Vamp8 (vesicle-associated membrane protein 8) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Vamp8 (vesicle-associated membrane protein 8) Mus musculus
Analyze
Symbol: Vamp8
Name: vesicle-associated membrane protein 8
RGD ID: 731713
MGI Page MGI
Description: Is expressed in ovary; primary sex cord; and retina. Orthologous to human VAMP8 (vesicle associated membrane protein 8); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU041171; Edb; endo; endobrevin; VAMP-8
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,362,204 - 72,367,650 (-)NCBIGRCm39mm39
GRCm39 Ensembl672,362,206 - 72,367,686 (-)Ensembl
GRCm38672,385,221 - 72,390,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,385,223 - 72,390,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv37672,335,215 - 72,340,661 (-)NCBIGRCm37mm9NCBIm37
MGSCv36672,314,732 - 72,320,090 (-)NCBImm8
Celera674,475,546 - 74,480,987 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Additional References at PubMed
PMID:9560157   PMID:9614193   PMID:9878266   PMID:10349636   PMID:10379359   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11278762   PMID:12477932   PMID:14610273   PMID:15363411  
PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16935260   PMID:17065550   PMID:17215514   PMID:18203950   PMID:18227281   PMID:18250339   PMID:18292538   PMID:18321981  
PMID:18388320   PMID:18535671   PMID:18614015   PMID:18923845   PMID:19097053   PMID:19144319   PMID:19274433   PMID:19395672   PMID:19607812   PMID:19759285   PMID:19830729   PMID:19841070  
PMID:20876717   PMID:21151919   PMID:21224474   PMID:21733851   PMID:21873635   PMID:22118466   PMID:22144578   PMID:22450911   PMID:22589474   PMID:22841572   PMID:23213422   PMID:23341629  
PMID:23870310   PMID:24550300   PMID:25138214   PMID:26209658   PMID:27009205   PMID:27280768   PMID:27480124   PMID:27628032   PMID:28242757   PMID:28688576   PMID:28974617   PMID:30681394  


Genomics

Comparative Map Data
Vamp8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,362,204 - 72,367,650 (-)NCBIGRCm39mm39
GRCm39 Ensembl672,362,206 - 72,367,686 (-)Ensembl
GRCm38672,385,221 - 72,390,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,385,223 - 72,390,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv37672,335,215 - 72,340,661 (-)NCBIGRCm37mm9NCBIm37
MGSCv36672,314,732 - 72,320,090 (-)NCBImm8
Celera674,475,546 - 74,480,987 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.27NCBI
VAMP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl285,561,562 - 85,582,031 (+)EnsemblGRCh38hg38GRCh38
GRCh38285,577,535 - 85,582,031 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37285,804,709 - 85,809,154 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36285,658,228 - 85,662,665 (+)NCBINCBI36hg18NCBI36
Build 34285,716,374 - 85,720,811NCBI
Celera285,632,880 - 85,637,440 (+)NCBI
Cytogenetic Map2p11.2NCBI
HuRef285,701,916 - 85,706,329 (+)NCBIHuRef
CHM1_1285,734,420 - 85,738,962 (+)NCBICHM1_1
Vamp8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24104,442,383 - 104,452,884 (-)NCBI
Rnor_6.0 Ensembl4100,250,301 - 100,252,755 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04100,250,301 - 100,252,756 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04165,020,594 - 165,023,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,692,451 - 105,694,908 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14105,936,931 - 105,939,387 (-)NCBI
Celera493,595,511 - 93,597,967 (-)NCBICelera
Cytogenetic Map4q31NCBI
Vamp8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554241,923,092 - 1,926,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554241,922,830 - 1,926,844 (-)NCBIChiLan1.0ChiLan1.0
VAMP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A87,180,681 - 87,185,195 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A87,180,681 - 87,185,195 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A85,627,678 - 85,632,205 (+)NCBIMhudiblu_PPA_v0panPan3
VAMP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1739,497,785 - 39,501,739 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11739,497,628 - 39,501,734 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Vamp8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367121,688,126 - 1,689,742 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VAMP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1359,187,900 - 59,193,165 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2362,249,017 - 62,254,147 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VAMP8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,575,057 - 21,580,054 (-)NCBI
ChlSab1.1 Ensembl1421,575,161 - 21,579,820 (-)Ensembl
Vamp8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474917,558,429 - 17,562,765 (-)NCBI

Position Markers
AU041171  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,385,338 - 72,385,482UniSTSGRCm38
MGSCv37672,335,332 - 72,335,476UniSTSGRCm37
Celera674,475,663 - 74,475,807UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6721.28UniSTS
RH101850  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,385,322 - 72,385,469UniSTSGRCm38
MGSCv37672,335,316 - 72,335,463UniSTSGRCm37
Celera674,475,647 - 74,475,794UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
AF053724  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6721.28UniSTS
Vamp8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,385,322 - 72,385,469UniSTSGRCm38
MGSCv37672,335,316 - 72,335,463UniSTSGRCm37
Celera674,475,647 - 74,475,794UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3285065078238974Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64160000075600000Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64211637376116515Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64211637376116515Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64211637376116515Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64211637376116515Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64382681377811523Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64382681377811523Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64382681377811523Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64382681377811523Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64382681377811523Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64382681377811523Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4872655675447710Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:368
Count of miRNA genes:299
Interacting mature miRNAs:323
Transcripts:ENSMUST00000059983, ENSMUST00000142613
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000059983   ⟹   ENSMUSP00000059501
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl672,385,223 - 72,390,703 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142613   ⟹   ENSMUSP00000145955
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl672,385,228 - 72,389,911 (-)Ensembl
RefSeq Acc Id: NM_016794   ⟹   NP_058074
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39672,362,204 - 72,367,650 (-)NCBI
GRCm38672,385,221 - 72,390,667 (-)ENTREZGENE
MGSCv37672,335,215 - 72,340,661 (-)RGD
Celera674,475,546 - 74,480,987 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058074   ⟸   NM_016794
- UniProtKB: O70404 (UniProtKB/Swiss-Prot),   A0A0R4J0R1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059501   ⟸   ENSMUST00000059983
RefSeq Acc Id: ENSMUSP00000145955   ⟸   ENSMUST00000142613
Promoters
RGD ID:6840144
Promoter ID:MM_KWN:46461
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000054391
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36672,338,276 - 72,340,437 (-)MPROMDB
RGD ID:6840143
Promoter ID:MM_KWN:46462
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000054390
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36672,340,476 - 72,341,402 (-)MPROMDB
RGD ID:6890016
Promoter ID:EPDNEW_M8459
Type:initiation region
Name:Vamp8_1
Description:Mus musculus vesicle-associated membrane protein 8 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38672,390,631 - 72,390,691EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1336882 AgrOrtholog
Ensembl Genes ENSMUSG00000050732 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000059501 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000145955 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000059983 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000142613 UniProtKB/TrEMBL
InterPro Synaptobrevin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synaptobrevin/VAMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V_SNARE_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22320 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1336882 ENTREZGENE
NCBI Gene 22320 ENTREZGENE
PANTHER PTHR45701 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Synaptobrevin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vamp8 PhenoGen
PIRSF Synaptobrevin_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS SYNAPTOBREVN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SYNAPTOBREVIN UniProtKB/TrEMBL
  V_SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0R1 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RPE8_MOUSE UniProtKB/TrEMBL
  O70404 ENTREZGENE
  Q3V4C2_MOUSE UniProtKB/TrEMBL
  VAMP8_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9CRA3 UniProtKB/Swiss-Prot