Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hpgds (hematopoietic prostaglandin D synthase) Mus musculus
Symbol: Hpgds
Name: hematopoietic prostaglandin D synthase
Description: Exhibits prostaglandin-D synthase activity. Involved in negative regulation of male germ cell proliferation and prostaglandin metabolic process. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human HPGDS (hematopoietic prostaglandin D synthase); PARTICIPATES IN prostaglandin biosynthetic pathway; arachidonic acid metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutathione S-transferase; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; glutathione-requiring prostaglandin D synthase; GST class-sigma; H-PGDS; MGC151112; MGC151114; prostaglandin D2 synthase 2, hematopoietic; prostaglandin-H2 D-isomerase; Ptgds2
Homo sapiens (human) : HPGDS (hematopoietic prostaglandin D synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hpgds (hematopoietic prostaglandin D synthase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HPGDS (hematopoietic prostaglandin D synthase)
Canis lupus familiaris (dog) : HPGDS (hematopoietic prostaglandin D synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpgds (hematopoietic prostaglandin D synthase)
Sus scrofa (pig) : HPGDS (hematopoietic prostaglandin D synthase)
Chlorocebus sabaeus (African green monkey) : HPGDS (hematopoietic prostaglandin D synthase)
Heterocephalus glaber (naked mole-rat) : Hpgds (hematopoietic prostaglandin D synthase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl665,117,293 - 65,144,908 (-)EnsemblGRCm38mm10GRCm38
GRCm38665,117,293 - 65,144,981 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37665,067,287 - 65,094,724 (-)NCBIGRCm37mm9NCBIm37
MGSCv36665,048,942 - 65,074,308 (-)NCBImm8
Celera667,246,090 - 67,273,526 (-)NCBICelera
Cytogenetic Map6C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hpgds
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737605
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.