Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Agxt (alanine-glyoxylate aminotransferase) Mus musculus
Analyze
Symbol: Agxt
Name: alanine-glyoxylate aminotransferase
Description: Exhibits alanine-glyoxylate transaminase activity. Involved in Notch signaling pathway; glyoxylate metabolic process; and oxalic acid secretion. Predicted to localize to the mitochondrial matrix and peroxisomal matrix. Human ortholog(s) of this gene implicated in primary hyperoxaluria. Is expressed in liver. Orthologous to human AGXT (alanine--glyoxylate and serine--pyruvate aminotransferase); PARTICIPATES IN alanine metabolic pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AGT; Agt1; Agxt1; alanine--glyoxylate aminotransferase; alanine-glyoxylate aminotransferase 1; serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal; serine-pyruvate aminotransferase; SPT
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl193,135,240 - 93,145,421 (+)Ensembl
GRCm38193,135,240 - 93,145,421 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,031,853 - 95,041,998 (+)NCBIGRCm37mm9NCBIm37
MGSCv36194,965,651 - 94,988,099 (+)NCBImm8
Celera196,079,904 - 96,090,082 (+)NCBICelera
Cytogenetic Map1 DNCBI
cM Map147.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Agxt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736337
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.