Agxt (alanine--glyoxylate and serine--pyruvate aminotransferase) - Rat Genome Database

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Gene: Agxt (alanine--glyoxylate and serine--pyruvate aminotransferase) Ictidomys tridecemlineatus
Analyze
Symbol: Agxt
Name: alanine--glyoxylate and serine--pyruvate aminotransferase
RGD ID: 12547740
Description: ENCODES a protein that exhibits alanine-glyoxylate transaminase activity (ortholog); amino acid binding (ortholog); serine-pyruvate transaminase activity (ortholog); INVOLVED IN glycine biosynthetic process, by transamination of glyoxylate (ortholog); glyoxylate metabolic process (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN alanine metabolic pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; ASSOCIATED WITH chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); hereditary spastic paraplegia 30 (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alanine-glyoxylate aminotransferase; serine--pyruvate aminotransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,351,908 - 192,362,526 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936745857,102 - 867,477 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936745856,915 - 867,477 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Agxt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,351,908 - 192,362,526 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936745857,102 - 867,477 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936745856,915 - 867,477 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGXT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,868,824 - 240,880,500 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2240,868,824 - 240,880,502 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,808,241 - 241,819,917 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,456,835 - 241,467,210 (+)NCBINCBI36Build 36hg18NCBI36
Build 342241,528,151 - 241,538,527NCBI
Celera2235,480,100 - 235,491,174 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2233,568,172 - 233,579,109 (+)NCBIHuRef
CHM1_12241,814,212 - 241,824,586 (+)NCBICHM1_1
T2T-CHM13v2.02241,367,223 - 241,379,660 (+)NCBIT2T-CHM13v2.0
Agxt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,062,962 - 93,073,143 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,062,962 - 93,073,143 (+)EnsemblGRCm39 Ensembl
GRCm38193,135,240 - 93,145,421 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,135,240 - 93,145,421 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,031,853 - 95,041,998 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,965,651 - 94,988,099 (+)NCBIMGSCv36mm8
Celera196,079,940 - 96,090,082 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.0NCBI
Agxt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2993,675,384 - 93,685,337 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,675,384 - 93,685,336 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9102,110,940 - 102,120,893 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.09107,246,884 - 107,256,803 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.09105,603,034 - 105,612,953 (+)NCBIRnor_WKY
Rnor_6.09100,281,339 - 100,291,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,281,339 - 100,291,291 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0999,939,444 - 99,949,397 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,412,128 - 92,422,075 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1992,616,896 - 92,626,844 (+)NCBI
Celera991,210,785 - 91,220,737 (+)NCBICelera
Cytogenetic Map9q36NCBI
Agxt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542710,005 - 717,741 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955542710,506 - 720,564 (-)NCBIChiLan1.0ChiLan1.0
AGXT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B246,928,784 - 246,939,837 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,928,784 - 246,939,837 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B128,125,289 - 128,137,091 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
AGXT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12550,968,291 - 50,976,089 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,181,404 - 51,189,176 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,163,250 - 51,171,015 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,163,418 - 51,170,784 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,004,270 - 51,012,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02550,750,660 - 50,758,423 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,026,487 - 51,034,252 (+)NCBIUU_Cfam_GSD_1.0
AGXT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15139,720,612 - 139,730,736 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115139,720,648 - 139,730,737 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215157,616,991 - 157,627,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGXT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110126,933,711 - 126,943,980 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10126,933,835 - 126,944,354 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604072,444,112 - 72,454,149 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agxt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,067,201 - 5,077,525 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248475,066,356 - 5,073,538 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005339636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000007995   ⟹   ENSSTOP00000007156
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936745857,102 - 867,477 (-)Ensembl
RefSeq Acc Id: XM_005339636   ⟹   XP_005339693
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303192,351,908 - 192,362,526 (+)NCBI
SpeTri2.0NW_004936745856,915 - 867,477 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005339693 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3275709 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005339693   ⟸   XM_005339636
- UniProtKB: I3MAT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000007156   ⟸   ENSSTOT00000007995
Protein Domains
Aminotran_5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008004 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007156.2 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007995.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro Aminotrans_V_dom UniProtKB/TrEMBL
  Aminotrans_V_PyrdxlP_BS UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_small UniProtKB/TrEMBL
  SP_NH2Trfase/AEP_transaminase UniProtKB/TrEMBL
NCBI Gene Agxt ENTREZGENE
Pfam Aminotran_5 UniProtKB/TrEMBL
PIRSF SPT UniProtKB/TrEMBL
PROSITE AA_TRANSFER_CLASS_5 UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt I3MAT8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-20 Agxt  alanine--glyoxylate and serine--pyruvate aminotransferase    alanine-glyoxylate aminotransferase  Symbol and/or name change 5135510 APPROVED