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Gene: Acvr2b (activin receptor IIB) Mus musculus
Symbol: Acvr2b
Name: activin receptor IIB
Description: ENCODES a protein that exhibits activin binding; growth factor binding; protein serine/threonine kinase activity; INVOLVED IN activation of protein kinase activity; anterior/posterior pattern specification; artery development; PARTICIPATES IN activin signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH abnormal bronchus morphology; abnormal cardiac outflow tract development; abnormal direction of heart looping; ASSOCIATED WITH Brugada syndrome (ortholog); situs inversus (ortholog); visceral heterotaxy (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog); receptor complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4',5,5'-hexachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930516B21Rik; AA432611; activin receptor type IIB; activin receptor type-2B; ACTR-IIB; ActRIIB; AI047905; AI850658; hypothetical protein LOC75114; MGC118477; RIKEN cDNA 4930516B21 gene; uncharacterized protein LOC75114
Homo sapiens (human) : ACVR2B (activin A receptor type 2B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acvr2b (activin A receptor type 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr2b (activin A receptor type 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR2B (activin A receptor type 2B)
Canis lupus familiaris (dog) : ACVR2B (activin A receptor type 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr2b (activin A receptor type 2B)
Sus scrofa (pig) : ACVR2B (activin A receptor type 2B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389119,401,583 - 119,442,148 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379119,311,619 - 119,342,633 (+)NCBIGRCm37mm9NCBIm37
MGSCv369119,251,199 - 119,282,213 (+)NCBImm8
Celera9119,872,380 - 119,903,791 (+)NCBICelera
Cytogenetic Map9 F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Acvr2b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10078
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.