Vamp8 (vesicle-associated membrane protein 8)

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Gene: Vamp8 (vesicle-associated membrane protein 8) Mus musculus

Analyze

Symbol:

Vamp8

Name:

vesicle-associated membrane protein 8

RGD ID:

731713

MGI Page

MGI

Description:

Is expressed in ovary; primary sex cord; and retina. Orthologous to human VAMP8 (vesicle associated membrane protein 8); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

AU041171; Edb; endo; endobrevin; VAMP-8

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VAMP8 (vesicle associated membrane protein 8)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Vamp8 (vesicle-associated membrane protein 8)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Vamp8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VAMP8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	VAMP8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vamp8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VAMP8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	VAMP8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Vamp8 (vesicle associated membrane protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Vamp8 (vesicle-associated membrane protein 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	VAMP8 (vesicle associated membrane protein 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	vamp8 (vesicle-associated membrane protein 8 (endobrevin))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam\|ZFIN)
Saccharomyces cerevisiae (baker's yeast):	SNC1	Alliance	DIOPT (OMA\|PANTHER\|Roundup)
Saccharomyces cerevisiae (baker's yeast):	SNC2	Alliance	DIOPT (OMA\|PANTHER\|Roundup)
Caenorhabditis elegans (roundworm):	vamp-8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	vamp-7	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PhylomeDB\|Roundup\|TreeFam)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	72,362,204 - 72,367,650 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	72,362,206 - 72,367,686 (-)	Ensembl
GRCm38	6	72,385,221 - 72,390,667 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	72,385,223 - 72,390,703 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	72,335,215 - 72,340,661 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	72,314,732 - 72,320,090 (-)	NCBI			mm8
Celera	6	74,475,546 - 74,480,987 (-)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	32.27	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

Mammary Neoplasms, Experimental (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

2-methoxyethanol (ISO)

4,4'-sulfonyldiphenol (EXP)

5-aza-2'-deoxycytidine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (ISO)

amphetamine (ISO)

antirheumatic drug (ISO)

benzene (ISO)

benzo[a]pyrene (EXP,ISO)

bexarotene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

chloropicrin (ISO)

cisplatin (ISO)

clothianidin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

elemental selenium (ISO)

entinostat (ISO)

ethyl methanesulfonate (ISO)

folic acid (EXP)

formaldehyde (ISO)

gentamycin (ISO)

mercury dibromide (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (ISO)

paclitaxel (ISO)

panobinostat (ISO)

paracetamol (ISO)

phenethyl caffeate (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

tetrachloromethane (EXP,ISO)

toluene (ISO)

trichostatin A (ISO)

trimellitic anhydride (EXP)

valproic acid (ISO)

vinclozolin (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagosome maturation (ISO)

autophagosome membrane docking (ISO)

autophagy (IEA)

cellular response to interferon-gamma (IDA)

defense response to virus (IEA)

eosinophil degranulation (ISO)

membrane fusion (ISO)

mucus secretion (IBA,IMP,ISO)

negative regulation of secretion by cell (ISO)

neutrophil degranulation (ISO)

positive regulation of histamine secretion by mast cell (ISO)

positive regulation of pancreatic amylase secretion (IMP)

protein transport (IEA)

protein-containing complex assembly (ISO)

regulation of endocytosis (IMP)

regulation of protein localization to plasma membrane (ISO)

SNARE complex assembly (IBA,IDA)

vesicle fusion (IBA,IMP,ISO)

vesicle-mediated transport (ISO)

viral entry into host cell (ISO)

zymogen granule exocytosis (IMP)

Cellular Component

azurophil granule membrane (ISO)

basolateral plasma membrane (IDA)

cell surface (IDA)

cytoplasm (ISO)

cytosol (IDA,ISO)

early endosome (TAS)

endosome (IEA)

integral component of membrane (IEA)

late endosome membrane (ISO)

lysosomal membrane (ISO)

lysosome (IDA)

membrane (ISO)

midbody (ISO)

mitochondrion (HDA)

mucin granule (IBA,ISO)

perinuclear region of cytoplasm (ISO)

phagocytic vesicle (IDA)

plasma membrane (IBA,ISO)

recycling endosome (ISO)

secretory granule (IDA)

secretory granule membrane (ISO)

SNARE complex (IBA,IDA,ISO)

vesicle (ISO)

zymogen granule (IDA)

Molecular Function

chloride channel inhibitor activity (ISO)

protein binding (IPI,ISO)

SNAP receptor activity (IBA,ISO)

syntaxin binding (IBA,ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal circulating amylase level (IAGP)

abnormal circulating lipase level (IAGP)

abnormal dendritic cell physiology (IAGP)

abnormal enzyme/coenzyme activity (IAGP)

abnormal mast cell physiology (IAGP)

abnormal pancreas secretion (IAGP)

abnormal pancreatic acinar cell morphology (IAGP)

abnormal pancreatic acinar cell zymogen granule morphology (IAGP)

abnormal platelet activation (IAGP)

abnormal platelet physiology (IAGP)

abnormal type I hypersensitivity reaction (IAGP)

colorless urine (IAGP)

decreased mast cell degranulation (IAGP)

decreased susceptibility to induced pancreatitis (IAGP)

decreased urine osmolality (IAGP)

dilated kidney collecting duct (IAGP)

hydronephrosis (IAGP)

increased blood osmolality (IAGP)

increased circulating renin level (IAGP)

increased fluid intake (IAGP)

kidney atrophy (IAGP)

kidney degeneration (IAGP)

kidney medulla atrophy (IAGP)

pancreatic acinar cell zymogen granule accumulation (IAGP)

postnatal growth retardation (IAGP)

postnatal lethality, incomplete penetrance (IAGP)

premature death (IAGP)

References

References - curated


1.	Advani RJ, etal., J Biol Chem 1998 Apr 24;273(17):10317-24.
2.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4.	MGD data from the GO Consortium
5.	MGD IEA
6.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7.	RGD automated import pipeline
8.	RGD automated import pipeline for gene-chemical interactions
9.	Richardson SC, etal., Mol Biol Cell 2004 Mar;15(3):1197-210. Epub 2003 Dec 10.

Additional References at PubMed

PMID:9560157	PMID:9614193	PMID:9878266	PMID:10349636	PMID:10379359	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11278762	PMID:12477932	PMID:14610273	PMID:15363411
PMID:15489334	PMID:16141072	PMID:16141073	PMID:16602821	PMID:16935260	PMID:17065550	PMID:17215514	PMID:18203950	PMID:18227281	PMID:18250339	PMID:18292538	PMID:18321981
PMID:18388320	PMID:18535671	PMID:18614015	PMID:18923845	PMID:19097053	PMID:19144319	PMID:19274433	PMID:19395672	PMID:19607812	PMID:19759285	PMID:19830729	PMID:19841070
PMID:20876717	PMID:21151919	PMID:21224474	PMID:21733851	PMID:21873635	PMID:22118466	PMID:22144578	PMID:22450911	PMID:22589474	PMID:22841572	PMID:23213422	PMID:23341629
PMID:23870310	PMID:24550300	PMID:25138214	PMID:26209658	PMID:27009205	PMID:27280768	PMID:27480124	PMID:27628032	PMID:28242757	PMID:28688576	PMID:28974617	PMID:30681394

Genomics

Comparative Map Data

Vamp8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	72,362,204 - 72,367,650 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	72,362,206 - 72,367,686 (-)	Ensembl
GRCm38	6	72,385,221 - 72,390,667 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	72,385,223 - 72,390,703 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	72,335,215 - 72,340,661 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	72,314,732 - 72,320,090 (-)	NCBI			mm8
Celera	6	74,475,546 - 74,480,987 (-)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	32.27	NCBI

VAMP8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	85,561,562 - 85,582,031 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	85,577,535 - 85,582,031 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	85,804,709 - 85,809,154 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	85,658,228 - 85,662,665 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	85,716,374 - 85,720,811	NCBI
Celera	2	85,632,880 - 85,637,440 (+)	NCBI
Cytogenetic Map	2	p11.2	NCBI
HuRef	2	85,701,916 - 85,706,329 (+)	NCBI		HuRef
CHM1_1	2	85,734,420 - 85,738,962 (+)	NCBI		CHM1_1

Vamp8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	104,442,383 - 104,452,884 (-)	NCBI
Rnor_6.0 Ensembl	4	100,250,301 - 100,252,755 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	4	100,250,301 - 100,252,756 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	165,020,594 - 165,023,049 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	105,692,451 - 105,694,908 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	105,936,931 - 105,939,387 (-)	NCBI
Celera	4	93,595,511 - 93,597,967 (-)	NCBI		Celera
Cytogenetic Map	4	q31	NCBI

Vamp8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	1,923,092 - 1,926,728 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	1,922,830 - 1,926,844 (-)	NCBI	ChiLan1.0	ChiLan1.0

VAMP8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	87,180,681 - 87,185,195 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	87,180,681 - 87,185,195 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	85,627,678 - 85,632,205 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

VAMP8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	17	39,497,785 - 39,501,739 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	17	39,497,628 - 39,501,734 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Vamp8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936712	1,688,126 - 1,689,742 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VAMP8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	59,187,900 - 59,193,165 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	62,249,017 - 62,254,147 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VAMP8
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	21,575,057 - 21,580,054 (-)	NCBI
ChlSab1.1 Ensembl	14	21,575,161 - 21,579,820 (-)	Ensembl

Vamp8
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624749	17,558,429 - 17,562,765 (-)	NCBI

Position Markers

AU041171

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	72,385,338 - 72,385,482	UniSTS	GRCm38
MGSCv37	6	72,335,332 - 72,335,476	UniSTS	GRCm37
Celera	6	74,475,663 - 74,475,807	UniSTS
Cytogenetic Map	6	C1	UniSTS
cM Map	6	31.5	UniSTS
Whitehead/MRC_RH	6	721.28	UniSTS

RH101850

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	72,385,322 - 72,385,469	UniSTS	GRCm38
MGSCv37	6	72,335,316 - 72,335,463	UniSTS	GRCm37
Celera	6	74,475,647 - 74,475,794	UniSTS
Cytogenetic Map	6	C1	UniSTS
cM Map	6	31.5	UniSTS

AF053724

Mouse Assembly	Chr	Position (strand)	Source
Cytogenetic Map	6	C1	UniSTS
cM Map	6	31.5	UniSTS
Whitehead/MRC_RH	6	721.28	UniSTS

Vamp8

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	72,385,322 - 72,385,469	UniSTS	GRCm38
MGSCv37	6	72,335,316 - 72,335,463	UniSTS	GRCm37
Celera	6	74,475,647 - 74,475,794	UniSTS
Cytogenetic Map	6	C1	UniSTS
cM Map	6	31.5	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	1	117500000	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139100000	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87426034	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96656149	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96656149	Mouse
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96656149	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96656149	Mouse
26884441	Sklq3_m	skull length QTL 3, 5 week (mouse)					6	7600000	80600000	Mouse
1357442	Dbts1_m	diabetes 1 (mouse)			Not determined		6	18234148	73387692	Mouse
13208564	Bmiq7_m	body mass index QTL 7 (mouse)					6	25000000	80000000	Mouse
4141782	Mrdq5_m	modifier of retinal degeneration QTL 5 (mouse)			Not determined			32850650	78238974	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38669625	92607450	Mouse
12880424	V25Dq4_m	vitamin D inactive form serum level QTL 4 (mouse)					6	41600000	75600000	Mouse
1301266	Lmr4_m	leishmaniasis resistance 4 (mouse)			Not determined		6	42116373	76116515	Mouse
11040600	Lmr4c_m	leishmaniasis resistance 4c (mouse)					6	42116373	76116515	Mouse
11040601	Lmr4a_m	leishmaniasis resistance 4a (mouse)					6	42116373	76116515	Mouse
11533915	Mts4_m	mammary tumor susceptibility 4 (mouse)					6	42116373	76116515	Mouse
12910785	Pwgrq16_m	post-weaning growth rate QTL 16 (mouse)					6	43826813	77811523	Mouse
12910798	Pwgrq5_m	pre-weaning growth rate QTL 5 (mouse)					6	43826813	77811523	Mouse
12910802	Pwbwq12_m	post-weaning body weight QTL 12 (mouse)					6	43826813	77811523	Mouse
12910807	Pwbwq11_m	post-weaning body weight QTL 11 (mouse)					6	43826813	77811523	Mouse
12910809	Pwbwq10_m	post-weaning body weight QTL 10 (mouse)					6	43826813	77811523	Mouse
12910820	Ogrq3_m	overall growth rate QTL 3 (mouse)					6	43826813	77811523	Mouse
1300618	Pgia19_m	proteoglycan induced arthritis 19 (mouse)			Not determined		6	45314059	87426034	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45314059	128835032	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46935985	136423692	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48720000	125360000	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48720000	148450000	Mouse
4140983	Srilp_m	sleep response to influenza, light phase (mouse)			Not determined			48726556	75447710	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48726556	125356785	Mouse
1301254	Skts11_m	skin tumor susceptibility 11 (mouse)			Not determined		6	51179150	85179300	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52161713	116155267	Mouse
4141028	Mclr_m	methylcholanthrene lymphoma resistance (mouse)			Not determined			54373427	88379171	Mouse
15039373	Adip28_m	adiposity 28 (mouse)					6	56308211	90308211	Mouse
15039375	Bw41_m	body weight QTL 41 (mouse)					6	56308211	90308211	Mouse
1558977	Skmw10_m	skeletal muscle weight 10 (mouse)			Not determined		6	58447583	92447710	Mouse
10043972	Obq28_m	obesity QTL 28 (mouse)			Not determined		6	58540433	92540433	Mouse
1301740	Bwq2_m	body weight QTL 2 (mouse)			Not determined		6	60057680	94057799	Mouse
1301369	Im4_m	immunoregulatory 4 (mouse)			Not determined		6	63484738	97484905	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66713869	100714031	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70425898	104426034	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70425898	104426034	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70425898	104426034	Mouse
4141990	Etax6_m	ethanol induced ataxia 6 (mouse)			Not determined			71322621	86275719	Mouse
1302020	Bbaa20_m	B.burgdorferi-associated arthritis 20 (mouse)			Not determined		6	71322621	93464093	Mouse
1300869	Stheal5_m	soft tissue heal 5 (mouse)			Not determined		6	71575060	105575178	Mouse
1300954	Fcsa1_m	femoral cross-sectional area 1 (mouse)			Not determined		6	71981024	105981170	Mouse
1301521	Pas1c_m	pulmonary adenoma susceptibility 1c (mouse)			Not determined		6	71981024	105981170	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	368
Count of miRNA genes:	299
Interacting mature miRNAs:	323
Transcripts:	ENSMUST00000059983, ENSMUST00000142613
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_016794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC116115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF045661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF053724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH010688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK004178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK013279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC012668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC043928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000059983 ⟹ ENSMUSP00000059501

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	72,385,223 - 72,390,703 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000142613 ⟹ ENSMUSP00000145955

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	72,385,228 - 72,389,911 (-)	Ensembl

RefSeq Acc Id:

NM_016794 ⟹ NP_058074

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	72,362,204 - 72,367,650 (-)	NCBI
GRCm38	6	72,385,221 - 72,390,667 (-)	ENTREZGENE
MGSCv37	6	72,335,215 - 72,340,661 (-)	RGD
Celera	6	74,475,546 - 74,480,987 (-)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

GCAGCAGAGGGCAGCCGCCTACCTGGAGAAACCTGCAGTTACGTGTGTGGCAGGAGCCGGAGTG
GCTGGAGTCGCGGGATGGTCAGGAGGCGGGCTGAAAGTTGGAGTAAGCAGGAAGTGAAGCTGTG
GCTGCCTTGGGTGGAAACAGACTAGGCGAAGTTCTGCTTTGAGAGGCCCAAGTGCTCCGAGACA
TGGAGGAGGCCAGTGGGAGTGCCGGAAATGACCGAGTTAGGAACCTGCAGAGTGAGGTGGAGGG
AGTCAAGAATATTATGACCCAGAATGTGGAGCGGATCTTGGCCAGAGGGGAGAACCTGGACCAC
CTCCGAAACAAGACAGAGGACTTGGAAGCCACGTCTGAACACTTCAAGACAACGTCCCAGAAGG
TGGCCCGGAAGTTCTGGTGGAAGAATGTGAAGATGATTGTCATCATCTGTGTGATTGTCCTTAT
CATCGTCATCCTCATTATACTTTTTGCCACTGGTACCATCCCCACTTAAGAGTCCCTTCCATCC
CACCCTACTCCTCAGGGGTGACCTCCCTAATATGTGCCAAGAGGAGCCCTCTCCTGTCCTCCTC
CACCCAAGTGCTGCTCAGTCCCTGTGAGGGCCTTCTGCTGCATCAGATGCCCCAGACGCACCTT
GATCCCCTGGGAGGAGACAGCTGGACTGTAGCTGCATCTCATGGTCCTGAGAGTGGGTTACAGA
GACCCAGAGGACCCTGTCTGTGGCTGGGAAACTGTTGGTGGCTGGTGGGCAATAAAGACCTCTT
GGTATCCCTAAGTGTACG

hide sequence

Protein Sequences


Protein RefSeqs	NP_058074	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC06371	(Get FASTA)	NCBI Sequence Viewer
	AAC23665	(Get FASTA)	NCBI Sequence Viewer
	AAH12668	(Get FASTA)	NCBI Sequence Viewer
	AAK48423	(Get FASTA)	NCBI Sequence Viewer
	BAB21977	(Get FASTA)	NCBI Sequence Viewer
	BAB28766	(Get FASTA)	NCBI Sequence Viewer
	BAE43163	(Get FASTA)	NCBI Sequence Viewer
	EDK98979	(Get FASTA)	NCBI Sequence Viewer
	EDK98980	(Get FASTA)	NCBI Sequence Viewer
	O70404	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_058074 ⟸ NM_016794
- UniProtKB:	O70404 (UniProtKB/Swiss-Prot), A0A0R4J0R1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEASGSAGNDRVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQK VARKFWWKNVKMIVIICVIVLIIVILIILFATGTIPT hide sequence

RefSeq Acc Id:

ENSMUSP00000059501 ⟸ ENSMUST00000059983

RefSeq Acc Id:

ENSMUSP00000145955 ⟸ ENSMUST00000142613

Protein Domains

v-SNARE coiled-coil homology

Promoters

RGD ID:

6840144

Promoter ID:

MM_KWN:46461

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, Kidney, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000054391

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	72,338,276 - 72,340,437 (-)	MPROMDB

RGD ID:

6840143

Promoter ID:

MM_KWN:46462

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_2Hour, BoneMarrow_4Hour, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6

Transcripts:

OTTMUST00000054390

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	72,340,476 - 72,341,402 (-)	MPROMDB

RGD ID:

6890016

Promoter ID:

EPDNEW_M8459

Type:

initiation region

Name:

Vamp8_1

Description:

Mus musculus vesicle-associated membrane protein 8 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	72,390,631 - 72,390,691	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1336882	AgrOrtholog
Ensembl Genes	ENSMUSG00000050732	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000059501	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUSP00000145955	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000059983	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUST00000142613	UniProtKB/TrEMBL
InterPro	Synaptobrevin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Synaptobrevin/VAMP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	V_SNARE_CC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:22320	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1336882	ENTREZGENE
NCBI Gene	22320	ENTREZGENE
PANTHER	PTHR45701	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Synaptobrevin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Vamp8	PhenoGen
PIRSF	Synaptobrevin_euk	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	SYNAPTOBREVN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	SYNAPTOBREVIN	UniProtKB/TrEMBL
	V_SNARE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0R4J0R1	ENTREZGENE, UniProtKB/TrEMBL
	A0A0U1RPE8_MOUSE	UniProtKB/TrEMBL
	O70404	ENTREZGENE
	Q3V4C2_MOUSE	UniProtKB/TrEMBL
	VAMP8_MOUSE	UniProtKB/Swiss-Prot
UniProt Secondary	Q9CRA3	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD