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Gene: AGXT (alanine--glyoxylate and serine--pyruvate aminotransferase) Homo sapiens
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Symbol: AGXT
Name: alanine--glyoxylate and serine--pyruvate aminotransferase
Description: This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGT; AGT1; AGXT1; alanine--glyoxylate aminotransferase; alanine-glyoxylate aminotransferase; hepatic peroxisomal alanine:glyoxylate aminotransferase; L-alanine: glyoxylate aminotransferase 1; PH1; serine--pyruvate aminotransferase; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; SPAT; SPT; TLH6
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,868,824 - 240,880,500 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,808,162 - 241,818,536 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,456,835 - 241,467,210 (+)NCBINCBI36hg18NCBI36
Build 342241,528,151 - 241,538,527NCBI
Celera2235,480,100 - 235,491,174 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2233,568,172 - 233,579,109 (+)NCBIHuRef
CHM1_12241,814,212 - 241,824,586 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Genomics

Comparative Map Data
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Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on AGXT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736336
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.