Dab2 (disabled 2, mitogen-responsive phosphoprotein) - Rat Genome Database

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Gene: Dab2 (disabled 2, mitogen-responsive phosphoprotein) Mus musculus
Analyze
Symbol: Dab2
Name: disabled 2, mitogen-responsive phosphoprotein
RGD ID: 731452
MGI Page MGI
Description: Exhibits several functions, including AP-2 adaptor complex binding activity; clathrin adaptor activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including endocytosis; hemopoiesis; and positive regulation of cellular metabolic process. Localizes to apical plasma membrane; clathrin coat of coated pit; and nucleus. Is expressed in several structures, including central nervous system; egg cylinder; embryo mesenchyme; future hindbrain roof plate; and metanephros. Orthologous to human DAB2 (DAB adaptor protein 2); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; endocytosis pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730435J12Rik; AA960054; adaptor molecule disabled-2; AI957090; D15Wsu122; D15Wsu122e; D630005B22Rik; differentially expressed in ovarian carcinoma 2; disabled homolog 2; Doc-2; Doc2; mitogen-responsive phosphoprotein; p9; p96; RIKEN cDNA D630005B22 gene
RGD Orthologs
Human
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,329,269 - 6,470,196 (+)NCBIGRCm39mm39
GRCm39 Ensembl156,329,269 - 6,470,193 (+)Ensembl
GRCm38156,299,788 - 6,440,715 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,299,788 - 6,440,712 (+)EnsemblGRCm38mm10GRCm38
MGSCv37156,249,789 - 6,390,712 (+)NCBIGRCm37mm9NCBIm37
MGSCv36156,247,064 - 6,387,927 (+)NCBImm8
Celera156,148,799 - 6,289,867 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map152.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aldosterone  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buspirone  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chloroprene  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
dichromium trioxide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (ISO)
etoposide  (ISO)
exemestane  (ISO)
fenamidone  (EXP)
fipronil  (ISO)
flutamide  (ISO)
fragrance  (ISO)
furan  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
hypochlorous acid  (EXP)
juglone  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
methotrexate  (EXP)
methylphenidate  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nimesulide  (ISO)
okadaic acid  (ISO)
oxaliplatin  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
PhIP  (ISO)
phytoestrogen  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
succimer  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
tetradecane  (ISO)
theophylline  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
undecane  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IEA)
cell differentiation  (IEA)
cell morphogenesis involved in differentiation  (IMP)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (IDA,ISO)
clathrin coat assembly  (IDA,ISO)
endocytosis  (IEA)
endoderm development  (IMP)
excretion  (IMP)
hematopoietic stem cell proliferation  (IDA)
in utero embryonic development  (IMP)
integrin-mediated signaling pathway  (ISO)
leading edge cell differentiation  (ISO)
myeloid cell differentiation  (IEP)
negative regulation of androgen receptor signaling pathway  (ISO)
negative regulation of apoptotic process  (IMP,ISO)
negative regulation of canonical Wnt signaling pathway  (IBA,ISO)
negative regulation of cell growth  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of extrinsic apoptotic signaling pathway  (IMP)
negative regulation of neuron projection development  (ISO)
negative regulation of protein binding  (ISO)
negative regulation of protein localization to plasma membrane  (IMP,ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
pinocytosis  (IMP)
positive regulation of aldosterone biosynthetic process  (ISO)
positive regulation of aldosterone secretion  (ISO)
positive regulation of cell adhesion  (IDA,IMP)
positive regulation of cell migration  (IMP,ISO)
positive regulation of clathrin-dependent endocytosis  (IDA,ISO)
positive regulation of early endosome to late endosome transport  (ISO)
positive regulation of endocytosis  (IBA,ISO)
positive regulation of epithelial to mesenchymal transition  (IMP,ISO)
positive regulation of integrin-mediated signaling pathway  (IMP)
positive regulation of pathway-restricted SMAD protein phosphorylation  (IMP,ISO)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of receptor internalization  (IMP)
positive regulation of receptor recycling  (IMP)
positive regulation of SMAD protein signal transduction  (ISO)
positive regulation of substrate adhesion-dependent cell spreading  (IDA,IMP,ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription elongation from RNA polymerase II promoter  (IMP)
positive regulation of transforming growth factor beta receptor signaling pathway  (ISO)
positive regulation of Wnt signaling pathway, planar cell polarity pathway  (ISO)
protein transport  (IEA)
receptor-mediated endocytosis  (IBA,IPI)
regulation of Rho-dependent protein serine/threonine kinase activity  (ISO)
response to salt  (ISO)
response to steroid hormone  (ISO)
Wnt signaling pathway  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7775479   PMID:8889548   PMID:9569023   PMID:10340473   PMID:10349636   PMID:10488064   PMID:10725249   PMID:10779506   PMID:10922068   PMID:10944463   PMID:11042159   PMID:11076861  
PMID:11104669   PMID:11247302   PMID:11368898   PMID:11823414   PMID:11906161   PMID:11927540   PMID:11967127   PMID:12040188   PMID:12234931   PMID:12413896   PMID:12477932   PMID:12805222  
PMID:12826668   PMID:14596919   PMID:14660441   PMID:15489334   PMID:15592455   PMID:15596140   PMID:15734730   PMID:15769480   PMID:15870384   PMID:15894542   PMID:16109395   PMID:16141072  
PMID:16141073   PMID:16263760   PMID:16602821   PMID:16629596   PMID:16678776   PMID:16816378   PMID:16887818   PMID:16984970   PMID:17182866   PMID:17339320   PMID:17671122   PMID:17762867  
PMID:18083160   PMID:18680569   PMID:18725515   PMID:18816845   PMID:19191217   PMID:19191218   PMID:19521566   PMID:19581412   PMID:19581931   PMID:19767570   PMID:19850877   PMID:20154680  
PMID:20351096   PMID:20881059   PMID:20925113   PMID:21146513   PMID:21677750   PMID:21873635   PMID:22323290   PMID:22411869   PMID:22491013   PMID:22525672   PMID:22581778   PMID:22648170  
PMID:23354168   PMID:24168030   PMID:24252604   PMID:24457600   PMID:24835466   PMID:24846918   PMID:25212232   PMID:25253241   PMID:25281401   PMID:25340657   PMID:25360623   PMID:26424600  
PMID:26507506   PMID:26927671   PMID:27005486   PMID:27313319   PMID:27398911   PMID:27417122   PMID:27586544   PMID:27748405   PMID:27779214   PMID:28087629   PMID:28226240   PMID:28387983  
PMID:29044176   PMID:29196616   PMID:29212953   PMID:29454706   PMID:29599136   PMID:29693140   PMID:29879378   PMID:29925839   PMID:30061390   PMID:30256721   PMID:30275566   PMID:30335684  
PMID:30541888   PMID:31474562   PMID:32133736   PMID:32325033   PMID:32571632   PMID:32651166   PMID:33230114  


Genomics

Comparative Map Data
Dab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,329,269 - 6,470,196 (+)NCBIGRCm39mm39
GRCm39 Ensembl156,329,269 - 6,470,193 (+)Ensembl
GRCm38156,299,788 - 6,440,715 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,299,788 - 6,440,712 (+)EnsemblGRCm38mm10GRCm38
MGSCv37156,249,789 - 6,390,712 (+)NCBIGRCm37mm9NCBIm37
MGSCv36156,247,064 - 6,387,927 (+)NCBImm8
Celera156,148,799 - 6,289,867 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map152.15NCBI
DAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl539,371,675 - 39,462,300 (-)EnsemblGRCh38hg38GRCh38
GRCh38539,371,677 - 39,424,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37539,371,779 - 39,425,082 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map5p13.1NCBI
HuRef539,323,383 - 39,377,010 (-)NCBIHuRef
CHM1_1539,373,679 - 39,427,330 (-)NCBICHM1_1
Dab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2255,514,692 - 55,567,476 (+)NCBI
Rnor_6.0 Ensembl255,747,318 - 55,768,270 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0255,747,353 - 55,768,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0275,489,435 - 75,510,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,714,874 - 55,736,370 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1255,643,109 - 55,664,600 (+)NCBI
Celera251,166,390 - 51,187,877 (+)NCBICelera
Cytogenetic Map2q16NCBI
DAB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1469,625,874 - 69,648,349 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl469,625,527 - 69,648,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha469,274,405 - 69,324,807 (+)NCBI
ROS_Cfam_1.0470,113,533 - 70,163,994 (+)NCBI
UMICH_Zoey_3.1469,862,358 - 69,913,299 (+)NCBI
UNSW_CanFamBas_1.0469,975,198 - 70,025,729 (+)NCBI
UU_Cfam_GSD_1.0470,513,789 - 70,564,779 (+)NCBI

Position Markers
Dab2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15AUniSTS
cM Map156.7UniSTS
AA960054  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38156,439,326 - 6,439,503UniSTSGRCm38
MGSCv37156,389,326 - 6,389,503UniSTSGRCm37
Celera156,288,481 - 6,288,658UniSTS
Cytogenetic Map15AUniSTS
cM Map156.7UniSTS
Whitehead/MRC_RH100.0UniSTS
AI957090  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38156,427,473 - 6,427,606UniSTSGRCm38
MGSCv37156,377,473 - 6,377,606UniSTSGRCm37
Celera156,276,636 - 6,276,769UniSTS
Cytogenetic Map15AUniSTS
cM Map156.7UniSTS
Whitehead/MRC_RH101.85UniSTS
UniSTS:225286  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38156,438,872 - 6,439,060UniSTSGRCm38
MGSCv37156,388,872 - 6,389,060UniSTSGRCm37
Celera156,288,027 - 6,288,215UniSTS
Cytogenetic Map15AUniSTS
cM Map156.7UniSTS
SGC34180  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38156,427,531 - 6,427,656UniSTSGRCm38
MGSCv37156,377,531 - 6,377,656UniSTSGRCm37
Celera156,276,694 - 6,276,819UniSTS
Cytogenetic Map15AUniSTS
cM Map156.7UniSTS
RH125668  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38156,440,386 - 6,440,635UniSTSGRCm38
MGSCv37156,390,386 - 6,390,635UniSTSGRCm37
Celera156,289,541 - 6,289,790UniSTS
Cytogenetic Map15AUniSTS
cM Map156.7UniSTS
Dab2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15AUniSTS
Dab2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15AUniSTS
Dab2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15AUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300953Bdt5_mbone density traits 5 (mouse)Not determined15120460347Mouse
1301023Sluc24_msusceptibility to lung cancer 24 (mouse)Not determined15120460347Mouse
1302121Cliff_mcliff drop aversion (mouse)Not determined15120460347Mouse
1301662Faq8_mfluctuating asymmetry QTL 8 (mouse)Not determined15120460347Mouse
5491193Mobq4_mmultigenic obesity QTL 4 (mouse)Not determined15120460347Mouse
4141541Tglq3_mtriglyceride QTL 3 (mouse)Not determined15120460347Mouse
1357459Nhdlq7_mnon-HDL QTL 7 (mouse)Not determined15120460347Mouse
11062069Bpq31_mblood pressure QTL 31 (mouse)15126273109Mouse
4141446Ffaq4_mfree fatty acid QTL 4 (mouse)Not determined127101304Mouse
1300594Eae2_msusceptibility to experimental allergic encephalomyelitis 2 (mouse)Not determined15131218650Mouse
1301136Pgia8_mproteoglycan induced arthritis 8 (mouse)Not determined15321068524388090Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15344490771325689Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined346021278717086Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined346021278717086Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined346021278717086Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15346021278717086Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15346021278717086Mouse
4141358Ath22_matherosclerosis 22 (mouse)Not determined346456637464566Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562040839620528Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15610000038000000Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15610000050900000Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15610000068400000Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15610000071600000Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15610000072600000Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15610000076000000Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15610000076500000Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15610000078800000Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15610000086800000Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156100000100900000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir187mmu-miR-187-3pOncomiRDBexternal_infoNANA21725366

Predicted Target Of
Summary Value
Count of predictions:4903
Count of miRNA genes:812
Interacting mature miRNAs:1041
Transcripts:ENSMUST00000063320, ENSMUST00000078019, ENSMUST00000080880, ENSMUST00000110663, ENSMUST00000110664, ENSMUST00000159046, ENSMUST00000159490, ENSMUST00000159552, ENSMUST00000160134, ENSMUST00000161040, ENSMUST00000161558, ENSMUST00000161812, ENSMUST00000162094, ENSMUST00000162140, ENSMUST00000163082
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001008702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001037905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001102400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001310446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF220562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH010165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ295277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB848282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB856968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG072606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB598046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB952492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD348957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD741855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000078019   ⟹   ENSMUSP00000077166
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,299,788 - 6,440,712 (+)Ensembl
RefSeq Acc Id: ENSMUST00000080880   ⟹   ENSMUSP00000079689
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,386,598 - 6,440,705 (+)Ensembl
RefSeq Acc Id: ENSMUST00000110663   ⟹   ENSMUSP00000106291
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,386,776 - 6,439,628 (+)Ensembl
RefSeq Acc Id: ENSMUST00000110664   ⟹   ENSMUSP00000106292
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,386,748 - 6,440,705 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159046   ⟹   ENSMUSP00000125452
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,299,813 - 6,416,924 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159490   ⟹   ENSMUSP00000124145
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,389,050 - 6,418,318 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159552
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,299,788 - 6,435,520 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160134   ⟹   ENSMUSP00000125021
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,386,779 - 6,427,765 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161040   ⟹   ENSMUSP00000124478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,299,832 - 6,427,765 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161558
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,423,162 - 6,425,024 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161812   ⟹   ENSMUSP00000124589
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,386,777 - 6,439,648 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162094   ⟹   ENSMUSP00000125696
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,390,120 - 6,419,837 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162140
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,299,868 - 6,337,206 (+)Ensembl
RefSeq Acc Id: ENSMUST00000163082   ⟹   ENSMUSP00000124996
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl156,422,240 - 6,438,907 (+)Ensembl
RefSeq Acc Id: NM_001008702   ⟹   NP_001008702
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,329,270 - 6,470,193 (+)NCBI
GRCm38156,299,789 - 6,440,712 (+)NCBI
MGSCv37156,249,789 - 6,390,712 (+)RGD
Celera156,148,799 - 6,289,867 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001037905   ⟹   NP_001032994
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,229 - 6,470,193 (+)NCBI
GRCm38156,386,748 - 6,440,712 (+)NCBI
MGSCv37156,249,789 - 6,390,712 (+)RGD
Celera156,148,799 - 6,289,867 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001102400   ⟹   NP_001095870
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,229 - 6,470,193 (+)NCBI
GRCm38156,386,748 - 6,440,712 (+)NCBI
MGSCv37156,249,789 - 6,390,712 (+)RGD
Celera156,148,799 - 6,289,867 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001310446   ⟹   NP_001297375
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,229 - 6,470,193 (+)NCBI
GRCm38156,386,748 - 6,440,712 (+)NCBI
Sequence:
RefSeq Acc Id: NM_023118   ⟹   NP_075607
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,229 - 6,470,193 (+)NCBI
GRCm38156,386,748 - 6,440,712 (+)NCBI
MGSCv37156,249,789 - 6,390,712 (+)RGD
Celera156,148,799 - 6,289,867 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011245324   ⟹   XP_011243626
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,329,269 - 6,470,196 (+)NCBI
GRCm38156,299,788 - 6,440,715 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316424   ⟹   XP_017171913
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,106 - 6,470,196 (+)NCBI
GRCm38156,386,388 - 6,440,715 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248312   ⟹   XP_030104172
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,123 - 6,470,193 (+)NCBI
GRCm38156,386,388 - 6,440,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248313   ⟹   XP_030104173
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,416,053 - 6,458,381 (+)NCBI
GRCm38156,386,388 - 6,428,900 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001008702   ⟸   NM_001008702
- Peptide Label: isoform b
- UniProtKB: P98078 (UniProtKB/Swiss-Prot),   Q3TN55 (UniProtKB/TrEMBL),   Q3TRE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_075607   ⟸   NM_023118
- Peptide Label: isoform a
- UniProtKB: P98078 (UniProtKB/Swiss-Prot),   A0A0R4J104 (UniProtKB/TrEMBL),   Q3TN55 (UniProtKB/TrEMBL),   Q3TRE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001032994   ⟸   NM_001037905
- Peptide Label: isoform b
- UniProtKB: P98078 (UniProtKB/Swiss-Prot),   Q3TN55 (UniProtKB/TrEMBL),   Q3TRE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001095870   ⟸   NM_001102400
- Peptide Label: isoform c
- UniProtKB: E9PX84 (UniProtKB/TrEMBL),   Q3TRI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243626   ⟸   XM_011245324
- Peptide Label: isoform X1
- UniProtKB: P98078 (UniProtKB/Swiss-Prot),   A0A0R4J104 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017171913   ⟸   XM_017316424
- Peptide Label: isoform X1
- UniProtKB: P98078 (UniProtKB/Swiss-Prot),   A0A0R4J104 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297375   ⟸   NM_001310446
- Peptide Label: isoform d
- UniProtKB: E9QL31 (UniProtKB/TrEMBL),   Q3TN55 (UniProtKB/TrEMBL),   Q3TRE6 (UniProtKB/TrEMBL),   Q3TRI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030104172   ⟸   XM_030248312
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030104173   ⟸   XM_030248313
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000125452   ⟸   ENSMUST00000159046
RefSeq Acc Id: ENSMUSP00000124145   ⟸   ENSMUST00000159490
RefSeq Acc Id: ENSMUSP00000106291   ⟸   ENSMUST00000110663
RefSeq Acc Id: ENSMUSP00000106292   ⟸   ENSMUST00000110664
RefSeq Acc Id: ENSMUSP00000124996   ⟸   ENSMUST00000163082
RefSeq Acc Id: ENSMUSP00000125021   ⟸   ENSMUST00000160134
RefSeq Acc Id: ENSMUSP00000079689   ⟸   ENSMUST00000080880
RefSeq Acc Id: ENSMUSP00000077166   ⟸   ENSMUST00000078019
RefSeq Acc Id: ENSMUSP00000125696   ⟸   ENSMUST00000162094
RefSeq Acc Id: ENSMUSP00000124478   ⟸   ENSMUST00000161040
RefSeq Acc Id: ENSMUSP00000124589   ⟸   ENSMUST00000161812
Protein Domains
PID

Promoters
RGD ID:6825909
Promoter ID:MM_KWN:17947
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000083956,   OTTMUST00000083957,   OTTMUST00000084005,   UC007VDB.1,   UC007VDC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,249,666 - 6,250,166 (+)MPROMDB
RGD ID:8683338
Promoter ID:EPDNEW_M19699
Type:initiation region
Name:Dab2_2
Description:Mus musculus disabled 2, mitogen-responsive phosphoprotein ,transcript variant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19700  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38156,299,788 - 6,299,848EPDNEW
RGD ID:6825902
Promoter ID:MM_KWN:17949
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:AK154716_DAB2,   ENSMUST00000110664,   NM_001037905,   NM_001102400,   OTTMUST00000083998,   OTTMUST00000084006
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,336,554 - 6,337,054 (+)MPROMDB
RGD ID:6825906
Promoter ID:MM_KWN:17950
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   ES_Cell,   MEF_B6
Transcripts:OTTMUST00000084003
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,338,276 - 6,338,862 (+)MPROMDB
RGD ID:6825907
Promoter ID:MM_KWN:17951
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour
Transcripts:OTTMUST00000084004
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,339,611 - 6,340,307 (+)MPROMDB
RGD ID:6825903
Promoter ID:MM_KWN:17952
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:OTTMUST00000084002
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,371,236 - 6,371,736 (+)MPROMDB
RGD ID:6825908
Promoter ID:MM_KWN:17953
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour
Transcripts:OTTMUST00000084007
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,373,284 - 6,373,784 (+)MPROMDB
RGD ID:8683340
Promoter ID:EPDNEW_M19700
Type:initiation region
Name:Dab2_1
Description:Mus musculus disabled 2, mitogen-responsive phosphoprotein ,transcript variant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19699  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38156,386,778 - 6,386,838EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109175 AgrOrtholog
Ensembl Genes ENSMUSG00000022150 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000077166 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000079689 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000106291 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000106292 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124145 UniProtKB/TrEMBL
  ENSMUSP00000124478 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124589 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124996 UniProtKB/TrEMBL
  ENSMUSP00000125021 UniProtKB/TrEMBL
  ENSMUSP00000125452 UniProtKB/TrEMBL
  ENSMUSP00000125696 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078019 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000080880 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000110663 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000110664 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000159046 UniProtKB/TrEMBL
  ENSMUST00000159490 UniProtKB/TrEMBL
  ENSMUST00000160134 UniProtKB/TrEMBL
  ENSMUST00000161040 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000161812 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000162094 UniProtKB/TrEMBL
  ENSMUST00000163082 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13132 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:109175 ENTREZGENE
NCBI Gene 13132 ENTREZGENE
Pfam PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dab2 PhenoGen
PROSITE PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J104 ENTREZGENE, UniProtKB/TrEMBL
  A0A1Y7VGS2_MOUSE UniProtKB/TrEMBL
  DAB2_MOUSE UniProtKB/Swiss-Prot
  E0CXT5_MOUSE UniProtKB/TrEMBL
  E0CYJ2_MOUSE UniProtKB/TrEMBL
  E0CZ53_MOUSE UniProtKB/TrEMBL
  E9PX84 ENTREZGENE, UniProtKB/TrEMBL
  E9QL31 ENTREZGENE, UniProtKB/TrEMBL
  F6TQN9_MOUSE UniProtKB/TrEMBL
  P98078 ENTREZGENE
  Q3TMQ2_MOUSE UniProtKB/TrEMBL
  Q3TN55 ENTREZGENE, UniProtKB/TrEMBL
  Q3TRE6 ENTREZGENE, UniProtKB/TrEMBL
  Q3TRI2 ENTREZGENE, UniProtKB/TrEMBL
  Q8C736_MOUSE UniProtKB/TrEMBL
  Q9DCE6_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3U3K1 UniProtKB/Swiss-Prot
  Q91W56 UniProtKB/Swiss-Prot
  Q923E1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Dab2  disabled 2, mitogen-responsive phosphoprotein  D630005B22Rik  RIKEN cDNA D630005B22 gene  Data Merged 737654 PROVISIONAL
2012-07-05 Dab2  disabled 2, mitogen-responsive phosphoprotein  Dab2  disabled homolog 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED