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Gene: Ttr (transthyretin) Mus musculus
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Symbol: Ttr
Name: transthyretin
RGD ID: 11463
Description: Predicted to have identical protein binding activity and thyroid hormone binding activity. Predicted to be involved in purine nucleobase metabolic process. Predicted to localize to extracellular space and protein-containing complex. Is expressed in several structures, including brain; extraembryonic component; gut; retina; and urinary system. Used to study transthyretin amyloidosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyloidosis; carpal tunnel syndrome; dystransthyretinemic hyperthyroxinemia; and transthyretin amyloidosis. Orthologous to human TTR (transthyretin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA408768; AI787086; D17860; MGC107649; prea; prealbumin
Orthologs:
Homo sapiens (human) : TTR (transthyretin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ttr (transthyretin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttr (transthyretin)
Pan paniscus (bonobo/pygmy chimpanzee) : TTR (transthyretin)
Canis lupus familiaris (dog) : TTR (transthyretin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttr (transthyretin)
Sus scrofa (pig) : TTR (transthyretin)
Chlorocebus sabaeus (African green monkey) : TTR (transthyretin)
Heterocephalus glaber (naked mole-rat) : Ttr (transthyretin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1820,665,280 - 20,674,321 (+)EnsemblGRCm38mm10GRCm38
GRCm381820,664,209 - 20,674,326 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371820,823,751 - 20,832,827 (+)NCBIGRCm37mm9NCBIm37
MGSCv361820,808,423 - 20,817,329 (+)NCBImm8
Celera1821,160,622 - 21,169,698 (+)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1811.47NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ttr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11463
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.