Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Pno1 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PNO1 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PNO1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PNO1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of PNO1 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PNO1 mRNA | CTD | PMID:21570461 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Pno1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PNO1 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of PNO1 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | ISO | PNO1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PNO1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PNO1 mRNA | CTD | PMID:32699268 | afimoxifene | multiple interactions | ISO | PNO1 (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in increased expression of PNO1 mRNA] | CTD | PMID:21233418 | aflatoxin B1 | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of PNO1 mRNA | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PNO1 mRNA | CTD | PMID:23724009 and PMID:33167477 | alpha-pinene | multiple interactions | ISO | PNO1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PNO1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PNO1 mRNA | CTD | PMID:32699268 | amitrole | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of PNO1 mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PNO1 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PNO1 protein | CTD | PMID:33212167 | arsane | affects methylation | ISO | PNO1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PNO1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | PNO1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PNO1 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | PNO1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to PNO1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PNO1 mRNA | CTD | PMID:22228805 | bexarotene | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | bexarotene results in decreased expression of PNO1 mRNA | CTD | PMID:17178900 | bisphenol A | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PNO1 mRNA | CTD | PMID:24901218 | bisphenol A | multiple interactions | ISO | Pno1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PNO1 mRNA | CTD | PMID:36041667 | bisphenol A | affects expression | ISO | PNO1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of PNO1 mRNA | CTD | PMID:30903817 | bisphenol F | multiple interactions | ISO | Pno1 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PNO1 mRNA | CTD | PMID:36041667 | bortezomib | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of PNO1 mRNA | CTD | PMID:20977926 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of PNO1 mRNA | CTD | PMID:28472532 | cisplatin | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of PNO1 mRNA | CTD | PMID:27594783 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PNO1 mRNA | CTD | PMID:21139344 | cyclosporin A | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PNO1 mRNA | CTD | PMID:20106945 and PMID:25562108 | cylindrospermopsin | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of PNO1 mRNA | CTD | PMID:24921660 | dioxygen | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of PNO1 mRNA | CTD | PMID:26516004 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PNO1 mRNA | CTD | PMID:30529165 | ethanol | affects expression | EXP | | 6480464 | Ethanol affects the expression of PNO1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of PNO1 mRNA | CTD | PMID:23649840 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of PNO1 mRNA | CTD | PMID:34813904 | finasteride | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of PNO1 mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of PNO1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PNO1 mRNA | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | PNO1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of PNO1 protein | CTD | PMID:37730182 | gentamycin | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of PNO1 mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PNO1 protein | CTD | PMID:32959892 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of PNO1 mRNA | CTD | PMID:34813904 | methimazole | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of PNO1 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of PNO1 mRNA | CTD | PMID:23649840 | nefazodone | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of PNO1 mRNA | CTD | PMID:24136188 | nickel atom | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Nickel results in increased expression of PNO1 mRNA | CTD | PMID:24768652 | ozone | multiple interactions | ISO | PNO1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PNO1 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PNO1 mRNA | CTD | PMID:34911549 | paraquat | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of PNO1 mRNA | CTD | PMID:32680482 | perfluorononanoic acid | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of PNO1 mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PNO1 mRNA | CTD | PMID:36331819 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PNO1 mRNA | CTD | PMID:23811191 | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of PNO1 mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | ISO | PNO1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PNO1 mRNA | CTD | PMID:23557933 | silicon dioxide | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PNO1 mRNA | CTD | PMID:25895662 | sodium dichromate | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | sodium bichromate results in increased expression of PNO1 mRNA | CTD | PMID:25993096 | sulfadimethoxine | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of PNO1 mRNA | CTD | PMID:30047161 | testosterone | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Testosterone results in increased expression of PNO1 mRNA | CTD | PMID:33359661 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PNO1 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of PNO1 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Pno1 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PNO1 mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PNO1 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of PNO1 mRNA | CTD | PMID:27760801 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of PNO1 mRNA | CTD | PMID:19042947 | urethane | decreases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PNO1 mRNA | CTD | PMID:28818685 | valdecoxib | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of PNO1 mRNA | CTD | PMID:24136188 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of PNO1 mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | PNO1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PNO1 mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases expression | ISO | Pno1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of PNO1 mRNA | CTD | PMID:22615374 and PMID:23869203 | |