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Gene: Cps1 (carbamoyl-phosphate synthetase 1) Mus musculus
Symbol: Cps1
Name: carbamoyl-phosphate synthetase 1
Description: Exhibits carbamoyl-phosphate synthase (ammonia) activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; carbamoyl phosphate biosynthetic process; and cellular response to ammonia. Localizes to mitochondrion. Is expressed in alimentary system; intestine; liver; and midgut. Used to study carbamoyl phosphate synthetase I deficiency disease. Human ortholog(s) of this gene implicated in carbamoyl phosphate synthetase I deficiency disease; persistent fetal circulation syndrome; and vascular disease. Orthologous to human CPS1 (carbamoyl-phosphate synthase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4732433M03Rik; carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoyl-phosphate synthetase I; carbamoylphosphate synthetase I; CPS; CPSase I; D1Ucla3
Homo sapiens (human) : CPS1 (carbamoyl-phosphate synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cps1 (carbamoyl-phosphate synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cps1 (carbamoyl-phosphate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CPS1 (carbamoyl-phosphate synthase 1)
Canis lupus familiaris (dog) : CPS1 (carbamoyl-phosphate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cps1 (carbamoyl-phosphate synthase 1)
Sus scrofa (pig) : CPS1 (carbamoyl-phosphate synthase 1)
Chlorocebus sabaeus (African green monkey) : CPS1 (carbamoyl-phosphate synthase 1)
Heterocephalus glaber (naked mole-rat) : Cps1 (carbamoyl-phosphate synthase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl167,123,026 - 67,231,259 (+)EnsemblGRCm38mm10GRCm38
GRCm38167,122,426 - 67,231,267 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37167,169,640 - 67,277,022 (+)NCBIGRCm37mm9NCBIm37
MGSCv36167,056,235 - 67,164,475 (+)NCBImm8
Celera167,649,362 - 67,756,702 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cps1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10389
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.