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Gene: Psap (prosaposin) Mus musculus
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Symbol: Psap
Name: prosaposin
Description: Exhibits G protein-coupled receptor binding activity. Involved in several processes, including animal organ development; cornified envelope assembly; and galactosylceramide catabolic process. Localizes to the cytoplasm and extracellular region. Used to study Krabbe disease and metachromatic leukodystrophy. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency and combined saposin deficiency. Is expressed in several structures, including alimentary system; craniocervical region; genitourinary system; hemolymphoid system; and respiratory system. Orthologous to human PSAP (prosaposin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI037048; SGP-1; snoRNA MBII-198; sulfated glycoprotein 1
Orthologs:
Homo sapiens (human) : PSAP (prosaposin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Psap (prosaposin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psap (prosaposin)
Pan paniscus (bonobo/pygmy chimpanzee) : PSAP (prosaposin)
Canis lupus familiaris (dog) : PSAP (prosaposin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psap (prosaposin)
Sus scrofa (pig) : PSAP (prosaposin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381060,277,628 - 60,302,600 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371059,740,376 - 59,765,348 (+)NCBIGRCm37mm9NCBIm37
MGSCv361059,673,095 - 59,697,957 (+)NCBImm8
Celera1061,374,486 - 61,399,457 (+)NCBICelera
Cytogenetic Map10 B4NCBI
cM Map1030.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Psap
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11178
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.