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Gene: Ttr (transthyretin) Mus musculus
Symbol: Ttr
Name: transthyretin
RGD ID: 11463
Description: Predicted to have identical protein binding activity and thyroid hormone binding activity. Predicted to be involved in purine nucleobase metabolic process. Predicted to localize to extracellular space and protein-containing complex. Is expressed in several structures, including brain; extraembryonic component; gut; retina; and urinary system. Used to study transthyretin amyloidosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyloidosis; carpal tunnel syndrome; dystransthyretinemic hyperthyroxinemia; and transthyretin amyloidosis. Orthologous to human TTR (transthyretin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA408768; AI787086; D17860; MGC107649; prea; prealbumin
Homo sapiens (human) : TTR (transthyretin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ttr (transthyretin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttr (transthyretin)
Pan paniscus (bonobo/pygmy chimpanzee) : TTR (transthyretin)
Canis lupus familiaris (dog) : TTR (transthyretin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttr (transthyretin)
Sus scrofa (pig) : TTR (transthyretin)
Chlorocebus sabaeus (African green monkey) : TTR (transthyretin)
Heterocephalus glaber (naked mole-rat) : Ttr (transthyretin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1820,665,280 - 20,674,321 (+)EnsemblGRCm38mm10GRCm38
GRCm381820,664,209 - 20,674,326 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371820,823,751 - 20,832,827 (+)NCBIGRCm37mm9NCBIm37
MGSCv361820,808,423 - 20,817,329 (+)NCBImm8
Celera1821,160,622 - 21,169,698 (+)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1811.47NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ttr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11463
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.