(+)-schisandrin B multiple interactions ISO RGD:3899 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TPM4 mRNA] CTD PMID:31150632 1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of TPM4 mRNA CTD PMID:26682919 1,2-dimethylhydrazine multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TPM4 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression ISO RGD:3899 6480464 1-Naphthylisothiocyanate results in increased expression of TPM4 mRNA CTD PMID:25380136 17beta-estradiol increases expression ISO RGD:736665 6480464 Estradiol results in increased expression of TPM4 mRNA CTD PMID:20106945 17beta-estradiol multiple interactions ISO RGD:736665 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of TPM4 mRNA CTD PMID:30165855 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:3899 6480464 Tetrachlorodibenzodioxin results in decreased expression of TPM4 protein CTD PMID:16548065 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of TPM4 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3899 6480464 Tetrachlorodibenzodioxin results in increased expression of TPM4 protein CTD PMID:19201780 2,4-dinitrotoluene affects expression ISO RGD:3899 6480464 2, 4-dinitrotoluene affects the expression of TPM4 mRNA CTD PMID:21346803 2-methylcholine affects expression ISO RGD:736665 6480464 beta-methylcholine affects the expression of TPM4 mRNA CTD PMID:21179406 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:736665 6480464 tetrabromobisphenol A results in increased expression of TPM4 protein CTD PMID:30098271 3-chloropropane-1,2-diol decreases expression ISO RGD:3899 6480464 alpha-Chlorohydrin results in decreased expression of TPM4 protein CTD PMID:26597043 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736665 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of TPM4 mRNA more ... CTD PMID:28628672 4,4'-diaminodiphenylmethane increases expression ISO RGD:3899 6480464 4, 4'-diaminodiphenylmethane results in increased expression of TPM4 mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol multiple interactions ISO RGD:736665 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of TPM4 mRNA CTD PMID:28628672 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of TPM4 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine decreases expression ISO RGD:736665 6480464 Decitabine results in decreased expression of TPM4 protein CTD PMID:19294695 acetamide increases expression ISO RGD:3899 6480464 acetamide results in increased expression of TPM4 mRNA CTD PMID:31881176 acrolein multiple interactions ISO RGD:736665 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TPM4 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TPM4 mRNA CTD PMID:32699268 afimoxifene affects response to substance ISO RGD:736665 6480464 TPM4 gene affects the susceptibility to afimoxifene CTD PMID:21482774 aflatoxin B1 increases expression ISO RGD:736665 6480464 Aflatoxin B1 results in increased expression of TPM4 mRNA CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:736665 6480464 Tretinoin results in decreased expression of TPM4 mRNA CTD PMID:16140955 all-trans-retinoic acid increases expression ISO RGD:736665 6480464 Tretinoin results in increased expression of TPM4 mRNA CTD PMID:23830798 alpha-pinene multiple interactions ISO RGD:736665 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TPM4 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TPM4 mRNA CTD PMID:32699268 ammonium chloride affects expression ISO RGD:3899 6480464 Ammonium Chloride affects the expression of TPM4 mRNA CTD PMID:16483693 ampicillin increases expression ISO RGD:736665 6480464 Ampicillin results in increased expression of TPM4 mRNA CTD PMID:21632981 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl 54% Chlorine results in decreased expression of TPM4 mRNA CTD PMID:23650126 arsenous acid increases expression ISO RGD:736665 6480464 Arsenic Trioxide results in increased expression of TPM4 mRNA CTD PMID:20458559 asbestos increases expression ISO RGD:736665 6480464 Asbestos results in increased expression of TPM4 protein CTD PMID:22537621 atrazine increases expression ISO RGD:736665 6480464 Atrazine results in increased expression of TPM4 mRNA CTD PMID:22378314 benzo[a]pyrene decreases expression EXP 6480464 Benzoapyrene results in decreased expression of TPM4 mRNA CTD PMID:19770486 benzo[a]pyrene affects methylation ISO RGD:736665 6480464 Benzoapyrene affects the methylation of TPM4 5' UTR, Benzoapyrene affects the methylation of TPM4 exon CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzoapyrene results in increased expression of TPM4 mRNA CTD PMID:32417428 benzo[a]pyrene decreases methylation ISO RGD:736665 6480464 Benzoapyrene results in decreased methylation of TPM4 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:736665 6480464 Benzoapyrene results in increased expression of TPM4 mRNA CTD PMID:21871943 more ... benzo[a]pyrene multiple interactions ISO RGD:736665 6480464 [Soot co-treated with Benzoapyrene] results in increased expression of TPM4 protein modified form CTD PMID:24464499 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:736665 6480464 7 more ... CTD PMID:19150397 , PMID:20018196 benzo[a]pyrene diol epoxide I increases expression ISO RGD:736665 6480464 7 more ... CTD PMID:20382639 , PMID:26238291 bexarotene increases expression ISO RGD:3899 6480464 bexarotene results in increased expression of TPM4 mRNA CTD PMID:16648578 bisphenol A increases expression ISO RGD:3899 6480464 bisphenol A results in increased expression of TPM4 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:736665 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TPM4 mRNA CTD PMID:28628672 bisphenol A decreases expression ISO RGD:3899 6480464 bisphenol A results in decreased expression of TPM4 mRNA CTD PMID:30816183 bisphenol F multiple interactions ISO RGD:736665 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPM4 mRNA CTD PMID:28628672 bleomycin A2 increases expression ISO RGD:3899 6480464 Bleomycin results in increased expression of TPM4 protein CTD PMID:25933445 bleomycin A5 increases expression ISO RGD:736665 6480464 bleomycetin results in increased expression of TPM4 mRNA CTD PMID:21040473 buspirone decreases expression ISO RGD:3899 6480464 Buspirone results in decreased expression of TPM4 mRNA CTD PMID:24136188 butan-1-ol multiple interactions ISO RGD:736665 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TPM4 mRNA CTD PMID:29432896 cadmium atom increases expression ISO RGD:736665 6480464 Cadmium results in increased expression of TPM4 mRNA CTD PMID:24376830 cadmium dichloride decreases methylation ISO RGD:3899 6480464 Cadmium Chloride results in decreased methylation of TPM4 promoter CTD PMID:22457795 cadmium dichloride decreases expression ISO RGD:736665 6480464 Cadmium Chloride results in decreased expression of TPM4 protein CTD PMID:26220685 carbon nanotube affects expression ISO RGD:736665 6480464 Nanotubes, Carbon affects the expression of TPM4 protein CTD PMID:22001959 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of TPM4 more ... CTD PMID:20938992 cisplatin increases expression ISO RGD:736665 6480464 Cisplatin results in increased expression of TPM4 mRNA CTD PMID:27594783 cisplatin decreases expression ISO RGD:736665 6480464 Cisplatin results in decreased expression of TPM4 mRNA CTD PMID:27392435 cisplatin multiple interactions ISO RGD:736665 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of TPM4 mRNA CTD PMID:27392435 copper atom multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of TPM4 mRNA CTD PMID:15467011 copper(0) multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of TPM4 mRNA CTD PMID:15467011 copper(II) sulfate increases expression ISO RGD:736665 6480464 Copper Sulfate results in increased expression of TPM4 mRNA CTD PMID:19549813 cyclosporin A increases expression ISO RGD:736665 6480464 Cyclosporine results in increased expression of TPM4 mRNA CTD PMID:20106945 , PMID:25562108 decabromodiphenyl ether decreases expression ISO RGD:3899 6480464 decabromobiphenyl ether results in decreased expression of TPM4 mRNA CTD PMID:23640034 dexamethasone multiple interactions ISO RGD:736665 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of TPM4 mRNA more ... CTD PMID:28628672 diarsenic trioxide increases expression ISO RGD:736665 6480464 Arsenic Trioxide results in increased expression of TPM4 mRNA CTD PMID:20458559 dibutyl phthalate increases expression ISO RGD:3899 6480464 Dibutyl Phthalate results in increased expression of TPM4 mRNA CTD PMID:21266533 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of TPM4 mRNA CTD PMID:21266533 dioxygen multiple interactions EXP 6480464 [sulforafan affects the susceptibility to Oxygen] which affects the expression of TPM4 mRNA CTD PMID:30529165 diuron decreases expression ISO RGD:3899 6480464 Diuron results in decreased expression of TPM4 mRNA CTD PMID:25152437 dopamine increases expression ISO RGD:3899 6480464 Dopamine results in increased expression of TPM4 mRNA CTD PMID:21983523 dorsomorphin multiple interactions ISO RGD:736665 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 doxorubicin increases oxidation ISO RGD:3899 6480464 Doxorubicin results in increased oxidation of TPM4 protein CTD PMID:28818578 doxorubicin affects expression ISO RGD:736665 6480464 Doxorubicin affects the expression of TPM4 mRNA, Doxorubicin affects the expression of TPM4 protein CTD PMID:29385562 , PMID:29803840 enzyme inhibitor multiple interactions ISO RGD:736665 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TPM4 protein CTD PMID:23301498 fenamidone increases expression EXP 6480464 fenamidone results in increased expression of TPM4 mRNA CTD PMID:27029645 fenoldopam increases expression ISO RGD:3899 6480464 Fenoldopam results in increased expression of TPM4 mRNA CTD PMID:21983523 folic acid multiple interactions EXP 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 geldanamycin increases expression ISO RGD:736665 6480464 geldanamycin results in increased expression of TPM4 mRNA CTD PMID:26705709 gentamycin increases expression ISO RGD:3899 6480464 Gentamicins results in increased expression of TPM4 mRNA CTD PMID:22061828 glafenine increases expression ISO RGD:3899 6480464 Glafenine results in increased expression of TPM4 mRNA CTD PMID:24136188 indometacin multiple interactions ISO RGD:736665 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis4-hydroxyphenylsulfone] results in decreased expression of TPM4 mRNA more ... CTD PMID:28628672 ketamine decreases expression ISO RGD:3899 6480464 Ketamine results in decreased expression of TPM4 mRNA CTD PMID:20080153 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of TPM4 more ... CTD PMID:20938992 leflunomide increases expression ISO RGD:736665 6480464 leflunomide results in increased expression of TPM4 mRNA CTD PMID:28988120 leflunomide decreases expression ISO RGD:3899 6480464 leflunomide results in decreased expression of TPM4 mRNA CTD PMID:24136188 methylmercury chloride increases expression ISO RGD:736665 6480464 methylmercuric chloride results in increased expression of TPM4 mRNA CTD PMID:23179753 more ... methylmercury chloride multiple interactions ISO RGD:736665 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of TPM4 mRNA CTD PMID:27188386 microcystin RR decreases expression ISO RGD:736665 6480464 microcystin RR results in decreased expression of TPM4 protein CTD PMID:19111056 monosodium L-glutamate multiple interactions EXP 6480464 [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TPM4 mRNA CTD PMID:22078008 N-nitrosodiethylamine increases expression ISO RGD:3899 6480464 Diethylnitrosamine results in increased expression of TPM4 mRNA CTD PMID:19638242 N-nitrosodimethylamine increases expression ISO RGD:3899 6480464 Dimethylnitrosamine results in increased expression of TPM4 mRNA CTD PMID:25380136 N-nitrosomorpholine increases expression ISO RGD:3899 6480464 N-nitrosomorpholine results in increased expression of TPM4 protein CTD PMID:19716841 nefazodone decreases expression ISO RGD:3899 6480464 nefazodone results in decreased expression of TPM4 mRNA CTD PMID:24136188 nickel atom increases expression ISO RGD:736665 6480464 Nickel results in increased expression of TPM4 mRNA CTD PMID:24768652 , PMID:25583101 nimesulide decreases expression ISO RGD:3899 6480464 nimesulide results in decreased expression of TPM4 mRNA CTD PMID:24136188 ochratoxin A decreases expression ISO RGD:3899 6480464 ochratoxin A results in decreased expression of TPM4 protein CTD PMID:31369848 ozone multiple interactions ISO RGD:736665 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TPM4 mRNA more ... CTD PMID:32699268 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of TPM4 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:736665 6480464 Acetaminophen results in increased expression of TPM4 mRNA CTD PMID:29067470 paracetamol decreases expression ISO RGD:736665 6480464 Acetaminophen results in decreased expression of TPM4 mRNA CTD PMID:22230336 paraoxon increases expression ISO RGD:736665 6480464 Paraoxon results in increased expression of TPM4 protein CTD PMID:20931991 PCB138 multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 phenethyl isothiocyanate affects binding ISO RGD:736665 6480464 TPM4 protein binds to phenethyl isothiocyanate CTD PMID:21838287 pirinixic acid multiple interactions ISO RGD:736665 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TPM4 mRNA CTD PMID:19710929 quercetin increases expression ISO RGD:736665 6480464 Quercetin results in increased expression of TPM4 mRNA CTD PMID:21632981 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of TPM4 mRNA, resveratrol results in decreased expression of TPM4 protein CTD PMID:22610192 , PMID:25505154 rimonabant multiple interactions EXP 6480464 Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TPM4 mRNA] CTD PMID:19030233 rimonabant affects expression EXP 6480464 Rimonabant affects the expression of TPM4 mRNA CTD PMID:19030233 SB 431542 multiple interactions ISO RGD:736665 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of TPM4 mRNA CTD PMID:23221170 silver atom increases expression ISO RGD:736665 6480464 Silver results in increased expression of TPM4 mRNA CTD PMID:28959546 silver(0) increases expression ISO RGD:736665 6480464 Silver results in increased expression of TPM4 mRNA CTD PMID:28959546 Soman increases expression ISO RGD:3899 6480464 Soman results in increased expression of TPM4 mRNA CTD PMID:19281266 sulforaphane multiple interactions EXP 6480464 [sulforafan affects the susceptibility to Oxygen] which affects the expression of TPM4 mRNA CTD PMID:30529165 sunitinib decreases expression ISO RGD:736665 6480464 Sunitinib results in decreased expression of TPM4 mRNA CTD PMID:31533062 tetrachloromethane increases expression ISO RGD:3899 6480464 Carbon Tetrachloride results in increased expression of TPM4 mRNA CTD PMID:31150632 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of TPM4 mRNA CTD PMID:31919559 tetrachloromethane multiple interactions ISO RGD:3899 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TPM4 mRNA] CTD PMID:31150632 thimerosal decreases expression ISO RGD:736665 6480464 Thimerosal results in decreased expression of TPM4 mRNA CTD PMID:27188386 thioacetamide increases expression ISO RGD:3899 6480464 Thioacetamide results in increased expression of TPM4 mRNA CTD PMID:23411599 torcetrapib increases expression ISO RGD:736665 6480464 torcetrapib results in increased expression of TPM4 mRNA CTD PMID:23228038 tributylstannane decreases expression ISO RGD:736665 6480464 tributyltin analog results in decreased expression of TPM4 protein CTD PMID:31634547 trichostatin A decreases expression ISO RGD:736665 6480464 trichostatin A results in decreased expression of TPM4 mRNA, trichostatin A results in decreased expression of TPM4 protein CTD PMID:19294695 , PMID:26272509 trichostatin A affects expression ISO RGD:736665 6480464 trichostatin A affects the expression of TPM4 mRNA CTD PMID:28542535 trichostatin A multiple interactions ISO RGD:736665 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of TPM4 mRNA CTD PMID:27188386 triphenyl phosphate decreases expression ISO RGD:3899 6480464 triphenyl phosphate results in decreased expression of TPM4 mRNA CTD PMID:30589522 triphenylstannane decreases expression ISO RGD:736665 6480464 triphenyltin analog results in decreased expression of TPM4 protein CTD PMID:31634547 urethane decreases expression ISO RGD:736665 6480464 Urethane results in decreased expression of TPM4 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:736665 6480464 Valproic Acid results in increased methylation of TPM4 gene CTD PMID:29154799 vancomycin decreases expression EXP 6480464 Vancomycin results in decreased expression of TPM4 mRNA CTD PMID:18930951 vinclozolin affects expression ISO RGD:3899 6480464 vinclozolin affects the expression of TPM4 mRNA CTD PMID:19015723 vincristine increases expression ISO RGD:736665 6480464 Vincristine results in increased expression of TPM4 mRNA CTD PMID:23649840 vorinostat decreases expression ISO RGD:736665 6480464 vorinostat results in decreased expression of TPM4 mRNA CTD PMID:27188386 zinc atom decreases expression ISO RGD:3899 6480464 Zinc results in decreased expression of TPM4 mRNA CTD PMID:17074742 zinc sulfate decreases expression ISO RGD:3899 6480464 Zinc Sulfate results in decreased expression of TPM4 mRNA CTD PMID:17074742 zinc(0) decreases expression ISO RGD:3899 6480464 Zinc results in decreased expression of TPM4 mRNA CTD PMID:17074742