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Gene: Atp4a (ATPase, H+/K+ exchanging, gastric, alpha polypeptide) Mus musculus
Symbol: Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
RGD ID: 10212
Description: Exhibits potassium:proton exchanging ATPase activity. Involved in pH reduction; regulation of proton transport; and response to drug. Localizes to plasma membrane. Orthologous to human ATP4A (ATPase H+/K+ transporting subunit alpha); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATPase, H+/K+ exchanging, alpha polypeptide; ATPase, H+/K+ transporting, alpha polypeptide; gastric H(+)/K(+) ATPase subunit alpha; H+/K+-ATPase alpha; H+K+-transporting alpha 1; potassium-transporting ATPase alpha chain 1; proton pump
Homo sapiens (human) : ATP4A (ATPase H+/K+ transporting subunit alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp4a (ATPase H+/K+ transporting subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp4a (ATPase H+/K+ transporting subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Canis lupus familiaris (dog) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp4a (ATPase H+/K+ transporting subunit alpha)
Sus scrofa (pig) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Chlorocebus sabaeus (African green monkey) : ATP4A (ATPase H+/K+ transporting subunit alpha)
Heterocephalus glaber (naked mole-rat) : Atp4a (ATPase H+/K+ transporting subunit alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl730,712,209 - 30,725,534 (+)EnsemblGRCm38mm10GRCm38
GRCm38730,712,209 - 30,725,534 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37731,497,251 - 31,510,553 (+)NCBIGRCm37mm9NCBIm37
MGSCv36730,421,112 - 30,433,944 (+)NCBImm8
Celera725,294,279 - 25,307,645 (+)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atp4a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10212
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.