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Gene: Mark1 (MAP/microtubule affinity regulating kinase 1) Mus musculus
Symbol: Mark1
Name: MAP/microtubule affinity regulating kinase 1
Description: Predicted to have several functions, including ATP binding activity; phospholipid binding activity; and protein kinase activity. Involved in establishment of mitochondrion localization and regulation of dendrite development. Predicted to localize to several cellular components, including the cytoskeleton; dendrite; and plasma membrane. Is expressed in dorsal root ganglion; facial ganglion; glossopharyngeal ganglion; and trigeminal ganglion. Orthologous to human MARK1 (microtubule affinity regulating kinase 1); INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW491150; B930025N23Rik; ELKL motif serine-threonine protein kinase 3; ELKL motif serine/threonine-protein kinase 3; Emk3; KIAA1477; MAP/microtubule affinity-regulating kinase 1; mKIAA1477; mPar-1c; Par-1c; PAR1 homolog c; serine/threonine-protein kinase MARK1
Homo sapiens (human) : MARK1 (microtubule affinity regulating kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mark1 (microtubule affinity regulating kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mark1 (microtubule affinity regulating kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MARK1 (microtubule affinity regulating kinase 1)
Canis lupus familiaris (dog) : MARK1 (microtubule affinity regulating kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mark1 (microtubule affinity regulating kinase 1)
Sus scrofa (pig) : MARK1 (microtubule affinity regulating kinase 1)
more info ...
Related Pseudogenes: Mark1-ps1   Mark1-ps2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1184,896,789 - 184,999,570 (-)Ensembl
GRCm381184,896,424 - 184,999,901 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371186,720,303 - 186,823,428 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,598,391 - 186,700,267 (-)NCBImm8
Celera1191,860,242 - 191,963,269 (-)NCBICelera
Cytogenetic Map1 H5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mark1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732242
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.