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Gene: Lman1 (lectin, mannose-binding, 1) Mus musculus
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Symbol: Lman1
Name: lectin, mannose-binding, 1
Description: Predicted to have identical protein binding activity and mannose binding activity. Involved in endoplasmic reticulum organization. Localizes to several cellular components, including COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum-Golgi intermediate compartment; and sarcomere. Is expressed in pancreas epithelium. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Orthologous to human LMAN1 (lectin, mannose binding 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610020P13Rik; AI326273; AU043785; C730041J05; ER-Golgi intermediate compartment 53 kDa protein; ERGIC53; F5F8D; gp58; lectin mannose-binding 1; MCFD1; MR60; P58; protein ERGIC-53
Orthologs:
Homo sapiens (human) : LMAN1 (lectin, mannose binding 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lman1 (lectin, mannose-binding, 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lman1 (lectin, mannose binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LMAN1 (lectin, mannose binding 1)
Canis lupus familiaris (dog) : LMAN1 (lectin, mannose binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lman1 (lectin, mannose binding 1)
Sus scrofa (pig) : LMAN1 (lectin, mannose binding 1)
Chlorocebus sabaeus (African green monkey) : LMAN1 (lectin, mannose binding 1)
Heterocephalus glaber (naked mole-rat) : Lman1 (lectin, mannose binding 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1865,980,738 - 66,022,580 (-)EnsemblGRCm38mm10GRCm38
GRCm381865,980,739 - 66,002,635 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371866,140,393 - 66,162,289 (-)NCBIGRCm37mm9NCBIm37
MGSCv361866,106,123 - 66,127,980 (-)NCBImm8
Celera1867,256,677 - 67,278,706 (-)NCBICelera
Cytogenetic Map18E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lman1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732235
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.