Gosr1 (golgi SNAP receptor complex member 1) - Rat Genome Database

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Gene: Gosr1 (golgi SNAP receptor complex member 1) Mus musculus
Analyze
Symbol: Gosr1
Name: golgi SNAP receptor complex member 1
RGD ID: 737607
MGI Page MGI
Description: Predicted to enable SNAP receptor activity. Predicted to be involved in Golgi vesicle transport; retrograde transport, endosome to Golgi; and vesicle fusion. Located in Golgi membrane. Orthologous to human GOSR1 (golgi SNAP receptor complex member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 28 kDa cis-Golgi SNARE p28; 28 kDa Golgi SNARE protein; AI414660; AI426320; BB145494; Cis-Golgi SNARE; GOS-; GOS-28; GOSRI; GS2; GS28
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18727  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,617,428 - 76,654,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,617,428 - 76,654,405 (-)EnsemblGRCm39 Ensembl
GRCm381176,726,602 - 76,763,578 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,726,602 - 76,763,579 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,540,104 - 76,577,057 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,542,797 - 76,579,750 (-)NCBIMGSCv36mm8
Celera1184,231,593 - 84,268,518 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28. Sagiv Y, etal., EMBO J 2000 Apr 3;19(7):1494-504.
Additional References at PubMed
PMID:9705316   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11323436   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15728249   PMID:16141072   PMID:16141073  
PMID:21677750   PMID:21873635   PMID:22794259   PMID:29437892   PMID:30550785   PMID:32554809   PMID:32968282  


Genomics

Comparative Map Data
Gosr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,617,428 - 76,654,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,617,428 - 76,654,405 (-)EnsemblGRCm39 Ensembl
GRCm381176,726,602 - 76,763,578 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,726,602 - 76,763,579 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,540,104 - 76,577,057 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,542,797 - 76,579,750 (-)NCBIMGSCv36mm8
Celera1184,231,593 - 84,268,518 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.02NCBI
GOSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381730,477,408 - 30,527,592 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1730,477,362 - 30,527,592 (+)EnsemblGRCh38hg38GRCh38
GRCh371728,804,426 - 28,854,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361725,828,552 - 25,877,958 (+)NCBINCBI36Build 36hg18NCBI36
Build 341725,828,551 - 25,877,957NCBI
Celera1725,665,931 - 25,715,342 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1725,014,453 - 25,063,857 (+)NCBIHuRef
CHM1_11728,866,903 - 28,916,561 (+)NCBICHM1_1
T2T-CHM13v2.01731,422,038 - 31,472,230 (+)NCBIT2T-CHM13v2.0
Gosr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81062,068,662 - 62,105,442 (-)NCBIGRCr8
mRatBN7.21061,570,499 - 61,607,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1061,450,494 - 61,607,177 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1061,450,494 - 61,607,177 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1066,217,723 - 66,252,823 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,723,193 - 65,758,294 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01061,192,382 - 61,227,666 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01063,405,526 - 63,442,257 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1063,405,586 - 63,442,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,104,203 - 63,140,932 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41067,407,203 - 67,442,601 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11067,420,825 - 67,456,224 (+)NCBI
Celera1060,583,884 - 60,619,004 (-)NCBICelera
Cytogenetic Map10q24NCBI
Gosr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,831,118 - 2,876,756 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,831,118 - 2,876,756 (-)NCBIChiLan1.0ChiLan1.0
GOSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21933,923,441 - 33,975,228 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11735,804,125 - 35,855,894 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01726,248,771 - 26,293,872 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11726,769,855 - 26,813,775 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1726,769,855 - 26,813,775 (-)Ensemblpanpan1.1panPan2
GOSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1944,478,826 - 44,537,405 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl944,478,949 - 44,532,170 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha943,630,206 - 43,687,357 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0945,296,378 - 45,353,553 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl945,296,108 - 45,367,950 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1944,076,318 - 44,133,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0944,362,740 - 44,419,640 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0944,449,010 - 44,506,170 (+)NCBIUU_Cfam_GSD_1.0
Gosr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560243,583,649 - 43,629,206 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365386,461,584 - 6,508,603 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365386,461,676 - 6,505,967 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GOSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1246,541,229 - 46,597,071 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11246,541,124 - 46,597,075 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21248,630,970 - 48,684,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GOSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11624,206,226 - 24,256,628 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1624,206,296 - 24,254,812 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660755,796,728 - 5,853,563 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gosr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247862,952,315 - 3,000,952 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gosr1
1276 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1557
Count of miRNA genes:709
Interacting mature miRNAs:901
Transcripts:ENSMUST00000010536, ENSMUST00000137767
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse

Markers in Region
BB145494  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,728,590 - 76,728,670UniSTSGRCm38
MGSCv371176,542,092 - 76,542,172UniSTSGRCm37
Celera1184,233,582 - 84,233,662UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH11960.71UniSTS
AI414660  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,727,030 - 76,727,117UniSTSGRCm38
MGSCv371176,540,532 - 76,540,619UniSTSGRCm37
Celera1184,232,021 - 84,232,108UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH11959.28UniSTS
AF079901  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,729,842 - 76,729,959UniSTSGRCm38
MGSCv371176,543,344 - 76,543,461UniSTSGRCm37
Celera1184,234,834 - 84,234,951UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH11962.33UniSTS
AI426320  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,726,781 - 76,726,861UniSTSGRCm38
MGSCv371176,540,283 - 76,540,363UniSTSGRCm37
Celera1184,231,772 - 84,231,852UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH11962.33UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000010536   ⟹   ENSMUSP00000010536
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,617,428 - 76,654,405 (-)Ensembl
GRCm38.p6 Ensembl1176,726,602 - 76,763,579 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137767
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,639,334 - 76,654,393 (-)Ensembl
GRCm38.p6 Ensembl1176,748,508 - 76,763,567 (-)Ensembl
RefSeq Acc Id: NM_001356321   ⟹   NP_001343250
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,617,428 - 76,654,404 (-)NCBI
GRCm381176,726,602 - 76,763,578 (-)NCBI
Sequence:
RefSeq Acc Id: NM_016810   ⟹   NP_058090
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,617,428 - 76,654,404 (-)NCBI
GRCm381176,726,602 - 76,763,578 (-)NCBI
MGSCv371176,540,104 - 76,577,057 (-)RGD
Celera1184,231,593 - 84,268,518 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_058090   ⟸   NM_016810
- Peptide Label: isoform 1
- UniProtKB: Q91VU9 (UniProtKB/Swiss-Prot),   O88630 (UniProtKB/Swiss-Prot),   Q80UU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001343250   ⟸   NM_001356321
- Peptide Label: isoform 2
- UniProtKB: Q80UU0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000010536   ⟸   ENSMUST00000010536

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88630-F1-model_v2 AlphaFold O88630 1-250 view protein structure

Promoters
RGD ID:6821000
Promoter ID:MM_KWN:8574
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000014084,   OTTMUST00000014085
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,576,586 - 76,577,097 (-)MPROMDB
RGD ID:8675618
Promoter ID:EPDNEW_M15836
Type:multiple initiation site
Name:Gosr1_1
Description:Mus musculus golgi SNAP receptor complex member 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381176,763,567 - 76,763,627EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1858260 AgrOrtholog
Ensembl Genes ENSMUSG00000010392 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000010536 ENTREZGENE
  ENSMUST00000010536.9 UniProtKB/Swiss-Prot
InterPro Golgi_SNAP_su1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:53334 UniProtKB/Swiss-Prot
MGD MGI:1858260 ENTREZGENE
NCBI Gene Gosr1 ENTREZGENE
PANTHER GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21094 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-SNARE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gosr1 PhenoGen
PIRSF Golgi_SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GOSR1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q80UU0 ENTREZGENE, UniProtKB/TrEMBL
  Q91VU9 ENTREZGENE
UniProt Secondary Q91VU9 UniProtKB/Swiss-Prot