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Gene: Hpgds (hematopoietic prostaglandin D synthase) Mus musculus
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Symbol: Hpgds
Name: hematopoietic prostaglandin D synthase
Description: Exhibits prostaglandin-D synthase activity. Involved in negative regulation of male germ cell proliferation and prostaglandin metabolic process. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human HPGDS (hematopoietic prostaglandin D synthase); PARTICIPATES IN prostaglandin biosynthetic pathway; arachidonic acid metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutathione S-transferase; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; glutathione-requiring prostaglandin D synthase; GST class-sigma; H-PGDS; MGC151112; MGC151114; prostaglandin D2 synthase 2, hematopoietic; prostaglandin-H2 D-isomerase; Ptgds2
Orthologs:
Homo sapiens (human) : HPGDS (hematopoietic prostaglandin D synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hpgds (hematopoietic prostaglandin D synthase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HPGDS (hematopoietic prostaglandin D synthase)
Canis lupus familiaris (dog) : HPGDS (hematopoietic prostaglandin D synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpgds (hematopoietic prostaglandin D synthase)
Sus scrofa (pig) : HPGDS (hematopoietic prostaglandin D synthase)
Chlorocebus sabaeus (African green monkey) : HPGDS (hematopoietic prostaglandin D synthase)
Heterocephalus glaber (naked mole-rat) : Hpgds (hematopoietic prostaglandin D synthase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl665,117,293 - 65,144,908 (-)EnsemblGRCm38mm10GRCm38
GRCm38665,117,293 - 65,144,981 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37665,067,287 - 65,094,724 (-)NCBIGRCm37mm9NCBIm37
MGSCv36665,048,942 - 65,074,308 (-)NCBImm8
Celera667,246,090 - 67,273,526 (-)NCBICelera
Cytogenetic Map6C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hpgds
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737605
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.