTD PMID:17178900 NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485 		JBrowse link
G Gas6 growth arrest specific 6 decreases expression
multiple interactions		 ISO bexarotene results in decreased expression of GAS6 mRNA
[bexarotene co-treated with Tamoxifen] results in decreased expression of GAS6 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490 		JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO bexarotene results in increased expression of GAS7 mRNA CTD PMID:16648578 NCBI chr11:67,344,083...67,579,818
Ensembl chr11:67,345,917...67,575,800 		JBrowse link
G Gc vitamin D binding protein decreases expression ISO bexarotene results in decreased expression of GC mRNA CTD PMID:16648578 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Gcgr glucagon receptor decreases expression ISO bexarotene results in decreased expression of GCGR mRNA CTD PMID:16648578 NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812 		JBrowse link
G Ghrh growth hormone releasing hormone increases expression ISO bexarotene results in increased expression of GHRH mRNA CTD PMID:16648578 NCBI chr 2:157,171,416...157,190,645
Ensembl chr 2:157,171,417...157,189,426 		JBrowse link
G Glra3 glycine receptor, alpha 3 subunit increases expression ISO bexarotene results in increased expression of GLRA3 mRNA CTD PMID:16648578 NCBI chr 8:56,393,454...56,583,111
Ensembl chr 8:56,393,495...56,583,105 		JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 increases expression ISO bexarotene results in increased expression of GOSR1 mRNA CTD PMID:16648578 NCBI chr11:76,617,428...76,654,404
Ensembl chr11:76,617,428...76,654,405 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) increases expression ISO bexarotene results in increased expression of GPD1 mRNA CTD PMID:23292798 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886 		JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of GPD2 mRNA CTD PMID:17630414 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731 		JBrowse link
G Gpm6a glycoprotein m6a multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of GPM6A mRNA CTD PMID:17630414 NCBI chr 8:55,232,469...55,513,913
Ensembl chr 8:55,407,878...55,513,906 		JBrowse link
G Gpm6b glycoprotein m6b increases expression ISO bexarotene results in increased expression of GPM6B mRNA CTD PMID:17178900 NCBI chr  X:165,021,911...165,172,028
Ensembl chr  X:165,021,907...165,171,984 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO bexarotene results in increased expression of GPX4 mRNA CTD PMID:16648578 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) increases expression ISO bexarotene results in increased expression of GRIN2C mRNA CTD PMID:17630414 NCBI chr11:115,139,995...115,158,123
Ensembl chr11:115,139,995...115,158,069 		JBrowse link
G Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) increases expression ISO bexarotene results in increased expression of GRINA mRNA CTD PMID:16648578 NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases expression ISO bexarotene results in increased expression of GRK2 mRNA CTD PMID:16648578 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) increases expression ISO bexarotene results in increased expression of GSTA5 mRNA CTD PMID:23292798 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966 		JBrowse link
G Gys2 glycogen synthase 2 decreases expression
increases expression		 ISO bexarotene results in decreased expression of GYS2 mRNA
bexarotene results in increased expression of GYS2 mRNA		 CTD PMID:16648578 PMID:23292798 NCBI chr 6:142,368,339...142,418,856
Ensembl chr 6:142,368,339...142,418,835 		JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-BA mRNA CTD PMID:17630414 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797 		JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha multiple interactions
increases expression		 ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-DA mRNA
bexarotene results in increased expression of RT1-DA mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of RT1-DB1 mRNA CTD PMID:17630414 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G H2az1 H2A.Z variant histone 1 decreases expression ISO Bexarotene results in decreased expression of H2AZ1 mRNA CTD PMID:16648578 NCBI chr 3:137,570,248...137,572,683
Ensembl chr 3:137,570,248...137,572,683 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression ISO bexarotene results in decreased expression of HAO2 mRNA CTD PMID:17630414 NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555 		JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 decreases expression ISO bexarotene results in decreased expression of HERPUD1 mRNA CTD PMID:17178900 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO bexarotene results in decreased expression of HMGB2 mRNA CTD PMID:16648578 NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033 		JBrowse link
G Homer1 homer scaffolding protein 1 increases expression ISO bexarotene results in increased expression of HOMER1 mRNA CTD PMID:16648578 NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637 		JBrowse link
G Hp haptoglobin decreases expression ISO bexarotene results in decreased expression of HP mRNA CTD PMID:16648578 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO bexarotene results in increased expression of HPGDS mRNA CTD PMID:16648578 NCBI chr 6:65,094,019...65,121,960
Ensembl chr 6:65,094,277...65,121,892 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression
multiple interactions		 ISO Bexarotene results in increased expression of HSD11B2 mRNA
Bexarotene results in increased expression of and results in increased activity of HSD11B2 protein; Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; LG 100754 inhibits the reaction [Bexarotene results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein]		 CTD PMID:31927052 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO bexarotene results in increased expression of HSD17B12 mRNA CTD PMID:16648578 NCBI chr 2:93,863,042...93,988,254
Ensembl chr 2:93,863,034...93,988,309 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO bexarotene results in decreased expression of HSD17B2 mRNA CTD PMID:16648578 NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766 		JBrowse link
G Hspa4 heat shock protein 4 decreases expression ISO bexarotene results in decreased expression of HSPA4 mRNA CTD PMID:16648578 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284 		JBrowse link
G Hspa9 heat shock protein 9 increases expression ISO bexarotene results in increased expression of HSPA9 mRNA CTD PMID:16648578 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410 		JBrowse link
G Hspb1 heat shock protein 1 increases expression ISO bexarotene results in increased expression of HSPB1 mRNA CTD PMID:16648578 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 decreases expression ISO bexarotene results in decreased expression of HSPH1 mRNA CTD PMID:16648578 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO bexarotene results in increased expression of ID1 mRNA; bexarotene results in increased expression of ID1 protein CTD PMID:17178900 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Ier2 immediate early response 2 decreases expression ISO bexarotene results in decreased expression of IER2 mRNA CTD PMID:17178900 NCBI chr 8:85,387,960...85,389,481
Ensembl chr 8:85,387,960...85,389,483 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 multiple interactions ISO [Bexarotene co-treated with Tamoxifen] results in decreased expression of IFITM1 mRNA CTD PMID:17630414 NCBI chr 7:140,547,342...140,549,740
Ensembl chr 7:140,547,134...140,549,738 		JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO bexarotene results in increased expression of IFNGR1 mRNA CTD PMID:16648578 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO bexarotene results in decreased expression of IGF1 protein CTD PMID:15591091 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf2 insulin-like growth factor 2 increases expression ISO bexarotene results in increased expression of IGF2 mRNA CTD PMID:16648578 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO bexarotene results in increased expression of IGFBP1 mRNA CTD PMID:16648578 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression
multiple interactions		 ISO bexarotene results in increased expression of IGFBP2 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of IGFBP2 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
decreases expression		 ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP3 mRNA
bexarotene results in decreased expression of IGFBP3 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO bexarotene results in increased expression of IGFBP6 mRNA; bexarotene results in increased expression of IGFBP6 protein CTD PMID:17178900 NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP7 mRNA CTD PMID:17630414 NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888 		JBrowse link
G Il15 interleukin 15 increases expression ISO bexarotene results in increased expression of IL15 mRNA CTD PMID:17178900 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il18 interleukin 18 decreases expression ISO bexarotene results in decreased expression of IL18 mRNA CTD PMID:16648578 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions		 ISO bexarotene results in decreased expression of IL4 protein
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of IL4 mRNA]; Bexarotene affects the reaction [Azoxymethane affects the expression of IL4 mRNA]		 CTD PMID:15781672 PMID:24080207 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6ra interleukin 6 receptor, alpha decreases expression ISO bexarotene results in decreased expression of IL6RA mRNA CTD PMID:16648578 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Ins2 insulin II multiple interactions ISO
EXP		 [bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with bexarotene] results in increased expression of SLC27A1 mRNA; [Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased susceptibility to bexarotene		 CTD PMID:10777552 PMID:25932594 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO bexarotene results in increased expression of INSIG1 mRNA CTD PMID:16648578 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660 		JBrowse link
G Insrr insulin receptor-related receptor increases expression ISO bexarotene results in increased expression of INSRR mRNA CTD PMID:16648578 NCBI chr 3:87,704,215...87,723,408
Ensembl chr 3:87,704,258...87,723,408 		JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO bexarotene results in increased expression of IRF1 mRNA CTD PMID:16648578 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Itga7 integrin alpha 7 decreases expression ISO bexarotene results in decreased expression of ITGA7 mRNA CTD PMID:16648578 NCBI chr10:128,769,633...128,794,155
Ensembl chr10:128,769,645...128,794,155 		JBrowse link
G Itgb6 integrin beta 6 increases expression ISO bexarotene results in increased expression of ITGB6 mRNA CTD PMID:17178900 NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO bexarotene results in decreased expression of ITIH3 mRNA CTD PMID:16648578 NCBI chr14:30,630,529...30,645,748
Ensembl chr14:30,630,529...30,645,717 		JBrowse link
G Itm2a integral membrane protein 2A increases expression ISO bexarotene results in increased expression of ITM2A mRNA CTD PMID:17178900 NCBI chr  X:106,440,801...106,446,966
Ensembl chr  X:106,440,705...106,446,982 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 increases expression ISO bexarotene results in increased expression of ITPR1 mRNA CTD PMID:17178900 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070 		JBrowse link
G Ivl involucrin decreases expression ISO bexarotene results in decreased expression of IVL mRNA CTD PMID:8853895 NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042 		JBrowse link
G Jup junction plakoglobin increases expression ISO bexarotene results in increased expression of JUP mRNA CTD PMID:16648578 NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589 		JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of KCNMA1 mRNA CTD PMID:17630414 NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559 		JBrowse link
G Kcnt1 potassium channel, subfamily T, member 1 increases expression ISO bexarotene results in increased expression of KCNT1 mRNA CTD PMID:16648578 NCBI chr 2:25,753,807...25,808,285
Ensembl chr 2:25,753,746...25,808,285 		JBrowse link
G Klf10 Kruppel-like transcription factor 10 decreases expression ISO bexarotene results in decreased expression of KLF10 mRNA CTD PMID:17178900 NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950 		JBrowse link
G Klf9 Kruppel-like transcription factor 9 increases expression
decreases expression		 ISO bexarotene results in increased expression of KLF9 mRNA
bexarotene results in decreased expression of KLF9 mRNA		 CTD PMID:16648578 PMID:26096596 NCBI chr19:23,118,590...23,145,493
Ensembl chr19:23,118,590...23,145,498 		JBrowse link
G Kng1 kininogen 1 increases expression
decreases expression		 EXP
ISO		 Bexarotene results in increased expression of KNG1 mRNA
Bexarotene results in decreased expression of KNG1 mRNA		 CTD PMID:16648578 PMID:17849452 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Krt14 keratin 14 decreases expression ISO bexarotene results in decreased expression of KRT14 mRNA CTD PMID:8853895 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374 		JBrowse link
G Krt15 keratin 15 increases expression ISO bexarotene results in increased expression of KRT15 mRNA CTD PMID:17178900 NCBI chr11:100,022,585...100,026,775
Ensembl chr11:100,022,584...100,026,754 		JBrowse link
G Krt17 keratin 17 decreases expression ISO bexarotene results in decreased expression of KRT17 mRNA; bexarotene results in decreased expression of KRT17 protein CTD PMID:17178900 NCBI chr11:100,147,041...100,151,855
Ensembl chr11:100,147,043...100,151,855 		JBrowse link
G Krt5 keratin 5 decreases expression ISO bexarotene results in decreased expression of KRT5 mRNA CTD PMID:8853895 NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333 		JBrowse link
G Ldhb lactate dehydrogenase B decreases expression ISO bexarotene results in decreased expression of LDHB mRNA CTD PMID:16648578 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 decreases expression ISO bexarotene results in decreased expression of LGALS3 mRNA CTD PMID:16648578 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Lifr LIF receptor alpha multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of LIFR mRNA CTD PMID:17630414 NCBI chr15:7,120,091...7,226,970
Ensembl chr15:7,120,095...7,226,970 		JBrowse link
G Lipa lysosomal acid lipase A decreases expression ISO bexarotene results in decreased expression of LIP1 mRNA CTD PMID:16648578 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874 		JBrowse link
G Lipe lipase, hormone sensitive decreases expression ISO bexarotene results in decreased expression of LIPE mRNA CTD PMID:16648578 NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135 		JBrowse link
G Lman1 lectin, mannose-binding, 1 decreases expression ISO bexarotene results in decreased expression of LMAN1 mRNA CTD PMID:16648578 NCBI chr18:66,113,810...66,135,706
Ensembl chr18:66,113,809...66,155,651 		JBrowse link
G Lox lysyl oxidase decreases expression ISO bexarotene results in decreased expression of LOX mRNA CTD PMID:16648578 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939 		JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression ISO bexarotene results in increased expression of LOXL2 mRNA CTD PMID:17178900 NCBI chr14:69,846,085...69,933,283
Ensembl chr14:69,846,517...69,933,283 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of LRG1 mRNA CTD PMID:17630414 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001 		JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 decreases expression ISO bexarotene results in decreased expression of LRP2 mRNA CTD PMID:16648578 NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409 		JBrowse link
G Lum lumican decreases expression ISO bexarotene results in decreased expression of LUM mRNA CTD PMID:16648578 NCBI chr10:97,401,363...97,408,565
Ensembl chr10:97,400,990...97,408,565 		JBrowse link
G Lypla1 lysophospholipase 1 decreases expression ISO bexarotene results in decreased expression of LYPLA1 mRNA CTD PMID:16648578 NCBI chr 1:4,878,046...4,916,958
Ensembl chr 1:4,878,011...4,918,633 		JBrowse link
G Lyst lysosomal trafficking regulator increases expression ISO bexarotene results in increased expression of LYST mRNA CTD PMID:17630414 NCBI chr13:13,764,896...13,953,388
Ensembl chr13:13,764,982...13,953,388 		JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of XLKD1 mRNA CTD PMID:17630414 NCBI chr 7:110,449,814...110,462,160
Ensembl chr 7:110,449,814...110,462,446 		JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO bexarotene results in increased expression of MAF mRNA CTD PMID:17178900 NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533 		JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) decreases expression ISO bexarotene results in decreased expression of MAFF mRNA CTD PMID:17178900 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276 		JBrowse link
G Maob monoamine oxidase B decreases expression ISO bexarotene results in decreased expression of MAOB mRNA CTD PMID:16648578 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605 		JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO bexarotene results in increased expression of MAP1B mRNA CTD PMID:16648578 NCBI chr13:99,557,972...99,653,110
Ensembl chr13:99,557,954...99,653,048 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression ISO bexarotene results in increased expression of MAP2 mRNA CTD PMID:16648578 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO bexarotene results in increased expression of MAP3K1 mRNA CTD PMID:16648578 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527 		JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 increases expression ISO bexarotene results in increased expression of MAP3K12 mRNA CTD PMID:16648578 NCBI chr15:102,406,079...102,425,311
Ensembl chr15:102,406,081...102,425,499 		JBrowse link
G Mark1 MAP/microtubule affinity regulating kinase 1 increases expression ISO bexarotene results in increased expression of MARK1 mRNA CTD PMID:16648578 NCBI chr 1:184,628,621...184,732,152
Ensembl chr 1:184,628,986...184,731,767 		JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic increases expression ISO bexarotene results in increased expression of ME1 mRNA CTD PMID:16648578 PMID:23292798 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid decreases expression ISO bexarotene results in decreased expression of MFSD2A mRNA CTD PMID:17630414 NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981 		JBrowse link
G Mgp matrix Gla protein multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of MGP mRNA CTD PMID:17630414 NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821 		JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 increases expression ISO bexarotene results in increased expression of MLLT11 mRNA CTD PMID:17178900 NCBI chr 3:95,125,852...95,139,486
Ensembl chr 3:95,126,446...95,139,482 		JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Bexarotene co-treated with GW 3965] results in decreased expression of MLXIPL mRNA; [Bexarotene co-treated with T0901317] results in decreased expression of MLXIPL mRNA CTD PMID:32123961 NCBI chr 5:135,118,744...135,168,622
Ensembl chr 5:135,118,744...135,167,236 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) decreases expression ISO bexarotene results in decreased expression of MMP14 mRNA CTD PMID:16648578 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) decreases expression ISO Bexarotene results in decreased expression of MMP1 mRNA CTD PMID:17178900 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of MRC1 mRNA CTD PMID:17630414 NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868 		JBrowse link
G mt-Co2 cytochrome c oxidase II, mitochondrial decreases expression ISO
EXP		 bexarotene results in decreased expression of COX2 mRNA; bexarotene results in decreased expression of COX2 protein CTD PMID:17178900 NCBI chr MT:7,013...7,696
Ensembl chr MT:7,013...7,696 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase decreases expression ISO bexarotene results in decreased expression of MTHFD2 mRNA CTD PMID:17178900 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890 		JBrowse link
G Muc1 mucin 1, transmembrane increases expression ISO bexarotene results in increased expression of MUC1 mRNA CTD PMID:16648578 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Mug1 murinoglobulin 1 decreases expression ISO bexarotene results in decreased expression of MUG1 mRNA CTD PMID:16648578 NCBI chr 6:121,815,455...121,866,016
Ensembl chr 6:121,815,500...121,866,016 		JBrowse link
G Napa N-ethylmaleimide sensitive fusion protein attachment protein alpha increases expression ISO bexarotene results in increased expression of NAPA mRNA CTD PMID:16648578 NCBI chr 7:15,832,127...15,851,907
Ensembl chr 7:15,832,383...15,851,900 		JBrowse link
G Nat8 N-acetyltransferase 8 (GCN5-related) decreases expression ISO bexarotene results in decreased expression of NAT8 mRNA CTD PMID:17630414 NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064 		JBrowse link
G Ndufaf3 NADH:ubiquinone oxidoreductase complex assembly factor 3 increases expression ISO bexarotene results in increased expression of NDUFAF3 mRNA CTD PMID:16648578 NCBI chr 9:108,442,786...108,444,635
Ensembl chr 9:108,442,736...108,444,633 		JBrowse link
G Neurod2 neurogenic differentiation 2 increases expression ISO bexarotene results in increased expression of NEUROD2 mRNA CTD PMID:16648578 NCBI chr11:98,216,241...98,220,471
Ensembl chr11:98,216,241...98,220,474 		JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of NIM1K mRNA CTD PMID:17630414 NCBI chr13:120,171,630...120,217,418
Ensembl chr13:120,171,630...120,217,418 		JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of NOL3 mRNA CTD PMID:17630414 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression EXP bexarotene results in decreased expression of NOS2 mRNA CTD PMID:17849452 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Npy neuropeptide Y increases expression ISO bexarotene results in increased expression of NPY mRNA CTD PMID:17630414 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression
multiple interactions		 ISO bexarotene results in increased expression of NR0B2 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of NR0B2 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of NR0B2 mRNA; [Bexarotene co-treated with T0901317] results in increased expression of NR0B2 mRNA
Bexarotene results in increased expression of NR0B2 mRNA		 CTD PMID:17630414 PMID:23292798 PMID:32123961 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
decreases expression		 ISO [Bexarotene co-treated with GW 3965] results in increased expression of NR1H3 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of NR1H3 mRNA; [Bexarotene co-treated with T0901317] results in increased expression of NR1H3 mRNA; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]
Bexarotene results in decreased expression of NR1H3 mRNA		 CTD PMID:25932594 PMID:32123961 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions		 ISO bexarotene results in increased expression of NR1I3 mRNA
Bexarotene binds to and results in increased activity of NR1I3 protein alternative form		 CTD PMID:17630414 PMID:31312845 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO [Bexarotene co-treated with GW 3965] results in increased expression of NRIP1 mRNA; [Bexarotene co-treated with T0901317] results in increased expression of NRIP1 mRNA CTD PMID:32123961 NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 increases expression ISO bexarotene results in increased expression of OAZ1 mRNA CTD PMID:16648578 NCBI chr10:80,662,490...80,665,124
Ensembl chr10:80,662,516...80,665,124 		JBrowse link
G Odc1 ornithine decarboxylase, structural 1 decreases expression ISO
EXP		 bexarotene results in decreased expression of ODC1 mRNA CTD PMID:17178900 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506 		JBrowse link
G Orm1 orosomucoid 1 decreases expression ISO bexarotene results in decreased expression of ORM1 mRNA CTD PMID:16648578 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400 		JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide increases expression ISO bexarotene results in increased expression of P4HB mRNA CTD PMID:16648578 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079 		JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated decreases expression ISO bexarotene results in decreased expression of PDE2A mRNA CTD PMID:16648578 NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 increases expression ISO bexarotene results in increased expression of PDK2 mRNA CTD PMID:16648578 NCBI chr11:94,917,084...94,932,197
Ensembl chr11:94,917,084...94,932,180 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 increases expression ISO bexarotene results in increased expression of PDK4 mRNA CTD PMID:16648578 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309 		JBrowse link
G Per2 period circadian clock 2 decreases expression ISO bexarotene results in decreased expression of PER2 mRNA CTD PMID:17178900 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of PEX11A mRNA CTD PMID:17630414 NCBI chr 7:79,385,705...79,392,879
Ensembl chr 7:79,385,705...79,392,879 		JBrowse link
G Pex19 peroxisomal biogenesis factor 19 decreases expression ISO bexarotene results in decreased expression of PEX19 mRNA CTD PMID:16648578 NCBI chr 1:171,954,322...171,964,064
Ensembl chr 1:171,954,322...171,964,060 		JBrowse link
G Pf4 platelet factor 4 increases expression ISO bexarotene results in increased expression of PF4 mRNA CTD PMID:17630414 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO bexarotene binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta increases expression ISO bexarotene results in increased expression of PIK3CB mRNA CTD PMID:16648578 NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO bexarotene promotes the reaction [rosiglitazone results in increased expression of PIK3R1 mRNA] CTD PMID:10548525 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression ISO bexarotene results in increased expression of PIK3R3 mRNA CTD PMID:16648578 NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253
Ensembl chr 4:116,078,815...116,160,253 		JBrowse link
G Pkib protein kinase inhibitor beta, cAMP dependent, testis specific multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of PKIB mRNA CTD PMID:17630414 NCBI chr10:57,508,077...57,617,208
Ensembl chr10:57,508,077...57,617,208 		JBrowse link
G Plagl1 pleiomorphic adenoma gene-like 1 decreases expression ISO bexarotene results in decreased expression of PLAGL1 mRNA CTD PMID:16648578 NCBI chr10:12,966,576...13,007,438
Ensembl chr10:12,936,248...13,007,438 		JBrowse link
G Plat plasminogen activator, tissue increases expression ISO bexarotene results in increased expression of PLAT mRNA CTD PMID:17178900 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO bexarotene results in decreased expression of PLAUR mRNA CTD PMID:17178900 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Plin1 perilipin 1 increases expression EXP bexarotene results in increased expression of PLIN1 mRNA CTD PMID:25932594 NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO bexarotene results in increased expression of PLOD2 mRNA CTD PMID:17178900 NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481 		JBrowse link
G Pno1 partner of NOB1 homolog decreases expression ISO bexarotene results in decreased expression of PNO1 mRNA CTD PMID:17178900 NCBI chr11:17,153,198...17,161,589
Ensembl chr11:17,153,198...17,161,568 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 increases expression ISO bexarotene results in increased expression of PNRC1 mRNA CTD PMID:17178900 NCBI chr 4:33,245,423...33,248,787
Ensembl chr 4:33,245,423...33,290,163 		JBrowse link
G Pola1 polymerase (DNA directed), alpha 1 increases expression ISO bexarotene results in increased expression of POLA1 mRNA CTD PMID:16648578 NCBI chr  X:92,348,372...92,675,993
Ensembl chr  X:92,348,373...92,675,761 		JBrowse link
G Pon1 paraoxonase 1 decreases expression ISO bexarotene results in decreased expression of PON1 mRNA CTD PMID:16648578 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO bexarotene results in increased expression of POR mRNA CTD PMID:16648578 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform increases expression ISO bexarotene results in increased expression of PPP2CB mRNA CTD PMID:16648578 NCBI chr 8:34,089,672...34,109,831
Ensembl chr 8:34,089,653...34,109,469 		JBrowse link
G Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha increases expression ISO bexarotene results in increased expression of PPP2R1A mRNA CTD PMID:16648578 NCBI chr17:21,165,716...21,186,167
Ensembl chr17:21,165,573...21,186,178 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 decreases expression ISO bexarotene results in decreased expression of PPT1 mRNA CTD PMID:16648578 NCBI chr 4:122,729,879...122,752,968
Ensembl chr 4:122,730,035...122,752,968 		JBrowse link
G Prdx6 peroxiredoxin 6 increases expression ISO bexarotene results in increased expression of PRDX6 mRNA CTD PMID:16648578 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789 		JBrowse link
G Prkar2b protein kinase, cAMP dependent regulatory, type II beta decreases expression ISO bexarotene results in decreased expression of PRKAR2B mRNA CTD PMID:16648578 NCBI chr12:32,008,468...32,111,639
Ensembl chr12:32,008,475...32,111,295 		JBrowse link
G Prlhr prolactin releasing hormone receptor increases expression ISO bexarotene results in increased expression of PRLHR mRNA CTD PMID:16648578 NCBI chr19:60,454,079...60,457,907
Ensembl chr19:60,455,170...60,456,742 		JBrowse link
G Prlr prolactin receptor multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of PRLR mRNA CTD PMID:17630414 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
G Prnp prion protein decreases expression ISO bexarotene results in decreased expression of PRNP mRNA CTD PMID:16648578 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349 		JBrowse link
G Prom1 prominin 1 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in decreased expression of PROM1 mRNA CTD PMID:17630414 NCBI chr 5:44,150,963...44,260,850
Ensembl chr 5:44,150,962...44,259,374 		JBrowse link
G Prr15 proline rich 15 multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of PRR15 mRNA CTD PMID:17630414 NCBI chr 6:54,290,442...54,320,421
Ensembl chr 6:54,302,820...54,307,186 		JBrowse link
G Psap prosaposin increases expression ISO bexarotene results in increased expression of PSAP mRNA CTD PMID:16648578 NCBI chr10:60,113,436...60,138,379
Ensembl chr10:60,113,449...60,138,376 		JBrowse link
G Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 increases expression ISO bexarotene results in increased expression of PSMC2 mRNA CTD PMID:16648578 NCBI chr 5:21,990,273...22,008,785
Ensembl chr 5:21,990,281...22,008,785 		JBrowse link
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 increases expression ISO bexarotene results in increased expression of PSMD4 mRNA CTD PMID:16648578 NCBI chr 3:94,939,999...94,949,880
Ensembl chr 3:94,940,005...94,949,925 		JBrowse link
G Pspn persephin increases expression ISO bexarotene results in increased expression of PSPN mRNA CTD PMID:16648578 NCBI chr17:57,306,253...57,307,105
Ensembl chr17:57,306,457...57,307,018 		JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) decreases expression EXP bexarotene results in decreased expression of PTGER3 mRNA CTD PMID:17849452 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) decreases expression EXP bexarotene results in decreased expression of PTGER4 mRNA CTD PMID:17849452 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Ptms parathymosin increases expression ISO bexarotene results in increased expression of PTMS mRNA CTD PMID:16648578 NCBI chr 6:124,890,638...124,894,909
Ensembl chr 6:124,890,644...124,897,066 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C increases expression ISO bexarotene results in increased expression of PTPRC mRNA CTD PMID:16648578 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Qpct glutaminyl-peptide cyclotransferase (glutaminyl cyclase) increases expression ISO bexarotene results in increased expression of QPCT mRNA CTD PMID:16648578 NCBI chr17:79,359,335...79,397,807
Ensembl chr17:79,359,335...79,397,807 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression ISO bexarotene results in increased expression of RAB11B mRNA CTD PMID:16648578 NCBI chr17:33,961,458...33,979,460
Ensembl chr17:33,961,458...33,979,504 		JBrowse link
G Rab7 RAB7, member RAS oncogene family increases expression ISO bexarotene results in increased expression of RAB7 mRNA CTD PMID:16648578 NCBI chr 6:87,976,088...88,022,252
Ensembl chr 6:87,976,088...88,022,252 		JBrowse link
G Rabep2 rabaptin, RAB GTPase binding effector protein 2 increases expression ISO bexarotene results in increased expression of RABEP2 mRNA CTD PMID:16648578 NCBI chr 7:126,027,596...126,045,079
Ensembl chr 7:126,027,931...126,048,417 		JBrowse link
G Rarb retinoic acid receptor, beta increases expression
multiple interactions		 ISO Bexarotene results in increased expression of RARB mRNA
CD2665 promotes the reaction [Bexarotene results in increased expression of RARB mRNA]; UVI 3003 inhibits the reaction [Bexarotene results in increased expression of RARB mRNA]		 CTD PMID:17178900 PMID:35483669 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924 		JBrowse link
G Rasl11a RAS-like, family 11, member A increases expression ISO bexarotene results in increased expression of RASL11A mRNA CTD PMID:16648578 NCBI chr 5:146,781,881...146,784,536
Ensembl chr 5:146,781,881...146,784,537 		JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 decreases expression EXP bexarotene results in decreased expression of RASSF1 mRNA CTD PMID:17849452 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO bexarotene results in decreased phosphorylation of RB1 protein CTD PMID:16273314 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rdh1 retinol dehydrogenase 1 (all trans) increases expression ISO Bexarotene results in increased expression of RDH2 mRNA CTD PMID:16648578 NCBI chr10:127,595,595...127,604,168
Ensembl chr10:127,595,590...127,604,166 		JBrowse link
G Renbp renin binding protein increases expression ISO bexarotene results in increased expression of RENBP mRNA CTD PMID:16648578 NCBI chr  X:72,965,727...72,974,408
Ensembl chr  X:72,965,727...72,974,456 		JBrowse link
G Rest RE1-silencing transcription factor increases expression ISO bexarotene results in increased expression of REST mRNA CTD PMID:16648578 NCBI chr 5:77,413,273...77,434,279
Ensembl chr 5:77,413,338...77,434,279 		JBrowse link
G Rgn regucalcin decreases expression ISO bexarotene results in decreased expression of RGN mRNA CTD PMID:16648578 NCBI chr  X:20,413,980...20,428,328
Ensembl chr  X:20,416,026...20,428,328 		JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression ISO bexarotene results in decreased expression of RIDA mRNA CTD PMID:16648578 NCBI chr15:34,484,168...34,495,392
Ensembl chr15:34,484,167...34,495,401 		JBrowse link
G Rnase1 ribonuclease, RNase A family, 1 (pancreatic) increases expression ISO Bexarotene results in increased expression of RNASE1 mRNA CTD PMID:16648578 NCBI chr14:51,382,459...51,384,224
Ensembl chr14:51,382,455...51,384,242 		JBrowse link
G Rpl18a ribosomal protein L18A increases expression ISO bexarotene results in increased expression of RPL18A mRNA CTD PMID:16648578 NCBI chr 8:71,347,366...71,350,087
Ensembl chr 8:71,347,366...71,350,056 		JBrowse link
G Rpl22 ribosomal protein L22 increases expression ISO bexarotene results in increased expression of RPL22 mRNA CTD PMID:16648578 NCBI chr 4:152,408,893...152,418,539
Ensembl chr 4:152,410,199...152,418,528 		JBrowse link
G Rpl7a ribosomal protein L7A increases expression ISO bexarotene results in increased expression of RPL7A mRNA CTD PMID:16648578 NCBI chr 2:26,800,697...26,803,330
Ensembl chr 2:26,800,776...26,803,330 		JBrowse link
G Rps2 ribosomal protein S2 increases expression ISO bexarotene results in increased expression of RPS2 mRNA CTD PMID:16648578 NCBI chr17:24,939,037...24,940,901
Ensembl chr17:24,937,090...24,940,903 		JBrowse link
G Rpsa ribosomal protein SA increases expression ISO bexarotene results in increased expression of RPSA mRNA CTD PMID:16648578 NCBI chr 9:119,956,832...119,961,435
Ensembl chr 9:119,956,755...119,961,435 		JBrowse link
G Rtn4 reticulon 4 increases expression ISO bexarotene results in increased expression of RTN4 mRNA CTD PMID:17630414 NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331 		JBrowse link
G Rxra retinoid X receptor alpha affects binding
multiple interactions		 ISO Bexarotene binds to RXRA protein
Bexarotene binds to and results in increased activity of RXRA protein; RXRA promotes the reaction [Bexarotene results in increased expression of APOA2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of CYP2B6 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein]		 CTD PMID:8668150 PMID:21218783 PMID:23843199 PMID:31312845 PMID:31566444 More... NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO bexarotene binds to RXRB protein CTD PMID:23843199 NCBI chr17:34,250,786...34,257,377
Ensembl chr17:34,250,786...34,257,373 		JBrowse link
G Rxrg retinoid X receptor gamma affects binding
decreases expression		 ISO
EXP		 bexarotene binds to RXRG protein
bexarotene results in decreased expression of RXRG mRNA		 CTD PMID:17849452 PMID:23843199 NCBI chr 1:167,425,902...167,467,191
Ensembl chr 1:167,425,953...167,467,192 		JBrowse link
G S100a10 S100 calcium binding protein A10 (calpactin) decreases expression ISO bexarotene results in decreased expression of S100A10 mRNA CTD PMID:16648578 NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950 		JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression ISO bexarotene results in increased expression of S100A9 mRNA CTD PMID:16648578 PMID:17178900 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028 		JBrowse link
G S100b S100 protein, beta polypeptide, neural decreases expression ISO bexarotene results in decreased expression of S100B mRNA CTD PMID:16648578 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
G Saal1 serum amyloid A-like 1 increases expression ISO Bexarotene results in increased expression of SAA2 mRNA CTD PMID:16648578 NCBI chr 7:46,336,581...46,360,085
Ensembl chr 7:46,335,532...46,360,104 		JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 increases expression
multiple interactions		 EXP
ISO		 bexarotene results in increased expression of SCD1 mRNA
[Tamoxifen co-treated with bexarotene] results in increased expression of SCD1 mRNA		 CTD PMID:17178900 PMID:17630414 PMID:23292798 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression
multiple interactions		 ISO bexarotene results in increased expression of SCD2 mRNA
Bexarotene results in increased expression of SCD mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of SCD mRNA; [Bexarotene co-treated with T0901317] results in increased expression of SCD mRNA		 CTD PMID:16648578 PMID:17178900 PMID:17630414 PMID:32123961 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303 		JBrowse link
G Scp2 sterol carrier protein 2, liver decreases expression ISO bexarotene results in decreased expression of SCP2 mRNA CTD PMID:16648578 NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195 		JBrowse link
G Sdc2 syndecan 2 decreases expression ISO bexarotene results in decreased expression of SDC2 mRNA CTD PMID:16648578 NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression ISO bexarotene results in decreased expression of SERPINA3N mRNA CTD PMID:16648578 NCBI chr12:104,372,967...104,380,588
Ensembl chr12:104,372,988...104,380,588 		JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 decreases expression ISO bexarotene results in decreased expression of SERPIND1 mRNA CTD PMID:16648578 NCBI chr16:17,149,235...17,161,438
Ensembl chr16:17,149,235...17,161,439 		JBrowse link
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 increases expression ISO bexarotene results in increased expression of SERPINH1 mRNA CTD PMID:17630414 NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446 		JBrowse link
G Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) decreases expression ISO bexarotene results in decreased expression of SFPQ mRNA CTD PMID:16648578 NCBI chr 4:126,914,504...126,944,894
Ensembl chr 4:126,915,117...126,930,806 		JBrowse link
G Shh sonic hedgehog increases expression ISO bexarotene results in increased expression of SHH mRNA CTD PMID:26096596 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO bexarotene results in decreased expression of SIAH2 mRNA CTD PMID:17178900 NCBI chr 3:58,582,370...58,599,857
Ensembl chr 3:58,582,359...58,599,821 		JBrowse link
G Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 decreases expression ISO bexarotene results in decreased expression of SLC1A3 mRNA CTD PMID:16648578 NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248 		JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 increases expression
multiple interactions		 ISO
EXP		 bexarotene results in increased expression of SLC27A1 mRNA
[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with bexarotene] results in increased expression of SLC27A1 mRNA		 CTD PMID:10777552 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946 		JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 decreases expression ISO bexarotene results in decreased expression of SLC27A2 mRNA CTD PMID:16648578 NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 increases expression ISO bexarotene results in increased expression of SLC2A2 mRNA CTD PMID:16648578 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 multiple interactions ISO [bexarotene co-treated with rosiglitazone] results in increased expression of SLC2A4 mRNA CTD PMID:10548525 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Slc35b1 solute carrier family 35, member B1 increases expression ISO bexarotene results in increased expression of SLC35B1 mRNA CTD PMID:16648578 NCBI chr11:95,275,696...95,282,602
Ensembl chr11:95,275,518...95,282,602 		JBrowse link
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 increases expression ISO bexarotene results in increased expression of SLC6A6 mRNA CTD PMID:16648578 NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047 		JBrowse link
G Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 decreases expression ISO bexarotene results in decreased expression of SLC7A1 mRNA CTD PMID:17178900 NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714 		JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 decreases expression ISO bexarotene results in decreased expression of SLC7A5 mRNA CTD PMID:17178900 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433 		JBrowse link
G Smad5 SMAD family member 5 increases expression ISO bexarotene results in increased expression of SMAD5 mRNA CTD PMID:17178900 NCBI chr13:56,850,804...56,890,191
Ensembl chr13:56,850,823...56,890,190 		JBrowse link
G Sncg synuclein, gamma decreases expression ISO bexarotene results in decreased expression of SNCG mRNA CTD PMID:16648578 NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 increases expression ISO bexarotene results in increased expression of SND1 mRNA CTD PMID:16648578 NCBI chr 6:28,480,332...28,935,161
Ensembl chr 6:28,475,138...28,935,161 		JBrowse link
G Snn stannin decreases expression ISO bexarotene results in decreased expression of SNN mRNA CTD PMID:16648578 NCBI chr16:10,884,162...10,892,849
Ensembl chr16:10,878,809...10,892,849 		JBrowse link
G Sord sorbitol dehydrogenase decreases expression ISO bexarotene results in decreased expression of SORD mRNA CTD PMID:16648578 NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821 		JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing multiple interactions ISO [bexarotene co-treated with Tamoxifen] results in increased expression of SORL1 mRNA CTD PMID:17630414 NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593 		JBrowse link
G Sp7 Sp7 transcription factor 7 decreases expression
multiple interactions		 EXP
ISO		 bexarotene results in decreased expression of SP7 mRNA
bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]		 CTD PMID:25932594 NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617 		JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein increases expression ISO bexarotene results in increased expression of SPARC mRNA CTD PMID:17178900 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 multiple interactions
increases expression		 ISO [bexarotene co-treated with Tamoxifen] results in increased expression of SPINK1 mRNA
bexarotene results in increased expression of SPINK1 mRNA		 CTD PMID:16648578 PMID:17630414 NCBI chr18:43,861,134...43,870,302
Ensembl chr18:43,861,147...43,870,622 		JBrowse link
G Spmip11 sperm microtubule inner protein 11 multiple interactions ISO [Bexarotene co-treated with Tamoxifen] results in increased expression of SPMIP11 mRNA CTD PMID:17630414 NCBI chr15:98,468,885...98,487,469
Ensembl chr15:98,468,885...98,487,461 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO bexarotene results in decreased expression of SPP1 mRNA CTD PMID:16648578 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Spp2 secreted phosphoprotein 2 decreases expression ISO bexarotene results in decreased expression of SPP2 mRNA CTD PMID:16648578 NCBI chr 1:88,334,688...88,356,022
Ensembl chr 1:88,334,683...88,354,160 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO bexarotene results in increased expression of SQSTM1 mRNA CTD PMID:16648578 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression ISO bexarotene results in decreased expression of SRD5A1 mRNA CTD PMID:16648578 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions		 ISO bexarotene results in increased expression of SREBF1 mRNA
[Bexarotene co-treated with GW 3965] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with paxilline] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with T0901317] results in increased expression of SREBF1 mRNA; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
Bexarotene results in increased expression of SREBF1 mRNA		 CTD PMID:23292798 PMID:25932594 PMID:32123961 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 decreases expression ISO bexarotene results in decreased expression of SRSF2 mRNA CTD PMID:17178900 NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920 		JBrowse link
G Sult1b1 sulfotransferase family 1B, member 1 decreases expression ISO bexarotene results in decreased expression of SULT1B1 mRNA CTD PMID:16648578 NCBI chr 5:87,661,186...87,686,054
Ensembl chr 5:87,661,198...87,686,054 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 decreases expression ISO bexarotene results in decreased expression of SULT2A1 mRNA CTD PMID:16648578 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334 		JBrowse link
G Tacr2 tachykinin receptor 2 increases expression ISO bexarotene results in increased expression of TACR2 mRNA CTD PMID:16648578 NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase increases expression ISO bexarotene results in increased expression of TECR mRNA CTD PMID:16648578 NCBI chr 8:84,298,327...84,321,120
Ensembl chr 8:84,298,327...84,334,600 		JBrowse link
G Tg thyroglobulin increases expression ISO bexarotene results in increased expression of TG mRNA CTD PMID:16648578 NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO bexarotene results in increased expression of TGFB3 mRNA CTD PMID:16648578 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Tgm1 transglutaminase 1, K polypeptide decreases expression ISO bexarotene results in decreased expression of TGM1 mRNA CTD PMID:8853895 NCBI chr14:55,937,466...55,951,378
Ensembl chr14:55,937,466...55,951,383 		JBrowse link
G Tgm2 transglutaminase 2, C polypeptide increases expression
multiple interactions		 ISO
EXP		 bexarotene results in increased expression of TGM2 mRNA
diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of TGM2 mRNA]		 CTD PMID:17178900 PMID:21622945 PMID:25932594 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO bexarotene binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832 		JBrowse link
G Tm4sf1 transmembrane 4 superfamily member 1 increases expression ISO bexarotene results in increased expression of TM4SF1 mRNA CTD PMID:17178900 NCBI chr 3:57,193,038...57,295,150
Ensembl chr 3:57,193,032...57,209,409
Ensembl chr 3:57,193,032...57,209,409 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression ISO bexarotene results in increased expression of TMED2 mRNA CTD PMID:16648578 NCBI chr 5:124,678,835...124,688,566
Ensembl chr 5:124,678,758...124,688,569 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression ISO bexarotene results in increased expression of TNFRSF1A mRNA CTD PMID:16648578 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tns1 tensin 1 increases expression ISO bexarotene results in increased expression of TNS1 mRNA CTD PMID:16648578 NCBI chr 1:73,949,391...74,163,707
Ensembl chr 1:73,949,390...74,163,608 		JBrowse link
G Tpm1 tropomyosin 1, alpha increases expression ISO bexarotene results in increased expression of TPM1 mRNA CTD PMID:16648578 NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688 		JBrowse link
G Tpm3 tropomyosin 3, gamma increases expression ISO bexarotene results in increased expression of TPM3 mRNA CTD PMID:16648578 NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209 		JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO bexarotene results in increased expression of TPM4 mRNA CTD PMID:16648578 NCBI chr 8:72,889,132...72,906,986
Ensembl chr 8:72,884,018...72,906,986 		JBrowse link
G Trf transferrin increases expression ISO bexarotene results in increased expression of TF mRNA CTD PMID:16648578 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO bexarotene results in increased phosphorylation of and results in increased activity of TP53 protein CTD PMID:19067706 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp73 transformation related protein 73 increases expression ISO bexarotene results in increased expression of TP73 protein CTD PMID:19067706 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO bexarotene results in increased expression of TSC22D3 mRNA CTD PMID:17178900 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408 		JBrowse link
G Ttr transthyretin decreases expression ISO bexarotene results in decreased expression of TTR mRNA CTD PMID:16648578 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Tuba1a tubulin, alpha 1A increases expression ISO bexarotene results in increased expression of TUBA1A mRNA CTD PMID:16648578 NCBI chr15:98,847,728...98,851,382
Ensembl chr15:98,847,718...98,851,584 		JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 decreases expression ISO bexarotene results in decreased expression of UAP1 mRNA CTD PMID:17178900 NCBI chr 1:169,967,473...170,002,358
Ensembl chr 1:169,969,507...170,002,526 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions ISO bexarotene promotes the reaction [rosiglitazone results in increased expression of UCP2 mRNA] CTD PMID:10548525 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 increases expression ISO bexarotene results in increased expression of VAMP8 mRNA CTD PMID:17178900 NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO bexarotene results in increased expression of VEGFA mRNA CTD PMID:16648578 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO bexarotene results in decreased expression of XBP1 mRNA CTD PMID:17178900 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide decreases expression ISO bexarotene results in decreased expression of YWHAH mRNA CTD PMID:16648578 NCBI chr 5:33,176,160...33,185,310
Ensembl chr 5:33,176,160...33,185,310 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression ISO bexarotene results in increased expression of ZBTB16 mRNA CTD PMID:23292798 NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 increases expression ISO bexarotene results in increased expression of ZP3 mRNA CTD PMID:16648578 NCBI chr 5:136,008,959...136,017,478
Ensembl chr 5:136,008,953...136,017,478 		JBrowse link
G Zp3r zona pellucida 3 receptor decreases expression ISO bexarotene results in decreased expression of C4BPA mRNA CTD PMID:16648578 NCBI chr 1:130,474,847...130,557,371
Ensembl chr 1:130,504,450...130,557,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    role 22292
      application 21907
        pharmaceutical 21262
          drug 21262
            antineoplastic agent 18963
              bexarotene 446
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22182
                    p-block element atom 22182
                      carbon group element atom 21984
                        carbon atom 21924
                          organic molecular entity 21924
                            heteroorganic entity 21565
                              organochalcogen compound 21051
                                organooxygen compound 20899
                                  carbon oxoacid 19649
                                    carboxylic acid 19645
                                      aromatic carboxylic acid 12937
                                        benzoic acids 12915
                                          bexarotene 446
paths to the root