Ptger3 (prostaglandin E receptor 3 (subtype EP3)) - Rat Genome Database

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Gene: Ptger3 (prostaglandin E receptor 3 (subtype EP3)) Mus musculus
Analyze
Symbol: Ptger3
Name: prostaglandin E receptor 3 (subtype EP3)
RGD ID: 731379
MGI Page MGI
Description: Enables prostaglandin E receptor activity. Involved in positive regulation of fever generation. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; bicarbonate transport; and fever generation. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human PTGER3 (prostaglandin E receptor 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EP; EP3; PGE receptor EP3 subtype; PGE2 receptor EP3 subtype; Pger; Pgerep3; prostaglandin E receptor EP3 subtype; prostaglandin E2 receptor EP3 subtype; prostanoid EP3 receptor; Ptger; Ptgerep3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,272,459 - 157,350,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3157,272,529 - 157,351,525 (+)EnsemblGRCm39 Ensembl
GRCm383157,566,821 - 157,644,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3157,566,892 - 157,645,888 (+)EnsemblGRCm38mm10GRCm38
MGSCv373157,229,856 - 157,307,722 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363157,502,185 - 157,580,051 (+)NCBIMGSCv36mm8
Celera3164,034,893 - 164,113,113 (+)NCBICelera
Cytogenetic Map3H4NCBI
cM Map381.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-D  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
3',5'-cyclic AMP  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
arsenite(3-)  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calciol  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP)
celecoxib  (ISO)
chlordecone  (EXP)
choline  (EXP)
ciglitazone  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diethylstilbestrol  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
eugenol  (ISO)
excitatory amino acid agonist  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (EXP,ISO)
genistein  (EXP,ISO)
glafenine  (ISO)
GW 4064  (EXP)
heptachlor  (ISO)
ibuprofen  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
methapyrilene  (ISO)
mifepristone  (ISO)
misoprostol  (EXP)
monosodium L-glutamate  (EXP)
N-nitrosodiethylamine  (ISO)
nickel sulfate  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
pristane  (EXP)
progesterone  (ISO)
prostaglandin E2  (EXP,ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rofecoxib  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
Soman  (ISO)
staurosporine  (ISO)
sulforaphane  (EXP)
sulprostone  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
terbinafine  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
Tributyltin oxide  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vinyl carbamate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IBA)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (IDA)
bicarbonate transport  (IMP)
cellular response to forskolin  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to lipopolysaccharide  (ISO)
desensitization of G protein-coupled receptor signaling pathway  (ISO)
female pregnancy  (ISO)
fever generation  (IDA,IMP)
G protein-coupled receptor signaling pathway  (IDA)
inflammatory response  (IBA)
intestine smooth muscle contraction  (IBA,ISO)
maternal process involved in parturition  (ISO)
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway  (ISO)
negative regulation of calcium ion transmembrane transport  (ISO)
negative regulation of circadian sleep/wake cycle, wakefulness  (ISO)
negative regulation of forebrain neuron differentiation  (ISO)
negative regulation of gastric acid secretion  (IBA)
negative regulation of gastrin-induced gastric acid secretion  (ISO)
negative regulation of insulin secretion  (ISO)
negative regulation of norepinephrine secretion  (ISO)
negative regulation of potassium ion transmembrane transport  (ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IBA,IDA)
positive regulation of cAMP-mediated signaling  (ISO)
positive regulation of circadian sleep/wake cycle, non-REM sleep  (ISO)
positive regulation of colon smooth muscle contraction  (ISO)
positive regulation of cytosolic calcium ion concentration  (IBA,IDA,ISO)
positive regulation of fever generation  (IMP)
positive regulation of gastric mucosal blood circulation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of inhibitory G protein-coupled receptor phosphorylation  (ISO)
positive regulation of miRNA transcription  (IDA)
positive regulation of myofibroblast contraction  (ISO)
positive regulation of neutrophil extravasation  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of smooth muscle contraction involved in micturition  (ISO)
positive regulation of urine volume  (IMP)
positive regulation of vasoconstriction  (ISO)
prostaglandin receptor internalization  (ISO)
receptor internalization  (ISO)
regulation of circadian sleep/wake cycle, wakefulness  (ISO)
regulation of norepinephrine secretion  (ISO)
response to estradiol  (ISO)
response to lipopolysaccharide  (IMP)
response to progesterone  (ISO)
response to salt  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)
urinary bladder smooth muscle contraction  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors. Ahluwalia A and Perretti M, J Pharmacol Exp Ther. 1994 Mar;268(3):1526-31.
2. The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach. Araki H, etal., Aliment Pharmacol Ther. 2000 Apr;14 Suppl 1:116-24.
3. Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
4. 16,16-Dimethyl prostaglandin E2 inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptors. Kunikata T, etal., Dig Dis Sci. 2002 Apr;47(4):894-904.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Possible involvement of the locus coeruleus in inhibition by prostanoid EP(3) receptor-selective agonists of morphine withdrawal syndrome in rats. Nakagawa T, etal., Eur J Pharmacol. 2000 Mar 3;390(3):257-66.
9. Spinal prostaglandins facilitate exaggerated A- and C-fiber-mediated reflex responses and are critical to the development of allodynia early after L5-L6 spinal nerve ligation. O'Rielly DD and Loomis CW, Anesthesiology. 2007 Apr;106(4):795-805.
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Cyclooxygenase-2 in human and experimental ischemic proliferative retinopathy. Sennlaub F, etal., Circulation. 2003 Jul 15;108(2):198-204. Epub 2003 Jun 23.
15. Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development. Shoji Y, etal., Gut. 2004 Aug;53(8):1151-8.
16. Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum. Slawik H, etal., Neurochem Int. 2004 Oct;45(5):653-60.
17. Renal cortical regulation of COX-1 and functionally related products in early renovascular hypertension (rat). Theilig F, etal., Am J Physiol Renal Physiol. 2006 Nov;291(5):F987-94. Epub 2006 Jun 20.
18. Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. Ushikubi F, etal., Nature 1998 Sep 17;395(6699):281-4.
19. COX-2 inhibition and prostaglandin receptors in experimental nephritis. Waldner C, etal., Eur J Clin Invest. 2003 Nov;33(11):969-75.
20. DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids. Wei T, etal., BMC Womens Health. 2007 Apr 2;7:5.
21. Elevation of both cyclooxygenase-2 and prostaglandin E2 receptor EP3 expressions in rat placenta after uterine artery ischemia-reperfusion. Yamazaki K, etal., Placenta. 2006 Apr-May;27(4-5):395-401. Epub 2005 Jun 28.
22. Effects of the prostanoid EP3-receptor agonists M&B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat. Zacharowski K, etal., Br J Pharmacol. 1999 Feb;126(4):849-58.
23. Adenosine A(1) and prostaglandin E receptor 3 receptors mediate global airway contraction after local epithelial injury. Zhou J, etal., Am J Respir Cell Mol Biol. 2013 Mar;48(3):299-305. doi: 10.1165/rcmb.2012-0174OC. Epub 2012 Dec 6.
Additional References at PubMed
PMID:1372606   PMID:2788176   PMID:7515568   PMID:7732847   PMID:7733888   PMID:7870313   PMID:7910583   PMID:7945376   PMID:8076637   PMID:8135729   PMID:8203567   PMID:8223569  
PMID:8307176   PMID:8381413   PMID:8396726   PMID:8567630   PMID:8833158   PMID:9116135   PMID:9124591   PMID:9348184   PMID:9606417   PMID:9843913   PMID:10508233   PMID:10535876  
PMID:10537280   PMID:10593166   PMID:10749873   PMID:11123248   PMID:11208722   PMID:11238561   PMID:11375261   PMID:11533709   PMID:11535576   PMID:11602631   PMID:11782353   PMID:11809702  
PMID:11927615   PMID:11966527   PMID:12208866   PMID:12370397   PMID:12477932   PMID:12538661   PMID:12604682   PMID:12618422   PMID:12637575   PMID:12642666   PMID:12740571   PMID:12837930  
PMID:14632179   PMID:14681479   PMID:14699136   PMID:15113745   PMID:15240726   PMID:15372104   PMID:15719070   PMID:15806106   PMID:15834430   PMID:15843564   PMID:15925391   PMID:15943039  
PMID:15976003   PMID:15983244   PMID:16051640   PMID:16230392   PMID:16237060   PMID:16247016   PMID:16446378   PMID:16602821   PMID:16877408   PMID:16954344   PMID:17003499   PMID:17075575  
PMID:17158345   PMID:17242161   PMID:17307874   PMID:17535900   PMID:17676060   PMID:17706357   PMID:17767353   PMID:17928639   PMID:18230618   PMID:18292084   PMID:18474230   PMID:18508878  
PMID:18815228   PMID:18996575   PMID:19019835   PMID:19203800   PMID:19318087   PMID:19609495   PMID:19635910   PMID:19799610   PMID:19940926   PMID:19966781   PMID:20110411   PMID:20566843  
PMID:21236356   PMID:21311040   PMID:21444662   PMID:21460251   PMID:21666791   PMID:21803432   PMID:21873635   PMID:22110249   PMID:22421267   PMID:22442093   PMID:22522619   PMID:22573380  
PMID:22615395   PMID:22967998   PMID:23065824   PMID:23349487   PMID:23485965   PMID:23595951   PMID:23624557   PMID:23922752   PMID:24036040   PMID:24342806   PMID:24923772   PMID:25054560  
PMID:25080527   PMID:25271626   PMID:25664856   PMID:25847406   PMID:26018088   PMID:26255103   PMID:26485614   PMID:26690700   PMID:26995650   PMID:27084388   PMID:27377173   PMID:27436752  
PMID:27482714   PMID:27484807   PMID:27502370   PMID:27711210   PMID:28131828   PMID:28165064   PMID:28254818   PMID:28256515   PMID:28439006   PMID:28827689   PMID:28874785   PMID:30038227  
PMID:30481825   PMID:31129913   PMID:31544253   PMID:31688905   PMID:32079648   PMID:32112485   PMID:32142358   PMID:33197428   PMID:33941650   PMID:34147480   PMID:34229444   PMID:34626853  
PMID:35037469   PMID:35203267   PMID:35420633   PMID:35781818   PMID:36087809   PMID:36245399   PMID:36317965   PMID:37171267  


Genomics

Comparative Map Data
Ptger3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,272,459 - 157,350,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3157,272,529 - 157,351,525 (+)EnsemblGRCm39 Ensembl
GRCm383157,566,821 - 157,644,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3157,566,892 - 157,645,888 (+)EnsemblGRCm38mm10GRCm38
MGSCv373157,229,856 - 157,307,722 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363157,502,185 - 157,580,051 (+)NCBIMGSCv36mm8
Celera3164,034,893 - 164,113,113 (+)NCBICelera
Cytogenetic Map3H4NCBI
cM Map381.32NCBI
PTGER3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38170,852,358 - 71,047,816 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl170,852,353 - 71,047,816 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,318,041 - 71,513,499 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,090,624 - 71,286,079 (-)NCBINCBI36Build 36hg18NCBI36
Build 34171,188,848 - 71,225,512NCBI
Celera169,607,257 - 69,802,711 (-)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef169,428,653 - 69,623,748 (-)NCBIHuRef
CHM1_1171,432,956 - 71,628,842 (-)NCBICHM1_1
T2T-CHM13v2.0170,730,386 - 70,925,810 (-)NCBIT2T-CHM13v2.0
Ptger3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22246,606,131 - 246,750,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2246,606,183 - 246,684,434 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2254,318,634 - 254,403,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02252,212,449 - 252,296,915 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02247,184,945 - 247,269,307 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02263,895,093 - 263,979,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2263,895,241 - 263,979,698 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02282,614,936 - 282,760,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42255,680,691 - 255,759,202 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12255,695,297 - 255,773,809 (+)NCBI
Celera2238,415,230 - 238,493,209 (+)NCBICelera
Cytogenetic Map2q45NCBI
Ptger3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542321,096,926 - 21,164,435 (+)NCBIChiLan1.0ChiLan1.0
PTGER3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11154,996,361 - 155,091,432 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0170,076,610 - 70,271,475 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1172,058,998 - 72,254,063 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,059,441 - 72,254,063 (-)Ensemblpanpan1.1panPan2
PTGER3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1674,932,789 - 74,986,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha677,575,622 - 77,753,496 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0675,490,852 - 75,668,770 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl675,490,852 - 75,714,812 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1675,042,922 - 75,220,964 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0674,940,272 - 75,118,118 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0675,437,418 - 75,616,001 (+)NCBIUU_Cfam_GSD_1.0
Ptger3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505883,239,312 - 83,315,450 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365911,174,069 - 1,249,410 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365911,174,364 - 1,250,233 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGER3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6141,958,955 - 142,161,286 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16141,958,955 - 142,160,437 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26131,574,664 - 131,776,520 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGER3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12062,093,830 - 62,293,360 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2062,095,458 - 62,174,959 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603355,495,971 - 55,576,801 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptger3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474225,177,340 - 25,356,911 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptger3
2287 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1830
Count of miRNA genes:521
Interacting mature miRNAs:636
Transcripts:ENSMUST00000041175, ENSMUST00000173533
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse

Markers in Region
09.mHAa3d9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,616,412 - 157,616,585UniSTSGRCm38
MGSCv373157,279,376 - 157,279,549UniSTSGRCm37
Celera3164,084,756 - 164,084,929UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
Whitehead_YAC3 UniSTS
D17406  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,605,934 - 157,606,040UniSTSGRCm38
MGSCv373157,268,898 - 157,269,004UniSTSGRCm37
Celera3164,074,311 - 164,074,417UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
Whitehead/MRC_RH31740.63UniSTS
D10204  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,644,006 - 157,644,171UniSTSGRCm38
MGSCv373157,306,970 - 157,307,135UniSTSGRCm37
Celera3164,112,361 - 164,112,526UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
Whitehead/MRC_RH31743.43UniSTS
UniSTS:234856  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,644,473 - 157,644,693UniSTSGRCm38
MGSCv373157,307,437 - 157,307,657UniSTSGRCm37
Celera3164,112,828 - 164,113,048UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
AI844685  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,610,319 - 157,610,433UniSTSGRCm38
MGSCv373157,273,283 - 157,273,397UniSTSGRCm37
Celera3164,078,697 - 164,078,811UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
Whitehead/MRC_RH16979.26UniSTS
PMC327192P4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,644,129 - 157,644,530UniSTSGRCm38
MGSCv373157,307,093 - 157,307,494UniSTSGRCm37
Celera3164,112,484 - 164,112,885UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
PMC197251P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,567,189 - 157,567,583UniSTSGRCm38
MGSCv373157,230,153 - 157,230,547UniSTSGRCm37
Celera3164,035,190 - 164,035,584UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
Ptger3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,607,217 - 157,607,423UniSTSGRCm38
MGSCv373157,270,181 - 157,270,387UniSTSGRCm37
Celera3164,075,594 - 164,075,800UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS
Ptger3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383157,644,458 - 157,644,614UniSTSGRCm38
MGSCv373157,307,422 - 157,307,578UniSTSGRCm37
Celera3164,112,813 - 164,112,969UniSTS
Cytogenetic Map3H4UniSTS
cM Map382.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000041175   ⟹   ENSMUSP00000043302
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,272,529 - 157,351,525 (+)Ensembl
GRCm38.p6 Ensembl3157,566,892 - 157,645,888 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173533   ⟹   ENSMUSP00000134137
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,272,537 - 157,350,393 (+)Ensembl
GRCm38.p6 Ensembl3157,566,900 - 157,644,756 (+)Ensembl
RefSeq Acc Id: ENSMUST00000196682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,272,537 - 157,313,232 (+)Ensembl
GRCm38.p6 Ensembl3157,566,900 - 157,607,595 (+)Ensembl
RefSeq Acc Id: NM_001359745   ⟹   NP_001346674
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,272,513 - 157,350,392 (+)NCBI
GRCm383157,566,876 - 157,644,755 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011196   ⟹   NP_035326
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,272,513 - 157,350,392 (+)NCBI
GRCm383157,566,876 - 157,644,755 (+)NCBI
MGSCv373157,229,856 - 157,307,722 (+)RGD
Celera3164,034,893 - 164,113,113 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501140   ⟹   XP_006501203
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,272,459 - 157,350,392 (+)NCBI
GRCm383157,566,822 - 157,644,758 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011240038   ⟹   XP_011238340
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,272,459 - 157,349,599 (+)NCBI
GRCm383157,566,821 - 157,643,962 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035326   ⟸   NM_011196
- Peptide Label: isoform 2
- UniProtKB: P30557 (UniProtKB/Swiss-Prot),   Q6PDF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501203   ⟸   XM_006501140
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011238340   ⟸   XM_011240038
- Peptide Label: isoform X1
- UniProtKB: P30557 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346674   ⟸   NM_001359745
- Peptide Label: isoform 1
- UniProtKB: P30557 (UniProtKB/Swiss-Prot),   G3UYL9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000134137   ⟸   ENSMUST00000173533
RefSeq Acc Id: ENSMUSP00000043302   ⟸   ENSMUST00000041175
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30557-F1-model_v2 AlphaFold P30557 1-365 view protein structure

Promoters
RGD ID:6834323
Promoter ID:MM_KWN:36500
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:ENSMUST00000071906,   NM_011196,   UC008RVG.1,   UC008RVI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363157,229,909 - 157,230,409 (+)MPROMDB
RGD ID:6882698
Promoter ID:EPDNEW_M4799
Type:multiple initiation site
Name:Ptger3_1
Description:Mus musculus prostaglandin E receptor 3 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383157,566,876 - 157,566,936EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97795 AgrOrtholog
Ensembl Genes ENSMUSG00000040016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041175 ENTREZGENE
  ENSMUST00000041175.13 UniProtKB/TrEMBL
  ENSMUST00000173533 ENTREZGENE
  ENSMUST00000173533.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EP3_rcpt_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostanoid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_DP_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_EP3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97795 ENTREZGENE
NCBI Gene 19218 ENTREZGENE
PANTHER PTHR11866 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11866:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptger3 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROSTAGLNDNR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROSTANOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRSTNOIDE33R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRSTNOIDEP3R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3UYL9 ENTREZGENE, UniProtKB/TrEMBL
  P30557 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6PDF2 ENTREZGENE, UniProtKB/TrEMBL